All Stories

  1. DNAJA1 dysregulates metabolism promoting an anti-apoptotic phenotype in pancreatic ductal adenocarcinoma

    Article • September 2020, Research Square

    Dr Robert Powers

  2. Phosphorus NMR and Its Application to Metabolomics

    Article • Analytical Chemistry, June 2020, American Chemical Society (ACS)

    Dr Robert Powers

  3. Evaluation of Non-Uniform Sampling 2D 1H–13C HSQC Spectra for Semi-Quantitative Metabolomics

    Article • Metabolites, May 2020, MDPI AG

    Dr Robert Powers

  4. Evaluation of Multivariate Classification Models for Analyzing NMR Metabolomics Data

    Article • Journal of Proteome Research, August 2019, American Chemical Society (ACS)

    Dr Robert Powers

  5. Understanding interactions of Citropin 1.1 analogues with model membranes and their influence on biological activity

    Article • Peptides, July 2019, Elsevier

    Dr Robert Powers

  6. Novel Amphiphilic Cyclobutene and Cyclobutane cis-C18 Fatty Acid Derivatives Inhibit Mycobacterium avium subsp. paratuberculosis Growth

    Article • Veterinary Sciences, May 2019, MDPI AG

    Dr Robert Powers

  7. O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Interacting Serine/Threonine-Protein Kinase 3

    Article • Immunity, April 2019, Elsevier

    Dr Robert Powers

  8. Functional Evolution of Proteins

    Article • Proteins Structure Function and Bioinformatics, February 2019, Wiley

    Dr Robert Powers

  9. Urease is an essential component of the acid response network of Staphylococcus aureus and is required for a persistent murine kidney infection

    Article • PLoS Pathogens, January 2019, PLOS

    Dr Robert Powers, Paul Fey

  10. Insights into gemcitabine resistance and the potential for therapeutic monitoring

    Article • Metabolomics, November 2018, Springer Science + Business Media

    Dr Robert Powers

  11. Combining Mass Spectrometry and NMR Improves Metabolite Detection and Annotation

    Article • Journal of Proteome Research, October 2018, American Chemical Society (ACS)

    Dr Robert Powers

  12. Comparing normalization methods and the impact of noise

    Article • Metabolomics, August 2018, Springer Science + Business Media

    Dr Robert Powers

  13. Expanding the Coverage of the Metabolome with Nitrogen-Based NMR

    Article • Analytical Chemistry, March 2018, American Chemical Society (ACS)

    Dr Robert Powers

  14. 15 N CEST data and traditional model-free analysis capture fast internal dynamics of DJ-1

    Article • Analytical Biochemistry, February 2018, Elsevier

    Dr Robert Powers

  15. Metabolic Mitigation of Staphylococcus aureus Vancomycin Intermediate-Level Susceptibility

    Article • Antimicrobial Agents and Chemotherapy, November 2017, ASM Journals

    Dr Robert Powers, Dr Greg A Somerville

  16. Glucose Limitation Alters Glutamine Metabolism in MUC1-Overexpressing Pancreatic Cancer Cells

    Article • Journal of Proteome Research, August 2017, American Chemical Society (ACS)

    Dr Robert Powers

  17. Nanoformulated Copper/Zinc Superoxide Dismutase Exerts Differential Effects on Glucose versus Lipid Homeostasis Depending on the Diet Composition Possibly via Altered AMPK Signaling

    Article • Translational Research, August 2017, Elsevier

    Dr Robert Powers

  18. New frontiers in metabolomics: from measurement to insight

    Article • F1000Research, July 2017, Faculty of 1000, Ltd.

    Dr Robert Powers, Eli Riekeberg

  19. Metabolic Investigations of the Molecular Mechanisms Associated with Parkinson’s Disease

    Article • Metabolites, May 2017, MDPI AG

    Dr Robert Powers

  20. Assessment of Metabolic Changes in Mycobacterium smegmatis Wild-Type and alr Mutant Strains: Evidence of a New Pathway of d-Alanine Biosynthesis

    Article • Journal of Proteome Research, February 2017, American Chemical Society (ACS)

    Dr Robert Powers

  21. Amino Acid Catabolism in Staphylococcus aureus and the Function of Carbon Catabolite Repression

    Article • mBio, February 2017, ASM Journals

    Dr Robert Powers, Paul Fey

  22. Identification of a Ligand-Binding Site on the Staphylococcus aureus DnaG Primase C-Terminal Domain

    Article • Biochemistry, February 2017, American Chemical Society (ACS)

    Dr Robert Powers

  23. PCA as a Practical Indicator of OPLS-DA Model Reliability

    Article • Current Metabolomics, June 2016, Bentham Science Publishers

    Dr Robert Powers

  24. Deterministic multidimensional nonuniform gap sampling

    Article • Journal of Magnetic Resonance, December 2015, Elsevier

    Dr Robert Powers

  25. Staphylococcus aureus Metabolic Adaptations during the Transition from a Daptomycin Susceptibility Phenotype to a Daptomycin Nonsusceptibility Phenotype

    Article • Antimicrobial Agents and Chemotherapy, May 2015, ASM Journals

    Dr Greg A Somerville, Dr Robert Powers, Rosmarie Gaupp

  26. Meet Our Editor

    Article • Current Metabolomics, May 2015, Bentham Science Publishers

    Dr Robert Powers

  27. Preface: “The Whole is Greater Than the Sum of its Parts.” - Aristotle

    Article • Current Metabolomics, May 2015, Bentham Science Publishers

    Dr Robert Powers

  28. Faculty of 1000 evaluation for Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway.

    Article • March 2015, Faculty of 1000, Ltd.

    Dr Robert Powers

  29. Editorial

    Article • Current Metabolomics, April 2014, Bentham Science Publishers

    Dr Robert Powers

  30. Simultaneous phase and scatter correction for NMR datasets

    Article • Chemometrics and Intelligent Laboratory Systems, February 2014, Elsevier

    Dr Robert Powers

  31. Revisiting Protocols for the NMR Analysis of Bacterial Metabolomes

    Article • Journal of Integrated OMICS, December 2013, Proteomass

    Dr Robert Powers, Rosmarie Gaupp

  32. Growth and Preparation of Staphylococcus epidermidis for NMR Metabolomic Analysis

    Article • October 2013, Springer Science + Business Media

    Dr Greg A Somerville, Dr Robert Powers

  33. NMR Metabolomics Analysis of Parkinson's Disease

    Article • Current Metabolomics, September 2013, Bentham Science Publishers

    Dr Robert Powers

  34. Faculty of 1000 evaluation for Digestion and depletion of abundant proteins improves proteomic coverage.

    Article • February 2013, Faculty of 1000, Ltd.

    Dr Robert Powers

  35. Faculty of 1000 evaluation for Metabolite-enabled eradication of bacterial persisters by aminoglycosides.

    Article • February 2013, Faculty of 1000, Ltd.

    Dr Robert Powers

  36. NMR in Drug Discovery – Introduction

    Article • January 2013, Springer Science + Business Media

    Dr Robert Powers

  37. Fragment Screen

    Article • January 2013, Springer Science + Business Media

    Dr Robert Powers

  38. SAR by NMR

    Article • January 2013, Springer Science + Business Media

    Dr Robert Powers

  39. The Applicability of Molecular Descriptors for Designing an Electrospray Ionization Mass Spectrometry Compatible Library for Drug Discovery

    Article • Combinatorial Chemistry & High Throughput Screening, November 2012, Bentham Science Publishers

    Dr Robert Powers

  40. Editorial

    Article • Current Metabolomics, November 2012, Bentham Science Publishers

    Dr Robert Powers

  41. Editorial

    Article • Current Metabolomics, November 2012, Bentham Science Publishers

    Dr Robert Powers

  42. Multivariate Analysis in Metabolomics

    Article • Current Metabolomics, November 2012, Bentham Science Publishers

    Dr Robert Powers

  43. Multivariate Analysis in Metabolomics

    Article • Current Metabolomics, November 2012, Bentham Science Publishers

    Dr Robert Powers

  44. Sample Preparation of Mycobacterium tuberculosis Extracts for Nuclear Magnetic Resonance Metabolomic Studies

    Article • Journal of Visualized Experiments, September 2012, MyJove Corporation

    Dr Robert Powers

  45. Application of NMR Metabolomics to Search for Human Disease Biomarkers

    Article • Combinatorial Chemistry & High Throughput Screening, August 2012, Bentham Science Publishers

    Dr Robert Powers

  46. Analysis of bacterial biofilms using NMR-based metabolomics

    Article • Future Medicinal Chemistry, June 2012, Future Science

    Dr Robert Powers

  47. Predicting the in Vivo Mechanism of Action for Drug Leads Using NMR Metabolomics

    Article • ACS Chemical Biology, January 2012, American Chemical Society (ACS)

    Dr Robert Powers

  48. An inexpensive high-throughput nuclear magnetic resonance tube cleaning apparatus

    Article • Analytical Biochemistry, September 2011, Elsevier

    Dr Robert Powers, Dr Bo Zhang

  49. Faculty of 1000 evaluation for Paper spray for direct analysis of complex mixtures using mass spectrometry.

    Article • August 2011, Faculty of 1000, Ltd.

    Dr Robert Powers

  50. Bacterial protein structures reveal phylum dependent divergence

    Article • Computational Biology and Chemistry, February 2011, Elsevier

    Dr Robert Powers

  51. Faculty of 1000 evaluation for A transient and low-populated protein-folding intermediate at atomic resolution.

    Article • December 2010, Faculty of 1000, Ltd.

    Dr Robert Powers

  52. Faculty of 1000 evaluation for Enzymatic transition states and dynamic motion in barrier crossing.

    Article • December 2010, Faculty of 1000, Ltd.

    Dr Robert Powers

  53. Faculty of 1000 evaluation for Molecular docking and ligand specificity in fragment-based inhibitor discovery.

    Article • May 2010, Faculty of 1000, Ltd.

    Dr Robert Powers

  54. Faculty of 1000 evaluation for Evaluation of virtual screening as a tool for chemical genetic applications.

    Article • May 2010, Faculty of 1000, Ltd.

    Dr Robert Powers

  55. Faculty of 1000 evaluation for Mapping of ligand-binding cavities in proteins.

    Article • May 2010, Faculty of 1000, Ltd.

    Dr Robert Powers

  56. Faculty of 1000 evaluation for A hybrid clustering of protein binding sites.

    Article • May 2010, Faculty of 1000, Ltd.

    Dr Robert Powers

  57. Analysis of metabolomic PCA data using tree diagrams

    Article • Analytical Biochemistry, April 2010, Elsevier

    Dr Robert Powers

  58. Faculty of 1000 evaluation for Systems biology: an evolving approach in drug discovery and development.

    Article • October 2009, Faculty of 1000, Ltd.

    Dr Robert Powers

  59. Advances in nuclear magnetic resonance for drug discovery

    Article • Expert Opinion on Drug Discovery, August 2009, Informa Healthcare

    Dr Robert Powers

  60. Faculty of 1000 evaluation for Structure and energetics of the hydrogen-bonded backbone in protein folding.

    Article • July 2009, Faculty of 1000, Ltd.

    Dr Robert Powers

  61. NMR metabolomics and drug discovery

    Article • Magnetic Resonance in Chemistry, June 2009, Wiley

    Dr Robert Powers

  62. Faculty of 1000 evaluation for Metabolite identification via the Madison Metabolomics Consortium Database.

    Article • May 2009, Faculty of 1000, Ltd.

    Dr Robert Powers

  63. Faculty of 1000 evaluation for Binding similarity network of ligand.

    Article • June 2008, Faculty of 1000, Ltd.

    Dr Robert Powers

  64. Faculty of 1000 evaluation for Protein dispensability and rate of evolution.

    Article • December 2007, Faculty of 1000, Ltd.

    Dr Robert Powers

  65. Functional Genomics and NMR Spectroscopy

    Article • Combinatorial Chemistry & High Throughput Screening, September 2007, Bentham Science Publishers

    Dr Robert Powers

  66. Faculty of 1000 evaluation for Enzyme function less conserved than anticipated.

    Article • July 2007, Faculty of 1000, Ltd.

    Dr Robert Powers

  67. Faculty of 1000 evaluation for Intrinsic errors in genome annotation.

    Article • July 2007, Faculty of 1000, Ltd.

    Dr Robert Powers

  68. Faculty of 1000 evaluation for Discovering high-affinity ligands for proteins: SAR by NMR.

    Article • July 2007, Faculty of 1000, Ltd.

    Dr Robert Powers

  69. Faculty of 1000 evaluation for Evolutionary rate in the protein interaction network.

    Article • April 2007, Faculty of 1000, Ltd.

    Dr Robert Powers

  70. APPLICATIONS OF NUCLEAR MAGNETIC RESONANCE AND MASS SPECTROMETRY TO ANTICANCER DRUG DISCOVERY

    Article • January 2006, Elsevier

    Dr Robert Powers

  71. Solution structure of the tumor necrosis factor receptor-1 death domain

    Article • Journal of Molecular Biology, July 2001, Elsevier

    Dr Robert Powers

  72. Analysis of the backbone dynamics of the ribonuclease H domain of the human immunodeficiency virus reverse transcriptase using nitrogen-15 relaxation measurements

    Article • Biochemistry, September 1992, American Chemical Society (ACS)

    Dr G. Marius Clore, Dr Robert Powers

  73. Three-Dimensional Solution Structure of Human Interleukin-4 by Multidimensional Heteronuclear Magnetic Resonance Spectroscopy

    Article • Science, June 1992, American Association for the Advancement of Science

    Dr Robert Powers

  74. Proton, nitrogen-15, carbon-13, carbon-13 monoxide assignments of human interleukin-4 using three-dimensional double- and triple-resonance heteronuclear magnetic resonance spectroscopy

    Article • Biochemistry, May 1992, American Chemical Society (ACS)

    Dr G. Marius Clore, Dr Robert Powers

  75. Determination of the secondary structure and folding topology of human interleukin-4 using three-dimensional heteronuclear magnetic resonance spectroscopy

    Article • Biochemistry, May 1992, American Chemical Society (ACS)

    Dr G. Marius Clore, Dr Robert Powers

  76. Secondary structure of the ribonuclease H domain of the human immunodeficiency virus reverse transcriptase in solution using three-dimensional double and triple resonance heteronuclear magnetic resonance spectroscopy

    Article • Journal of Molecular Biology, October 1991, Elsevier

    Dr G. Marius Clore, Dr Robert Powers

  77. A common sense approach to peak picking in two-, three-, and four-dimensional spectra using automatic computer analysis of contour diagrams

    Article • Journal of Magnetic Resonance (1969), October 1991, Elsevier

    Dr Robert Powers

  78. Three-dimensional triple-resonance NMR of 13C/15N-enriched proteins using constant-time evolution

    Article • Journal of Magnetic Resonance (1969), August 1991, Elsevier

    Dr G. Marius Clore, Dr Robert Powers

  79. Two-dimensional proton and phosphorus-31 NMR spectra and restrained molecular dynamics structure of a covalent CPI-CDPI2-oligodeoxyribonucleotide decamer complex

    Article • Biochemistry, October 1990, American Chemical Society (ACS)

    Dr Robert Powers

  80. Introduction to NMR and Its Application in Metabolite Structure Determination

    Article • Wiley

    Dr Robert Powers