All Stories

  1. NAD(P)H:quinone oxidoreductase 1 inducer activity of some novel anilinoquinazoline derivatives

    Article • Drug Design Development and Therapy, August 2016, Dove Medical Press

    Dr Reem K. Arafa, Professor Abdelaaty A Shahat, Nehal Elghazawy, mostafa Ghorab

  2. Novel pyrrole derivatives as selective CHK1 inhibitors: design, regioselective synthesis and molecular modeling

    Article • MedChemComm, January 2015, Royal Society of Chemistry

    Dr Reem K. Arafa

  3. Correction: Novel pyrrole derivatives as selective CHK1 inhibitors: design, regioselective synthesis and molecular modeling

    Article • MedChemComm, January 2015, Royal Society of Chemistry

    Dr Reem K. Arafa

  4. Anticancer, antioxidant activities, and DNA affinity of novel monocationic bithiophenes and analogues

    Article • Drug Design Development and Therapy, September 2014, Taylor & Francis

    Professor Wael M El-Sayed, Dr Magdy M Youssef, Dr Reem K. Arafa

  5. Design, Synthesis and Potential Anti-Proliferative Activity of Some Novel 4-Aminoquinoline Derivatives

    Article • Acta Pharmaceutica, September 2014, De Gruyter

    Dr Reem K. Arafa

  6. Phenolics of Achillea fragrantissima growing in Egypt and its cytotoxic activity

    Article • Journal of Medicinal Plants Research, June 2014, Academic Journals

    Dr Reem K. Arafa

  7. Synthesis, molecular modeling and NAD(P)H:quinone oxidoreductase 1 inducer activity of novel cyanoenone and enone benzenesulfonamides

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, January 2014, Taylor & Francis

    Professor Abdelaaty A Shahat, Dr Reem K. Arafa

  8. Novel anti-HIV-1 NNRTIs based on a pyrazolo[4,3-d]isoxazole backbone scaffold: design, synthesis and insights into the molecular basis of action

    Article • MedChemComm, January 2014, Royal Society of Chemistry

    Dr Reem K. Arafa

  9. Novel heterocyclic-fused pyrimidine derivatives: Synthesis, molecular modeling and pharmacological screening

    Article • European Journal of Medicinal Chemistry, November 2013, Elsevier

    Dr Reem K. Arafa

  10. Synthesis and Antiprotozoal Activity of Dicationic m -Terphenyl and 1,3-Dipyridylbenzene Derivatives

    Article • Journal of Medicinal Chemistry, July 2013, American Chemical Society (ACS)

    Dr Reem K. Arafa

  11. Synthesis and in vitro antiproliferative effect of novel quinoline-based potential anticancer agents

    Article • European Journal of Medicinal Chemistry, May 2013, Elsevier

    Professor Ashraf H. Abadi, Dr Reem K. Arafa

  12. Molecular modeling study and synthesis of novel dicationic flexible triaryl guanidines and imidamides as antiprotozoal agents

    Article • European Journal of Medicinal Chemistry, December 2011, Elsevier

    Dr Reem K. Arafa

  13. Docking study, in vitro anticancer screening and radiosensitizing evaluation of some new fluorine-containing quinoline and pyrimidoquinoline derivatives bearing a sulfonamide moiety

    Article • Medicinal Chemistry Research, March 2010, Springer Science + Business Media

    Dr Reem K. Arafa

  14. ChemInform Abstract: Design and Synthesis of Novel Benzopyran-2-one Derivatives of Expected Antimicrobial Activity Through DNA Gyrase-B Inhibition.

    Article • ChemInform, March 2009, Wiley

    Dr Reem K. Arafa

  15. Synthesis and antiprotozoal activity of novel bis-benzamidino imidazo[1,2-a]pyridines and 5,6,7,8-tetrahydro-imidazo[1,2-a]pyridines

    Article • Bioorganic & Medicinal Chemistry, January 2008, Elsevier

    Dr Reem K. Arafa

  16. Induced Fit Conformational Changes of a “Reversed Amidine” Heterocycle:  Optimized Interactions in a DNA Minor Groove Complex

    Article • Journal of the American Chemical Society, May 2007, American Chemical Society (ACS)

    Dr Reem K. Arafa

  17. 3,5-Diarylisoxazoles: Individualized Three-Step Synthesis and Isomer Determination Using 13C NMR or Mass Spectroscopy

    Article • Journal of Chemical Education, September 2006, American Chemical Society (ACS)

    Dr Reem K. Arafa

  18. Synthesis, DNA Affinity, and Antiprotozoal Activity of Linear Dications:  Terphenyl Diamidines and Analogues

    Article • Journal of Medicinal Chemistry, August 2006, American Chemical Society (ACS)

    Dr Reem K. Arafa

  19. Synthesis, DNA Affinity, and Antiprotozoal Activity of Fused Ring Dicationic Compounds and Their Prodrugs

    Article • Journal of Medicinal Chemistry, August 2005, American Chemical Society (ACS)

    Dr Reem K. Arafa

  20. Molecular Determinants for DNA Minor Groove Recognition:  Design of a Bis-Guanidinium Derivative of Ethidium That Is Highly Selective for AT-Rich DNA Sequences †

    Article • Biochemistry, February 2005, American Chemical Society (ACS)

    Dr Reem K. Arafa

  21. SYNTHESIS OF DICATIONIC 2,5-DIARYLPYRROLES

    Article • Heterocyclic Communications, January 2004, De Gruyter

    Dr Reem K. Arafa