All Stories

  1. Cmr3 regulates the suppression on cyclic oligoadenylate synthesis by tag complementarity in a Type III-B CRISPR-Cas system

    Article • RNA Biology, July 2019, Taylor & Francis

    Tong Guo, Dr Qunxin She

  2. A seed motif for target RNA capture enables efficient immune defence by a type III-B CRISPR-Cas system

    Article • RNA Biology, May 2019, Taylor & Francis

    Dr Qunxin She

  3. A Type III-B Cmr effector complex catalyzes the synthesis of cyclic oligoadenylate second messengers by cooperative substrate binding

    Article • Nucleic Acids Research, September 2018, Oxford University Press (OUP)

    Dr Qunxin She

  4. Comprehensive search for accessory proteins encoded with archaeal and bacterial type III CRISPR-cas gene cassettes reveals 39 new cas gene families

    Article • RNA Biology, June 2018, Taylor & Francis

    Dr Qunxin She

  5. An Orc1/Cdc6 ortholog functions as a key regulator in the DNA damage response in Archaea

    Article • Nucleic Acids Research, June 2018, Oxford University Press (OUP)

    Dr Qunxin She

  6. Tolerance of Sulfolobus SMV1 virus to the immunity of I-A and III-B CRISPR-Cas systems in Sulfolobus islandicus

    Article • RNA Biology, April 2018, Taylor & Francis

    Tong Guo, Dr Qunxin She

  7. A transcriptional factor B paralog functions as an activator to DNA damage-responsive expression in archaea

    Article • Nucleic Acids Research, March 2018, Oxford University Press (OUP)

    Dr Qunxin She

  8. Conserved accessory proteins encoded with archaeal and bacterial Type III CRISPR-Cas gene cassettes that may specifically modulate, complement or extend interference activity

    Article • February 2018, Cold Spring Harbor Laboratory Press

    Dr Qunxin She

  9. Cmr1 enables efficient RNA and DNA interference of a III-B CRISPR–Cas system by binding to target RNA and crRNA

    Article • Nucleic Acids Research, September 2017, Oxford University Press (OUP)

    Dr Qunxin She

  10. Allosteric regulation of Csx1, a type IIIB-associated CARF domain ribonuclease by RNAs carrying a tetraadenylate tail

    Article • Nucleic Acids Research, August 2017, Oxford University Press (OUP)

    Dr Qunxin She

  11. Coupling transcriptional activation of CRISPR–Cas system and DNA repair genes by Csa3a in Sulfolobus islandicus

    Article • Nucleic Acids Research, July 2017, Oxford University Press (OUP)

    Dr Qunxin She

  12. Reverse Gyrase Functions in Genome Integrity Maintenance by Protecting DNA Breaks In Vivo

    Article • International Journal of Molecular Sciences, June 2017, MDPI AG

    Dr Qunxin She

  13. Genomic and transcriptomic analyses reveal distinct biological functions for cold shock proteins (VpaCspA and VpaCspD) in Vibrio parahaemolyticus CHN25 during low-temperature survival

    Article • BMC Genomics, June 2017, Springer Science + Business Media

    Dr Qunxin She

  14. Genetic technologies for extremely thermophilic microorganisms of Sulfolobus, the only genetically tractable genus of crenarchaea

    Article • Science in China Series C Life Sciences, February 2017, Springer Science + Business Media

    Dr Qunxin She

  15. Type III CRISPR-Cas System: Introduction And Its Application for Genetic Manipulations

    Article • January 2017, Caister Academic Press

    Dr Qunxin She

  16. A type III-B CRISPR-Cas effector complex mediating massive target DNA destruction

    Article • Nucleic Acids Research, December 2016, Oxford University Press (OUP)

    Dr Qunxin She

  17. CRISPR-Cas type I-A Cascade complex couples viral infection surveillance to host transcriptional regulation in the dependence of Csa3b

    Article • Nucleic Acids Research, December 2016, Oxford University Press (OUP)

    Dr Qunxin She

  18. Diverse CRISPR-Cas responses and dramatic cellular DNA changes and cell death in pKEF9-conjugatedSulfolobusspecies

    Article • Nucleic Acids Research, April 2016, Oxford University Press (OUP)

    Dr Qunxin She

  19. Theapt/6-Methylpurine Counterselection System and Its Applications in Genetic Studies of the Hyperthermophilic Archaeon Sulfolobus islandicus

    Article • Applied and Environmental Microbiology, March 2016, ASM Journals

    Dr Changyi Zhang, Dr Qunxin She

  20. Construction and characterization of three protein-targeting expression system inLactobacillus casei

    Article • FEMS Microbiology Letters, February 2016, Oxford University Press (OUP)

    Dr Qunxin She

  21. Heterologous Expression of Mannanase and Developing a New Reporter Gene System in Lactobacillus casei and Escherichia coli

    Article • PLoS ONE, November 2015, PLOS

    Dr Qunxin She

  22. Transcriptome analysis of Sulfolobus solfataricus infected with two related fuselloviruses reveals novel insights into the regulation of CRISPR-Cas system

    Article • Biochimie, November 2015, Elsevier

    Dr Qunxin She

  23. Harnessing Type I and Type III CRISPR-Cas systems for genome editing

    Article • Nucleic Acids Research, October 2015, Oxford University Press (OUP)

    Dr Qunxin She

  24. Unravelling the Role of the F55 Regulator in the Transition from Lysogeny to UV Induction of Sulfolobus Spindle-Shaped Virus 1

    Article • Journal of Virology, April 2015, ASM Journals

    Dr Qunxin She

  25. CRISPR-Cas Adaptive Immune Systems of the Sulfolobales: Unravelling Their Complexity and Diversity

    Article • Life, March 2015, MDPI AG

    Dr Qunxin She, Susanne Erdmann

  26. Archaeal Extrachromosomal Genetic Elements

    Article • Microbiology and Molecular Biology Reviews, February 2015, ASM Journals

    Dr Qunxin She

  27. Genetic analysis of the Holliday junction resolvases Hje and Hjc in Sulfolobus islandicus

    Article • World Journal of Surgery, February 2015, Springer Science + Business Media

    Dr Qunxin She

  28. Transcriptional regulator-mediated activation of adaptation genes triggers CRISPR de novo spacer acquisition

    Article • Nucleic Acids Research, January 2015, Oxford University Press (OUP)

    Dr Qunxin She

  29. Efficient 5′-3′ DNA end resection by HerA and NurA is essential for cell viability in the crenarchaeon Sulfolobus islandicus

    Article • BMC Molecular Biology, January 2015, Springer Science + Business Media

    Dr Qunxin She

  30. An archaeal CRISPR type III-B system exhibiting distinctive RNA targeting features and mediating dual RNA and DNA interference

    Article • Nucleic Acids Research, December 2014, Oxford University Press (OUP)

    Dr Qunxin She

  31. Sulfolobus Replication Factor C Stimulates the Activity of DNA Polymerase B1

    Article • Journal of Bacteriology, April 2014, ASM Journals

    Dr Qunxin She

  32. Characterization of pMC11, a plasmid with dual origins of replication isolated from Lactobacillus casei MCJ and construction of shuttle vectors with each replicon

    Article • Applied Microbiology and Biotechnology, March 2014, Springer Science + Business Media

    Dr Qunxin She

  33. Molecular biology of fuselloviruses and their satellites

    Article • World Journal of Surgery, February 2014, Springer Science + Business Media

    Dr Qunxin She

  34. Nanobiomotors of archaeal DNA repair machineries: current research status and application potential

    Article • Cell & Bioscience, January 2014, Springer Science + Business Media

    Dr Qunxin She

  35. A novel single-tailed fusiform Sulfolobus virus STSV2 infecting model Sulfolobus species

    Article • World Journal of Surgery, October 2013, Springer Science + Business Media

    Dr Qunxin She, Susanne Erdmann

  36. Knockouts of RecA-Like Proteins RadC1 and RadC2 Have Distinct Responses to DNA Damage Agents in Sulfolobus islandicus

    Article • Journal of Genetics and Genomics, October 2013, Elsevier

    Dr Qunxin She

  37. Transcriptomic analysis of the SSV2 infection of Sulfolobus solfataricus with and without the integrative plasmid pSSVi

    Article • Virology, July 2013, Elsevier

    Dr Qunxin She

  38. Genomics and genetics of Sulfolobus islandicus LAL14/1, a model hyperthermophilic archaeon

    Article • Open Biology, April 2013, Royal Society Publishing

    Dr Qunxin She

  39. Novel insights into gene regulation of the rudivirus SIRV2 infectingSulfolobuscells

    Article • RNA Biology, April 2013, Taylor & Francis

    Dr Qunxin She

  40. Tlys, a Newly Identified Sulfolobus Spindle-Shaped Virus 1 Transcript Expressed in the Lysogenic State, Encodes a DNA-Binding Protein Interacting at the Promoters of the Early Genes

    Article • Journal of Virology, March 2013, ASM Journals

    Dr Qunxin She

  41. Genetic determinants of PAM-dependent DNA targeting and pre-crRNA processing inSulfolobus islandicus

    Article • RNA Biology, February 2013, Taylor & Francis

    Dr Qunxin She

  42. A novel interference mechanism by a type IIIB CRISPR-Cmr module inSulfolobus

    Article • Molecular Microbiology, February 2013, Wiley

    Dr Qunxin She

  43. Genetic manipulation inSulfolobus islandicusand functional analysis of DNA repair genes

    Article • Biochemical Society Transactions, February 2013, Portland Press Ltd.

    Dr Changyi Zhang, Dr Qunxin She

  44. Specificity and Function of Archaeal DNA Replication Initiator Proteins

    Article • Cell Reports, February 2013, Elsevier

    Dr Qunxin She

  45. A novel carboxyl-terminal protease derived from Paenibacillus lautus CHN26 exhibiting high activities at multiple sites of substrates

    Article • BMC Biotechnology, January 2013, Springer Science + Business Media

    Dr Qunxin She

  46. Molecular cloning of a novel bioH gene from an environmental metagenome encoding a carboxylesterase with exceptional tolerance to organic solvents

    Article • BMC Biotechnology, January 2013, Springer Science + Business Media

    Dr Qunxin She

  47. An archaeal protein evolutionarily conserved in prokaryotes is a zinc-dependent metalloprotease

    Article • Bioscience Reports, October 2012, Portland Press Ltd.

    Dr Qunxin She

  48. A Synthetic Arabinose-Inducible Promoter Confers High Levels of Recombinant Protein Expression in Hyperthermophilic Archaeon Sulfolobus islandicus

    Article • Applied and Environmental Microbiology, June 2012, ASM Journals

    Dr Qunxin She

  49. Archaeal viruses—novel, diverse and enigmatic

    Article • Science in China Series C Life Sciences, May 2012, Springer Science + Business Media

    Dr Qunxin She

  50. Dissection of the functional domains of an archaeal Holliday junction helicase

    Article • DNA Repair, February 2012, Elsevier

    Dr Qunxin She

  51. Modulation of CRISPR locus transcription by the repeat-binding protein Cbp1 in Sulfolobus

    Article • Nucleic Acids Research, December 2011, Oxford University Press (OUP)

    Dr Qunxin She

  52. Development of a Simvastatin Selection Marker for a Hyperthermophilic Acidophile, Sulfolobus islandicus

    Article • Applied and Environmental Microbiology, November 2011, ASM Journals

    Dr Changyi Zhang, Dr Qunxin She

  53. Exceptional thermal stability and organic solvent tolerance of an esterase expressed from a thermophilic host

    Article • Applied Microbiology and Biotechnology, August 2011, Springer Science + Business Media

    Dr Qunxin She

  54. Deletion of the topoisomerase III gene in the hyperthermophilic archaeon Sulfolobus islandicus results in slow growth and defects in cell cycle control

    Article • Journal of Genetics and Genomics, June 2011, Elsevier

    Dr Qunxin She

  55. Genomic analysis of Acidianus hospitalis W1 a host for studying crenarchaeal virus and plasmid life cycles

    Article • World Journal of Surgery, May 2011, Springer Science + Business Media

    Dr Qunxin She

  56. Sulfolobus Turreted Icosahedral Virus c92 Protein Responsible for the Formation of Pyramid-Like Cellular Lysis Structures

    Article • Journal of Virology, April 2011, ASM Journals

    Dr Qunxin She

  57. Structural and Functional Characterization of an Archaeal Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-associated Complex for Antiviral Defense (CASCADE)

    Article • Journal of Biological Chemistry, April 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Qunxin She

  58. C68 from theSulfolobus islandicusplasmid–virus pSSVx is a novel member of the AbrB-like transcription factor family

    Article • Biochemical Journal, April 2011, Portland Press Ltd.

    Dr Qunxin She

  59. Phenotypic, Proteomic, and Genomic Characterization of a Putative ABC-Transporter Permease Involved inListeria monocytogenesBiofilm Formation

    Article • Foodborne Pathogens and Disease, April 2011, Mary Ann Liebert Inc

    Dr Qunxin She

  60. Archaeal promoter architecture and mechanism of gene activation: Figure 1

    Article • Biochemical Society Transactions, February 2011, Portland Press Ltd.

    Dr Qunxin She

  61. CRISPR-based immune systems of the Sulfolobales: complexity and diversity

    Article • Biochemical Society Transactions, February 2011, Portland Press Ltd.

    Dr Qunxin She, Susanne Erdmann

  62. Genome Analyses of Icelandic Strains of Sulfolobus islandicus, Model Organisms for Genetic and Virus-Host Interaction Studies

    Article • Journal of Bacteriology, January 2011, ASM Journals

    Dr Qunxin She

  63. Dynamic properties of the Sulfolobus CRISPR/Cas and CRISPR/Cmr systems when challenged with vector-borne viral and plasmid genes and protospacers

    Article • Molecular Microbiology, November 2010, Wiley

    Dr Qunxin She

  64. Transcription termination in the plasmid/virus hybrid pSSVx from Sulfolobus islandicus

    Article • World Journal of Surgery, August 2010, Springer Science + Business Media

    Dr Qunxin She

  65. Revealing the essentiality of multiple archaeal pcna genes using a mutant propagation assay based on an improved knockout method

    Article • Microbiology, August 2010, Society for General Microbiology

    Dr Qunxin She

  66. Four newly isolated fuselloviruses from extreme geothermal environments reveal unusual morphologies and a possible interviral recombination mechanism

    Article • Environmental Microbiology, November 2009, Wiley

    Dr Qunxin She

  67. An upstream activation element exerting differential transcriptional activation on an archaeal promoter

    Article • Molecular Microbiology, October 2009, Wiley

    Dr Qunxin She

  68. Unmarked gene deletion and host–vector system for the hyperthermophilic crenarchaeon Sulfolobus islandicus

    Article • World Journal of Surgery, June 2009, Springer Science + Business Media

    Dr Qunxin She

  69. Genetic analyses in the hyperthermophilic archaeonSulfolobus islandicus

    Article • Biochemical Society Transactions, February 2009, Portland Press Ltd.

    Dr Changyi Zhang, Dr Qunxin She

  70. A Putative ABC Transporter Is Involved in Negative Regulation of Biofilm Formation by Listeria monocytogenes

    Article • Applied and Environmental Microbiology, October 2008, ASM Journals

    Dr Qunxin She

  71. Nucleotide sequence of pOLA52: A conjugative IncX1 plasmid from Escherichia coli which enables biofilm formation and multidrug efflux

    Article • Plasmid, July 2008, Elsevier

    Dr Qunxin She

  72. Transcriptional Analysis of the Genetic Element pSSVx: Differential and Temporal Regulation of Gene Expression Reveals Correlation between Transcription and Replication

    Article • Journal of Bacteriology, June 2007, ASM Journals

    Dr Qunxin She

  73. A novel Sulfolobus non-conjugative extrachromosomal genetic element capable of integration into the host genome and spreading in the presence of a fusellovirus

    Article • Virology, June 2007, Elsevier

    Dr Qunxin She

  74. The genome ofHyperthermus butylicus: a sulfur-reducing, peptide fermenting, neutrophilic Crenarchaeote growing up to 108 °C

    Article • Archaea, January 2007, Hindawi Publishing Corporation

    Dr Qunxin She

  75. Novel bacterial sulfur oxygenase reductases from bioreactors treating gold-bearing concentrates

    Article • Applied Microbiology and Biotechnology, November 2006, Springer Science + Business Media

    Dr Qunxin She

  76. Characterization of the Sulfolobus host–SSV2 virus interaction

    Article • World Journal of Surgery, August 2006, Springer Science + Business Media

    Dr Qunxin She

  77. The Genome of Sulfolobus acidocaldarius, a Model Organism of the Crenarchaeota

    Article • Journal of Bacteriology, July 2005, ASM Journals

    Dr Qunxin She

  78. Sulfolobus tengchongensis Spindle-Shaped Virus STSV1: Virus-Host Interactions and Genomic Features

    Article • Journal of Virology, July 2005, ASM Journals

    Dr Qunxin She

  79. Key Role of Cysteine Residues in Catalysis and Subcellular Localization of Sulfur Oxygenase-Reductase of Acidianus tengchongensis

    Article • Applied and Environmental Microbiology, February 2005, ASM Journals

    Dr Qunxin She

  80. Novel RepA-MCM proteins encoded in plasmids pTAU4, pORA1 and pTIK4 fromSulfolobus neozealandicus

    Article • Archaea, January 2005, Hindawi Publishing Corporation

    Dr Qunxin She

  81. Archaeal integrases and mechanisms of gene capture

    Article • Biochemical Society Transactions, April 2004, Portland Press Ltd.

    Dr Qunxin She

  82. Relationships between fuselloviruses infecting the extremely thermophilic archaeon Sulfolobus: SSV1 and SSV2

    Article • Research in Microbiology, May 2003, Elsevier

    Dr Qunxin She

  83. Genus-Specific Protein Binding to the Large Clusters of DNA Repeats (Short Regularly Spaced Repeats) Present in Sulfolobus Genomes

    Article • Journal of Bacteriology, April 2003, ASM Journals

    Dr Qunxin She

  84. Archaeal integrative genetic elements and their impact on genome evolution

    Article • Research in Microbiology, July 2002, Elsevier

    Dr Qunxin She

  85. Mobile elements in archaeal genomes

    Article • FEMS Microbiology Letters, January 2002, Oxford University Press (OUP)

    Dr Qunxin She

  86. Sequences and Replication of Genomes of the Archaeal Rudiviruses SIRV1 and SIRV2: Relationships to the Archaeal Lipothrixvirus SIFV and Some Eukaryal Viruses

    Article • Virology, December 2001, Elsevier

    Dr Qunxin She

  87. The complete genome of the crenarchaeon Sulfolobus solfataricus P2

    Article • Proceedings of the National Academy of Sciences, June 2001, Proceedings of the National Academy of Sciences

    Dr Qunxin She

  88. Non-autonomous mobile elements in the crenarchaeon Sulfolobus solfataricus

    Article • Journal of Molecular Biology, February 2001, Elsevier

    Dr Qunxin She

  89. Genome evolution: Gene capture in archaeal chromosomes

    Article • Nature, January 2001, Nature

    Dr Qunxin She

  90. pING Family of Conjugative Plasmids from the Extremely Thermophilic Archaeon Sulfolobus islandicus: Insights into Recombination and Conjugation in Crenarchaeota

    Article • Journal of Bacteriology, December 2000, ASM Journals

    Dr Qunxin She

  91. Evolution of the family of pRN plasmids and their integrase-mediated insertion into the chromosome of the crenarchaeon Sulfolobus solfataricus

    Article • Journal of Molecular Biology, November 2000, Elsevier

    Dr Qunxin She

  92. A Bac Library and Paired-PCR Approach to Mapping and Completing the Genome Sequence ofSulfolobus SolfataricusP2

    Article • DNA Sequence, January 2000, Taylor & Francis

    Dr Qunxin She

  93. Gene content and organization of a 281-kbp contig from the genome of the extremely thermophilic archaeon, Sulfolobus solfataricus P2

    Article • Genome, January 2000, Canadian Science Publishing

    Dr Qunxin She

  94. The genetic element pSSVx of the extremely thermophilic crenarchaeon Sulfolobus is a hybrid between a plasmid and a virus

    Article • Molecular Microbiology, October 1999, Wiley

    Dr Qunxin She

  95. Genetic profile of pNOB8 from Sulfolobus : the first conjugative plasmid from an archaeon

    Article • Extremophiles, November 1998, Springer Science + Business Media

    Professor Sonja-Verena Albers, Dr Qunxin She

  96. Sulfolobus genome: from genomics to biology

    Article • Current Opinion in Microbiology, October 1998, Elsevier

    Dr Qunxin She

  97. Completing the sequence of the Sulfolobus solfataricus P2 genome

    Article • World Journal of Surgery, August 1998, Springer Science + Business Media

    Dr Qunxin She

  98. Genetic elements in the extremely thermophilic archaeon Sulfolobus

    Article • World Journal of Surgery, August 1998, Springer Science + Business Media

    Dr Qunxin She

  99. Archaea and the new age of microorganisms

    Article • Trends in Ecology & Evolution, May 1998, Elsevier

    Dr Qunxin She

  100. Minimal enhancer elements of the leghemoglobinlba andlbc3 gene promoters fromGlycine max L. have different properties

    Article • Plant Molecular Biology, September 1993, Springer Science + Business Media

    Dr Qunxin She

  101. Comparative sequence analysis of cis elements present in Glycine max L. leghemoglobin lba and lbc3 genes

    Article • Plant Molecular Biology, August 1993, Springer Science + Business Media

    Dr Qunxin She