All Stories

  1. Patients with high c-MYC-expressing squamous cell carcinomas of the tongue show better survival than those with low- and medium-expressing tumours

    Article • Journal of Oral Pathology and Medicine, May 2017, Wiley

    Dr Philip J Coates, Prof Lorenzo Lo Muzio

  2. ΔNp63 activates EGFR signaling to induce loss of adhesion in triple-negative basal-like breast cancer cells

    Article • Breast Cancer Research and Treatment, March 2017, Springer Science + Business Media

    Dr Philip J Coates

  3. Gene expression changes in tumor free tongue tissue adjacent to tongue squamous cell carcinoma

    Article • Oncotarget, December 2016, Impact Journals, LLC

    Dr Philip J Coates

  4. Aldo-keto reductases are biomarkers of NRF2 activity and are co-ordinately overexpressed in non-small cell lung cancer

    Article • British Journal of Cancer, November 2016, Nature

    Dr Philip J Coates

  5. Epigenetic regulation of OAS2 shows disease-specific DNA methylation profiles at individual CpG sites

    Article • Scientific Reports, August 2016, Nature

    Dr Philip J Coates

  6. Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma

    Article • Nature Communications, August 2016, Nature

    Dr Philip J Coates

  7. ΔNp63 regulates cell proliferation, differentiation, adhesion, and migration in the BL2 subtype of basal-like breast cancer

    Article • Tumor Biology, January 2016, Springer Science + Business Media

    Dr Philip J Coates

  8. AGR2 oncoprotein inhibits p38 MAPK and p53 activation through a DUSP10-mediated regulatory pathway

    Article • Molecular Oncology, December 2015, Wiley

    Dr Philip J Coates

  9. Phosphorylation of a splice variant of collapsin response mediator protein 2 in the nucleus of tumour cells links cyclin dependent kinase-5 to oncogenesis

    Article • BMC Cancer, November 2015, Springer Science + Business Media

    Dr Philip J Coates

  10. Correlation between Reversal of DNA Methylation and Clinical Symptoms in Psoriatic Epidermis Following Narrow-Band UVB Phototherapy

    Article • Journal of Investigative Dermatology, August 2015, Elsevier

    Dr Philip J Coates

  11. Expression of p16 in squamous cell carcinoma of the mobile tongue is independent of HPV infection despite presence of the HPV-receptor syndecan-1

    Article • British Journal of Cancer, June 2015, Springer Science + Business Media

    Dr Philip J Coates, Prof Lorenzo Lo Muzio

  12. Downregulation of miRNA-424: a sign of field cancerisation in clinically normal tongue adjacent to squamous cell carcinoma

    Article • British Journal of Cancer, May 2015, Nature

    Dr Philip J Coates

  13. Book review

    Article • The Journal of Pathology, April 2015, Wiley

    Dr Philip J Coates

  14. Evidence for biological effects of metformin in operable breast cancer: biomarker analysis in a pre-operative window of opportunity randomized trial

    Article • Breast Cancer Research and Treatment, February 2015, Springer Science + Business Media

    Dr Philip J Coates

  15. The effect of 222-nm UVC phototesting on healthy volunteer skin: a pilot study

    Article • Photodermatology Photoimmunology & Photomedicine, January 2015, Wiley

    Dr Philip J Coates

  16. Oxidation Reduction is a Key Process for Successful Treatment of Psoriasis by Narrow-band UVB Phototherapy

    Article • Acta Dermato Venereologica, January 2015, Acta Dermato-Venereologica

    Dr Philip J Coates

  17. Viruses and disease: emerging concepts for prevention, diagnosis and treatment

    Article • The Journal of Pathology, December 2014, Wiley

    Dr Philip J Coates

  18. Predictive Gene Signatures: Molecular Markers Distinguishing Colon Adenomatous Polyp and Carcinoma

    Article • PLoS ONE, November 2014, PLOS

    Dr Philip J Coates

  19. Mutant p53 accumulation in human breast cancer is not an intrinsic property or dependent on structural or functional disruption but is regulated by exogenous stress and receptor status

    Article • The Journal of Pathology, May 2014, Wiley

    Dr Philip J Coates

  20. Lack of correlation of stem cell markers in breast cancer stem cells

    Article • British Journal of Cancer, February 2014, Nature

    Dr Philip J Coates

  21. Responses to ionizing radiation mediated by inflammatory mechanisms

    Article • The Journal of Pathology, January 2014, Wiley

    Dr Philip J Coates

  22. Expression of CXCL10 is associated with response to radiotherapy and overall survival in squamous cell carcinoma of the tongue

    Article • Tumor Biology, January 2014, Springer Science + Business Media

    Dr Philip J Coates

  23. Genes Involved in Epithelial Differentiation and Development are Differentially Expressed in Oral and Genital Lichen Planus Epithelium Compared to Normal Epithelium

    Article • Acta Dermato Venereologica, January 2014, Acta Dermato-Venereologica

    Dr Philip J Coates

  24. p53 and cell cycle independent dysregulation of autophagy in chronic lymphocytic leukaemia

    Article • British Journal of Cancer, October 2013, Nature

    Dr Philip J Coates

  25. Characterization of specific p63 and p63-N-terminal isoform antibodies and their application for immunohistochemistry

    Article • Virchows Archiv, July 2013, Springer Science + Business Media

    Dr Philip J Coates

  26. In Brief: cell senescence

    Article • The Journal of Pathology, June 2013, Wiley

    Dr Philip J Coates

  27. High expression of p63 is correlated to poor prognosis in squamous cell carcinoma of the tongue

    Article • Journal of Oral Pathology and Medicine, April 2013, Wiley

    Dr Philip J Coates

  28. The Influence of p53 Functions on Radiation-Induced Inflammatory Bystander-Type Signaling in Murine Bone Marrow

    Article • Radiation Research, April 2013, Radiation Research Society

    Dr Philip J Coates

  29. The Influence of p53 Functions on Radiation-Induced Inflammatory Bystander-Type Signaling in Murine Bone Marrow

    Article • Radiation Research, February 2013, Radiation Research Society

    Dr Philip J Coates

  30. Dysregulation of autophagy in chronic lymphocytic leukemia with the small-molecule Sirtuin inhibitor Tenovin-6

    Article • Scientific Reports, February 2013, Springer Science + Business Media

    Dr Philip J Coates

  31. Interactions of Apoptotic Cells with Macrophages in Radiation-Induced Bystander Signaling

    Article • Radiation Research, February 2013, Radiation Research Society

    Dr Philip J Coates

  32. Autoantibodies and decreased expression of the transcription factor ELF-3 together with increased chemokine pathways support an autoimmune phenotype and altered differentiation in lichen planus located in oral mucosa

    Article • Journal of the European Academy of Dermatology and Venereology, November 2012, Wiley

    Dr Philip J Coates

  33. Radiation-induced bone marrow apoptosis, inflammatory bystander-type signaling and tissue cytotoxicity

    Article • International Journal of Radiation Biology, November 2012, Taylor & Francis

    Dr Philip J Coates

  34. The RNA helicase p68 (DDX5) is selectively required for the induction of p53-dependent p21 expression and cell-cycle arrest after DNA damage

    Article • Oncogene, September 2012, Nature

    Dr Philip J Coates

  35. C-terminal phosphorylation of Hsp70 and Hsp90 regulates alternate binding to co-chaperones CHIP and HOP to determine cellular protein folding/degradation balances

    Article • Oncogene, July 2012, Nature

    Dr Philip J Coates

  36. p63 transcriptionally regulates BNC1, a Pol I and Pol II transcription factor that regulates ribosomal biogenesis and epithelial differentiation

    Article • European Journal of Cancer, June 2012, Elsevier

    Dr Philip J Coates

  37. In VivoInteractions between Ionizing Radiation, Inflammation and Chemical Carcinogens Identified by Increased DNA Damage Responses

    Article • Radiation Research, May 2012, Radiation Research Society

    Dr Philip J Coates

  38. Transcriptional Profiling of Formalin Fixed Paraffin Embedded Tissue: Pitfalls and Recommendations for Identifying Biologically Relevant Changes

    Article • PLoS ONE, April 2012, PLOS

    Dr Philip J Coates

  39. Bystander-Type Effects Mediated by Long-Lived Inflammatory Signaling in Irradiated Bone Marrow

    Article • Radiation Research, March 2012, Radiation Research Society

    Dr Philip J Coates

  40. Phenformin as prophylaxis and therapy in breast cancer xenografts

    Article • British Journal of Cancer, February 2012, Nature

    Dr Philip J Coates

  41. TheIn VivoExpression of Radiation-Induced Chromosomal Instability Has an Inflammatory Mechanism

    Article • Radiation Research, January 2012, Radiation Research Society

    Dr Philip J Coates

  42. Heterogeneity of p53-pathway Protein Expression in Chemosensitive Chronic Lymphocytic Leukemia: A Pilot Study

    Article • Journal of Cancer, January 2012, Ivyspring International Publisher

    Dr Philip J Coates

  43. Subsite-based alterations in miR-21, miR-125b, and miR-203 in squamous cell carcinoma of the oral cavity and correlation to important target proteins

    Article • Journal of Carcinogenesis, January 2012, Medknow

    Dr Philip J Coates

  44. Differences in p63 expression in SCCHN tumours of different sub-sites within the oral cavity

    Article • Oral Oncology, September 2011, Elsevier

    Dr Philip J Coates

  45. Lack of Nontargeted Effects in Murine Bone Marrow after Low-DoseIn VivoX Irradiation

    Article • Radiation Research, March 2011, Radiation Research Society

    Dr Philip J Coates

  46. Effect of Narrow-band Ultraviolet B Phototherapy on p63 and MicroRNA (miR-21 and miR-125b) Expression in Psoriatic Epidermis

    Article • Acta Dermato Venereologica, January 2011, Acta Dermato-Venereologica

    Dr Philip J Coates

  47. The role of P63 in cancer, stem cells and cancer stem cells

    Article • Cellular & Molecular Biology Letters, January 2011, De Gruyter

    Dr Philip J Coates

  48. Comments on “Transcriptional profiling of oral squamous cell carcinoma using formalin-fixed paraffin-embedded samples” by Saleh et al., Oral Oncol 46 (2010) 379–386

    Article • Oral Oncology, December 2010, Elsevier

    Dr Philip J Coates

  49. Differential Contextual Responses of Normal Human Breast Epithelium to Ionizing Radiation in a Mouse Xenograft Model

    Article • Cancer Research, November 2010, American Association for Cancer Research (AACR)

    Dr Philip J Coates

  50. Increased expression of Smad proteins, and in particular Smad3, in oral lichen planus compared to normal oral mucosa

    Article • Journal of Oral Pathology and Medicine, July 2010, Wiley

    Dr Philip J Coates

  51. Radiation-Induced Delayed Bystander-Type Effects Mediated by Hemopoietic Cells

    Article • Radiation Research, June 2010, Radiation Research Society

    Dr Philip J Coates

  52. At last, a predictive and prognostic marker for radiotherapy?

    Article • May 2010, Springer Science + Business Media

    Dr Philip J Coates

  53. Lack of correlation between markers of breast cancer initiating cells

    Article • May 2010, Springer Science + Business Media

    Dr Philip J Coates

  54. The use of a novel ELISA method for detection of antibodies against p63 in sera from patients diagnosed with oral and/or genital and skin lichen planus

    Article • Journal of Oral Pathology and Medicine, April 2010, Wiley

    Dr Philip J Coates

  55. Tubulin α-6 chain is a stably expressed reference gene in archival samples of normal oral tissue and oral squamous cell carcinoma

    Article • Experimental and Therapeutic Medicine, March 2010, Spandidos Publications

    Dr Philip J Coates

  56. p53 and γ radiation in the normal breast

    Article • International Journal of Radiation Biology, November 2009, Taylor & Francis

    Dr Philip J Coates

  57. ΔNp63 isoforms differentially regulate gene expression in squamous cell carcinoma: identification ofCox-2as a novel p63 target

    Article • The Journal of Pathology, August 2009, Wiley

    Dr Philip J Coates

  58. Polymorphisms in p53 and the p53 pathway: roles in cancer susceptibility and response to treatment

    Article • Journal of Cellular and Molecular Medicine, March 2009, Wiley

    Dr Philip J Coates

  59. The annexin-V assay reflects susceptibility to in vitro membrane damage in chronic lymphocytic leukemia and may overestimate cell death

    Article • American Journal of Hematology, March 2009, Wiley

    Dr Philip J Coates

  60. Chromosomal Instability in Unirradiated Hemaopoietic Cells Induced by Macrophages Exposed In vivo to Ionizing Radiation

    Article • Cancer Research, October 2008, American Association for Cancer Research (AACR)

    Dr Philip J Coates

  61. Decreased expression of the p63 related proteins β-catenin, E-cadherin and EGFR in oral lichen planus

    Article • Oral Oncology, July 2008, Elsevier

    Dr Philip J Coates

  62. p63 contributes to cell invasion and migration in squamous cell carcinoma of the head and neck

    Article • Cancer Letters, May 2008, Elsevier

    Dr Philip J Coates

  63. Expression of novel p53 isoforms in oral lichen planus

    Article • Oral Oncology, February 2008, Elsevier

    Dr Philip J Coates

  64. Indirect Macrophage Responses to Ionizing Radiation: Implications for Genotype-Dependent Bystander Signaling

    Article • Cancer Research, January 2008, American Association for Cancer Research (AACR)

    Dr Philip J Coates

  65. Ongoing activation of p53 pathway responses is a long-term consequence of radiation exposure in vivo and associates with altered macrophage activities

    Article • The Journal of Pathology, January 2008, Wiley

    Dr Philip J Coates

  66. The cell type-specific effect of TAp73 isoforms on the cell cycle and apoptosis

    Article • Cellular & Molecular Biology Letters, January 2008, De Gruyter

    Dr Philip J Coates

  67. TRAF4 is potently induced by TAp63 isoforms and localised according to differentiation in SCCHN

    Article • Cancer Biology & Therapy, December 2007, Taylor & Francis

    Dr Philip J Coates

  68. The genetic basis of tissue responses to ionizing radiation

    Article • British Journal of Radiology, September 2007, British Institute of Radiology

    Dr Philip J Coates

  69. Expression of p53 isoforms in squamous cell carcinoma of the head and neck

    Article • European Journal of Cancer, February 2007, Elsevier

    Dr Philip J Coates

  70. Detection of antibodies against p63 and p73 isoforms in sera from patients diagnosed with oral lichen planus

    Article • Journal of Oral Pathology and Medicine, January 2007, Wiley

    Dr Philip J Coates

  71. p53 and Mdm2: not all cells are equal

    Article • The Journal of Pathology, January 2007, Wiley

    Dr Philip J Coates

  72. ΔNp63 isoforms regulate CD44 and keratins 4, 6, 14 and 19 in squamous cell carcinoma of head and neck

    Article • The Journal of Pathology, January 2007, Wiley

    Dr Philip J Coates

  73. Untargeted effects of ionizing radiation: Implications for radiation pathology

    Article • Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, May 2006, Elsevier

    Dr Philip J Coates

  74. Downregulation of TAp63 and Unaffected Levels of p63? Distinguishes Oral Wounds from SCCHN

    Article • Cell Cycle, February 2006, Taylor & Francis

    Dr Philip J Coates

  75. Regulating p73 isoforms in human tumours

    Article • The Journal of Pathology, January 2006, Wiley

    Dr Philip J Coates

  76. Exclusion ofp63as a candidate gene for autosomal-dominant amelogenesis imperfecta

    Article • Acta Odontologica Scandinavica, January 2006, Taylor & Francis

    Dr Philip J Coates

  77. Dysregulation of TAp63 mRNA and Protein Levels in Psoriasis

    Article • Journal of Investigative Dermatology, January 2006, Elsevier

    Dr Philip J Coates

  78. Decreased expression of p63 in oral lichen planus and graft-vs.-host disease associated with oral inflammation

    Article • Journal of Oral Pathology and Medicine, January 2006, Wiley

    Dr Philip J Coates

  79. Endogenous p63 acts as a survival factor for tumour cells of SCCHN origin

    Article • International Journal of Molecular Medicine, December 2005, Spandidos Publications

    Dr Philip J Coates

  80. Chromosomal Instability in Unirradiated Hemopoietic Cells Resulting from a Delayed In vivo Bystander Effect of   Radiation

    Article • Cancer Research, July 2005, American Association for Cancer Research (AACR)

    Dr Philip J Coates

  81. Discriminating functional and non-functional p53 in human tumours by p53 and MDM2 immunohistochemistry

    Article • The Journal of Pathology, January 2005, Wiley

    Dr Philip J Coates

  82. Cell and tissue responses to genotoxic stress

    Article • The Journal of Pathology, January 2005, Wiley

    Dr Philip J Coates

  83. Damaging and protective cell signalling in the untargeted effects of ionizing radiation

    Article • Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, December 2004, Elsevier

    Dr Philip J Coates

  84. Complex p63 mRNA isoform expression patterns in squamous cell carcinoma of the head and neck

    Article • International Journal of Oncology, July 2004, Spandidos Publications

    Dr Philip J Coates

  85. Function and Importance of p63 in Normal Oral Mucosa and Squamous Cell Carcinoma of the Head and Neck

    Article • January 2004, Karger Publishers

    Dr Philip J Coates

  86. Radiation-induced genomic instability and bystander effects: inter-related nontargeted effects of exposure to ionizing radiation

    Article • Oncogene, October 2003, Springer Science + Business Media

    Dr Philip J Coates

  87. Differential Expression of p73?? in Normal Ectocervical Epithelium, Cervical Intraepithelial Neoplasia, and Invasive Squamous Cell Carcinoma

    Article • International Journal of Gynecological Pathology, October 2003, Wolters Kluwer Health

    Dr Philip J Coates

  88. Tissue-specific p53 responses to ionizing radiation and their genetic modification: the key to tissue-specific tumour susceptibility?

    Article • The Journal of Pathology, January 2003, Wiley

    Dr Philip J Coates

  89. The yeast two-hybrid system for identifying protein-protein interactions

    Article • The Journal of Pathology, December 2002, Wiley

    Dr Philip J Coates

  90. Differential expression of p63 isoforms in normal tissues and neoplastic cells

    Article • The Journal of Pathology, September 2002, Wiley

    Dr Philip J Coates

  91. Markers of senescence?

    Article • The Journal of Pathology, January 2002, Wiley

    Dr Philip J Coates

  92. The mitochondrial PHB complex: roles in mitochondrial respiratory complex assembly, ageing and degenerative disease

    Article • Cellular and Molecular Life Sciences, January 2002, Springer Science + Business Media

    Dr Philip J Coates

  93. Inflammatory-type responses after exposure to ionizing radiation in vivo: a mechanism for radiation-induced bystander effects?

    Article • Oncogene, October 2001, Springer Science + Business Media

    Dr Philip J Coates

  94. Induction of endogenous β-galactosidase by ionizing radiation complicates the analysis of p53-LacZ transgenic mice

    Article • Oncogene, October 2001, Springer Science + Business Media

    Dr Philip J Coates

  95. Differential post-translational modification of the tumour suppressor proteins Rb and p53 modulate the rates of radiation-induced apoptosis in vivo

    Article • Oncogene, June 2001, Nature

    Dr Philip J Coates

  96. Mammalian Prohibitin Proteins Respond to Mitochondrial Stress and Decrease during Cellular Senescence

    Article • Experimental Cell Research, May 2001, Elsevier

    Dr Philip J Coates

  97. Characterization of the expression pattern of p63α and δnp63α in benign and malignant oral epithelial lesions

    Article • International Journal of Cancer, August 2000, Wiley

    Dr Philip J Coates

  98. Characterization of the expression pattern of p63α and δnp63α in benign and malignant oral epithelial lesions

    Article • International Journal of Cancer, January 2000, Wiley

    Dr Philip J Coates

  99. Fen1 expression: a novel marker for cell proliferation

    Article • The Journal of Pathology, November 1998, Wiley

    Dr Philip J Coates

  100. Fen1 expression: a novel marker for cell proliferation

    Article • The Journal of Pathology, November 1998, Wiley

    Dr Philip J Coates

  101. THE ASSOCIATION BETWEEN CELL PROLIFERATION AND APOPTOSIS: STUDIES USING THE CELL CYCLE‐ASSOCIATED PROTEINS Ki67 AND DNA POLYMERASE ALPHA

    Article • The Journal of Pathology, January 1996, Wiley

    Dr Philip J Coates

  102. THE ASSOCIATION BETWEEN CELL PROLIFERATION AND APOPTOSIS: STUDIES USING THE CELL CYCLE-ASSOCIATED PROTEINS Ki67 AND DNA POLYMERASE ALPHA

    Article • The Journal of Pathology, January 1996, Wiley

    Dr Philip J Coates

  103. IDENTIFICATION OF THE ANTIGEN RECOGNIZED BY THE MONOCLONAL ANTIBODY BU31 AS LAMINS A AND C

    Article • The Journal of Pathology, January 1996, Wiley

    Dr Philip J Coates

  104. Endocrine cells of the human gastrointestinal tract have no proliferative capacity

    Article • The Histochemical Journal, June 1995, Springer Science + Business Media

    Dr Philip J Coates

  105. Demonstration of DNA damage/repair in individual cells usingin situ end labelling: Association of p53 with sites of DNA damage

    Article • The Journal of Pathology, May 1995, Wiley

    Dr Philip J Coates

  106. Molecular Biology—Changing Our Profession

    Article • Journal of Histotechnology, September 1994, Taylor & Francis

    Dr Philip J Coates

  107. Molecular Methods for the Identification of Apoptosis in Tissues

    Article • Journal of Histotechnology, September 1994, Taylor & Francis

    Dr Philip J Coates

  108. Proliferating cell nuclear antigen expression in non-cycling cells may be induced by growth factors in vivo

    Article • British Journal of Cancer, August 1994, Springer Science + Business Media

    Dr Philip J Coates

  109. Molecular Biology—Changing Our Profession

    Article • Journal of Histotechnology, January 1994, Maney Publishing

    Dr Philip J Coates

  110. Detection of Epstein-Barr virus in Reed-Sternberg cells of Hodgkin's disease arising in children

    Article • Medical and Pediatric Oncology, January 1993, Wiley

    Dr Philip J Coates

  111. Localization of cytochrome P-450 gene expression in normal and diseased human liver byin situ hybridization of wax-embedded archival material

    Article • Hepatology, September 1992, Wiley

    Dr Philip J Coates

  112. Sural nerve biopsies in Guillain-Barre syndrome: Axonal degeneration and macrophage-associated demyelination and absence of cytomegalovirus genome

    Article • Muscle & Nerve, May 1992, Wiley

    Dr Philip J Coates

  113. Characterization of integrin chains in normal and neoplastic human pancreas

    Article • The Journal of Pathology, September 1991, Wiley

    Dr Philip J Coates

  114. Persisten of Epstein-Barr virus in Reed-Sternberg cells throughout the course of Hodgkin's disease

    Article • The Journal of Pathology, August 1991, Wiley

    Dr Philip J Coates

  115. Paraffin Section Molecular Biology: Review of Current Techniques

    Article • Journal of Histotechnology, January 1991, Maney Publishing

    Dr Philip J Coates

  116. In Vitroandin VivoAnalysis of the Processing and Fate of the Peptide Products of the Short Proopiomelanocortin mRNA

    Article • Molecular Endocrinology, November 1990, Endocrine Society

    Dr Philip J Coates

  117. Histotechnology in the 1990s: The Era of Molecular Pathologists?

    Article • Journal of Histotechnology, June 1990, Taylor & Francis

    Dr Philip J Coates

  118. Anal cancer and human papillomaviruses

    Article • Diseases of the Colon & Rectum, December 1989, Wolters Kluwer Health

    Dr Philip J Coates

  119. Rapid technique of DNA-DNA in situ hybridisation on formalin fixed tissue sections using microwave irradiation.

    Article • Journal of Clinical Pathology, August 1987, BMJ

    Dr Philip J Coates

  120. Immunocytochemical study of 18 tumours causing ectopic Cushing's syndrome.

    Article • Journal of Clinical Pathology, September 1986, BMJ

    Dr Philip J Coates

  121. Analysis of Apoptosis in Tissue Sections

    Article • Springer Science + Business Media

    Dr Philip J Coates

  122. Analysis of Apoptosis in Tissue Sections

    Article • Springer Science + Business Media

    Dr Philip J Coates

  123. Detecting and Quantifying Apoptosis in Tissue Sections

    Article • Springer Science + Business Media

    Dr Philip J Coates