All Stories

  1. Connexin Expression in Pituitary Adenomas and the Effects of Overexpression of Connexin 43 in Pituitary Tumor Cell Lines

    Article • Genes, April 2022, MDPI AG

    Paula Soares, MD, PhD José Manuel Lopes

  2. Post-COVID-19 Condition: Where Are We Now?

    Article • Life, March 2022, MDPI AG

    Paula Soares

  3. The ringworm campaign in Portugal, 1940–1970

    Article • February 2022, Oxford University Press (OUP)

    Paula Soares

  4. Performance of the Bethesda System for Reporting Thyroid Cytology in Multi-Institutional Large Cohort of Pediatric Thyroid Nodules: A Detailed Analysis

    Article • Diagnostics, January 2022, MDPI AG

    Paula Soares

  5. The Multifaceted Profile of Thyroid Disease in the Background of DICER1 Germline and Somatic Mutations: Then, Now and Future Perspectives

    Article • Journal of Molecular Pathology, January 2022, MDPI AG

    Paula Soares

  6. <b><i>TERT</i></b> Promoter Mutational Status in the Management of Cutaneous Melanoma: Comparison with Sentinel Lymph Node Biopsy

    Article • Dermatology, September 2021, Karger Publishers

    Paula Soares, MD, PhD José Manuel Lopes

  7. Ubiquitin-Specific Proteases: Players in Cancer Cellular Processes

    Article • Pharmaceuticals, August 2021, MDPI AG

    Paula Soares

  8. LRP1B: A Giant Lost in Cancer Translation

    Article • Pharmaceuticals, August 2021, MDPI AG

    Paula Soares

  9. Combinatorial Therapies to Overcome BRAF/MEK Inhibitors Resistance in Melanoma Cells: An in vitro Study

    Article • Journal of Experimental Pharmacology, May 2021, Taylor & Francis

    Paula Soares, MD, PhD José Manuel Lopes

  10. Genetic Determinants for Prediction of Outcome of Patients with Papillary Thyroid Carcinoma

    Article • Cancers, April 2021, MDPI AG

    Paula Soares

  11. Integrated Metabolomics and Transcriptomics Analysis of Monolayer and Neurospheres from Established Glioblastoma Cell Lines

    Article • Cancers, March 2021, MDPI AG

    Paula Soares

  12. Molecular Pathology of Non-familial Follicular Epithelial–Derived Thyroid Cancer in Adults: From RAS/BRAF-like Tumor Designations to Molecular Risk Stratification

    Article • Endocrine Pathology, March 2021, Springer Science + Business Media

    Paula Soares

  13. Correlation of molecular data with histopathological and clinical features in a series of 66 patients with medullary thyroid carcinoma

    Article • Journal of Endocrinological Investigation, February 2021, Springer Science + Business Media

    Paula Soares

  14. LRP1B Expression as a Putative Predictor of Response to Pegylated Liposomal Doxorubicin Treatment in Ovarian Cancer

    Article • Pathobiology, January 2021, Karger Publishers

    Paula Soares, MD, PhD José Manuel Lopes

  15. Mohs Micrographic Surgery for Head and Neck Nonmelanoma Skin Cancer: An Approach for Ent Surgeons

    Article • Dermatologic Therapy, December 2020, Wiley

    MD, PhD José Manuel Lopes, Paula Soares

  16. S616-p-DRP1 associates with locally invasive behavior of follicular cell-derived thyroid carcinoma

    Article • Endocrine, November 2020, Springer Science + Business Media

    Paula Soares

  17. Clinicopathological Features as Prognostic Predictors of Poor Outcome in Papillary Thyroid Carcinoma

    Article • Cancers, October 2020, MDPI AG

    Paula Soares

  18. Molecular Aspects of Thyroid Calcification

    Article • International Journal of Molecular Sciences, October 2020, MDPI AG

    Paula Soares

  19. Metabolic modulation combined with mTOR pathway inhibition may overcame cutaneous melanoma resistance to MAPK inhibitors treatment

    Article • European Journal of Cancer, October 2020, Elsevier

    Paula Soares, MD, PhD José Manuel Lopes

  20. Clinical Validation of a Urine Test (Uromonitor-V2®) for the Surveillance of Non-Muscle-Invasive Bladder Cancer Patients

    Article • Diagnostics, September 2020, MDPI AG

    Paula Soares

  21. Follicular Lesions with Papillary Nuclear Characteristics: Differences in Chromatin Detected by Computerized Image Analysis

    Article • Archives of Endocrinology and Metabolism, August 2020, Archives of Endocrinology and Metabolism

    Paula Soares

  22. Analyzing the Role of DICER1 Germline Variations in Papillary Thyroid Carcinoma

    Article • European Thyroid Journal, August 2020, Karger Publishers

    Paula Soares

  23. Predictive Biomarkers and Patient Outcome in Platinum-Resistant (PLD-Treated) Ovarian Cancer

    Article • Diagnostics, July 2020, MDPI AG

    MD, PhD José Manuel Lopes, Paula Soares

  24. Comprehensive Assessment of TERT mRNA Expression across a Large Cohort of Benign and Malignant Thyroid Tumours

    Article • Cancers, July 2020, MDPI AG

    Paula Soares

  25. Prognostic Significance of RAS Mutations and P53 Expression in Cutaneous Squamous Cell Carcinomas

    Article • Genes, July 2020, MDPI AG

    MD, PhD José Manuel Lopes, Paula Soares

  26. Erratum to “Gastroenteropancreatic Neuroendocrine Neoplasia Characterization in Portugal: Results from the NETs Study Group of the Portuguese Society of Endocrinology, Diabetes and Metabolism”

    Article • International Journal of Endocrinology, June 2020, Hindawi Publishing Corporation

    Paula Soares, MD, PhD José Manuel Lopes

  27. A 30-Year Long-Term Experience in Appendix Neuroendocrine Neoplasms—Granting a Positive Outcome

    Article • Cancers, May 2020, MDPI AG

    MD, PhD José Manuel Lopes, Paula Soares

  28. Evaluation of the role of mitochondria in the non-targeted effects of ionizing radiation using cybrid cellular models

    Article • Scientific Reports, April 2020, Springer Science + Business Media

    Paula Soares

  29. Reliable blood cancer cells' telomere length evaluation by qPCR

    Article • Cancer Medicine, March 2020, Wiley

    Paula Soares

  30. Head and neck cutaneous basal cell carcinoma: what should the otorhinolaryngology head and neck surgeon care about?

    Article • Acta Otorhinolaryngologica Italica, February 2020, Pacini Editore

    MD, PhD José Manuel Lopes, Paula Soares

  31. Relevant dose of the environmental contaminant, tributyltin, promotes histomorphological changes in the thyroid gland of male rats

    Article • Molecular and Cellular Endocrinology, February 2020, Elsevier

    Paula Soares

  32. TERT Promoter Mutation as a Potential Predictive Biomarker in BCG-Treated Bladder Cancer Patients

    Article • International Journal of Molecular Sciences, January 2020, MDPI AG

    Paula Soares, Professor Luis Lima

  33. Biomarkers for Bladder Cancer Diagnosis and Surveillance: A Comprehensive Review

    Article • Diagnostics, January 2020, MDPI AG

    Paula Soares

  34. Cancer incidence after childhood irradiation for tinea capitis in a Portuguese cohort

    Article • British Journal of Radiology, January 2020, British Institute of Radiology

    Paula Soares

  35. Validation of a Novel, Sensitive, and Specific Urine-Based Test for Recurrence Surveillance of Patients With Non-Muscle-Invasive Bladder Cancer in a Comprehensive Multicenter Study

    Article • Frontiers in Genetics, December 2019, Frontiers

    Paula Soares

  36. Variants of Papillary Thyroid Carcinoma: An Algorithmic Cytomorphology-Based Approach to Cytology Specimens

    Article • Acta Cytologica, October 2019, Karger Publishers

    Professor Fernando Schmitt, Paula Soares

  37. Characterization and antitumor activity of the extracellular carbohydrate polymer from the cyanobacterium Synechocystis ΔsigF mutant

    Article • International Journal of Biological Macromolecules, September 2019, Elsevier

    Paula Soares

  38. Interaction of Genetic Variations inNFE2L2andSELENOSModulates the Risk of Hashimoto's Thyroiditis

    Article • Thyroid, September 2019, Mary Ann Liebert Inc

    Paula Soares, DAVIDE CARVALHO

  39. Gastroenteropancreatic Neuroendocrine Neoplasia Characterization in Portugal: Results from the NETs Study Group of the Portuguese Society of Endocrinology, Diabetes and Metabolism

    Article • International Journal of Endocrinology, August 2019, Hindawi Publishing Corporation

    Ana P Santos, MD, PhD José Manuel Lopes, Paula Soares, BERNARDO DIAS PEREIRA, Fernando Rodrigues

  40. Differential Expression of HMGA1 and HMGA2 in pituitary neuroendocrine tumors

    Article • Molecular and Cellular Endocrinology, June 2019, Elsevier

    Paula Soares

  41. Oncocytic thyroid neoplasms: from histology to molecular biology

    Article • Diagnostic Histopathology, May 2019, Elsevier

    Paula Soares

  42. “The other side of the coin”: understanding noninvasive follicular tumor with papillary-like nuclear features in unifocal and multifocal settings

    Article • Human Pathology, April 2019, Elsevier

    Paula Soares

  43. TERT promoter mutations are associated with poor prognosis in cutaneous squamous cell carcinoma

    Article • Journal of the American Academy of Dermatology, March 2019, Elsevier

    Paula Soares, MD, PhD José Manuel Lopes

  44. Scalp basal cell carcinoma: A different entity?

    Article • Dermatologic Therapy, January 2019, Wiley

    Paula Soares

  45. Selenium and Selenoproteins in Immune Mediated Thyroid Disorders

    Article • Diagnostics, October 2018, MDPI AG

    Paula Soares

  46. The environmental contaminant tributyltin leads to abnormalities in different levels of the hypothalamus-pituitary-thyroid axis in female rats

    Article • Environmental Pollution, October 2018, Elsevier

    Paula Soares

  47. OPNa Overexpression Is Associated with Matrix Calcification in Thyroid Cancer Cell Lines

    Article • International Journal of Molecular Sciences, September 2018, MDPI AG

    Paula Soares

  48. Liposomal therapies in oncology: does one size fit all?

    Article • Cancer Chemotherapy and Pharmacology, August 2018, Springer Science + Business Media

    Paula Soares

  49. Editorial on “The genomic landscape of TERT promoter wildtype-IDH wildtype glioblastoma”

    Article • Translational Cancer Research, August 2018, AME Publishing Company

    Paula Soares

  50. Follicular thyroid lesions: is there a discriminatory potential in the computerized nuclear analysis?

    Article • Endocrine Connections, August 2018, Bioscientifica

    Paula Soares

  51. Unraveling molecular targets of bisphenol A and S in the thyroid gland

    Article • Environmental Science and Pollution Research, July 2018, Springer Science + Business Media

    Jones Graceli, Paula Soares

  52. TERTp mutation is associated with a shorter progression free survival in patients with aggressive histology subtypes of follicular-cell derived thyroid carcinoma

    Article • Endocrine, June 2018, Springer Science + Business Media

    Paula Soares

  53. Melanoma treatment in review

    Article • ImmunoTargets and Therapy, June 2018, Dove Medical Press

    Paula Soares, MD, PhD José Manuel Lopes

  54. Cribriform-morular variant of thyroid carcinoma: a neoplasm with distinctive phenotype associated with the activation of the WNT/β-catenin pathway

    Article • Modern Pathology, May 2018, Springer Science + Business Media

    Paula Soares

  55. mTOR Pathway in Papillary Thyroid Carcinoma: Different Contributions of mTORC1 and mTORC2 Complexes for Tumor Behavior and SLC5A5 mRNA Expression

    Article • International Journal of Molecular Sciences, May 2018, MDPI AG

    Paula Soares

  56. Age-Associated Mortality Risk in Papillary Thyroid Cancer: Does BRAF Make a Real Difference?

    Article • Journal of Clinical Oncology, May 2018, American Society of Clinical Oncology (ASCO)

    Paula Soares

  57. Telomere Maintenance Mechanisms in Cancer

    Article • Genes, May 2018, MDPI AG

    Paula Soares, MD, PhD José Manuel Lopes

  58. Tributyltin and Zebrafish: Swimming in Dangerous Water

    Article • Frontiers in Endocrinology, April 2018, Frontiers

    Paula Soares

  59. Genomic and transcriptomic characterization of the mitochondrial-rich oncocytic phenotype on a thyroid carcinoma background

    Article • Mitochondrion, April 2018, Elsevier

    Valdemar Máximo, Paula Soares

  60. Is Low-Dose Radiation Exposure a Risk Factor for Atherosclerotic Disease?

    Article • Radiation Research, April 2018, Radiation Research Society

    Paula Soares

  61. Multinodular Goiter Progression Toward Malignancy in a Case of DICER1 Syndrome

    Article • American Journal of Clinical Pathology, March 2018, Oxford University Press (OUP)

    Paula Soares

  62. Dynamin-Related Protein 1 at the Crossroads of Cancer

    Article • Genes, February 2018, MDPI AG

    Valdemar Máximo, Paula Soares

  63. CRABP1, C1QL1 and LCN2 are biomarkers of differentiated thyroid carcinoma, and predict extrathyroidal extension

    Article • BMC Cancer, January 2018, Springer Science + Business Media

    Paula Soares

  64. NIS expression in thyroid tumors, relation with prognosis clinicopathological and molecular features

    Article • Endocrine Connections, January 2018, Bioscientifica

    Paula Soares

  65. Frontiers in endocrine disruption: Impacts of organotin on the hypothalamus-pituitary-thyroid axis

    Article • Molecular and Cellular Endocrinology, January 2018, Elsevier

    Paula Soares

  66. Etiopathogenesis of oncocytomas

    Article • Seminars in Cancer Biology, December 2017, Elsevier

    Valdemar Máximo, Paula Soares

  67. Inhibitory Effects of Antagonists of Growth Hormone-Releasing Hormone (GHRH) in Thyroid Cancer

    Article • Hormones and Cancer, September 2017, Springer Science + Business Media

    Paula Soares

  68. Calcitonin receptor expression in medullary thyroid carcinoma

    Article • PeerJ, September 2017, PeerJ

    Paula Soares

  69. Introduction

    Article • July 2017, Springer Science + Business Media

    Paula Soares

  70. Other Rare Tumours and Tumour-Like Lesions

    Article • July 2017, Springer Science + Business Media

    Paula Soares

  71. Rare Familial Tumours

    Article • July 2017, Springer Science + Business Media

    Paula Soares

  72. Rare Follicular Tumours

    Article • July 2017, Springer Science + Business Media

    Paula Soares

  73. Rare Papillary Thyroid Carcinomas

    Article • July 2017, Springer Science + Business Media

    Paula Soares

  74. Small Cell Tumours

    Article • July 2017, Springer Science + Business Media

    Paula Soares

  75. Therapeutic Options

    Article • July 2017, Springer Science + Business Media

    Paula Soares

  76. SDHD promoter mutations are rare events in cutaneous melanomas but SDHD protein expression is downregulated in advanced cutaneous melanoma

    Article • PLoS ONE, June 2017, PLOS

    Paula Soares, MD, PhD José Manuel Lopes

  77. Hobnail Variant of Papillary Thyroid Carcinoma

    Article • The American Journal of Surgical Pathology, June 2017, Wolters Kluwer Health

    Paula Soares

  78. Telomerase and N-Cadherin in Adrenocortical Tumors

    Article • Journal of Cellular Biochemistry, April 2017, Wiley

    Duarte Pignatelli, Valdemar Máximo, Paula Soares, Susana Gomes Gomes Guerreiro

  79. Molecular landscape of metastatic thyroid cancer

    Article • The Journal of Clinical Endocrinology & Metabolism, March 2017, Endocrine Society

    Miguel Melo, Cristina Ribeiro, Paula Soares

  80. The role of ablative treatment in differentiated thyroid cancer management

    Article • Expert Review of Endocrinology & Metabolism, February 2017, Taylor & Francis

    Paula Soares

  81. TERTbiology and function in cancer: beyond immortalisation

    Article • Journal of Molecular Endocrinology, January 2017, Bioscientifica

    Paula Soares

  82. pmTOR is a marker of aggressiveness in papillary thyroid carcinomas

    Article • Surgery, December 2016, Elsevier

    Paula Soares

  83. TERTpromoter mutations: a genetic signature of benign and malignant thyroid tumours occurring in the context of tinea capitis irradiation

    Article • European Journal of Endocrinology, October 2016, Bioscientifica

    Paula Boaventura, Paula Soares

  84. IL6-174 G>C Polymorphism (rs1800795) Association with Late Effects of Low Dose Radiation Exposure in the Portuguese Tinea Capitis Cohort

    Article • PLoS ONE, September 2016, PLOS

    Paula Soares

  85. The Role of ATRX in the Alternative Lengthening of Telomeres (ALT) Phenotype

    Article • Genes, September 2016, MDPI AG

    Paula Soares

  86. Telomerase Activation in Hematological Malignancies

    Article • Genes, September 2016, MDPI AG

    Paula Soares

  87. Erratum: Chromosomal, epigenetic and microRNA-mediated inactivation of LRP1B, a modulator of the extracellular environment of thyroid cancer cells

    Article • Oncogene, August 2016, Springer Science + Business Media

    Paula Soares

  88. TERT promoter mutations in pancreatic endocrine tumours are rare and mainly found in tumours from patients with hereditary syndromes

    Article • Scientific Reports, July 2016, Springer Science + Business Media

    Paula Soares, MD, PhD José Manuel Lopes

  89. Osteopontin-a splice variant is overexpressed in papillary thyroid carcinoma and modulates invasive behavior

    Article • Oncotarget, July 2016, Impact Journals, LLC

    Paula Soares

  90. Molecular profiling, including TERT promoter mutations, of acral lentiginous melanomas

    Article • Melanoma Research, April 2016, Wolters Kluwer Health

    Paula Soares

  91. The prognostic impact of TERT promoter mutations in glioblastomas is modified by the rs2853669 single nucleotide polymorphism

    Article • International Journal of Cancer, March 2016, Wiley

    Valdemar Máximo, Paula Soares, MD, PhD José Manuel Lopes

  92. Telomerase promoter mutations in cancer: beyond immortalization?

    Article • Endocrine Abstracts, February 2016, Bioscientifica

    Paula Soares

  93. Osteopontin expression is correlated with differentiation and good prognosis in medullary thyroid carcinoma

    Article • January 2016, Bioscientifica

    Paula Soares

  94. TERT Promoter Mutations in Soft Tissue Sarcomas

    Article • The International Journal of Biological Markers, January 2016, SAGE Publications

    Dr. Rui M Reis, Paula Soares

  95. Thyroid and Parathyroid Glands

    Article • January 2016, Springer Science + Business Media

    Valdemar Máximo, Paula Soares

  96. Obesity Is Associated With Low NAD+/SIRT Pathway Expression in Adipose Tissue of BMI-Discordant Monozygotic Twins

    Article • The Journal of Clinical Endocrinology & Metabolism, January 2016, Endocrine Society

    Paula Soares, Professor Alfred King Lam

  97. Molecular Markers Involved in Tumorigenesis of Thyroid Carcinoma: Focus on Aggressive Histotypes

    Article • Cytogenetic and Genome Research, January 2016, Karger Publishers

    Paula Soares

  98. Hotspot TERT promoter mutations are rare events in testicular germ cell tumors

    Article • Tumor Biology, November 2015, Springer Science + Business Media

    Paula Soares, Dr. Fatima Baltazar

  99. RAF-1 promotes survival of thyroid cancer cells harboring RET/PTC1 rearrangement independently of ERK activation

    Article • Molecular and Cellular Endocrinology, November 2015, Elsevier

    Paula Soares

  100. ENDOCRINE TUMOURS: Genetic predictors of thyroid cancer outcome

    Article • October 2015, Bioscientifica

    Paula Soares

  101. Overexpression of pyruvate dehydrogenase kinase supports dichloroacetate as a candidate for cutaneous melanoma therapy

    Article • Expert Opinion on Therapeutic Targets, May 2015, Informa Healthcare

    Valdemar Máximo, Paula Soares, MD, PhD José Manuel Lopes

  102. Mitochondrial Dynamics Protein Drp1 Is Overexpressed in Oncocytic Thyroid Tumors and Regulates Cancer Cell Migration

    Article • PLoS ONE, March 2015, PLOS

    Valdemar Máximo, Paula Soares

  103. RE: TERT Promoter Mutation Status as an Independent Prognostic Factor in Cutaneous Melanoma

    Article • JNCI Journal of the National Cancer Institute, March 2015, Oxford University Press (OUP)

    Paula Soares, MD, PhD José Manuel Lopes

  104. Coexistence of TERT Promoter and BRAF Mutations in Papillary Thyroid Carcinoma: Added Value in Patient Prognosis?

    Article • Journal of Clinical Oncology, February 2015, American Society of Clinical Oncology (ASCO)

    Paula Soares

  105. Hashimoto’s Thyroiditis in Adolescents

    Article • US Endocrinology, January 2015, Touch Digital Media, Ltd.

    Paula Soares

  106. Poorly differentiated and undifferentiated thyroid carcinomas

    Article • Turkish Journal of Pathology, January 2015, Federation of Turkish Pathology Societies

    Paula Soares

  107. OXPHOS dysfunction regulates integrin- 1 modifications and enhances cell motility and migration

    Article • Human Molecular Genetics, December 2014, Oxford University Press (OUP)

    Valdemar Máximo, Paula Soares

  108. mTOR activation in medullary thyroid carcinoma with RAS mutation

    Article • European Journal of Endocrinology, November 2014, Bioscientifica

    Paula Soares

  109. Low frequency of TERT promoter mutations in gastrointestinal stromal tumors (GISTs)

    Article • European Journal of Human Genetics, September 2014, Springer Science + Business Media

    Paula Soares, MD, PhD José Manuel Lopes

  110. Differentiated thyroid cancer in patients with resistance to thyroid hormone syndrome. A novel case and a review of the literature

    Article • Frontiers in Molecular Biosciences, September 2014, Frontiers

    Paula Soares

  111. Thyroid and parathyroid tumours in patients submitted to X-ray scalp epilation during the tinea capitis eradication campaign in the North of Portugal (1950–1963)

    Article • Virchows Archiv, August 2014, Springer Science + Business Media

    Paula Soares

  112. Polymorphisms in the TNFA and IL6 Genes Represent Risk Factors for Autoimmune Thyroid Disease

    Article • PLoS ONE, August 2014, PLOS

    Paula Soares

  113. TERT Promoter Mutations in Skin Cancer: The Effects of Sun Exposure and X-Irradiation

    Article • Journal of Investigative Dermatology, August 2014, Elsevier

    Paula Soares, MD, PhD José Manuel Lopes

  114. Telomerase promoter mutations in cancer: an emerging molecular biomarker?

    Article • Virchows Archiv, July 2014, Springer Science + Business Media

    Valdemar Máximo, Paula Soares, MD, PhD José Manuel Lopes

  115. Increased lymphangiogenesis in Riedel thyroiditis (Immunoglobulin G4-related thyroid disease)

    Article • Virchows Archiv, July 2014, Springer Science + Business Media

    Paula Soares

  116. TERT Promoter Mutations Are a Major Indicator of Poor Outcome in Differentiated Thyroid Carcinomas

    Article • The Journal of Clinical Endocrinology & Metabolism, May 2014, Endocrine Society

    Valdemar Máximo, Paula Soares

  117. A Polymorphism in the Promoter Region of the Selenoprotein S Gene (SEPS1) Contributes to Hashimoto's Thyroiditis Susceptibility

    Article • The Journal of Clinical Endocrinology & Metabolism, April 2014, Endocrine Society

    Paula Soares, DAVIDE CARVALHO

  118. C-Cell-Derived Calcitonin-Free Neuroendocrine Carcinoma of the Thyroid

    Article • International Journal of Surgical Pathology, March 2014, SAGE Publications

    Paula Soares

  119. Prognostic biomarkers in thyroid cancer

    Article • Virchows Archiv, February 2014, Springer Science + Business Media

    Paula Soares

  120. Papillary Thyroid Microcarcinoma

    Article • International Journal of Surgical Pathology, January 2014, SAGE Publications

    Paula Soares

  121. Mitochondrial D310 D-Loop instability and histological subtypes in radiation-induced cutaneous basal cell carcinomas

    Article • Journal of Dermatological Science, January 2014, Elsevier

    Valdemar Máximo, Paula Soares, MD, PhD José Manuel Lopes

  122. Primary Squamous Cell Carcinoma of the Thyroid Diagnosed as Anaplastic Carcinoma: Failure in Fine-Needle Aspiration Cytology?

    Article • Case Reports in Pathology, January 2014, Hindawi Publishing Corporation

    Paula Soares

  123. Stimulated Thyroglobulin at Recombinant Human TSH-Aided Ablation Predicts Disease-free Status One Year Later

    Article • The Journal of Clinical Endocrinology & Metabolism, November 2013, Endocrine Society

    Miguel Melo, Paula Soares

  124. A founder SDHB mutation in Portuguese paraganglioma patients

    Article • October 2013, Bioscientifica

    Valdemar Máximo, Paula Soares

  125. Genetic alterations in thyroid tumors from patients irradiated in childhood for tinea capitis treatment

    Article • August 2013, Bioscientifica

    Paula Boaventura, Paula Soares

  126. Nrf2 Is Commonly Activated in Papillary Thyroid Carcinoma, and It Controls Antioxidant Transcriptional Responses and Viability of Cancer Cells

    Article • The Journal of Clinical Endocrinology & Metabolism, August 2013, Endocrine Society

    Paula Soares

  127. Frequency of TERT promoter mutations in human cancers

    Article • Nature Communications, July 2013, Springer Science + Business Media

    Professor Luis Lima, Valdemar Máximo, Paula Soares, MD, PhD José Manuel Lopes

  128. GNAQ and BRAF mutations show differential activation of the mTOR pathway in human transformed cells

    Article • PeerJ, July 2013, PeerJ

    Paula Soares, MD, PhD José Manuel Lopes

  129. Etiopathogenic factors of thyroid cancer

    Article • June 2013, Future Medicine

    Paula Soares

  130. Radiotherapy: radioiodine and external beam irradiation treatment of differentiated thyroid carcinomas

    Article • June 2013, Future Medicine

    Paula Soares

  131. Cribriform-Morular Variant of Papillary Thyroid Carcinoma Displaying Poorly Differentiated Features

    Article • International Journal of Surgical Pathology, January 2013, SAGE Publications

    Paula Soares

  132. CDX2 Expression in Some Variants of Papillary Thyroid Carcinoma

    Article • American Journal of Clinical Pathology, December 2012, Oxford University Press (OUP)

    Paula Soares

  133. MEN1 intragenic deletions may represent the most prevalent somatic event in sporadic primary hyperparathyroidism

    Article • October 2012, Bioscientifica

    Paula Soares

  134. AZD1480 Blocks Growth and Tumorigenesis of RET- Activated Thyroid Cancer Cell Lines

    Article • PLoS ONE, October 2012, PLOS

    Paula Soares

  135. Survey of 548 oncogenic fusion transcripts in thyroid tumors supports the importance of the already established thyroid fusions genes

    Article • Genes Chromosomes and Cancer, September 2012, Wiley

    Paula Soares

  136. Molecular alterations and expression of succinate dehydrogenase complex in wild-type KIT/PDGFRA/BRAF gastrointestinal stromal tumors

    Article • European Journal of Human Genetics, September 2012, Nature

    Valdemar Máximo, Paula Soares, MD, PhD José Manuel Lopes

  137. STAT3 negatively regulates thyroid tumorigenesis

    Article • Proceedings of the National Academy of Sciences, August 2012, Proceedings of the National Academy of Sciences

    Valdemar Máximo, Paula Soares

  138. RET/PTCrearrangement is prevalent in follicular Hürthle cell carcinomas

    Article • Histopathology, July 2012, Wiley

    Valdemar Máximo, Paula Soares

  139. mTOR Pathway Overactivation in BRAF Mutated Papillary Thyroid Carcinoma

    Article • The Journal of Clinical Endocrinology & Metabolism, July 2012, Endocrine Society

    Paula Soares, MD, PhD José Manuel Lopes

  140. Insights into melanoma: targeting the mTOR pathway for therapeutics

    Article • Expert Opinion on Therapeutic Targets, May 2012, Informa Healthcare

    Paula Soares, MD, PhD José Manuel Lopes

  141. TGF-beta/Smad pathway and BRAF mutation play different roles in circumscribed and infiltrative papillary thyroid carcinoma

    Article • Virchows Archiv, April 2012, Springer Science + Business Media

    Paula Soares

  142. The biology and the genetics of Hurthle cell tumors of the thyroid

    Article • April 2012, Bioscientifica

    Valdemar Máximo, Paula Soares

  143. Absence of theBRAFand theGRIM-19Mutations in Oncocytic (Hürthle Cell) Solid Cell Nests of the Thyroid

    Article • American Journal of Clinical Pathology, April 2012, Oxford University Press (OUP)

    Valdemar Máximo, Paula Soares

  144. Head and neck basal cell carcinoma prevalence in individuals submitted to childhood X-ray epilation for tinea capitis treatment

    Article • European Journal of Dermatology, March 2012, John Libbey Eurotext

    Paula Soares

  145. The mTOR Signalling Pathway in Human Cancer

    Article • International Journal of Molecular Sciences, February 2012, MDPI AG

    Paula Soares, MD, PhD José Manuel Lopes

  146. Melanocytic Tumour in a Black Sheep never exposed to Ultraviolet Radiation

    Article • Journal of Comparative Pathology, February 2012, Elsevier

    Paula Soares, MD, PhD José Manuel Lopes

  147. A Clear Cell Renal Cell Carcinoma Inhibiting the Response to Intravitreal Antivascular Endothelial Growth Factor Therapy in Wet Age-Related Macular Disease

    Article • Case Reports in Ophthalmology, January 2012, Karger Publishers

    Paula Soares, MD, PhD José Manuel Lopes

  148. Paraganglioma of seminal vesicle and chromophobe renal cell carcinoma: a case report and literature review

    Article • Sao Paulo Medical Journal, January 2012, FapUNIFESP (SciELO)

    Paula Soares, MD, PhD José Manuel Lopes

  149. A novel germline SDHB mutation in a gastrointestinal stromal tumor patient without bona fide features of the Carney–Stratakis dyad

    Article • Familial Cancer, December 2011, Springer Science + Business Media

    Valdemar Máximo, Paula Soares, MD, PhD José Manuel Lopes

  150. Genetic Alterations in Poorly Differentiated and Undifferentiated Thyroid Carcinomas

    Article • Current Genomics, December 2011, Bentham Science Publishers

    Valdemar Máximo, Paula Soares

  151. Intratumoural lymph vessel density is related to presence of lymph node metastases and separates encapsulated from infiltrative papillary thyroid carcinoma

    Article • Virchows Archiv, November 2011, Springer Science + Business Media

    Paula Soares

  152. Impact of EGFR Genetic Variants on Glioma Risk and Patient Outcome

    Article • Cancer Epidemiology Biomarkers & Prevention, September 2011, American Association for Cancer Research (AACR)

    Paula Soares, MD, PhD José Manuel Lopes

  153. GRIM-19 function in cancer development

    Article • Mitochondrion, September 2011, Elsevier

    Valdemar Máximo, Paula Soares

  154. Orthovanadate-induced cell death in RET/PTC1-harboring cancer cells involves the activation of caspases and altered signaling through PI3K/Akt/mTOR

    Article • Life Sciences, September 2011, Elsevier

    Valdemar Máximo, Paula Soares

  155. Synergistic growth inhibition of cancer cells harboring the RET/PTC1 oncogene by staurosporine and rotenone involves enhanced cell death

    Article • Journal of Biosciences, September 2011, Springer Science + Business Media

    Valdemar Máximo, Paula Soares

  156. The preeminence of growth pattern and invasiveness and the limited influence of BRAF and RAS mutations in the occurrence of papillary thyroid carcinoma lymph node metastases

    Article • Virchows Archiv, July 2011, Springer Science + Business Media

    Paula Soares

  157. In vitro transforming potential, intracellular signaling properties, and sensitivity to a kinase inhibitor (sorafenib) of RET proto-oncogene variants Glu511Lys, Ser649Leu, and Arg886Trp

    Article • Endocrine Related Cancer, May 2011, Bioscientifica

    Paula Soares

  158. Involvement of p53 in cell death following cell cycle arrest and mitotic catastrophe induced by rotenone

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, March 2011, Elsevier

    Valdemar Máximo, Paula Soares

  159. Head and neck lesions in a cohort irradiated in childhood for tinea capitis treatment

    Article • The Lancet Infectious Diseases, March 2011, Elsevier

    Paula Soares

  160. Thyroid hormone as a regulator of tumor induced angiogenesis

    Article • Cancer Letters, February 2011, Elsevier

    Paula Soares

  161. Tumor-in-Tumor of the Thyroid With Basaloid Differentiation: A Lesion With a Solid Cell Nest Neoplastic Component?

    Article • International Journal of Surgical Pathology, January 2011, SAGE Publications

    Paula Soares

  162. Small papillary thyroid cancers—is BRAF of prognostic value?

    Article • Nature Reviews Endocrinology, January 2011, Springer Science + Business Media

    Paula Soares

  163. EBV interferes with the sensitivity of Burkitt lymphoma Akata cells to etoposide

    Article • Journal of Cellular Biochemistry, January 2011, Wiley

    Paula Soares

  164. How to Treat a Signal? Current Basis for RET-Genotype-Oriented Choice of Kinase Inhibitors for the Treatment of Medullary Thyroid Cancer

    Article • Journal of Thyroid Research, January 2011, Hindawi Publishing Corporation

    Paula Soares

  165. mTOR pathway activation in cutaneous melanoma is associated with poorer prognosis characteristics

    Article • Pigment Cell & Melanoma Research, November 2010, Wiley

    Paula Soares, MD, PhD José Manuel Lopes

  166. Chromosomal, epigenetic and microRNA-mediated inactivation of LRP1B, a modulator of the extracellular environment of thyroid cancer cells

    Article • Oncogene, November 2010, Springer Science + Business Media

    Paula Soares

  167. Analysis of GNAQ mutations, proliferation and MAPK pathway activation in uveal melanomas

    Article • British Journal of Ophthalmology, August 2010, BMJ

    Paula Soares, MD, PhD José Manuel Lopes

  168. Multicentre validation study of nucleic acids extraction from FFPE tissues

    Article • Virchows Archiv, July 2010, Springer Science + Business Media

    Paula Soares

  169. Alopecia in women submitted to childhood X-ray epilation for tinea capitis treatment

    Article • British Journal of Dermatology, May 2010, Wiley

    Paula Soares

  170. Review Article: The Familial Counterparts of Follicular Cell—Derived Thyroid Tumors

    Article • International Journal of Surgical Pathology, May 2010, SAGE Publications

    Paula Soares

  171. Identification of a paired box gene 8-peroxisome proliferator-activated receptor gamma (PAX8-PPAR ) rearrangement mosaicism in a patient with an autonomous functioning follicular thyroid carcinoma bearing an activating mutation in the TSH receptor

    Article • Endocrine Related Cancer, April 2010, Bioscientifica

    Paula Soares

  172. Evaluation of the mTOR pathway in ocular (uvea and conjunctiva) melanoma

    Article • Melanoma Research, April 2010, Wolters Kluwer Health

    Paula Soares, MD, PhD José Manuel Lopes

  173. An assessment of the clonality of the components of canine mixed mammary tumours by mitochondrial DNA analysis

    Article • The Veterinary Journal, November 2009, Elsevier

    Valdemar Máximo, Paula Soares

  174. Proliferation and survival molecules implicated in the inhibition of BRAF pathway in thyroid cancer cells harbouring different genetic mutations

    Article • BMC Cancer, October 2009, Springer Science + Business Media

    Paula Soares

  175. A follicular variant of papillary thyroid carcinoma in struma ovarii. Case report with unique molecular alterations

    Article • Histopathology, October 2009, Wiley

    Paula Soares

  176. IsBRAFmutation screening useful for preoperative risk stratification in papillary thyroid cancer?

    Article • Future Oncology, October 2009, Future Medicine

    Paula Soares

  177. BRAFV600Emutation in papillary thyroid carcinoma: a potential target for therapy?

    Article • Expert Review of Endocrinology & Metabolism, September 2009, Taylor & Francis

    Paula Soares

  178. Germline variation of the melanocortin-1 receptor does not explain shared risk for melanoma and thyroid cancer

    Article • Experimental Dermatology, June 2009, Wiley

    Paula Soares

  179. Mitochondria and cancer

    Article • Virchows Archiv, April 2009, Springer Science + Business Media

    Valdemar Máximo, Paula Soares

  180. How molecular pathology is changing and will change the therapeutics of patients with follicular cell-derived thyroid cancer

    Article • Journal of Clinical Pathology, January 2009, BMJ

    Valdemar Máximo, Paula Soares

  181. Cribriform-Morular Variant of Papillary Thyroid Carcinoma

    Article • American Journal of Clinical Pathology, January 2009, Oxford University Press (OUP)

    Paula Soares

  182. Mitochondria and Oncocytomas

    Article • December 2008, Springer Science + Business Media

    Valdemar Máximo, Paula Soares

  183. Cyclic AMP Inhibits the Proliferation of Thyroid Carcinoma Cell Lines through Regulation of CDK4 Phosphorylation

    Article • Molecular Biology of the Cell, November 2008, American Society for Cell Biology (ASCB)

    Paula Soares

  184. Acquisition ofBRAFgene mutations is not a requirement for nodal metastasis of papillary thyroid carcinoma

    Article • Clinical Endocrinology, October 2008, Wiley

    Paula Soares

  185. Follicular thyroid carcinoma with an unusual glomeruloid pattern of growth

    Article • Human Pathology, October 2008, Elsevier

    Paula Soares

  186. Optimization of methods to assess mitochondrial DNA in archival paraffin-embedded tissues from mammary canine tumors

    Article • Jornal Brasileiro de Patologia e Medicina Laboratorial, August 2008, FapUNIFESP (SciELO)

    Valdemar Máximo, Paula Soares

  187. Intragenic Mutations in Thyroid Cancer

    Article • Endocrinology and Metabolism Clinics of North America, June 2008, Elsevier

    Valdemar Máximo, Paula Soares

  188. GRIM-19 in Health and Disease

    Article • Advances in Anatomic Pathology, January 2008, Wolters Kluwer Health

    Valdemar Máximo, Paula Soares

  189. BRAF provides proliferation and survival signals in MSI colorectal carcinoma cells displaying BRAFV600E but not KRAS mutations

    Article • The Journal of Pathology, December 2007, Wiley

    Paula Soares

  190. Loss of heterozygosity at 19p13.2 and 2q21 in tumours from familial clusters of non-medullary thyroid carcinoma

    Article • Familial Cancer, September 2007, Springer Science + Business Media

    Paula Soares

  191. Molecular and Genotypic Characterization of Human Thyroid Follicular Cell Carcinoma–Derived Cell Lines

    Article • Thyroid, August 2007, Mary Ann Liebert Inc

    Valdemar Máximo, Paula Soares

  192. A subset of colorectal carcinomas express c-KIT protein independently of BRAF and/or KRAS activation

    Article • Virchows Archiv, May 2007, Springer Science + Business Media

    Paula Soares, MD, PhD José Manuel Lopes

  193. Thyroid hormone receptor   mutations in the 'hot-spot region' are rare events in thyroid carcinomas

    Article • Journal of Endocrinology, January 2007, Bioscientifica

    Paula Soares

  194. B-RAF mutations in the etiopathogenesis, diagnosis, and prognosis of thyroid carcinomas

    Article • Human Pathology, July 2006, Elsevier

    Paula Soares

  195. The p75 neurotrophin receptor is widely expressed in conventional papillary thyroid carcinoma

    Article • Human Pathology, May 2006, Elsevier

    Paula Soares

  196. Occurrence of the Cys611Tyr mutation and a novel Arg886Trp substitution in the RET proto‐oncogene in multiple endocrine neoplasia type 2 families and sporadic medullary thyroid carcinoma cases originating from the central region of Portugal

    Article • Clinical Endocrinology, April 2006, Wiley

    Dr Maria joão Bugalho, Paula Soares

  197. H-RAS 81 polymorphism is significantly associated with aneuploidy in follicular tumors of the thyroid

    Article • Oncogene, March 2006, Springer Science + Business Media

    Paula Soares

  198. PAX8-PPARγ Rearrangement Is Frequently Detected in the Follicular Variant of Papillary Thyroid Carcinoma

    Article • The Journal of Clinical Endocrinology & Metabolism, January 2006, Endocrine Society

    Paula Soares

  199. Diagnostic Criteria in Well-Differentiated Thyroid Carcinomas

    Article • Endocrine Pathology, January 2006, Springer Science + Business Media

    Paula Soares

  200. Reply to: Low prevalence of BRAF mutations in radiation-induced thyroid tumors in contrast to sporadic papillary carcinomas

    Article • Cancer Letters, December 2005, Elsevier

    Valdemar Máximo, Paula Soares

  201. Mitochondrial D-Loop instability in thyroid tumours is not a marker of malignancy

    Article • Mitochondrion, October 2005, Elsevier

    Valdemar Máximo, Paula Soares

  202. Molecular pathology of well-differentiated thyroid carcinomas

    Article • Virchows Archiv, September 2005, Springer Science + Business Media

    Valdemar Máximo, Paula Soares

  203. A new BRAF gene mutation detected in a case of a solid variant of papillary thyroid carcinoma

    Article • Human Pathology, June 2005, Elsevier

    Paula Soares

  204. Type and prevalence of BRAF mutations are closely associated with papillary thyroid carcinoma histotype and patients’ age but not with tumour aggressiveness

    Article • Virchows Archiv, May 2005, Springer Science + Business Media

    Valdemar Máximo, Paula Soares

  205. A stem cell role for thyroid solid cell nests

    Article • Human Pathology, May 2005, Elsevier

    Paula Soares

  206. Somatic and germline mutation in GRIM-19, a dual function gene involved in mitochondrial metabolism and cell death, is linked to mitochondrion-rich (Hürthle cell) tumours of the thyroid

    Article • British Journal of Cancer, April 2005, Nature

    Valdemar Máximo, Paula Soares

  207. Cystic Tumor of the Atrioventricular Node of the Heart Appears to Be the Heart Equivalent of the Solid Cell Nests (Ultimobranchial Rests) of the Thyroid

    Article • American Journal of Clinical Pathology, March 2005, Oxford University Press (OUP)

    Paula Soares

  208. Adenomas and follicular carcinomas of the thyroid display two major patterns of chromosomal changes

    Article • The Journal of Pathology, January 2005, Wiley

    Paula Soares

  209. Mutation analysis of B-RAF gene in human gliomas

    Article • Acta Neuropathologica, November 2004, Springer Science + Business Media

    Paula Soares, MD, PhD José Manuel Lopes

  210. BRAFMutations Are Not a Major Event in Post-Chernobyl Childhood Thyroid Carcinomas

    Article • The Journal of Clinical Endocrinology & Metabolism, September 2004, Endocrine Society

    Valdemar Máximo, Paula Soares

  211. Telomerase expression and proliferative activity suggest a stem cell role for thyroid solid cell nests

    Article • Modern Pathology, March 2004, Springer Science + Business Media

    Paula Soares

  212. Core I gene is overexpressed in Hürthle and non-Hürthle cell microfollicular adenomas and follicular carcinomas of the thyroid

    Article • BMC Cancer, March 2004, Springer Science + Business Media

    Valdemar Máximo, Paula Soares

  213. BRAF mutations are associated with some histological types of papillary thyroid carcinoma

    Article • The Journal of Pathology, January 2004, Wiley

    Valdemar Máximo, Paula Soares

  214. Germline Succinate Dehydrogenase Subunit D Mutation Segregating with Familial Non-RET C Cell Hyperplasia

    Article • The Journal of Clinical Endocrinology & Metabolism, October 2003, Endocrine Society

    Valdemar Máximo, Paula Soares

  215. BRAF mutations and RET/PTC rearrangements are alternative events in the etiopathogenesis of PTC

    Article • Oncogene, July 2003, Nature

    Valdemar Máximo, Paula Soares

  216. E-cadherin loss rather than beta-catenin alterations is a common feature of poorly differentiated thyroid carcinomas

    Article • Histopathology, June 2003, Wiley

    Paula Soares

  217. Immunohistochemical study of heat shock proteins 27, 60 and 70 in the normal human adrenal and in adrenal tumors with suppressed ACTH production

    Article • Microscopy Research and Technique, May 2003, Wiley

    Paula Soares

  218. Vascular Invasion in Thyroid and Gastric Carcinomas

    Article • Ultrastructural Pathology, January 2003, Taylor & Francis

    Paula Soares

  219. p63 Expression in Solid Cell Nests of the Thyroid: Further Evidence for a Stem Cell Origin

    Article • Modern Pathology, January 2003, Springer Science + Business Media

    Paula Soares

  220. Mucoepidermoid carcinoma of the thyroid: a tumour histotype characterised by P-cadherin neoexpression and marked abnormalities of E-cadherin/catenins complex

    Article • Virchows Archiv, May 2002, Springer Science + Business Media

    Valdemar Máximo, Paula Soares

  221. Diffuse (or multinodular) follicular variant of papillary thyroid carcinoma: a clinicopathologic and immunohistochemical analysis of ten cases of an aggressive form of differentiated thyroid carcinoma

    Article • Virchows Archiv, December 2001, Springer Science + Business Media

    Paula Soares

  222. Microsatellite instability, mitochondrial DNA large deletions, and mitochondrial DNA mutations in gastric carcinoma

    Article • Genes Chromosomes and Cancer, August 2001, Wiley

    Valdemar Máximo, Paula Soares

  223. Abnormalities of the E-cadherin/catenin adhesion complex in classical papillary thyroid carcinoma and in its diffuse sclerosing variant

    Article • The Journal of Pathology, May 2001, Wiley

    Valdemar Máximo, Paula Soares

  224. E-cadherin gene (CDH1) promoter methylation as the second hit in sporadic diffuse gastric carcinoma

    Article • Oncogene, March 2001, Springer Science + Business Media

    Paula Soares

  225. Fetal adenomas and minimally invasive follicular carcinomas of the thyroid frequently display a triploid or near triploid DNA pattern

    Article • Virchows Archiv, February 2001, Springer Science + Business Media

    Paula Soares

  226. Extended structural variation of a pentanucleotide repeat in the GSTP1 gene: characterisation in a normal population and in thyroid and gastric tumours

    Article • European Journal of Human Genetics, July 2000, Springer Science + Business Media

    Paula Soares

  227. Comments on: Mutations in Mitochondrial Control Region DNA in Gastric Tumours of Japanese Patients, Tamura, et al. Eur J Cancer 1999, 35, 316–319

    Article • European Journal of Cancer, September 1999, Elsevier

    Valdemar Máximo, Paula Soares

  228. Sporadicret-rearranged papillary carcinoma of the thyroid: a subset of slow growing, less aggressive thyroid neoplasms?

    Article • The Journal of Pathology, May 1998, Wiley

    Paula Soares

  229. Benign and malignant thyroid lesions show instability at microsatellite loci

    Article • European Journal of Cancer, February 1997, Elsevier

    Paula Soares

  230. E-cadherin gene alterations are rare events in thyroid tumors

    Article • International Journal of Cancer, January 1997, Wiley

    Paula Soares

  231. Chromosome analysis of 73 thyroid neoplasms

    Article • Cancer Genetics and Cytogenetics, October 1994, Elsevier

    Paula Soares

  232. Correspondence

    Article • Cancer, June 1994, Wiley

    Paula Soares

  233. Thyroid nodular hyperplasia

    Article • Cancer Genetics and Cytogenetics, August 1993, Elsevier

    Paula Soares

  234. Cytogenetic findings in eleven gastric carcinomas

    Article • Cancer Genetics and Cytogenetics, July 1993, Elsevier

    Paula Soares

  235. Cytogenetic findings in 18 follicular thyroid adenomas

    Article • Cancer Genetics and Cytogenetics, May 1993, Elsevier

    Paula Soares

  236. Clonal cytogenetic abnormalities and telomeric associations in a fibroxanthoma of the stomach

    Article • Genes Chromosomes and Cancer, November 1992, Wiley

    Paula Soares

  237. Loss of Y chromosome in gastric carcinoma

    Article • Cancer Genetics and Cytogenetics, July 1992, Elsevier

    Paula Soares

  238. Signet Ring Cell Carcinoma of the Stomach: A Morphometric, Ultrastructural, and DNA Cytometric Study

    Article • Ultrastructural Pathology, January 1992, Taylor & Francis

    Paula Soares