All Stories

  1. One species, many faces: The underappreciated importance of strain diversity
  2. The intricate link between iron, mitochondria and azoles in Candida species
  3. Oteseconazole: a long-awaited diversification of the antifungal arsenal to manage recurrent vulvovaginal candidiasis (RVVC)
  4. Can we microbe-manage our vitamin acquisition for better health?
  5. The Cdc25 and Ras1 Proteins of Candida albicans Influence Epithelial Toxicity in a Niche-Specific Way
  6. Sources of Antifungal Drugs
  7. Oteseconazole (VIVOJA) for prevention of recurrent vulvovaginal candidiasis
  8. Differential sensing by theC. albicansGpr1 receptor results in morphogenesis, β-glucan masking and survival in macrophages
  9. Antibiofilm Combinatory Strategy: Moxifloxacin-Loaded Nanosystems and Encapsulated N-Acetyl-L-Cysteine
  10. In Vitro Assessment of Azole and Amphotericin B Susceptibilities of Malassezia spp. Isolated from Healthy and Lesioned Skin
  11. Microwave Interferometric Cytometry for Signal Analysis of Single Yeast Cells
  12. Two trehalase isoforms, produced from a single transcript, regulate drought stress tolerance in Arabidopsis thaliana
  13. Interesting antifungal drug targets in the central metabolism of Candida albicans
  14. A Complex Microbial Interplay Underlies Recurrent Vulvovaginal Candidiasis Pathobiology
  15. Diagnostic Allele-Specific PCR for the Identification of Candida auris Clades
  16. Probe-based intravital microscopy: filling the gap between in vivo imaging and tissue sample microscopy in basic research and clinical applications
  17. Investigating the Antifungal Mechanism of Action of Polygodial by Phenotypic Screening in Saccharomyces cerevisiae
  18. Photochromic Fluorophores Enable Imaging of Lowly Expressed Proteins in the Autofluorescent Fungus Candida albicans
  19. Genome-Wide Analysis of Experimentally Evolved Candida auris Reveals Multiple Novel Mechanisms of Multidrug Resistance
  20. Photochromic fluorophores enable imaging of lowly-expressed proteins in the autofluorescent fungus Candida albicans
  21. Fluorescent toys ‘n’ tools lighting the way in fungal research
  22. Microbial Interkingdom Biofilms and the Quest for Novel Therapeutic Strategies
  23. Inhibitory Activity of Essential Oils against Vibrio campbellii and Vibrio parahaemolyticus
  24. Amphotericin B and Other Polyenes—Discovery, Clinical Use, Mode of Action and Drug Resistance
  25. Genome-wide analysis of experimentally evolvedCandida aurisreveals multiple novel mechanisms of multidrug-resistance
  26. Molecular Elucidation of Riboflavin Production and Regulation in Candida albicans, toward a Novel Antifungal Drug Target
  27. Sugar Phosphorylation Controls Carbon Source Utilization and Virulence of Candida albicans
  28. Adapting to survive: How Candida overcomes host-imposed constraints during human colonization
  29. Presenting a codon-optimized palette of fluorescent proteins for use in Candida albicans
  30. Let’s shine a light on fungal infections: A noninvasive imaging toolbox
  31. Striking essential oil: tapping into a largely unexplored source for drug discovery
  32. Three-Dimensional Visualization of APEX2-Tagged Erg11 in Saccharomyces cerevisiae Using Focused Ion Beam Scanning Electron Microscopy
  33. Transcriptional responses of Candida glabrata biofilm cells to fluconazole are modulated by the carbon source
  34. Candida albicans and Staphylococcus Species: A Threatening Twosome
  35. Impact of nanosystems in Staphylococcus aureus biofilms treatment
  36. Mitogen-Activated Protein Kinase Cross-Talk Interaction Modulates the Production of Melanins in Aspergillus fumigatus
  37. Inhibition of Vesicular Transport Influences Fungal Susceptibility to Fluconazole
  38. Sugar Sensing and Signaling in Candida albicans and Candida glabrata
  39. Candidalysin Crucially Contributes to Nlrp3 Inflammasome Activation by Candida albicans Hyphae
  40. Monitoring of Fluconazole and Caspofungin Activity against In Vivo Candida glabrata Biofilms by Bioluminescence Imaging
  41. Fungal persister cells: The basis for recalcitrant infections?
  42. A High-ThroughputCandida albicansTwo-Hybrid System
  43. Fire blight host-pathogen interaction: proteome profiles of Erwinia amylovora infecting apple rootstocks
  44. Anidulafungin increases the antibacterial activity of tigecycline in polymicrobial Candida albicans/Staphylococcus aureus biofilms on intraperitoneally implanted foreign bodies
  45. Bioluminescence imaging increases in vivo screening efficiency for antifungal activity against device-associated Candida albicans biofilms
  46. Introducing fluorescence resonance energy transfer-based biosensors for the analysis of cAMP-PKA signalling in the fungal pathogen Candida glabrata
  47. Antifungal Activity and Synergism with Azoles of Polish Propolis
  48. Candida glabrata’s Genome Plasticity Confers a Unique Pattern of Expressed Cell Wall Proteins
  49. Antifungal Activity and Synergism with Azoles of Polish Propolis
  50. Fungal G-protein-coupled receptors: mediators of pathogenesis and targets for disease control
  51. Essential oils and their components are a class of antifungals with potent vapour-phase-mediated anti-Candida activity
  52. Methionine is required for cAMP-PKA mediated morphogenesis and virulence of Candida albicans
  53. Antifungal Activity of Oleylphosphocholine on In Vitro and In Vivo Candida albicans Biofilms
  54. Comparison of genome engineering using the CRISPR-Cas9 system in C. glabrata wild-type and lig4 strains
  55. Modulation of Staphylococcus aureus Response to Antimicrobials by the Candida albicans Quorum Sensing Molecule Farnesol
  56. Nutrient Sensing at the Plasma Membrane of Fungal Cells
  57. A Bimolecular Fluorescence Complementation Tool for Identification of Protein-Protein Interactions in Candida albicans
  58. Mitochondrial Cochaperone Mge1 Is Involved in Regulating Susceptibility to Fluconazole in Saccharomyces cerevisiae and Candida Species
  59. Be careful for false positive results caused by volatiles!
  60. A signaling cascade linking CO2 sensing and lipid signaling in fungi
  61. Fungal–Bacterial Interactions: In Health and Disease
  62. Characterization of the Candida albicans Amino Acid Permease Family: Gap2 Is the Only General Amino Acid Permease and Gap4 Is an S-Adenosylmethionine (SAM) Transporter Required for SAM-Induced Morphogenesis
  63. The antifungal caspofungin increases fluoroquinolone activity against Staphylococcus aureus biofilms by inhibiting N-acetylglucosamine transferase
  64. Commensal Protection ofStaphylococcus aureusagainst Antimicrobials byCandida albicansBiofilm Matrix
  65. Transcription Factor Arabidopsis Activating Factor1 Integrates Carbon Starvation Responses with Trehalose Metabolism
  66. Deletion of the DNA Ligase IV Gene in Candida glabrata Significantly Increases Gene-Targeting Efficiency
  67. Trehalose-6-phosphate synthase 1 is not the only active TPS in Arabidopsis thaliana
  68. Candida albicans Biofilm Development on Medically-relevant Foreign Bodies in a Mouse Subcutaneous Model Followed by Bioluminescence Imaging
  69. Force Nanoscopy of Hydrophobic Interactions in the Fungal Pathogen Candida glabrata
  70. Clinical Implications of Oral Candidiasis: Host Tissue Damage and Disseminated Bacterial Disease
  71. In vivo Candida glabrata biofilm development on foreign bodies in a rat subcutaneous model
  72. Oral Administration of the Broad-Spectrum Antibiofilm Compound Toremifene Inhibits Candida albicans and Staphylococcus aureus Biofilm FormationIn Vivo
  73. Functional screening of a cDNA library from the desiccation-tolerant plant Selaginella lepidophylla in yeast mutants identifies trehalose biosynthesis genes of plant and microbial origin
  74. Duplication of a promiscuous transcription factor drives the emergence of a new regulatory network
  75. Ascorbic Acid Inhibition of Candida albicans Hsp90-Mediated Morphogenesis Occurs via the Transcriptional Regulator Upc2
  76. The desiccation tolerant secrets of Selaginella lepidophylla: What we have learned so far?
  77. Molecular mechanisms of antimicrobial tolerance and resistance in bacterial and fungal biofilms
  78. Trehalose metabolism in plants
  79. Fine tuning of trehalose biosynthesis and hydrolysis as novel tools for the generation of abiotic stress tolerant plants
  80. Cool Tools 1: Development and Application of a Candida albicans Two-Hybrid System
  81. Microbial biofilms - the coming of age of a research field
  82. Candida Biofilms and the Host: Models and New Concepts for Eradication
  83. Microbial cell surface proteins and secreted metabolites involved in multispecies biofilms
  84. Mammalian ribosomal and chaperone protein RPS3A counteracts α-synuclein aggregation and toxicity in a yeast model system
  85. Quantifying the Forces Driving Cell–Cell Adhesion in a Fungal Pathogen
  86. Bioluminescence Imaging of Fungal Biofilm Development in Live Animals
  87. Towards non-invasive monitoring of pathogen-host interactions duringCandida albicansbiofilm formation usingin vivobioluminescence
  88. Recent insights into Candida albicans biofilm resistance mechanisms
  89. Relevance of Trehalose in Pathogenicity: Some General Rules, Yet Many Exceptions
  90. Metabolic engineering of Kluyveromyces lactis for L-ascorbic acid (vitamin C) biosynthesis
  91. Redundant and non-redundant roles of the trehalose-6-phosphate phosphatases in leaf growth, root hair specification and energy-responses in Arabidopsis
  92. Activities of Systemically Administered Echinocandins againstIn VivoMature Candida albicans Biofilms Developed in a Rat Subcutaneous Model
  93. Overexpression of the Trehalase Gene AtTRE1 Leads to Increased Drought Stress Tolerance in Arabidopsis and Is Involved in Abscisic Acid-Induced Stomatal Closure
  94. Single-cell force spectroscopy of the medically important Staphylococcus epidermidis–Candida albicans interaction
  95. Oriented Polar Snakes for Phase Contrast Cell Images Segmentation
  96. Single-Molecule Imaging and Functional Analysis of Als Adhesins and Mannans during Candida albicans Morphogenesis
  97. The Nonsteroidal Antiinflammatory Drug Diclofenac Potentiates the In Vivo Activity of Caspofungin Against Candida albicans Biofilms
  98. Loss-of-function mutations in HINT1 cause axonal neuropathy with neuromyotonia
  99. Tight Control of Trehalose Content Is Required for Efficient Heat-induced Cell Elongation in Candida albicans
  100. Expansive Evolution of the TREHALOSE-6-PHOSPHATE PHOSPHATASE Gene Family in Arabidopsis
  101. Diversity in Genetic In Vivo Methods for Protein-Protein Interaction Studies: from the Yeast Two-Hybrid System to the Mammalian Split-Luciferase System
  102. The Heat-Induced Molecular Disaggregase Hsp104 of Candida albicans Plays a Role in Biofilm Formation and Pathogenicity in a Worm Infection Model
  103. Potent Synergistic Effect of Doxycycline with Fluconazole against Candida albicans Is Mediated by Interference with Iron Homeostasis
  104. Transcription factor Efg1 contributes to the tolerance of Candida albicans biofilms against antifungal agents in vitro and in vivo
  105. Heterozygous missense mutations in SMARCA2 cause Nicolaides-Baraitser syndrome
  106. CandidaBiofilms and the Host: Models and New Concepts for Eradication
  107. The Candida albicans GAP Gene Family Encodes Permeases Involved in General and Specific Amino Acid Uptake and Sensing
  108. Detailed comparison of Candida albicans and Candida glabrata biofilms under different conditions and their susceptibility to caspofungin and anidulafungin
  109. How Do Sugars Regulate Plant Growth?
  110. Mutations in the SPTLC2 Subunit of Serine Palmitoyltransferase Cause Hereditary Sensory and Autonomic Neuropathy Type I
  111. Candida albicans Pde1p and Gpa2p comprise a regulatory module mediating agonist-induced cAMP signalling and environmental adaptation
  112. A CUG codon adapted two-hybrid system for the pathogenic fungus Candida albicans
  113. In Vivo Efficacy of Anidulafungin against Mature Candida albicans Biofilms in a Novel Rat Model of Catheter-Associated Candidiasis
  114. Effect of antifungals on itraconazole resistant Candida glabrata
  115. Real-time PCR expression profiling of genes encoding potential virulence factors in Candida albicans biofilms: identification of model-dependent and -independent gene expression
  116. A Single Active Trehalose-6-P Synthase (TPS) and a Family of Putative Regulatory TPS-Like Proteins in Arabidopsis
  117. Stress Tolerance of the <i>Saccharomyces cerevisiae</i> Adenylate Cyclase <i>fil1</i> (<i>CYR1</i><sup>lys1682</sup>) Mutant Depends on Hsp26
  118. Candida albicans biofilm formation in a new in vivo rat model
  119. Nutrient sensing G protein-coupled receptors: interesting targets for antifungals?
  120. The Cytophaga hutchinsonii ChTPSP: First Characterized Bifunctional TPS-TPP Protein as Putative Ancestor of All Eukaryotic Trehalose Biosynthesis Proteins
  121. Small G proteins in peroxisome biogenesis: the potential involvement of ADP-ribosylation factor 6
  122. Extensive expression regulation and lack of heterologous enzymatic activity of the Class II trehalose metabolism proteins from Arabidopsis thaliana
  123. Dominant mutations in the tyrosyl-tRNA synthetase gene recapitulate in Drosophila features of human Charcot–Marie–Tooth neuropathy
  124. Nutrient sensing G protein-coupled receptors: interesting targets for antifungals?
  125. Extracting expression modules from perturbational gene expression compendia
  126. Flavour formation in fungi: characterisation of KlAtf, the Kluyveromyces lactis orthologue of the Saccharomyces cerevisiae alcohol acetyltransferases Atf1 and Atf2
  127. Identification of Hexose Transporter-Like Sensor HXS1 and Functional Hexose Transporter HXT1 in the Methylotrophic Yeast Hansenula polymorpha
  128. Combined Inactivation of the Candida albicans GPR1 and TPS2 Genes Results in Avirulence in a Mouse Model for Systemic Infection
  129. Parameters Affecting Ethyl Ester Production by Saccharomyces cerevisiae during Fermentation
  130. Trehalose-6-P synthase AtTPS1 high molecular weight complexes in yeast and Arabidopsis
  131. A bifunctional TPS–TPP enzyme from yeast confers tolerance to multiple and extreme abiotic-stress conditions in transgenic Arabidopsis
  132. Environmental Sensing and Signal Transduction Pathways Regulating Morphopathogenic Determinants of Candida albicans
  133. Improved drought tolerance without undesired side effects in transgenic plants producing trehalose
  134. Attachment ofMAL32-encoded maltase on the outside of yeast cells improves maltotriose utilization
  135. 2.306 A yeast-based screening system for mouse brain proteins that modify the toxicity of alpha-synuclein
  136. 2.308 Characterization of the expression of alpha-synuclein and suppressor/enhancer proteins in Saccharomyces cerevisiae
  137. Isolation and Characterization of Brewer's Yeast Variants with Improved Fermentation Performance under High-Gravity Conditions
  138. Immunogold localization of trehalose-6-phosphate synthase in leaf segments of wild-type and transgenic tobacco plants expressing the AtTPS1 gene from Arabidopsis thaliana
  139. ABI4 mediates the effects of exogenous trehalose on Arabidopsis growth and starch breakdown
  140. P3–158: A novel locus for autosomal dominant dementia with Lewy bodies on chromosome 2Q35–36
  141. Why do microorganisms have aquaporins?
  142. Trehalose-6-phosphate synthase as an intrinsic selection marker for plant transformation
  143. Disrupted function and axonal distribution of mutant tyrosyl-tRNA synthetase in dominant intermediate Charcot-Marie-Tooth neuropathy
  144. Physiological and Molecular Responses of Yeasts to the Environment
  145. Transformation of tobacco with an Arabidopsis thaliana gene involved in trehalose biosynthesis increases tolerance to several abiotic stresses
  146. Aquaporin Expression and Freeze Tolerance in Candida albicans
  147. Nutrient sensing systems for rapid activation of the protein kinase A pathway in yeast
  148. Carbon source induced yeast-to-hypha transition in Candida albicans is dependent on the presence of amino acids and on the G-protein-coupled receptor Gpr1: Figure 1
  149. Heterologous Aquaporin (<i>AQY2–1</i>) Expression Strongly Enhances Freeze Tolerance of <i>Schizosaccharomyces pombe</i>
  150. Glucose and Sucrose Act as Agonist and Mannose as Antagonist Ligands of the G Protein-Coupled Receptor Gpr1 in the Yeast Saccharomyces cerevisiae
  151. Glucose and sucrose: hazardous fast-food for industrial yeast?
  152. Aquaporin-Mediated Improvement of Freeze Tolerance of Saccharomyces cerevisiae Is Restricted to Rapid Freezing Conditions
  153. Trehalose Metabolism: Enzymatic Pathways and Physiological Functions
  154. The high general stress resistance of the Saccharomyces cerevisiae fil1 adenylate cyclase mutant (Cyr1Lys1682) is only partially dependent on trehalose, Hsp104 and overexpression of Msn2/4‐regulated genes
  155. Progress in functional genomics approaches to antifungal drug target discovery
  156. Uncoupling of the glucose growth defect and the deregulation of glycolysis in Saccharomyces cerevisiae tps1 mutants expressing trehalose-6-phosphate-insensitive hexokinase from Schizosaccharomyces pombe
  157. Activation state of protein kinase A as measured in permeabilised Saccharomyces cerevisiae cells correlates with PKA-controlled phenotypes in vivo
  158. Corrigendum to “Activation state of protein kinase A as measured in permeabilised Saccharomyces cerevisiae cells correlates with PKA-controlled phenotypes in vivo” [FEMS Yeast Research (2003) this issue]★
  159. Determinants of Freeze Tolerance in Microorganisms, Physiological Importance, and Biotechnological Applications
  160. Aquaporin Expression Correlates with Freeze Tolerance in Baker's Yeast, and Overexpression Improves Freeze Tolerance in Industrial Strains
  161. Isolation and Characterization of a Freeze-Tolerant Diploid Derivative of an Industrial Baker's Yeast Strain and Its Use in Frozen Doughs
  162. Truncation of Arabidopsis thaliana and Selaginella lepidophylla trehalose-6-phosphate synthase unlocks high catalytic activity and supports high trehalose levels on expression in yeast
  163. Disruption of the Candida albicans TPS2 Gene Encoding Trehalose-6-Phosphate Phosphatase Decreases Infectivity without Affecting Hypha Formation
  164. Functional Genomics Approaches for the Identification and Validation of Antifungal Drug Targets
  165. An unexpected plethora of trehalose biosynthesis genes in Arabidopsis thaliana
  166. Identification of two related genes responsible for improved freeze-resistance in baker's yeast
  167. Expression of Escherichia coli otsA in a Saccharomyces cerevisiae tps1 mutant restores trehalose 6-phosphate levels and partly restores growth and fermentation with glucose and control of glucose influx into glycolysis
  168. Nutrient-induced signal transduction through the protein kinase A pathway and its role in the control of metabolism, stress resistance, and growth in yeast
  169. A specific mutation in Saccharomyces cerevisiae adenylate cyclase, Cyr1K1876M, eliminates glucose- and acidification-induced cAMP signalling and delays glucose-induced loss of stress resistance
  170. Characterization of a new set of mutants deficient in fermentation-induced loss of stress resistance for use in frozen dough applications
  171. Identification of genes responsible for improved cryoresistance in fermenting yeast cells
  172. Analysis and modification of trehalose 6-phosphate levels in the yeast Saccharomyces cerevisiae with the use of Bacillus subtilis phosphotrehalase
  173. Deletion ofSFI1, a novel suppressor of partial Ras-cAMP pathway deficiency in the yeastSaccharomyces cerevisiae, causes G2 arrest
  174. A mutation in Saccharomyces cerevisiae adenylate cyclase, Cyr1K1876M, specifically affects glucose- and acidification-induced cAMP signalling and not the basal cAMP level
  175. A Saccharomyces cerevisiae G‐protein coupled receptor, Gpr1, is specifically required for glucose activation of the cAMP pathway during the transition to growth on glucose
  176. The PDE1-encoded Low-Affinity Phosphodiesterase in the Yeast Saccharomyces cerevisiae Has a Specific Function in Controlling Agonist-induced cAMP Signaling
  177. Molecular cloning of the neutral trehalase gene from Kluyveromyces lactis and the distinction between neutral and acid trehalases
  178. Regulation of genes encoding subunits of the trehalose synthase complex inSaccharomyces cerevisiae: novel variations of STRE-mediated transcription control?
  179. Regulation of genes encoding subunits of the trehalose synthase complex in
  180. The byp1-3 allele of the Saccharomyces cerevisiae GGS1/TPS1 gene and its multi-copy suppressor tRNAGLN (CAG): Ggs1/Tps1 protein levels restraining growth on fermentable sugars and trehalose accumulation
  181. A Fos-Jun element in the first intron of an α2u-globulin gene
  182. Multiple binding sites for nuclear factors in the 5′-upstream region of two α2u-globulin genes: Implications for hormone-regulated and tissue-specific control
  183. Molecular cloning of a gene involved in glucose sensing in the yeast Saccharomyces cerevisiae
  184. Interaction of the 90-kDa heat shock protein with native and in vitro translated androgen receptor and receptor fragments
  185. Tissue-Specific Expression and Androgen Regulation of Different Genes Encoding Rat Prostatic 22-Kilodalton Glycoproteins Homologous to Human and Rat Cystatin
  186. Binding of androgen-receptor complexes to α2u-globulin genes and to the long terminal repeat of mouse mammary tumor virus
  187. Kallikrein-related protease in the rat ventral prostate: cDNA cloning and androgen regulation
  188. Glucocorticoid receptor binding to defined regions of α2 u-globulin genes
  189. Comparison of the 5' upstream putative regulatory sequences of three members of the alpha2u-globulin gene family
  190. New Selection Marker for Plant Transformation