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  1. Multiplex staining depicts the immune infiltrate in colitis-induced colon cancer model

    Article • Scientific Reports, September 2019, Springer Science + Business Media

    PhD Paola Spessotto

  2. Abrogation of EMILIN1-β1 integrin interaction promotes experimental colitis and colon carcinogenesis

    Article • Matrix Biology, August 2019, Elsevier

    PhD Paola Spessotto

  3. The Probe Based Confocal Laser Endomicroscopy (pCLE) in Locally Advanced Gastric Cancer: A Powerful Technique for Real–Time Analysis of Vasculature

    Article • Frontiers in Oncology, June 2019, Frontiers

    PhD Paola Spessotto

  4. Endomicroscopy for HGNEC diagnosis

    Article • OncoTargets and Therapy, June 2019, Dove Medical Press

    Renato Cannizzaro, PhD Paola Spessotto, Giovanni Guarnieri

  5. Loss of Multimerin-2 and EMILIN-2 Expression in Gastric Cancer Associate with Altered Angiogenesis

    Article • International Journal of Molecular Sciences, December 2018, MDPI AG

    PhD Paola Spessotto

  6. Integrin binding site within the gC1q domain orchestrates EMILIN-1-induced lymphangiogenesis

    Article • Matrix Biology, October 2018, Elsevier

    PhD Paola Spessotto

  7. The α4β1/EMILIN1 interaction discloses a novel and unique integrin-ligand type of engagement

    Article • Matrix Biology, March 2018, Elsevier

    PhD Paola Spessotto

  8. The angiostatic molecule Multimerin 2 is processed by MMP-9 to allow sprouting angiogenesis

    Article • Matrix Biology, December 2017, Elsevier

    PhD Paola Spessotto

  9. Probe-based confocal laser endomicroscopy for in vivo evaluation of the tumor vasculature in gastric and rectal carcinomas

    Article • Scientific Reports, August 2017, Springer Science + Business Media

    PhD Paola Spessotto

  10. Common biological phenotypes characterize the acquisition of platinum-resistance in epithelial ovarian cancer cells

    Article • Scientific Reports, August 2017, Springer Science + Business Media

    PhD Paola Spessotto

  11. The extracellular matrix protein EMILIN1 silences the RAS-ERK pathway via α4β1 integrin and decreases tumor cell growth

    Article • Oncotarget, February 2017, Impact Journals, LLC

    PhD Paola Spessotto

  12. Neutrophil elastase cleavage of the gC1q domain impairs the EMILIN1-α4β1 integrin interaction, cell adhesion and anti-proliferative activity

    Article • Scientific Reports, January 2017, Springer Science + Business Media

    PhD Paola Spessotto

  13. Tumor microenvironment in diffuse large B-cell lymphoma: Matrixmetalloproteinases activation is mediated by osteopontin overexpression

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, March 2016, Elsevier

    Professor Claudio Guarneri, PhD Paola Spessotto

  14. Local inhibition of elastase reduces EMILIN1 cleavage reactivating lymphatic vessel function in a mouse lymphoedema model

    Article • Clinical Science, February 2016, Portland Press Ltd.

    PhD Paola Spessotto

  15. Diagnostic Exome Sequencing Identifies a Novel Gene, EMILIN1 , Associated with Autosomal‐Dominant Hereditary Connective Tissue Disease

    Article • Human Mutation, November 2015, Wiley

    Ms Kelly D Farwell Hagman, PhD Paola Spessotto

  16. Functional osteoclastogenesis: the baseline variability in blood donor precursors is not associated with age and gender

    Article • Oncotarget, September 2015, Impact Journals, LLC

    PhD Paola Spessotto

  17. Neutrophil elastase-dependent cleavage compromises the tumor suppressor role of EMILIN1

    Article • Matrix Biology, February 2014, Elsevier

    PhD Paola Spessotto

  18. EMILIN1/α9β1 Integrin Interaction Is Crucial in Lymphatic Valve Formation and Maintenance

    Article • Molecular and Cellular Biology, September 2013, ASM Journals

    PhD Paola Spessotto

  19. An EMILIN1-Negative Microenvironment Promotes Tumor Cell Proliferation and Lymph Node Invasion

    Article • Cancer Prevention Research, July 2012, American Association for Cancer Research (AACR)

    PhD Paola Spessotto

  20. EMILIN1–α4/α9 integrin interaction inhibits dermal fibroblast and keratinocyte proliferation

    Article • The Journal of Cell Biology, January 2012, Rockefeller University Press

    PhD Paola Spessotto

  21. Endomicroscopy and Cancer: A New Approach to the Visualization of Neoangiogenesis

    Article • Gastroenterology Research and Practice, January 2012, Hindawi Publishing Corporation

    PhD Paola Spessotto

  22. The EMILIN/Multimerin Family

    Article • Frontiers in Immunology, January 2012, Frontiers

    PhD Paola Spessotto

  23. MMP-13 stimulates osteoclast differentiation and activation in tumour breast bone metastases

    Article • October 2011, Springer Science + Business Media

    PhD Paola Spessotto, Claudio Tripodo

  24. EMILIN1–α4/α9 integrin interaction inhibits dermal fibroblast and keratinocyte proliferation

    Article • The Journal of Cell Biology, September 2011, Rockefeller University Press

    PhD Paola Spessotto

  25. Cancer Stem Cells and the Microenvironment

    Article • September 2011, Springer Science + Business Media

    PhD Paola Spessotto

  26. Blood-derived human osteoclast resorption activity is impaired by Hyaluronan-CD44 engagement via a p38-dependent mechanism

    Article • Journal of Cellular Physiology, December 2010, Wiley

    PhD Paola Spessotto

  27. An Alternative Role of C1q in Cell Migration and Tissue Remodeling: Contribution to Trophoblast Invasion and Placental Development

    Article • The Journal of Immunology, September 2010, The American Association of Immunologists

    PhD Paola Spessotto, Claudio Tripodo

  28. MFSD2A is a novel lung tumor suppressor gene modulating cell cycle and matrix attachment

    Article • Molecular Cancer, January 2010, Springer Science + Business Media

    PhD Paola Spessotto

  29. Role of E2F1-Cyclin E1-Cyclin E2 Circuit in Human Coronary Smooth Muscle Cell Proliferation and Therapeutic Potential of Its Downregulation by siRNAs

    Article • Molecular Medicine, June 2009, Springer Science + Business Media

    PhD Paola Spessotto

  30. A newly generated functional antibody identifies Tn antigen as a novel determinant in the cancer cell-lymphatic endothelium interaction

    Article • Glycobiology, June 2009, Oxford University Press (OUP)

    PhD Paola Spessotto

  31. The Solution Structure of EMILIN1 Globular C1q Domain Reveals a Disordered Insertion Necessary for Interaction with the α4β1 Integrin

    Article • Journal of Biological Chemistry, May 2008, American Society for Biochemistry & Molecular Biology (ASBMB)

    PhD Paola Spessotto

  32. Emilin1 Deficiency Causes Structural and Functional Defects of Lymphatic Vasculature

    Article • Molecular and Cellular Biology, April 2008, ASM Journals

    PhD Paola Spessotto

  33. Expression profiles in malignant fibrous histiocytomas: Clues for differentiating ‘spindle cell’ and ‘pleomorphic’ subtypes

    Article • European Journal of Cancer, January 2008, Elsevier

    PhD Paola Spessotto

  34. Laminin-332 (Laminin-5) is the major motility ligand for B cell chronic lymphocytic leukemia

    Article • Matrix Biology, July 2007, Elsevier

    PhD Paola Spessotto

  35. EMILIN1 represents a major stromal element determining human trophoblast invasion of the uterine wall

    Article • Journal of Cell Science, November 2006, The Company of Biologists

    PhD Paola Spessotto

  36. Inhibition of B16 Melanoma Metastases with the Ruthenium Complex Imidazolium trans-Imidazoledimethylsulfoxide-tetrachlororuthenate and Down-Regulation of Tumor Cell Invasion

    Article • Journal of Pharmacology and Experimental Therapeutics, December 2005, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    PhD Paola Spessotto

  37. p27Kip1-stathmin interaction influences sarcoma cell migration and invasion

    Article • Cancer Cell, January 2005, Elsevier

    PhD Paola Spessotto

  38. VE-cadherin is a critical molecule for trophoblast?endothelial cell interaction in decidual spiral arteries

    Article • Experimental Cell Research, October 2004, Elsevier

    PhD Paola Spessotto

  39. Actin-dependent tumour cell adhesion after short-term exposure to the antimetastasis ruthenium complex NAMI-A

    Article • European Journal of Cancer, June 2004, Elsevier

    PhD Paola Spessotto

  40. Role of α8 integrin in mesangial cell adhesion, migration, and proliferation

    Article • Kidney International, July 2003, Elsevier

    PhD Paola Spessotto

  41. Preferential locomotion of leukemic cells towards laminin isoforms 8 and 10

    Article • Matrix Biology, June 2003, Elsevier

    PhD Paola Spessotto

  42. Vascular PG-M/versican variants promote platelet adhesion at low shear rates and cooperate with collagens to induce aggregation

    Article • The FASEB Journal, December 2002, Federation of American Societies For Experimental Biology (FASEB)

    PhD Paola Spessotto

  43. β1Integrin-dependent Cell Adhesion to EMILIN-1 Is Mediated by the gC1q Domain

    Article • Journal of Biological Chemistry, November 2002, American Society for Biochemistry & Molecular Biology (ASBMB)

    PhD Paola Spessotto

  44. H2O2 induces translocation of APE/Ref-1 to mitochondria in the Raji B-cell line

    Article • Journal of Cellular Physiology, October 2002, Wiley

    PhD Paola Spessotto

  45. Hyaluronan–CD44 interaction hampers migration of osteoclast-like cells by down-regulating MMP-9

    Article • The Journal of Cell Biology, September 2002, Rockefeller University Press

    PhD Paola Spessotto

  46. Distribution of PG-M/Versican Variants in Human Tissues andde NovoExpression of Isoform V3 upon Endothelial Cell Activation, Migration, and Neoangiogenesisin Vitro

    Article • Journal of Biological Chemistry, September 2002, American Society for Biochemistry & Molecular Biology (ASBMB)

    PhD Paola Spessotto

  47. Antigene Effect in K562 Cells of a PEG-Conjugated Triplex-Forming Oligonucleotide Targeted to thebcr/ablOncogene†

    Article • Biochemistry, January 2002, American Chemical Society (ACS)

    PhD Paola Spessotto

  48. Differential Expression of IRS-1 and IRS-2 in Uterine Leiomyosarcomas with Distinct Oncogenic Phenotypes: Lack of Correlation with Downstream Signaling Events

    Article • Sarcoma, January 2002, Hindawi Publishing Corporation

    PhD Paola Spessotto

  49. Improving Fluorescence-Based Assays for the In Vitro Analysis of Cell Adhesion and Migration

    Article • Molecular Biotechnology, January 2002, Springer Science + Business Media

    PhD Paola Spessotto

  50. The EMILIN protein family

    Article • Matrix Biology, August 2000, Elsevier

    PhD Paola Spessotto

  51. Article • Inflammation, January 2000, Springer Science + Business Media

    PhD Paola Spessotto

  52. Paracrine effects of IL- 4 transfection on TS/A adenocarcinoma cells mediate reducedin Vivo growth

    Article • Pathology & Oncology Research, June 1999, Springer Science + Business Media

    PhD Paola Spessotto

  53. Identification of Domains Responsible for von Willebrand Factor Type VI Collagen Interaction Mediating Platelet Adhesion under High Flow

    Article • Journal of Biological Chemistry, January 1999, American Society for Biochemistry & Molecular Biology (ASBMB)

    PhD Paola Spessotto

  54. Human eosinophil peroxidase enhances tumor necrosis factor and hydrogen peroxide release by human monocyte-derived macrophages

    Article • European Journal of Immunology, May 1995, Wiley

    PhD Paola Spessotto

  55. Identification of elastase in human eosinophils: Immunolocalization, isolation, and partial characterization

    Article • Archives of Biochemistry and Biophysics, January 1992, Elsevier

    PhD Paola Spessotto