All Stories

  1. Discovery of allosteric mechanism of beta-lactam binding in non-classical transpeptidases

    Article • eLife, April 2022, eLife

    Dr Pankaj Kumar

  2. Discovery of most conserved epitope regions in COVID-19 virus from across the globe.

    Article • June 2020, MDPI AG

    Dr Pankaj Kumar

  3. A nucleotide-dependent oligomerization of the Escherichia coli replication initiator DnaA requires residue His136 for remodeling of the chromosomal origin

    Article • Nucleic Acids Research, October 2019, Oxford University Press (OUP)

    Dr Pankaj Kumar

  4. Recent advances with Treg depleting fusion protein toxins for cancer immunotherapy

    Article • Immunotherapy, September 2019, Future Medicine

    Dr Pankaj Kumar

  5. Second-generation IL-2 receptor-targeted diphtheria fusion toxin exhibits antitumor activity and synergy with anti–PD-1 in melanoma

    Article • Proceedings of the National Academy of Sciences, February 2019, Proceedings of the National Academy of Sciences

    Dr Pankaj Kumar

  6. Repurposing of Carbapenems for the Treatment of Drug-Resistant Tuberculosis

    Article • January 2019, Springer Science + Business Media

    Dr Pankaj Kumar

  7. Mechanism based drug discovery against Mycobacterium abscessus by targeting L,D-transpeptidases

    Article • Antimicrobial Agents and Chemotherapy, July 2017, ASM Journals

    Dr Pankaj Kumar

  8. LdtMav2, a nonclassical transpeptidase and susceptibility of Mycobacterium avium to carbapenems

    Article • Future Microbiology, June 2017, Future Medicine

    Dr Pankaj Kumar

  9. Structural insight into the inactivation of Mycobacterium tuberculosis non-classical transpeptidase LdtMt2 by biapenem and tebipenem

    Article • BMC Biochemistry, May 2017, Springer Science + Business Media

    Dr Pankaj Kumar

  10. Carbapenem drug resistance mechanism in Mycobacterium tuberculosis

    Article • Antimicrobial Agents and Chemotherapy, January 2017, ASM Journals

    Dr Pankaj Kumar

  11. Inhibition of innate immune cytosolic surveillance by an M. tuberculosis phosphodiesterase

    Article • Nature Chemical Biology, December 2016, Nature

    Dr Pankaj Kumar

  12. Crystal structure of Mycobacterium tuberculosis L,D-transpeptidase 2 with carbapenem drug T224

    Article • November 2016, Protein Data Bank, Rutgers University

    Dr Pankaj Kumar

  13. Development of new antibiotics for treatment of drug resistant Tuberculosis

    Article • Nature Chemical Biology, November 2016, Nature

    Dr Sean Ekins, Dr Pankaj Kumar

  14. Crystal structure of Mycobacterium tuberculosis L,D-transpeptidase 2 with carbapenem drug T208

    Article • October 2016, Protein Data Bank, Rutgers University

    Dr Pankaj Kumar

  15. Crystal structure of Mycobacterium tuberculosis L,D-transpeptidase 2 with carbapenem drug T210

    Article • October 2016, Protein Data Bank, Rutgers University

    Dr Pankaj Kumar

  16. Crystal structure of Mycobacterium tuberculosis L,D-transpeptidase 2 with carbapenem drug T206 in conformation A

    Article • October 2016, Protein Data Bank, Rutgers University

    Dr Pankaj Kumar

  17. Role of a non-canonical surface of Rad6 in ubiquitin conjugating activity

    Article • Nucleic Acids Research, August 2015, Oxford University Press (OUP)

    Dr Pankaj Kumar

  18. Structure of the yeast Bre1 RING domain

    Article • Proteins Structure Function and Bioinformatics, April 2015, Wiley

    Dr Pankaj Kumar

  19. The crystal structure reveals the molecular mechanism of bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II (Rv1415) fromMycobacterium tuberculosis

    Article • Acta Crystallographica Section D Biological Crystallography, August 2013, International Union of Crystallography

    Dr Pankaj Kumar

  20. Corrigendum to “Structural basis for pH dependent monomer–dimer transition of 3,4-dihydroxy 2-butanone-4-phosphate synthase domain from Mycobacterium tuberculosis” [J. Struct. Biol. 174 (2011) 374–384]

    Article • Journal of Structural Biology, March 2013, Elsevier

    Dr Pankaj Kumar

  21. Structural basis for pH dependent monomer–dimer transition of 3,4-dihydroxy 2-butanone-4-phosphate synthase domain from Mycobacterium tuberculosis

    Article • Journal of Structural Biology, May 2011, Elsevier

    Dr Pankaj Kumar

  22. Crystal structure analysis of icosahedral lumazine synthase fromSalmonella typhimurium, an antibacterial drug target

    Article • Acta Crystallographica Section D Biological Crystallography, January 2011, International Union of Crystallography

    Dr Pankaj Kumar

  23. Potential anti-bacterial drug target: Structural characterization of 3,4-dihydroxy-2-butanone-4-phosphate synthase from Salmonella typhimurium LT2

    Article • Proteins Structure Function and Bioinformatics, November 2010, Wiley

    Dr Pankaj Kumar