All Stories

  1. Chronic lymphocytic leukemia patient-derived xenografts recapitulate clonal evolution to Richter transformation

    Article • Leukemia, November 2023, Springer Science + Business Media

    PhD Pablo M. Garcia-Roves

  2. The antioxidant l-Ergothioneine prevents cystine lithiasis in the Slc7a9 mouse model of cystinuria

    Article • Redox Biology, August 2023, Elsevier

    PhD Pablo M. Garcia-Roves

  3. Energy substrate metabolism, mitochondrial structure and oxidative stress after cardiac ischemia-reperfusion in mice lacking UCP3

    Article • Free Radical Biology and Medicine, August 2023, Elsevier

    PhD Pablo M. Garcia-Roves

  4. Editorial: Untangling energy metabolism in skeletal muscle: From physiology to pharmacology

    Article • Frontiers in Physiology, December 2022, Frontiers

    PhD Pablo M. Garcia-Roves

  5. Orally administered Odoribacter laneus improves glucose control and inflammatory profile in obese mice by depleting circulating succinate

    Article • Microbiome, August 2022, Springer Science + Business Media

    PhD Pablo M. Garcia-Roves

  6. Glycosylation defects, offset by PEPCK-M, drive entosis in breast carcinoma cells

    Article • Cell Death and Disease, August 2022, Springer Science + Business Media

    PhD Pablo M. Garcia-Roves

  7. Detection of early seeding of Richter transformation in chronic lymphocytic leukemia

    Article • Nature Reports Stem Cells, August 2022, Springer Science + Business Media

    PhD Pablo M. Garcia-Roves

  8. Remission of obesity and insulin resistance is not sufficient to restore mitochondrial homeostasis in visceral adipose tissue

    Article • Redox Biology, August 2022, Elsevier

    PhD Pablo M. Garcia-Roves, Joel Montane

  9. Angiocrine polyamine production regulates adiposity

    Article • Nature Metabolism, March 2022, Springer Science + Business Media

    PhD Pablo M. Garcia-Roves

  10. Mitochondrial cristae-remodeling protein OPA1 in POMC neurons couples Ca2+ homeostasis with adipose tissue lipolysis

    Article • Cell Metabolism, August 2021, Elsevier

    PhD Pablo M. Garcia-Roves

  11. Activation of the Integrated Stress Response and ER Stress Protect from Fluorizoline-Induced Apoptosis in HEK293T and U2OS Cell Lines

    Article • International Journal of Molecular Sciences, June 2021, MDPI AG

    PhD Pablo M. Garcia-Roves

  12. Effects of Lifestyle Intervention in Tissue-Specific Lipidomic Profile of Formerly Obese Mice

    Article • International Journal of Molecular Sciences, April 2021, MDPI AG

    PhD Pablo M. Garcia-Roves

  13. NRF2 function in osteocytes is required for bone homeostasis and drives osteocytic gene expression

    Article • Redox Biology, April 2021, Elsevier

    PhD Pablo M. Garcia-Roves

  14. PEPCK-M recoups tumor cell anabolic potential in a PKC-ζ-dependent manner

    Article • Cancer & Metabolism, January 2021, Springer Science + Business Media

    PhD Pablo M. Garcia-Roves

  15. Obesity causes irreversible mitochondria failure in visceral adipose tissue despite successful anti-obesogenic lifestyle-based interventions

    Article • July 2020, Cold Spring Harbor Laboratory Press

    PhD Pablo M. Garcia-Roves

  16. Pharmacology and preclinical validation of a novel anticancer compound targeting PEPCK-M

    Article • Biomedicine & Pharmacotherapy, January 2020, Elsevier

    PhD Pablo M. Garcia-Roves

  17. Phosphoenolpyruvate from Glycolysis and PEPCK Regulate Cancer Cell Fate by Altering Cytosolic Ca2+

    Article • Cells, December 2019, MDPI AG

    PhD Pablo M. Garcia-Roves

  18. Dietary Calanus oil recovers metabolic flexibility and rescues postischemic cardiac function in obese female mice

    Article • AJP Heart and Circulatory Physiology, August 2019, American Physiological Society

    PhD Pablo M. Garcia-Roves

  19. Glucose Restriction Promotes Osteocyte Specification by Activating a PGC-1α-Dependent Transcriptional Program

    Article • iScience, May 2019, Elsevier

    PhD Pablo M. Garcia-Roves

  20. Calorie restriction prevents diet-induced insulin resistance independently of PGC-1-driven mitochondrial biogenesis in white adipose tissue

    Article • The FASEB Journal, February 2019, Federation of American Societies For Experimental Biology (FASEB)

    Dr Josep A Villena, PhD Pablo M. Garcia-Roves, Luis Cervela

  21. Adipose tissue mitochondrial dysfunction in human obesity is linked to a specific DNA methylation signature in adipose-derived stem cells

    Article • International Journal of Obesity, September 2018, Springer Science + Business Media

    PhD Pablo M. Garcia-Roves

  22. Correction to: the disruption of mitochondrial axonal transport is an early event in neuroinflammation

    Article • Journal of Neuroinflammation, October 2017, Springer Science + Business Media

    PhD Pablo M. Garcia-Roves

  23. MacroH2A1.1 regulates mitochondrial respiration by limiting nuclear NAD+ consumption

    Article • Nature Structural & Molecular Biology, October 2017, Nature

    PhD Pablo M. Garcia-Roves

  24. Emerging Concepts in Diabetes: Mitochondrial Dynamics and Glucose Homeostasis

    Article • Current Diabetes Reviews, July 2017, Bentham Science Publishers

    PhD Pablo M. Garcia-Roves

  25. Editorial:Dissecting the Role of Mitochondria in the Pathophysiology of Type-2 Diabetes and Obesity: Novel Concepts and Challenges

    Article • Current Diabetes Reviews, July 2017, Bentham Science Publishers

    PhD Pablo M. Garcia-Roves

  26. Mitochondrial Dynamics Mediated by Mitofusin 1 Is Required for POMC Neuron Glucose-Sensing and Insulin Release Control

    Article • Cell Metabolism, June 2017, Elsevier

    PhD Pablo M. Garcia-Roves, Andrés Vidal-Itriago

  27. Mitochondrial GSH replenishment as a potential therapeutic approach for Niemann Pick type C disease

    Article • Redox Biology, April 2017, Elsevier

    PhD Pablo M. Garcia-Roves

  28. Dietary Betaine Supplementation Increases Fgf21 Levels to Improve Glucose Homeostasis and Reduce Hepatic Lipid Accumulation in Mice

    Article • Diabetes, February 2016, American Diabetes Association

    PhD Pablo M. Garcia-Roves

  29. Adipose tissue glycogen accumulation is associated with obesity-linked inflammation in humans

    Article • Molecular Metabolism, January 2016, Elsevier

    PhD Pablo M. Garcia-Roves

  30. The disruption of mitochondrial axonal transport is an early event in neuroinflammation

    Article • Journal of Neuroinflammation, August 2015, Springer Science + Business Media

    PhD Pablo M. Garcia-Roves

  31. Reduced α-MSH Underlies Hypothalamic ER-Stress-Induced Hepatic Gluconeogenesis

    Article • Cell Reports, July 2015, Elsevier

    PhD Pablo M. Garcia-Roves

  32. High-Resolution Respirometry for Mitochondrial Characterization of Ex Vivo Mouse Tissues

    Article • June 2015, Wiley

    PhD Pablo M. Garcia-Roves

  33. Circulating miR-192 and miR-193b Are Markers of Prediabetes and Are Modulated by an Exercise Intervention

    Article • The Journal of Clinical Endocrinology & Metabolism, March 2015, Endocrine Society

    PhD Pablo M. Garcia-Roves, Joan Aureli Cadefau

  34. SIRT1 enhances glucose tolerance by potentiating brown adipose tissue function

    Article • Molecular Metabolism, February 2015, Elsevier

    PhD Pablo M. Garcia-Roves

  35. Diabetes Mellitus and Metabolic Syndrome

    Article • January 2015, Springer Science + Business Media

    PhD Pablo M. Garcia-Roves

  36. ASMase regulates autophagy and lysosomal membrane permeabilization and its inhibition prevents early stage non-alcoholic steatohepatitis

    Article • Journal of Hepatology, November 2014, Elsevier

    PhD Pablo M. Garcia-Roves

  37. Nutrient Intake and Food Habits of Soccer Players: Analyzing the Correlates of Eating Practice

    Article • Nutrients, July 2014, MDPI AG

    PhD Pablo M. Garcia-Roves

  38. Protein Tyrosine Phosphatase-1B Modulates Pancreatic β-cell Mass

    Article • PLoS ONE, February 2014, PLOS

    PhD Pablo M. Garcia-Roves

  39. Effects of AMPK Activation on Insulin Sensitivity and Metabolism in Leptin-Deficientob/obMice

    Article • Diabetes, January 2014, American Diabetes Association

    PhD Pablo M. Garcia-Roves

  40. Mitochondrial dysfunction in non-alcoholic fatty liver disease and insulin resistance: Cause or consequence?

    Article • Free Radical Research, October 2013, Taylor & Francis

    PhD Pablo M. Garcia-Roves

  41. Effect of leptin treatment on mitochondrial function in obese leptin-deficient ob/ob mice

    Article • Metabolism, September 2013, Elsevier

    PhD Pablo M. Garcia-Roves

  42. Mitofusin 2 in POMC Neurons Connects ER Stress with Leptin Resistance and Energy Imbalance

    Article • Cell, September 2013, Elsevier

    PhD Pablo M. Garcia-Roves

  43. Expression of carnitine palmitoyl-CoA transferase-1B is influenced by a cis-acting eQTL in two chicken lines selected for high and low body weight

    Article • Physiological Genomics, May 2013, American Physiological Society

    PhD Pablo M. Garcia-Roves

  44. Is there a relationship between the playing position of soccer players and their food and macronutrient intake?

    Article • Applied Physiology Nutrition and Metabolism, April 2012, Canadian Science Publishing

    PhD Pablo M. Garcia-Roves

  45. Tissue-specific control of mitochondrial respiration in obesity-related insulin resistance and diabetes

    Article • AJP Endocrinology and Metabolism, March 2012, American Physiological Society

    PhD Pablo M. Garcia-Roves

  46. Hypothalamic mitochondrial dysfunction associated with anorexia in the anx/anx mouse

    Article • Proceedings of the National Academy of Sciences, October 2011, Proceedings of the National Academy of Sciences

    PhD Pablo M. Garcia-Roves

  47. Increased Hepatic Insulin Sensitivity in Mice Lacking Inhibitory Leptin Receptor Signals

    Article • Endocrinology, June 2011, Endocrine Society

    PhD Pablo M. Garcia-Roves

  48. Laforin, a dual specificity phosphatase involved in Lafora disease, regulates insulin response and whole-body energy balance in mice

    Article • Human Molecular Genetics, April 2011, Oxford University Press (OUP)

    PhD Pablo M. Garcia-Roves

  49. Exercise intensity-dependent regulation of peroxisome proliferator-activated receptor γ coactivator-1α mRNA abundance is associated with differential activation of upstream signalling kinases in human skeletal muscle

    Article • The Journal of Physiology, May 2010, Wiley

    PhD Pablo M. Garcia-Roves

  50. Adenosine A3 receptors regulate heart rate, motor activity and body temperature

    Article • Acta Physiologica, April 2010, Wiley

    PhD Pablo M. Garcia-Roves

  51. Constitutively active calcineurin in skeletal muscle increases endurance performance and mitochondrial respiratory capacity

    Article • AJP Endocrinology and Metabolism, January 2010, American Physiological Society

    PhD Pablo M. Garcia-Roves

  52. Spatial insulin signalling in isolated skeletal muscle preparations

    Article • Journal of Cellular Biochemistry, January 2010, Wiley

    PhD Pablo M. Garcia-Roves

  53. Effects of fibre type and diffusion distance on mouse skeletal muscle glycogen content in vitro

    Article • Journal of Cellular Biochemistry, August 2009, Wiley

    PhD Pablo M. Garcia-Roves

  54. Relationship between AMPK and the transcriptional balance of clock-related genes in skeletal muscle

    Article • AJP Endocrinology and Metabolism, November 2008, American Physiological Society

    PhD Pablo M. Garcia-Roves

  55. Gain-of-function R225Q Mutation in AMP-activated Protein Kinase γ3 Subunit Increases Mitochondrial Biogenesis in Glycolytic Skeletal Muscle

    Article • Journal of Biological Chemistry, October 2008, American Society for Biochemistry & Molecular Biology (ASBMB)

    PhD Pablo M. Garcia-Roves

  56. Food preferences do not influence adolescent high-level athletes’ dietary intake

    Article • Appetite, March 2008, Elsevier

    PhD Pablo M. Garcia-Roves

  57. Malonyl CoenzymeA Decarboxylase Regulates Lipid and Glucose Metabolism in Human Skeletal Muscle

    Article • Diabetes, February 2008, American Diabetes Association

    PhD Pablo M. Garcia-Roves

  58. Raising plasma fatty acid concentration induces increased biogenesis of mitochondria in skeletal muscle

    Article • Proceedings of the National Academy of Sciences, June 2007, Proceedings of the National Academy of Sciences

    PhD Pablo M. Garcia-Roves

  59. Role of AMP Kinase and PPARδ in the Regulation of Lipid and Glucose Metabolism in Human Skeletal Muscle

    Article • Journal of Biological Chemistry, May 2007, American Society for Biochemistry & Molecular Biology (ASBMB)

    PhD Pablo M. Garcia-Roves

  60. Activated Ampkgamma3 Promotes Skeletal Muscle Mitochondrial Biogenesis, Independent Of Fiber Type Transformation

    Article • Medicine & Science in Sports & Exercise, May 2007, Wolters Kluwer Health

    PhD Pablo M. Garcia-Roves

  61. Calcineurin Regulates Skeletal Muscle Metabolism via Coordinated Changes in Gene Expression

    Article • Journal of Biological Chemistry, November 2006, American Society for Biochemistry & Molecular Biology (ASBMB)

    PhD Pablo M. Garcia-Roves

  62. Exercise-induced Mitochondrial Biogenesis Begins before the Increase in Muscle PGC-1α Expression

    Article • Journal of Biological Chemistry, November 2006, American Society for Biochemistry & Molecular Biology (ASBMB)

    PhD Pablo M. Garcia-Roves

  63. Investigation of the role of AMPK in Mitochondrial Biogenesis of Skeletal Muscle

    Article • Medicine & Science in Sports & Exercise, November 2006, Wolters Kluwer Health

    PhD Pablo M. Garcia-Roves

  64. Role of calcineurin in exercise-induced mitochondrial biogenesis

    Article • AJP Endocrinology and Metabolism, June 2006, American Physiological Society

    PhD Pablo M. Garcia-Roves

  65. Opposite Transcriptional Regulation in Skeletal Muscle of AMP-activated Protein Kinase γ3 R225Q TransgenicVersusKnock-out Mice

    Article • Journal of Biological Chemistry, January 2006, American Society for Biochemistry & Molecular Biology (ASBMB)

    PhD Pablo M. Garcia-Roves

  66. Calcineurin Does Not Mediate Exercise-Induced Increase in Muscle GLUT4

    Article • Diabetes, February 2005, American Diabetes Association

    PhD Pablo M. Garcia-Roves

  67. Food Habits and Nutritional Status Assessment of Adolescent Soccer Players. A Necessary and Accurate Approach

    Article • Canadian Journal of Applied Physiology, February 2005, Canadian Science Publishing

    PhD Pablo M. Garcia-Roves

  68. Calpain System Regulates Muscle Mass and Glucose Transporter GLUT4 Turnover

    Article • Journal of Biological Chemistry, March 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    PhD Pablo M. Garcia-Roves

  69. Prevention of glycogen supercompensation prolongs the increase in muscle GLUT4 after exercise

    Article • AJP Endocrinology and Metabolism, October 2003, American Physiological Society

    PhD Pablo M. Garcia-Roves

  70. Effect of Carbohydrate Feeding During Recovery from Prolonged Running on Muscle Glycogen Metabolism During Subsequent Exercise

    Article • International Journal of Sports Medicine, August 2003, Thieme Publishing Group

    PhD Pablo M. Garcia-Roves

  71. Post-exercise vitamin C supplementation and recovery from demanding exercise

    Article • European Journal of Applied Physiology and Occupational Physiology, May 2003, Springer Science + Business Media

    PhD Pablo M. Garcia-Roves

  72. Eating Pattern and Nutritional Status of International Elite Flatwater Paddlers

    Article • International Journal of Sport Nutrition and Exercise Metabolism, June 2000, Human Kinetics

    PhD Pablo M. Garcia-Roves

  73. Comparison of Dietary Intake and Eating Behavior of Professional Road Cyclists during Training and Competition

    Article • International Journal of Sport Nutrition and Exercise Metabolism, March 2000, Human Kinetics

    PhD Pablo M. Garcia-Roves

  74. CARBOHYDRATE AVAILABILITY DETERMINES ENDURANCE RUNNING CAPACITY IN FASTED SUBJECTS

    Article • Medicine & Science in Sports & Exercise, May 1999, Wolters Kluwer Health

    PhD Pablo M. Garcia-Roves

  75. Macronutrients Intake of Top Level Cyclists During Continuous Competition - Change in the Feeding Pattern

    Article • International Journal of Sports Medicine, January 1998, Thieme Publishing Group

    PhD Pablo M. Garcia-Roves