All Stories

  1. Profiling Glycoproteins Enriched by Multinanoparticle Protein Corona
  2. The protease Cathepsin K can debulk the cancer glycocalyx
  3. Extracting Informative Glycan-Specific Ions From Glycopeptide MS/MS Spectra With GlyCounter
  4. Sialoglycans on human T cells attenuate death programs executed through the Fas pathway
  5. Antibodies disrupt bacterial adhesion by ligand mimicry and allosteric interference
  6. Profiling glycoproteins enriched by multi-nanoparticle protein corona
  7. Understanding m/z range settings for MS/MS scans: a case study with intact glycopeptides
  8. Profiling glycoproteins enriched by surface-functionalized nanoparticles
  9. Sialoglycans on human T cells attenuate death programs executed through the Fas pathway
  10. Accelerating the stride toward functional glycoproteomics
  11. Improvements in Glycoproteomics through Architecture Changes to the Orbitrap Tribrid MS Platform
  12. Publisher Correction: irCLIP-RNP and Re-CLIP reveal patterns of dynamic protein assemblies on RNA
  13. Understanding m/z range settings for MS/MS scans: a case study with intact glycopeptides
  14. irCLIP-RNP and Re-CLIP reveal patterns of dynamic protein assemblies on RNA
  15. Extracting informative glycan-specific ions from glycopeptide MS/MS spectra with GlyCounter
  16. Comparative analysis of glycoproteomic software using a tailored glycan database
  17. Revisiting the Effect of Trypsin Digestion Buffers on Artificial Deamidation
  18. Antibodies disrupt bacterial adhesion by ligand mimicry and allosteric interference
  19. Autonomous Dissociation-type Selection for Glycoproteomics Using a Real-Time Library Search
  20. Sialylated glycoproteins suppress immune cell killing by binding to Siglec-7 and Siglec-9 in prostate cancer
  21. “Comparative Analysis of Glycoproteomic Software Using a Tailored Glycan Database”
  22. Instrumentation at the Leading Edge of Proteomics
  23. Instrumentation at the leading edge of proteomics
  24. Instrumentation at the leading edge of proteomics
  25. Microglia Mediate Contact-Independent Neuronal Network Remodeling via Secreted Neuraminidase-3 Associated with Extracellular Vesicles
  26. Elucidating the cellular determinants of targeted membrane protein degradation by lysosome-targeting chimeras
  27. Galectin-3 does not interact with RNA directly
  28. Microglia mediate contact-independent neuronal pruning via secreted Neuraminidase-3 associated with extracellular vesicles
  29. Design of a mucin-selective protease for targeted degradation of cancer-associated mucins
  30. Organism-wide, cell-type-specific secretome mapping of exercise training in mice
  31. The microenvironment dictates glycocalyx construction and immune surveillance
  32. Mutational screens highlight glycosylation as a modulator of colony-stimulating factor 3 receptor (CSF3R) activity
  33. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  34. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  35. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  36. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  37. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  38. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  39. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  40. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  41. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  42. Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  43. Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  44. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  45. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  46. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  47. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  48. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  49. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  50. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  51. MYC-driven synthesis of Siglec ligands is a glycoimmune checkpoint
  52. The 2022 Nobel Prize in Chemistry—sweet!
  53. Measuring the multifaceted roles of mucin-domain glycoproteins in cancer
  54. Organism-wide secretome mapping uncovers pathways of tissue crosstalk in exercise
  55. Deciphering O-glycoprotease substrate preferences with O-Pair Search
  56. Antibody-lectin chimeras for glyco-immune checkpoint blockade
  57. The human disease gene LYSET is essential for lysosomal enzyme transport and viral infection
  58. Lysosomal cathepsin D mediates endogenous mucin glycodomain catabolism in mammals
  59. Deciphering O-glycoprotease substrate preferences with O-Pair Search
  60. Glycoproteomics
  61. Revealing the human mucinome
  62. Targeting hypersialylation in multiple myeloma represents a novel approach to enhance NK cell–mediated tumor responses
  63. Design of a mucin-selective protease for targeted degradation of cancer-associated mucins
  64. Structure-guided mutagenesis of a mucin-selective metalloprotease from Akkermansia muciniphila alters substrate preferences
  65. Deciphering O-glycoprotease substrate preferences with O-Pair Search
  66. Practical Effects of Intramolecular Hydrogen Rearrangement in Electron Transfer Dissociation-Based Proteomics
  67. Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  68. Protocol for cell type-specific labeling, enrichment, and proteomic profiling of plasma proteins in mice
  69. The CD22-IGF2R interaction is a therapeutic target for microglial lysosome dysfunction in Niemann-Pick type C
  70. LYTACs that engage the asialoglycoprotein receptor for targeted protein degradation
  71. Synthetic Siglec-9 Agonists Inhibit Neutrophil Activation Associated with COVID-19
  72. Revealing the human mucinome
  73. Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
  74. Modulation of immune cell reactivity with cis -binding Siglec agonists
  75. A Pragmatic Guide to Enrichment Strategies for Mass Spectrometry–Based Glycoproteomics
  76. Synthetic Siglec-9 Agonists Inhibit Neutrophil Activation Associated with COVID-19
  77. Cell type-selective secretome profiling in vivo
  78. Electron-Based Dissociation Is Needed for O-Glycopeptides Derived from OpeRATOR Proteolysis
  79. O-Pair Search with MetaMorpheus for O-glycopeptide characterization
  80. Cell type-selective secretome profiling in vivo
  81. Optical Fiber-Enabled Photoactivation of Peptides and Proteins
  82. Lysosome Targeting Chimeras (LYTACs) That Engage a Liver-Specific Asialoglycoprotein Receptor for Targeted Protein Degradation
  83. Lysosome-targeting chimaeras for degradation of extracellular proteins
  84. Electron-Based Dissociation Is Needed for O-Glycopeptides Derived from OpeRATOR Proteolysis
  85. Top-Down Characterization of an Intact Monoclonal Antibody Using Activated Ion Electron Transfer Dissociation
  86. Optimal Dissociation Methods Differ for N- and O-Glycopeptides
  87. Optimal Dissociation Methods Differ for N- and O-glycopeptides
  88. O-Pair Search with MetaMorpheus for O-glycopeptide Characterization
  89. Optimal Dissociation Methods Differ for N- and O-glycopeptides
  90. Broad and thematic remodeling of the surfaceome and glycoproteome on isogenic cells transformed with driving proliferative oncogenes
  91. Lysosome Targeting Chimeras (LYTACs) for the Degradation of Secreted and Membrane Proteins
  92. Broad and thematic remodeling of the surface glycoproteome on isogenic cells transformed with driving proliferative oncogenes
  93. Mutating stress-defense regulators in yeast improves biofuels engineering
  94. Interactive Peptide Spectral Annotator: A Versatile Web-Based Tool for Proteomic Applications
  95. Lysosome Targeting Chimeras (LYTACs) for the Degradation of Secreted and Membrane Proteins
  96. Lysosome Targeting Chimeras (LYTACs) for the Degradation of Secreted and Membrane Proteins
  97. Capturing site-specific heterogeneity with large-scale N-glycoproteome analysis
  98. Rewired cellular signaling coordinates sugar and hypoxic responses for anaerobic xylose fermentation in yeast
  99. Top-Down Characterization of Proteins with Intact Disulfide Bonds Using Activated-Ion Electron Transfer Dissociation
  100. The Value of Activated Ion Electron Transfer Dissociation for High-Throughput Top-Down Characterization of Intact Proteins
  101. Improved Precursor Characterization for Data-Dependent Mass Spectrometry
  102. The Role of Electron Transfer Dissociation in Modern Proteomics
  103. Sequencing Larger Intact Proteins (30-70 kDa) with Activated Ion Electron Transfer Dissociation
  104. Activated Ion-Electron Transfer Dissociation Enables Comprehensive Top-Down Protein Fragmentation
  105. Negative Electron Transfer Dissociation Sequencing of Increasingly Sulfated Glycosaminoglycan Oligosaccharides on an Orbitrap Mass Spectrometer
  106. Implementation of Activated Ion Electron Transfer Dissociation on a Quadrupole-Orbitrap-Linear Ion Trap Hybrid Mass Spectrometer
  107. Phosphoproteomics with Activated Ion Electron Transfer Dissociation
  108. Sulfur Pentafluoride is a Preferred Reagent Cation for Negative Electron Transfer Dissociation
  109. Multi-omics Evidence for Inheritance of Energy Pathways in Red Blood Cells
  110. Full-Featured Search Algorithm for Negative Electron-Transfer Dissociation
  111. Genome Sequence and Analysis of a Stress-Tolerant, Wild-Derived Strain of Saccharomyces cerevisiae Used in Biofuels Research
  112. Proteomics Moves into the Fast Lane
  113. Mitochondrial protein hyperacetylation in the failing heart
  114. Enhanced Dissociation of Intact Proteins with High Capacity Electron Transfer Dissociation
  115. Phosphoproteomics in the Age of Rapid and Deep Proteome Profiling
  116. The Negative Mode Proteome with Activated Ion Negative Electron Transfer Dissociation (AI-NETD)
  117. A Calibration Routine for Efficient ETD in Large-Scale Proteomics
  118. Activated Ion Electron Transfer Dissociation for Improved Fragmentation of Intact Proteins
  119. Coupling Capillary Zone Electrophoresis with Electron Transfer Dissociation and Activated Ion Electron Transfer Dissociation for Top-Down Proteomics
  120. Neutron-Encoded Mass Signatures for Quantitative Top-Down Proteomics