All Stories

  1. Ensuring the collection of high-quality dried blood spot samples across multisite clinical studies

    Article • Bioanalysis, January 2017, Future Science

    Dr Neil Spooner

  2. From patient to tube: the importance of physiologically relevant quantitative bioanalytical assays

    Article • Bioanalysis, December 2016, Future Science

    Dr Neil Spooner

  3. Issues facing the bioanalytical community: summary of round table discussions

    Article • Bioanalysis, November 2016, Future Science

    Dr Neil Spooner, Stephanie S Cape

  4. The current skills gaps in analytical sciences are failing industry: debate at the 21st International Reid Bioanalytical Forum

    Article • Bioanalysis, July 2016, Future Science

    Dr Neil Spooner

  5. An investigation of the comparability of commercially sourced plasma and pharmaceutical study plasma, using total protein concentration

    Article • Bioanalysis, February 2016, Future Science

    Dr Neil Spooner, Mr Robert A Calloway

  6. Optimization of an automated IS addition system for use in high-throughput quantitative DBS analysis

    Article • Bioanalysis, November 2015, Future Science

    Dr Neil Spooner

  7. DBS and beyond

    Article • Bioanalysis, September 2015, Future Science

    Dr Neil Spooner, Christophe Stove

  8. DBS direct elution: optimizing performance in high-throughput quantitative LC–MS/MS analysis

    Article • Bioanalysis, September 2015, Future Science

    Dr Neil Spooner

  9. Investigation of Different Approaches to Incorporating Internal Standard in DBS Quantitative Bioanalytical Workflows and Their Effect on Nullifying Hematocrit-Based Assay Bias

    Article • Analytical Chemistry, May 2015, American Chemical Society (ACS)

    Dr Neil Spooner

  10. Attractive Design: An Elution Solvent Optimization Platform for Magnetic-Bead-based Fractionation Using Digital Microfluidics and Design of Experiments

    Article • Analytical Chemistry, April 2015, American Chemical Society (ACS)

    Dr Neil Spooner

  11. Quantitative bioanalysis of paracetamol in rats using volumetric absorptive microsampling (VAMS)

    Article • Journal of Pharmaceutical and Biomedical Analysis, April 2015, Elsevier

    Dr Neil Spooner

  12. A device for dried blood microsampling in quantitative bioanalysis: overcoming the issues associated blood hematocrit

    Article • Bioanalysis, April 2015, Future Science

    Dr Neil Spooner

  13. Direct Ionization of Solid-Phase Microextraction Fibers for Quantitative Drug Bioanalysis: From Peripheral Circulation to Mass Spectrometry Detection

    Article • Analytical Chemistry, January 2015, American Chemical Society (ACS)

    Dr Neil Spooner

  14. Reducing pre-clinical blood volumes for toxicokinetics: toxicologists, pathologists and bioanalysts unite

    Article • Bioanalysis, November 2014, Future Science

    Dr Neil Spooner

  15. EBF: reflection on bioanalytical assay requirements used to support liquid microsampling

    Article • Bioanalysis, October 2014, Future Science

    Dr Neil Spooner, Mr Philip Timmerman

  16. Volumetric Absorptive Microsampling: A Dried Sample Collection Technique for Quantitative Bioanalysis

    Article • Analytical Chemistry, August 2014, American Chemical Society (ACS)

    Dr Neil Spooner

  17. European Bioanalysis Forum continued plans to support liquid microsampling

    Article • Bioanalysis, July 2014, Future Science

    Dr Neil Spooner, Mr Philip Timmerman

  18. Pharmaceutical Perspectives of Use of Dried Blood Spots

    Article • June 2014, Wiley

    Dr Neil Spooner

  19. Integrating internal and external bioanalytical support to deliver a diversified pharmaceutical portfolio

    Article • Bioanalysis, May 2014, Future Science

    Dr Neil Spooner

  20. Overcoming the barriers to the uptake of nonclinical microsampling in regulatory safety studies

    Article • Drug Discovery Today, May 2014, Elsevier

    Dr Neil Spooner

  21. Multiplexed extraction and quantitative analysis of pharmaceuticals from DBS samples using digital microfluidics

    Article • Bioanalysis, February 2014, Future Science

    Dr Neil Spooner

  22. Preliminary investigation into the use of a real-time PCR method for the quantification of an oligonucleotide in human plasma and the development of novel acceptance criteria

    Article • Bioanalysis, January 2014, Future Science

    Dr Neil Spooner

  23. Assessment of the within- and between-lot variability of Whatman™ FTA® DMPK and 903® DBS papers and their suitability for the quantitative bioanalysis of small molecules

    Article • Bioanalysis, November 2013, Future Science

    Dr Neil Spooner

  24. In-depth study of homogeneity in DBS using two different techniques: results from the EBF DBS-microsampling consortium

    Article • Bioanalysis, September 2013, Future Science

    Dr Neil Spooner, Mr Philip Timmerman

  25. Effect of ambient humidity on the rate at which blood spots dry and the size of the spot produced

    Article • Bioanalysis, August 2013, Future Science

    Dr Neil Spooner

  26. A novel approach to capillary plasma microsampling for quantitative bioanalysis

    Article • Bioanalysis, May 2013, Future Science

    Dr Neil Spooner

  27. A dried blood spot update: still an important bioanalytical technique?

    Article • Bioanalysis, April 2013, Future Science

    Dr Neil Spooner

  28. Dried matrix spot direct analysis: evaluating the robustness of a direct elution technique for use in quantitative bioanalysis

    Article • Bioanalysis, December 2011, Future Science

    Dr Neil Spooner

  29. Method of Applying Internal Standard to Dried Matrix Spot Samples for Use in Quantitative Bioanalysis

    Article • Analytical Chemistry, November 2011, American Chemical Society (ACS)

    Dr Neil Spooner

  30. Quantitative Analysis of Therapeutic Drugs in Dried Blood Spot Samples by Paper Spray Mass Spectrometry: An Avenue to Therapeutic Drug Monitoring

    Article • Journal of the American Society for Mass Spectrometry, June 2011, Springer Science + Business Media

    Dr Neil Spooner

  31. Dried blood spots, pharmacokinetic studies and better medicines for children

    Article • Bioanalysis, April 2011, Future Science

    Dr Neil Spooner

  32. Rapid analysis of dried blood spot samples with sub-2-µm LC–MS/MS

    Article • Bioanalysis, February 2011, Future Science

    Dr Neil Spooner

  33. Dried blood spot sampling for quantitative bioanalysis: time for a revolution?

    Article • Bioanalysis, November 2010, Future Science

    Dr Neil Spooner

  34. Effect of storage conditions on the weight and appearance of dried blood spot samples on various cellulose-based substrates

    Article • Bioanalysis, November 2010, Future Science

    Dr Neil Spooner

  35. A glowing future for dried blood spot sampling

    Article • Bioanalysis, August 2010, Future Science

    Dr Neil Spooner

  36. The effect of hematocrit on assay bias when using DBS samples for the quantitative bioanalysis of drugs

    Article • Bioanalysis, August 2010, Future Science

    Dr Neil Spooner

  37. Study to assess the effect of age of control human and animal blood on its suitability for use in quantitative bioanalytical DBS methods

    Article • Bioanalysis, August 2010, Future Science

    Dr Neil Spooner

  38. Use of DBS sample collection to determine circulating drug concentrations in clinical trials: practicalities and considerations

    Article • Bioanalysis, August 2010, Future Science

    Dr Neil Spooner

  39. Direct Quantitative Bioanalysis of Drugs in Dried Blood Spot Samples Using a Thin-Layer Chromatography Mass Spectrometer Interface

    Article • Analytical Chemistry, December 2009, American Chemical Society (ACS)

    Dr Neil Spooner

  40. Dried Blood Spots as a Sample Collection Technique for the Determination of Pharmacokinetics in Clinical Studies: Considerations for the Validation of a Quantitative Bioanalytical Method

    Article • Analytical Chemistry, February 2009, American Chemical Society (ACS)

    Dr Neil Spooner

  41. Application of dried blood spots combined with HPLC-MS/MS for the quantification of acetaminophen in toxicokinetic studies

    Article • Journal of Chromatography B, July 2008, Elsevier

    Dr Neil Spooner

  42. Reduction of Signal Suppression Effects in ESI-MS Using a Nanosplitting Device

    Article • Analytical Chemistry, December 2001, American Chemical Society (ACS)

    Dr Neil Spooner

  43. Application of Atmospheric Pressure Ionization Time-of-Flight Mass Spectrometry Coupled with Liquid Chromatography for the Characterization of in Vitro Drug Metabolites

    Article • Analytical Chemistry, July 2000, American Chemical Society (ACS)

    Dr Neil Spooner

  44. Biological defunctionalisation of chlorophyll in the aquatic environment II: action of endogenous algal enzymes and aerobic bacteria

    Article • Organic Geochemistry, December 1994, Elsevier

    Dr Neil Spooner

  45. Stable carbon isotopic correlation of individual biolipids in aquatic organisms and a lake bottom sediment

    Article • Organic Geochemistry, June 1994, Elsevier

    Dr Neil Spooner

  46. Biologically mediated defunctionalization of chlorophyll in the aquatic environment—I. Senescence/decay of the diatom Phaeodactylum tricornutum

    Article • Organic Geochemistry, May 1994, Elsevier

    Dr Neil Spooner

  47. THE ANALYSIS OF PLANT STERYL CONJUGATES BY GAS CHROMATOGRAPHY-MASS SPECTROMETRY

    Article • Analytical Sciences, January 1991, Japan Society for Analytical Chemistry

    Dr Neil Spooner

  48. Negative ion ammonia chemical ionization and electron impact ionization mass spectrometric analysis of steryl fatty acyl esters

    Article • Steroids, March 1989, Elsevier

    Dr Neil Spooner

  49. Isolation and characterisation of intact steryl ferulates from seeds

    Article • Journal of Chromatography A, May 1988, Elsevier

    Dr Neil Spooner