All Stories

  1. Vanillin-Isatin Hybrid-Induced MARK4 Inhibition As a Promising Therapeutic Strategy against Hepatocellular Carcinoma
  2. Evaluating Terrestrol A as an Inhibitor Against SARS‐CoV‐2and Invasive Fungal Pathogens: A Comprehensive Computational Analysis
  3. Journey of Von Hippel-Lindau (VHL) E3 ligase in PROTACs design: From VHL ligands to VHL-based degraders
  4. A Comprehensive Multispectroscopic and Computational Analysis of the Interaction between Plant-Based Antiplasmodial Compounds and Bovine Serum Albumin
  5. Synthesis of 1,2,4‐Oxadiazole‐sulfonamide Conjugates and Their Synergistic Effect with Ampicillin as Antimicrobial Agents
  6. Comparative investigation on interaction between potent antimalarials and human serum albumin using multispectroscopic and computational approaches
  7. Microbial Biofilms: Applications, Clinical Consequences, and Alternative Therapies
  8. Synergistic antimicrobial activity, MD simulation studies and crystal structure of natural alcohol motif containing novel substituted cinnamates
  9. Synthesis, spectral characterization of pyrazole derived Schiff base analogs: molecular dynamic simulation, antibacterial and DNA binding studies
  10. Design, Synthesis and Mechanistic Studies of Novel Isatin-Pyrazole Hydrazone Conjugates as Selective and Potent Bacterial MetAP Inhibitors
  11. A multi-spectroscopic and computational simulations study to delineate the interaction between antimalarial drug hydroxychloroquine and human serum albumin
  12. Prefoldin subunit 6 of Plasmodium falciparum binds merozoite surface protein‐1
  13. Mannose 2, 3, 4, 5, 6-O-pentasulfate (MPS): a partial activator of human heparin cofactor II with anticoagulation potential
  14. Structural-activity Relationship of Metallo-aminoquines as Next Generation Antimalarials
  15. Medicinal chemistry updates on quinoline- and endoperoxide-based hybrids with potent antimalarial activity
  16. Metacaspase-3 of Plasmodium falciparum: An atypical trypsin-like serine protease
  17. Design, Synthesis, and Biological Evaluation of Novel Fused Spiro-4H-Pyran Derivatives as Bacterial Biofilm Disruptor
  18. Synthesis of Novel Benzimidazolium Gemini Surfactants and Evaluation of Their Anti-Candida Activity
  19. Synthesis, Antimicrobial Evaluation and In silico Studies of Novel 2,4- disubstituted-1,3-thiazole Derivatives
  20. Antithrombotic potential of esculin 7, 3′, 4′, 5′, 6′-O-pentasulfate (EPS) for its role in thrombus reduction using rat thrombosis model
  21. The Upshot of PI3K Inhibitors as Anticancer Arsenal: A Short Review
  22. Effect of triazole-tryptophan hybrid on the conformation stability of bovine serum albumin
  23. Recent Advances in Cancer Drug Development: Targeting Induced Myeloid Cell Leukemia-1 (Mcl-1) Differentiation Protein
  24. 1,2,3-Triazole–quinazolin-4(3H)-one conjugates: evolution of ergosterol inhibitor as anticandidal agent
  25. Anti-leishmanial and cytotoxic activities of amino acid-triazole hybrids: Synthesis, biological evaluation, molecular docking and in silico physico-chemical properties
  26. Effect of quinoline based 1,2,3-triazole and its structural analogues on growth and virulence attributes of Candida albicans
  27. Synthesis, Antimicrobial Studies, and Docking Simulations of New Bis(4,5‐dihydropyrazole) Derivatives
  28. Efficient synthesis of novel N-substituted 2-carboxy-4-quinolones via lithium bis(trimethylsilyl)amide (LiHMDS)-induced in situ cyclocondensation reaction
  29. Chemically induced degradation of CDK9 by a proteolysis targeting chimera (PROTAC)
  30. Biological Activities and In Silico Physico-Chemical Properties of 1,2,3- Triazoles Derived from Natural Bioactive Alcohols
  31. Experimental and molecular docking investigation on DNA interaction ofN-substituted phthalimides: antibacterial, antioxidant and hemolytic activities
  32. Ruthenium Complexes: An Emerging Ground to the Development of Metallopharmaceuticals for Cancer Therapy
  33. ChemInform Abstract: A Structure Guided Drug-Discovery Approach Towards Identification of Plasmodium Inhibitors
  34. A structure guided drug-discovery approach towards identification of Plasmodium inhibitors
  35. Effect of novel triazole–amino acid hybrids on growth and virulence of Candida species: in vitro and in vivo studies
  36. Evaluation of DNA Binding, Radicals Scavenging and Antimicrobial Studies of Newly Synthesized N-Substituted Naphthalimides: Spectroscopic and Molecular Docking Investigations
  37. Monocyclic β -lactam and unexpected oxazinone formation: synthesis, crystal structure, docking studies and antibacterial evaluation
  38. Synthesis, QSAR and anticandidal evaluation of 1,2,3-triazoles derived from naturally bioactive scaffolds
  39. Diketo acids and their amino acid/dipeptidic analogues as promising scaffolds for the development of bacterial methionine aminopeptidase inhibitors
  40. Polysulfated Trehalose as a Novel Anticoagulant Agent with Dual Mode of Action
  41. Elucidating the specificity of non-heparin-based conformational activators of antithrombin for factor Xa inhibition
  42. Synthesis of N-2-aryl-substituted-1,2,3-triazole Derivatives as Novel Inhibitors of Entamoeba histolytica
  43. Limitations of conventional anticoagulant therapy and the promises of non-heparin based conformational activators of antithrombin
  44. ChemInform Abstract: Synthesis, Spectral Studies and Antiamoebic Activity of New 1-N-Substituted Thiocarbamoyl-3-phenyl-2-pyrazolines.
  45. Synthesis, spectral studies and antiamoebic activity of new 1-N-substituted thiocarbamoyl-3-phenyl-2-pyrazolines
  46. Synthesis and antiamoebic activity of metronidazole thiosemicarbazone analogues
  47. Novel Pd(II) complexes of 1-N-substituted 3-phenyl-2-pyrazoline derivatives and evaluation of antiamoebic activity
  48. Synthesis, characterization and antiamoebic activity of new indole-3-carboxaldehyde thiosemicarbazones and their Pd(II) complexes
  49. Syntheses, characterization and in vitro antiamoebic activity of new Pd(II) complexes with 1-N-substituted thiocarbamoyl-3,5-diphenyl-2-pyrazoline derivatives
  50. Synthesis, Characterization and Antiamoebic Activity of 1-(Thiazolo[4,5-b]quinoxaline-2-yl)-3-phenyl-2-pyrazoline Derivatives.
  51. Synthesis, characterization and antiamoebic activity of 1-(thiazolo[4,5-b]quinoxaline-2-yl)-3-phenyl-2-pyrazoline derivatives
  52. Dioxovanadium(V) and μ-oxo bis[oxovanadium(V)] complexes containing thiosemicarbazone based ONS donor set and their antiamoebic activity
  53. 1-N-Substituted Thiocarbamoyl-3-phenyl-2-pyrazolines: Synthesis and in vitro Antiamoebic Activities.
  54. Synthesis, characterisation, reactivity and in vitro antiamoebic activity of hydrazone based oxovanadium(iv), oxovanadium(v) and µ-bis(oxo)bis{oxovanadium(v)} complexes
  55. Synthesis and Anti-Amoebic Activity of Gold(I), Ruthenium(II), and Copper(II) Complexes of Metronidazole
  56. Synthesis and antiamoebic activity of new oxime ether derivatives containing 2-acetylpyridine/2-acetylfuran
  57. Synthesis and antiamoebic activities of 1-N-substituted cyclised pyrazoline analogues of thiosemicarbazones