All Stories

  1. Reactive intermediates and bioactivation pathways characterization of avitinib by LC–MS/MS: In vitro metabolic investigation

    Article • Journal of Pharmaceutical and Biomedical Analysis, February 2019, Elsevier

    Mohamed Attwa

  2. LC-ESI-MS/MS identification and characterization of ponatinib in vivo phase I and phase II metabolites

    Article • Clinica Chimica Acta, October 2018, Elsevier

    Mohamed Attwa

  3. Investigation of metabolic degradation of new ALK inhibitor: Entrectinib by LC-MS/MS

    Article • Clinica Chimica Acta, October 2018, Elsevier

    Mohamed Attwa

  4. LC–MS/MS reveals the formation of iminium and quinone methide reactive intermediates in entrectinib metabolism: In vivo and in vitro metabolic investigation

    Article • Journal of Pharmaceutical and Biomedical Analysis, October 2018, Elsevier

    Mohamed Attwa

  5. LC-MS/MS reveals the formation of reactive ortho -quinone and iminium intermediates in saracatinib metabolism: Phase I metabolic profiling

    Article • Clinica Chimica Acta, July 2018, Elsevier

    Mohamed Attwa

  6. Development and validation of an HPLC–MS/MS method for the determination of arginine-vasopressin receptor blocker conivaptan in human plasma and rat liver microsomes: application to a metabolic stability study

    Article • Chemistry Central Journal, May 2018, Springer Science + Business Media

    Mohamed Attwa

  7. Characterization of reactive intermediates formation in dacomitinib metabolism and bioactivation pathways elucidation by LC-MS/MS: in vitro phase I metabolic investigation

    Article • RSC Advances, January 2018, Royal Society of Chemistry

    Mohamed Attwa

  8. LC-ESI-MS/MS reveals the formation of reactive intermediates in brigatinib metabolism: elucidation of bioactivation pathways

    Article • RSC Advances, January 2018, Royal Society of Chemistry

    Mohamed Attwa

  9. Isatin-benzoazine molecular hybrids as potential antiproliferative agents: synthesis and in vitro pharmacological profiling

    Article • Drug Design Development and Therapy, August 2017, Dove Medical Press

    Dr Ali S Abdelhameed, Mohamed Attwa, Wagdy Eldehna

  10. Identification and characterization of in vitro phase I and reactive metabolites of masitinib using a LC-MS/MS method: bioactivation pathway elucidation

    Article • RSC Advances, January 2017, Royal Society of Chemistry

    Mohamed Attwa

  11. LC-MS/MS reveals the formation of aldehydes and iminium reactive intermediates in foretinib metabolism: phase I metabolic profiling

    Article • RSC Advances, January 2017, Royal Society of Chemistry

    Mohamed Attwa

  12. Rapid validated liquid chromatographic method coupled with Tandem mass spectrometry for quantification of nintedanib in human plasma

    Article • Tropical Journal of Pharmaceutical Research, December 2016, African Journals Online (AJOL)

    Mohamed Attwa

  13. Liquid chromatographic-mass spectrometric method for determination of drug content uniformity of two commonly used dermatology medications in a split-tablet dosage form

    Article • Tropical Journal of Pharmaceutical Research, July 2016, African Journals Online (AJOL)

    Dr Ali S Abdelhameed, Mohamed Attwa

  14. Pseudo-MS3Approach Using Electrospray Mass Spectrometry (ESI-MS/MS) to Characterize Certain (2E)-2-[3-(1H-Imidazol-1-yl)-1-phenylpropylidene]hydrazinecarboxamide Derivatives

    Article • Journal of Chemistry, January 2014, Hindawi Publishing Corporation

    Dr Ali S Abdelhameed, Mohamed Attwa

  15. Fragmentation Behavior Studies of Chalcones Employing Direct Analysis in Real Time (DART)

    Article • Mass Spectrometry Letters, June 2013, Korean Society for Mass Spectrometry

    Mohamed Attwa

  16. High Throughput Quantitative Bioanalytical LC/MS/MS Determination of Gemifloxacin in Human Urine

    Article • Journal of Chemistry, January 2013, Hindawi Publishing Corporation

    Dr Ali S Abdelhameed, Mohamed Attwa