All Stories

  1. Understanding basic numbers in health and medicine
  2. Methods matter: pilot and feasibility studies in sports medicine
  3. Recurrent sudden unexpected death in infancy: a case series of sibling deaths
  4. Assessing the transparency of informed consent in feasibility and pilot studies: a single-centre quality assurance study protocol
  5. Exploring the implications of different approaches to estimate centre-level adherence using objective adherence data in an adult cystic fibrosis centre – a retrospective observational study
  6. Meeting abstracts from the 5th International Clinical Trials Methodology Conference (ICTMC 2019)
  7. MRI in the diagnosis of fetal developmental brain abnormalities: the MERIDIAN diagnostic accuracy study
  8. Count time series prediction using particle filters
  9. Intravenous antibiotic use and exacerbation events in an adult cystic fibrosis centre: A prospective observational study
  10. Developing new ways of measuring the quality and impact of ambulance service care: the PhOEBE mixed-methods research programme
  11. A Life or “Good Death” Situation? A Worldwide Ecological Study of the National Contexts of Countries That Have and Have Not Implemented Palliative Care
  12. The stepped wedge cluster randomised trial: what it is and when it should be used
  13. A pragmatic behavior-based habit index for adherence to nebulized treatments among adults with cystic fibrosis
  14. Understanding FEV 1 for the purpose of cystic fibrosis registry comparisons: Does bias in annual review FEV 1 affect between‐centre comparison within the UK? An analysis of registry data
  15. Cluster randomised trials
  16. Does evidence support the high expectations placed in precision medicine? A bibliographic review
  17. Reporting of stepped wedge cluster randomised trials: extension of the CONSORT 2010 statement with explanation and elaboration
  18. Emergency hospital care for adults with suspected seizures in the NHS in England 2007–2013: a cross-sectional study
  19. A randomised controlled trial is not a pilot trial simply because it uses a surrogate endpoint
  20. Sample Sizes for Clinical, Laboratory and Epidemiology Studies
  21. The DiPEP study: an observational study of the diagnostic accuracy of clinical assessment, D-dimer and chest x-ray for suspected pulmonary embolism in pregnancy and postpartum
  22. The importance of data issues when comparing cystic fibrosis registry outcomes between countries: Are annual review FEV1 in the UK only collected when subjects are well?
  23. Role of habit in treatment adherence among adults with cystic fibrosis
  24. Basic Design Considerations
  25. Binary Outcomes
  26. Cluster Designs
  27. Confidence Intervals
  28. Continuous Outcomes
  29. Cumulative References
  30. Feasibility and Pilot Studies
  31. Front Matter
  32. Further Design Considerations
  33. Genomic Targets and Dose-Finding
  34. Index
  35. More than Two Groups Designs
  36. Non-Inferiority and Equivalence
  37. Observer Agreement Studies
  38. Ordered Categorical Outcomes
  39. Paired Binary, Ordered Categorical and Continuous Outcomes
  40. Rate Outcomes
  41. Reference Intervals and Receiver Operating Curves
  42. Repeated Outcome Measures
  43. Sample Size Software
  44. Stepped Wedge Designs
  45. Supplemental Images
  46. Survival Time Outcomes
  47. The Correlation Coefficient
  48. Therapeutic Exploratory Trials
  49. Therapeutic Exploratory Trials
  50. Do cystic fibrosis centres with the lowest FEV1 still use the least amount of intravenous antibiotics? A registry-based comparison of intravenous antibiotic use among adult CF centres in the UK
  51. Family lifestyle dynamics and childhood obesity: evidence from the millennium cohort study
  52. Response to Comment on Novodvorsky et al. Diurnal Differences in Risk of Cardiac Arrhythmias During Spontaneous Hypoglycemia in Young People With Type 1 Diabetes. Diabetes Care 2017;40:655–662
  53. Evidence against precision medicine?
  54. 1800 Uk unscheduled admissions for adults with suspected seizures
  55. Use of MRI in the Diagnosis of Fetal Brain Abnormalities in Utero (MERIDIAN)
  56. Predictors of intravenous antibiotic use among adults with cystic fibrosis (CF)
  57. Change in diagnostic confidence brought about by using in utero MRI for fetal structural brain pathology: analysis of the MERIDIAN cohort
  58. Use of MRI in the Diagnosis of Fetal Brain Abnormalities in Utero (MERIDIAN)
  59. Reply
  60. A cluster randomised trial, cost-effectiveness analysis and psychosocial evaluation of insulin pump therapy compared with multiple injections during flexible intensive insulin therapy for type 1 diabetes: the REPOSE Trial
  61. Relative effectiveness of insulin pump treatment over multiple daily injections and structured education during flexible intensive insulin treatment for type 1 diabetes: cluster randomised trial (REPOSE)
  62. Minimum number of clusters and comparison of analysis methods for cross sectional stepped wedge cluster randomised trials with binary outcomes: A simulation study
  63. An empirical method to cluster objective nebulizer adherence data among adults with cystic fibrosis
  64. Severe acute malnutrition in children aged under 5 years can be successfully managed in a non‐emergency routine community healthcare setting in Ghana
  65. Informing efficient randomised controlled trials: exploration of challenges in developing progression criteria for internal pilot studies
  66. Use of MRI in the diagnosis of fetal brain abnormalities in utero (MERIDIAN): a multicentre, prospective cohort study
  67. What is propensity score modelling?
  68. Catheter insertion techniques for improving catheter function and clinical outcomes in peritoneal dialysis patients
  69. Determinants of objective adherence to nebulised medications among adults with cystic fibrosis: an exploratory mixed methods study comparing low and high adherers
  70. Chronic obstructive pulmonary disease in Welsh slate miners
  71. CONSORT 2010 statement: extension to randomised pilot and feasibility trials
  72. CONSORT 2010 statement: extension to randomised pilot and feasibility trials
  73. The effects of breastfeeding on childhood BMI: a propensity score matching approach
  74. Time Series Regression
  75. Acute effects of aircraft noise on cardiovascular admissions – an interrupted time-series analysis of a six-day closure of London Heathrow Airport caused by volcanic ash
  76. Erratum to: Methods and processes for development of a CONSORT extension for reporting pilot randomized controlled trials
  77. Air Pollution and Subtypes, Severity and Vulnerability to Ischemic Stroke—A Population Based Case-Crossover Study
  78. Stepped wedge cluster randomised trials: a review of the statistical methodology used and available
  79. 268 Rescue and prevention in cystic fibrosis: an exploration of the impact of adherence to preventative nebulised therapy upon subsequent rescue therapy with IV antibiotics in adults with CF
  80. WS23.3 Rescue therapy within the UK CF registry: an exploration of the predictors of IV antibiotic use amongst adults with cystic fibrosis
  81. Methods and processes for development of a CONSORT extension for reporting pilot randomized controlled trials
  82. Accurate reporting of adherence to inhaled therapies in adults with cystic fibrosis: methods to calculate normative adherence
  83. Defining Feasibility and Pilot Studies in Preparation for Randomised Controlled Trials: Development of a Conceptual Framework
  84. Defining feasibility and pilot studies in preparation for randomised controlled trials: using consensus methods and validation to develop a conceptual framework
  85. Improving the reporting of randomised pilot and feasibility studies: a consort statement extension
  86. P274 Moving from rescue to prevention: real world evidence of reduction in IV antibiotic requirement following improvement in adherence to maintenance nebulised treatment in an adult cystic fibrosis centre: Abstract P274 Table 1
  87. Lowering bed occupancy: a life-saving intervention?
  88. Who gains clinical benefit from using insulin pump therapy? A qualitative study of the perceptions and views of health professionals involved in the Relative Effectiveness of Pumps over MDI and Structured Education (REPOSE) trial
  89. The mortality and hospitalization rates associated with the long interdialytic gap in thrice-weekly hemodialysis patients
  90. Estimating the sample size for a pilot randomised trial to minimise the overall trial sample size for the external pilot and main trial for a continuous outcome variable
  91. Sample size calculations for the design of cluster randomized trials: A summary of methodology
  92. The BMJ report on mortality cuts in hospitals put into special measures in 2013 is misleading
  93. Mortality of babies enrolled in a community-based support programme: CONI PLUS (Care of Next Infant Plus)
  94. Secondary analysis and literature review of community rehabilitation and intermediate care: an information resource
  95. A cluster randomized controlled non-inferiority trial of 5-day Dose Adjustment for Normal Eating (DAFNE) training delivered over 1 week versus 5-day DAFNE training delivered over 5 weeks: the DAFNE 5 × 1-day trial
  96. Perceptions and experiences of using automated bolus advisors amongst people with type 1 diabetes: A longitudinal qualitative investigation
  97. Improving management of type 1 diabetes in the UK: the Dose Adjustment For Normal Eating (DAFNE) programme as a research test-bed. A mixed-method analysis of the barriers to and facilitators of successful diabetes self-management, a health economic ana...
  98. Adjusting for treatment switching in randomised controlled trials – A simulation study and a simplified two-stage method
  99. Self-monitoring of blood glucose versus self-monitoring of urine glucose in adults with newly diagnosed Type 2 diabetes receiving structured education: a cluster randomized controlled trial
  100. The Potential Value of Ongoing Support In Type-1 Diabetes Mellitus With Dafneplus: Exploratory Pre-Trial Cost-Effectiveness Analysis On Proposed Trial End-Point Target For 12-Month Hba1c Improvement
  101. A hazard ratio was estimated by a ratio of median survival times, but with considerable uncertainty
  102. Clinical Signals
  103. Pulmonary Medicine
  104. Time Series Regression
  105. The Relative Effectiveness of Pumps Over MDI and Structured Education (REPOSE): study protocol for a cluster randomised controlled trial
  106. Challenges of cluster randomized trials
  107. Pilot and feasibility studies: Is there a difference from each other and from a randomised controlled trial?
  108. PERITONEAL DIALYSIS 1
  109. How to Design, Analyse and Report Cluster Randomised Trials in Medicine and Health Related Research
  110. Substantial reductions in the number of diabetic ketoacidosis and severe hypoglycaemia episodes requiring emergency treatment lead to reduced costs after structured education in adults with Type 1 diabetes
  111. Estimated Albumin Excretion Rate Versus Urine Albumin-Creatinine Ratio for the Estimation of Measured Albumin Excretion Rate: Derivation and Validation of an Estimated Albumin Excretion Rate Equation
  112. Adjusting Survival Time Estimates to Account for Treatment Switching in Randomized Controlled Trials—an Economic Evaluation Context
  113. Impact of a GP-led walk-in centre on NHS emergency departments
  114. Outdoor air pollution, subtypes and severity of ischemic stroke – a small-area level ecological study
  115. Cluster Randomized Trials
  116. Prognostic Value of Cardiovascular Magnetic Resonance Imaging Measurements Corrected for Age and Sex in Idiopathic Pulmonary Arterial Hypertension
  117. A Guide to Adjusting Survival Time Estimates to Account for Treatment Switching in Randomised Controlled Trials
  118. Definition and reporting of pilot and feasibility studies
  119. Direct risk standardisation: a new method for comparing casemix adjusted event rates using complex models
  120. Mortality indicators used to rank hospital performance
  121. What do hospital mortality rates tell us about quality of care?: Table 1
  122. Variation in centre-specific survival in patients starting renal replacement therapy in England is explained by enhanced comorbidity information from hospitalization data
  123. Pilot study of a brief intervention based on the theory of planned behaviour and self-identity to increase chlamydia testing among young people living in deprived areas
  124. ABR in newborns: Effects of electrode configuration, stimulus rate, and EEG rejection levels on test efficiency
  125. Good Practice Guidelines for the use of Statistical Regression Models in Economic Evaluations
  126. Did hospital mortality in England change from 2005 to 2010? A retrospective cohort analysis
  127. Patients’ experience and satisfaction with GP led walk-in centres in the UK; a cross sectional study
  128. GP-led walk-in centre in the UK: another way for urgent healthcare provision
  129. Doing clinical trials large enough to achieve adequate reductions in uncertainties about treatment effects
  130. How to reduce the risk of failing to reach recruitment targets: lessons learnt from a pump pilot trial
  131. Disparities in Healthcare Utilisation Rates for Aboriginal and Non-Aboriginal Albertan Residents, 1997–2006: A Population Database Study
  132. The 5x1 DAFNE study protocol: a cluster randomised trial comparing a standard 5 day DAFNE course delivered over 1 week against DAFNE training delivered over 1 day a week for 5 consecutive weeks
  133. Home ovulation tests and stress in women trying to conceive: a randomized controlled trial
  134. Rapid-Throughput Skeletal Phenotyping of 100 Knockout Mice Identifies 9 New Genes That Determine Bone Strength
  135. Tutorial in biostatistics: sample sizes for parallel group clinical trials with binary data
  136. Cognitive behavioural intervention for adults with anxiety complications of asthma: Prospective randomised trial
  137. Improved Biomedical and Psychological Outcomes 1 Year After Structured Education in Flexible Insulin Therapy for People With Type 1 Diabetes: The U.K. DAFNE experience
  138. Effectiveness of a diabetes education and self management programme (DESMOND) for people with newly diagnosed type 2 diabetes mellitus: three year follow-up of a cluster randomised controlled trial in primary care
  139. Does self monitoring of blood glucose as opposed to urinalysis provide additional benefit in patients newly diagnosed with type 2 diabetes receiving structured education? The DESMOND SMBG randomised controlled trial protocol
  140. Developing a summary hospital mortality index: retrospective analysis in English hospitals over five years
  141. The development and validation of a clinical prediction model to determine the probability of MODY in patients with young-onset diabetes
  142. Clinical effectiveness of a patient decision aid to improve decision quality and glycaemic control in people with diabetes making treatment choices: a cluster randomised controlled trial (PANDAs) in general practice
  143. Chapter 13 The Linkage of Incident Renal Replacement Therapy Patients in England (2002–2006) to Hospital Episodes and National Mortality Data: Improved Demography and Hospitalisation Data in Patients Undergoing Renal Replacement Therapy
  144. A pragmatic quasi-experimental multi-site community intervention trial evaluating the impact of Emergency Care Practitioners in different UK health settings on patient pathways (NEECaP Trial)
  145. Seasonality of medical contacts in school-aged children with asthma: Association with school holidays
  146. Outdoor Air Pollution and Incidence of Ischemic and Hemorrhagic Stroke: A Small-Area Level Ecological Study
  147. Reprinted Article “Carotid Artery Plaque Composition—Relationship to Clinical Presentation and Ultrasound B-mode Imaging”
  148. Long-term Outcomes of Patients With Autoimmune Hepatitis Managed at a Nontransplant Center
  149. Epidemiology of scabies prevalence in the U.K. from general practice records
  150. Sixth International French Society of Statistics meeting on statistical methods in biopharmacy: Recent advances and trends in statistics as applied to clinical trials
  151. Comments on ‘The potential for bias in the reporting of industry sponsored clinical trials’ by Stephen Pyke et al. and ‘Proposed best practice for statisticians in the reporting and publication of pharmaceutical industry sponsored clinical trials’ by Jame
  152. Possible Evidence for a Fall in the Prevalence of High-Functioning Pervasive Developmental Disorder with Age?
  153. Authors' reply
  154. Evaluation of triage methods used to select patients with suspected pandemic influenza for hospital admission: cohort study
  155. Delivering the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes: cost effectiveness analysis
  156. Statistical issues in Primary Care
  157. What is a pilot or feasibility study? A review of current practice and editorial policy
  158. Assessing quality of care from hospital case notes: comparison of reliability of two methods
  159. A statistician on a NICE committee
  160. Trials in primary care: statistical issues in the design, conduct and evaluation of complex interventions
  161. Impact of Outdoor Air Pollution on Survival After Stroke: Population-Based Cohort Study
  162. Comparison of case note review methods for evaluating quality and safety in health care
  163. Do South Asian women with PCOS have poorer health-related quality of life than Caucasian women with PCOS? A comparative cross-sectional study
  164. A randomized, controlled dose-ranging study of risedronate in children with moderate and severe osteogenesis imperfecta
  165. Cluster Randomised Trials by HAYES, R. J. and MOULTON, L. H.
  166. Evaluation of the impact of a health forecast alert service on admissions for chronic obstructive pulmonary disease in Bradford and Airedale
  167. Modified-Release Hydrocortisone to Provide Circadian Cortisol Profiles
  168. Sample Size Tables for Clinical Studies
  169. A RANDOMISED CONTROLLED:TRIAL OF DIFFERENT INTENSITIES OF PHYSIOTHERAPY AND DIFFERENT GOAL-SETTING PROCEDURES IN 44 CHILDREN WITH CEREBRAL PALSY
  170. Misinterpreting P-Values In Research
  171. Recurrence rates for sudden infant death syndrome (SIDS): the importance of risk stratification
  172. Evaluating the efficacy of acupuncture in defined aspects of stroke recovery
  173. How common is repeat sudden infant death syndrome?
  174. Optimal Thresholds, Linear or Nonlinear Relationships of Fracture Risk Reduction With Therapy
  175. Effectiveness of the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes: cluster randomised controlled trial
  176. Rationale, design, and baseline characteristics for a large international trial of cardiovascular disease prevention in people with dysglycemia: The ORIGIN Trial (Outcome Reduction with an Initial Glargine Intervention)
  177. Impact of a Restraint Training Module on Paramedic Students' Likelihood to Use Restraint Techniques
  178. Fundamentals of Clinical Research: Bridging Medicine, Statistics and Operations by Antonella Bacchieri, Giovanni Della Cioppa
  179. Relationship of Early Changes in Bone Resorption to the Reduction in Fracture Risk With Risedronate: Review of Statistical Analysis
  180. Contamination in trials of educational interventions
  181. Predicting where future means will lie based on the results of the current trial
  182. Invalid methods
  183. Impact of NHS walk-in centres on primary care access times: ecological study
  184. Risk of hypoglycaemia in types 1 and 2 diabetes: effects of treatment modalities and their duration
  185. Combining Growth Hormone Releasing Hormone-Arginine and Synacthen Testing Diminishes the Cortisol Response
  186. Implementing referral guidelines: lessons from a negative outcome cluster randomised factorial trial in general practice
  187. Randomised controlled trial of a short course of traditional acupuncture compared with usual care for persistent non-specific low back pain
  188. Language Ability after Early Detection of Permanent Childhood Hearing Impairment
  189. The effect of helium and oxygen on exercise performance in COPD: A randomised crossover trial
  190. The Effect of Helium and Oxygen on Exercise Performance in Chronic Obstructive Pulmonary Disease
  191. Cost-effectiveness and cost-utility of tricyclic antidepressants, selective serotonin reuptake inhibitors and lofepramine
  192. Editorial
  193. Editorial
  194. Statistics at Square Two
  195. Developments in cluster randomized trials andStatistics in Medicine
  196. Non-inferiority trials: continued advancements in concepts and methodology (special papers for the 25th anniversary ofStatistics in Medicine25(7))
  197. The Mann–Whitney statistic: continuous use and discovery
  198. Editorial
  199. Editorial
  200. Editorial
  201. Hypopituitary patients prefer a touch-screen to paper quality of life questionnaire
  202. Do ‘food deserts’ influence fruit and vegetable consumption?—a cross-sectional study
  203. Outdoor air pollution, mortality, and hospital admissions from coronary heart disease in Sheffield, UK: a small-area level ecological study
  204. Life and death decisions: A statistician on a data monitoring and ethics committee
  205. Universal newborn screening for permanent childhood hearing impairment: an 8-year follow-up of a controlled trial
  206. Longer term clinical and economic benefits of offering acupuncture care to patients with chronic low back pain
  207. Clinical Signals
  208. Pulmonary Medicine
  209. Time Series Regression
  210. A 24 year cohort study of mortality in slate workers in North Wales
  211. A randomised controlled trial to compare the cost-effectiveness of tricyclic antidepressants, selective serotonin reuptake inhibitors and lofepramine
  212. Intraclass correlation coefficient and outcome prevalence are associated in clustered binary data
  213. Design of Studies for Medical Research
  214. Editorial
  215. Surrogate markers: back to the future
  216. Assurance in clinical trial design
  217. Restructuring the editorial board
  218. The use of bootstrap methods for estimating sample size and analysing health-related quality of life outcomes
  219. Outdoor Air Pollution and Stroke in Sheffield, United Kingdom: A Small-Area Level Geographical Study
  220. A survey of statistics in three UK general practice journal
  221. BMJ statistical errors
  222. Patterns of intra-cluster correlation from primary care research to inform study design and analysis
  223. Smoking and Parkinson's disease: Systematic review of prospective studies
  224. Extending CONSORT to include cluster trials
  225. Acupuncture for low back pain: traditional diagnosis and treatment of 148 patients in a clinical trial
  226. Statistical aspects
  227. Combination of APACHE-II score and an obesity score (APACHE-O) for the prediction of severe acute pancreatitis
  228. The Armitage lectures
  229. Editorial
  230. Parkinson’s Disease Protects Against Smoking?
  231. Sensitivity analysis of common statistical models used to study the short-term effects of air pollution on health
  232. Geographical and organisational variation in the structure of primary care services: implications for study design
  233. Statistics in Medicine moves into online submission
  234. Effect on endometrium of long term treatment with continuous combined oestrogen-progestogen replacement therapy: follow up study
  235. Longer-Term Clinical and Economic Benefits of Offering Acupuncture to Patients with Chronic Low Back Pain Assessed as Suitable for Primary Care Management – 3 Month Clinical Outcomes from a Controlled Trial of 241 Patients
  236. Epidemiology research
  237. Discussion on the paper by Spiegelhalter, Aylin, Best, Evans and Murray
  238. A review of ordinal regression models applied on health-related quality of life assessments
  239. La enfermedad de Parkinson y el tabaco: coherencia y plausibilidad
  240. Randomized, Controlled Trial of Acetazolamide and Furosemide in Posthemorrhagic Ventricular Dilation in Infancy: Follow-Up at 1 Year
  241. Atmospheric pressure and sudden infant death syndrome in Cook County, Chicago
  242. The Wessex Recent In-Patient Suicide Study, 2
  243. The Wessex Recent In-Patient Suicide Study, 1
  244. The Safety and Effectiveness of the Le Fort I Approach to Removing Central Skull Base Lesions
  245. Randomized controlled trial of physiotherapy in 56 children with cerebral palsy followed for 18 months
  246. DESIGN AND ANALYSIS OF TRIALS WITH QUALITY OF LIFE AS AN OUTCOME: A PRACTICAL GUIDE
  247. Preface
  248. The endometrial response to sequential and continuous combined oestrogen-progestogen replacement therapy
  249. Sample sizes for cancer trials where Health Related Quality of Life is the primary outcome
  250. The Wessex Head Injury Matrix (WHIM) main scale: a preliminary report on a scale to assess and monitor patient recovery after severe head injury
  251. Causality and temporality in the study of short-term effects of air pollution on health
  252. Cluster randomized trials in general (family) practice research
  253. Effects of a clinical-practice guideline and practice-based education on detection and outcome of depression in primary care: Hampshire Depression Project randomised controlled trial
  254. Statistical review by research ethics committees
  255. Effect of antidepressant drug counselling and information leaflets on adherence to drug treatment in primary care: randomised controlled trial
  256. Modelling influenza epidemics in the relation between black smoke and total mortality. A sensitivity analysis
  257. A GEE moving average analysis of the relationship between air pollution and mortality for asthma in Barcelona, Spain
  258. Patient centred care of diabetes in general practice
  259. Longer term clinical and economic benefits of offering acupuncture to patients with chronic low back pain assessed as suitable for primary care management
  260. ESTIMATING SAMPLE SIZES FOR CONTINUOUS, BINARY, AND ORDINAL OUTCOMES IN PAIRED COMPARISONS: PRACTICAL HINTS
  261. Diabetes Care from Diagnosis: Effects of training in patient-centred care on beliefs, attitudes and behaviour of primary care professionals
  262. Systemic effects of inhaled corticosteroids on growth and bone turnover in childhood asthma: a comparison of fluticasone with beclomethasone
  263. Controlled trial of universal neonatal screening for early identification of permanent childhood hearing impairment
  264. Choosing between randomised and non-randomised studies: a systematic review
  265. Randomised controlled trial of patient centred care of diabetes in general practice: impact on current wellbeing and future disease risk
  266. International randomised controlled trial of acetazolamide and furosemide in posthaemorrhagic ventricular dilatation in infancy
  267. Sample size calculations for paired or matched ordinal data
  268. Investigation of the effect of occult invasive cancer on progress towards successful cervical screening
  269. Clinical significance not statistical significance: a simple Bayesian alternative to p values
  270. Duration of growth suppressive effects of regular inhaled corticosteroids
  271. Trends in asthma
  272. Quality of life and patient preference for sequential versus continuous combined HRT: the UK Kliofem® multicenter study experience
  273. Association between nonadministration of subconjunctival cefuroxime and postoperative endophthalmitis
  274. Half-life of intracameral gentamicin after phacoemulsification
  275. Age specific trends in asthma mortality in England and Wales, 1983-95: results of an observational study
  276. Prevalence of inverted and non-protractile nipples in antenatal women who intend to breast-feed
  277. Circaseptennial rhythm is an artefact
  278. Women Married to Men with Myocardial Infarction are at Increased Risk of Coronary Heart Disease
  279. Double blind placebo controlled trial of nebulised budesonide for croup   Commentary
  280. Using aspects of study design in sample size estimation
  281. Does dietary intake of vitamins C and E influence lung function in older people?
  282. The relationship between upper respiratory infections and hospital admissions for asthma: a time-trend analysis.
  283. Spectral analysis of clinical signals: an interface between medical statisticians and medical engineers
  284. Sample sizes for studies using the short form 36 (SF-36)
  285. Estimating sample sizes for binary, ordered categorical, and continuous outcomes in two group comparisons
  286. Statistics would make Stalin proud
  287. Good long-term outcome following surgical repair of post-infarction ventricular septal defect
  288. Study quoted had flawed design
  289. Assessing the Adequacy of Standard Clinical Definitions of Important Vaginal Bleeding Disorders
  290. Posture, blood velocity in common femoral vein, and prophylaxis of venous thromboembolism
  291. P values are still useful
  292. Commentary: n of 1 trials may be useful for informed decision making
  293. Is the timing of withdrawal bleeding a guide to endometrial safety during sequential oestrogen-progestagen replacement therapy?
  294. Coping with extra poisson variability in the analysis of factors influencing vaginal ring expulsions
  295. Asthma at the interface: bridging the gap between general practice and a district general hospital.
  296. Statistics in medicine: Citations of papers in the first ten years
  297. Does clinical experience with a treatment regimen affect survival of lung cancer patients? An analysis based on consecutive randomized trials of the medical research council in small cell and non-small cell tumours
  298. Time Series Regression for Counts: An Investigation into the Relationship between Sudden Infant Death Syndrome and Environmental Temperature
  299. Sample size in audit.
  300. Determinants of contraceptive method choice after first delivery, before first abortion, and after first abortion in East China
  301. A review of behavioural assessment scales for monitoring recovery in and after coma with pilot data on a new scale of visual awareness
  302. Box-plots
  303. Management of feverish children at home.
  304. The Interaction between Immunoglobulin E and Smoking in Airflow Obstruction in the Elderly
  305. Randomised controlled trial of breast shells and Hoffman's exercises for inverted and non-protractile nipples.
  306. Effects of self-help post-myocardial-infarction rehabilitation on psychological adjustment and use of health services
  307. Adjusting for baseline: Chamge or percentage change
  308. An Evaluation of a Nurse-run Asthma Clinic in General Practice Using an Attitudes and Morbidity Questionnaire
  309. Assessment of the psychological impact of a breast screening programme
  310. Magnesium and chronic fatigue syndrome
  311. Red blood cell magnesium and chronic fatigue syndrome
  312. Coping with extra poisson variability in the analysis of factors influencing vaginal ring expulsions
  313. Sudden infant deaths and cold weather: was the rise in infant mortality in 1986 in England and Wales due to the weather?
  314. Heights and Weights of Children in Ladakh, North India
  315. Response
  316. Comparison of audible sound transmission with ultrasound in screening for congenital dislocation of the hip
  317. Prognostic index for the development of liver metastases in patients with colorectal cancer
  318. Analysis of serial measurements in medical research: Authors' reply
  319. Does anonymity increase response rate in postal questionnaire surveys about sensitive subjects? A randomised trial.
  320. Analysis of serial measurements in medical research.
  321. Sudden infant death syndrome and environmental temperature: further evidence for a time‐lagged relationship (for editorial comment, see page 361)
  322. Is there an increased risk of twinning after discontinuation of the oral contraceptive pill?
  323. Relief care and risk of death in psychogeriatric patients.
  324. Methotrexate dosage in patients aged over 50 with psoriasis.
  325. Letters to the editor
  326. Effect of transdermal glyceryl trinitrate on the survival of peripheral intravenous infusions: A double-blind prospective clinical study
  327. Exercise levels and resting pulse rate in the community.
  328. Further evidence for the effect of passive smoking on neonates.
  329. Assessing changes in vaginal bleeding patterns in contracepting women
  330. Statistics in Medicine: Calculating confidence intervals for some non-parametric analyses
  331. Twenty years' screening for cancer of the uterine cervix in Great Britain, 1964-84: further evidence for its ineffectiveness.
  332. SUGAR AND HEALTH
  333. The success of in situ vein grafting: Early results in comparison with the reversed vein technique
  334. Public knowledge about AIDS increasing.
  335. Sudden infant death syndrome and environmental temperature: an analysis using vital statistics.
  336. Predictive power of progesterone receptor status in early breast carcinoma
  337. Public knowledge of AIDS and the DHSS advertisement campaign: Authors' reply
  338. Public knowledge of AIDS and the DHSS advertisement campaign.
  339. Increased risk of sudden infant death syndrome in older infants at weekends.
  340. Specific causes of death in miners and ex-miners of the Rhondda Fach 1950-80.
  341. Gastric cancer in a south Wales valley.
  342. Respiratory disability in ex-flax workers.
  343. Use of check lists in assessing the statistical content of medical studies.
  344. A comparison of plating and traction in the treatment of tibial shaft fractures
  345. Mortality of men in the Rhondda Fach 1950-80.
  346. AZATHIOPRINE AND CYCLOSPORIN: DIFFERENT TISSUE MATCHING CRITERIA NEEDED?
  347. Multiplicative and additive models with external controls in a cohort study of cancer mortality
  348. Peer review at work
  349. Peer review at work
  350. Can general practitioners influence exercise habits? Controlled trial.
  351. Mortality, haemoglobin level and haematocrit in women
  352. Chest pain in women: a study of prevalence and mortality follow up in south Wales.
  353. Migraine, headache, and survival in women
  354. Trials of live attenuated influenza virus vaccine in patients with chronic obstructive airways disease
  355. Migraine, headache, and survival in women.
  356. HIGH BLOOD PRESSURE AND MORTALITY IN THE ELDERLY
  357. The analysis using genstat of anaemia, sugar intake and Quetelet's index as prognostic indicators in women
  358. Spectral Analysis Applied To Physiological Signals In Human Subjects
  359. IRREGULAR OPACITIES IN COALWORKERS' PNEUMOCONIOSIS—CORRELATION WITH PULMONARY FUNCTION AND PATHOLOGY
  360. Relationship between type of simple coalworkers' pneumoconiosis and lung function. A nine-year follow-up study of subjects with small rounded opacities.
  361. Aetiological factors in rickets of prematurity.
  362. Cardiac frequency during stepping exercise and during treadmill walking as guides to the Harvard Pack Index of physical fitness
  363. A note on the sampling of a point process for spectral analysis
  364. A Survey of Statistical Work on the Mackenzie River Series of Annual Canadian Lynx Trappings for the Years 1821-1934 and a New Analysis
  365. A Review of the Use of the Main Quality of Life Measures, and Sample Size Determination for Quality of Life Measures, Particularly in Cancer Clinical Trials
  366. Answers to Exercises
  367. Appendix 1: Exponentials and Logarithms
  368. Appendix 2: Maximum Likelihood and Significance Tests
  369. Appendix 3: Bootstrapping and Variance Robust Standard Errors
  370. Appendix 4: Bayesian Methods
  371. Frontmatter
  372. Glossary
  373. Index
  374. Logistic Regression
  375. Models, Tests and Data
  376. Multiple Linear Regression
  377. Other Models
  378. Random Effects Models
  379. Survival Analysis