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  1. Recent advances in multimodal imaging of infections: research highlights using Nuclear-Optical imaging

    Article • European Journal of Pediatrics, January 2026, Springer Science + Business Media

    Dr. Mick Welling

  2. Synthetic Human Lactoferrin Peptide hLF(1-11) Shows Antifungal Activity and Synergism with Fluconazole and Anidulafungin Towards Candida albicans and Various Non-Albicans Candida Species, Including Candidozyma auris

    Article • Antibiotics, July 2025, MDPI AG

    Dr. Mick Welling

  3. Potential health benefits of lactoferrin and derived peptides – how to qualify as a medical device?

    Article • Critical Reviews in Microbiology, February 2025, Taylor & Francis

    Dr. Mick Welling

  4. Evaluation of [68Ga]Ga-DOTA-AeK as a Potential Imaging Tool for PET Imaging of Cell Wall Synthesis in Bacterial Infections

    Article • Pharmaceuticals, August 2024, MDPI AG

    Dr. Mick Welling

  5. Combinatory Use of hLF(1-11), a Synthetic Peptide Derived from Human Lactoferrin, and Fluconazole/Amphotericin B against Malassezia furfur Reveals a Synergistic/Additive Antifungal Effect

    Article • Antibiotics, August 2024, MDPI AG

    Dr. Mick Welling

  6. hHEPATO-Cy5, a Bimodal Tracer for Image-Guided Hepatobiliary Surgery

    Article • Journal of Nuclear Medicine, July 2024, Society of Nuclear Medicine

    Dr. Mick Welling

  7. Biodistribution of Radioactively Labeled Splice Modulating Antisense Oligonucleotides After Intracerebroventricular and Intrathecal Injection in Mice

    Article • Nucleic Acid Therapeutics, February 2024, SAGE Publications

    Dr. Mick Welling

  8. Insights into Peptidoglycan-Targeting Radiotracers for Imaging Bacterial Infections: Updates, Challenges, and Future Perspectives

    Article • ACS Infectious Diseases, January 2024, American Chemical Society (ACS)

    Dr. Mick Welling

  9. The Development and Validation of Radiopharmaceuticals Targeting Bacterial Infection

    Article • Journal of Nuclear Medicine, September 2023, Society of Nuclear Medicine

    Dr. Mick Welling

  10. Microspheres as a Carrier System for Therapeutic Embolization Procedures: Achievements and Advances

    Article • Journal of Clinical Medicine, January 2023, MDPI AG

    Dr. Mick Welling

  11. A radio- and fluorescently labelled tracer for imaging and quantification of bacterial infection on orthopaedic prostheses

    Article • Bone and Joint Research, January 2023, Bone & Joint

    Dr. Mick Welling

  12. Feasibility of fluorescence imaging at microdosing using a hybrid PSMA tracer during robot-assisted radical prostatectomy in a large animal model

    Article • EJNMMI Research, March 2022, Springer Science + Business Media

    Dr. Mick Welling

  13. Advancing intraoperative magnetic tracing using 3D freehand magnetic particle imaging

    Article • International Journal of Computer Assisted Radiology and Surgery, July 2021, Springer Science + Business Media

    Dr. Mick Welling

  14. Cyclodextrin/Adamantane-Mediated Targeting of Inoculated Bacteria in Mice

    Article • Bioconjugate Chemistry, February 2021, American Chemical Society (ACS)

    Dr Wiep Klaas Smits, Dr. Mick Welling

  15. The helminth glycoprotein omega‐1 improves metabolic homeostasis in obese mice through type 2 immunity‐independent inhibition of food intake

    Article • The FASEB Journal, January 2021, Wiley

    Dr. Mick Welling

  16. Interventional nuclear medicine: “click” chemistry as an in vivo targeting strategy for imaging microspheres and bacteria

    Article • Biomaterials Science, January 2021, Royal Society of Chemistry

    Dr. Mick Welling

  17. Evaluation of asymmetric orthogonal cyanine fluorophores

    Article • Dyes and Pigments, December 2020, Elsevier

    Dr. Mick Welling

  18. Imaging Bacteria with Radiolabelled Probes: Is It Feasible?

    Article • Journal of Clinical Medicine, July 2020, MDPI AG

    Alberto Signore, Dr. Mick Welling

  19. A Supramolecular Platform Technology for Bacterial Cell Surface Modification

    Article • ACS Infectious Diseases, May 2020, American Chemical Society (ACS)

    Dr. Mick Welling

  20. Extending the Hybrid Surgical Guidance Concept With Freehand Fluorescence Tomography

    Article • IEEE Transactions on Medical Imaging, January 2020, Institute of Electrical & Electronics Engineers (IEEE)

    Dr. Mick Welling

  21. Hybrid Tracers Based on Cyanine Backbones Targeting Prostate-Specific Membrane Antigen: Tuning Pharmacokinetic Properties and Exploring Dye–Protein Interaction

    Article • Journal of Nuclear Medicine, September 2019, Society of Nuclear Medicine

    Dr. Mick Welling

  22. Hybrid detection modalities for image-guided surgery

    Article • Expert Review of Medical Devices, July 2019, Taylor & Francis

    Dr. Mick Welling

  23. Click Chemistry in the Design and Production of Hybrid Tracers

    Article • ACS Omega, July 2019, American Chemical Society (ACS)

    Dr. Mick Welling

  24. Multimodal Tracking of Controlled Staphylococcus aureus Infections in Mice

    Article • ACS Infectious Diseases, April 2019, American Chemical Society (ACS)

    Dr. Mick Welling, Dr Wiep Klaas Smits

  25. Fluorescent imaging of bacterial infections and recent advances made with multimodal radiopharmaceuticals

    Article • Clinical and Translational Imaging, April 2019, Springer Science + Business Media

    Dr. Mick Welling, Dr Wiep Klaas Smits

  26. An update on radiotracer development for molecular imaging of bacterial infections

    Article • Clinical and Translational Imaging, February 2019, Springer Science + Business Media

    Dr. Mick Welling

  27. In vivo stability of supramolecular host–guest complexes monitored by dual-isotope multiplexing in a pre-targeting model of experimental liver radioembolization

    Article • Journal of Controlled Release, January 2019, Elsevier

    Dr. Mick Welling

  28. Structure-Activity Relationship Study of Synthetic Variants Derived from the Highly Potent Human Antimicrobial Peptide hLF(1-11)

    Article • Cohesive Journal of Microbiology & Infectious Disease, March 2018, Crimson Publishers

    Dr. Mick Welling

  29. Tracers for Fluorescence-Guided Surgery: How Elongation of the Polymethine Chain in Cyanine Dyes Alters the Pharmacokinetics of a Dual-Modality c[RGDyK] Tracer

    Article • Journal of Nuclear Medicine, February 2018, Society of Nuclear Medicine

    Dr. Mick Welling

  30. A Supramolecular Approach for Liver Radioembolization

    Article • Theranostics, January 2018, Ivyspring International Publisher

    Dr. Mick Welling

  31. Obtaining control of cell surface functionalizations via Pre-targeting and Supramolecular host guest interactions

    Article • Scientific Reports, January 2017, Springer Science + Business Media

    Dr. Mick Welling

  32. Bis-pyridylethenyl benzene as novel backbone for amyloid-β binding compounds

    Article • Bioorganic & Medicinal Chemistry, December 2016, Elsevier

    Dr. Mick Welling

  33. Tailoring Fluorescent Dyes To Optimize a Hybrid RGD-Tracer

    Article • Bioconjugate Chemistry, April 2016, American Chemical Society (ACS)

    Dr. Mick Welling

  34. Fusion of hIgG1-Fc to 111In-anti-amyloid single domain antibody fragment VHH-pa2H prolongs blood residential time in APP/PS1 mice but does not increase brain uptake

    Article • Nuclear Medicine and Biology, August 2015, Elsevier

    Dr. Mick Welling

  35. Erratum to: First-in-human evaluation of a hybrid modality that allows combined radio- and (near-infrared) fluorescence tracing during surgery

    Article • European Journal of Pediatrics, July 2015, Springer Science + Business Media

    Dr. Mick Welling

  36. First-in-human evaluation of a hybrid modality that allows combined radio- and (near-infrared) fluorescence tracing during surgery

    Article • European Journal of Pediatrics, June 2015, Springer Science + Business Media

    Dr. Mick Welling

  37. Development of a Hybrid Tracer for SPECT and Optical Imaging of Bacterial Infections

    Article • Bioconjugate Chemistry, April 2015, American Chemical Society (ACS)

    Dr. Mick Welling

  38. Enhanced glutathione PEGylated liposomal brain delivery of an anti-amyloid single domain antibody fragment in a mouse model for Alzheimer's disease

    Article • Journal of Controlled Release, April 2015, Elsevier

    Dr. Mick Welling

  39. Potential role of antimicrobial peptides in the early onset of Alzheimer's disease

    Article • Alzheimer s & Dementia, January 2015, Elsevier

    Dr. Mick Welling

  40. Polyfluorinated bis-styrylbenzenes as amyloid-β plaque binding ligands

    Article • Bioorganic & Medicinal Chemistry, April 2014, Elsevier

    Dr. Mick Welling

  41. Development and Prospects of Dedicated Tracers for the Molecular Imaging of Bacterial Infections

    Article • Bioconjugate Chemistry, November 2013, American Chemical Society (ACS)

    Dr. Mick Welling

  42. Optical imaging as an expansion of nuclear medicine: Cerenkov-based luminescence vs fluorescence-based luminescence

    Article • European Journal of Pediatrics, May 2013, Springer Science + Business Media

    Dr. Mick Welling

  43. In Vivo Detection of Amyloid-β Deposits Using Heavy Chain Antibody Fragments in a Transgenic Mouse Model for Alzheimer's Disease

    Article • PLOS One, June 2012, PLOS

    Dr. Mick Welling

  44. Prosthetic joint infections: radionuclide state-of-the-art imaging

    Article • European Journal of Pediatrics, February 2012, Springer Science + Business Media

    Dr. Mick Welling

  45. Pretreatment with Interferon-γ Enhances the Therapeutic Activity of Mesenchymal Stromal Cells in Animal Models of Colitis

    Article • Stem Cells, September 2011, Wiley

    Dr. Mick Welling

  46. Discovery and development of a synthetic peptide derived from lactoferrin for clinical use

    Article • Peptides, September 2011, Elsevier

    Dr. Mick Welling

  47. In vivo biodistribution of stem cells using molecular nuclear medicine imaging

    Article • Journal of Cellular Physiology, March 2011, Wiley

    Dr. Mick Welling, Alberto Signore

  48. Performance of a 99mTc-labelled 1-thio-β-D-glucose 2,3,4,6-tetra-acetate analogue in the detection of infections and tumours in mice: a comparison with [18F]FDG

    Article • Nuclear Medicine Communications, March 2010, Wolters Kluwer Health

    Dr. Mick Welling

  49. Current Status of Imaging Infections with Radiolabeled Anti-Infective Agents

    Article • Anti-Infective Agents in Medicinal Chemistry, July 2009, Bentham Science Publishers

    Dr. Mick Welling

  50. Future Diagnostic Agents

    Article • Seminars in Nuclear Medicine, January 2009, Elsevier

    Dr. Mick Welling

  51. The Use of Technetium-99m Radiolabeled Human Antimicrobial Peptides for Infection Specific Imaging

    Article • Mini-Reviews in Medicinal Chemistry, September 2008, Bentham Science Publishers

    Dr. Mick Welling

  52. Various routes of administration of 99mTc-labeled synthetic lactoferrin antimicrobial peptide hLF 1–11 enables monitoring and effective killing of multidrug-resistant Staphylococcus aureus infections in mice

    Article • Peptides, July 2008, Elsevier

    Dr. Mick Welling

  53. The Pharmacology of Radiolabeled Cationic Antimicrobial Peptides

    Article • Journal of Pharmaceutical Sciences, May 2008, Elsevier

    Dr. Mick Welling

  54. The many roads to infection imaging

    Article • European Journal of Pediatrics, January 2008, Springer Science + Business Media

    Dr. Mick Welling

  55. Human Lactoferrin‐Derived Peptide's Antifungal Activities against DisseminatedCandida albicansInfection

    Article • The Journal of Infectious Diseases, November 2007, Oxford University Press (OUP)

    Dr. Mick Welling

  56. The many roads to infection imaging

    Article • European Journal of Pediatrics, September 2007, Springer Science + Business Media

    Dr. Mick Welling

  57. Histatin-Derived Monomeric and Dimeric Synthetic Peptides Show Strong Bactericidal Activity towards Multidrug-Resistant Staphylococcus aureus In Vivo

    Article • Antimicrobial Agents and Chemotherapy, July 2007, ASM Journals

    Dr. Mick Welling

  58. Functional imaging of multidrug resistance in an orthotopic model of osteosarcoma using 99mTc-sestamibi

    Article • European Journal of Pediatrics, June 2007, Springer Science + Business Media

    Dr. Mick Welling, Professor Pancras C.W. Hogendoorn

  59. Evaluation of 99mTc-UBI 29-41 scintigraphy for specific detection of experimental Staphylococcus aureus prosthetic joint infections

    Article • European Journal of Pediatrics, March 2007, Springer Science + Business Media

    Dr. Mick Welling

  60. Dendritic cells, but not macrophages or B cells, activate major histocompatibility complex class II-restricted CD4+T cells upon immune-complex uptake in vivo

    Article • Immunology, December 2006, Wiley

    Dr. Mick Welling

  61. Synthetic peptides derived from human antimicrobial peptide ubiquicidin accumulate at sites of infections and eradicate (multi-drug resistant) Staphylococcus aureus in mice

    Article • Peptides, November 2006, Elsevier

    Dr. Mick Welling

  62. Multidrug resistance mediated by ABC transporters in osteosarcoma cell lines: mRNA analysis and functional radiotracer studies

    Article • Nuclear Medicine and Biology, October 2006, Elsevier

    Dr. Mick Welling, Professor Pancras C.W. Hogendoorn

  63. Radionuclide imaging of spinal infections

    Article • European Journal of Pediatrics, July 2006, Springer Science + Business Media

    Dr. Mick Welling

  64. Ex vivo culture of human CD34+ cord blood cells with thrombopoietin (TPO) accelerates platelet engraftment in a NOD/SCID mouse model

    Article • Experimental Hematology, July 2006, Elsevier

    Dr. Mick Welling

  65. Detection of Fungal Infections Using Radiolabeled Antifungal Agents

    Article • Current Drug Targets, December 2005, Bentham Science Publishers

    Dr. Mick Welling

  66. Outcome of intensive immunosuppression and autologous stem cell transplantation in patients with severe rheumatoid arthritis is associated with the composition of synovial T cell infiltration

    Article • Annals of the Rheumatic Diseases, October 2005, BMJ

    Dr. Mick Welling

  67. Kit with technetium-99m labelled antimicrobial peptide UBI 29-41 for specific infection detection

    Article • Journal of Labelled Compounds, January 2005, Wiley

    Dr. Mick Welling

  68. New chelation strategy allows for quick and clean 99mTc-labeling of synthetic peptides

    Article • Nuclear Medicine and Biology, August 2004, Elsevier

    Dr. Mick Welling

  69. Infection detection in mice using 99mTc-labeled HYNIC and N2S2 chelate conjugated to the antimicrobial peptide UBI 29-41

    Article • Nuclear Medicine and Biology, May 2004, Elsevier

    Dr. Mick Welling

  70. Radiolabelled antimicrobial peptides for infection detection

    Article • The Lancet Infectious Diseases, April 2003, Elsevier

    Dr. Mick Welling

  71. Radiopharmaceuticals: new antimicrobial agents

    Article • Trends in Biotechnology, February 2003, Elsevier

    Dr. Mick Welling

  72. Synergistic Activity of the N-Terminal Peptide of Human Lactoferrin and Fluconazole against Candida Species

    Article • Antimicrobial Agents and Chemotherapy, January 2003, ASM Journals

    Dr. Mick Welling

  73. Technetium-99m labeled cationic antimicrobial peptides for infection detection and treatment monitoring

    Article • Drugs of the Future, January 2003, Thomson Reuters (Scientific) Inc. & Affiliates

    Dr. Mick Welling

  74. Large scale production of recombinant human lactoferrin in the milk of transgenic cows

    Article • Nature Biotechnology, May 2002, Springer Science + Business Media

    Dr. Mick Welling

  75. Radiochemical and biological characteristics of 99mTc-UBI 29–41 for imaging of bacterial infections

    Article • Nuclear Medicine and Biology, May 2002, Elsevier

    Dr. Mick Welling

  76. Technetium-99m labelled fluconazole and antimicrobial peptides for imaging of Candida albicans and Aspergillus fumigatus infections

    Article • European Journal of Pediatrics, March 2002, Springer Science + Business Media

    Dr. Mick Welling

  77. Improved radioiodination of biomolecules using exhaustive Chloramine-T oxidation

    Article • Nuclear Medicine and Biology, November 2001, Elsevier

    Dr. Mick Welling

  78. Concerns about 99mTc-labelled ciprofloxacin for infection detection

    Article • European Journal of Pediatrics, June 2001, Springer Science + Business Media

    Dr David W Wareham, Dr. Mick Welling

  79. Reply

    Article • European Journal of Pediatrics, June 2001, Springer Science + Business Media

    Dr. Mick Welling

  80. Human Lactoferrin and Peptides Derived from Its N Terminus Are Highly Effective against Infections with Antibiotic-Resistant Bacteria

    Article • Infection and Immunity, March 2001, ASM Journals

    Dr. Mick Welling

  81. Candidacidal Activities of Human Lactoferrin Peptides Derived from the N Terminus

    Article • Antimicrobial Agents and Chemotherapy, December 2000, ASM Journals

    Dr. Mick Welling

  82. Concerns about 99mTc-labelled ciprofloxacin for infection detection

    Article • European Journal of Pediatrics, October 2000, Springer Science + Business Media

    Dr. Mick Welling

  83. Technetium-99m labelled antimicrobial peptides discriminate between bacterial infections and sterile inflammations

    Article • European Journal of Pediatrics, October 2000, Springer Science + Business Media

    Dr. Mick Welling

  84. Technetium-99m labelled antimicrobial peptides discriminate between bacterial infections and sterile inflammations

    Article • European Journal of Pediatrics, March 2000, Springer Science + Business Media

    Dr. Mick Welling

  85. Interaction of a monoclonal antibody against hEGF with a receptor site for EGF

    Article • Nuclear Medicine and Biology, November 1999, Elsevier

    Dr. Mick Welling

  86. Radiolabelled antimicrobial peptides for imaging of infections

    Article • Nuclear Medicine Communications, December 1998, Wolters Kluwer Health

    Dr. Mick Welling

  87. Antibacterial activity of human neutrophil defensins in experimental infections in mice is accompanied by increased leukocyte accumulation.

    Article • Journal of Clinical Investigation, October 1998, American Society for Clinical Investigation

    Dr. Mick Welling

  88. Localization of a bacterial infection with 99Tcm-labelled human IgG

    Article • Nuclear Medicine Communications, November 1997, Wolters Kluwer Health

    Dr. Mick Welling

  89. Detection of experimental infections with 99mTc-labeled monoclonal antibodies against TNF-α and interleukin-8

    Article • Nuclear Medicine and Biology, October 1997, Elsevier

    Dr. Mick Welling

  90. 99Tcm-HIG accumulates in the synovial tissue of rats with adjuvant arthritis by binding to extracellular matrix proteins

    Article • Nuclear Medicine Communications, January 1996, Wolters Kluwer Health

    Dr. Mick Welling

  91. Contribution of phagocytic cells and bacteria to the accumulation of technetium-99m labelled polyclonal human immunoglobulin at sites of inflammation

    Article • European Journal of Pediatrics, July 1995, Springer Science + Business Media

    Dr. Mick Welling

  92. Optimized localization of bacterial infections with technetium-99m labelled human immunoglobulin after protein charge selection

    Article • European Journal of Pediatrics, October 1994, Springer Science + Business Media

    Dr. Mick Welling

  93. The labeling of proteins and LDL with 99mTc: a new direct method employing KBH4 and stannous chloride

    Article • Nuclear Medicine and Biology, October 1993, Elsevier

    Dr. Mick Welling

  94. Improved detection of a staphylococcal infection by monomeric and protein A-purified polyclonal human immunoglobulin

    Article • European Journal of Pediatrics, June 1993, Springer Science + Business Media

    Dr. Mick Welling

  95. Effects of an Antifibrin Monoclonal Antibody and Fragments thereof on Some Properties of Fibrin

    Article • Thrombosis and Haemostasis, January 1990, Thieme Publishing Group

    Dr. Mick Welling