All Stories

  1. The Impact of Moderate Chronic Hypoxia and Hyperoxia on the Level of Apoptotic and Autophagic Proteins in Myocardial Tissue

    Article • Oxidative Medicine and Cellular Longevity, August 2018, Hindawi Publishing Corporation

    Professor Michele Samaja

  2. Sildenafil attenuates hypoxic pulmonary remodelling by inhibiting bone marrow progenitor cells

    Article • Journal of Cellular and Molecular Medicine, November 2016, Wiley

    Professor Michele Samaja

  3. Editorial – Hypoxia and Reoxygenation: From Basic Science to Bedside

    Article • Frontiers in Pediatrics, October 2015, Frontiers

    Professor Michele Samaja

  4. Effects of apelin on the cardiovascular system

    Article • Heart Failure Reviews, February 2015, Springer Science + Business Media

    Professor Michele Samaja

  5. Erythropoietin's inhibiting impact on hepcidin expression occurs indirectly

    Article • AJP Regulatory Integrative and Comparative Physiology, December 2014, American Physiological Society

    Professor Michele Samaja

  6. In vivo hyperoxia induces hypoxia-inducible factor-1α overexpression in LNCaP tumors without affecting the tumor growth rate

    Article • The International Journal of Biochemistry & Cell Biology, June 2014, Elsevier

    Professor Michele Samaja

  7. Antitumour activity of melatonin in a mouse model of human prostate cancer: relationship with hypoxia signalling

    Article • Journal of Pineal Research, May 2014, Wiley

    Professor Michele Samaja

  8. Impact of acellular hemoglobin-based oxygen carriers on brain apoptosis in rats

    Article • Transfusion, March 2014, Wiley

    Professor Michele Samaja

  9. Expression of carbohydrate-antigen sialyl-Lewis a on colon cancer cells promotes xenograft growth and angiogenesis in nude mice

    Article • The International Journal of Biochemistry & Cell Biology, December 2013, Elsevier

    Professor Michele Samaja

  10. Supplementation of Creatine and Ribose Prevents Apoptosis and Right Ventricle Hypertrophy in Hypoxic Hearts

    Article • Current Pharmaceutical Design, November 2013, Bentham Science Publishers

    Professor Michele Samaja

  11. Impact of the Phosphatidylinositide 3-Kinase Signaling Pathway on the Cardioprotection Induced by Intermittent Hypoxia

    Article • PLoS ONE, October 2013, PLOS

    Professor Michele Samaja

  12. Autophagy and Human Parturition: Evaluation of LC3 Expression in Placenta from Spontaneous or Medically Induced Onset of Labor

    Article • BioMed Research International, January 2013, Hindawi Publishing Corporation

    Professor Michele Samaja

  13. In vivo up-regulation of the unfolded protein response after hypoxia

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, July 2012, Elsevier

    Professor Michele Samaja

  14. Correction: Phosphodiesterase-5 Inhibition Mimics Intermittent Reoxygenation and Improves Cardioprotection in the Hypoxic Myocardium

    Article • PLoS ONE, January 2012, PLOS

    Professor Michele Samaja

  15. Habituation

    Article • January 2012, Springer Science + Business Media

    Professor Michele Samaja

  16. Phosphodiesterase-5 Inhibition Mimics Intermittent Reoxygenation and Improves Cardioprotection in the Hypoxic Myocardium

    Article • PLoS ONE, November 2011, PLOS

    Professor Michele Samaja

  17. Protein modulation in mouse heart under acute and chronic hypoxia

    Article • PROTEOMICS, September 2011, Wiley

    Professor Michele Samaja

  18. Impact of Hemoglobin Concentration and Affinity for Oxygen on Tissue Oxygenation: The Case of Hemoglobin-Based Oxygen Carriers

    Article • Artificial Organs, August 2011, Wiley

    Professor Michele Samaja

  19. Myocardial tolerance to ischemia–reperfusion injury, training intensity and cessation

    Article • European Journal of Applied Physiology and Occupational Physiology, November 2010, Springer Science + Business Media

    Professor Michele Samaja

  20. Daily reoxygenation decreases myocardial injury and improves post-ischaemic recovery after chronic hypoxia☆

    Article • European Journal of Cardio-Thoracic Surgery, April 2010, Oxford University Press (OUP)

    Professor Michele Samaja

  21. Chronic systemic hypoxia promotes LNCaP prostate cancer growth in vivo

    Article • The Prostate, March 2010, Wiley

    Professor Michele Samaja

  22. Supplementation of Creatine and Ribose Prevents Apoptosis in Ischemic Cardiomyocytes

    Article • Cellular Physiology and Biochemistry, January 2010, Karger Publishers

    Professor Michele Samaja

  23. Gene expression profile of rat left ventricles reveals persisting changes following chronic mild exercise protocol: implications for cardioprotection

    Article • BMC Genomics, January 2009, Springer Science + Business Media

    Professor Michele Samaja

  24. Modulation of the NO/cGMP pathway reduces the vasoconstriction induced by acellular and PEGylated haemoglobin

    Article • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, October 2008, Elsevier

    Professor Michele Samaja

  25. Cellular distribution of Hsp70 expression in rat skeletal muscles. Effects of moderate exercise training and chronic hypoxia

    Article • Cell Stress and Chaperones, June 2008, Springer Science + Business Media

    Professor Michele Samaja

  26. Partial persistence of exercise-induced myocardial angiogenesis following 4-week detraining in the rat

    Article • Histochemistry and Cell Biology, January 2008, Springer Science + Business Media

    Professor Michele Samaja

  27. Long-Term Use of Sildenafil in the Therapeutic Management of Heart Failure

    Article • Journal of the American College of Cardiology, November 2007, Elsevier

    Professor Michele Samaja

  28. The Role of PDE5-Inhibitors in Cardiopulmonary Disorders: From Basic Evidence to Clinical Development

    Article • Current Medicinal Chemistry, August 2007, Bentham Science Publishers

    Professor Michele Samaja

  29. Mild exercise training, cardioprotection and stress genes profile

    Article • European Journal of Applied Physiology and Occupational Physiology, January 2007, Springer Science + Business Media

    Professor Michele Samaja

  30. Oxidation and haem loss kinetics of poly(ethylene glycol)-conjugated haemoglobin (MP4): dissociation between in vitro and in vivo oxidation rates

    Article • Biochemical Journal, November 2006, Portland Press Ltd.

    Professor Michele Samaja

  31. Cytochromec oxidase expression in chronic and intermittent hypoxia rat gastrocnemius muscle quantitated by CE

    Article • Electrophoresis, October 2006, Wiley

    Professor Michele Samaja

  32. Brief reoxygenation episodes during chronic hypoxia enhance posthypoxic recovery of LV function

    Article • Basic Research in Cardiology, May 2006, Springer Science + Business Media

    Professor Michele Samaja

  33. Chronic in vivo hypoxia in various organs: Hypoxia-inducible factor-1α and apoptosis

    Article • Biochemical and Biophysical Research Communications, April 2006, Elsevier

    Professor Michele Samaja

  34. Effects of broad band electromagnetic fields on HSP70 expression and ischemia-reperfusion in rat hearts

    Article • Life Sciences, September 2004, Elsevier

    Professor Michele Samaja

  35. Kinetics of NO and O 2 binding to a maleimide poly(ethylene glycol)-conjugated human haemoglobin

    Article • Biochemical Journal, August 2004, Portland Press Ltd.

    Professor Andrea Bellelli, Professor Michele Samaja

  36. Hypoxia: Unique myocardial morphology?

    Article • Journal of Thoracic and Cardiovascular Surgery, May 2004, Elsevier

    Professor Michele Samaja

  37. Xanthine Oxido-reductase Activity in Ischemic Human and Rat Intestine

    Article • Free Radical Research, January 2004, Taylor & Francis

    Professor Michele Samaja

  38. Acid?base balance at exercise in normoxia and in chronic hypoxia. Revisiting the "lactate paradox"

    Article • European Journal of Applied Physiology and Occupational Physiology, November 2003, Springer Science + Business Media

    Professor Michele Samaja

  39. Oxygen transport in blood at high altitude: role of the hemoglobin?oxygen affinity and impact of the phenomena related to hemoglobin allosterism and red cell function

    Article • European Journal of Applied Physiology and Occupational Physiology, October 2003, Springer Science + Business Media

    Professor Michele Samaja

  40. Effect of contraction frequency on the contractile and noncontractile phases of muscle venous blood flow

    Article • Journal of Applied Physiology, June 2003, American Physiological Society

    Professor Michele Samaja

  41. Simultaneous determination of purine nucleotides, their metabolites and β-nicotinamide adenine dinucleotide in cerebellar granule cells by ion-pair high performance liquid chromatography

    Article • Brain Research Protocols, February 2003, Elsevier

    Professor Michele Samaja

  42. Chronic hypoxia: A model for cyanotic congenital heart defects

    Article • Journal of Thoracic and Cardiovascular Surgery, July 2002, Elsevier

    Professor Michele Samaja

  43. Amino acid- and lipid-induced insulin resistance in rat heart: molecular mechanisms

    Article • Molecular and Cellular Endocrinology, April 2002, Elsevier

    Professor Michele Samaja

  44. Low-flow Ischemia and Hypoxia Stimulate Apoptosis in Perfused Hearts Independently of Reperfusion

    Article • Cellular Physiology and Biochemistry, January 2002, Karger Publishers

    Professor Michele Samaja

  45. Hypoxia-dependent Protein Expression: Erythropoietin

    Article • High Altitude Medicine & Biology, June 2001, Mary Ann Liebert Inc

    Professor Michele Samaja

  46. Detection of Haemoglobins with Abnormal Oxygen Affinity by Single Blood Gas Analysis and 2,3-Diphosphoglycerate Measurement

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), January 2000, De Gruyter

    Professor Michele Samaja

  47. ATENOLOL DEPRESSES POST-ISCHAEMIC RECOVERY IN THE ISOLATED RAT HEART

    Article • Pharmacological Research, June 1999, Elsevier

    Professor Michele Samaja

  48. Blood Gas Transport at High Altitude

    Article • Respiration, January 1997, Karger Publishers

    Professor Michele Samaja

  49. Myocardial Adaptation to Acute Oxygen Shortage

    Article • January 1997, Springer Science + Business Media

    Professor Michele Samaja

  50. The effects of the rate of reoxygenation on the recovery of hypoxemic hearts

    Article • Journal of Thoracic and Cardiovascular Surgery, June 1995, Elsevier

    Professor Michele Samaja

  51. [39] Oxidation of olefins catalyzed by hemoglobin

    Article • January 1994, Elsevier

    Professor Michele Samaja

  52. Effects of Energy Demand in Ischemic and in Hypoxemic Isolated Rat Hearts

    Article • January 1994, Springer Science + Business Media

    Professor Michele Samaja

  53. Recovery of hypoxic neonatal hearts after cardioplegic arrest

    Article • Cardiovascular Research, November 1993, European Society of Cardiology

    Professor Michele Samaja

  54. Thyroid hormones and active calcium transport of inside-out red cell membrane vesicles

    Article • Biochemical Medicine and Metabolic Biology, December 1992, Elsevier

    Professor Michele Samaja

  55. Functional and metabolic effects of propionyl-L-carnitine in the isolated perfused hypertrophied rat heart

    Article • Molecular and Cellular Biochemistry, October 1992, Springer Science + Business Media

    Professor Michele Samaja

  56. Functional and metabolic effects of propionyl-L-carnitine in the isolated perfused hypertrophied rat heart

    Article • January 1992, Springer Science + Business Media

    Professor Michele Samaja

  57. Hypoxanthine in stored blood

    Article • Transfusion, May 1991, Wiley

    Professor Michele Samaja

  58. The Relationship Between the Blood Oxygen Transport and the Human Red Cell Aging Process

    Article • January 1991, Springer Science + Business Media

    Professor Michele Samaja

  59. Red cell aging and active calcium transport

    Article • Experimental Gerontology, January 1990, Elsevier

    Professor Michele Samaja

  60. Human red cell age, oxygen affinity and oxygen transport

    Article • Respiration Physiology, January 1990, Elsevier

    Professor Michele Samaja

  61. Prediction of the oxygenation of human organs at varying blood oxygen carrying properties

    Article • Respiration Physiology, May 1988, Elsevier

    Professor Michele Samaja

  62. The dissociation of carbon monoxide from the alpha and the beta subunits of human carbonmonoxy hemoglobin

    Article • Biochemical and Biophysical Research Communications, November 1987, Elsevier

    Professor Michele Samaja

  63. Separation of the valence intermediates of human haemoglobin by high-performance chromatofocusing

    Article • Journal of Chromatography A, June 1987, Elsevier

    Professor Michele Samaja

  64. Purification of human hemoglobin valence intermediates by preparative immobilized pH gradients

    Article • Journal of Biochemical and Biophysical Methods, June 1987, Elsevier

    Professor Michele Samaja

  65. The role of 2,3-DPG in the oxygen transport at altitude

    Article • Respiration Physiology, May 1986, Elsevier

    Professor Michele Samaja

  66. Computerized scheme for the reaction of hemoglobin with ligands

    Article • Journal of Protein Chemistry, October 1985, Springer Science + Business Media

    Professor Michele Samaja

  67. Simulation of oxygen delivery to tissues: The role of the hemoglobin oxygen equilibrium curve at altitude

    Article • International journal of clinical monitoring and computing, June 1985, Springer Science + Business Media

    Professor Michele Samaja

  68. Blood oxygen affinity in large white pig

    Article • Cellular and Molecular Life Sciences, December 1983, Springer Science + Business Media

    Professor Michele Samaja

  69. A new method to measure the haemoglobin oxygen saturation by the oxygen electrode

    Article • Journal of Biochemical and Biophysical Methods, February 1983, Elsevier

    Professor Michele Samaja

  70. Glycosylated haemoglobins and the oxygen affinity of whole blood

    Article • Diabetologia, November 1982, Springer Science + Business Media

    Professor Michele Samaja

  71. Improvement of glycosylated hemoglobin measurement by disposable ion-exchange columns

    Article • La Ricerca in Clinica e in Laboratorio, January 1980, Springer Science + Business Media

    Professor Michele Samaja

  72. A new spectrophotometric cuvette holder for low temperature studies; Its application to the study of carbonmonoxyhemoglobin oxidation rate

    Article • Journal of Biochemical and Biophysical Methods, December 1979, Elsevier

    Professor Michele Samaja

  73. Oxygen affinity in the blood of sheep

    Article • Respiration Physiology, September 1978, Elsevier

    Professor Michele Samaja