All Stories

  1. Toxicity of Flame Retardant Isopropylated Triphenyl Phosphate: Liver, Adrenal, and Metabolic Effects

    Article • International Journal of Toxicology, May 2019, SAGE Publications

    Dr Michael G Wade

  2. A Mixture Reflecting Polybrominated Diphenyl Ether (PBDE) Profiles Detected in Human Follicular Fluid Significantly Affects Steroidogenesis and Induces Oxidative Stress in a Female Human Granulosa Cell Line

    Article • Endocrinology, July 2016, Endocrine Society

    Dr Michael G Wade

  3. Gestational and Early Postnatal Exposure to an Environmentally Relevant Mixture of Brominated Flame Retardants: General Toxicity and Skeletal Variations

    Article • Birth Defects Research Part B Developmental and Reproductive Toxicology, June 2016, Wiley

    Dr Michael G Wade

  4. Hepatic miRNA profiles and thyroid hormone homeostasis in rats exposed to dietary potassium perfluorooctanesulfonate (PFOS)

    Article • Environmental Toxicology and Pharmacology, January 2016, Elsevier

    Dr Michael G Wade

  5. Exposure of Female Rats to an Environmentally Relevant Mixture of Brominated Flame Retardants Targets the Ovary, Affecting Folliculogenesis and Steroidogenesis

    Article • Biology of Reproduction, November 2015, Society for the Study of Reproduction

    Dr Michael G Wade

  6. Toxicogenomic assessment of liver responses following subchronic exposure to furan in Fischer F344 rats

    Article • Archives of Toxicology, July 2015, Springer Science + Business Media

    Dr Michael G Wade

  7. Hair as a Biomarker of Systemic Exposure to Polybrominated Diphenyl Ethers

    Article • Environmental Science & Technology, December 2014, American Chemical Society (ACS)

    Dr Michael G Wade

  8. Correction: Thyroid Hormone Response Element Half-Site Organization and Its Effect on Thyroid Hormone Mediated Transcription

    Article • PLoS ONE, September 2014, PLOS

    Dr Michael G Wade

  9. Thyroid Hormone Response Element Half-Site Organization and Its Effect on Thyroid Hormone Mediated Transcription

    Article • PLoS ONE, June 2014, PLOS

    Dr Michael G Wade

  10. Exposure to an environmentally relevant mixture of brominated flame retardants affects fetal development in Sprague-Dawley rats

    Article • Toxicology, June 2014, Elsevier

    Dr Michael G Wade

  11. Induction of Adipocyte Differentiation by Polybrominated Diphenyl Ethers (PBDEs) in 3T3-L1 Cells

    Article • PLoS ONE, April 2014, PLOS

    Dr Michael G Wade

  12. Transient Maternal Hypothyroxinemia Potentiates the Transcriptional Response to Exogenous Thyroid Hormone in the Fetal Cerebral Cortex Before the Onset of Fetal Thyroid Function: A Messenger and MicroRNA Profiling Study

    Article • Cerebral Cortex, January 2014, Oxford University Press (OUP)

    Dr Michael G Wade

  13. EN

    Article • ALTEX, January 2014, ALTEX Edition

    Dr Michael G Wade

  14. The development of adverse outcome pathways for mutagenic effects for the organization for economic co-operation and development

    Article • Environmental and Molecular Mutagenesis, January 2013, Wiley

    Dr Francesco Marchetti, Dr Michael G Wade

  15. Identification of thyroid hormone receptor binding sites in developing mouse cerebellum

    Article • BMC Genomics, January 2013, Springer Science + Business Media

    Dr Michael G Wade

  16. Loss-of-function mutations in IGSF1 cause an X-linked syndrome of central hypothyroidism and testicular enlargement

    Article • Nature Genetics, November 2012, Nature

    Dr Michael G Wade

  17. Investigating the effects of dietary folic acid on sperm count, DNA damage and mutation in Balb/c mice

    Article • Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, September 2012, Elsevier

    Dr Michael G Wade

  18. Exposure of pregnant mice to carbon black by intratracheal instillation: Toxicogenomic effects in dams and offspring

    Article • Mutation Research/Genetic Toxicology and Environmental Mutagenesis, June 2012, Elsevier

    Professor Ulla B Vogel, Dr Michael G Wade

  19. Effects of Chronic Exposure to an Environmentally Relevant Mixture of Brominated Flame Retardants on the Reproductive and Thyroid System in Adult Male Rats

    Article • Toxicological Sciences, March 2012, Oxford University Press (OUP)

    Dr Michael G Wade

  20. Barhl1 is directly regulated by thyroid hormone in the developing cerebellum of mice

    Article • Biochemical and Biophysical Research Communications, November 2011, Elsevier

    Dr Michael G Wade

  21. Interlaboratory study comparison of the 15-day intact adult male rat screening assay: evaluation of an antithyroid chemical and a negative control chemical

    Article • Birth Defects Research Part B Developmental and Reproductive Toxicology, January 2011, Wiley

    Dr Michael G Wade

  22. Thyroid hormone-regulated gene expression in juvenile mouse liver: identification of thyroid response elements using microarray profiling and in silico analyses

    Article • BMC Genomics, January 2011, Springer Science + Business Media

    Dr Michael G Wade

  23. Thyroid Hormone May Regulate mRNA Abundance in Liver by Acting on MicroRNAs

    Article • PLoS ONE, August 2010, PLOS

    Dr Michael G Wade

  24. Low Levels of the Herbicide Atrazine Alter Sex Ratios and Reduce Metamorphic Success in Rana pipiens Tadpoles Raised in Outdoor Mesocosms

    Article • Environmental Health Perspectives, November 2009, Environmental Health Perspectives

    Dr Michael G Wade

  25. Assessment of thyroid system disruption in Rana pipiens tadpoles chronically exposed to UVB radiation and 4-tert-octylphenol

    Article • Aquatic Toxicology, November 2009, Elsevier

    Dr Michael G Wade

  26. Identification of Thyroid Hormone Receptor Binding Sites and Target Genes Using ChIP-on-Chip in Developing Mouse Cerebellum

    Article • PLoS ONE, February 2009, PLOS

    Dr Michael G Wade

  27. The Aromatase Inhibitor Fadrozole and the 5-Reductase Inhibitor Finasteride Affect Gonadal Differentiation and Gene Expression in the FrogSilurana tropicalis

    Article • Sexual Development, January 2009, Karger Publishers

    Dr Michael G Wade

  28. Toxicological Effects of In Utero and Lactational Exposure of Rats to a Mixture of Environmental Contaminants Detected in Canadian Arctic Human Populations

    Article • Journal of Toxicology and Environmental Health Part A, December 2008, Taylor & Francis

    Dr Michael G Wade

  29. Methoxyacetic Acid-Induced Spermatocyte Death Is Associated with Histone Hyperacetylation in Rats1

    Article • Biology of Reproduction, May 2008, Oxford University Press (OUP)

    Dr Michael G Wade

  30. Estrogenic exposure affects metamorphosis and alters sex ratios in the northern leopard frog (Rana pipiens): Identifying critically vulnerable periods of development

    Article • General and Comparative Endocrinology, May 2008, Elsevier

    Dr Michael G Wade

  31. Meeting Report: Measuring Endocrine-Sensitive Endpoints within the First Years of Life

    Article • Environmental Health Perspectives, April 2008, Environmental Health Perspectives

    Dr Michael G Wade

  32. Testicular Cancer and Hormonally Active Agents∗

    Article • Journal of Toxicology and Environmental Health Part B, March 2008, Taylor & Francis

    Dr Michael G Wade

  33. Proteomic investigation of 1,6-dimethoxyhexane testicular toxicity

    Article • Environmental Toxicology and Pharmacology, September 2007, Elsevier

    Dr Michael G Wade

  34. Hepatic Gene Expression Changes in Hypothyroid Juvenile Mice: Characterization of a Novel Negative Thyroid-Responsive Element

    Article • Endocrinology, August 2007, Endocrine Society

    Dr Michael G Wade

  35. Environmental Hazards: Evidence for Effects on Child Health

    Article • Journal of Toxicology and Environmental Health Part B, January 2007, Taylor & Francis

    Dr Michael G Wade

  36. Flow cytometric detection of tandem repeat mutations induced by various chemical classes

    Article • Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, June 2006, Elsevier

    Dr Michael G Wade

  37. Toxicological Effects of Gestational and Lactational Exposure to a Mixture of Persistent Organochlorines in Rats: Systemic Effects

    Article • Toxicological Sciences, December 2005, Oxford University Press (OUP)

    Dr Michael G Wade

  38. Testicular Toxicity of Candidate Fuel Additive 1,6-Dimethoxyhexane: Comparison with Several Similar Aliphatic Ethers

    Article • Toxicological Sciences, October 2005, Oxford University Press (OUP)

    Dr Michael G Wade

  39. Changes in spermatozoal chromatin packaging and susceptibility to oxidative challenge during aging

    Article • Fertility and Sterility, October 2005, Elsevier

    Dr Michael G Wade

  40. Short-term oral toxicity of butyl ether, ethyl hexyl ether, methyl heptyl ether and 1,6-dimethoxyhexane in male rats and the role of 2-methoxyacetic acid

    Article • Toxicology, October 2005, Elsevier

    Dr Michael G Wade

  41. Molecular insight into the effects of hypothyroidism on the developing cerebellum

    Article • Biochemical and Biophysical Research Communications, May 2005, Elsevier

    Dr Michael G Wade

  42. Effects of Postnatal Exposure to a Mixture of Polychlorinated Biphenyls, p,p′-dichlorodiphenyltrichloroethane, and p-p′-dichlorodiphenyldichloroethene in Prepubertal and Adult Female Sprague-Dawley Rats

    Article • International Journal of Toxicology, March 2005, SAGE Publications

    Dr Michael G Wade

  43. Exposure to Trichloroethylene and its Metabolites Causes Impairment of Sperm Fertilizing Ability in Mice

    Article • Toxicological Sciences, December 2004, Oxford University Press (OUP)

    Dr Michael G Wade

  44. Mammary Gland Morphology in Sprague-Dawley Rats following Treatment with an Organochlorine Mixture in Utero and Neonatal Genistein

    Article • Toxicological Sciences, December 2003, Oxford University Press (OUP)

    Dr Michael G Wade

  45. Early Developmental Neurotoxicity of a PCB/Organochlorine Mixture in Rodents after Gestational and Lactational Exposure

    Article • Toxicological Sciences, December 2003, Oxford University Press (OUP)

    Dr Michael G Wade

  46. The influence of dietary isoflavone on the uterotrophic response in juvenile rats

    Article • Food and Chemical Toxicology, November 2003, Elsevier

    Dr Michael G Wade

  47. Acquisition of Arylsulfatase A onto the Mouse Sperm Surface During Epididymal Transit

    Article • Biology of Reproduction, May 2003, Society for the Study of Reproduction

    Dr Michael G Wade

  48. Letter

    Article • Toxicological Sciences, September 2002, Oxford University Press (OUP)

    Dr Michael G Wade

  49. Thyroid Toxicity Due to Subchronic Exposure to a Complex Mixture of 16 Organochlorines, Lead, and Cadmium

    Article • Toxicological Sciences, June 2002, Oxford University Press (OUP)

    Dr Michael G Wade

  50. Effects of Subchronic Exposure to a Complex Mixture of Persistent Contaminants in Male Rats: Systemic, Immune, and Reproductive Effects

    Article • Toxicological Sciences, May 2002, Oxford University Press (OUP)

    Dr Michael G Wade

  51. Reproductive effects of tris(4-chlorophenyl)methanol in the rat

    Article • Chemosphere, August 1999, Elsevier

    Dr Michael G Wade

  52. Effects of acute exposure to PCBs 126 and 153 on anterior pituitary and thyroid hormones and FSH isoforms in adult Sprague Dawley male rats

    Article • Toxicological Sciences, February 1999, Oxford University Press (OUP)

    Dr Michael G Wade

  53. Interactions between endosulfan and dieldrin on estrogen-mediated processes in vitro and in vivo

    Article • Reproductive Toxicology, January 1997, Elsevier

    Dr Michael G Wade

  54. Influence of the muscarinic agonist carbachol on intracellular Ca2+ in chicken granulosa cells: I. Dependence on follicular maturation

    Article • Biology of Reproduction, April 1995, Society for the Study of Reproduction

    Dr Michael G Wade

  55. Release and steroidogenic actions of polyunsaturated fatty acids in the goldfish testis

    Article • Biology of Reproduction, July 1994, Society for the Study of Reproduction

    Dr Michael G Wade

  56. Polyunsaturated fatty acids do not activate protein kinase C in the testis of the goldfish (Carassius auratus)

    Article • Fish Physiology and Biochemistry, May 1994, Springer Science + Business Media

    Dr Michael G Wade

  57. Arachidonic Acid and Prostaglandin E2 Stimulate Testosterone Production by Goldfish Testis in Vitro

    Article • General and Comparative Endocrinology, April 1993, Elsevier

    Dr Michael G Wade

  58. The control of testicular androgen production in the goldfish: Effects of activators of different intracellular signalling pathways

    Article • General and Comparative Endocrinology, September 1991, Elsevier

    Dr Michael G Wade