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  1. Metformin, Empagliflozin, and Their Combination Modulate Ex-Vivo Macrophage Inflammatory Gene Expression

    Article • International Journal of Molecular Sciences, March 2023, MDPI AG

    Dr Matthew C Gage

  2. Metformin, empagliflozin and their combination modulate ex-vivo macrophage inflammatory gene expression

    Article • June 2022, Cold Spring Harbor Laboratory Press

    Dr Matthew C Gage

  3. The Immunomodulatory Effects of Statins on Macrophages

    Article • Immuno, April 2022, MDPI AG

    Dr Matthew C Gage

  4. Challenges and solutions for diabetes early career researchers in the COVID‐19 recovery: Perspectives of the Diabetes UK Innovators in Diabetes

    Article • Diabetic Medicine, September 2021, Wiley

    Dr Matthew C Gage

  5. Metabolic Hormones Modulate Macrophage Inflammatory Responses

    Article • Cancers, September 2021, MDPI AG

    Dr Matthew C Gage

  6. Liver macrophages and inflammation in physiology and physiopathology of non‐alcoholic fatty liver disease

    Article • European Journal of Biochemistry, May 2021, Wiley

    Dr Matthew C Gage

  7. LXRα Phosphorylation in Cardiometabolic Disease: Insight From Mouse Models

    Article • Endocrinology, June 2020, Endocrine Society

    Dr Matthew C Gage

  8. Impaired LXRα Phosphorylation Attenuates Progression of Fatty Liver Disease

    Article • Cell Reports, January 2019, Elsevier

    Dr Matthew C Gage

  9. Aged insulin resistant macrophages reveal dysregulated cholesterol biosynthesis, a pro-inflammatory profile and reduced foam cell formation capacity

    Article • November 2018, Cold Spring Harbor Laboratory Press

    Dr Matthew C Gage

  10. Disrupting LXRα phosphorylation promotes FoxM1 expression and modulates atherosclerosis by inducing macrophage proliferation

    Article • Proceedings of the National Academy of Sciences, June 2018, Proceedings of the National Academy of Sciences

    Dr Matthew C Gage

  11. Endothelial SHIP2 Suppresses Nox2 NADPH Oxidase–Dependent Vascular Oxidative Stress, Endothelial Dysfunction, and Systemic Insulin Resistance

    Article • Diabetes, August 2017, American Diabetes Association

    Dr Matthew C Gage

  12. Selective Enhancement of Insulin Sensitivity in the Endothelium In Vivo Reveals a Novel Proatherosclerotic Signaling Loop

    Article • Circulation Research, March 2017, Wolters Kluwer Health

    Dr Matthew C Gage

  13. A G1‐like state allows HIV ‐1 to bypass SAMHD 1 restriction in macrophages

    Article • The EMBO Journal, January 2017, EMBO

    Dr Matthew C Gage

  14. Nuclear receptors regulate metabolism

    Article • Endocrinology, December 2016, Endocrine Society

    Dr Matthew C Gage, Natalia Becares

  15. The nuclear receptor LXR modulates interleukin-18 levels in macrophages through multiple mechanisms

    Article • Scientific Reports, May 2016, Springer Science + Business Media

    Dr Matthew C Gage

  16. In Silico Design and Biological Evaluation of a Dual Specificity Kinase Inhibitor Targeting Cell Cycle Progression and Angiogenesis

    Article • PLoS ONE, November 2014, PLOS

    Dr Matthew C Gage

  17. Restoring Akt1 Activity in Outgrowth Endothelial Cells From South Asian Men Rescues Vascular Reparative Potential

    Article • Stem Cells, September 2014, Wiley

    Dr Matthew C Gage

  18. Haploinsufficiency of the Insulin-Like Growth Factor-1 Receptor Enhances Endothelial Repair and Favorably Modifies Angiogenic Progenitor Cell Phenotype

    Article • Arteriosclerosis Thrombosis and Vascular Biology, September 2014, Wolters Kluwer Health

    Dr Matthew C Gage

  19. Endothelium-specific insulin resistance leads to accelerated atherosclerosis in areas with disturbed flow patterns: A role for reactive oxygen species

    Article • Atherosclerosis, September 2013, Elsevier

    Dr Matthew C Gage

  20. Nox2 NADPH Oxidase Has a Critical Role in Insulin Resistance-Related Endothelial Cell Dysfunction

    Article • Diabetes, January 2013, American Diabetes Association

    Dr Matthew C Gage

  21. Novel Role of the IGF-1 Receptor in Endothelial Function and Repair: Studies in Endothelium-Targeted IGF-1 Receptor Transgenic Mice

    Article • Diabetes, June 2012, American Diabetes Association

    Dr Matthew C Gage

  22. Increasing Circulating IGFBP1 Levels Improves Insulin Sensitivity, Promotes Nitric Oxide Production, Lowers Blood Pressure, and Protects Against Atherosclerosis

    Article • Diabetes, February 2012, American Diabetes Association

    Adil Rajwani, Dr Matthew C Gage

  23. The Insulin-Like Growth Factor-1 Receptor Is a Negative Regulator of Nitric Oxide Bioavailability and Insulin Sensitivity in the Endothelium

    Article • Diabetes, June 2011, American Diabetes Association

    Adil Rajwani, Dr Matthew C Gage

  24. Insulin Resistance Impairs Circulating Angiogenic Progenitor Cell Function and Delays Endothelial Regeneration

    Article • Diabetes, February 2011, American Diabetes Association

    Adil Rajwani, Dr Matthew C Gage

  25. Vascular Insulin-Like Growth Factor-I Resistance and Diet-Induced Obesity

    Article • Endocrinology, October 2009, Endocrine Society

    Adil Rajwani, Dr Matthew C Gage

  26. Proteomic Analysis of IgE-Mediated Secretion by LAD2 Mast Cells

    Article • Journal of Proteome Research, June 2009, American Chemical Society (ACS)

    Dr Matthew C Gage

  27. Proteomic Screening of a Cell Line Model of Esophageal Carcinogenesis Identifies Cathepsin D and Aldo-Keto Reductase 1C2 and 1B10 Dysregulation in Barrett’s Esophagus and Esophageal Adenocarcinoma

    Article • Journal of Proteome Research, April 2008, American Chemical Society (ACS)

    Dr Matthew C Gage