All Stories

  1. Safety and pharmacokinetics of PF-04360365 following a single-dose intravenous infusion in Japanese subjects with mild-to-moderate Alzheimer’s disease: a multicenter, randomized, double-blind, placebo-controlled, dose-escalation study

    Article • International Journal of Clinical Pharmacology and Therapeutics, December 2013, Dustri-Verlgag Dr. Karl Feistle

    Dr Martin M Bednar

  2. P4–299: Chronic ponezumab treatment reduces brain vascular amyloid in the PS1APP mouse model

    Article • Alzheimer s & Dementia, July 2013, Wiley

    Dr Martin M Bednar

  3. Safety and Pharmacology of Ponezumab (PF-04360365) After a Single 10-Minute Intravenous Infusion in Subjects With Mild to Moderate Alzheimer Disease

    Article • Clinical Neuropharmacology, January 2013, Wolters Kluwer Health

    Dr Martin M Bednar

  4. Safety and Pharmacology of a Single Intravenous Dose of Ponezumab in Subjects With Mild-to-Moderate Alzheimer Disease

    Article • Clinical Neuropharmacology, January 2013, Wolters Kluwer Health

    Dr Martin M Bednar

  5. O3‐13‐04: Effect of acute anti‐amyloid monoclonal antibody ponezumab (PF‐04360365) dosing on Aβ fractional clearance rate in subjects with mild Alzheimer's disease and in healthy volunteers

    Article • Alzheimer s & Dementia, July 2012, Wiley

    Dr Martin M Bednar

  6. P4‐208: Safety, efficacy, pharmacokinetics and pharmacodynamics of multiple doses of Ponezumab in subjects with mild‐to‐moderate Alzheimer's disease

    Article • Alzheimer s & Dementia, July 2012, Wiley

    Dr Martin M Bednar

  7. P4‐209: Safety, tolerability, pharmacokinetics and pharmacodynamics of monthly and quarterly doses of Ponezumab (PF‐04360365) in subjects with mild‐to‐moderate Alzheimer's disease

    Article • Alzheimer s & Dementia, July 2012, Wiley

    Dr Martin M Bednar

  8. Neurorestoration therapeutics for neurodegenerative and psychiatric disease

    Article • Neurological Research, March 2012, Taylor & Francis

    Dr Martin M Bednar

  9. Amyloid-related imaging abnormalities in amyloid-modifying therapeutic trials: Recommendations from the Alzheimer’s Association Research Roundtable Workgroup

    Article • Alzheimer s & Dementia, July 2011, Elsevier

    Dr Martin M Bednar

  10. Stem Cell Therapy as an Emerging Paradigm for Stroke (STEPS) II

    Article • Stroke, March 2011, Wolters Kluwer Health

    Dr Martin M Bednar, Donald Phinney

  11. Design and dementia

    Article • November 2010, Taylor & Francis

    Dr Martin M Bednar

  12. Stroke: Working toward a Prioritized World Agenda

    Article • International Journal of Stroke, July 2010, SAGE Publications

    Dr Martin M Bednar

  13. O3‐07‐05: Pharmacokinetics and pharmacodynamics of ponezumab (PF‐04360365) following a single‐dose intravenous infusion in patients with mild to moderate Alzheimer's disease

    Article • Alzheimer s & Dementia, July 2010, Wiley

    Dr Martin M Bednar

  14. P4‐118: Safety and Pharmacokinetics Following a Single Infusion of the Anti‐amyloid Monoclonal Antibody Ponezumab (pf‐04360365) in Patients With Mild‐to‐moderate Alzheimer's Disease: Final Results

    Article • Alzheimer s & Dementia, July 2010, Wiley

    Dr Martin M Bednar

  15. P1‐440: Pharmacokinetics of ponezumab (PF‐04360365) following a single‐dose intravenous infusion in Japanese patients with mild‐to‐moderate Alzheimer's disease: Preliminary results

    Article • Alzheimer s & Dementia, July 2010, Wiley

    Dr Martin M Bednar

  16. P1‐454: Safety of the anti‐amyloid monoclonal antibody ponezumab (PF‐04360365) following a single‐dose intravenous infusion in Japanese patients with mild‐to‐moderate Alzheimer's disease: Preliminary results

    Article • Alzheimer s & Dementia, July 2010, Wiley

    Dr Martin M Bednar

  17. P1‐459: IP/MS analysis of human CSF Aβ following a single dose of the C‐terminal anti‐Aβ antibody ponezumab (PF‐04360365) to Alzheimer patients

    Article • Alzheimer s & Dementia, July 2010, Wiley

    Dr Martin M Bednar

  18. P2‐372: The prevalence of brain microhemorrhages and infarcts in a cohort of patients with mild‐to‐moderate Alzheimer's disease

    Article • Alzheimer s & Dementia, July 2010, Wiley

    Dr Martin M Bednar

  19. P3‐450: Safety and pharmacokinetics following a single 10‐minute intravenous infusion of the anti‐amyloid mAb ponezumab (PF‐04360365) in patients with mild to moderate Alzheimer's disease

    Article • Alzheimer s & Dementia, July 2010, Wiley

    Dr Martin M Bednar

  20. Stroke: Working toward a Prioritized World Agenda

    Article • Cerebrovascular Diseases, January 2010, Karger Publishers

    Dr Martin M Bednar

  21. P1‐262: Preliminary population pharmacokinetic modeling of PF‐04360365, a humanized anti‐amyloid monoclonal antibody, in patients with mild‐to‐moderate Alzheimer's disease

    Article • Alzheimer s & Dementia, July 2009, Wiley

    Dr Martin M Bednar

  22. O4‐04‐03: Safety and pharmacokinetics of the anti‐amyloid monoclonal antibody PF‐04360365 following a single infusion in patients with mild‐to‐moderate Alzheimer's disease: Preliminary results

    Article • Alzheimer s & Dementia, July 2009, Wiley

    Dr Martin M Bednar

  23. Specific impairments in visuospatial working and short-term memory following low-dose scopolamine challenge in healthy older adults

    Article • Neuropsychologia, August 2008, Elsevier

    Dr Martin M Bednar

  24. Off-Pump Versus On-Pump Coronary Artery Surgery

    Article • International Heart Journal, January 2007, International Heart Journal (Japanese Heart Journal)

    Dr Martin M Bednar

  25. Interventions for heart disease and their effects on Alzheimer's disease

    Article • Neurological Research, September 2006, Taylor & Francis

    Dr Martin M Bednar

  26. Reversal of scopolamine‐induced deficits with a single dose of donepezil, an acetylcholinesterase inhibitor

    Article • Alzheimer s & Dementia, October 2005, Wiley

    Dr Martin M Bednar

  27. Groton Maze Learning Test

    Article • January 2005, American Psychological Association (APA)

    Dr Martin M Bednar

  28. P2-253 Risk of Alzheimer's disease diagnosis following coronary artery bypass graft surgery versus percutaneous transluminal coronary angioplasty

    Article • Neurobiology of Aging, July 2004, Elsevier

    Dr Martin M Bednar

  29. S1-03-06 Reduced incidence of Alzheimer's disease among subjects exposed to general anesthesia in non-cardiac operations: a retrospective analysis

    Article • Neurobiology of Aging, July 2004, Elsevier

    Dr Martin M Bednar

  30. Prevention of Venous Thromboembolism in the Acute Treatment Phase after Spinal Cord Injury

    Article • Journal of Trauma and Acute Care Surgery, June 2003, Wolters Kluwer Health

    Dr Martin M Bednar, Mark Hamilton

  31. Torsades de pointes associated with nonantiarrhythmic drugs and observations on gender and QTc

    Article • The American Journal of Cardiology, June 2002, Elsevier

    Dr Martin M Bednar

  32. Combining antiplatelet and thrombolytic therapies for stroke

    Article • Expert Opinion on Pharmacotherapy, April 2002, Informa Healthcare

    Dr Martin M Bednar

  33. Effect of Medium Tonicity and Dextran on Neutrophil Function In Vitro

    Article • Journal of Trauma and Acute Care Surgery, February 2002, Wolters Kluwer Health

    Dr Martin M Bednar

  34. The effect of vasodilators on aspirin-induced antagonism of t-PA thrombolysis

    Article • Neurological Research, October 2001, Taylor & Francis

    Dr Martin M Bednar

  35. The QT interval

    Article • Progress in Cardiovascular Diseases, April 2001, Elsevier

    Dr Martin M Bednar

  36. The QT interval☆

    Article • Progress in Cardiovascular Diseases, March 2001, Elsevier

    Dr Martin M Bednar

  37. 16(R)-Hydroxyeicosatetraenoic Acid, a Novel Cytochrome P450 Product of Arachidonic Acid, Suppresses Activation of Human Polymorphonuclear Leukocytes and Reduces Intracranial Pressure in a Rabbit Model of Thromboembolic Stroke

    Article • Neurosurgery, December 2000, Wolters Kluwer Health

    Dr Martin M Bednar

  38. 16(R)-hydroxy-5,8,11,14-eicosatetraenoic acid, a new arachidonate metabolite in human polymorphonuclear leukocytes

    Article • Biochemical Pharmacology, August 2000, Elsevier

    Dr Martin M Bednar

  39. Stroke: antithrombin versus antiplatelet therapy

    Article • Expert Opinion on Investigational Drugs, February 2000, Informa Healthcare

    Dr Martin M Bednar

  40. Antiplatelet Therapy in Acute Cerebral Ischemia

    Article • Stroke, April 1999, Wolters Kluwer Health

    Dr Martin M Bednar

  41. Complement depletion does not reduce brain injury in a rabbit model of thromboembolic stroke

    Article • Brain Research Bulletin, February 1999, Elsevier

    Dr Martin M Bednar

  42. Preoperative Volume Expansion Improves Tolerance to Carotid Artery Cross-Clamping during Endarterectomy

    Article • Neurosurgery, August 1998, Wolters Kluwer Health

    Dr Martin M Bednar

  43. HYPERTONIC SALINE SUPPRESSES ACTIVATION OF STIMULATED HUMAN NEUTROPHILS.

    Article • Shock, June 1998, Wolters Kluwer Health

    Dr Martin M Bednar

  44. Evaluation of Cerebral Vasospasm after Early Surgical and Endovascular Treatment of Ruptured Intracranial Aneurysms

    Article • Neurosurgery, February 1998, Wolters Kluwer Health

    Dr Martin M Bednar

  45. Antineutrophil strategies

    Article • Neurology, November 1997, Wolters Kluwer Health

    Dr Martin M Bednar

  46. Nitric Oxide Reverses Aspirin Antagonism of t-PA Thrombolysis in a Rabbit Model of Thromboembolic Stroke

    Article • Experimental Neurology, August 1997, Elsevier

    Dr Martin M Bednar

  47. Activation of complement by tissue plasminogen activator, but not acute cerebral ischemia, in a rabbit model of thromboembolic stroke

    Article • January 1997, Journal of Neurosurgery Publishing Group (JNSPG)

    Dr Martin M Bednar

  48. Delayed adjuvant therapy with the 21-aminosteroid U74006F and the anion channel blocker L644-711 does not improve outcome following thrombolytic therapy in a rabbit model of thromboembolic stroke

    Article • Surgical Neurology, January 1997, Elsevier

    Dr Martin M Bednar

  49. The Effect of Oral Antiplatelet Agents on Tissue Plasminogen Activator-mediated Thrombolysis in a Rabbit Model of Thromboembolic Stroke

    Article • Neurosurgery, August 1996, Wolters Kluwer Health

    Dr Martin M Bednar

  50. Systemic Complement Depletion Inhibits Experimental Cerebral Vasospasm

    Article • Neurosurgery, July 1996, Wolters Kluwer Health

    Dr Martin M Bednar

  51. U83836E Reduces Secondary Brain Injury in a Rabbit Model of Cryogenic Trauma

    Article • September 1995, Wolters Kluwer Health

    Dr Martin M Bednar

  52. Delayed Tissue-Plasminogen Activator Therapy in a Rabbit Model of Thromboembolic Stroke

    Article • Neurosurgery, June 1995, Wolters Kluwer Health

    Dr Martin M Bednar

  53. Delayed Tissue-Plasminogen Activator Therapy in a Rabbit Model of Thromboembolic Stroke

    Article • Neurosurgery, June 1995, Wolters Kluwer Health

    Dr Martin M Bednar

  54. Ticlopidine augments luminol‐dependent chemiluminescence in human neutrophils

    Article • Journal of Bioluminescence and Chemiluminescence, March 1995, Wiley

    Dr Martin M Bednar

  55. Neutrophil and platelet activity and quantification following delayed tPA therapy in a rabbit model of thromboembolic stroke

    Article • Journal of Thrombosis and Thrombolysis, January 1995, Springer Science + Business Media

    Dr Martin M Bednar

  56. The Effect of the 21-Aminosteroid U74006F in a Rabbit Model of Thromboembolic Stroke

    Article • Neurosurgery, November 1992, Wolters Kluwer Health

    Dr Martin M Bednar

  57. The Effect of the 21-Aminosteroid U74006F in a Rabbit Model of Thromboembolic Stroke

    Article • Neurosurgery, November 1992, Wolters Kluwer Health

    Dr Martin M Bednar

  58. Primary central nervous system T-cell lymphoma

    Article • April 1991, Journal of Neurosurgery Publishing Group (JNSPG)

    Dr Martin M Bednar

  59. Role of leukocytes and 5-lipoxygenase products in induction of cerebral edema

    Article • Neurosurgery, February 1990, Wolters Kluwer Health

    Dr Martin M Bednar

  60. Traumatic intraspinal pneumocele

    Article • Surgical Neurology, June 1987, Elsevier

    Dr Martin M Bednar

  61. Arachidonic acid monooxygenase and lipoxygenase activities in polymorphonuclear leukocytes

    Article • Biochemical Pharmacology, May 1987, Elsevier

    Dr Martin M Bednar

  62. Neutrophil Depletion Suppresses 111In-Labeled Platelet Accumulation in Infarcted Myocardium

    Article • Journal of Cardiovascular Pharmacology, September 1985, Wolters Kluwer Health

    Dr Martin M Bednar

  63. Conversion of arachidonic acid to two novel products by a cytochrome P450-dependent mixed-function oxidase in polymorphonuclear leukocytes

    Article • Biochemical and Biophysical Research Communications, September 1984, Elsevier

    Dr Martin M Bednar