All Stories

  1. Development of Bright and Biocompatible Nanoruby and Its Application to Background-Free Time-Gated Imaging of G-Protein-Coupled Receptors

    Article • ACS Applied Materials & Interfaces, November 2017, American Chemical Society (ACS)

    Professor Mark Connor

  2. Cannabinoid CB1 and CB2 Receptor Signaling and Bias

    Article • Cannabis and Cannabinoid Research, April 2017, Mary Ann Liebert Inc

    Professor Mark Connor

  3. Accelerating the search for the missing proteins in the human proteome

    Article • Nature Communications, January 2017, Nature

    Professor Mark Connor

  4. Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity

    Article • Nature Communications, January 2017, Nature

    Professor Mark Connor

  5. Pharmacology of Valinate andtert-Leucinate Synthetic Cannabinoids 5F-AMBICA, 5F-AMB, 5F-ADB, AMB-FUBINACA, MDMB-FUBINACA, MDMB-CHMICA, and Their Analogues

    Article • ACS Chemical Neuroscience, September 2016, American Chemical Society (ACS)

    Professor Mark Connor

  6. Front Cover: Wide-field time-gated photoluminescence microscopy for fast ultrahigh-sensitivity imaging of photoluminescent probes (J. Biophotonics 8/2016)

    Article • Journal of Biophotonics, August 2016, Wiley

    Professor Mark Connor

  7. Wide-field time-gated photoluminescence microscopy for fast ultrahigh-sensitivity imaging of photoluminescent probes

    Article • Journal of Biophotonics, June 2016, Wiley

    Professor Mark Connor

  8. The 2-alkyl-2H-indazole regioisomers of synthetic cannabinoids AB-CHMINACA, AB-FUBINACA, AB-PINACA, and 5F-AB-PINACA are possible manufacturing impurities with cannabimimetic activities

    Article • Forensic Toxicology, April 2016, Springer Science + Business Media

    Professor Mark Connor

  9. Flexible analogues of WAY-267,464: Synthesis and pharmacology at the human oxytocin and vasopressin 1a receptors

    Article • European Journal of Medicinal Chemistry, January 2016, Elsevier

    Professor Mark Connor

  10. Identification ofN-arachidonoyl dopamine as a highly biased ligand at cannabinoid CB1receptors

    Article • British Journal of Pharmacology, November 2015, Wiley

    Professor Mark Connor

  11. Pharmacology of Indole and Indazole Synthetic Cannabinoid Designer Drugs AB-FUBINACA, ADB-FUBINACA, AB-PINACA, ADB-PINACA, 5F-AB-PINACA, 5F-ADB-PINACA, ADBICA, and 5F-ADBICA

    Article • ACS Chemical Neuroscience, September 2015, American Chemical Society (ACS)

    Professor Mark Connor

  12. Effects of Bioisosteric Fluorine in Synthetic Cannabinoid Designer Drugs JWH-018, AM-2201, UR-144, XLR-11, PB-22, 5F-PB-22, APICA, and STS-135

    Article • ACS Chemical Neuroscience, August 2015, American Chemical Society (ACS)

    Professor Mark Connor

  13. Distinct Temporal Fingerprint for Cyclic Adenosine Monophosphate (cAMP) Signaling of Indole-2-carboxamides as Allosteric Modulators of the Cannabinoid Receptors

    Article • Journal of Medicinal Chemistry, August 2015, American Chemical Society (ACS)

    Professor Mark Connor

  14. Structure–activity relationships of synthetic cannabinoid designer drug RCS-4 and its regioisomers and C4 homologues

    Article • Forensic Toxicology, May 2015, Springer Science + Business Media

    Professor Mark Connor

  15. A6V polymorphism of the human μ-opioid receptor decreases signalling of morphine and endogenous opioidsin vitro

    Article • British Journal of Pharmacology, March 2015, Wiley

    Professor Mark Connor

  16. Themed section

    Article • British Journal of Pharmacology, December 2014, Wiley

    Macdonald Christie, Professor Mark Connor

  17. Fluorescence-Based, High-Throughput Assays for μ-Opioid Receptor Activation Using a Membrane Potential-Sensitive Dye

    Article • September 2014, Springer Science + Business Media

    Professor Mark Connor

  18. Nordihydroguaiaretic acid activates hTRPA1 and modulates behavioral responses to noxious cold in mice

    Article • Pharmacology Research & Perspectives, September 2014, Wiley

    Professor Mark Connor

  19. Buprenorphine signalling is compromised at the N40D polymorphism of the human μ opioid receptor in vitro

    Article • British Journal of Pharmacology, August 2014, Wiley

    Professor Mark Connor

  20. Cellular signalling of non‐synonymous single‐nucleotide polymorphisms of the human μ‐opioid receptor (OPRM1)

    Article • British Journal of Pharmacology, July 2014, Wiley

    Professor Mark Connor

  21. β‐Arrestin‐2 knockout prevents development of cellular μ‐opioid receptor tolerance but does not affect opioid‐withdrawal‐related adaptations in single PAG neurons

    Article • British Journal of Pharmacology, July 2014, Wiley

    Macdonald Christie, Professor Mark Connor

  22. A Real-Time, Fluorescence-Based Assay for Measuring µ-Opioid Receptor Modulation of Adenylyl Cyclase Activity in Chinese Hamster Ovary Cells

    Article • SLAS DISCOVERY, February 2014, SAGE Publications

    Professor Mark Connor

  23. Ligand determinants of fatty acid activation of the pronociceptive ion channel TRPA1

    Article • PeerJ, January 2014, PeerJ

    Professor Mark Connor

  24. Real-time characterization of cannabinoid receptor 1 (CB1) allosteric modulators reveals novel mechanism of action

    Article • British Journal of Pharmacology, October 2013, Wiley

    Professor Mark Connor

  25. The Synthesis and Pharmacological Evaluation of Adamantane-Derived Indoles: Cannabimimetic Drugs of Abuse

    Article • ACS Chemical Neuroscience, July 2013, American Chemical Society (ACS)

    Professor Mark Connor

  26. A Continuous, Fluorescence-based Assay of µ-Opioid Receptor Activation in AtT-20 Cells

    Article • SLAS DISCOVERY, March 2013, SAGE Publications

    Professor Mark Connor

  27. Inhibition of human recombinant T-type calcium channels byN-arachidonoyl 5-HT

    Article • British Journal of Pharmacology, October 2012, Wiley

    Professor Mark Connor

  28. Targeting somatostatin receptors using in situ-bioconjugated fluorescent nanoparticles

    Article • Nanomedicine, October 2012, Future Medicine

    Professor Mark Connor

  29. What would 5-HT do? Regional diversity of 5-HT1 receptor modulation of primary afferent neurotransmission

    Article • British Journal of Pharmacology, August 2012, Wiley

    Professor Mark Connor

  30. TRPV1 Antagonists as a Potential Treatment for Hyperalgesia

    Article • Recent Patents on CNS Drug Discovery, July 2012, Bentham Science Publishers

    Professor Mark Connor

  31. Sex differences in the expression of serotonin-synthesizing enzymes in mouse trigeminal ganglia

    Article • Neuroscience, December 2011, Elsevier

    Professor Mark Connor

  32. Trigeminal ganglion neuron subtype-specific alterations of CaV2.1 calcium current and excitability in a Cacna1a mouse model of migraine

    Article • The Journal of Physiology, November 2011, Wiley

    Professor Mark Connor

  33. Pharmacological Characterization of a Recombinant, Fluorescent Somatostatin Receptor Agonist

    Article • Bioconjugate Chemistry, September 2011, American Chemical Society (ACS)

    Professor Mark Connor

  34. Interfacing nanodiamonds for single molecular optical-biomedical imaging

    Article • August 2011, Institute of Electrical & Electronics Engineers (IEEE)

    Professor Mark Connor

  35. The results of an experimental indoor hydroponic Cannabis growing study, using the ‘Screen of Green’ (ScrOG) method—Yield, tetrahydrocannabinol (THC) and DNA analysis

    Article • Forensic Science International, October 2010, Elsevier

    Professor Mark Connor

  36. N-Acyl amino acids and N-acyl neurotransmitter conjugates: neuromodulators and probes for new drug targets

    Article • British Journal of Pharmacology, May 2010, Wiley

    Professor Mark Connor

  37. Constitutively Active μ-Opioid Receptors

    Article • January 2010, Elsevier

    Professor Mark Connor

  38. Shadows across μ-Star? Constitutively active μ-opioid receptors revisited

    Article • British Journal of Pharmacology, March 2009, Wiley

    Professor Mark Connor

  39. Inhibition of human recombinant T-type calcium channels by the endocannabinoid N-arachidonoyl dopamine

    Article • British Journal of Pharmacology, March 2009, Wiley

    Professor Mark Connor

  40. Decreased μ-opioid receptor signalling and a reduction in calcium current density in sensory neurons from chronically morphine-treated mice

    Article • British Journal of Pharmacology, January 2009, Wiley

    Professor Mark Connor

  41. Allopurinol for pain relief: more than just crystal clearance?

    Article • British Journal of Pharmacology, January 2009, Wiley

    Professor Mark Connor

  42. Sumatriptan Inhibits Synaptic Transmission in the Rat Midbrain Periaqueductal Grey

    Article • Molecular Pain, September 2008, SAGE Publications

    Professor Mark Connor

  43. Inhibition of Recombinant Human T-type Calcium Channels by  9-Tetrahydrocannabinol and Cannabidiol

    Article • Journal of Biological Chemistry, April 2008, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Mark Connor

  44. Methanandamide activation of a novel current in mouse trigeminal ganglion sensory neurons in vitro

    Article • Neuropharmacology, January 2008, Elsevier

    Professor Mark Connor

  45. Towards a Receptor for Nocistatin?

    Article • British Journal of Pharmacology, October 2007, Wiley

    Professor Mark Connor

  46. Lack of functional expression of NMDA receptors in PC12 cells

    Article • NeuroToxicology, July 2007, Elsevier

    Professor Mark Connor

  47. The Role of Opioid Receptor Phosphorylation and Trafficking in Adaptations to Persistent Opioid Treatment

    Article • Neurosignals, June 2006, Karger Publishers

    Professor Mark Connor

  48. Has the sun set onκ3-opioid receptors?

    Article • British Journal of Pharmacology, February 2006, Wiley

    Professor Mark Connor

  49. TRPV1 Antagonists as a Potential Treatment for Hyperalgesia

    Article • Recent Patents on CNS Drug Discovery, January 2006, Bentham Science Publishers

    Professor Mark Connor

  50. Opioid tolerance in periaqueductal gray neurons isolated from mice chronically treated with morphine

    Article • British Journal of Pharmacology, September 2005, Wiley

    Professor Mark Connor

  51. Humanizing mice: catching up with elusive B1 receptors

    Article • British Journal of Pharmacology, April 2005, Wiley

    Professor Mark Connor

  52. Opioids: cellular mechanisms of tolerance and physical dependence

    Article • Current Opinion in Pharmacology, February 2005, Elsevier

    Professor Mark Connor

  53. Contrasting Phenotypes of Putative Proprioceptive and Nociceptive Trigeminal Neurons Innervating Jaw Muscle in Rat

    Article • Molecular Pain, January 2005, SAGE Publications

    Professor Mark Connor

  54. δ-opioid receptor-mediated actions on rostral ventromedial medulla neurons

    Article • Neuroscience, January 2005, Elsevier

    Professor Mark Connor

  55. μ-Opioid receptor desensitization: Is morphine different?

    Article • British Journal of Pharmacology, November 2004, Wiley

    Professor Mark Connor

  56. Cellular actions of somatostatin on rat periaqueductal grey neuronsin vitro

    Article • British Journal of Pharmacology, August 2004, Wiley

    Professor Mark Connor

  57. Convulsant actions of calycanthine

    Article • Toxicology and Applied Pharmacology, July 2003, Elsevier

    Professor Mark Connor

  58. Opioid Agonists Have Different Efficacy Profiles for G Protein Activation, Rapid Desensitization, and Endocytosis of Mu-opioid Receptors

    Article • Journal of Biological Chemistry, March 2003, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Mark Connor

  59. Gingerols: a novel class of vanilloid receptor (VR1) agonists

    Article • British Journal of Pharmacology, November 2002, Wiley

    Professor Mark Connor

  60. Anandamide is a partial agonist at native vanilloid receptors in acutely isolated mouse trigeminal sensory neurons

    Article • British Journal of Pharmacology, October 2002, Wiley

    Professor Mark Connor

  61. Capsaicin activation of glutamatergic synaptic transmission in the rat locus coeruleusIn vitro

    Article • The Journal of Physiology, September 2002, Wiley

    Professor Mark Connor

  62. Prostaglandin E2inhibits calcium current in two sub-populations of acutely isolated mouse trigeminal sensory neurons

    Article • The Journal of Physiology, March 2002, Wiley

    Professor Mark Connor

  63. Nociceptin inhibits calcium channel currents in a subpopulation of small nociceptive trigeminal ganglion neurons in mouse

    Article • The Journal of Physiology, October 2001, Wiley

    Professor Mark Connor

  64. Actions of nociceptin/orphanin FQ and other prepronociceptin products on rat rostral ventromedial medulla neuronsin vitro

    Article • The Journal of Physiology, August 2001, Wiley

    Professor Mark Connor

  65. Cellular Actions Of Opioids And Other Analgesics: Implications For Synergism In Pain Relief

    Article • Clinical and Experimental Pharmacology and Physiology, July 2000, Wiley

    Professor Mark Connor

  66. Article • Nature Structural Biology, June 2000, Nature

    Professor Mark Connor

  67. Isolation and pharmacological characterisation of δ-atracotoxin-Hv1b, a vertebrate-selective sodium channel toxin

    Article • FEBS Letters, March 2000, Wiley

    Professor Mark Connor

  68. Isolation of a funnel-web spider polypeptide with homology to mamba intestinal toxin 1 and the embryonic head inducer Dickkopf-1

    Article • Toxicon, March 2000, Elsevier

    Professor Mark Connor

  69. Continued morphine modulation of calcium channel currents in acutely isolated locus coeruleus neurons from morphine-dependent rats

    Article • British Journal of Pharmacology, December 1999, Wiley

    Professor Mark Connor

  70. High-resolution solution structure of gurmarin, a sweet-taste-suppressing plant polypeptide

    Article • European Journal of Biochemistry, September 1999, Wiley

    Professor Mark Connor

  71. OPIOID RECEPTOR SIGNALLING MECHANISMS

    Article • Clinical and Experimental Pharmacology and Physiology, July 1999, Wiley

    Professor Mark Connor

  72. Article • Perspectives in Drug Discovery and Design, January 1999, Springer Science + Business Media

    Professor Mark Connor

  73.  -Atracotoxins from Australian Funnel-web Spiders Compete with Scorpion  -Toxin Binding but Differentially Modulate Alkaloid Toxin Activation of Voltage-gated Sodium Channels

    Article • Journal of Biological Chemistry, October 1998, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Mark Connor

  74. Modulation of Ca2+channel currents of acutely dissociated rat periaqueductal grey neurons

    Article • The Journal of Physiology, May 1998, Wiley

    Professor Mark Connor

  75. Article • Nature, December 1997, Nature

    Professor Mark Connor

  76. Cortistatin increase of a potassium conductance in rat locus coeruleusin vitro

    Article • British Journal of Pharmacology, December 1997, Wiley

    Professor Mark Connor

  77. Chronic ethanol promotes the neuronal differentiation of NG108-15 cells independently of toxin-sensitive G-proteins

    Article • Environmental Toxicology and Pharmacology, September 1997, Elsevier

    Professor Mark Connor

  78. The structure of a novel insecticidal neurotoxin, ω-atracotoxin-HV1, from the venom of an Australian funnel web spider

    Article • Nature Structural Biology, July 1997, Nature

    Professor Mark Connor

  79. Neuropeptide Y Y2 receptor and somatostatin sst2 receptor coupling to mobilization of intracellular calcium in SH‐SY5Y human neuroblastoma cells

    Article • British Journal of Pharmacology, January 1997, Wiley

    Professor Graeme Henderson, Professor Mark Connor

  80. Bradykinin Inhibition of N- and L-type Calcium Channel Currents in NG108-15 Cells

    Article • Neuropharmacology, January 1997, Elsevier

    Professor Mark Connor

  81. δ-opioid Receptor Mobilization of Intracellular Calcium in SH-SY5Y Cells: Lack of Evidence for δ-receptor Subtypes

    Article • Neuropharmacology, January 1997, Elsevier

    Professor Mark Connor

  82. Nociceptin receptor coupling to a potassium conductance in rat locus coeruleus neurones in vitro

    Article • British Journal of Pharmacology, December 1996, Wiley

    Professor Mark Connor

  83. The effect of nociceptin on Ca2+ channel current and intracellular Ca2+ in the SH‐SY5Y human neuroblastoma cell line

    Article • British Journal of Pharmacology, May 1996, Wiley

    Professor Graeme Henderson, Professor Mark Connor

  84. δ‐ and μ‐opioid receptor mobilization of intracellular calcium in SH‐SY5Y human neuroblastoma cells

    Article • British Journal of Pharmacology, January 1996, Wiley

    Professor Graeme Henderson, Professor Mark Connor

  85. δ and μ opioid receptor mobilization of intracellular calcium in neuroblastoma cells

    Article • Regulatory Peptides, November 1994, Elsevier

    Professor Mark Connor

  86. Oocytes from Xenopus laevis contain an intrinsic σ2-like binding site

    Article • Neuroscience Letters, October 1994, Elsevier

    Professor Mark Connor

  87. Focal stimulation of specific pathways in the rat hippocampus causes a reduction in radioligand binding to the haloperidol-sensitive sigma receptor

    Article • Experimental Brain Research, July 1991, Springer Science + Business Media

    Professor Mark Connor

  88. Frequency-dependent neuromuscular blockade by textilotoxin in vivo

    Article • Toxicon, January 1991, Elsevier

    Professor Mark Connor