All Stories

  1. In Vitro Evaluation of Eudragit Matrices for Oral Delivery of BCG Vaccine to Animals

    Article • April 2019, MDPI AG

    Dr Mark Andrew Chambers

  2. A bilayer tissue culture model of the bovine alveolus

    Article • F1000Research, April 2019, Faculty of 1000, Ltd.

    Dr Mark Andrew Chambers

  3. Isolation and characterisation of alveolar type II pneumocytes from adult bovine lung

    Article • Scientific Reports, August 2018, Springer Science + Business Media

    Dr Mark Andrew Chambers

  4. Quantitative interferon-gamma responses predict future disease progression in badgers naturally infected with Mycobacterium bovis

    Article • Epidemiology and Infection, October 2017, Cambridge University Press

    Dr Julian A Drewe, Dr Mark Andrew Chambers

  5. Field evaluation of candidate baits for oral delivery of BCG vaccine to European badgers, Meles meles

    Article • Vaccine, August 2017, Elsevier

    Dr Mark Andrew Chambers

  6. Testing of a palatable bait and compatible vaccine carrier for the oral vaccination of European badgers (Meles meles) against tuberculosis

    Article • Vaccine, February 2017, Elsevier

    Dr Mark Andrew Chambers

  7. The Effect of Oral Vaccination with Mycobacterium bovis BCG on the Development of Tuberculosis in Captive European Badgers (Meles meles)

    Article • Frontiers in Cellular and Infection Microbiology, January 2017, Frontiers

    Dr Mark Andrew Chambers

  8. Behaviour of European badgers and non-target species towards candidate baits for oral delivery of a tuberculosis vaccine

    Article • Preventive Veterinary Medicine, December 2016, Elsevier

    Dr Mark Andrew Chambers

  9. Diagnosis of tuberculosis in groups of badgers: an exploration of the impact of trapping efficiency, infection prevalence and the use of multiple tests

    Article • Epidemiology and Infection, January 2016, Cambridge University Press

    Dr Julian A Drewe, Dr Mark Andrew Chambers

  10. Challenges in Veterinary Vaccine Development and Immunization

    Article • January 2016, Springer Science + Business Media

    Dr Mark Andrew Chambers

  11. Host-directed therapy targeting the Mycobacterium tuberculosis granuloma: a review

    Article • Seminars in Immunopathology, October 2015, Springer Science + Business Media

    Dr Mark Andrew Chambers

  12. Discovery of a polyomavirus in European badgers (Meles meles) and the evolution of host range in the family Polyomaviridae

    Article • Journal of General Virology, June 2015, Society for General Microbiology

    Dr Mark Andrew Chambers

  13. Exposure of nontarget wildlife to candidate TB vaccine baits deployed for European badgers

    Article • European Journal of Wildlife Research, January 2015, Springer Science + Business Media

    Dr Mark Andrew Chambers

  14. Association of quantitative interferon-γresponses with the progression of naturally acquiredMycobacterium bovisinfection in wild European badgers (Meles meles)

    Article • Immunology, January 2015, Wiley

    Dr Mark Andrew Chambers

  15. Tuberculosis, leprosy and mycobacterial diseases of man and animals: the many hosts of mycobacteria

    Article • January 2015, CABI Publishing

    Dr Mark Andrew Chambers

  16. Vaccination against tuberculosis in badgers and cattle: an overview of the challenges, developments and current research priorities in Great Britain

    Article • Veterinary Record, July 2014, BMJ

    Dr Mark Andrew Chambers

  17. Oral vaccination of badgers (Meles meles) against tuberculosis: Comparison of the protection generated by BCG vaccine strains Pasteur and Danish

    Article • The Veterinary Journal, June 2014, Elsevier

    Dr Mark Andrew Chambers

  18. Review of the Diagnosis of Tuberculosis in Non-Bovid Wildlife Species Using Immunological Methods - An Update of Published Work Since 2009

    Article • Transboundary and Emerging Diseases, October 2013, Wiley

    Dr Mark Andrew Chambers

  19. Sex-Related Heterogeneity in the Life-History Correlates ofMycobacterium bovisInfection in European Badgers (Meles meles)

    Article • Transboundary and Emerging Diseases, October 2013, Wiley

    Dr Mark Andrew Chambers

  20. Spatial relationships between Eurasian badgers (Meles meles) and cattle infected with Mycobacterium bovis in Northern Spain

    Article • The Veterinary Journal, September 2013, Elsevier

    Dr Mark Andrew Chambers, Christian Gortazar

  21. Long-term temporal trends and estimated transmission rates forMycobacterium bovisinfection in an undisturbed high-density badger (Meles meles) population

    Article • Epidemiology and Infection, March 2013, Cambridge University Press

    Dr Mark Andrew Chambers

  22. Heterogeneity in the risk of Mycobacterium bovis infection in European badger (Meles meles) cubs

    Article • Epidemiology and Infection, March 2013, Cambridge University Press

    Dr Mark Andrew Chambers

  23. Evaluation of a method to detectMycobacterium bovisin air samples from infected Eurasian badgers (Meles meles) and their setts

    Article • Letters in Applied Microbiology, March 2013, Wiley

    Dr Mark Andrew Chambers

  24. Rapid and simple detection of ng/mL protein from serum samples

    Article • The Analyst, January 2013, Royal Society of Chemistry

    Jie Jayne Wu, Dr Mark Andrew Chambers

  25. BCG Vaccination Reduces Risk of Tuberculosis Infection in Vaccinated Badgers and Unvaccinated Badger Cubs

    Article • PLoS ONE, December 2012, PLOS

    Dr Mark Andrew Chambers

  26. Method for assessing IFN-γ responses in guinea pigs during TB vaccine trials

    Article • Letters in Applied Microbiology, August 2012, Wiley

    Dr Mark Andrew Chambers

  27. Mycobacterium bovis infection in badger cubs: Re-assessing the evidence for maternally derived immunological protection from advanced disease

    Article • Veterinary Immunology and Immunopathology, August 2012, Elsevier

    Dr Mark Andrew Chambers

  28. Mycobacteria Infections

    Article • July 2012, Wiley

    Dr Mark Andrew Chambers, Christian Gortazar

  29. Development of a device for sampling cattle breath

    Article • Biosystems Engineering, June 2012, Elsevier

    Dr Mark Andrew Chambers

  30. Infection of Eurasian badgers (Meles meles) with Mycobacterium bovis and Mycobacterium avium complex in Spain

    Article • The Veterinary Journal, November 2011, Elsevier

    Dr Iker A Sevilla, Dr Mark Andrew Chambers, Christian Gortazar

  31. Protection of Eurasian badgers (Meles meles) from tuberculosis after intra-muscular vaccination with different doses of BCG

    Article • Vaccine, May 2011, Elsevier

    Dr Mark Andrew Chambers

  32. Bacillus Calmette-Guerin vaccination reduces the severity and progression of tuberculosis in badgers

    Article • Proceedings of the Royal Society B Biological Sciences, December 2010, Royal Society Publishing

    Mark Chambers, Dr Mark Andrew Chambers

  33. Non-acylated Mycobacterium bovis glycoprotein MPB83 binds to TLR1/2 and stimulates production of matrix metalloproteinase 9

    Article • Biochemical and Biophysical Research Communications, September 2010, Elsevier

    Dr Mark Andrew Chambers

  34. Oral vaccination of badgers (Meles meles) with BCG and protective immunity against endobronchial challenge with Mycobacterium bovis

    Article • Vaccine, August 2010, Elsevier

    Dr Mark Andrew Chambers

  35. Transcutaneous immunization with lipid offers a new route of vaccination againstHelicobacter pyloriand a new candidate delivery vehicle

    Article • Expert Review of Vaccines, March 2010, Taylor & Francis

    Dr Mark Andrew Chambers

  36. Pelioid Hepatocellular Carcinoma in an Adult Eurasian Badger (Meles meles)

    Article • Journal of Comparative Pathology, February 2010, Elsevier

    Dr Mark Andrew Chambers

  37. Electronic nose responses and acute phase proteins correlate in blood using a bovine model of respiratory infection☆

    Article • Sensors and Actuators B Chemical, January 2010, Elsevier

    Dr Mark Andrew Chambers

  38. Evaluation of a Rapid Serological Test for the Determination of Mycobacterium bovis Infection in Badgers (Meles meles) Found Dead

    Article • Clinical and Vaccine Immunology, December 2009, ASM Journals

    Dr Mark Andrew Chambers

  39. Evaluation of the CervidTB STAT-PAK for the Detection of Mycobacterium bovis Infection in Wild Deer in Great Britain

    Article • Clinical and Vaccine Immunology, August 2009, ASM Journals

    Dr Mark Andrew Chambers

  40. Review of the Diagnosis and Study of Tuberculosis in Non-Bovine Wildlife Species Using Immunological Methods

    Article • Transboundary and Emerging Diseases, August 2009, Wiley

    Dr Mark Andrew Chambers

  41. A review of infection of wildlife hosts withMycobacterium bovisand the diagnostic difficulties of the ‘no visible lesion’ presentation

    Article • New Zealand Veterinary Journal, June 2009, Taylor & Francis

    Dr Mark Andrew Chambers

  42. Methodological variation in headspace analysis of liquid samples using electronic nose

    Article • Sensors and Actuators B Chemical, June 2009, Elsevier

    Dr Mark Andrew Chambers

  43. Evaluation of a combination of SIFT-MS and multivariate data analysis for the diagnosis of Mycobacterium bovis in wild badgers

    Article • The Analyst, January 2009, Royal Society of Chemistry

    Dr Mark Andrew Chambers

  44. Immunological responses and protective immunity in BCG vaccinated badgers following endobronchial infection with Mycobacterium bovis

    Article • Vaccine, January 2009, Elsevier

    Dr Mark Andrew Chambers

  45. Immunological responses following experimental endobronchial infection of badgers (Meles meles) with different doses of Mycobacterium bovis

    Article • Veterinary Immunology and Immunopathology, January 2009, Elsevier

    Dr Mark Andrew Chambers

  46. Methodological Variability Using Electronic Nose Technology For Headspace Analysis

    Article • January 2009, American Institute of Physics

    Dr Mark Andrew Chambers

  47. Performance of TB immunodiagnostic tests in Eurasian badgers (Meles meles) of different ages and the influence of duration of infection on serological sensitivity

    Article • BMC Veterinary Research, January 2009, Springer Science + Business Media

    Dr Mark Andrew Chambers

  48. Serum Headspace Analysis With An Electronic Nose And Comparison With Clinical Signs Following Experimental Infection Of Cattle With Mannheimia Haemolytica

    Article • January 2009, American Institute of Physics

    Dr Mark Andrew Chambers

  49. Volatile Organic Compound (VOC) Analysis For Disease Detection: Proof Of Principle For Field Studies Detecting Paratuberculosis And Brucellosis

    Article • January 2009, American Institute of Physics

    Dr Mark Andrew Chambers

  50. Animal-side serologic assay for rapid detection of Mycobacterium bovis infection in multiple species of free-ranging wildlife

    Article • Veterinary Microbiology, December 2008, Elsevier

    Dr Mark Andrew Chambers, Christian Gortazar

  51. Assessment of different formulations of oral Mycobacterium bovis Bacille Calmette-Guérin (BCG) vaccine in rodent models for immunogenicity and protection against aerosol challenge with M. bovis

    Article • Vaccine, October 2008, Elsevier

    Dr Mark Andrew Chambers

  52. Oral Vaccination of Guinea Pigs with a Mycobacterium bovis Bacillus Calmette-Guérin Vaccine in a Lipid Matrix Protects against Aerosol Infection with Virulent M. bovis

    Article • Infection and Immunity, June 2008, ASM Journals

    Dr Mark Andrew Chambers

  53. Development and evaluation of a gamma-interferon assay for tuberculosis in badgers (Meles meles)

    Article • Tuberculosis, May 2008, Elsevier

    Dr Mark Andrew Chambers

  54. Antigen specific immunological responses of badgers (Meles meles) experimentally infected with Mycobacterium bovis

    Article • Veterinary Immunology and Immunopathology, March 2008, Elsevier

    Dr Mark Andrew Chambers

  55. Validation of the BrockTB Stat-Pak Assay for Detection of Tuberculosis in Eurasian Badgers (Meles meles) and Influence of Disease Severity on Diagnostic Accuracy

    Article • Journal of Clinical Microbiology, February 2008, ASM Journals

    Dr Mark Andrew Chambers

  56. Evidence for enhanced central memory priming by live Mycobacterium bovis BCG vaccine in comparison with killed BCG formulations

    Article • Vaccine, January 2008, Elsevier

    Dr Mark Andrew Chambers

  57. Development and Evaluation of a Test for Tuberculosis in Live European Badgers (Meles meles) Based on Measurement of Gamma Interferon mRNA by Real-Time PCR

    Article • Journal of Clinical Microbiology, May 2007, ASM Journals

    Dr Mark Andrew Chambers

  58. The safety and immunogenicity of Bacillus Calmette-Guérin (BCG) vaccine in European badgers (Meles meles)

    Article • Veterinary Immunology and Immunopathology, July 2006, Elsevier

    Dr Mark Andrew Chambers

  59. Progress in the development of vaccines and diagnostic reagents to control tuberculosis in cattle

    Article • The Veterinary Journal, March 2006, Elsevier

    Dr Mark Andrew Chambers

  60. Histopathogenesis of experimental Mycobacterium bovis infection in mice

    Article • Research in Veterinary Science, February 2006, Elsevier

    Dr Mark Andrew Chambers

  61. Protective efficacy induced by Mycobacterium bovis bacille Calmette-Guèrin can be augmented in an antigen independent manner by use of non-coding plasmid DNA

    Article • Vaccine, January 2006, Elsevier

    Dr Mark Andrew Chambers

  62. Frequency of IFN-γ producing cells correlates with adjuvant enhancement of bacille Calmette-Guèrin induced protection against Mycobacterium bovis

    Article • Vaccine, December 2005, Elsevier

    Dr Mark Andrew Chambers

  63. Protective immunity against Mycobacterium bovis induced by vaccination with Rv3109c—a member of the esat-6 gene family

    Article • Vaccine, April 2005, Elsevier

    Dr Mark Andrew Chambers

  64. Use of an Electronic Nose To Diagnose Mycobacterium bovis Infection in Badgers and Cattle

    Article • Journal of Clinical Microbiology, April 2005, ASM Journals

    Dr Mark Andrew Chambers

  65. Nasal boost with adjuvanted heat-killed BCG or arabinomannan–protein conjugate improves primary BCG-induced protection in C57BL/6 mice

    Article • Tuberculosis, January 2005, Elsevier

    Dr Mark Andrew Chambers

  66. RNA Encoding the MPT83 Antigen Induces Protective Immune Responses against Mycobacterium tuberculosis Infection

    Article • Infection and Immunity, November 2004, ASM Journals

    Dr Mark Andrew Chambers

  67. Cloning and sequencing of badger (Meles meles) interferon γ and its detection in badger lymphocytes

    Article • Veterinary Immunology and Immunopathology, September 2004, Elsevier

    Dr Mark Andrew Chambers

  68. Antibody bound to the surface antigen MPB83 ofMycobacterium bovisenhances survival against high dose and low dose challenge

    Article • FEMS Immunology & Medical Microbiology, June 2004, Oxford University Press (OUP)

    Dr Mark Andrew Chambers

  69. A single dose of killed Mycobacterium bovis BCG in a novel class of adjuvant (Novasome™) protects guinea pigs from lethal tuberculosis

    Article • Vaccine, February 2004, Elsevier

    Dr Mark Andrew Chambers

  70. Improved serodetection of Mycobacterium bovis infection in badgers (Meles meles) using multiantigen test formats

    Article • Diagnostic Microbiology and Infectious Disease, July 2003, Elsevier

    Dr Mark Andrew Chambers

  71. Evaluation of adjuvants for protein vaccines against tuberculosis in guinea pigs

    Article • Vaccine, February 2003, Elsevier

    Dr Mark Andrew Chambers

  72. Correlation of ESAT-6-Specific Gamma Interferon Production with Pathology in Cattle following Mycobacterium bovis BCG Vaccination against Experimental Bovine Tuberculosis

    Article • Infection and Immunity, June 2002, ASM Journals

    Dr Mark Andrew Chambers

  73. Immunohistochemical Characterization of Tuberculous and Non-tuberculous Lesionsin Naturally Infected European Badgers (Meles meles)

    Article • Journal of Comparative Pathology, May 2002, Elsevier

    Dr Mark Andrew Chambers

  74. Simple objective measurement of the cutaneous delayed-type hypersensitivity reaction to tuberculin using spectrophotometry

    Article • Skin Research and Technology, May 2002, Wiley

    Dr Mark Andrew Chambers

  75. Value of existing serological tests for identifying badgers that shed Mycobacterium bovis

    Article • Veterinary Microbiology, May 2002, Elsevier

    Dr Mark Andrew Chambers

  76. Vaccination of Guinea Pigs with DNA Encoding the Mycobacterial Antigen MPB83 Influences Pulmonary Pathology but Not Hematogenous Spread following Aerogenic Infection with Mycobacterium bovis

    Article • Infection and Immunity, April 2002, ASM Journals

    Dr Mark Andrew Chambers

  77. Functional genomics reveals the sole sulphate transporter of theMycobacterium tuberculosiscomplex and its relevance to the acquisition of sulphurin vivo

    Article • Molecular Microbiology, February 2002, Wiley

    Dr Mark Andrew Chambers

  78. A DNA vaccine encoding MPB 83 from Mycobacterium bovis reduces M bovis dissemination to the kidneys of mice and is expressed in primary cell cultures of the European badger (Meles meles)

    Article • Research in Veterinary Science, October 2001, Elsevier

    Dr Mark Andrew Chambers

  79. A guinea pig model of low-dose Mycobacterium bovis aerogenic infection

    Article • Veterinary Microbiology, June 2001, Elsevier

    Dr Mark Andrew Chambers

  80. Immunological responses of Eurasian badgers (Meles meles) vaccinated with Mycobacterium bovis BCG (bacillus calmette guerin)

    Article • Veterinary Immunology and Immunopathology, May 2001, Elsevier

    Dr Mark Andrew Chambers

  81. Effective DNA vaccination of cattle with the mycobacterial antigens MPB83 and MPB70 does not compromise the specificity of the comparative intradermal tuberculin skin test

    Article • Vaccine, December 2000, Elsevier

    Dr Mark Andrew Chambers

  82. Identification of a Mycobacterium bovisBCG Auxotrophic Mutant That Protects Guinea Pigs against M. bovis and Hematogenous Spread of Mycobacterium tuberculosis without Sensitization to Tuberculin

    Article • Infection and Immunity, December 2000, ASM Journals

    Dr Mark Andrew Chambers

  83. Comparison of the Protective Efficacy of Bacille Calmette-Guérin Vaccination against Aerosol Challenge with Mycobacterium tuberculosis and Mycobacterium bovis

    Article • Clinical Infectious Diseases, June 2000, Oxford University Press (OUP)

    Dr Mark Andrew Chambers

  84. Vaccination of Mice and Cattle with Plasmid DNA Encoding the Mycobacterium bovis Antigen MPB83

    Article • Clinical Infectious Diseases, June 2000, Oxford University Press (OUP)

    Dr Mark Andrew Chambers

  85. Immunological approaches to the control of tuberculosis in wildlife reservoirs

    Article • Veterinary Immunology and Immunopathology, April 2000, Elsevier

    Dr Mark Andrew Chambers

  86. A lymphocyte transformation assay for the detection of Mycobacterium bovis infection in the Eurasian Badger (Meles meles)

    Article • Veterinary Immunology and Immunopathology, September 1999, Elsevier

    Dr Mark Andrew Chambers

  87. Tuberculosis in badgers (iMeles meles/i).

    Article • CABI Publishing

    Dr Mark Andrew Chambers

  88. Options for the Control of Disease 1: Targeting the Infectious or Parasitic Agent

    Article • Springer Science + Business Media

    Dr Mark Andrew Chambers