Contact

All Stories

  1. Pharmacogenetics-guided dalcetrapib therapy after an acute coronary syndrome

    Article • European Heart Journal, November 2022, Oxford University Press (OUP)

    Marie-Pierre Dubé

  2. Including diverse and admixed populations in genetic epidemiology research

    Article • Genetic Epidemiology, July 2022, Wiley

    Marie-Pierre Dubé

  3. An association study of ABCG2 rs2231142 on the concentrations of allopurinol and its metabolites

    Article • Clinical and Translational Science, June 2022, Wiley

    Marie-Pierre Dubé

  4. Predictive risk factors for hospitalization and response to colchicine in patients with COVID-19

    Article • International Journal of Infectious Diseases, March 2022, Elsevier

    Marie-Pierre Dubé

  5. Leveraging large observational studies to discover genetic determinants of drug concentrations: A proof‐of‐concept study

    Article • Clinical and Translational Science, February 2022, Wiley

    Marie-Pierre Dubé

  6. Gender matters in heart attack prevention: higher femininity linked to angina diagnosis in men

    Article • Scientific Reports, February 2022, Springer Science + Business Media

    Marie-Pierre Dubé

  7. Comparative Effectiveness and Safety of Low-Dose Oral Anticoagulants in Patients With Atrial Fibrillation

    Article • Frontiers in Pharmacology, January 2022, Frontiers

    Marie-Pierre Dubé

  8. A sex-specific evolutionary interaction between ADCY9 and CETP

    Article • eLife, October 2021, eLife

    Marie-Pierre Dubé

  9. Pharmacogenomic study of heart failure and candesartan response from the CHARM programme

    Article • September 2021, Cold Spring Harbor Laboratory Press

    Marie-Pierre Dubé

  10. The genomics of heart failure: design and rationale of the HERMES consortium

    Article • ESC Heart Failure, September 2021, Wiley

    Professor John GF Cleland, Marie-Pierre Dubé

  11. Multitrait GWAS to connect disease variants and biological mechanisms

    Article • PLoS Genetics, August 2021, PLOS

    Marie-Pierre Dubé

  12. Colchicine for community-treated patients with COVID-19 (COLCORONA): a phase 3, randomised, double-blinded, adaptive, placebo-controlled, multicentre trial

    Article • The Lancet Respiratory Medicine, August 2021, Elsevier

    Marie-Pierre Dubé

  13. Genetics of symptom remission in outpatients with COVID-19

    Article • Scientific Reports, May 2021, Springer Science + Business Media

    Marie-Pierre Dubé

  14. A sex-specific evolutionary interaction betweenADCY9andCETP

    Article • May 2021, Cold Spring Harbor Laboratory Press

    Marie-Pierre Dubé

  15. Colchicine for Secondary Prevention of Cardiovascular Disease: A Systematic Review and Meta-analysis of Randomized Controlled Trials

    Article • Canadian Journal of Cardiology, May 2021, Elsevier

    Marie-Pierre Dubé

  16. Pharmacogenomics of the Efficacy and Safety of Colchicine in COLCOT

    Article • Circulation Genomic and Precision Medicine, April 2021, Wolters Kluwer Health

    Marie-Pierre Dubé

  17. Role of Adenylate Cyclase 9 in the Pharmacogenomic Response to Dalcetrapib

    Article • Circulation Genomic and Precision Medicine, April 2021, Wolters Kluwer Health

    Marie-Pierre Dubé

  18. Genetically determined NLRP3 inflammasome activation associates with systemic inflammation and cardiovascular mortality

    Article • European Heart Journal, March 2021, Oxford University Press (OUP)

    Marie-Pierre Dubé

  19. ExPheWas: a browser for gene-based pheWAS associations

    Article • March 2021, Cold Spring Harbor Laboratory Press

    Marie-Pierre Dubé

  20. Genetics of symptom remission in outpatients with COVID-19

    Article • March 2021, Cold Spring Harbor Laboratory Press

    Marie-Pierre Dubé

  21. Genetic meta-analysis of cancer diagnosis following statin use identifies new associations and implicates human leukocyte antigen (HLA) in women

    Article • The Pharmacogenomics Journal, March 2021, Springer Science + Business Media

    Marie-Pierre Dubé

  22. Comparative effectiveness and safety of high‐dose rivaroxaban and apixaban for atrial fibrillation: A propensity score‐matched cohort study

    Article • Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy, February 2021, Wiley

    Marie-Pierre Dubé

  23. Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect

    Article • Nature Genetics, January 2021, Springer Science + Business Media

    Marie-Pierre Dubé

  24. The associations of hostility and defensiveness with telomere length are influenced by sex and health status

    Article • Biology of Sex Differences, January 2021, Springer Science + Business Media

    Marie-Pierre Dubé

  25. A genetic association study of heart failure: more evidence for the role of BAG3 in idiopathic dilated cardiomyopathy

    Article • ESC Heart Failure, September 2020, Wiley

    Marie-Pierre Dubé

  26. Time-to-treatment initiation of colchicine and cardiovascular outcomes after myocardial infarction in the Colchicine Cardiovascular Outcomes Trial (COLCOT)

    Article • European Heart Journal, August 2020, Oxford University Press (OUP)

    Marie-Pierre Dubé

  27. Population Pharmacokinetics of Candesartan in Patients with Chronic Heart Failure

    Article • Clinical and Translational Science, August 2020, Wiley

    Marie-Pierre Dubé

  28. Statin Initiation: Guideline Concordance and Characteristics of New Users in Quebec, Canada

    Article • Journal of Population Therapeutics and Clinical Pharmacology, August 2020, Codon Publications

    Marie-Pierre Dubé

  29. A genetic model of ivabradine recapitulates results from randomized clinical trials

    Article • PLoS ONE, July 2020, PLOS

    Marie-Pierre Dubé

  30. Multitrait genetic-phenotype associations to connect disease variants and biological mechanisms

    Article • June 2020, Cold Spring Harbor Laboratory Press

    Marie-Pierre Dubé

  31. High-sensitivity C-reactive protein is associated with clonal hematopoiesis of indeterminate potential

    Article • Blood Advances, June 2020, American Society of Hematology

    Marie-Pierre Dubé

  32. Cost-effectiveness of low-dose colchicine after myocardial infarction in the Colchicine Cardiovascular Outcomes Trial (COLCOT)

    Article • European Heart Journal - Quality of Care and Clinical Outcomes, May 2020, Oxford University Press (OUP)

    Marie-Pierre Dubé

  33. CYP2D6 polymorphism and its impact on the clinical response to metoprolol: A systematic review and meta‐analysis

    Article • British Journal of Clinical Pharmacology, April 2020, Wiley

    Marie-Pierre Dubé

  34. Heritability of 596 lipid species and genetic correlation with cardiovascular traits in the Busselton Family Heart Study

    Article • Journal of Lipid Research, April 2020, Elsevier

    Marie-Pierre Dubé

  35. Spironolactone metabolite concentrations in decompensated heart failure: insights from the ATHENA‐HF trial

    Article • European Journal of Heart Failure, April 2020, Wiley

    Marie-Pierre Dubé

  36. Study design of Dal-GenE, a pharmacogenetic trial targeting reduction of cardiovascular events with dalcetrapib

    Article • American Heart Journal, April 2020, Elsevier

    Marie-Pierre Dubé

  37. Efficacy and Safety of Low-Dose Colchicine after Myocardial Infarction

    Article • New England Journal of Medicine, December 2019, New England Journal of Medicine (NEJM/MMS)

    Marie-Pierre Dubé

  38. Oral Anticoagulant Prescription Trends, Profile Use, and Determinants of Adherence in Patients with Atrial Fibrillation

    Article • Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy, December 2019, Wiley

    Marie-Pierre Dubé

  39. Inherited Chromosomally Integrated Human Herpesvirus 6 Demonstrates Tissue-Specific RNA Expression In Vivo That Correlates with an Increased Antibody Immune Response

    Article • Journal of Virology, December 2019, ASM Journals

    Marie-Pierre Dubé

  40. Meta-analysis of Randomized Controlled Trials Assessing the Impact of Proprotein Convertase Subtilisin/Kexin Type 9 Antibodies on Mortality and Cardiovascular Outcomes

    Article • The American Journal of Cardiology, December 2019, Elsevier

    Marie-Pierre Dubé

  41. rs73185306 C/T Is Not a Predisposing Risk Factor for Inherited Chromosomally Integrated Human Herpesvirus 6A/B

    Article • The Journal of Infectious Diseases, October 2019, Oxford University Press (OUP)

    Marie-Pierre Dubé

  42. Inherited chromosomally integrated HHV-6 demonstrates tissue-specific RNA expressionin vivothat correlates with increased antibody immune response

    Article • August 2019, Cold Spring Harbor Laboratory Press

    Marie-Pierre Dubé

  43. Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

    Article • Nature Genetics, June 2019, Springer Science + Business Media

    Marie-Pierre Dubé

  44. Validation of Genome-Wide Polygenic Risk Scores for Coronary Artery Disease in French Canadians

    Article • Circulation Genomic and Precision Medicine, June 2019, Wolters Kluwer Health

    Marie-Pierre Dubé

  45. Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events

    Article • Circulation Genomic and Precision Medicine, April 2019, Wolters Kluwer Health

    Professor Marek Sanak, Marie-Pierre Dubé

  46. Subsequent Event Risk in Individuals With Established Coronary Heart Disease

    Article • Circulation Genomic and Precision Medicine, April 2019, Wolters Kluwer Health

    Professor Marek Sanak, Marie-Pierre Dubé

  47. Lipoprotein (a), arterial inflammation, and PCSK9 inhibition

    Article • European Heart Journal, March 2019, Oxford University Press (OUP)

    Marie-Pierre Dubé

  48. Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

    Article • Nature Genetics, February 2019, Springer Science + Business Media

    Marie-Pierre Dubé

  49. Validation of genome-wide polygenic risk scores for coronary artery disease in French Canadians

    Article • February 2019, Cold Spring Harbor Laboratory Press

    Marie-Pierre Dubé

  50. Biomarkers of dementia in obstructive sleep apnea

    Article • Sleep Medicine Reviews, December 2018, Elsevier

    Marie-Pierre Dubé

  51. Pharmacogenetic content of commercial genome-wide genotyping arrays

    Article • Pharmacogenomics, October 2018, Future Medicine

    Marie-Pierre Dubé

  52. Randomized Clinical Trial Needed to Confirm Whether Dalcetrapib Improves Outcomes for Specific ADCY9 Genotype

    Article • JAMA Cardiology, September 2018, American Medical Association (AMA)

    Marie-Pierre Dubé

  53. Variants at the APOE/C1/C2/C4 Locus Modulate Cholesterol Efflux Capacity Independently of High‐Density Lipoprotein Cholesterol

    Article • Journal of the American Heart Association, August 2018, Wolters Kluwer Health

    Marie-Pierre Dubé

  54. Lineage restriction analyses in CHIP indicate myeloid bias for TET2 and multipotent stem cell origin for DNMT3A

    Article • Blood, July 2018, American Society of Hematology

    Marie-Pierre Dubé

  55. Protein-Coding Variants Implicate Novel Genes Related to Lipid Homeostasis Contributing to Body Fat Distribution

    Article • June 2018, Cold Spring Harbor Laboratory Press

    Marie-Pierre Dubé

  56. Sex, drugs, and heart failure: a sex-sensitive review of the evidence base behind current heart failure clinical guidelines

    Article • ESC Heart Failure, June 2018, Wiley

    Marie-Pierre Dubé

  57. Rationale, design, and preliminary results of the Quebec Warfarin Cohort Study

    Article • Clinical Cardiology, May 2018, Wiley

    Marie-Pierre Dubé

  58. Pharmacogenomics of blood lipid regulation

    Article • Pharmacogenomics, April 2018, Future Medicine

    Marie-Pierre Dubé

  59. A prospective study of the impact of AGTR1 A1166C on the effects of candesartan in patients with heart failure

    Article • Pharmacogenomics, April 2018, Future Medicine

    Marie-Pierre Dubé

  60. A Discrete Event Simulation Model to Assess the Economic Value of a Hypothetical Pharmacogenomics Test for Statin-Induced Myopathy in Patients Initiating a Statin in Secondary Cardiovascular Prevention

    Article • Molecular Diagnosis & Therapy, April 2018, Springer Science + Business Media

    Marie-Pierre Dubé

  61. Nuclear receptor gene polymorphisms and warfarin dose requirements in the Quebec Warfarin Cohort

    Article • The Pharmacogenomics Journal, January 2018, Springer Science + Business Media

    Marie-Pierre Dubé

  62. Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

    Article • Nature Genetics, December 2017, Springer Science + Business Media

    Professor Trevor A Mori, Giovanni Veronesi, Marie-Pierre Dubé

  63. Polygenic determinants in extremes of high-density lipoprotein cholesterol

    Article • Journal of Lipid Research, November 2017, Elsevier

    Marie-Pierre Dubé

  64. Exome-wide association study of plasma lipids in >300,000 individuals

    Article • Nature Genetics, October 2017, Springer Science + Business Media

    Marie-Pierre Dubé

  65. Precision medicine to change the landscape of cardiovascular drug development

    Article • Expert Review of Precision Medicine and Drug Development, October 2017, Taylor & Francis

    Marie-Pierre Dubé

  66. Impact of Selection Bias on Estimation of Subsequent Event Risk

    Article • Circulation Cardiovascular Genetics, October 2017, Wolters Kluwer Health

    Marie-Pierre Dubé

  67. Identification of the genetic determinants responsible for retinal degeneration in families of Mexican descent

    Article • Ophthalmic Genetics, September 2017, Taylor & Francis

    Marie-Pierre Dubé

  68. Pharmacogenetics of Lipid-Lowering Agents: an Update Review on Genotype-Dependent Effects of HDL-Targetingand Statin Therapies

    Article • Current Atherosclerosis Reports, September 2017, Springer Science + Business Media

    Marie-Pierre Dubé

  69. DNMT3A and TET2 dominate clonal hematopoiesis and demonstrate benign phenotypes and different genetic predispositions

    Article • Blood, August 2017, American Society of Hematology

    Marie-Pierre Dubé

  70. CKing Precision in the Interpretation of Diagnostic Biomarkers

    Article • Circulation Cardiovascular Genetics, August 2017, Wolters Kluwer Health

    Marie-Pierre Dubé

  71. Diagnosis, Prevalence, Awareness, Treatment, Prevention, and Control of Hypertension in Cameroon: Protocol for a Systematic Review and Meta-Analysis of Clinic-Based and Community-Based Studies

    Article • JMIR Research Protocols, May 2017, JMIR Publications Inc.

    Marie-Pierre Dubé

  72. Protein-altering and regulatory genetic variants near GATA4 implicated in bicuspid aortic valve

    Article • Nature Communications, May 2017, Springer Science + Business Media

    Marie-Pierre Dubé

  73. CYP3A4 genotype is associated with sildenafil concentrations in patients with heart failure with preserved ejection fraction

    Article • The Pharmacogenomics Journal, April 2017, Springer Science + Business Media

    Marie-Pierre Dubé

  74. Methylomic changes in individuals with psychosis, prenatally exposed to endocrine disrupting compounds: Lessons from diethylstilbestrol

    Article • PLoS ONE, April 2017, PLOS

    Marie-Pierre Dubé

  75. CETP

    Article • Arteriosclerosis Thrombosis and Vascular Biology, March 2017, Wolters Kluwer Health

    Marie-Pierre Dubé

  76. Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease

    Article • Journal of the American College of Cardiology, February 2017, Elsevier

    Marie-Pierre Dubé

  77. Pharmacogenomic approaches to lipid-regulating trials

    Article • Current Opinion in Lipidology, December 2016, Wolters Kluwer Health

    Marie-Pierre Dubé

  78. Polygenic Versus Monogenic Causes of Hypercholesterolemia Ascertained Clinically

    Article • Arteriosclerosis Thrombosis and Vascular Biology, December 2016, Wolters Kluwer Health

    Marie-Pierre Dubé

  79. Older adults with heart failure treated with carvedilol, bisoprolol, or metoprolol tartrate: risk of mortality

    Article • Pharmacoepidemiology and Drug Safety, November 2016, Wiley

    Marie-Pierre Dubé

  80. Paternal Age Explains a Major Portion of De Novo Germline Mutation Rate Variability in Healthy Individuals

    Article • PLoS ONE, October 2016, PLOS

    Marie-Pierre Dubé

  81. A model to assess the cost–effectiveness of pharmacogenomics tests in chronic heart failure: the case of ivabradine

    Article • Pharmacogenomics, October 2016, Future Medicine

    Marie-Pierre Dubé

  82. Maximal expected benefits from lowering cholesterol in primary prevention for a high-risk population

    Article • Current Medical Research and Opinion, September 2016, Taylor & Francis

    Marie-Pierre Dubé

  83. Meta-analysis of genome-wide association studies of HDL cholesterol response to statins

    Article • Journal of Medical Genetics, September 2016, BMJ

    Marie-Pierre Dubé

  84. genipe: an automated genome-wide imputation pipeline with automatic reporting and statistical tools

    Article • Bioinformatics, August 2016, Oxford University Press (OUP)

    Marie-Pierre Dubé

  85. Genotype-Dependent Effects of Dalcetrapib on Cholesterol Efflux and Inflammation

    Article • Circulation Cardiovascular Genetics, August 2016, Wolters Kluwer Health

    Marie-Pierre Dubé

  86. Whole-genome sequencing in French Canadians from Quebec

    Article • Human Genetics, July 2016, Springer Science + Business Media

    Marie-Pierre Dubé

  87. Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits

    Article • The American Journal of Human Genetics, July 2016, Elsevier

    Marie-Pierre Dubé

  88. Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals

    Article • The American Journal of Human Genetics, July 2016, Elsevier

    Marie-Pierre Dubé

  89. DNA methylation signature of human fetal alcohol spectrum disorder

    Article • Epigenetics & Chromatin, June 2016, Springer Science + Business Media

    Marie-Pierre Dubé

  90. Avoidance of Vitamin K−Rich Foods Is Common among Warfarin Users and Translates into Lower Usual Vitamin K Intakes

    Article • Journal of the Academy of Nutrition and Dietetics, June 2016, Elsevier

    Marie-Pierre Dubé

  91. Pillbox Use and INR Stability in a Prospective Cohort of New Warfarin Users

    Article • Journal of Managed Care & Specialty Pharmacy, June 2016, Academy of Managed Care Pharmacy

    Marie-Pierre Dubé

  92. Methylomic changes during conversion to psychosis

    Article • Molecular Psychiatry, April 2016, Springer Science + Business Media

    Marie-Pierre Dubé

  93. Coding Variation inANGPTL4,LPL,andSVEP1and the Risk of Coronary Disease

    Article • New England Journal of Medicine, March 2016, New England Journal of Medicine (NEJM/MMS)

    Marie-Pierre Dubé

  94. A pharmacogenetic investigation of intravenous furosemide in decompensated heart failure: a meta-analysis of three clinical trials

    Article • The Pharmacogenomics Journal, March 2016, Springer Science + Business Media

    Marie-Pierre Dubé

  95. An expanded pharmacogenomics warfarin dosing table with utility in generalised dosing guidance

    Article • Thrombosis and Haemostasis, March 2016, Thieme Publishing Group

    Marie-Pierre Dubé

  96. Testing the role of predicted gene knockouts in human anthropometric trait variation

    Article • Human Molecular Genetics, February 2016, Oxford University Press (OUP)

    Marie-Pierre Dubé

  97. Resting heart rate as a predictor of aortic valve stenosis progression

    Article • International Journal of Cardiology, February 2016, Elsevier

    Marie-Pierre Dubé

  98. Pharmacogenomics to Revive Drug Development in Cardiovascular Disease

    Article • Cardiovascular Drugs and Therapy, January 2016, Springer Science + Business Media

    Marie-Pierre Dubé

  99. Calcium Signaling Pathway GenesRUNX2andCACNA1CAre Associated With Calcific Aortic Valve DiseaseCLINICAL PERSPECTIVE

    Article • Circulation Cardiovascular Genetics, November 2015, Wolters Kluwer Health

    Dr Sandra Guauque-Olarte, Marie-Pierre Dubé

  100. Will personalized drugs for cardiovascular disease become an option? – Defining ‘Evidence-based personalized medicine’ for its implementation and future use

    Article • Expert Opinion on Pharmacotherapy, September 2015, Informa Healthcare

    Marie-Pierre Dubé

  101. Impact of regular physical activity on weekly warfarin dose requirement

    Article • Journal of Thrombosis and Thrombolysis, August 2015, Springer Science + Business Media

    Marie-Pierre Dubé

  102. Mutation Burden of Rare Variants in Schizophrenia Candidate Genes

    Article • PLoS ONE, June 2015, PLOS

    Marie-Pierre Dubé

  103. Genetic markers associated with cutaneous adverse drug reactions to allopurinol: a systematic review

    Article • Pharmacogenomics, May 2015, Future Medicine

    Marie-Pierre Dubé

  104. Cardiovascular pharmacogenomics; state of current knowledge and implementation in practice

    Article • International Journal of Cardiology, April 2015, Elsevier

    Marie-Pierre Dubé

  105. Pharmacogenomic Determinants of the Cardiovascular Effects of Dalcetrapib

    Article • Circulation Cardiovascular Genetics, April 2015, Wolters Kluwer Health

    Marie-Pierre Dubé

  106. Comparison of Sequencing Based CNV Discovery Methods Using Monozygotic Twin Quartets

    Article • PLoS ONE, March 2015, PLOS

    Marie-Pierre Dubé

  107. CKM and LILRB5 Are Associated With Serum Levels of Creatine Kinase

    Article • Circulation Cardiovascular Genetics, December 2014, Wolters Kluwer Health

    Marie-Pierre Dubé

  108. Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins

    Article • Nature Communications, October 2014, Springer Science + Business Media

    Professor Janusz Antoni Jankowski, Marie-Pierre Dubé

  109. Genetic Markers of Cisplatin-Induced Hearing Loss in Children

    Article • Clinical Pharmacology & Therapeutics, September 2014, Springer Science + Business Media

    Marie-Pierre Dubé

  110. Modifiers of (CAG)n instability in Machado–Joseph disease (MJD/SCA3) transmissions: an association study with DNA replication, repair and recombination genes

    Article • Human Genetics, July 2014, Springer Science + Business Media

    Jorge Sequeiros, Marie-Pierre Dubé

  111. Development of a broad-based ADME panel for use in pharmacogenomic studies

    Article • Pharmacogenomics, July 2014, Future Medicine

    Marie-Pierre Dubé

  112. Lipoprotein(a) Levels, Genotype, and Incident Aortic Valve Stenosis

    Article • Circulation Cardiovascular Genetics, June 2014, Wolters Kluwer Health

    Marie-Pierre Dubé

  113. Novel presenilin mutations within Moroccan patients with Early-Onset Alzheimer’s Disease

    Article • Neuroscience, June 2014, Elsevier

    Marie-Pierre Dubé

  114. Rare and low-frequency coding variants in CXCR2 and other genes are associated with hematological traits

    Article • Nature Genetics, April 2014, Springer Science + Business Media

    Marie-Pierre Dubé

  115. Novel Mutations in the Amyloid Precursor Protein Gene within Moroccan Patients with Alzheimer's Disease

    Article • Journal of Molecular Neuroscience, March 2014, Springer Science + Business Media

    Marie-Pierre Dubé

  116. Comparison of genotype clustering tools with rare variants

    Article • BMC Bioinformatics, February 2014, Springer Science + Business Media

    Marie-Pierre Dubé

  117. Cuckoo search epistasis: a new method for exploring significant genetic interactions

    Article • Heredity, February 2014, Springer Science + Business Media

    Marie-Pierre Dubé

  118. Validation of patient-reported warfarin dose in a prospective incident cohort study

    Article • Pharmacoepidemiology and Drug Safety, January 2014, Wiley

    Marie-Pierre Dubé

  119. Evaluation of Links Between High-Density Lipoprotein Genetics, Functionality, and Aortic Valve Stenosis Risk in Humans

    Article • Arteriosclerosis Thrombosis and Vascular Biology, December 2013, Wolters Kluwer Health

    Dr Sandra Guauque-Olarte, Marie-Pierre Dubé

  120. Role of TPMT and COMT genetic variation in cisplatin-induced ototoxicity

    Article • Clinical Pharmacology & Therapeutics, November 2013, Springer Science + Business Media

    Marie-Pierre Dubé

  121. pyGenClean: efficient tool for genetic data clean up before association testing

    Article • Bioinformatics, May 2013, Oxford University Press (OUP)

    Marie-Pierre Dubé

  122. Erratum: Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy

    Article • Nature Genetics, April 2013, Springer Science + Business Media

    Marie-Pierre Dubé

  123. Higher frequency of genetic variants conferring increased risk for ADRs for commonly used drugs treating cancer, AIDS and tuberculosis in persons of African descent

    Article • The Pharmacogenomics Journal, April 2013, Springer Science + Business Media

    Marie-Pierre Dubé

  124. Replication of TPMT and ABCC3 Genetic Variants Highly Associated With Cisplatin-Induced Hearing Loss in Children

    Article • Clinical Pharmacology & Therapeutics, April 2013, Springer Science + Business Media

    Marie-Pierre Dubé

  125. The Impact of Partial and Complete Loss-of-Function Mutations in Endothelial Lipase on High-Density Lipoprotein Levels and Functionality in Humans

    Article • Circulation Cardiovascular Genetics, February 2013, Wolters Kluwer Health

    Marie-Pierre Dubé

  126. Institutional Profile: The Beaulieu-Saucier Université de Montréal Pharmacogenomics Centre at the Montreal Heart Institute

    Article • Pharmacogenomics, January 2013, Future Medicine

    Marie-Pierre Dubé

  127. SRAP Polymorphisms Associated to Cell Wall Degradability in Lignified Stems of Alfalfa

    Article • BioEnergy Research, December 2012, Springer Science + Business Media

    Marie-Pierre Dubé

  128. Pooled DNA Resequencing of 68 Myocardial Infarction Candidate Genes in French Canadians

    Article • Circulation Cardiovascular Genetics, October 2012, Wolters Kluwer Health

    Marie-Pierre Dubé

  129. Rare Copy Number Variants Contribute to Congenital Left-Sided Heart Disease

    Article • PLoS Genetics, September 2012, PLOS

    Marie-Pierre Dubé

  130. Genetic control of high density lipoprotein-cholesterol in AcB/BcA recombinant congenic strains of mice

    Article • Physiological Genomics, September 2012, American Physiological Society

    Marie-Pierre Dubé

  131. Segregation of LIPG, CETP, and GALNT2 Mutations in Caucasian Families with Extremely High HDL Cholesterol

    Article • PLoS ONE, August 2012, PLOS

    Marie-Pierre Dubé

  132. Assessment of Genetic Variability of Cell Wall Degradability for the Selection of Alfalfa with Improved Saccharification Efficiency

    Article • BioEnergy Research, May 2012, Springer Science + Business Media

    Marie-Pierre Dubé

  133. PRKCB is associated with calcineurin inhibitor-induced renal dysfunction in heart transplant recipients

    Article • Pharmacogenetics and Genomics, May 2012, Wolters Kluwer Health

    Marie-Pierre Dubé

  134. Pharmacogenomic Prediction of Anthracycline-Induced Cardiotoxicity in Children

    Article • Journal of Clinical Oncology, May 2012, American Society of Clinical Oncology (ASCO)

    Marie-Pierre Dubé

  135. Molecular physiology and breeding at the crossroads of cold hardiness improvement

    Article • Physiologia Plantarum, April 2012, Wiley

    Marie-Pierre Dubé

  136. Risk of congenital heart defects is influenced by genetic variation in folate metabolism

    Article • Cardiology in the Young, April 2012, Cambridge University Press

    Marie-Pierre Dubé

  137. Erratum to: Intron-length polymorphism identifies a Y2K4 dehydrin variant linked to superior freezing tolerance in alfalfa

    Article • Theoretical and Applied Genetics, February 2012, Springer Science + Business Media

    Marie-Pierre Dubé

  138. Validation of warfarin pharmacogenetic algorithms in clinical practice

    Article • Pharmacogenomics, January 2012, Future Medicine

    Marie-Pierre Dubé

  139. Intron-length polymorphism identifies a Y2K4 dehydrin variant linked to superior freezing tolerance in alfalfa

    Article • Theoretical and Applied Genetics, November 2011, Springer Science + Business Media

    Marie-Pierre Dubé

  140. Design and rationale of a genetic cohort study on congenital cardiac disease: experiences from a multi-institutional platform in Quebec

    Article • Cardiology in the Young, July 2011, Cambridge University Press

    Marie-Pierre Dubé

  141. Predicting Statin Induced Muscle Toxicity

    Article • Journal of Clinical Lipidology, May 2011, Elsevier

    Marie-Pierre Dubé

  142. Fetal Alcohol Spectrum Disorders: Gene-Environment Interactions, Predictive Biomarkers, and the Relationship Between Structural Alterations in the Brain and Functional Outcomes

    Article • Seminars in Pediatric Neurology, March 2011, Elsevier

    Marie-Pierre Dubé

  143. Familial ventricular aneurysms and septal defects map to chromosome 10p15

    Article • European Heart Journal, December 2010, European Society of Cardiology

    Marie-Pierre Dubé

  144. Positional cloning of a quantitative trait locus contributing to pain sensitivity: possible mediation by Tyrp1

    Article • Genes Brain & Behavior, November 2010, Wiley

    Marie-Pierre Dubé

  145. A dominant-negative mutation in the TRESK potassium channel is linked to familial migraine with aura

    Article • Nature Reports Stem Cells, September 2010, Nature

    Jorge Sequeiros, Marie-Pierre Dubé

  146. Direct Measure of the De Novo Mutation Rate in Autism and Schizophrenia Cohorts

    Article • The American Journal of Human Genetics, September 2010, Elsevier

    Marie-Pierre Dubé

  147. Partitioning of copy-number genotypes in pedigrees

    Article • BMC Bioinformatics, May 2010, Springer Science + Business Media

    Marie-Pierre Dubé

  148. Family Study of Restless Legs Syndrome in Quebec, Canada

    Article • Archives of Neurology, May 2010, American Medical Association (AMA)

    Marie-Pierre Dubé

  149. Mutations in DCC Cause Congenital Mirror Movements

    Article • Science, April 2010, American Association for the Advancement of Science

    Marie-Pierre Dubé

  150. De novo mutations in the gene encoding the synaptic scaffolding protein SHANK3 in patients ascertained for schizophrenia

    Article • Proceedings of the National Academy of Sciences, April 2010, Proceedings of the National Academy of Sciences

    Marie-Pierre Dubé

  151. Genetic determinants of blood pressure reduction following potassium supplementation: and the candidates are…

    Article • Journal of Hypertension, April 2010, Wolters Kluwer Health

    Marie-Pierre Dubé

  152. Genetics of bronchopulmonary dysplasia in the age of genomics

    Article • Current Opinion in Pediatrics, April 2010, Wolters Kluwer Health

    Marie-Pierre Dubé

  153. Testing for Gene-Gene Interaction with AMMI Models

    Article • Statistical Applications in Genetics and Molecular Biology, January 2010, De Gruyter

    Marie-Pierre Dubé

  154. Novel mutations in the sacsin gene in ataxia patients from Maritime Canada

    Article • Journal of the Neurological Sciences, January 2010, Elsevier

    Marie-Pierre Dubé

  155. Genetic Studies

    Article • November 2009, Springer Science + Business Media

    Marie-Pierre Dubé

  156. Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy

    Article • Nature Genetics, November 2009, Springer Science + Business Media

    Marie-Pierre Dubé

  157. Genetic Modulation of Brugada Syndrome by a Common Polymorphism

    Article • Journal of Cardiovascular Electrophysiology, October 2009, Wiley

    Marie-Pierre Dubé

  158. Application of principal component analysis to pharmacogenomic studies in Canada

    Article • The Pharmacogenomics Journal, August 2009, Springer Science + Business Media

    Marie-Pierre Dubé

  159. Association between cervical and intracranial dimensions and syringomyelia in the cavalier King Charles spaniel

    Article • Journal of Small Animal Practice, August 2009, Wiley

    Marie-Pierre Dubé

  160. Mutation in Pyrroline-5-Carboxylate Reductase 1 Gene in Families with Cutis Laxa Type 2

    Article • The American Journal of Human Genetics, July 2009, Elsevier

    Marie-Pierre Dubé

  161. Application of Homozygosity Haplotype Analysis to Genetic Mapping with High-Density SNP Genotype Data

    Article • PLoS ONE, April 2009, PLOS

    Marie-Pierre Dubé

  162. Genetic predictors of depressive symptoms in cardiac patients

    Article • American Journal of Medical Genetics Part B Neuropsychiatric Genetics, April 2009, Wiley

    Marie-Pierre Dubé

  163. The challenge of detecting epistasis (G×G Interactions): Genetic Analysis Workshop 16

    Article • Genetic Epidemiology, January 2009, Wiley

    Marie-Pierre Dubé

  164. Autosomal-dominant locus for restless legs syndrome in French-Canadians on chromosome 16p12.1

    Article • Movement Disorders, October 2008, Wiley

    Marie-Pierre Dubé

  165. Génome Québec & Montreal Heart Institute Pharmacogenomics Centre: a translational pharmacogenomics platform – from R&D to the clinic

    Article • Pharmacogenomics, October 2008, Future Medicine

    Marie-Pierre Dubé

  166. Mutations in the calcium-related gene IL1RAPL1 are associated with autism

    Article • Human Molecular Genetics, September 2008, Oxford University Press (OUP)

    Marie-Pierre Dubé

  167. A survey of the personalized medicine landscape

    Article • Pharmacogenomics, July 2008, Future Medicine

    Marie-Pierre Dubé

  168. Effects of AGTR1 A1166C Gene Polymorphism in Patients with Heart Failure Treated with Candesartan

    Article • Annals of Pharmacotherapy, May 2008, SAGE Publications

    Marie-Pierre Dubé

  169. Ten renin-angiotensin system-related gene polymorphisms in maximally treated Canadian Caucasian patients with heart failure

    Article • British Journal of Clinical Pharmacology, May 2008, Wiley

    Marie-Pierre Dubé

  170. A novel locus for idiopathic generalized epilepsy in French-Canadian families maps to 10p11

    Article • American Journal of Medical Genetics Part A, March 2008, Wiley

    Marie-Pierre Dubé

  171. No evidence that skewing of X chromosome inactivation patterns is transmitted to offspring in humans

    Article • Journal of Clinical Investigation, January 2008, American Society for Clinical Investigation

    Marie-Pierre Dubé

  172. The Genetics of Congenital Amusia (Tone Deafness): A Family-Aggregation Study

    Article • The American Journal of Human Genetics, September 2007, Elsevier

    Marie-Pierre Dubé

  173. Mutations in the UBIAD1 Gene, Encoding a Potential Prenyltransferase, Are Causal for Schnyder Crystalline Corneal Dystrophy

    Article • PLoS ONE, August 2007, PLOS

    Marie-Pierre Dubé

  174. Syringomyelia in cavalier King Charles spaniels: the relationship between syrinx dimensions and pain

    Article • Journal of Small Animal Practice, August 2007, Wiley

    Marie-Pierre Dubé

  175. Obesity and TCF7L2 variants' additive effect on type 2 diabetes risk in cardiac patients

    Article • Diabetes Care, June 2007, American Diabetes Association

    Marie-Pierre Dubé

  176. Molecular genetic studies of DMT1 on 12q in French‐Canadian restless legs syndrome patients and families

    Article • American Journal of Medical Genetics Part B Neuropsychiatric Genetics, May 2007, Wiley

    Marie-Pierre Dubé

  177. Loss-of-function genetic diseases and the concept of pharmaceutical targets

    Article • Nature Reviews Genetics, May 2007, Springer Science + Business Media

    Marie-Pierre Dubé

  178. Loss-of-function mutations in the Nav1.7 gene underlie congenital indifference to pain in multiple human populations

    Article • Clinical Genetics, March 2007, Wiley

    Marie-Pierre Dubé

  179. Lamin A/C mutations associated with familial and sporadic cases of dilated cardiomyopathy in Koreans

    Article • Experimental & Molecular Medicine, February 2007, Springer Science + Business Media

    Marie-Pierre Dubé

  180. Multistage designs in the genomic era: Providing balance in complex disease studies

    Article • Genetic Epidemiology, January 2007, Wiley

    Marie-Pierre Dubé

  181. A novel autosomal dominant restless legs syndrome locus maps to chromosome 20p13

    Article • Neurology, September 2006, Wolters Kluwer Health

    Marie-Pierre Dubé

  182. Bootstrap Inference with Neural-Network Modeling for Gene-Disease Association Testing

    Article • September 2006, Institute of Electrical & Electronics Engineers (IEEE)

    Marie-Pierre Dubé

  183. A new locus for autosomal dominant intracranial aneurysm, ANIB4, maps to chromosome 5p15.2-14.3

    Article • Journal of Medical Genetics, June 2006, BMJ

    Marie-Pierre Dubé

  184. Human monogenic disorders — a source of novel drug targets

    Article • Nature Reviews Genetics, March 2006, Springer Science + Business Media

    Marie-Pierre Dubé

  185. Common Genetic Vulnerability to Depressive Symptoms and Coronary Artery Disease: A Review and Development of Candidate Genes Related to Inflammation and Serotonin

    Article • Psychosomatic Medicine, March 2006, Wolters Kluwer Health

    Marie-Pierre Dubé

  186. Autism spectrum disorders associated with X chromosome markers in French-Canadian males

    Article • Molecular Psychiatry, November 2005, Springer Science + Business Media

    Marie-Pierre Dubé

  187. A Variant in XPNPEP2 Is Associated with Angioedema Induced by Angiotensin I–Converting Enzyme Inhibitors

    Article • The American Journal of Human Genetics, October 2005, Elsevier

    Marie-Pierre Dubé

  188. Analysis of microsatellite markers and single nucleotide polymorphisms in candidate genes for susceptibility to bipolar affective disorder in the chromosome 12Q24.31 region

    Article • American Journal of Medical Genetics Part B Neuropsychiatric Genetics, March 2005, Wiley

    Marie-Pierre Dubé

  189. Chromosome 11-q24 region in Tourette syndrome: Association and linkage disequilibrium study in the French Canadian population

    Article • American Journal of Medical Genetics Part A, January 2005, Wiley

    Marie-Pierre Dubé

  190. A novel apoA-I mutation (L178P) leads to endothelial dysfunction, increased arterial wall thickness, and premature coronary artery disease

    Article • Journal of the American College of Cardiology, October 2004, Elsevier

    Marie-Pierre Dubé

  191. The 14q restless legs syndrome locus in the French Canadian population

    Article • Annals of Neurology, May 2004, Wiley

    Marie-Pierre Dubé

  192. Identification of a Novel Gene (HSN2) Causing Hereditary Sensory and Autonomic Neuropathy Type II through the Study of Canadian Genetic Isolates

    Article • The American Journal of Human Genetics, May 2004, Elsevier

    Marie-Pierre Dubé

  193. Mutations in HFE2 cause iron overload in chromosome 1q–linked juvenile hemochromatosis

    Article • Nature Genetics, November 2003, Springer Science + Business Media

    Marie-Pierre Dubé

  194. Article • Cancer Causes & Control, January 2003, Springer Science + Business Media

    Marie-Pierre Dubé

  195. AnALS2gene mutation causes hereditary spastic paraplegia in a Pakistani kindred

    Article • Annals of Neurology, December 2002, Wiley

    Marie-Pierre Dubé

  196. Mutant frizzled-4 disrupts retinal angiogenesis in familial exudative vitreoretinopathy

    Article • Nature Genetics, August 2002, Springer Science + Business Media

    Marie-Pierre Dubé

  197. Fine mapping the candidate region for peripheral neuropathy with or without agenesis of the corpus callosum in the French Canadian population

    Article • European Journal of Human Genetics, July 2002, Springer Science + Business Media

    Marie-Pierre Dubé

  198. Progesterone receptor variant increases ovarian cancer risk in BRCA1 and BRCA2 mutation carriers who were never exposed to oral contraceptives

    Article • Pharmacogenetics, October 2001, Wolters Kluwer Health

    Marie-Pierre Dubé

  199. Clouston hidrotic ectodermal dysplasia (HED): genetic homogeneity, presence of a founder effect in the French Canadian population and fine genetic mapping

    Article • European Journal of Human Genetics, May 2000, Springer Science + Business Media

    Marie-Pierre Dubé

  200. Genomic structure of the human GT334 (EHOC-1) gene mapping to 21q22.3

    Article • Gene, October 1997, Elsevier

    Marie-Pierre Dubé