All Stories

  1. Hepatitis C Virus-Specific T Cell Receptor mRNA-Engineered Human T Cells: Impact of Antigen Specificity on Functional Properties

    Article • Journal of Virology, February 2017, ASM Journals

    Associate Professor Margaret Chen

  2. Ameloblastoma RNA profiling uncovers a distinct non-coding RNA signature

    Article • Oncotarget, January 2017, Impact Journals, LLC

    Associate Professor Margaret Chen

  3. Functional differences in hepatitis C virus nonstructural (NS) 3/4A- and 5A-specific T cell responses

    Article • Scientific Reports, May 2016, Nature

    Associate Professor Margaret Chen

  4. Electroporation for therapeutic DNA vaccination in patients

    Article • Medical Microbiology and Immunology, December 2014, Springer Science + Business Media

    Associate Professor Margaret Chen

  5. A randomized controlled trial: the efficacy of eluoride rinse combined with calcium pre-rinse to increase overnight salivary fluoride

    Article • Acta Odontologica Scandinavica, December 2013, Informa Healthcare

    Associate Professor Margaret Chen

  6. Functional Attributes of Responding T Cells in HCV Infection: The Recent Advances in Engineering Functional Antiviral T Cells

    Article • Archivum Immunologiae et Therapiae Experimentalis, August 2013, Springer Science + Business Media

    Associate Professor Margaret Chen

  7. Containing “The Great Houdini” of viruses: Combining direct acting antivirals with the host immune response for the treatment of chronic hepatitis C

    Article • Drug Resistance Updates, July 2013, Elsevier

    Associate Professor Margaret Chen

  8. TCR-Redirected Human T Cells Inhibit Hepatitis C Virus Replication: Hepatotoxic Potential Is Linked to Antigen Specificity and Functional Avidity

    Article • The Journal of Immunology, September 2012, The American Association of Immunologists

    Associate Professor Margaret Chen, Ralf Bartenschlager

  9. Signaling pathways involved in the regulation of TNFα-induced toll-like receptor 2 expression in human gingival fibroblasts

    Article • Cytokine, March 2012, Elsevier

    Associate Professor Margaret Chen

  10. Generation of T-cell receptors targeting a genetically stable and immunodominant cytotoxic T-lymphocyte epitope within hepatitis C virus non-structural protein 3

    Article • Journal of General Virology, November 2011, Society for General Microbiology

    Associate Professor Margaret Chen, Ralf Bartenschlager

  11. Heterologous T Cells Can Help Restore Function in Dysfunctional Hepatitis C Virus Nonstructural 3/4A-Specific T Cells during Therapeutic Vaccination

    Article • The Journal of Immunology, March 2011, The American Association of Immunologists

    Associate Professor Margaret Chen

  12. 1207 HETEROLOGOUS T CELLS CAN HELP RESTORE FUNCTION IN DYSFUNCTIONAL HEPATITIS C VIRUS SPECIFIC T CELLS DURING THERAPEUTIC VACCINATION

    Article • Journal of Hepatology, March 2011, Elsevier

    Associate Professor Margaret Chen

  13. Role of innate signalling pathways in the immunogenicity of alphaviral replicon-based vaccines

    Article • Virology Journal, January 2011, Springer Science + Business Media

    Professor Peter Liljeström, Associate Professor Margaret Chen

  14. Electroporation: A promising method for the nonviral delivery of DNA vaccines in humans?

    Article • Drug News & Perspectives, January 2010, Prous Science

    Associate Professor Margaret Chen

  15. Molecular basis for antibody cross-reactivity between the hepatitis C virus core protein and the host-derived GOR protein

    Article • Clinical & Experimental Immunology, June 2008, Wiley

    Associate Professor Margaret Chen

  16. MyD88 Expression Is Required for Efficient Cross-Presentation of Viral Antigens from Infected Cells

    Article • Journal of Virology, March 2005, ASM Journals

    Professor Peter Liljeström, Associate Professor Margaret Chen

  17. Immune Tolerance Split between Hepatitis B Virus Precore and Core Proteins

    Article • Journal of Virology, March 2005, ASM Journals

    Associate Professor Margaret Chen

  18. A function of the hepatitis B virus precore protein is to regulate the immune response to the core antigen

    Article • Proceedings of the National Academy of Sciences, October 2004, Proceedings of the National Academy of Sciences

    Associate Professor Margaret Chen

  19. Vaccination with Recombinant Alphavirus or Immune-Stimulating Complex Antigen Against Respiratory Syncytial Virus

    Article • The Journal of Immunology, September 2002, The American Association of Immunologists

    Professor Peter Liljeström, Associate Professor Margaret Chen

  20. Modeling the T-helper cell response in acute and chronic hepatitis B virus infection using T-cell receptor transgenic mice

    Article • Antiviral Research, November 2001, Elsevier

    Associate Professor Margaret Chen

  21. Humoral and CD4+ T helper (Th) cell responses to the hepatitis C virus non-structural 3 (NS3) protein: NS3 primes Th1-like responses more effectively as a DNA-based immunogen than as a recombinant protein

    Article • Journal of General Virology, June 2001, Society for General Microbiology

    Associate Professor Margaret Chen

  22. Nondeletional T-Cell Receptor Transgenic Mice: Model for the CD4+ T-Cell Repertoire in Chronic Hepatitis B Virus Infection

    Article • Journal of Virology, August 2000, ASM Journals

    Associate Professor Margaret Chen

  23. Characterization of a Monoclonal Antibody and Its Single-Chain Antibody Fragment Recognizing the Nucleoside Triphosphatase/Helicase Domain of the Hepatitis C Virus Nonstructural 3 Protein

    Article • Clinical and Diagnostic Laboratory Immunology, January 2000, ASM Journals

    Associate Professor Margaret Chen

  24. Changing Profile of HIV-1 Serotypes in Iceland During 1989-96

    Article • Scandinavian Journal of Infectious Diseases, January 2000, Taylor & Francis

    Associate Professor Margaret Chen

  25. Limited humoral immunity in hepatitis C virus infection

    Article • Gastroenterology, January 1999, Elsevier

    Associate Professor Margaret Chen

  26. Human and murine antibody recognition is focused on the ATPase/Helicase, but not the protease domain of the hepatitis C virus nonstructural 3 protein

    Article • Hepatology, July 1998, Wiley

    Associate Professor Margaret Chen

  27. Genetic Evidence for Mother‐to‐Infant Transmission of Hepatitis G Virus

    Article • The Journal of Infectious Diseases, July 1997, Oxford University Press (OUP)

    Associate Professor Margaret Chen

  28. GENETIC EVIDENCE FOR MOTHER-TO-INFANT TRANSMISSION OF HEPATITIS G (GB-C) VIRUS

    Article • Journal of Pediatric Gastroenterology and Nutrition, April 1997, Wolters Kluwer Health

    Associate Professor Margaret Chen

  29. Immunogenicity and antigenicity of the ATPase/helicase domain of the hepatitis C virus non-structural 3 protein

    Article • Journal of General Virology, November 1996, Society for General Microbiology

    Associate Professor Margaret Chen

  30. Distinguishing Acute from Symptomatic Chronic Hepatitis C Virus (HCV) Infection by Site-Directed Serology of the HCV Structural Proteins

    Article • The Journal of Infectious Diseases, May 1995, Oxford University Press (OUP)

    Associate Professor Margaret Chen

  31. Detection of hepatitis C virus RNA in the cell fraction of saliva before and after oral surgery

    Article • Journal of Medical Virology, February 1995, Wiley

    Associate Professor Margaret Chen

  32. Evaluation of a multiple peptide assay for typing of antibodies to the hepatitis C virus: Relation to genomic typing by the polymerase chain reaction

    Article • Journal of Medical Virology, January 1995, Wiley

    Associate Professor Margaret Chen