All Stories

  1. Targeting deoxyhypusine hydroxylase activity impairs cap-independent translation initiation driven by the 5'untranslated region of the HIV-1, HTLV-1, and MMTV mRNAs

    Article • Antiviral Research, October 2016, Elsevier

    Dr Marcelo Lopez-Lastra

  2. Structural domains within the HIV-1 mRNA and the ribosomal protein S25 influence cap-independent translation initiation

    Article • FEBS Journal, June 2016, Wiley

    Dr Marcelo Lopez-Lastra

  3. Polypyrimidine tract-binding protein binds to the 5′ untranslated region of the mouse mammary tumor virus mRNA and stimulates cap-independent translation initiation

    Article • FEBS Journal, April 2016, Wiley

    Dr Marcelo Lopez-Lastra

  4. Urinary leukotriene and Bcl I polymorphism of glucocorticoid receptor gene in preschoolers with recurrent wheezing and high risk of asthma

    Article • Allergologia et Immunopathologia, January 2016, Elsevier

    Dr Marcelo Lopez-Lastra, Dr Jose A. Castro-Rodriguez

  5. LOOP IIId of the HCV IRES is essential for the structural rearrangement of the 40S-HCV IRES complex

    Article • Nucleic Acids Research, November 2015, Oxford University Press (OUP)

    Dr Marcelo Lopez-Lastra

  6. Association of Single-Nucleotide Polymorphisms in IL28B, but Not TNF-α, With Severity of Disease Caused by Andes Virus

    Article • Clinical Infectious Diseases, September 2015, Oxford University Press (OUP)

    Dr Marcelo Lopez-Lastra, Natalia Echeverría

  7. Vitamin D levels and vitamin D receptor gene polymorphisms in asthmatic children: a case-control study

    Article • Pediatric Allergy and Immunology, June 2015, Wiley

    Dr Jose A. Castro-Rodriguez, Dr Marcelo Lopez-Lastra

  8. P0882 : Pilot study of ezetimibe for chronic hepatitis C infection: Effect of treatment in plasma, bile and stool viral load in humans

    Article • Journal of Hepatology, April 2015, Elsevier

    Dr Marcelo Lopez-Lastra

  9. Translation initiation of the HIV-1 mRNA

    Article • Translation, October 2014, Taylor & Francis

    Dr Marcelo Lopez-Lastra

  10. The 5' Untranslated Region of the Human T-Cell Lymphotropic Virus Type 1 mRNA Enables Cap-Independent Translation Initiation

    Article • Journal of Virology, March 2014, ASM Journals

    Dr Marcelo Lopez-Lastra

  11. Translation initiation of the HIV-1 mRNA

    Article • Translation, January 2014, Taylor & Francis

    Dr Marcelo Lopez-Lastra

  12. P16: Analysis of genetic determinants associated with therapy response against hepatitis C virus: first study of IL28B polymorphisms in Uruguayan patients

    Article • Journal of Viral Hepatitis, September 2013, Wiley

    Dr Marcelo Lopez-Lastra

  13. IL28B Polymorphisms Among Latin American HCV Patients

    Article • Current Hepatology Reports, August 2013, Springer Science + Business Media

    Dr Marcelo Lopez-Lastra

  14. Dual Mechanisms of Translation Initiation of the Full-Length HIV-1 mRNA Contribute to Gag Synthesis

    Article • PLoS ONE, July 2013, PLOS

    Dr Marcelo Lopez-Lastra

  15. Genetic variations in host IL28B links to the detection of peripheral blood mononuclear cells-associated hepatitis C virus RNA in chronically infected patients

    Article • Journal of Viral Hepatitis, March 2013, Wiley

    Dr Marcelo Lopez-Lastra

  16. A cis-Acting Element Present within the gag Open Reading Frame Negatively Impacts on the Activity of the HIV-1 IRES

    Article • PLoS ONE, February 2013, PLOS

    Dr Marcelo Lopez-Lastra

  17. Translation initiation is driven by different mechanisms on the HIV-1 and HIV-2 genomic RNAs

    Article • Virus Research, February 2013, Elsevier

    Dr Ricardo Soto-Rifo, Dr Marcelo Lopez-Lastra

  18. Functional and Structural Analysis of the Internal Ribosome Entry Site Present in the mRNA of Natural Variants of the HIV-1

    Article • PLoS ONE, April 2012, PLOS

    Dr Marcelo Lopez-Lastra

  19. The Andes Hantavirus NSs Protein Is Expressed from the Viral Small mRNA by a Leaky Scanning Mechanism

    Article • Journal of Virology, December 2011, ASM Journals

    Dr Ricardo Soto-Rifo, Dr Marcelo Lopez-Lastra

  20. Activity of the human immunodeficiency virus type 1 cell cycle-dependent internal ribosomal entry site is modulated by IRES trans-acting factors

    Article • Nucleic Acids Research, April 2011, Oxford University Press (OUP)

    Dr Marcelo Lopez-Lastra

  21. Infection of human monocyte-derived dendritic cells by ANDES Hantavirus enhances pro-inflammatory state, the secretion of active MMP-9 and indirectly enhances endothelial permeability

    Article • Virology Journal, January 2011, Springer Science + Business Media

    Dr Marcelo Lopez-Lastra

  22. The 3′ Untranslated Region of the Andes Hantavirus Small mRNA Functionally Replaces the Poly(A) Tail and Stimulates Cap-Dependent Translation Initiation from the Viral mRNA

    Article • Journal of Virology, July 2010, ASM Journals

    Dr Ricardo Soto-Rifo, Dr Marcelo Lopez-Lastra

  23. Translation initiation of viral mRNAs

    Article • Reviews in Medical Virology, May 2010, Wiley

    Dr Marcelo Lopez-Lastra

  24. The 5'-untranslated region of the mouse mammary tumor virus mRNA exhibits cap-independent translation initiation

    Article • Nucleic Acids Research, November 2009, Oxford University Press (OUP)

    Dr Marcelo Lopez-Lastra

  25. Human Immunodeficiency Virus Type 1 (HIV-1) Induces the Cytoplasmic Retention of Heterogeneous Nuclear Ribonucleoprotein A1 by Disrupting Nuclear Import: IMPLICATIONS FOR HIV-1 GENE EXPRESSION

    Article • Journal of Biological Chemistry, September 2009, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Marcelo Lopez-Lastra

  26. The Elav-like protein HuR exerts translational control of viral internal ribosome entry sites

    Article • Virology, September 2009, Elsevier

    Dr Marcelo Lopez-Lastra

  27. Hepatitis C virusquasispeciesin plasma and peripheral blood mononuclear cells of treatment naïve chronically infected patients

    Article • Journal of Viral Hepatitis, September 2009, Wiley

    Dr Marcelo Lopez-Lastra

  28. Is Single-Strand Conformation Polymorphism Analysis of the Full 5′ Untranslated Region an Adequate Approach To Study Hepatitis C Virus Quasispecies Distribution?

    Article • Journal of Virology, June 2009, ASM Journals

    Dr Marcelo Lopez-Lastra

  29. Andes Virus Antigens Are Shed in Urine of Patients with Acute Hantavirus Cardiopulmonary Syndrome

    Article • Journal of Virology, March 2009, ASM Journals

    Dr Marcelo Lopez-Lastra

  30. Mechanism of HIV-1 Tat RNA translation and its activation by the Tat protein

    Article • Retrovirology, January 2009, Springer Science + Business Media

    Dr Ricardo Soto-Rifo, Dr Marcelo Lopez-Lastra

  31. Analysis of natural variants of the hepatitis C virus internal ribosome entry site reveals that primary sequence plays a key role in cap-independent translation

    Article • Nucleic Acids Research, December 2008, Oxford University Press (OUP)

    Dr Marcelo Lopez-Lastra

  32. Translational control of retroviruses

    Article • Nature Reviews Microbiology, February 2007, Nature

    Dr Marcelo Lopez-Lastra

  33. Hepatitis C en Chile: Magnitud del problema

    Article • Revista médica de Chile, June 2006, SciELO Comision Nacional de Investigacion Cientifica Y Tecnologica (CONICYT)

    Dr Marcelo Lopez-Lastra

  34. Complete Translation of the Hepatitis C Virus Genome In Vitro: Membranes Play a Critical Role in the Maturation of All Virus Proteins except for NS3

    Article • Journal of Virology, June 2005, ASM Journals

    Dr Marcelo Lopez-Lastra

  35. Protein synthesis in eukaryotes: The growing biological relevance of cap-independent translation initiation

    Article • Biological Research, January 2005, SciELO Comision Nacional de Investigacion Cientifica Y Tecnologica (CONICYT)

    Dr Marcelo Lopez-Lastra

  36. The Leader of Human Immunodeficiency Virus Type 1 Genomic RNA Harbors an Internal Ribosome Entry Segment That Is Active during the G2/M Phase of the Cell Cycle

    Article • Journal of Virology, April 2003, ASM Journals

    Dr Marcelo Lopez-Lastra

  37. PKR-Dependent Mechanisms of Gene Expression from a Subgenomic Hepatitis C Virus Clone

    Article • Journal of Virology, November 2002, ASM Journals

    Dr Marcelo Lopez-Lastra

  38. Efficient gene transfer in mouse neural precursors with a bicistronic retroviral vector

    Article • Journal of Neuroscience Research, January 2001, Wiley

    Dr Marcelo Lopez-Lastra

  39. L'initiation de la synthèse des protéines chez les eucaryotes.

    Article • médecine/sciences, January 2000, INIST-CNRS

    Dr Marcelo Lopez-Lastra

  40. Retroviral Vectors for the Expression of Two Genes in Human Multipotent Neural Precursors and Their Differentiated Neuronal and Glial Progeny

    Article • Human Gene Therapy, May 1999, Mary Ann Liebert Inc

    Dr Marcelo Lopez-Lastra

  41. Characterization of an Internal Ribosomal Entry Segment Within the 5′ Leader of Avian Reticuloendotheliosis Virus Type A RNA and Development of Novel MLV-REV-Based Retroviral Vectors

    Article • Human Gene Therapy, November 1997, Mary Ann Liebert Inc

    Dr Marcelo Lopez-Lastra

  42. Determination of Gizzerosine Activity in Fish Meal with a Homologous Radioimmunoassay

    Article • Poultry Science, July 1996, Oxford University Press (OUP)

    Dr Marcelo Lopez-Lastra

  43. Inhibitors of infectious pancreatic necrosis virus (IPNV) replication

    Article • Antiviral Research, March 1996, Elsevier

    Dr Marcelo Lopez-Lastra

  44. Polyacrylamide gel electrophoresis of viral genomic RNA as a diagnostic method for infectious pancreatic necrosis virus detection

    Article • Journal of Virological Methods, December 1994, Elsevier

    Dr Marcelo Lopez-Lastra

  45. A detection method for infectious pancreatic necrosis virus (IPNV) based on reverse transcription (RT)-polymerase chain reaction (PCR)

    Article • Journal of Fish Diseases, May 1994, Wiley

    Dr Marcelo Lopez-Lastra