Contact

All Stories

  1. Functional characterization of 84 PALB2 variants of uncertain significance

    Article • Genetics in Medicine, October 2019, Springer Science + Business Media

    Dr Marcelo A Carvalho

  2. Network of Interactions between ZIKA Virus Non-structural Proteins and Human Host Proteins

    Article • September 2019, MDPI AG

    Dr Marcelo A Carvalho

  3. Impact of amino acid substitutions at secondary structures in the BRCT domains of the tumor suppressor BRCA1: Implications for clinical annotation

    Article • Journal of Biological Chemistry, February 2019, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Marcelo A Carvalho

  4. OUP accepted manuscript

    Article • Nucleic Acids Research, January 2019, Oxford University Press (OUP)

    Dr Marcelo A Carvalho

  5. Modulation of the prostaglandin-endoperoxide synthase 2 gene expression by variant haplotypes: influence of the 3′-untranslated region

    Article • Brazilian Journal of Medical and Biological Research, November 2017, FapUNIFESP (SciELO)

    Dr Marcelo A Carvalho

  6. The Role of PALB2 in the DNA Damage Response and Cancer Predisposition

    Article • International Journal of Molecular Sciences, August 2017, MDPI AG

    Dr Marcelo A Carvalho

  7. Reduced levels of resistance protein ABCB1 associated with worse prognosis in breast cancer patients

    Article • Breast Cancer Targets and Therapy, June 2017, Dove Medical Press

    João Delou , Dr Marcelo A Carvalho

  8. DNA repair genes PAXIP1 and TP53BP1 expression is associated with breast cancer prognosis

    Article • Cancer Biology & Therapy, May 2017, Taylor & Francis

    Dr Marcelo A Carvalho, ALVARO MONTEIRO

  9. BRCA1 recruitment to damaged DNA sites is dependent on CDK9

    Article • Cell Cycle, February 2017, Taylor & Francis

    Dr Marcelo A Carvalho

  10. Synthetic Organotellurium Compounds Sensitize Drug-Resistant Candida albicans Clinical Isolates to Fluconazole

    Article • Antimicrobial Agents and Chemotherapy, November 2016, ASM Journals

    Dr Antonio Ferreira-Pereira, Dr Marcelo A Carvalho

  11. Functional assays provide a robust tool for the clinical annotation of genetic variants of uncertain significance

    Article • npj Genomic Medicine, March 2016, Springer Science + Business Media

    Dr Marcelo A Carvalho

  12. Enhancer scanning to locate regulatory regions in genomic loci

    Article • Nature Protocols, December 2015, Nature

    Dr Marcelo A Carvalho

  13. Abstract 3025: Characterization of CDK9/BRCA1 complex in DNA damage response

    Article • Cancer Research, August 2015, American Association for Cancer Research (AACR)

    Dr Marcelo A Carvalho

  14. BRCA1 Circos: a visualisation resource for functional analysis of missense variants

    Article • Journal of Medical Genetics, February 2015, BMJ

    Dr Randall C Johnson, Dr Marcelo A Carvalho

  15. Galectin-3 Up-Regulation in Hypoxic and Nutrient Deprived Microenvironments Promotes Cell Survival

    Article • PLoS ONE, November 2014, PLOS

    Dr Marcelo A Carvalho

  16. Abstract 480: CDK9 (a novel BRCA1/BARD1 interaction partner) downregulates BRCA1-mediated transcription

    Article • Cancer Research, September 2014, American Association for Cancer Research (AACR)

    Dr Marcelo A Carvalho

  17. Probing Structure-Function Relationships in Missense Variants in the Carboxy-Terminal Region of BRCA1

    Article • PLoS ONE, May 2014, PLOS

    Dr Marcelo A Carvalho

  18. Characterization ofLGALS3(galectin-3) as a player in DNA damage response

    Article • Cancer Biology & Therapy, April 2014, Taylor & Francis

    Dr Marcelo A Carvalho

  19. Epidermal growth factor receptor gene polymorphisms are associated with prognostic features of breast cancer

    Article • BMC Cancer, March 2014, Springer Science + Business Media

    Dr Marcelo A Carvalho

  20. Abstract 632: Characterization of BCCIP as a novel BARD1 interaction partner.

    Article • Cancer Research, April 2013, American Association for Cancer Research (AACR)

    Dr Marcelo A Carvalho

  21. Charting the Landscape of Tandem BRCT Domain-Mediated Protein Interactions

    Article • Science Signaling, September 2012, American Association for the Advancement of Science

    Dr Marcelo A Carvalho

  22. A guide for functional analysis ofBRCA1variants of uncertain significance

    Article • Human Mutation, July 2012, Wiley

    Dr Marcelo A Carvalho

  23. Abstract 2132: Characterization of galectin 3 as a novel BARD1 interaction partner

    Article • Cancer Research, April 2012, American Association for Cancer Research (AACR)

    Dr Marcelo A Carvalho

  24. Aminoglycoside-induced suppression of CYP2C19*3 premature stop codon

    Article • Pharmacogenetics and Genomics, November 2011, Wolters Kluwer Health

    Dr Marcelo A Carvalho

  25. Abstract 3927: Characterization of galectin 3 as a putative BRCA1/BARD1 ubiquitin E3 ligase substrate

    Article • Cancer Research, April 2011, American Association for Cancer Research (AACR)

    Dr Marcelo A Carvalho

  26. Abstract 1117: Characterization of BAT1 (UAP56) interaction with BARD1

    Article • Cancer Research, April 2010, American Association for Cancer Research (AACR)

    Dr Marcelo A Carvalho

  27. Ectopic expression of Histone H2AX mutants reveal a role for its post-translational modifications

    Article • Cancer Biology & Therapy, March 2009, Taylor & Francis

    Dr Marcelo A Carvalho

  28. Analysis of a set of missense, frameshift, and in-frame deletion variants of BRCA1

    Article • Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, January 2009, Elsevier

    Dr Marcelo A Carvalho

  29. Pathogenicity of the BRCA1 missense variant M1775K is determined by the disruption of the BRCT phosphopeptide-binding pocket: a multi-modal approach

    Article • European Journal of Human Genetics, February 2008, Nature

    Dr Marcelo A Carvalho

  30. Correction: Functional analysis of BRCA1 M1628V variant

    Article • Journal of Medical Genetics, May 2007, BMJ

    Dr Marcelo A Carvalho

  31. Determination of Cancer Risk Associated with Germ Line BRCA1 Missense Variants by Functional Analysis

    Article • Cancer Research, February 2007, American Association for Cancer Research (AACR)

    Dr Marcelo A Carvalho

  32. Functional assays for BRCA1 and BRCA2

    Article • The International Journal of Biochemistry & Cell Biology, January 2007, Elsevier

    Dr Marcelo A Carvalho

  33. Functional Impact of Missense Variants in BRCA1 Predicted by Supervised Learning

    Article • PLoS Computational Biology, January 2007, PLOS

    Dr Marcelo A Carvalho

  34. The P1812A and P25TBRCA1and the 5164del4BRCA2Mutations: Occurrence in High-Risk Non-Ashkenazi Jews

    Article • Genetic Testing, September 2006, Mary Ann Liebert Inc

    Dr Marcelo A Carvalho

  35. Breast Cancer Susceptibility and the DNA Damage Response

    Article • Cancer Control, April 2005, SAGE Publications

    Dr Marcelo A Carvalho

  36. Functional impact of missense variants in BRCA1 predicted by supervised learning

    Article • PLoS Computational Biology, January 2005, PLOS

    Dr Marcelo A Carvalho

  37. TGF β1 and PDGF AA override Collagen type I inhibition of proliferation in human liver connective tissue cells

    Article • BMC Gastroenterology, December 2004, Springer Science + Business Media

    Dr Marcelo A Carvalho

  38. Gap junctions in hematopoietic stroma control proliferation and differentiation of blood cell precursors

    Article • Anais da Academia Brasileira de Ciências, December 2004, FapUNIFESP (SciELO)

    Dr Marcelo A Carvalho

  39. Stroma-mediated granulocyte-macrophage colony-stimulating factor (GM-CSF) control of myelopoiesis: spatial organisation of intercellular interactions

    Article • Cell and Tissue Research, June 2003, Springer Science + Business Media

    PhD JOSE DIAS CORREA JUNIOR, Dr Marcelo A Carvalho

  40. The capacity of connective tissue stromas to sustain myelopoiesis depends both upon the growth factors and the local intercellular environment

    Article • Biology of the Cell, December 2000, Wiley

    Dr Marcelo A Carvalho

  41. Acidic pH Modulates the Interaction between Human Granulocyte-Macrophage Colony-stimulating Factor and Glycosaminoglycans

    Article • Journal of Biological Chemistry, October 1999, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Marcelo A Carvalho