All Stories

  1. In vitro exercise model using contractile human and mouse hybrid myotubes

    Article • Scientific Reports, August 2019, Springer Science + Business Media

    Makoto Kanzaki

  2. Sparc, an EPS-induced gene, modulates the extracellular matrix and mitochondrial function via ILK/AMPK pathways in C2C12 cells

    Article • Life Sciences, July 2019, Elsevier

    Makoto Kanzaki

  3. Extracellular α-synuclein enters dopaminergic cells by modulating flotillin-1–assisted dopamine transporter endocytosis

    Article • The FASEB Journal, June 2019, Federation of American Societies For Experimental Biology (FASEB)

    Atsushi Takeda, Mitsunori Fukuda, Makoto Kanzaki, Takafumi Hasegawa

  4. Cooperative actions of Tbc1d1 and AS160/Tbc1d4 in GLUT4-trafficking activities

    Article • Journal of Biological Chemistry, November 2018, American Society for Biochemistry & Molecular Biology (ASBMB)

    Makoto Kanzaki

  5. Prior treatment with the AMPK activator AICAR induces subsequently enhanced glucose uptake in isolated skeletal muscles from 24-month-old rats

    Article • Applied Physiology Nutrition and Metabolism, August 2018, Canadian Science Publishing

    Makoto Kanzaki

  6. Roles of IL-1α/β in regeneration of cardiotoxin-injured muscle and satellite cell function

    Article • AJP Regulatory Integrative and Comparative Physiology, July 2018, American Physiological Society

    Makoto Kanzaki

  7. Neutrophils Provide a Favorable IL-1-Mediated Immunometabolic Niche that Primes GLUT4 Translocation and Performance in Skeletal Muscles

    Article • Cell Reports, May 2018, Elsevier

    Makoto Kanzaki

  8. Contractile Skeletal Muscle Cells Cultured with a Conducting Soft Wire for Effective, Selective Stimulation

    Article • Scientific Reports, February 2018, Springer Science + Business Media

    Makoto Kanzaki

  9. Olfactory receptors are expressed in pancreatic β-cells and promote glucose-stimulated insulin secretion

    Article • Scientific Reports, January 2018, Springer Science + Business Media

    Makoto Kanzaki

  10. Involvement of neutrophils and interleukin-18 in nociception in a mouse model of muscle pain

    Article • Molecular Pain, January 2018, SAGE Publications

    Makoto Kanzaki

  11. Retained Myogenic Potency of Human Satellite Cells from Torn Rotator Cuff Muscles Despite Fatty Infiltration

    Article • The Tohoku Journal of Experimental Medicine, January 2018, Tohoku University Medical Press

    Makoto Kanzaki

  12. Three-Dimensional Tracking of Quantum Dot-Conjugated Molecules in Living Cells

    Article • January 2018, Springer Science + Business Media

    Makoto Kanzaki

  13. Neuronal signals regulate obesity induced β-cell proliferation by FoxM1 dependent mechanism

    Article • Nature Communications, December 2017, Springer Science + Business Media

    Makoto Kanzaki

  14. Direct plasma stimuli including electrostimulation and OH radical induce transient increase in intracellular Ca2+ and uptake of a middle-size membrane-impermeable molecule

    Article • Plasma Processes and Polymers, August 2017, Wiley

    Shota Sasaki, Makoto Kanzaki

  15. Heterotypic endosomal fusion as an initial trigger for insulin-induced glucose transporter 4 (GLUT4) translocation in skeletal muscle

    Article • The Journal of Physiology, July 2017, Wiley

    Makoto Kanzaki

  16. 3D electrochemical and ion current imaging using scanning electrochemical–scanning ion conductance microscopy

    Article • Physical Chemistry Chemical Physics, January 2017, Royal Society of Chemistry

    Makoto Kanzaki

  17. Gas-liquid interfacial plasmas producing reactive species for cell membrane permeabilization

    Article • Journal of Clinical Biochemistry and Nutrition, January 2017, The Society for Free Radical Research Japan

    Makoto Kanzaki

  18. Live-cell single-molecule labeling and analysis of myosin motors with quantum dots

    Article • Molecular Biology of the Cell, January 2017, American Society for Cell Biology (ASCB)

    Makoto Kanzaki

  19. Characterization of plasma-induced cell membrane permeabilization: focus on OH radical distribution

    Article • Journal of Physics D Applied Physics, July 2016, Institute of Physics Publishing

    Makoto Kanzaki

  20. The proneurotrophin receptor sortilin is required for Mycobacterium tuberculosis control by macrophages

    Article • Scientific Reports, July 2016, Springer Science + Business Media

    Makoto Kanzaki

  21. Roles of charged particles and reactive species on cell membrane permeabilization induced by atmospheric-pressure plasma irradiation

    Article • Japanese Journal of Applied Physics, June 2016, Japan Society of Applied Physics

    Makoto Kanzaki

  22. Plasma-irradiated solution as drug permeation enhancer

    Article • June 2016, Institute of Electrical & Electronics Engineers (IEEE)

    Makoto Kanzaki

  23. Calcium influx through TRP channels induced by short-lived reactive species in plasma-irradiated solution

    Article • Scientific Reports, May 2016, Springer Science + Business Media

    Makoto Kanzaki

  24. Involvement of IL-1 in the Maintenance of Masseter Muscle Activity and Glucose Homeostasis

    Article • PLoS ONE, November 2015, PLOS

    Makoto Kanzaki

  25. Improvement of cell membrane permeability using a cell-solution electrode for generating atmospheric-pressure plasma

    Article • Biointerphases, June 2015, American Vacuum Society

    Makoto Kanzaki

  26. Insulin-Mimicking Bioactivities of Acylated Inositol Glycans in Several Mouse Models of Diabetes with or without Obesity

    Article • PLoS ONE, June 2014, PLOS

    Makoto Kanzaki

  27. Highly efficient and minimally invasive transfection using time-controlled irradiation of atmospheric-pressure plasma

    Article • Applied Physics Express, January 2014, Institute of Physics Publishing

    Makoto Kanzaki

  28. Hydrogel-based bioassay sheets for in vitro evaluation of contraction-dependent metabolic regulation in skeletal muscle cells

    Article • Biomaterials Science, January 2014, Royal Society of Chemistry

    Makoto Kanzaki

  29. Expression, phosphorylation and function of the Rab-GTPase activating protein TBC1D1 in pancreatic beta-cells

    Article • FEBS Letters, November 2013, Wiley

    Makoto Kanzaki

  30. Development of dual-color simultaneous single molecule imaging system for analyzing multiple intracellular trafficking activities

    Article • July 2013, Institute of Electrical & Electronics Engineers (IEEE)

    Makoto Kanzaki

  31. Single Quantum Dot Tracking Reveals that an Individual Multivalent HIV-1 Tat Protein Transduction Domain Can Activate Machinery for Lateral Transport and Endocytosis

    Article • Molecular and Cellular Biology, June 2013, ASM Journals

    Chandra Nath Roy, Makoto Kanzaki

  32. Regulatory mode shift of Tbc1d1 is required for acquisition of insulin-responsive GLUT4-trafficking activity

    Article • Molecular Biology of the Cell, March 2013, American Society for Cell Biology (ASCB)

    Makoto Kanzaki

  33. Characterization of contraction-induced IL-6 up-regulation using contractile C2C12 myotubes

    Article • Endocrine Journal, January 2013, Japan Endocrine Society

    Makoto Kanzaki

  34. Hydrogel-supported skeletal muscle cell-based bioassay system

    Article • November 2011, Institute of Electrical & Electronics Engineers (IEEE)

    Makoto Kanzaki

  35. Molecular Basis of Insulin-Responsive GLUT4 Trafficking Systems Revealed by Single Molecule Imaging

    Article • Traffic, October 2011, Wiley

    Makoto Kanzaki

  36. Clustering of GLUT4, TUG, and RUVBL2 protein levels correlate with myosin heavy chain isoform pattern in skeletal muscles, but AS160 and TBC1D1 levels do not

    Article • Journal of Applied Physiology, October 2011, American Physiological Society

    Makoto Kanzaki

  37. Non-muscle myosin II induces disassembly of actin stress fibres independently of myosin light chain dephosphorylation

    Article • Interface Focus, August 2011, Royal Society Publishing

    Makoto Kanzaki

  38. Spatiotemporally controlled contraction of micropatterned skeletal muscle cells on a hydrogel sheet

    Article • Lab on a Chip, January 2011, Royal Society of Chemistry

    Makoto Kanzaki

  39. Electrically induced contraction of C2C12 myotubes cultured on a porous membrane-based substrate with muscle tissue-like stiffness

    Article • Biomaterials, September 2010, Elsevier

    Makoto Kanzaki

  40. Palmitate-induced Down-regulation of Sortilin and Impaired GLUT4 Trafficking in C2C12 Myotubes

    Article • Journal of Biological Chemistry, August 2010, American Society for Biochemistry & Molecular Biology (ASBMB)

    Makoto Kanzaki

  41. Identification of Three Distinct Functional Sites of Insulin-mediated GLUT4 Trafficking in Adipocytes Using Quantitative Single Molecule Imaging

    Article • Molecular Biology of the Cell, August 2010, American Society for Cell Biology (ASCB)

    Makoto Kanzaki

  42. Role of p120-catenin in the morphological changes of endothelial cells exposed to fluid shear stress

    Article • Biochemical and Biophysical Research Communications, July 2010, Elsevier

    Makoto Kanzaki

  43. In vivo exercise followed by in vitro contraction additively elevates subsequent insulin-stimulated glucose transport by rat skeletal muscle

    Article • AJP Endocrinology and Metabolism, May 2010, American Physiological Society

    Makoto Kanzaki

  44. Topographic imaging of convoluted surface of live cells by scanning ion conductance microscopy in a standing approach mode

    Article • Physical Chemistry Chemical Physics, January 2010, Royal Society of Chemistry

    Makoto Kanzaki

  45. Metabolic Assay System for Micropatterned Contractile Myotubes

    Article • January 2010, The Electrochemical Society

    Makoto Kanzaki

  46. Micropatterning contractile C2C12myotubes embedded in a fibrin gel

    Article • Biotechnology and Bioengineering, January 2010, Wiley

    Makoto Kanzaki

  47. Different impacts of saturated and unsaturated free fatty acids on COX-2 expression in C2C12 myotubes

    Article • AJP Endocrinology and Metabolism, December 2009, American Physiological Society

    Makoto Kanzaki

  48. Characterization of contraction-inducible CXC chemokines and their roles in C2C12 myocytes

    Article • AJP Endocrinology and Metabolism, October 2009, American Physiological Society

    Makoto Kanzaki

  49. Increased AS160 phosphorylation, but not TBC1D1 phosphorylation, with increased postexercise insulin sensitivity in rat skeletal muscle

    Article • AJP Endocrinology and Metabolism, July 2009, American Physiological Society

    Makoto Kanzaki

  50. Exercising cultured myotubes

    Article • Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology, December 2008, Elsevier

    Makoto Kanzaki

  51. Contractile C2C12 myotube model for studying exercise-inducible responses in skeletal muscle

    Article • AJP Endocrinology and Metabolism, November 2008, American Physiological Society

    Makoto Kanzaki

  52. Localized electrical stimulation to C2C12 myotubes cultured on a porous membrane-based substrate

    Article • Biomedical Microdevices, October 2008, Springer Science + Business Media

    Makoto Kanzaki

  53. Ambient glucose levels qualify the potency of insulin myogenic actions by regulating SIRT1 and FoxO3a in C2C12 myocytes

    Article • AJP Endocrinology and Metabolism, April 2008, American Physiological Society

    Makoto Kanzaki

  54. Functional Role of Sortilin in Myogenesis and Development of Insulin-responsive Glucose Transport System in C2C12 Myocytes

    Article • Journal of Biological Chemistry, February 2008, American Society for Biochemistry & Molecular Biology (ASBMB)

    Makoto Kanzaki

  55. Electric Pulse Stimulation Induces NMDA Glutamate Receptor mRNA in NIH3T3 Mouse Fibroblasts

    Article • The Tohoku Journal of Experimental Medicine, January 2008, Tohoku University Medical Press

    Makoto Kanzaki

  56. [Erratum] Electric Pulse Stimulation Induces NMDA Glutamate Receptor mRNA in NIH3T3 Mouse Fibroblasts

    Article • The Tohoku Journal of Experimental Medicine, January 2008, Tohoku University Medical Press

    Makoto Kanzaki

  57. Accelerated de novo sarcomere assembly by electric pulse stimulation in C2C12 myotubes

    Article • Experimental Cell Research, May 2007, Elsevier

    Makoto Kanzaki

  58. Involvement of Apolipoprotein E in Excess Fat Accumulation and Insulin Resistance

    Article • Diabetes, December 2006, American Diabetes Association

    Makoto Kanzaki

  59. Regulation of glucose transporters by insulin and extracellular glucose in C2C12 myotubes

    Article • AJP Endocrinology and Metabolism, October 2006, American Physiological Society

    Makoto Kanzaki

  60. Insulin Receptor Signals Regulating GLUT4 Translocation and Actin Dynamics

    Article • Endocrine Journal, January 2006, Japan Endocrine Society

    Makoto Kanzaki

  61. Entry of newly synthesized GLUT4 into the insulin-responsive storage compartment is GGA dependent

    Article • The EMBO Journal, April 2004, Wiley

    Makoto Kanzaki

  62. Phosphatidylinositol 4,5-Bisphosphate Regulates Adipocyte Actin Dynamics and GLUT4 Vesicle Recycling

    Article • Journal of Biological Chemistry, April 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Makoto Kanzaki

  63. Regulated Membrane Trafficking of the Insulin-Responsive Glucose Transporter 4 in Adipocytes

    Article • Endocrine Reviews, April 2004, Endocrine Society

    Makoto Kanzaki

  64. Atypical protein kinase C (PKCζ/λ) is a convergent downstream target of the insulin-stimulated phosphatidylinositol 3-kinase and TC10 signaling pathways

    Article • The Journal of Cell Biology, January 2004, Rockefeller University Press

    Makoto Kanzaki

  65. Insulin Signaling: GLUT4 Vesicles Exit via the Exocyst

    Article • Current Biology, July 2003, Elsevier

    Makoto Kanzaki

  66. The Exocytotic Trafficking of TC10 Occurs through both Classical and Nonclassical Secretory Transport Pathways in 3T3L1 Adipocytes

    Article • Molecular and Cellular Biology, February 2003, ASM Journals

    Makoto Kanzaki

  67. A Crk-II/TC10 Signaling Pathway Is Required For Osmotic Shock-stimulated Glucose Transport

    Article • Journal of Biological Chemistry, September 2002, American Society for Biochemistry & Molecular Biology (ASBMB)

    Makoto Kanzaki

  68. Small GTP-binding Protein TC10 Differentially Regulates Two Distinct Populations of Filamentous Actin in 3T3L1 Adipocytes

    Article • Molecular Biology of the Cell, July 2002, American Society for Cell Biology (ASCB)

    Makoto Kanzaki

  69. Caveolin-associated Filamentous Actin (Cav-actin) Defines a Novel F-actin Structure in Adipocytes

    Article • Journal of Biological Chemistry, May 2002, American Society for Biochemistry & Molecular Biology (ASBMB)

    Makoto Kanzaki

  70. Intracellular Insulin-Responsive Glucose Transporter (GLUT4) Distribution But Not Insulin-Stimulated GLUT4 Exocytosis and Recycling Are Microtubule Dependent

    Article • Molecular Endocrinology, May 2002, Endocrine Society

    Makoto Kanzaki

  71. Intracellular Insulin-Responsive Glucose Transporter (GLUT4) Distribution But Not Insulin-Stimulated GLUT4 Exocytosis and Recycling Are Microtubule Dependent

    Article • Molecular Endocrinology, May 2002, Endocrine Society

    Makoto Kanzaki

  72. Functional Dissection of Lipid and Protein Kinase Signals of PIKfyve Reveals the Role of PtdIns 3,5-P2Production for Endomembrane Integrity

    Article • Journal of Biological Chemistry, November 2001, American Society for Biochemistry & Molecular Biology (ASBMB)

    Makoto Kanzaki

  73. Insulin Stimulates Actin Comet Tails on Intracellular GLUT4-containing Compartments in Differentiated 3T3L1 Adipocytes

    Article • Journal of Biological Chemistry, October 2001, American Society for Biochemistry & Molecular Biology (ASBMB)

    Makoto Kanzaki

  74. Insulin-stimulated GLUT4 Translocation in Adipocytes Is Dependent upon Cortical Actin Remodeling

    Article • Journal of Biological Chemistry, September 2001, American Society for Biochemistry & Molecular Biology (ASBMB)

    Makoto Kanzaki

  75. Lipid raft microdomain compartmentalization of TC10 is required for insulin signaling and GLUT4 translocation

    Article • The Journal of Cell Biology, August 2001, Rockefeller University Press

    Makoto Kanzaki

  76. Identification of a Novel Chloride Channel Expressed in the Endoplasmic Reticulum, Golgi Apparatus, and Nucleus

    Article • Journal of Biological Chemistry, March 2001, American Society for Biochemistry & Molecular Biology (ASBMB)

    Makoto Kanzaki

  77. Signal Integration and the Specificity of Insulin Action

    Article • Cell Biochemistry and Biophysics, January 2001, Springer Science + Business Media

    Makoto Kanzaki

  78. Report Clarification

    Article • Science, May 2000, American Association for the Advancement of Science

    Makoto Kanzaki

  79. The Trimeric GTP-binding Protein (Gq/G11) α Subunit Is Required for Insulin-stimulated GLUT4 Translocation in 3T3L1 Adipocytes

    Article • Journal of Biological Chemistry, March 2000, American Society for Biochemistry & Molecular Biology (ASBMB)

    Makoto Kanzaki

  80. Munc18c Function Is Required for Insulin-Stimulated Plasma Membrane Fusion of GLUT4 and Insulin-Responsive Amino Peptidase Storage Vesicles

    Article • Molecular and Cellular Biology, January 2000, ASM Journals

    Makoto Kanzaki

  81. Molecular Identification of a Eukaryotic, Stretch-Activated Nonselective Cation Channel

    Article • Science, August 1999, American Association for the Advancement of Science

    Makoto Kanzaki

  82. Synip

    Article • Molecular Cell, June 1999, Elsevier

    Makoto Kanzaki

  83. Studies on the betacellulin receptor in pancreatic AR42J cells

    Article • Diabetologia, May 1998, Springer Science + Business Media

    Makoto Kanzaki

  84. Activation of Calcium-Permeable Cation Channel by Insulin in Chinese Hamster Ovary Cells Expressing Human Insulin Receptors1

    Article • Endocrinology, January 1998, Endocrine Society

    Makoto Kanzaki

  85. Activation of Calcium-Permeable Cation Channel by Insulin in Chinese Hamster Ovary Cells Expressing Human Insulin Receptors

    Article • Endocrinology, January 1998, Endocrine Society

    Makoto Kanzaki

  86. Regulation of the expression of follistatin in rat hepatocytes

    Article • Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, November 1997, Elsevier

    Makoto Kanzaki

  87. Activation of the Calcium-permeable Cation Channel CD20 by α Subunits of the GiProtein

    Article • Journal of Biological Chemistry, June 1997, American Society for Biochemistry & Molecular Biology (ASBMB)

    Makoto Kanzaki

  88. Assessment of the role of activin A and transforming growth factor ? in the regulation of AML12 cell growth

    Article • Hepatology, June 1997, Wiley

    Makoto Kanzaki

  89. Activation of a Calcium-permeable Cation Channel CD20 Expressed in Balb/c 3T3 Cells by Insulin-like Growth Factor-I

    Article • Journal of Biological Chemistry, February 1997, American Society for Biochemistry & Molecular Biology (ASBMB)

    Makoto Kanzaki

  90. Characterization of the activin receptor in cultured rat hepatocytes

    Article • Hepatology, August 1996, Wiley

    Makoto Kanzaki

  91. Intravenous administration of follistatin: Delivery to the liver and effect on liver regeneration after partial hepatectomy

    Article • Hepatology, August 1996, Wiley

    Makoto Kanzaki

  92. Characterization of the activin receptor in cultured rat hepatocytes

    Article • Hepatology, August 1996, Wiley

    Makoto Kanzaki

  93. Two distinct signaling pathways activated by activin A in glucose-responsive pancreatic  -cell lines

    Article • Journal of Molecular Endocrinology, June 1996, Bioscientifica

    Makoto Kanzaki

  94. Calcium as a second messenger of the action of transforming growth factor-β on insulin secretion

    Article • Molecular and Cellular Endocrinology, March 1996, Elsevier

    Makoto Kanzaki

  95. Growth or Differentiation: Determination by FSH of the Action of Insulin-Like Growth Factor-I in Cultured Rat Granulosa Cells.

    Article • Endocrine Journal, January 1996, Japan Endocrine Society

    Makoto Kanzaki

  96. Production of activin a in human intestinal epithelial cell line

    Article • Digestive Diseases and Sciences, October 1995, Springer Science + Business Media

    Makoto Kanzaki

  97. Modulation of adenosine triphosphate-sensitive potassium channel and voltage-dependent calcium channel by activin A in HIT-T15 cells

    Article • Endocrinology, July 1995, Endocrine Society

    Makoto Kanzaki

  98. Modulation of adenosine triphosphate-sensitive potassium channel and voltage-dependent calcium channel by activin A in HIT-T15 cells.

    Article • Endocrinology, July 1995, Endocrine Society

    Makoto Kanzaki

  99. Expression of Calcium-permeable Cation Channel CD20 Accelerates Progression through the G1Phase in Balb/c 3T3 Cells

    Article • Journal of Biological Chemistry, June 1995, American Society for Biochemistry & Molecular Biology (ASBMB)

    Makoto Kanzaki

  100. A single intraportal administration of follistatin accelerates liver regeneration in partially hepatectomized rats

    Article • Gastroenterology, April 1995, Elsevier

    Makoto Kanzaki

  101. Derangements in the activin-follistatin system in hepatoma cells

    Article • Gastroenterology, March 1995, Elsevier

    Makoto Kanzaki

  102. A SENSITIVE, NON-ISOTOPIC IMMUNOASSAY FOR PROGESTERONE USING THE AVIDIN-BIOTIN SYSTEM

    Article • Biomedical Research, January 1995, Biomedical Research Press

    Makoto Kanzaki

  103. Stimulation of Follistatin Production by Epidermal Growth Factor in Cultured Rat Hepatocytes

    Article • Biochemical and Biophysical Research Communications, July 1994, Elsevier

    Makoto Kanzaki

  104. Human growth hormone augmentation of epidermal growth factor binding sites on rat granulosa cells

    Article • Journal of Endocrinology, July 1994, Bioscientifica

    Makoto Kanzaki

  105. Basic fibroblast growth factor induces luteinizing hormone receptor expression in the presence of insulin-like growth factor-I in ovarian granulosa cells

    Article • Molecular and Cellular Endocrinology, May 1994, Elsevier

    Makoto Kanzaki

  106. Co-ordinate actions of FSH and insulin-like growth factor-I on LH receptor expression in rat granulosa cells

    Article • Journal of Endocrinology, May 1994, Bioscientifica

    Makoto Kanzaki

  107. Granulosa cell luteinizing hormone receptor expression is modulated by ganglioside-specific ligands

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, March 1994, Elsevier

    Makoto Kanzaki

  108. Subcellular Compartmentalization of Insulin Signaling Processes and GLUT4 Trafficking Events

    Article • Springer Science + Business Media

    Makoto Kanzaki