All Stories

  1. A novel inactivated oral rabies vaccine with the incorporation of U-OMP19 enhances the immunogenicity by reducing viral proteins degradation and activating dendritic cells in a mouse model

    Article • Veterinary Microbiology, November 2024, Elsevier

    Professor Ling Zhao

  2. Z-Ligustilide restricts rabies virus replication by inducing ferroptosis through the ACSL4-LPCAT3-POR pathway

    Article • Veterinary Microbiology, November 2024, Elsevier

    Professor Ling Zhao

  3. CXCL13 promotes broad immune responses induced by circular RNA vaccines

    Article • Proceedings of the National Academy of Sciences, October 2024, Proceedings of the National Academy of Sciences

    Ling Zhao, Professor Ling Zhao

  4. Generation of canine neutralizing antibodies against canine parvovirus by single B cell antibody technology

    Article • Archives of Virology, October 2024, Springer Science + Business Media

    Professor Ling Zhao

  5. AP3B1 facilitates PDIA3/ERP57 function to regulate rabies virus glycoprotein selective degradation and viral entry

    Article • Autophagy, August 2024, Taylor & Francis

    Professor Ling Zhao

  6. A cocktail of engineered chimeric antibodies targeting the central nervous system produces a broad-spectrum therapeutic effect for symptomatic rabies

    Article • August 2024, Springer Science + Business Media

    Professor Ling Zhao

  7. RTP4 restricts lyssavirus rabies infection by binding to viral genomic RNA

    Article • Veterinary Microbiology, August 2024, Elsevier

    Professor Ling Zhao

  8. hnRNPAB inhibits Influenza A virus infection by disturbing polymerase activity

    Article • Antiviral Research, August 2024, Elsevier

    Professor Ling Zhao

  9. Focus on pet diseases

    Article • Animal Diseases, July 2024, Springer Science + Business Media

    Professor Ling Zhao

  10. Lassa virus Z protein hijacks the autophagy machinery for efficient transportation by interrupting CCT2-mediated cytoskeleton network formation

    Article • Autophagy, July 2024, Taylor & Francis

    Professor Ling Zhao

  11. Lyssavirus matrix protein inhibits NLRP3 inflammasome assembly by binding to NLRP3

    Article • Cell Reports, July 2024, Elsevier

    Professor Ling Zhao

  12. Rapid diagnosis of canine respiratory coronavirus, canine influenza virus, canine distemper virus and canine parainfluenza virus with a Taqman probe-based multiplex real-time PCR

    Article • Journal of Virological Methods, July 2024, Elsevier

    Professor Ling Zhao

  13. TLR9 promotes monocytic myeloid-derived suppressor cell induction during JEV infection

    Article • Microbes and Infection, July 2024, Elsevier

    Professor Ling Zhao

  14. Investigation of the epidemiology, pathogenicity and immunogenicity of Bordetella bronchiseptica isolated from cats and dogs in China from 2021 to 2023

    Article • Animal Diseases, May 2024, Springer Science + Business Media

    Professor Ling Zhao

  15. A broadly applicable protein-polymer adjuvant system for antiviral vaccines

    Article • EMBO Molecular Medicine, May 2024, Springer Science + Business Media

    Professor Ling Zhao

  16. The matrix protein of lyssavirus hijacks autophagosome for efficient egress by recruiting NEDD4 through its PPxY motif

    Article • Autophagy, April 2024, Taylor & Francis

    Professor Ling Zhao

  17. Neuroinvasive virus facilitates viral replication by employing lipid droplets to reduce arachidonic acid-induced ferroptosis

    Article • Journal of Biological Chemistry, April 2024, Elsevier

    Professor Ling Zhao

  18. Lyssavirus M protein degrades neuronal microtubules by reprogramming mitochondrial metabolism

    Article • mBio, March 2024, ASM Journals

    Professor Ling Zhao

  19. TRIM72 restricts lyssavirus infection by inducing K48-linked ubiquitination and proteasome degradation of the matrix protein

    Article • PLoS Pathogens, February 2024, PLOS

    Professor Ling Zhao

  20. Interleukin-7 potentiates MAPK10-elicited host-protective vaccine against Leishmania donovani

    Article • Cytokine, February 2024, Elsevier

    Professor Ling Zhao

  21. Cholesterol depletion inhibits rabies virus infection by restricting viral adsorption and fusion

    Article • Veterinary Microbiology, February 2024, Elsevier

    Professor Ling Zhao

  22. A modified recombinant adenovirus vector containing dual rabies virus G expression cassettes confers robust and long-lasting humoral immunity in mice, cats, and dogs

    Article • Emerging Microbes & Infections, January 2024, Taylor & Francis

    Professor Ling Zhao

  23. Circular RNA vaccines with long-term lymph node-targeting delivery stability after lyophilization induce potent and persistent immune responses

    Article • mBio, January 2024, ASM Journals

    Professor Ling Zhao

  24. A single immunization with core–shell structured lipopolyplex mRNA vaccine against rabies induces potent humoral immunity in mice and dogs

    Article • Emerging Microbes & Infections, November 2023, Taylor & Francis

    Professor Ling Zhao

  25. Yeast Peptides Improve the Intestinal Barrier Function and Alleviate Weaning Stress by Changing the Intestinal Microflora Structure of Weaned Lambs

    Article • Microorganisms, October 2023, MDPI AG

    Professor Ling Zhao

  26. Transdermal delivery of Fluoropolymer-Modified microneedle vaccines against rabies elicits potent humoral immunity

    Article • Chemical Engineering Journal, October 2023, Elsevier

    Professor Ling Zhao

  27. TRIM72 restricts lyssavirus infection by inducing K48-linked ubiquitination and proteasome degradation of the matrix protein

    Article • September 2023, Cold Spring Harbor Laboratory Press

    Professor Ling Zhao

  28. The CH24H metabolite, 24HC, blocks viral entry by disrupting intracellular cholesterol homeostasis

    Article • Redox Biology, August 2023, Elsevier

    Professor Ling Zhao

  29. Short-Chain Fatty Acids Alleviate Vancomycin-Caused Humoral Immunity Attenuation in Rabies-Vaccinated Mice by Promoting the Generation of Plasma Cells via Akt-mTOR Pathway

    Article • Journal of Virology, July 2023, ASM Journals

    Professor Ling Zhao

  30. Inhibition of miR-200b-3p confers broad-spectrum resistance to viral infection by targeting TBK1

    Article • mBio, May 2023, ASM Journals

    Professor Ling Zhao

  31. A novel epitope tag from rabies virus has versatile in vitro applications

    Article • Applied Microbiology and Biotechnology, May 2023, Springer Science + Business Media

    Professor Ling Zhao

  32. Interleukin-1β suppresses rabies virus infection by activating cGAS-STING pathway and compromising the blood-brain barrier integrity in mice

    Article • Veterinary Microbiology, May 2023, Elsevier

    Professor Ling Zhao

  33. Resistin secreted by porcine alveolar macrophages leads to endothelial cell dysfunction during Haemophilus parasuis infection

    Article • Virulence, February 2023, Taylor & Francis

    Professor Ling Zhao

  34. Substitution of S179P in the Lyssavirus Phosphoprotein Impairs Its Interferon Antagonistic Function

    Article • Journal of Virology, November 2022, ASM Journals

    Professor Ling Zhao

  35. Trim25 restricts rabies virus replication by destabilizing phosphoprotein

    Article • Cell Insight, October 2022, Elsevier

    Professor Ling Zhao

  36. Regulation of innate immune responses by rabies virus

    Article • Animal Models and Experimental Medicine, September 2022, Wiley

    Professor Ling Zhao

  37. Lab-Attenuated Rabies Virus Facilitates Opening of the Blood-Brain Barrier by Inducing Matrix Metallopeptidase 8

    Article • Journal of Virology, September 2022, ASM Journals

    Professor Ling Zhao

  38. A single dose of recombinant VSV-RABVG vaccine provides full protection against RABV challenge

    Article • Virologica Sinica, June 2022, Elsevier

    Professor Ling Zhao

  39. Dual-Mode Immunosensor for Electrochemiluminescence Resonance Energy Transfer and Electrochemical Detection of Rabies Virus Glycoprotein Based on Ru(bpy)32+-Loaded Dendritic Mesoporous Silica Nanoparticles

    Article • Analytical Chemistry, May 2022, American Chemical Society (ACS)

    Professor Ling Zhao

  40. Meningeal lymphatic vessels mediate neurotropic viral drainage from the central nervous system

    Article • Nature Neuroscience, May 2022, Springer Science + Business Media

    Professor Ling Zhao

  41. Binding induced isothermal amplification reaction to activate CRISPR/Cas12a for amplified electrochemiluminescence detection of rabies viral RNA via DNA nanotweezer structure switching

    Article • Biosensors and Bioelectronics, May 2022, Elsevier

    Professor Ling Zhao

  42. Effective cross-protection of a lyophilized live gE/gI/TK-deleted pseudorabies virus (PRV) vaccine against classical and variant PRV challenges

    Article • Veterinary Microbiology, April 2022, Elsevier

    Professor Ling Zhao

  43. lncRNA EDAL restricts rabies lyssavirus replication in a cell-specific and infection route-dependent manner

    Article • Journal of General Virology, March 2022, Society for General Microbiology

    Professor Ling Zhao

  44. Comprehensive Analysis of Protein Acetylation and Glucose Metabolism in Mouse Brains Infected with Rabies Virus

    Article • Journal of Virology, February 2022, ASM Journals

    Professor Ling Zhao

  45. G protein-coupled receptor 17 restricts rabies virus replication via BAK-mediated apoptosis

    Article • Veterinary Microbiology, February 2022, Elsevier

    Professor Ling Zhao

  46. Lipid Droplets Are Beneficial for Rabies Virus Replication by Facilitating Viral Budding

    Article • Journal of Virology, January 2022, ASM Journals

    Professor Ling Zhao

  47. A spatial and cellular distribution of rabies virus infection in the mouse brain revealed by fMOST and single‐cell RNA sequencing

    Article • Clinical and Translational Medicine, January 2022, Wiley

    Professor Ling Zhao

  48. Overexpression of Interleukin-33 in Recombinant Rabies Virus Enhances Innate and Humoral Immune Responses through Activation of Dendritic Cell-Germinal Center Reactions

    Article • Vaccines, December 2021, MDPI AG

    Professor Ling Zhao

  49. Toll-Like Receptor 4 Regulates Rabies Virus-Induced Humoral Immunity through Recruitment of Conventional Type 2 Dendritic Cells to Lymph Organs

    Article • Journal of Virology, November 2021, ASM Journals

    Professor Ling Zhao

  50. Colloidal Manganese Salt Improves the Efficacy of Rabies Vaccines in Mice, Cats, and Dogs

    Article • Journal of Virology, November 2021, ASM Journals

    Professor Ling Zhao

  51. PABPC4 Broadly Inhibits Coronavirus Replication by Degrading Nucleocapsid Protein through Selective Autophagy

    Article • Microbiology Spectrum, October 2021, ASM Journals

    Professor Ling Zhao

  52. The role of interferon regulatory factor 7 in the pathogenicity and immunogenicity of rabies virus in a mouse model

    Article • Journal of General Virology, October 2021, Society for General Microbiology

    Professor Ling Zhao

  53. Virus-Like Vesicles Based on Semliki Forest Virus-Containing Rabies Virus Glycoprotein Make a Safe and Efficacious Rabies Vaccine Candidate in a Mouse Model

    Article • Journal of Virology, September 2021, ASM Journals

    Professor Ling Zhao

  54. Preexposure and Postexposure Prophylaxis of Rabies With Adeno-Associated Virus Expressing Virus-Neutralizing Antibody in Rodent Models

    Article • Frontiers in Microbiology, August 2021, Frontiers

    Professor Ling Zhao

  55. Murine Ifit3 restricts the replication of Rabies virus both in vitro and in vivo

    Article • Journal of General Virology, July 2021, Society for General Microbiology

    Professor Ling Zhao

  56. The Pathogenic Features of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): Possible Mechanisms for Immune Evasion?

    Article • Frontiers in Immunology, July 2021, Frontiers

    Professor Ling Zhao

  57. Aptamer and RVG functionalized gold nanorods for targeted photothermal therapy of neurotropic virus infection in the mouse brain

    Article • Chemical Engineering Journal, May 2021, Elsevier

    Professor Ling Zhao

  58. Comparison of lncRNA and mRNA expression in mouse brains infected by a wild-type and a lab-attenuated Rabies lyssavirus

    Article • Journal of General Virology, March 2021, Society for General Microbiology

    Professor Ling Zhao

  59. Early diagnosis of rabies virus infection by RPA-CRISPR techniques in a rat model

    Article • Archives of Virology, February 2021, Springer Science + Business Media

    Professor Ling Zhao

  60. Development of A Super-Sensitive Diagnostic Method for African Swine Fever Using CRISPR Techniques

    Article • Virologica Sinica, January 2021, Elsevier

    Professor Ling Zhao

  61. A novel oral rabies vaccine enhances the immunogenicity through increasing dendritic cells activation and germinal center formation by expressing U-OMP19 in a mouse model

    Article • Emerging Microbes & Infections, January 2021, Taylor & Francis

    Professor Ling Zhao

  62. P38 mitogen-activated protein kinase promotes Wnt/β-catenin signaling by impeding Dickkofp-1 expression during Haemophilus parasuis infection

    Article • Cytokine, December 2020, Elsevier

    Professor Ling Zhao

  63. Isolation and evolutionary analyses of porcine epidemic diarrhea virus in Asia

    Article • PeerJ, October 2020, PeerJ

    Professor Ling Zhao

  64. Interferon-Inducible GTPase 1 Impedes the Dimerization of Rabies Virus Phosphoprotein and Restricts Viral Replication

    Article • Journal of Virology, October 2020, ASM Journals

    Professor Ling Zhao

  65. Different rabies outbreaks on two beef cattle farms in the same province of China: Diagnosis, virus characterization and epidemiological analysis

    Article • Transboundary and Emerging Diseases, September 2020, Hindawi Publishing Corporation

    Professor Ling Zhao

  66. A novel antiviral lncRNA, EDAL, shields a T309 O-GlcNAcylation site to promote EZH2 lysosomal degradation

    Article • September 2020, Springer Science + Business Media

    Professor Ling Zhao

  67. Composition of the murine gut microbiome impacts humoral immunity induced by rabies vaccines

    Article • Clinical and Translational Medicine, August 2020, Wiley

    Professor Ling Zhao

  68. A novel rabies vaccine based on infectious propagating particles derived from hybrid VEEV-Rabies replicon

    Article • EBioMedicine, June 2020, Elsevier

    Professor Ling Zhao

  69. Pomegranate-Inspired Silica Nanotags Enable Sensitive Dual-Modal Detection of Rabies Virus Nucleoprotein

    Article • Analytical Chemistry, May 2020, American Chemical Society (ACS)

    Professor Ling Zhao

  70. Dual Role of Toll-Like Receptor 7 in the Pathogenesis of Rabies Virus in a Mouse Model

    Article • Journal of Virology, April 2020, ASM Journals

    Professor Ling Zhao

  71. Interferon-λ Attenuates Rabies Virus Infection by Inducing Interferon-Stimulated Genes and Alleviating Neurological Inflammation

    Article • Viruses, April 2020, MDPI AG

    Professor Ling Zhao

  72. Recombinant Rabies Virus Overexpressing OX40-Ligand Enhances Humoral Immune Responses by Increasing T Follicular Helper Cells and Germinal Center B Cells

    Article • Vaccines, March 2020, MDPI AG

    Professor Ling Zhao

  73. Dual-mode amplified detection of rabies virus oligonucleotide via Y-shaped DNA assembly

    Article • Sensors and Actuators B Chemical, February 2020, Elsevier

    Professor Ling Zhao

  74. Monophosphoryl-Lipid A (MPLA) is an Efficacious Adjuvant for Inactivated Rabies Vaccines

    Article • Viruses, December 2019, MDPI AG

    Professor Ling Zhao

  75. EV71 infection induces neurodegeneration via activating TLR7 signaling and IL-6 production

    Article • PLoS Pathogens, November 2019, PLOS

    Professor Jianguo Wu, Professor Ling Zhao

  76. Cholesterol 25-hydroxylase suppresses rabies virus infection by inhibiting viral entry

    Article • Archives of Virology, September 2019, Springer Science + Business Media

    Professor Ling Zhao

  77. Codon optimization of G protein enhances rabies virus-induced humoral immunity

    Article • Journal of General Virology, August 2019, Society for General Microbiology

    Professor Ling Zhao

  78. A Recombinant Rabies Virus Expressing Fms-like Tyrosine Kinase 3 Ligand (Flt3L) Induces Enhanced Immunogenicity in Mice

    Article • Virologica Sinica, June 2019, Elsevier

    Professor Ling Zhao

  79. A recombinant canine distemper virus expressing interleukin-7 enhances humoral immunity

    Article • Journal of General Virology, April 2019, Society for General Microbiology

    Professor Ling Zhao

  80. Toll-Like Receptor 7 Enhances Rabies Virus-Induced Humoral Immunity by Facilitating the Formation of Germinal Centers

    Article • Frontiers in Immunology, March 2019, Frontiers

    Professor Ling Zhao

  81. Exhaustive Exercise Does Not Affect Humoral Immunity and Protection after Rabies Vaccination in a Mouse Model

    Article • Virologica Sinica, March 2018, Springer Science + Business Media

    Professor Ling Zhao

  82. Lab-Attenuated Rabies Virus Causes Abortive Infection and Induces Cytokine Expression in Astrocytes by Activating Mitochondrial Antiviral-Signaling Protein Signaling Pathway

    Article • Frontiers in Immunology, January 2018, Frontiers

    Professor Ling Zhao

  83. Recombinant rabies virus with the glycoprotein fused with a DC-binding peptide is an efficacious rabies vaccine

    Article • Oncotarget, December 2017, Impact Journals, LLC

    Professor Ling Zhao

  84. Recombinant rabies virus expressing IL-15 enhances immunogenicity through promoting the activation of dendritic cells in mice

    Article • Virologica Sinica, August 2017, Springer Science + Business Media

    Professor Ling Zhao

  85. An optimized HMGB1 expressed by recombinant rabies virus enhances immunogenicity through activation of dendritic cells in mice

    Article • Oncotarget, June 2017, Impact Journals, LLC

    Professor Ling Zhao

  86. The nucleocapsid proteins of mouse hepatitis virus and severe acute respiratory syndrome coronavirus share the same IFN-β antagonizing mechanism: attenuation of PACT-mediated RIG-I/ MDA5 activation

    Article • Oncotarget, May 2017, Impact Journals, LLC

    Professor Ling Zhao

  87. The ectodomain of rabies virus glycoprotein determines dendritic cell activation

    Article • Antiviral Research, May 2017, Elsevier

    Professor Ling Zhao

  88. TLR7 Deficiency Leads to TLR8 Compensative Regulation of Immune Response against JEV in Mice

    Article • Frontiers in Immunology, February 2017, Frontiers

    Professor Ling Zhao

  89. Overexpression of Interleukin-7 Extends the Humoral Immune Response Induced by Rabies Vaccination

    Article • Journal of Virology, January 2017, ASM Journals

    Professor Ling Zhao

  90. A Novel Rabies Vaccine Expressing CXCL13 Enhances Humoral Immunity by Recruiting both T Follicular Helper and Germinal Center B Cells

    Article • Journal of Virology, November 2016, ASM Journals

    Professor Ling Zhao

  91. Recombinant rabies virus expressing IL-21 enhances immunogenicity through activation of T follicular helper cells and germinal center B cells

    Article • Journal of General Virology, October 2016, Society for General Microbiology

    Professor Ling Zhao

  92. Comparison of the immunogenicity of two inactivated recombinant rabies viruses overexpressing the glycoprotein

    Article • Archives of Virology, July 2016, Springer Science + Business Media

    Professor Ling Zhao

  93. Structural basis for the dimerization and substrate recognition specificity of porcine epidemic diarrhea virus 3C-like protease

    Article • Virology, July 2016, Elsevier

    Professor Ling Zhao

  94. Crystal structure of the mouse hepatitis virus ns2 phosphodiesterase domain that antagonizes RNase L activation

    Article • Journal of General Virology, April 2016, Society for General Microbiology

    Professor Ling Zhao

  95. Rabies virus phosphoprotein interacts with ribosomal protein L9 and affects rabies virus replication

    Article • Virology, January 2016, Elsevier

    Professor Ling Zhao

  96. Critical Role of K1685 and K1829 in the Large Protein of Rabies Virus in Viral Pathogenicity and Immune Evasion

    Article • Journal of Virology, October 2015, ASM Journals

    Dr Zhen F Fu, Professor Ling Zhao

  97. λ-Carrageenan P32 Is a Potent Inhibitor of Rabies Virus Infection

    Article • PLoS ONE, October 2015, PLOS

    Professor Ling Zhao

  98. Recombinant rabies virus expressing dog GM-CSF is an efficacious oral rabies vaccine for dogs

    Article • Oncotarget, October 2015, Impact Journals, LLC

    Professor Ling Zhao

  99. Comparison of complete genome sequences of dog rabies viruses isolated from China and Mexico reveals key amino acid changes that may be associated with virus replication and virulence

    Article • Archives of Virology, January 2014, Springer Science + Business Media

    Professor Ling Zhao

  100. 244

    Article • Cytokine, September 2013, Elsevier

    Professor Ling Zhao

  101. Homologous 2′,5′-phosphodiesterases from disparate RNA viruses antagonize antiviral innate immunity

    Article • Proceedings of the National Academy of Sciences, July 2013, Proceedings of the National Academy of Sciences

    Professor Ling Zhao

  102. Cell-Type-Specific Activation of the Oligoadenylate Synthetase-RNase L Pathway by a Murine Coronavirus

    Article • Journal of Virology, May 2013, ASM Journals

    Dr Susan R Weiss, Professor Ling Zhao

  103. O030 Evasion of the OAS-RNase L pathway by murine coronavirus ns2 protein is required for viral replication and hepatitis

    Article • Cytokine, September 2012, Elsevier

    Professor Ling Zhao

  104. Antagonism of the Interferon-Induced OAS-RNase L Pathway by Murine Coronavirus ns2 Protein Is Required for Virus Replication and Liver Pathology

    Article • Cell Host & Microbe, June 2012, Elsevier

    Dr Susan R Weiss, Professor Ling Zhao

  105. Cell-Type-Specific Type I Interferon Antagonism Influences Organ Tropism of Murine Coronavirus

    Article • Journal of Virology, July 2011, ASM Journals

    Professor Ling Zhao

  106. Expression of MIP-1α (CCL3) by a Recombinant Rabies Virus Enhances Its Immunogenicity by Inducing Innate Immunity and Recruiting Dendritic Cells and B Cells

    Article • Journal of Virology, June 2010, ASM Journals

    Professor Ling Zhao

  107. The Roles of Chemokines in Rabies Virus Infection: Overexpression May Not Always Be Beneficial

    Article • Journal of Virology, September 2009, ASM Journals

    Professor Ling Zhao

  108. Role of chemokines in the enhancement of BBB permeability and inflammatory infiltration after rabies virus infection

    Article • Virus Research, September 2009, Elsevier

    Professor Ling Zhao

  109. Faculty of 1000 evaluation for Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5.

    Article • Faculty of 1000, Ltd.

    Professor Ling Zhao

  110. Faculty of 1000 evaluation for Plasmacytoid dendritic cells control T-cell response to chronic viral infection.

    Article • Faculty of 1000, Ltd.

    Professor Ling Zhao