All Stories

  1. Activation of sterol regulatory element-binding protein 1 (SREBP1)-mediated lipogenesis by the Epstein-Barr virus-encoded latent membrane protein 1 (LMP1) promotes cell proliferation and progression of nasopharyngeal carcinoma

    Article • The Journal of Pathology, August 2018, Wiley

    Lawrence Young

  2. The Dynamic Roles of TGF-β Signalling in EBV-Associated Cancers

    Article • Cancers, July 2018, MDPI AG

    Lawrence Young

  3. The EBV-Encoded Oncoprotein, LMP1, Induces an Epithelial-to-Mesenchymal Transition (EMT) via Its CTAR1 Domain through Integrin-Mediated ERK-MAPK Signalling

    Article • Cancers, May 2018, MDPI AG

    Lawrence Young

  4. Epstein–Barr virus: more than 50 years old and still providing surprises

    Article • Nature Reviews Drug Discovery, September 2016, Springer Science + Business Media

    Lawrence Young

  5. Erratum: Epstein-Barr virus and carcinomas: rare association of the virus with gastric adenocarcinomas

    Article • British Journal of Cancer, May 2016, Springer Science + Business Media

    Lawrence Young

  6. The Epstein-Barr virus encoded LMP1 oncoprotein modulates cell adhesion via regulation of activin A/TGFβ and β1 integrin signalling

    Article • Scientific Reports, January 2016, Springer Science + Business Media

    Lawrence Young

  7. Activation of the FGFR1 signalling pathway by the Epstein-Barr virus-encoded LMP1 promotes aerobic glycolysis and transformation of human nasopharyngeal epithelial cells

    Article • The Journal of Pathology, August 2015, Wiley

    Lawrence Young

  8. Genome Diversity of Epstein-Barr Virus from Multiple Tumor Types and Normal Infection

    Article • Journal of Virology, March 2015, ASM Journals

    Dr Matthew L Cotten, Lawrence Young

  9. Epstein-Barr virus and nasopharyngeal carcinoma

    Article • Chinese Journal of Cancer, November 2014, Editorial Office of Chinese Journal of Cancer

    Lawrence Young

  10. Epstein-Barr virus at 50-future perspectives

    Article • Chinese Journal of Cancer, November 2014, Editorial Office of Chinese Journal of Cancer

    Lawrence Young

  11. Fas-associated factor (Faf1) is a novel CD40 interactor that regulates CD40-induced NF-κB activation via a negative feedback loop

    Article • Cell Death and Disease, May 2014, Springer Science + Business Media

    Lawrence Young

  12. Epstein-Barr virus induction of the Hedgehog signalling pathway imposes a stem cell phenotype on human epithelial cells

    Article • The Journal of Pathology, October 2013, Wiley

    Lawrence Young

  13. Inhibition of the LKB1-AMPK pathway by the Epstein-Barr virus-encoded LMP1 promotes proliferation and transformation of human nasopharyngeal epithelial cells

    Article • The Journal of Pathology, June 2013, Wiley

    Lawrence Young

  14. A Global View of the Oncogenic Landscape in Nasopharyngeal Carcinoma: An Integrated Analysis at the Genetic and Expression Levels

    Article • PLoS ONE, July 2012, PLOS

    Lawrence Young

  15. Smoking initiation is followed by the early acquisition of epigenetic change in cervical epithelium: a longitudinal study

    Article • British Journal of Cancer, April 2011, Springer Science + Business Media

    Lawrence Young

  16. Phase I/II trial of a dendritic cell vaccine transfected with DNA encoding melan A and gp100 for patients with metastatic melanoma

    Article • Gene Therapy, February 2011, Springer Science + Business Media

    Lawrence Young

  17. Epstein–Barr virus and carcinogenesis: beyond Burkitt's lymphoma

    Article • Clinical Microbiology and Infection, November 2009, Elsevier

    Lawrence Young

  18. The EBV-encoded latent membrane proteins, LMP2A and LMP2B, limit the actions of interferon by targeting interferon receptors for degradation

    Article • Oncogene, August 2009, Springer Science + Business Media

    Lawrence Young

  19. The Epstein-Barr virus oncoprotein, latent membrane protein-1, reprograms germinal centre B cells towards a Hodgkin's Reed-Sternberg-like phenotype

    Article • The Journal of Pathology, September 2008, Wiley

    Lawrence Young

  20. Combining gene and immunotherapy for prostate cancer

    Article • Prostate Cancer and Prostatic Diseases, August 2007, Springer Science + Business Media

    Lawrence Young

  21. Epstein–Barr virus-encoded EBNA1 regulates cellular gene transcription and modulates the STAT1 and TGFβ signaling pathways

    Article • Oncogene, May 2007, Springer Science + Business Media

    Lawrence Young

  22. The natural history of cervical HPV infection: unresolved issues

    Article • Nature Reviews Drug Discovery, January 2007, Springer Science + Business Media

    Lawrence Young

  23. The polycomb group proteins, BMI-1 and EZH2, are tumour-associated antigens

    Article • British Journal of Cancer, October 2006, Springer Science + Business Media

    Lawrence Young

  24. Inhibition of NF-κB enhances the cytotoxicity of virus-directed enzyme prodrug therapy and oncolytic adenovirus cancer gene therapy

    Article • Gene Therapy, March 2005, Springer Science + Business Media

    Lawrence Young

  25. PTTG's C-terminal PXXP motifs modulate critical cellular processes in vitro

    Article • Journal of Molecular Endocrinology, December 2004, Bioscientifica

    Lawrence Young

  26. Epstein–Barr virus: 40 years on

    Article • Nature Reviews Drug Discovery, October 2004, Springer Science + Business Media

    Lawrence Young

  27. Enhanced efficacy of Escherichia coli nitroreductase/CB1954 prodrug activation gene therapy using an E1B-55K-deleted oncolytic adenovirus vector

    Article • Gene Therapy, May 2004, Springer Science + Business Media

    Lawrence Young

  28. An interferon-γ ELISPOT and immunohistochemical investigation of cytotoxic T lymphocyte-mediated tumour immunity in patients with paraneoplastic cerebellar degeneration and anti-Yo antibodies

    Article • Journal of Neuroimmunology, May 2004, Elsevier

    Lawrence Young

  29. Expression of the cellular FLICE-inhibitory protein (c-FLIP) protects Hodgkin's lymphoma cells from autonomous Fas-mediated death

    Article • Proceedings of the National Academy of Sciences, April 2004, Proceedings of the National Academy of Sciences

    Lawrence Young

  30. Epstein–Barr virus latent membrane protein 1 (LMP1) upregulates Id1 expression in nasopharyngeal epithelial cells

    Article • Oncogene, April 2004, Springer Science + Business Media

    Lawrence Young

  31. Seasonal differences in the onset of the EBV-positive and -negative forms of paediatric Hodgkin's lymphoma

    Article • British Journal of Cancer, September 2003, Springer Science + Business Media

    Lawrence Young

  32. Mechanism of cell death induced by the novel enzyme-prodrug combination, nitroreductase/CB1954 and identification of synergism with 5-fluorouracil

    Article • British Journal of Cancer, August 2003, Springer Science + Business Media

    Lawrence Young

  33. The effect of Epstein-Barr virus status on outcome in age- and sex-defined subgroups of patients with advanced Hodgkin's disease

    Article • Annals of Oncology, February 2003, Oxford University Press (OUP)

    Lawrence Young

  34. Induction of apoptosis by chemotherapeutic drugs: the role of FADD in activation of caspase-8 and synergy with death receptor ligands in ovarian carcinoma cells

    Article • Cell Death and Differentiation, March 2002, Springer Science + Business Media

    Lawrence Young

  35. LMP1 structure and signal transduction

    Article • Seminars in Cancer Biology, December 2001, Elsevier

    Lawrence Young

  36. Frequent expression of the tumor necrosis factor receptor–associated factor 1 in latent membrane protein 1–Positive posttransplant lymphoproliferative disease and HIV-associated lymphomas

    Article • Human Pathology, September 2001, Elsevier

    Lawrence Young

  37. South Asian ethnicity and material deprivation increase the risk of Epstein-Barr virus infection in childhood Hodgkin's disease

    Article • British Journal of Cancer, July 2001, Springer Science + Business Media

    Lawrence Young

  38. Gene therapy for hepatocellular carcinoma—teaching old dogs new tricks

    Article • Hepatology, July 2001, Wiley

    Lawrence Young

  39. Identification of Functional Differences between Prototype Epstein–Barr Virus-Encoded LMP1 and a Nasopharyngeal Carcinoma-Derived LMP1 in Human Epithelial Cells

    Article • Virology, June 2000, Elsevier

    Lawrence Young

  40. Epstein-Barr virus: Biology and disease

    Article • Oral Diseases, May 1997, Wiley

    Lawrence Young