All Stories

  1. Quantification of cardiac pumping mechanics in rats by using the elastance–resistance model based solely on the measured left ventricular pressure and cardiac output

    Article • Pflügers Archiv - European Journal of Physiology, March 2019, Springer Science + Business Media

    Professor Kuo-Chu Chang

  2. Quantification of contractile mechanics in the rat heart from ventricular pressure alone

    Article • Oncotarget, October 2017, Impact Journals, LLC

    Professor Kuo-Chu Chang

  3. Defects in Vascular Mechanics Due to Aging in Rats: Studies on Arterial Wave Properties from a Single Aortic Pressure Pulse

    Article • Frontiers in Physiology, July 2017, Frontiers

    Professor Kuo-Chu Chang

  4. Determining arterial wave transit time from a single aortic pressure pulse in rats: vascular impulse response analysis

    Article • Scientific Reports, January 2017, Nature

    Professor Kuo-Chu Chang

  5. Systolic aortic pressure-time area is a useful index describing arterial wave properties in rats with diabetes

    Article • Scientific Reports, December 2015, Nature

    Professor Kuo-Chu Chang

  6. Methylprednisolone Protects Cardiac Pumping Mechanics from Deteriorating in Lipopolysaccharide-Treated Rats

    Article • Frontiers in Physiology, November 2015, Frontiers

    Professor Kuo-Chu Chang

  7. Pyridoxamine protects against mechanical defects in cardiac ageing in rats: studies on load dependence of myocardial relaxation

    Article • Quarterly Journal of Experimental Physiology and Cognate Medical Sciences, October 2014, Wiley

    Professor Kuo-Chu Chang

  8. Prevention of Arterial Stiffening by Using Low-Dose Atorvastatin in Diabetes Is Associated with Decreased Malondialdehyde

    Article • PLoS ONE, March 2014, PLOS

    Professor Kuo-Chu Chang

  9. Acetyl-l-Carnitine and Oxfenicine on Cardiac Pumping Mechanics in Streptozotocin-Induced Diabetes in Male Wistar Rats

    Article • PLoS ONE, July 2013, PLOS

    Professor Kuo-Chu Chang

  10. Methylprednisolone Stiffens Aortas in Lipopolysaccharide-Induced Chronic Inflammation in Rats

    Article • PLoS ONE, July 2013, PLOS

    Professor Kuo-Chu Chang

  11. Research update for articles published in EJCI in 2010

    Article • European Journal of Clinical Investigation, October 2012, Wiley

    Dr Alberto Bouzas-Mosquera, Dr Sona B Nair, Professor Kuo-Chu Chang

  12. Early return of augmented wave reflection impairs left ventricular relaxation in aged Fisher 344 rats

    Article • Experimental Gerontology, September 2012, Elsevier

    Professor Kuo-Chu Chang

  13. Enhanced Aortic Nerve Growth Factor Expression and Nerve Sprouting in Rats Following Gastric Perforation

    Article • Journal of Surgical Research, November 2011, Elsevier

    Professor Kuo-Chu Chang

  14. Pyridoxamine prevents age-related aortic stiffening and vascular resistance in association with reduced collagen glycation

    Article • Experimental Gerontology, June 2011, Elsevier

    Professor Kuo-Chu Chang

  15. Effects of acetyl-L-carnitine and oxfenicine on aorta stiffness in diabetic rats

    Article • European Journal of Clinical Investigation, July 2010, Wiley

    Professor Kuo-Chu Chang

  16. ENHANCED EXPRESSION OF CARDIAC NERVE GROWTH FACTOR AND NERVE SPROUTING MARKERS IN RATS FOLLOWING GASTRIC PERFORATION

    Article • Shock, February 2010, Wolters Kluwer Health

    Professor Kuo-Chu Chang

  17. Prevention of arterial stiffening by pyridoxamine in diabetes is associated with inhibition of the pathogenic glycation on aortic collagen

    Article • British Journal of Pharmacology, August 2009, Wiley

    Professor Kuo-Chu Chang

  18. Autonomic neuropathy precedes cardiovascular dysfunction in rats with diabetes

    Article • European Journal of Clinical Investigation, September 2008, Wiley

    Professor Kuo-Chu Chang

  19. Aminoguanidine prevents the impairment of cardiac pumping mechanics in rats with streptozotocin and nicotinamide-induced type 2 diabetes

    Article • British Journal of Pharmacology, June 2008, Wiley

    Professor Kuo-Chu Chang

  20. Aminoguanidine prevents fructose-induced deterioration in left ventricular-arterial coupling in Wistar rats

    Article • British Journal of Pharmacology, June 2007, Wiley

    Professor Kuo-Chu Chang

  21. Aminoguanidine prevents arterial stiffening in a new rat model of type 2 diabetes

    Article • European Journal of Clinical Investigation, August 2006, Wiley

    Professor Kuo-Chu Chang

  22. Aminoguanidine prevents arterial stiffening and cardiac hypertrophy in streptozotocin-induced diabetes in rats

    Article • British Journal of Pharmacology, April 2006, Wiley

    Professor Kuo-Chu Chang

  23. Arterial stiffening and cardiac hypertrophy in a new rat model of type 2 diabetes

    Article • European Journal of Clinical Investigation, January 2006, Wiley

    Professor Kuo-Chu Chang

  24. Aminoguanidine prevents age-related deterioration in left ventricular-arterial coupling in Fisher 344 rats

    Article • British Journal of Pharmacology, August 2004, Wiley

    Professor Kuo-Chu Chang

  25. Aminoguanidine prevents age-related aortic stiffening in Fisher 344 rats: aortic impedance analysis

    Article • British Journal of Pharmacology, September 2003, Wiley

    Professor Kuo-Chu Chang

  26. Mechanical effects of liriodenine on the left ventricular-arterial coupling in Wistar rats: pressure-stroke volume analysis

    Article • British Journal of Pharmacology, May 2001, Wiley

    Professor Kuo-Chu Chang

  27. Article • Biogerontology, January 2001, Springer Science + Business Media

    Professor Kuo-Chu Chang

  28. Impaired Vascular Dynamics in Normotensive Diabetic Rats Induced by Streptozotocin: Tapered T-tube Model Analysis

    Article • Journal of Theoretical Biology, June 2000, Elsevier

    Professor Kuo-Chu Chang

  29. Acute effects of methoxamine on left ventricular-arterial coupling in streptozotocin-diabetic rats: a pressure-volume analysis

    Article • Canadian Journal of Physiology and Pharmacology, January 2000, Canadian Science Publishing

    Professor Kuo-Chu Chang

  30. Theoretical Maximal Flow of the Left Ventricle is Sensitive to Change in Ventricular Afterload

    Article • Journal of Theoretical Biology, October 1998, Elsevier

    Professor Kuo-Chu Chang

  31. Hypertensive effects of methoxamine on arterial mechanics in rats: analysis based on exponentially tapered T-tube model

    Article • European Journal of Pharmacology, June 1998, Elsevier

    Professor Kuo-Chu Chang

  32. Acute effects of nitric oxide blockade with L -NAME on arterial haemodynamics in the rat

    Article • British Journal of Pharmacology, November 1997, Wiley

    Professor Kuo-Chu Chang

  33. Single-beat Estimation of the Ventricular Pumping Mechanics in Terms of the Systolic Elastance and Resistance

    Article • Journal of Theoretical Biology, November 1997, Elsevier

    Professor Kuo-Chu Chang

  34. Exponentially Tapered T-tube Model in the Characterization of Arterial Non-uniformity

    Article • Journal of Theoretical Biology, November 1996, Elsevier

    Professor Kuo-Chu Chang

  35. Reply to Professor Burattini's comments on “Exponentially tapered t-tube model of systemic arterial system in dogs”

    Article • Medical Engineering & Physics, June 1996, Elsevier

    Professor Kuo-Chu Chang

  36. Impedance and wave reflection in arterial system: simulation with geometrically tapered T-tubes

    Article • Medical & Biological Engineering & Computing, September 1995, Springer Science + Business Media

    Professor Kuo-Chu Chang

  37. Exponentially tapered t-tube model of systemic arterial system in dogs

    Article • Medical Engineering & Physics, September 1994, Elsevier

    Professor Kuo-Chu Chang

  38. The correlation of cardiac mass with arterial haemodynamics of resistive and capacitive load in rats with normotension and established hypertension

    Article • Pflügers Archiv - European Journal of Physiology, January 1994, Springer Science + Business Media

    Professor Kuo-Chu Chang

  39. Acute adaptation and resetting of the baroreflex control of vascular resistance in the canine hindquarters and mesentery

    Article • Pflügers Archiv - European Journal of Physiology, August 1993, Springer Science + Business Media

    Professor Kuo-Chu Chang

  40. Prediction of arterial input impedance spectrum by an asymmetric T-tube model terminated with an opportune complex load

    Article • Journal of the Chinese Institute of Engineers, July 1992, Taylor & Francis

    Professor Kuo-Chu Chang

  41. Assessment of Threshold and Saturation Pressure in the Baroreflex Function Curve:A New Mathematical Analysis.

    Article • The Japanese Journal of Physiology, January 1991, Physiological Society of Japan

    Professor Kuo-Chu Chang