All Stories

  1. Mettl1-dependent m7G tRNA modification is essential for maintaining spermatogenesis and fertility in Drosophila melanogaster

    Article • Nature Communications, September 2024, Springer Science + Business Media

    Professor Kei-ichiro Ishiguro

  2. Female‐specific mechanisms of meiotic initiation and progression in mammalian oocyte development

    Article • Genes to Cells, August 2024, Wiley

    Professor Kei-ichiro Ishiguro

  3. Mechanisms of meiosis initiation and meiotic prophase progression during spermatogenesis

    Article • Molecular Aspects of Medicine, June 2024, Elsevier

    Professor Kei-ichiro Ishiguro

  4. ZSCAN4-binding motif—TGCACAC is conserved and enriched in CA/TG microsatellites in both mouse and human genomes

    Article • DNA Research, December 2023, Oxford University Press (OUP)

    Professor Kei-ichiro Ishiguro

  5. STRA8–RB interaction is required for timely entry of meiosis in mouse female germ cells

    Article • Nature Communications, October 2023, Springer Science + Business Media

    Professor Kei-ichiro Ishiguro

  6. HMGA2 directly mediates chromatin condensation in association with neuronal fate regulation

    Article • Nature Communications, October 2023, Springer Science + Business Media

    Professor Kei-ichiro Ishiguro

  7. The role of Zfp352 in the regulation of transient expression of 2‐cell specific genes in mouse embryonic stem cells

    Article • Genes to Cells, October 2023, Wiley

    Professor Kei-ichiro Ishiguro

  8. Atypical heat shock transcription factor HSF5 is critical for male meiotic prophase under non-stress conditions

    Article • September 2023, Cold Spring Harbor Laboratory Press

    Professor Kei-ichiro Ishiguro

  9. Age‐associated reduction of nuclear shape dynamics in excitatory neurons of the visual cortex

    Article • Aging Cell, July 2023, Wiley

    Professor Kei-ichiro Ishiguro

  10. Conserved H3K27me3-associated chromatin remodelling allows STRA8 but not MEIOSIN expression in mammalian germ cells

    Article • Reproduction, March 2023, Bioscientifica

    Professor Kei-ichiro Ishiguro

  11. Active DNA damage response signaling initiates and maintains meiotic sex chromosome inactivation

    Article • Nature Communications, November 2022, Springer Science + Business Media

    Professor Kei-ichiro Ishiguro

  12. Switching defective/sucrose non‐fermenting chromatin remodeling complex coordinates meiotic gene activation via promoter remodeling and Meiosin activation in female germline

    Article • Genes to Cells, November 2022, Wiley

    Professor Kei-ichiro Ishiguro

  13. Unlocking the mystery of glucose detection: How the polyol pathway keeps our bodies balanced

    Article • PLoS Biology, June 2022, PLOS

    Hiroko Sano, Professor Kei-ichiro Ishiguro

  14. Trim41 is required to regulate chromosome axis protein dynamics and meiosis in male mice

    Article • PLoS Genetics, June 2022, PLOS

    masahito ikawa, Professor Kei-ichiro Ishiguro

  15. Tandem immuno-purification of affinity-tagged proteins from mouse testis extracts for MS analysis

    Article • STAR Protocols, June 2022, Elsevier

    Professor Kei-ichiro Ishiguro

  16. Temperature sensitivity of DNA double-strand break repair underpins heat-induced meiotic failure in mouse spermatogenesis

    Article • Communications Biology, May 2022, Springer Science + Business Media

    Professor Kei-ichiro Ishiguro

  17. Map7D2 and Map7D1 facilitate microtubule stabilization through distinct mechanisms in neuronal cells

    Article • Life Science Alliance, April 2022, Life Science Alliance, LLC

    Professor Kei-ichiro Ishiguro

  18. MCMBP promotes the assembly of the MCM2–7 hetero-hexamer to ensure robust DNA replication in human cells

    Article • eLife, April 2022, eLife

    Professor Kei-ichiro Ishiguro

  19. FBXO47 is essential for preventing the synaptonemal complex from premature disassembly in mouse male meiosis

    Article • iScience, April 2022, Elsevier

    Professor Kei-ichiro Ishiguro

  20. MCMBP promotes the assembly of the MCM2-7 hetero-hexamer to ensure robust DNA replication in human cells

    Article • February 2022, Cold Spring Harbor Laboratory Press

    Professor Kei-ichiro Ishiguro

  21. MEIOSIN directs initiation of meiosis and subsequent meiotic prophase program during spermatogenesis

    Article • Genes & Genetic Systems, February 2022, Genetics Society of Japan

    Professor Kei-ichiro Ishiguro

  22. Sexually Dimorphic Properties in Meiotic Chromosome

    Article • Sexual Development, January 2022, Karger Publishers

    Professor Kei-ichiro Ishiguro

  23. FBXO47 is essential for preventing the synaptonemal complex from premature disassembly in mouse male meiosis

    Article • November 2021, Cold Spring Harbor Laboratory Press

    Professor Kei-ichiro Ishiguro

  24. Trim41 is essential for preventing X chromosome chaotic synapsis in male mice

    Article • November 2021, Cold Spring Harbor Laboratory Press

    Professor Kei-ichiro Ishiguro

  25. Map7D2 and Map7D1 facilitate microtubule stabilization through distinct mechanisms in neuronal cells

    Article • October 2021, Cold Spring Harbor Laboratory Press

    Professor Kei-ichiro Ishiguro

  26. The polyol pathway is an evolutionarily conserved system for sensing glucose uptake

    Article • September 2021, Cold Spring Harbor Laboratory Press

    Professor Kei-ichiro Ishiguro

  27. Gene trapping reveals a new transcriptionally active genome element: The chromosome‐specific clustered trap region

    Article • Genes to Cells, August 2021, Wiley

    Professor Kei-ichiro Ishiguro

  28. KCTD19 and its associated protein ZFP541 are independently essential for meiosis in male mice

    Article • PLoS Genetics, May 2021, PLOS

    masahito ikawa, Professor Kei-ichiro Ishiguro

  29. Sycp1 Is Not Required for Subtelomeric DNA Double-Strand Breaks but Is Required for Homologous Alignment in Zebrafish Spermatocytes

    Article • Frontiers in Cell and Developmental Biology, March 2021, Frontiers

    Professor Kei-ichiro Ishiguro

  30. KCTD19 associates with ZFP541 and HDAC1 and is required for meiotic exit in male mice

    Article • February 2021, Cold Spring Harbor Laboratory Press

    Professor Kei-ichiro Ishiguro

  31. Meiosis-specific ZFP541 repressor complex promotes meiotic prophase exit during spermatogenesis

    Article • January 2021, Cold Spring Harbor Laboratory Press

    Professor Kei-ichiro Ishiguro

  32. Meiotic cohesins mediate initial loading of HORMAD1 to the chromosomes and coordinate SC formation during meiotic prophase

    Article • PLoS Genetics, September 2020, PLOS

    Professor Kei-ichiro Ishiguro

  33. Phosphorylation of the Anaphase Promoting Complex activator CDH1/FZR regulates the transition from Meiosis I to Meiosis II in mouse male germ cell

    Article • March 2020, Cold Spring Harbor Laboratory Press

    Professor Kei-ichiro Ishiguro

  34. Sycp2 is essential for synaptonemal complex assembly, early meiotic recombination and homologous pairing in zebrafish spermatocytes

    Article • PLoS Genetics, February 2020, PLOS

    Professor Kei-ichiro Ishiguro

  35. A meiosis-specific factor C19orf57/4930432K21Rik/BRME1 modulates localization of RAD51 and DMC1 recombinases to DSBs in mouse meiotic recombination

    Article • February 2020, Cold Spring Harbor Laboratory Press

    Professor Kei-ichiro Ishiguro

  36. MEIOSIN Directs the Switch from Mitosis to Meiosis in Mammalian Germ Cells

    Article • Developmental Cell, February 2020, Elsevier

    Professor Kei-ichiro Ishiguro

  37. Induction of human pluripotent stem cells into kidney tissues by synthetic mRNAs encoding transcription factors

    Article • Scientific Reports, January 2019, Springer Science + Business Media

    Professor Kei-ichiro Ishiguro

  38. The cohesin complex in mammalian meiosis

    Article • Genes to Cells, November 2018, Wiley

    Professor Kei-ichiro Ishiguro

  39. Establishment of a rapid and footprint-free protocol for differentiation of human embryonic stem cells into pancreatic endocrine cells with synthetic mRNAs encoding transcription factors

    Article • Stem Cell Research & Therapy, October 2018, Springer Science + Business Media

    Professor Kei-ichiro Ishiguro

  40. Author Correction: Meikin is a conserved regulator of meiosis-I-specific kinetochore function

    Article • Nature, October 2018, Springer Science + Business Media

    Professor Kei-ichiro Ishiguro

  41. Zscan4 is expressed specifically during late meiotic prophase in both spermatogenesis and oogenesis

    Article • In Vitro Cellular & Developmental Biology - Animal, October 2016, Springer Science + Business Media

    Prof Manuela Monti, Professor Kei-ichiro Ishiguro

  42. Expression analysis of the endogenous Zscan4 locus and its coding proteins in mouse ES cells and preimplantation embryos

    Article • In Vitro Cellular & Developmental Biology - Animal, October 2016, Springer Science + Business Media

    Professor Kei-ichiro Ishiguro

  43. The cohesin REC 8 prevents illegitimate inter‐sister synaptonemal complex assembly

    Article • EMBO Reports, May 2016, EMBO

    Professor Kei-ichiro Ishiguro

  44. MEI4: a central player in the regulation of meiotic DNA double strand break formation in the mouse

    Article • Journal of Cell Science, January 2015, The Company of Biologists

    Professor Kei-ichiro Ishiguro

  45. Meikin is a conserved regulator of meiosis-I-specific kinetochore function

    Article • Nature, December 2014, Springer Science + Business Media

    Professor Kei-ichiro Ishiguro

  46. p600 regulates spindle orientation in apical neural progenitors and contributes to neurogenesis in the developing neocortex

    Article • Biology Open, May 2014, The Company of Biologists

    Professor Kei-ichiro Ishiguro

  47. Meiosis-specific cohesin mediates homolog recognition in mouse spermatocytes

    Article • Genes & Development, March 2014, Cold Spring Harbor Laboratory Press

    Professor Kei-ichiro Ishiguro

  48. The TRF1-binding protein TERB1 promotes chromosome movement and telomere rigidity in meiosis

    Article • Nature Cell Biology, January 2014, Springer Science + Business Media

    Professor Kei-ichiro Ishiguro

  49. p600 Plays Essential Roles in Fetal Development

    Article • PLoS ONE, June 2013, PLOS

    Professor Kei-ichiro Ishiguro

  50. A conserved KASH domain protein associates with telomeres, SUN1, and dynactin during mammalian meiosis

    Article • The Journal of Cell Biology, July 2012, Rockefeller University Press

    Professor Kei-ichiro Ishiguro

  51. A new meiosis‐specific cohesin complex implicated in the cohesin code for homologous pairing

    Article • EMBO Reports, January 2011, EMBO

    Professor Kei-ichiro Ishiguro

  52. Phosphorylation of mammalian Sgo2 by Aurora B recruits PP2A and MCAK to centromeres

    Article • Genes & Development, October 2010, Cold Spring Harbor Laboratory Press

    Professor Kei-ichiro Ishiguro

  53. Phosphorylation of H2A by Bub1 Prevents Chromosomal Instability Through Localizing Shugoshin

    Article • Science, January 2010, American Association for the Advancement of Science

    Professor Kei-ichiro Ishiguro

  54. Protein 600 Is a Microtubule/Endoplasmic Reticulum-Associated Protein in CNS Neurons

    Article • Journal of Neuroscience, April 2008, Society for Neuroscience

    Professor Kei-ichiro Ishiguro

  55. Chromosome cohesion in mitosis and meiosis

    Article • Journal of Cell Science, February 2007, The Company of Biologists

    Professor Kei-ichiro Ishiguro

  56. Shugoshin collaborates with protein phosphatase 2A to protect cohesin

    Article • Nature, March 2006, Springer Science + Business Media

    Professor Kei-ichiro Ishiguro

  57. Correction

    Article • Proceedings of the National Academy of Sciences, December 2005, Proceedings of the National Academy of Sciences

    Professor Kei-ichiro Ishiguro

  58. p600, a unique protein required for membrane morphogenesis and cell survival

    Article • Proceedings of the National Academy of Sciences, October 2005, Proceedings of the National Academy of Sciences

    Professor Kei-ichiro Ishiguro

  59. Footprint Analysis of Recombination Signal Sequences in the 12/23 Synaptic Complex of V(D)J Recombination

    Article • Molecular and Cellular Biology, October 2002, ASM Journals

    Professor Kei-ichiro Ishiguro

  60. A Complex with Chromatin Modifiers That Occupies E2F- and Myc-Responsive Genes in G0Cells

    Article • Science, May 2002, American Association for the Advancement of Science

    Professor Kei-ichiro Ishiguro

  61. The DNA-bending protein, HMG1, is required for correct cleavage of 23 bp recombination signal sequences by recombination activating gene proteins in vitro

    Article • International Immunology, May 2000, Oxford University Press (OUP)

    Professor Kei-ichiro Ishiguro

  62. Footprint Analysis of the RAG Protein Recombination Signal Sequence Complex for V(D)J Type Recombination

    Article • Molecular and Cellular Biology, January 1998, ASM Journals

    Professor Kei-ichiro Ishiguro