All Stories

  1. The LIV-1 Subfamily of Zinc Transporters: From Origins to Present Day Discoveries

    Article • International Journal of Molecular Sciences, January 2023, MDPI AG

    Dr Kathryn M Taylor

  2. The importance of targeting signalling mechanisms of the SLC39A family of zinc transporters to inhibit endocrine resistant breast cancer

    Article • Exploration of Targeted Anti-tumor Therapy, April 2022, Open Exploration Publishing

    Dr Kathryn M Taylor

  3. Zinc transporters and their functional integration in mammalian cells

    Article • Journal of Biological Chemistry, January 2021, Elsevier

    Dr Kathryn M Taylor

  4. The ZIP6/ZIP10 heteromer is essential for the zinc-mediated trigger of mitosis

    Article • Cellular and Molecular Life Sciences, August 2020, Springer Science + Business Media

    Dr Kathryn M Taylor

  5. Detailed analyses of the crucial functions of Zn transporter proteins in alkaline phosphatase activation

    Article • Journal of Biological Chemistry, April 2020, Elsevier

    Dr Kathryn M Taylor

  6. Activated zinc transporter ZIP7 as an indicator of anti-hormone resistance in breast cancer

    Article • Metallomics, September 2019, Oxford University Press (OUP)

    Dr Kathryn M Taylor

  7. ZnR/GPR39 upregulation of K+/Cl−-cotransporter 3 in tamoxifen resistant breast cancer cells

    Article • Cell Calcium, July 2019, Elsevier

    Dr Kathryn M Taylor

  8. B cell activation and proliferation increase intracellular zinc levels

    Article • The Journal of Nutritional Biochemistry, February 2019, Elsevier

    Dr Kathryn M Taylor

  9. Post-translational Mechanisms of Zinc Signalling in Cancer

    Article • January 2019, Springer Science + Business Media

    Dr Kathryn M Taylor

  10. Enhanced ZnR/GPR39 Activity in Breast Cancer, an Alternative Trigger of Signaling Leading to Cell Growth

    Article • Scientific Reports, May 2018, Springer Science + Business Media

    Dr Kathryn M Taylor

  11. Hyperglycemia-Induced Changes in ZIP7 and ZnT7 Expression Cause Zn 2+ Release From the Sarco(endo)plasmic Reticulum and Mediate ER Stress in the Heart

    Article • Diabetes, February 2017, American Diabetes Association

    Dr Kathryn M Taylor

  12. Phosphorylation of zinc channel ZIP7 drives MAPK, PI3K and mTOR growth and proliferation signalling

    Article • Metallomics, January 2017, Oxford University Press (OUP)

    Dr Kathryn M Taylor, Thirayost Nimmanon

  13. Posttranslational Mechanisms of Zinc Signaling

    Article • January 2017, Elsevier

    Dr Kathryn M Taylor, Thirayost Nimmanon

  14. Zinc transporter ZIP10 forms a heteromer with ZIP6 which regulates embryonic development and cell migration

    Article • Biochemical Journal, June 2016, Portland Press Ltd.

    Dr Kathryn M Taylor, Thirayost Nimmanon

  15. Monitoring cytosolic and ER Zn2+ in stimulated breast cancer cells using genetically encoded FRET sensors

    Article • Metallomics, January 2016, Oxford University Press (OUP)

    Dr Kathryn M Taylor

  16. eZinCh-2: A Versatile, Genetically Encoded FRET Sensor for Cytosolic and Intraorganelle Zn2+ Imaging

    Article • ACS Chemical Biology, July 2015, American Chemical Society (ACS)

    Dr Kathryn M Taylor

  17. Characterization of Zinc Influx Transporters (ZIPs) in Pancreatic β Cells

    Article • Journal of Biological Chemistry, May 2015, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Kathryn M Taylor

  18. Disulfiram-induced cytotoxicity and endo-lysosomal sequestration of zinc in breast cancer cells

    Article • Biochemical Pharmacology, February 2015, Elsevier

    Dr Kathryn M Taylor

  19. Cellular Zinc Signalling Is Triggered by CK2

    Article • January 2015, Springer Science + Business Media

    Dr Kathryn M Taylor, Thirayost Nimmanon

  20. Zinc Signaling and Cancer

    Article • January 2014, Springer Science + Business Media

    Dr Kathryn M Taylor, Thirayost Nimmanon

  21. A mechanism for epithelial–mesenchymal transition and anoikis resistance in breast cancer triggered by zinc channel ZIP6 and STAT3 (signal transducer and activator of transcription 3)

    Article • Biochemical Journal, October 2013, Portland Press Ltd.

    Dr Kathryn M Taylor

  22. Protein kinase CK2 opens the gate for zinc signaling

    Article • Cell Cycle, May 2012, Taylor & Francis

    Dr Kathryn M Taylor

  23. Protein Kinase CK2 Triggers Cytosolic Zinc Signaling Pathways by Phosphorylation of Zinc Channel ZIP7

    Article • Science Signaling, February 2012, American Association for the Advancement of Science

    Dr Kathryn M Taylor

  24. Differential Subcellular Localization of the Splice Variants of the Zinc Transporter ZnT5 Is Dictated by the Different C-Terminal Regions

    Article • PLoS ONE, August 2011, PLOS

    Dr Kathryn M Taylor

  25. Zip4 (Slc39a4) Expression is Activated in Hepatocellular Carcinomas and Functions to Repress Apoptosis, Enhance Cell Cycle and Increase Migration

    Article • PLoS ONE, October 2010, PLOS

    Dr Kathryn M Taylor

  26. Identification of LIV1, a Putative Zinc Transporter Gene Responsible for HDACi-Induced Apoptosis, Using a Functional Gene Screen Approach

    Article • Molecular Cancer Therapeutics, November 2009, American Association for Cancer Research (AACR)

    Dr Kathryn M Taylor

  27. Growth of hormone-dependent MCF-7 breast cancer cells is promoted by constitutive caveolin-1 whose expression is lost in an EGF-R-mediated manner during development of tamoxifen resistance

    Article • Breast Cancer Research and Treatment, March 2009, Springer Science + Business Media

    Dr Kathryn M Taylor

  28. Zinc transporters and cancer: a potential role for ZIP7 as a hub for tyrosine kinase activation

    Article • Trends in Molecular Medicine, March 2009, Elsevier

    Dr Kathryn M Taylor

  29. A distinct role in breast cancer for two LIV-1 family zinc transporters

    Article • Biochemical Society Transactions, December 2008, Portland Press Ltd.

    Dr Kathryn M Taylor

  30. ZIP7-Mediated Intracellular Zinc Transport Contributes to Aberrant Growth Factor Signaling in Antihormone-Resistant Breast Cancer Cells

    Article • Endocrinology, October 2008, Endocrine Society

    Dr Kathryn M Taylor

  31. Dual targeting of Src and ER prevents acquired antihormone resistance in breast cancer cells

    Article • Breast Cancer Research and Treatment, May 2008, Springer Science + Business Media

    Dr Kathryn M Taylor

  32. Zinc transporter HKE4 as a new target in antihormone resistance of breast cancer

    Article • May 2008, Springer Science + Business Media

    Dr Kathryn M Taylor

  33. LIV-1 suppression inhibits HeLa cell invasion by targeting ERK1/2-Snail/Slug pathway

    Article • Biochemical and Biophysical Research Communications, November 2007, Elsevier

    Dr Kathryn M Taylor

  34. Growth factor signalling in endocrine and anti-growth factor resistant breast cancer

    Article • Reviews in Endocrine and Metabolic Disorders, May 2007, Springer Science + Business Media

    Dr Kathryn M Taylor

  35. Article • Molecular Medicine, January 2007, The Feinstein Institute for Medical Research (North Shore LIJ Research Institute)

    Dr Kathryn M Taylor

  36. Fear of intimacy - a close LIV-1 acquaintancy?

    Article • Development, August 2006, The Company of Biologists

    Dr Kathryn M Taylor

  37. Tamoxifen resistance in MCF7 cells promotes EMT-like behaviour and involves modulation of β-catenin phosphorylation

    Article • International Journal of Cancer, January 2006, Wiley

    Dr Kathryn M Taylor

  38. Development of strategies for the use of anti-growth factor treatments

    Article • Endocrine Related Cancer, July 2005, Bioscientifica

    Dr Kathryn M Taylor, Prof Michele Rubini

  39. Structure-function analysis of a novel member of the LIV-1 subfamily of zinc transporters, ZIP14

    Article • FEBS Letters, December 2004, Wiley

    Dr Kathryn M Taylor

  40. Zinc transporter LIV-1: a link between cellular development and cancer progression

    Article • Trends in Endocrinology and Metabolism, December 2004, Elsevier

    Dr Kathryn M Taylor

  41. Structure-function analysis of HKE4, a member of the new LIV-1 subfamily of zinc transporters

    Article • Biochemical Journal, January 2004, Portland Press Ltd.

    Dr Kathryn M Taylor

  42. Structure–function analysis of LIV-1, the breast cancer-associated protein that belongs to a new subfamily of zinc transporters

    Article • Biochemical Journal, October 2003, Portland Press Ltd.

    Dr Kathryn M Taylor

  43. The LZT proteins; the LIV-1 subfamily of zinc transporters

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, April 2003, Elsevier

    Dr Kathryn M Taylor

  44. Imaging bioluminescent indicators shows Ca2+ and ATP permeability thresholds in live cells attacked by complement

    Article • Immunology, December 2001, Wiley

    Dr Kathryn M Taylor

  45. TENB2, a proteoglycan identified in prostate cancer that is associated with disease progression and androgen independence

    Article • International Journal of Cancer, January 2001, Wiley

    Dr Kathryn M Taylor

  46. LIV-1 Breast Cancer Protein Belongs to New Family of Histidine-Rich Membrane Proteins with Potential to Control Intracellular Zn 2+ Homeostasis

    Article • IUBMB Life, April 2000, Wiley

    Dr Kathryn M Taylor

  47. Cloning and Expression of the Bioluminescent Photoprotein Pholasin from the Bivalve Mollusc Pholas dactylus

    Article • Journal of Biological Chemistry, March 2000, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Kathryn M Taylor

  48. Mutation of recombinant complement component C9 reveals the significance of the N‐terminal region for polymerization

    Article • Immunology, May 1997, Wiley

    Dr Kathryn M Taylor

  49. A method for in vitro synthesis of unglycosylated recombinant complement component C9

    Article • Journal of Immunological Methods, January 1994, Elsevier

    Dr Kathryn M Taylor

  50. Development of tumor cell resistance to tumor necrosis factor cytolysis results in reduced fibronectin binding and altered ganglioside expression

    Article • Cytokine, May 1991, Elsevier

    Dr Kathryn M Taylor

  51. Experimental Endocrine Resistance: Concepts and Strategies

    Article • Springer Science + Business Media

    Dr Kathryn M Taylor