All Stories

  1. Pharmacokinetics and safety of oseltamivir in patients with end-stage renal disease treated with automated peritoneal dialysis

    Article • British Journal of Clinical Pharmacology, March 2015, Wiley

    Dr Kashyap Patel

  2. Modelling the time course of antimalarial parasite killing: a tour of animal and human models, translation and challenges

    Article • British Journal of Clinical Pharmacology, December 2014, Wiley

    Professor Kevin T Batty, Dr Kashyap Patel

  3. Comparison of the probability of target attainment of anidulafungin against Candida spp. in patients with acute leukaemia

    Article • International Journal of Antimicrobial Agents, November 2014, Elsevier

    Dr Kashyap Patel

  4. Predicting the parasite killing effect of artemisinin combination therapy in a murine malaria model

    Article • Journal of Antimicrobial Chemotherapy, April 2014, Oxford University Press (OUP)

    Dr Kashyap Patel

  5. Pulmonary and Systemic Pharmacokinetics of Inhaled and Intravenous Colistin Methanesulfonate in Cystic Fibrosis Patients: Targeting Advantage of Inhalational Administration

    Article • Antimicrobial Agents and Chemotherapy, February 2014, ASM Journals

    Dr Kashyap Patel, Professor Roger L Nation, Christopher Porter

  6. Population Pharmacokinetics of Colistin Methanesulfonate in Rats: Achieving Sustained Lung Concentrations of Colistin for Targeting Respiratory Infections

    Article • Antimicrobial Agents and Chemotherapy, August 2013, ASM Journals

    Dr Kashyap Patel, Christopher Porter

  7. The Role of Bystander Effects in the Antitumor Activity of the Hypoxia-Activated Prodrug PR-104

    Article • Frontiers in Oncology, January 2013, Frontiers

    Dr Kashyap Patel

  8. A Time-to-Event Pharmacodynamic Model Describing Treatment Response in Patients with Pulmonary Tuberculosis Using Days to Positivity in Automated Liquid Mycobacterial Culture

    Article • Antimicrobial Agents and Chemotherapy, November 2012, ASM Journals

    Dr Kashyap Patel

  9. Mechanism-Based Model of Parasite Growth and Dihydroartemisinin Pharmacodynamics in Murine Malaria

    Article • Antimicrobial Agents and Chemotherapy, November 2012, ASM Journals

    Dr Kashyap Patel

  10. Comparative pharmacokinetics and pharmacodynamics of urocortins 1, 2 and 3 in healthy sheep

    Article • British Journal of Pharmacology, June 2012, Wiley

    Dr Kashyap Patel

  11. Pharmacokinetic Concepts Revisited - Basic and Applied

    Article • Current Pharmaceutical Biotechnology, December 2011, Bentham Science Publishers

    Dr Kashyap Patel

  12. Population Pharmacokinetics of Fluconazole in Critically Ill Patients Receiving Continuous Venovenous Hemodiafiltration: Using Monte Carlo Simulations To Predict Doses for Specified Pharmacodynamic Targets

    Article • Antimicrobial Agents and Chemotherapy, September 2011, ASM Journals

    Dr Kashyap Patel

  13. PR-104 plus sorafenib in patients with advanced hepatocellular carcinoma

    Article • Cancer Chemotherapy and Pharmacology, May 2011, Springer Science + Business Media

    Dr Kashyap Patel

  14. Erratum to: Reductive metabolism of the dinitrobenzamide mustard anticancer prodrug PR-104 in mice

    Article • Cancer Chemotherapy and Pharmacology, March 2011, Springer Science + Business Media

    Dr Kashyap Patel

  15. A combined pharmacokinetic model for the hypoxia-targeted prodrug PR-104A in humans, dogs, rats and mice predicts species differences in clearance and toxicity

    Article • Cancer Chemotherapy and Pharmacology, August 2010, Springer Science + Business Media

    Dr Kashyap Patel

  16. Reductive metabolism of the dinitrobenzamide mustard anticancer prodrug PR-104 in mice

    Article • Cancer Chemotherapy and Pharmacology, May 2010, Springer Science + Business Media

    Dr Kashyap Patel

  17. Prediction of Tumour Tissue Diffusion Coefficients of Hypoxia-Activated Prodrugs from Physicochemical Parameters

    Article • Australian Journal of Chemistry, January 2008, CSIRO Publishing

    Dr Kashyap Patel

  18. Oxygen Dependence and Extravascular Transport of Hypoxia-Activated Prodrugs: Comparison of the Dinitrobenzamide Mustard PR-104A and Tirapazamine

    Article • International Journal of Radiation Oncology*Biology*Physics, October 2007, Elsevier

    Dr Kashyap Patel

  19. Analysis of the hypoxia-activated dinitrobenzamide mustard phosphate pre-prodrug PR-104 and its alcohol metabolite PR-104A in plasma and tissues by liquid chromatography–mass spectrometry

    Article • Journal of Chromatography B, September 2007, Elsevier

    Dr Kashyap Patel

  20. Mechanism of Action and Preclinical Antitumor Activity of the Novel Hypoxia-Activated DNA Cross-Linking Agent PR-104

    Article • Clinical Cancer Research, July 2007, American Association for Cancer Research (AACR)

    Dr Kashyap Patel

  21. 263 POSTER Metabolism and pharmacokinetics of PR-104, a hypoxia-activated nitrogen mustard prodrug in phase I clinical trial

    Article • European Journal of Cancer Supplements, November 2006, Elsevier

    Dr Kashyap Patel