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  1. Transgenic Overexpression of Myocilin Leads to Variable Ocular Anterior Segment and Retinal Alterations Associated with Extracellular Matrix Abnormalities in Adult Zebrafish

    Article • International Journal of Molecular Sciences, September 2022, MDPI AG

    Professor Julio Escribano

  2. Transgenic Overexpression of Myocilin Leads to Variable Ocular Anterior Segment and Retinal Alterations Associated with Extracellular Matrix Abnormalities in Adult Zebrafish

    Article • August 2022, MDPI AG

    Professor Julio Escribano

  3. RNA and protein expression analysis of HLA‐DQB1*03:01:01:21Q allele: A null allele renamed as HLA‐DQB1*03:01:01:21N ...

    Article • HLA, January 2022, Wiley

    Professor Julio Escribano

  4. Null cyp1b1 Activity in Zebrafish Leads to Variable Craniofacial Defects Associated with Altered Expression of Extracellular Matrix and Lipid Metabolism Genes

    Article • International Journal of Molecular Sciences, June 2021, MDPI AG

    Professor Julio Escribano

  5. Null cyp1b1 Activity in Zebrafish Leads to Variable Craniofacial Defects Associated with Altered Expression of Extracellular Matrix and Lipid Metabolism Genes

    Article • June 2021, MDPI AG

    Professor Julio Escribano

  6. Knockout of myoc Provides Evidence for the Role of Myocilin in Zebrafish Sex Determination Associated with Wnt Signalling Downregulation

    Article • Biology, January 2021, MDPI AG

    Professor Julio Escribano

  7. Knockout of myoc reveals the role of myocilin in zebrafish sex determination associated with Wnt signalling downregulation

    Article • November 2020, Cold Spring Harbor Laboratory Press

    Professor Julio Escribano

  8. Role of GUCA1C in Primary Congenital Glaucoma and in the Retina: Functional Evaluation in Zebrafish

    Article • Genes, May 2020, MDPI AG

    Professor Julio Escribano

  9. CPAMD8 loss-of-function underlies non-dominant congenital glaucoma with variable anterior segment dysgenesis and abnormal extracellular matrix

    Article • Human Genetics, April 2020, Springer Science + Business Media

    Professor Julio Escribano

  10. Role of GUCA1C in Primary Congenital Glaucoma and in the Retina: Functional Evaluation in Zebrafish

    Article • March 2020, MDPI AG

    Professor Julio Escribano

  11. Current perspectives in Bietti crystalline dystrophy

    Article • Clinical Ophthalmology, July 2019, Dove Medical Press

    Professor Julio Escribano

  12. Transforming growth factor beta‐induced p.(L558P) variant is associated with autosomal dominant lattice corneal dystrophy type IV in a large cohort of Spanish patients

    Article • Clinical and Experimental Ophthalmology, May 2019, Wiley

    Professor Julio Escribano

  13. Cataract extraction in patients with primary congenital glaucoma

    Article • European Journal of Ophthalmology, April 2019, SAGE Publications

    Professor Julio Escribano

  14. Role of FOXC2 and PITX2 rare variants associated with mild functional alterations as modifier factors in congenital glaucoma

    Article • PLoS ONE, January 2019, PLOS

    Professor Julio Escribano

  15. Identification of myocilin as a blood plasma protein and analysis of its role in leukocyte adhesion to endothelial cell monolayers

    Article • PLoS ONE, December 2018, PLOS

    Professor Julio Escribano

  16. Identification of novel CYP4V2 genotypes associated with Bietti crystalline dystrophy and atypical anterior segment phenotypes in Spanish patients

    Article • Acta Ophthalmologica, April 2018, Wiley

    Professor Julio Escribano

  17. Informing the Transitions towards Low-carbon Societies

    Article • Energy Economics, October 2017, Elsevier

    Professor Julio Escribano

  18. Goniodysgenesis variability and activity of CYP1B1 genotypes in primary congenital glaucoma

    Article • PLoS ONE, April 2017, PLOS

    Professor Julio Escribano

  19. Whole-Exome Sequencing of Congenital Glaucoma Patients Reveals Hypermorphic Variants in GPATCH3, a New Gene Involved in Ocular and Craniofacial Development

    Article • Scientific Reports, April 2017, Nature

    Professor Julio Escribano

  20. Metallothionein polymorphisms in a Northern Spanish population with neovascular and dry forms of age-related macular degeneration

    Article • Ophthalmic Genetics, March 2017, Taylor & Francis

    Professor Julio Escribano

  21. A novel transient phase kinetic analysis of the fractional modification of monocyclic enzyme cascades

    Article • Journal of Mathematical Chemistry, July 2016, Springer Science + Business Media

    Professor Julio Escribano

  22. Functional characterization of eight rare missenseCYP1B1variants involved in congenital glaucoma and their association with null genotypes

    Article • Acta Ophthalmologica, April 2016, Wiley

    Professor Julio Escribano

  23. The Role of hsa-miR-548l Dysregulation as a Putative Modifier Factor for Glaucoma-Associated FOXC1 Mutations

    Article • MicroRNA, September 2015, Bentham Science Publishers

    Professor Julio Escribano

  24. LOXL1 gene variants and their association with pseudoexfoliation glaucoma (XFG) in Spanish patients

    Article • BMC Medical Genetics, August 2015, Springer Science + Business Media

    Professor Julio Escribano

  25. Rare FOXC1 variants in congenital glaucoma: identification of translation regulatory sequences

    Article • European Journal of Human Genetics, July 2015, Nature

    Professor Julio Escribano

  26. CFHpolymorphisms in a Northern Spanish population with neovascular and dry forms of age-related macular degeneration

    Article • Acta Ophthalmologica, July 2015, Wiley

    Professor Julio Escribano

  27. Molecular and neurochemical substrates of the audiogenic seizure strains: The GASH:Sal model

    Article • Epilepsy & Behavior, June 2015, Elsevier

    Professor Julio Escribano

  28. Hypo- and Hypermorphic FOXC1 Mutations in Dominant Glaucoma: Transactivation and Phenotypic Variability

    Article • PLoS ONE, March 2015, PLOS

    Professor Julio Escribano

  29. Clinical Variability of Primary Congenital Glaucoma in a Spanish Family With Cyp1b1 Gene Mutations

    Article • Journal of Glaucoma, January 2015, Wolters Kluwer Health

    Professor Julio Escribano

  30. Analysis of the fractional modification of the monocyclic enzyme cascades, defined in an alternative way involving the two forms of the modified protein

    Article • Journal of Mathematical Chemistry, August 2014, Springer Science + Business Media

    Professor Julio Escribano

  31. Comparative proteomic study in serum of patients with primary open-angle glaucoma and pseudoexfoliation glaucoma

    Article • Journal of Proteomics, February 2014, Elsevier

    Professor Julio Escribano

  32. Genotype–Phenotype Analysis of Bietti Crystalline Dystrophy in a Family with the CYP4V2 Ile111Thr Mutation

    Article • Cornea, July 2013, Wolters Kluwer Health

    Professor Julio Escribano

  33. Co‐inheritance of HNF1a and GCK mutations in a family with maturity‐onset diabetes of the young (MODY): implications for genetic testing

    Article • Clinical Endocrinology, April 2013, Wiley

    Professor Julio Escribano

  34. Null CYP1B1 Genotypes in Primary Congenital and Nondominant Juvenile Glaucoma

    Article • Ophthalmology, April 2013, Elsevier

    Professor Julio Escribano

  35. Bicarbonate-Dependent Secretion and Proteolytic Processing of Recombinant Myocilin

    Article • PLoS ONE, January 2013, PLOS

    Professor Julio Escribano

  36. GSTT1, GSTM1, and CYP1B1 gene polymorphisms and susceptibility to sporadic renal cell cancer

    Article • Urologic Oncology Seminars and Original Investigations, November 2012, Elsevier

    Professor Julio Escribano

  37. Recent Patents and Developments in Glaucoma Biomarkers

    Article • Recent Patents on Endocrine Metabolic & Immune Drug Discovery, August 2012, Bentham Science Publishers

    Professor Julio Escribano

  38. Opposite caudal versus rostral brain nitric oxide synthase response to generalized seizures in a novel rodent model of reflex epilepsy

    Article • Life Sciences, April 2012, Elsevier

    Professor Julio Escribano

  39. Role of CYP1B1 Gene Polymorphisms in Bladder Cancer Susceptibility

    Article • The Journal of Urology, February 2012, Elsevier

    Professor Julio Escribano

  40. Triterpenoid saponins from corms of Crocus sativus: Localization, extraction and characterization

    Article • Industrial Crops and Products, November 2011, Elsevier

    Professor Julio Escribano

  41. WDR36andP53Gene Variants and Susceptibility to Primary Open-Angle Glaucoma: Analysis of Gene-Gene Interactions

    Article • Investigative Ophthalmology & Visual Science, October 2011, Association for Research in Vision and Ophthalmology (ARVO)

    Professor Julio Escribano

  42. Importance of clinical variables in the diagnosis of MODY2 and MODY3

    Article • Endocrinología y Nutrición, August 2011, Elsevier

    Professor Julio Escribano

  43. Importance of clinical variables in the diagnosis of MODY2 and MODY3

    Article • Endocrinología y Nutrición (English Edition), August 2011, Elsevier

    Professor Julio Escribano

  44. Interaction of Recombinant Myocilin with the Matricellular Protein SPARC: Functional Implications

    Article • Investigative Ophthalmology & Visual Science, January 2011, Association for Research in Vision and Ophthalmology (ARVO)

    Professor Julio Escribano

  45. Genética del glaucoma: la luz al final del túnel catorce años después

    Article • Archivos de la Sociedad Española de Oftalmología, November 2010, Elsevier

    Professor Julio Escribano

  46. Polymorphic deletions of the GSTT1 and GSTM1 genes and susceptibility to bladder cancer

    Article • BJU International, October 2010, Wiley

    Professor Julio Escribano

  47. A general model for non-autocatalytic zymogen activation in the presence of two different and mutually exclusive inhibitors. I. Kinetic analysis

    Article • Journal of Mathematical Chemistry, May 2010, Springer Science + Business Media

    Professor Julio Escribano

  48. A general model for non-autocatalytic zymogen activation in the presence of two different and mutually exclusive inhibitors. II. Relative weight of activation and inhibition processes

    Article • Journal of Mathematical Chemistry, May 2010, Springer Science + Business Media

    Professor Julio Escribano

  49. Functional Role of Proteolytic Processing of Recombinant Myocilin in Self-Aggregation

    Article • Investigative Ophthalmology & Visual Science, January 2010, Association for Research in Vision and Ophthalmology (ARVO)

    Professor Julio Escribano

  50. Clinical differences between patients with MODY-3, MODY-2 and type 2 diabetes mellitus with I27L polymorphism in the HNF1α gene

    Article • Endocrinología y Nutrición, January 2010, Elsevier

    Professor Julio Escribano

  51. Functional analysis ofCYP1B1mutations and association of heterozygous hypomorphic alleles with primary open-angle glaucoma

    Article • Clinical Genetics, January 2010, Wiley

    Professor Julio Escribano

  52. Primary congenital glaucoma caused by the homozygous F261LCYP1B1mutation and paternal isodisomy of chromosome 2

    Article • Clinical Genetics, December 2009, Wiley

    Professor Julio Escribano

  53. Implications of p53 gene mutations on patient survival in transitional cell carcinoma of the bladder: A long-term study

    Article • Urologic Oncology Seminars and Original Investigations, November 2008, Elsevier

    Professor Julio Escribano

  54. Implications of mismatch repair genes hMLH1and hMSH2in patients with sporadic renal cell carcinoma

    Article • BJU International, August 2008, Wiley

    Professor Julio Escribano

  55. Expression and purification of functional recombinant human pigment epithelium-derived factor (PEDF) secreted by the yeast Pichia pastoris

    Article • Journal of Biotechnology, March 2008, Elsevier

    Professor Julio Escribano

  56. VHL Protein Alterations in Sporadic Renal Cell Carcinoma

    Article • Clinical Oncology, December 2007, Elsevier

    Professor Julio Escribano

  57. Mental Health and Functional Outcomes of Maternal and Adolescent Reports of Adolescent Depressive Symptoms

    Article • Journal of the American Academy of Child & Adolescent Psychiatry, September 2007, Elsevier

    Anita Thapar, Professor Julio Escribano

  58. Characterization of the Intracellular Proteolytic Cleavage of Myocilin and Identification of Calpain II as a Myocilin-processing Protease

    Article • Journal of Biological Chemistry, July 2007, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Julio Escribano

  59. New perspectives in aqueous humor secretion and in glaucoma: The ciliary body as a multifunctional neuroendocrine gland

    Article • Progress in Retinal and Eye Research, May 2007, Elsevier

    Professor Julio Escribano

  60. Sensitivity and Specificity of P53 Protein Detection by Immunohistochemistry in Patients with Urothelial Bladder Carcinoma

    Article • Urologia Internationalis, January 2007, Karger Publishers

    Professor Julio Escribano

  61. Using ankle-brachial index to detect peripheral arterial disease: Prevalence and associated risk factors in a random population sample

    Article • Nutrition Metabolism and Cardiovascular Diseases, January 2007, Elsevier

    Professor Julio Escribano

  62. Kinetic analysis of a general model of activation of aspartic proteinase zymogens involving a reversible inhibitor. II. Contribution of the uni- and bimolecular activation routes

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, January 2007, Taylor & Francis

    Professor Julio Escribano

  63. Identification of a Lipase-linked Cell Membrane Receptor for Pigment Epithelium-derived Factor

    Article • Journal of Biological Chemistry, October 2006, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Christina Meyer, Professor Julio Escribano

  64. Determination of vhl Gene Mutations in Sporadic Renal Cell Carcinoma

    Article • European Urology, June 2006, Elsevier

    Professor Julio Escribano

  65. Hipermetilación del promotor del gen reparador hMLH1 en la patogenia del carcinoma de células renales esporádico

    Article • Medicina Clínica, April 2006, Elsevier

    Professor Julio Escribano

  66. Pigment epithelium–derived factor is a niche signal for neural stem cell renewal

    Article • Nature Neuroscience, February 2006, Nature

    Professor Julio Escribano

  67. Interaction of myocilin with the C-terminal region of hevin

    Article • Biochemical and Biophysical Research Communications, January 2006, Elsevier

    Professor Julio Escribano

  68. Relationship between the Arg72Pro Polymorphism of p53 and outcome for patients with traumatic brain injury

    Article • Intensive Care Medicine, July 2005, Springer Science + Business Media

    Professor Julio Escribano

  69. Myocilin Mutations Causing Glaucoma Inhibit the Intracellular Endoproteolytic Cleavage of Myocilin between Amino Acids Arg226 and Ile227

    Article • Journal of Biological Chemistry, March 2005, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Julio Escribano

  70. DEVELOPMENT AND GENE EXPRESSION IN SAFFRON CORMS

    Article • Acta Horticulturae, May 2004, International Society for Horticultural Science (ISHS)

    Professor Julio Escribano

  71. PRESENCE OF BIOACTIVE GLYCOCONJUGATES ON DIFFERENT STAGES OF SAFFRON CORM

    Article • Acta Horticulturae, May 2004, International Society for Horticultural Science (ISHS)

    Professor Julio Escribano

  72. p53 Gene Mutations in Superficial Bladder Cancer

    Article • Urologia Internationalis, January 2004, Karger Publishers

    Professor Julio Escribano

  73. Sex steroid hormone metabolism takes place in human ocular cells

    Article • The Journal of Steroid Biochemistry and Molecular Biology, August 2003, Elsevier

    Professor Julio Escribano

  74. Prognostic Implications of p53 Gene Mutations in Bladder Tumors

    Article • The Journal of Urology, February 2003, Elsevier

    Professor Julio Escribano

  75. Identification of a Neuropeptide and Neuropeptide-Processing Enzymes in Aqueous Humor Confers Neuroendocrine Features to the Human Ocular Ciliary Epithelium

    Article • Journal of Neurochemistry, November 2002, Wiley

    Professor Julio Escribano

  76. Comparison of three different PCR methods for detection of Brucella spp. in human blood samples

    Article • FEMS Immunology & Medical Microbiology, October 2002, Wiley

    Professor Julio Escribano

  77. Threonines at position 174 and 235 of the angiotensinogen polypeptide chain are related to familial history of hypertension in a Spanish-Mediterranean population

    Article • British Journal of Biomedical Science, January 2002, Taylor & Francis

    Professor Julio Escribano

  78. Expression of the TIGR gene in the iris, ciliary body, and trabecular meshwork of the human eye

    Article • Ophthalmic Genetics, September 2000, Swets & Zeitlinger Publishers

    Professor Julio Escribano

  79. A glycoconjugate from corms of saffron plant (Crocus sativus L.) inhibits root growth and affects in vitro cell viability

    Article • Journal of Experimental Botany, April 2000, Oxford University Press (OUP)

    Professor Julio Escribano

  80. A glycoconjugate from corms of saffron plant ( Crocus sativus L.) inhibits root growth and affects in vitro cell viability

    Article • Journal of Experimental Botany, April 2000, Oxford University Press (OUP)

    Professor Julio Escribano

  81. The Cytolytic Effect of a Glycoconjugate Extracted from Corms of Saffron Plant (Crocus sativus) on Human Cell Lines in Culture

    Article • Planta Medica, March 2000, Thieme Publishing Group

    Professor Julio Escribano

  82. Purification and Characterization of a Mannan-Binding Lectin Specifically Expressed in Corms of Saffron Plant ( Crocus s ativus L.)

    Article • Journal of Agricultural and Food Chemistry, February 2000, American Chemical Society (ACS)

    Professor Julio Escribano

  83. Angiotensin-converting enzyme (ACE) gene polymorphisms, serum ACE activity and blood pressure in a Spanish-Mediterranean population

    Article • Journal of Human Hypertension, February 2000, Nature

    Professor Julio Escribano

  84. A Glycoconjugate Isolated from the Saffron Plant (Crocus sativus L.) is Cytolytic Against Tumoral Cells and Activates Macrophages In Vitro

    Article • January 2000, Springer Science + Business Media

    Professor Julio Escribano

  85. A Proteoglycan from Saffron Corm (Crocus sativus L.) Inhibits Root Elongation of Nicotiana tabacum Seedlings and is Highly Cytotoxic on Tobacco Cells and Protoplasts

    Article • January 2000, Springer Science + Business Media

    Professor Julio Escribano

  86. Expression of the TIGR gene in the iris, ciliary body, and trabecular meshwork of the human eye

    Article • Ophthalmic Genetics, January 2000, Swets & Zeitlinger Publishers

    Professor Julio Escribano

  87. Effects of Long-Term Treatment of Colon Adenocarcinoma With Crocin, a Carotenoid From Saffron (Crocus sativus L.): An Experimental Study in the Rat

    Article • Nutrition and Cancer, November 1999, Taylor & Francis

    Professor Julio Escribano

  88. In vitro activation of macrophages by a novel proteoglycan isolated from corms of Crocus sativus L

    Article • Cancer Letters, September 1999, Elsevier

    Professor Julio Escribano

  89. Differential gene expression in the human ciliary epithelium

    Article • Progress in Retinal and Eye Research, July 1999, Elsevier

    Professor Julio Escribano

  90. Production of a cytotoxic proteoglycan using callus culture of saffron corms (Crocus sativus L.)

    Article • Journal of Biotechnology, July 1999, Elsevier

    Professor Julio Escribano

  91. Identification, expression and chromosome localization of a human gene encoding a novel protein with similarity to the pilB family of transcriptional factors (pilin) and to bacterial peptide methionine sulfoxide reductases

    Article • Gene, June 1999, Elsevier

    Professor Julio Escribano

  92. Associated evaluation of differents variants of Angiotensinogen gen and the relation with blood pressure levels. Results of an epidemiologic study

    Article • American Journal of Hypertension, April 1999, Oxford University Press (OUP)

    Professor Julio Escribano

  93. Relationship between variants of AT1R gene with blood pressure levels in a spanish population. Results of an epidemiologic study

    Article • American Journal of Hypertension, April 1999, Oxford University Press (OUP)

    Professor Julio Escribano

  94. Isolation and cytotoxic properties of a novel glycoconjugate from corms of saffron plant (Crocus sativus L.)

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, January 1999, Elsevier

    Professor Julio Escribano

  95. Development of cormogenic nodules and microcorms by tissue culture, a new tool for the multiplication and genetic improvement of saffron

    Article • Agronomie, January 1999, EDP Sciences

    Professor Julio Escribano

  96. Genetics of hypertension in a Spanish population. Results from epidemiologic study, with a case-control population-based design

    Article • American Journal of Hypertension, April 1998, Oxford University Press (OUP)

    Professor Julio Escribano

  97. Cloning and characterization of subtracted cDNAs from a human ciliary body library encoding TIGR , a protein involved in juvenile open angle glaucoma with homology to myosin and olfactomedin

    Article • FEBS Letters, August 1997, Wiley

    Professor Julio Escribano

  98. Gene Expression of Proteases and Protease Inhibitors in the Human Ciliary Epithelium and ODM-2 Cells

    Article • Experimental Eye Research, August 1997, Elsevier

    Professor Julio Escribano

  99. Treatment of human brucellosis with doxycycline and gentamicin.

    Article • Antimicrobial Agents and Chemotherapy, January 1997, ASM Journals

    Professor Julio Escribano

  100. Crocin, safranal and picrocrocin from saffron (Crocus sativus L.) inhibit the growth of human cancer cells in vitro

    Article • Cancer Letters, February 1996, Elsevier

    Professor Julio Escribano

  101. Spectroscopic characterization by photodiode array detection of human urinary and amniotic protein HC subpopulations fractionated by anion-exchange and size-exclusion high-performance liquid chromatography

    Article • Journal of Chromatography A, January 1996, Elsevier

    Professor Julio Escribano

  102. Isolation and Characterization of Cell-Specific cDNA Clones from a Subtractive Library of the Ocular Ciliary Body of a Single Normal Human Donor: Transcription and Synthesis of Plasma Proteins

    Article • The Journal of Biochemistry, October 1995, Oxford University Press (OUP)

    Professor Julio Escribano

  103. cDNA from human ocular ciliary epithelium homologous to ?ig-h3 is preferentially expressed as an extracellular protein in the corneal epithelium

    Article • Journal of Cellular Physiology, September 1994, Wiley

    Professor Julio Escribano

  104. Efficient thyroid hormone formation by in vitro iodination of a segment of rat thyroglobulin fused to Staphylococcal protein A

    Article • FEBS Letters, February 1992, Wiley

    Professor Julio Escribano

  105. Identification of peptides containing aromatic amino acids, cysteine, iodotyrosine and iodothyronine by high-performance liquid chromatography with photodiode-array detection

    Article • Journal of Chromatography A, July 1990, Elsevier

    Professor Julio Escribano

  106. Location and characterization of the three carbohydrate prosthetic groups of human protein HC

    Article • FEBS Letters, June 1990, Wiley

    Professor Julio Escribano

  107. Direct Characterization of Proteins and Peptides in HPLC by Photodiode Array UV-VIS Detection: A New Approach in the Detection and Characterization of Polypeptides

    Article • January 1989, Springer Science + Business Media

    Professor Julio Escribano

  108. Identification of retinol as one of the protein HC chromophores

    Article • Biochemical and Biophysical Research Communications, September 1988, Elsevier

    Professor Julio Escribano

  109. High-performance liquid chromatography and photodiode-array detection of the human protein HC (human complex-forming glycoprotein heterogeneous in charge), a chromophore-associated protein

    Article • Journal of Chromatography A, July 1988, Elsevier

    Professor Julio Escribano