All Stories

  1. Transforming growth f actor‐beta1 and m yeloid‐derived suppressor cells: A cancerous partnership

    Article • Developmental Dynamics, April 2021, Wiley

    Dr Juan F Santibanez

  2. Transforming Growth Factor-Beta and Urokinase Type Plasminogen Interplay in Cancer

    Article • Current Protein and Peptide Science, October 2018, Bentham Science Publishers

    Dr Juan F Santibanez

  3. Regulation of Mesenchymal Stem Cell Differentiation by Transforming Growth Factor Beta Superfamily

    Article • Current Protein and Peptide Science, October 2018, Bentham Science Publishers

    Dr Juan F Santibanez, Dr. Drenka Trivanovic, Diana Bugarski

  4. Estramustine Phosphate Inhibits TGF-β-Induced Mouse Macrophage Migration and Urokinase-Type Plasminogen Activator Production

    Article • Analytical Cellular Pathology, September 2018, Hindawi Publishing Corporation

    Dr Juan F Santibanez

  5. Novel Patents Targeting Interleukin-17A; Implications in Cancer and Inflammation

    Article • Recent Patents on Anti-Cancer Drug Discovery, May 2018, Bentham Science Publishers

    Dr Juan F Santibanez

  6. Urokinase Type Plasminogen Activator and the Molecular Mechanisms of its Regulation in Cancer

    Article • Protein and Peptide Letters, January 2018, Bentham Science Publishers

    Dr Juan F Santibanez

  7. Transforming Growth Factor-Beta and Myeloid-Derived Suppressor Cells Interplay in Cancer

    Article • The Open Cancer Immunology Journal, October 2017, Bentham Science Publishers

    Dr Juan F Santibanez

  8. Mesenchymal stromal cell engagement in cancer cell epithelial to mesenchymal transition

    Article • Developmental Dynamics, October 2017, Wiley

    Dr Juan F Santibanez, Dr. Drenka Trivanovic

  9. Transforming growth factor-β, matrix metalloproteinases, and urokinase-type plasminogen activator interaction in the cancer epithelial to mesenchymal transition

    Article • Developmental Dynamics, August 2017, Wiley

    Dr Juan F Santibanez

  10. Metabolic Plasticity of Stem Cells and Macrophages in Cancer

    Article • Frontiers in Immunology, August 2017, Frontiers

    Dr Juan F Santibanez

  11. Obesity: An Emerging Importance of Progenitors

    Article • Immunology Endocrine & Metabolic Agents - Medicinal Chemistry, July 2017, Bentham Science Publishers

    Dr Juan F Santibanez, Dr. Drenka Trivanovic

  12. Lipopolysaccharide can modify differentiation and immunomodulatory potential of periodontal ligament stem cells via ERK1,2 signaling

    Article • Journal of Cellular Physiology, May 2017, Wiley

    Dr Juan F Santibanez, Dr. Drenka Trivanovic, Diana Bugarski

  13. Oxidative Stress in Disease and Aging: Mechanisms and Therapies 2016

    Article • Oxidative Medicine and Cellular Longevity, January 2017, Hindawi Publishing Corporation

    Dr Juan F Santibanez

  14. TGF-β Signalling and Its Role in Cancer Progression and Metastasis

    Article • August 2016, Wiley

    Dr Juan F Santibanez

  15. Mesenchymal Stem Cells from Different Tissues: Immune Status and Activity

    Article • Journal of Immunology and Infectious Diseases, April 2016, Annex Publishers, LLC

    Dr Juan F Santibanez

  16. Interleukin-17 Receptor A

    Article • January 2016, Springer Science + Business Media

    Dr Juan F Santibanez

  17. Transforming Growth Factor-Beta and Matrix Metalloproteinases Functional Interplay in Cancer; Implications in Epithelial to Mesenchymal Transition

    Article • Cell Biology Research & Therapy, January 2016, OMICS Publishing Group

    Dr Juan F Santibanez

  18. Doxycycline Inhibits IL-17-Stimulated MMP-9 Expression by Downregulating ERK1/2 Activation: Implications in Myogenic Differentiation

    Article • Mediators of Inflammation, January 2016, Hindawi Publishing Corporation

    Dr Juan F Santibanez

  19. The Roles of Mesenchymal Stromal/Stem Cells in Tumor Microenvironment Associated with Inflammation

    Article • Mediators of Inflammation, January 2016, Hindawi Publishing Corporation

    Dr Juan F Santibanez

  20. Mesenchymal stem cells of different origin: Comparative evaluation of proliferative capacity, telomere length and pluripotency marker expression

    Article • Life Sciences, November 2015, Elsevier

    Dr Juan F Santibanez

  21. Novel Patents and Cancer Therapies for Transforming Growth Factor-β and Urokinase Type Plasminogen Activator: Potential Use of Their Interplay in Tumorigenesis

    Article • October 2015, Bentham Science Publishers

    Dr Juan F Santibanez

  22. An Overview of Interleukin-17A and Interleukin-17 Receptor A Structure, Interaction and Signaling

    Article • Protein and Peptide Letters, June 2015, Bentham Science Publishers

    Dr Juan F Santibanez

  23. Transforming growth factor-beta differently regulates urokinase type plasminogen activator and matrix metalloproteinase-9 expression in mouse macrophages; analysis of intracellular signal transduction

    Article • Cell Biology International, February 2015, Wiley

    Dr Juan F Santibanez

  24. Interleukin-17 and Its Implication in the Regulation of Differentiation and Function of Hematopoietic and Mesenchymal Stem Cells

    Article • Mediators of Inflammation, January 2015, Hindawi Publishing Corporation

    Dr Juan F Santibanez

  25. Transforming Growth Factor-Beta and Oxidative Stress Interplay: Implications in Tumorigenesis and Cancer Progression

    Article • Oxidative Medicine and Cellular Longevity, January 2015, Hindawi Publishing Corporation

    Dr Juan F Santibanez

  26. Novel Patents and Cancer Therapies for Transforming Growth Factor- Beta and Urokinase Type Plasminogen Activator: Potential Use of Their Interplay in Tumorigenesis

    Article • Recent Patents on Anti-Cancer Drug Discovery, July 2014, Bentham Science Publishers

    Dr Juan F Santibanez

  27. Janus Kinase 2 and Transforming Growth Factor Beta Signal Transduction Targeted Therapies in BCR/ABL-Negative Myeloproliferative Neoplasms

    Article • May 2014, Bentham Science Publishers

    Dr Juan F Santibanez

  28. Transforming Growth Factor-Beta and Matrix Metalloproteinases: Functional Interactions in Tumor Stroma-Infiltrating Myeloid Cells

    Article • The Scientific World JOURNAL, January 2014, Hindawi Publishing Corporation

    Dr Juan F Santibanez

  29. In vitro effects of IL-17 on angiogenic properties of endothelial cells in relation to oxygen levels

    Article • Cell Biology International, July 2013, Wiley

    Dr Juan F Santibanez

  30. Interleukin-17 modulates myoblast cell migration by inhibiting urokinase type plasminogen activator expression through p38 mitogen-activated protein kinase

    Article • The International Journal of Biochemistry & Cell Biology, February 2013, Elsevier

    Dr Juan F Santibanez

  31. The immunomodulatory activity of human mesenchymal stem cells is related to different tissue origin

    Article • Frontiers in Immunology, January 2013, Frontiers

    Dr Juan F Santibanez

  32. Skip Regulates TGF-β1-Induced Extracellular Matrix Degrading Proteases Expression in Human PC-3 Prostate Cancer Cells

    Article • Prostate Cancer, January 2013, Hindawi Publishing Corporation

    Dr Juan F Santibanez

  33. Mesenchymal stem cells isolated from peripheral blood and umbilical cord Wharton’s jelly

    Article • Srpski arhiv za celokupno lekarstvo, January 2013, National Library of Serbia

    Dr Juan F Santibanez

  34. Transforming Growth Factor-Beta and Urokinase-Type Plasminogen Activator: Dangerous Partners in Tumorigenesis—Implications in Skin Cancer

    Article • ISRN Dermatology, January 2013, Hindawi Publishing Corporation

    Dr Juan F Santibanez

  35. Immunomodulatory capacity of human mesenchymal stem cells isolated from adipose tissue, dental pulp, peripheral blood and umbilical cord Wharton’s jelly

    Article • Central European Journal of Immunology, January 2013, Termedia Sp. z.o.o.

    Dr Juan F Santibanez

  36. SMAD3 is essential for transforming growth factor-β1-induced urokinase type plasminogen activator expression and migration in transformed keratinocytes

    Article • European Journal of Cancer, July 2012, Elsevier

    Dr Juan F Santibanez

  37. Transforming growth factor-β superfamily, implications in development and differentiation of stem cells

    Article • BioMolecular Concepts, January 2012, De Gruyter

    Dr Juan F Santibanez

  38. SKIP Downregulation Increases TGF-β1-Induced Matrix Metalloproteinase-9 Production in Transformed Keratinocytes

    Article • Scientifica, January 2012, Hindawi Publishing Corporation

    Dr Juan F Santibanez

  39. IL-17 and FGF signaling involved in mouse mesenchymal stem cell proliferation

    Article • Cell and Tissue Research, December 2011, Springer Science + Business Media

    Dr Juan F Santibanez

  40. PS2-033. IL-17 stimulates expression of MMP-9 and uPAR in granulocytes

    Article • Cytokine, October 2011, Elsevier

    Dr Juan F Santibanez

  41. TGF-β/TGF-β receptor system and its role in physiological and pathological conditions

    Article • Clinical Science, September 2011, Portland Press Ltd.

    Dr Juan F Santibanez

  42. Synthesis, structural and spectroscopic characterization, in vitro cytotoxicity and in vivo activity as free radical scavengers of chlorido(p-cymene) complexes of ruthenium(II) containing N-alkylphenothiazines

    Article • European Journal of Medicinal Chemistry, September 2011, Elsevier

    Dr Juan F Santibanez

  43. SKIP is required for TGF-β1-induced epithelial mesenchymal transition and migration in transformed keratinocytes

    Article • FEBS Letters, October 2010, Wiley

    Dr Juan F Santibanez

  44. The TGF-β co-receptor endoglin modulates the expression and transforming potential of H-Ras

    Article • Carcinogenesis, September 2010, Oxford University Press (OUP)

    Dr Juan F Santibanez

  45. New ruthenium(II) complexes with N-alkylphenothiazines: Synthesis, structure, in vivo activity as free radical scavengers and in vitro cytotoxicity

    Article • European Journal of Medicinal Chemistry, September 2010, Elsevier

    Dr Juan F Santibanez

  46. ROS-NFκΒ mediates TGF-β1-induced expression of urokinase-type plasminogen activator, matrix metalloproteinase-9 and cell invasion

    Article • Molecular and Cellular Biochemistry, March 2010, Springer Science + Business Media

    Dr Juan F Santibanez

  47. The Role of the TGF-β Coreceptor Endoglin in Cancer

    Article • The Scientific World JOURNAL, January 2010, Hindawi Publishing Corporation

    Dr Juan F Santibanez

  48. Spred2 inhibits TGF-β1-induced urokinase type plasminogen activator expression, cell motility and epithelial mesenchymal transition

    Article • International Journal of Cancer, November 2009, Wiley

    Dr Juan F Santibanez, Victor Hugo Villar cortes

  49. Structural Antitumoral Activity Relationships of Synthetic Chalcones

    Article • International Journal of Molecular Sciences, January 2009, MDPI AG

    Dr Juan F Santibanez

  50. RAC1 activity and intracellular ROS modulate the migratory potential of MCF-7 cells through a NADPH oxidase and NFκB-dependent mechanism

    Article • Cancer Letters, August 2008, Elsevier

    Dr Juan F Santibanez

  51. Caveolin-1 interacts and cooperates with the transforming growth factor-β type I receptor ALK1 in endothelial caveolae

    Article • Cardiovascular Research, December 2007, European Society of Cardiology

    Dr Juan F Santibanez

  52. Endoglin increases eNOS expression by modulating Smad2 protein levels and Smad2-dependent TGF-β signaling

    Article • Journal of Cellular Physiology, February 2007, Wiley

    Professor Jose M Lopez-Novoa, Dr Juan F Santibanez

  53. JNK mediates TGF-β1-induced epithelial mesenchymal transdifferentiation of mouse transformed keratinocytes

    Article • FEBS Letters, September 2006, Wiley

    Dr Juan F Santibanez

  54. Hyperosmotic stress-dependent NFκB activation is regulated by reactive oxygen species and IGF-1 in cultured cardiomyocytes

    Article • FEBS Letters, July 2006, Wiley

    Dr Juan F Santibanez

  55. Ha-Ras sensitizes transformed mouse skin cells to Anisomycin-induced apoptosis

    Article • FEBS Letters, November 2005, Wiley

    Dr Juan F Santibanez

  56. Interaction and functional interplay between endoglin and ALK-1, two components of the endothelial transforming growth factor-β receptor complex

    Article • Journal of Cellular Physiology, January 2005, Wiley

    Dr Juan F Santibanez

  57. Epidermal growth factor stimulates urokinase-type plasminogen activator expression in human gingival fibroblasts. Possible modulation by genistein and curcumin

    Article • Journal of Periodontal Research, December 2004, Wiley

    Dr Juan F Santibanez

  58. EGF receptor transactivation by urokinase receptor stimulus through a mechanism involving Src and matrix metalloproteinases

    Article • Experimental Cell Research, January 2004, Elsevier

    Dr Juan F Santibanez

  59. Cyclic AMP inhibits TGFβ1-induced cell-scattering and invasiveness in murine-transformed keratinocytes

    Article • International Journal of Cancer, August 2003, Wiley

    Dr Juan F Santibanez

  60. Transforming growth factor-β1 modulates matrix metalloproteinase-9 production through the Ras/MAPK signaling pathway in transformed keratinocytes

    Article • Biochemical and Biophysical Research Communications, August 2002, Elsevier

    Dr Juan F Santibanez

  61. TGF-β1and Smad4 overexpression induce a less invasive phenotype in highly invasive spindle carcinoma cells

    Article • FEBS Letters, May 2002, Wiley

    Dr Juan F Santibanez

  62. Involvement of the Ras/MAPK Signaling Pathway in the Modulation of Urokinase Production and Cellular Invasiveness by Transforming Growth Factor-β1 in Transformed Keratinocytes

    Article • Biochemical and Biophysical Research Communications, July 2000, Elsevier

    Dr Juan F Santibanez

  63. Genistein and Curcumin Block TGF-β1-Induced u-PA Expression and Migratory and Invasive Phenotype in Mouse Epidermal Keratinocytes

    Article • Nutrition and Cancer, May 2000, Taylor & Francis

    Dr Juan F Santibanez

  64. Bone extracellular matrix stimulates invasiveness of estrogen‐responsive human mammary MCF‐7 cells

    Article • International Journal of Cancer, October 1999, Wiley

    Dr Juan F Santibanez

  65. Urokinase expression and binding activity associated with the transforming growth factor β1‐induced migratory and invasive phenotype of mouse epidermal keratinocytes

    Article • Journal of Cellular Biochemistry, July 1999, Wiley

    Dr Juan F Santibanez

  66. Effect of desialylated human chorionic gonadotropin (hCG) on the bioactivity of rat Leydig cells

    Article • Cell Biochemistry and Function, March 1998, Wiley

    Dr Juan F Santibanez

  67. Soluble factors produced by PC-3 prostate cells decrease collagen content and mineralisation rate in fetal rat osteoblasts in culture

    Article • British Journal of Cancer, August 1996, Nature

    Dr Juan F Santibanez

  68. Prostate-derived soluble factors block osteoblast differentiation in culture

    Article • Journal of Cellular Biochemistry, April 1996, Wiley

    Dr Juan F Santibanez

  69. The secretion of urokinase-like plasminogen activator is inhibited by microtubule-interacting drugs

    Article • Cell Biochemistry and Function, September 1995, Wiley

    Dr Juan F Santibanez

  70. Membrane-associated procollagenase of leukemic cells is activated by urokinase-type plasminogen activator

    Article • Leukemia Research, December 1993, Elsevier

    Dr Juan F Santibanez

  71. Extracellular calcium modulates proliferation of factor dependent hemopoietic cells

    Article • Cell Biochemistry and Function, June 1993, Wiley

    Dr Juan F Santibanez

  72. Binding and production of insulin-like growth factor-I in rat mammary gland

    Article • Comparative Biochemistry and Physiology Part A Physiology, January 1991, Elsevier

    Dr Juan F Santibanez