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  1. Extraction of Cannabinoids and Terpenes from Hemp Flowers and Leaves (Cannabis sativa L., Futura 75): Chemical Profiling and Evaluation of Anticancer Properties

    Article • Molecules, March 2025, MDPI AG

    Prof. Joanna Wietrzyk

  2. New Difunctional Derivatives of Betulin: Preparation, Characterization and Antiproliferative Potential

    Article • Molecules, January 2025, MDPI AG

    Prof. Joanna Wietrzyk

  3. 4-Pyridone-3-carboxamide-1-β-D-ribonucleoside Reduces Cyclophosphamide Effects and Induces Endothelial Inflammation in Murine Breast Cancer Model

    Article • International Journal of Molecular Sciences, December 2024, MDPI AG

    Prof. Joanna Wietrzyk

  4. Vibrational and DFT Studies and Anticancer Activity of Novel Pd(II) and Pt(II) Complexes with Chloro Derivatives of 7-Azaindole-3-Carbaldehyde

    Article • Molecules, December 2024, MDPI AG

    Prof. Joanna Wietrzyk

  5. Synthesis, Structure, and In Vitro Biological Evaluation of Semi-Synthetic Derivatives of Betulin

    Article • Applied Sciences, October 2024, MDPI AG

    Prof. Joanna Wietrzyk

  6. Synergistic Proliferation Effects of Xanthohumol and Niflumic Acid on Merkel and Glioblastoma Cancer Cells: Role of Cell Membrane Interactions

    Article • International Journal of Molecular Sciences, October 2024, MDPI AG

    Prof. Joanna Wietrzyk

  7. 4-Hydroxybenzoic Acid-Based Hydrazide–Hydrazones as Potent Growth Inhibition Agents of Laccase-Producing Phytopathogenic Fungi That Are Useful in the Protection of Oilseed Crops

    Article • Molecules, May 2024, MDPI AG

    Prof. Joanna Wietrzyk

  8. Age-Dependent Effect of Calcitriol on Mouse Regulatory T and B Lymphocytes

    Article • Nutrients, December 2023, MDPI AG

    Prof. Joanna Wietrzyk

  9. An Organofluorine Isoselenocyanate Analogue of Sulforaphane Affects Antimetabolite 5-Fluorouracil’s Anticancer Activity: A Perspective for New Combinatory Therapy in Triple-Negative Breast Cancer

    Article • Molecules, August 2023, MDPI AG

    Prof. Joanna Wietrzyk

  10. Prenylated Flavonoids with Selective Toxicity against Human Cancers

    Article • International Journal of Molecular Sciences, April 2023, MDPI AG

    Prof. Joanna Wietrzyk

  11. Studies on the Complexation of Platinum(II) by Some 4-Nitroisoxazoles and Testing the Cytotoxic Activity of the Resulting Complexes

    Article • Molecules, January 2023, MDPI AG

    Prof. Joanna Wietrzyk

  12. Diclofenac Loaded Biodegradable Nanoparticles as Antitumoral and Antiangiogenic Therapy

    Article • Pharmaceutics, December 2022, MDPI AG

    Prof. Joanna Wietrzyk

  13. Cholinesterases Inhibition, Anticancer and Antioxidant Activity of Novel Benzoxazole and Naphthoxazole Analogs

    Article • Molecules, December 2022, MDPI AG

    Prof. Joanna Wietrzyk

  14. Novel Strategies against Cancer: Dexibuprofen-Loaded Nanostructured Lipid Carriers

    Article • International Journal of Molecular Sciences, September 2022, MDPI AG

    Prof. Joanna Wietrzyk

  15. Microfluidic-Assisted Human Cancer Cells Culturing Platform for Space Biology Applications

    Article • Sensors, August 2022, MDPI AG

    Prof. Joanna Wietrzyk

  16. Vitamin D, Th17 Lymphocytes, and Breast Cancer

    Article • Cancers, July 2022, MDPI AG

    Prof. Joanna Wietrzyk

  17. Discovery of New 3,3-Diethylazetidine-2,4-dione Based Thiazoles as Nanomolar Human Neutrophil Elastase Inhibitors with Broad-Spectrum Antiproliferative Activity

    Article • International Journal of Molecular Sciences, July 2022, MDPI AG

    Prof. Joanna Wietrzyk

  18. Synthesis, crystal structure and spectroscopic characterization of new anionic iridium(III) complexes and their interaction with biological targets

    Article • Polyhedron, July 2022, Elsevier

    Prof. Joanna Wietrzyk

  19. 4-Pyridone-3-carboxamide-1-β-D-ribonucleoside (4PYR)—A Novel Oncometabolite Modulating Cancer-Endothelial Interactions in Breast Cancer Metastasis

    Article • International Journal of Molecular Sciences, May 2022, MDPI AG

    Prof. Joanna Wietrzyk

  20. Relationship between Telomere Length, TERT Genetic Variability and TERT, TP53, SP1, MYC Gene Co-Expression in the Clinicopathological Profile of Breast Cancer

    Article • International Journal of Molecular Sciences, May 2022, MDPI AG

    Prof. Joanna Wietrzyk

  21. Micro-RNAs in Response to Active Forms of Vitamin D3 in Human Leukemia and Lymphoma Cells

    Article • International Journal of Molecular Sciences, April 2022, MDPI AG

    Prof. Joanna Wietrzyk

  22. The Impact of Exosomes/Microvesicles Derived from Myeloid Dendritic Cells Cultured in the Presence of Calcitriol and Tacalcitol on Acute B-Cell Precursor Cell Lines with MLL Fusion Gene

    Article • Journal of Clinical Medicine, April 2022, MDPI AG

    Prof. Joanna Wietrzyk

  23. Polymorphism of VDR Gene and the Sensitivity of Human Leukemia and Lymphoma Cells to Active Forms of Vitamin D

    Article • Cancers, January 2022, MDPI AG

    Prof. Joanna Wietrzyk

  24. BSG (CD147) Serum Level and Genetic Variants Are Associated with Overall Survival in Acute Myeloid Leukaemia

    Article • Journal of Clinical Medicine, January 2022, MDPI AG

    Prof. Joanna Wietrzyk

  25. Aromatic Bis[aminomethylidenebis(phosphonic)] Acids Prevent Ovariectomy-Induced Bone Loss and Suppress Osteoclastogenesis in Mice

    Article • International Journal of Molecular Sciences, September 2021, MDPI AG

    Prof. Joanna Wietrzyk

  26. Synthesis and antiproliferative screening of novel doubly modified colchicines containing urea, thiourea and guanidine moieties

    Article • Bioorganic & Medicinal Chemistry Letters, September 2021, Elsevier

    Prof. Joanna Wietrzyk

  27. Improved HDAC Inhibition, Stronger Cytotoxic Effect and Higher Selectivity against Leukemias and Lymphomas of Novel, Tricyclic Vorinostat Analogues

    Article • Pharmaceuticals, August 2021, MDPI AG

    Prof. Joanna Wietrzyk

  28. Synthesis and Structure of Novel Copper(II) Complexes with N,O- or N,N-Donors as Radical Scavengers and a Functional Model of the Active Sites in Metalloenzymes

    Article • International Journal of Molecular Sciences, July 2021, MDPI AG

    Prof. Joanna Wietrzyk

  29. Novel Vorinostat Analogues with Improved HDAC Inhibition, Stronger Cytotoxic Effect and Higher Selectivity Against Leukemias and Lymphomas

    Article • May 2021, MDPI AG

    Prof. Joanna Wietrzyk

  30. Effect of the dichloro-substitution on antiproliferative activity of phthalimide-thiazole derivatives. Rational design, synthesis, elastase, caspase 3/7, and EGFR tyrosine kinase activity and molecular modeling study

    Article • Bioorganic Chemistry, May 2021, Elsevier

    Prof. Joanna Wietrzyk

  31. Synthesis and Antiproliferative Activity of Triazoles Based on 2-Azabicycloalkanes

    Article • Materials, April 2021, MDPI AG

    Prof. Joanna Wietrzyk

  32. An insight into the anticancer potential of carbamates and thiocarbamates of 10-demethoxy-10-methylaminocolchicine

    Article • European Journal of Medicinal Chemistry, April 2021, Elsevier

    Prof. Joanna Wietrzyk

  33. Vitamin D Compounds PRI-2191 and PRI-2205 Enhance Anastrozole Activity in Human Breast Cancer Models

    Article • International Journal of Molecular Sciences, March 2021, MDPI AG

    Prof. Joanna Wietrzyk

  34. Differential Response of Lung Cancer Cells, with Various Driver Mutations, to Plant Polyphenol Resveratrol and Vitamin D Active Metabolite PRI-2191

    Article • International Journal of Molecular Sciences, February 2021, MDPI AG

    Prof. Joanna Wietrzyk

  35. Synthesis of novel phytol-derived γ-butyrolactones and evaluation of their biological activity

    Article • Scientific Reports, February 2021, Springer Science + Business Media

    Prof. Joanna Wietrzyk

  36. Synthesis, anticancer activity and molecular docking studies of N-deacetylthiocolchicine and 4-iodo-N-deacetylthiocolchicine derivatives

    Article • Bioorganic & Medicinal Chemistry, February 2021, Elsevier

    Prof. Joanna Wietrzyk

  37. Synthesis and Anticancer Evaluation of Novel Derivatives of Isoxazolo[4,5-e][1,2,4]triazepine Derivatives and Potential Inhibitors of Protein Kinase C

    Article • ACS Omega, December 2020, American Chemical Society (ACS)

    Prof. Joanna Wietrzyk

  38. Photoinduced Skeletal Rearrangement of N-Substituted Colchicine Derivatives

    Article • The Journal of Organic Chemistry, December 2020, American Chemical Society (ACS)

    Prof. Joanna Wietrzyk

  39. N‐Methylated Analogs of hIAPP Fragments 18–22, 23–27, 33–37 Inhibit Aggregation of the Amyloidogenic Core of the Hormone

    Article • Chemistry & Biodiversity, December 2020, Wiley

    Prof. Joanna Wietrzyk

  40. Synthesis of Platinum(II) Complexes with Some 1-Methylnitropyrazoles and In Vitro Research on Their Cytotoxic Activity

    Article • Pharmaceuticals, November 2020, MDPI AG

    Prof. Joanna Wietrzyk

  41. Calcitriol in the Presence of Conditioned Media from Metastatic Breast Cancer Cells Enhances Ex Vivo Polarization of M2 Alternative Murine Bone Marrow-Derived Macrophages

    Article • Cancers, November 2020, MDPI AG

    Prof. Joanna Wietrzyk

  42. Biaryl Sulfonamides Based on the 2-Azabicycloalkane Skeleton—Synthesis and Antiproliferative Activity

    Article • Materials, November 2020, MDPI AG

    Prof. Joanna Wietrzyk

  43. Vitamin D Metabolite Profile in Cholecalciferol- or Calcitriol-Supplemented Healthy and Mammary Gland Tumor-Bearing Mice

    Article • Nutrients, November 2020, MDPI AG

    Prof. Joanna Wietrzyk

  44. Heterogeneity of telomerase reverse transcriptase mutation and expression, telomerase activity and telomere length across human cancer cell lines cultured in vitro

    Article • Experimental Cell Research, November 2020, Elsevier

    Prof. Joanna Wietrzyk

  45. Protein Disulphide Isomerase A1 Is Involved in the Regulation of Breast Cancer Cell Adhesion and Transmigration via Lung Microvascular Endothelial Cells

    Article • Cancers, October 2020, MDPI AG

    Prof. Joanna Wietrzyk

  46. Differential Impact of Calcitriol and Its Analogs on Tumor Stroma in Young and Aged Ovariectomized Mice Bearing 4T1 Mammary Gland Cancer

    Article • International Journal of Molecular Sciences, September 2020, MDPI AG

    Prof. Joanna Wietrzyk

  47. New Human Islet Amyloid Polypeptide Fragments Susceptible to Aggregation

    Article • Chemistry & Biodiversity, September 2020, Wiley

    Prof. Joanna Wietrzyk

  48. Ruthenium(II) and Iridium(III) Complexes as Tested Materials for New Anticancer Agents

    Article • Materials, August 2020, MDPI AG

    Prof. Joanna Wietrzyk

  49. New Series of Double-Modified Colchicine Derivatives: Synthesis, Cytotoxic Effect and Molecular Docking

    Article • Molecules, August 2020, MDPI AG

    Prof. Joanna Wietrzyk

  50. Synthesis and Anticancer Activity of Dimeric Polyether Ionophores

    Article • Biomolecules, July 2020, MDPI AG

    Prof. Joanna Wietrzyk

  51. Octahydroquinoxalin-2(1H)-One-Based Aminophosphonic Acids and Their Derivatives—Biological Activity towards Cancer Cells

    Article • Materials, May 2020, MDPI AG

    Prof. Joanna Wietrzyk

  52. The halogenation of natural flavonoids, baicalein and chrysin, enhances their affinity to human protein kinase CK2

    Article • IUBMB Life, May 2020, Wiley

    Prof. Joanna Wietrzyk

  53. Synthesis, Antiproliferative Activity and Molecular Docking Studies of Novel Doubly Modified Colchicine Amides and Sulfonamides as Anticancer Agents

    Article • Molecules, April 2020, MDPI AG

    Prof. Joanna Wietrzyk

  54. Synthesis, biological evaluation and molecular docking studies of new amides of 4-chlorothiocolchicine as anticancer agents

    Article • Bioorganic Chemistry, April 2020, Elsevier

    Prof. Joanna Wietrzyk

  55. Three-Component Reaction of Diamines with Triethyl Orthoformate and Diethyl Phosphite and Anti-Proliferative and Antiosteoporotic Activities of the Products

    Article • Molecules, March 2020, MDPI AG

    Prof. Joanna Wietrzyk

  56. Retinol-Binding Protein 4 Accelerates Metastatic Spread and Increases Impairment of Blood Flow in Mouse Mammary Gland Tumors

    Article • Cancers, March 2020, MDPI AG

    Prof. Joanna Wietrzyk

  57. Synthesis and Antiproliferative Screening Of Novel Analogs of Regioselectively Demethylated Colchicine and Thiocolchicine

    Article • Molecules, March 2020, MDPI AG

    Prof. Joanna Wietrzyk

  58. Synthesis, CYP24A1-Dependent Metabolism and Antiproliferative Potential against Colorectal Cancer Cells of 1,25-Dihydroxyvitamin D2 Derivatives Modified at the Side Chain and the A-Ring

    Article • International Journal of Molecular Sciences, January 2020, MDPI AG

    Prof. Joanna Wietrzyk

  59. Application of TLC to Evaluate the Lipophilicity of Newly Synthesized Betulin Derivatives

    Article • Journal of Chromatographic Science, January 2020, Oxford University Press (OUP)

    Prof. Joanna Wietrzyk

  60. Divergent Effect of Tacalcitol (PRI-2191) on Th17 Cells in 4T1 Tumor Bearing Young and Old Ovariectomized Mice

    Article • Aging and Disease, January 2020, Aging and Disease

    Prof. Joanna Wietrzyk

  61. Assessment of the in vitro controlled release for some polymeric nanocomposites loaded with different drugs

    Article • Egyptian Journal of Chemistry, January 2020, Egypts Presidential Specialized Council for Education and Scientific Research

    Prof. Joanna Wietrzyk

  62. The N’-Substituted Derivatives of 5-Chloro-3-Methylisothiazole-4-Carboxylic Acid Hydrazide with Antiproliferative Activity

    Article • Molecules, December 2019, MDPI AG

    Prof. Joanna Wietrzyk

  63. The influence of a single and double biotinylation of xanthohumol on its anticancer activity

    Article • Acta Biochimica Polonica, December 2019, Frontiers

    Prof. Joanna Wietrzyk

  64. The influence of acupuncture TENS currents on the proliferation of cancer cells tested in vitro

    Article • Rehabilitacja Medyczna, December 2019, Index Copernicus

    Prof. Joanna Wietrzyk

  65. Synthesis, biological evaluation and molecular docking studies of new amides of 4-bromothiocolchicine as anticancer agents

    Article • Bioorganic & Medicinal Chemistry, December 2019, Elsevier

    Prof. Joanna Wietrzyk

  66. Design, synthesis and antiproliferative activity against human cancer cell lines of novel benzo-, benzofuro-, azolo- and thieno-1,3-thiazinone resorcinol hybrids

    Article • Arabian Journal of Chemistry, December 2019, Scientific Scholar

    Prof. Joanna Wietrzyk

  67. IL-33 – positive or negative role in cancer progression?

    Article • Postępy Higieny i Medycyny Doświadczalnej, November 2019, De Gruyter

    Prof. Joanna Wietrzyk

  68. Insulin enhancement of the antitumor activity of chemotherapeutic agents in colorectal cancer is linked with downregulating PIK3CA and GRB2

    Article • Scientific Reports, November 2019, Springer Science + Business Media

    Prof. Joanna Wietrzyk

  69. De‑O‑acylated lipooligosaccharide of E.�coli B reduces the number of metastatic foci via downregulation of myeloid cell activity

    Article • Oncology Reports, November 2019, Spandidos Publications

    Prof. Joanna Wietrzyk

  70. EGFR-targeted immunoliposomes as a selective delivery system of simvastatin, with potential use in treatment of triple-negative breast cancers

    Article • International Journal of Pharmaceutics, October 2019, Elsevier

    Prof. Joanna Wietrzyk

  71. Differential response of lung cancer cell lines to vitamin D derivatives depending on EGFR, KRAS, p53 mutation status and VDR polymorphism

    Article • The Journal of Steroid Biochemistry and Molecular Biology, October 2019, Elsevier

    Prof. Joanna Wietrzyk

  72. The 5-hydrazino-3-methylisothiazole-4-carboxylic acid, its new 5-substituted derivatives and their antiproliferative activity

    Article • Bioorganic Chemistry, October 2019, Elsevier

    Prof. Joanna Wietrzyk

  73. Synthesis, antiproliferative activity, and molecular docking studies of 4‐chlorothiocolchicine analogues

    Article • Chemical Biology & Drug Design, September 2019, Wiley

    Prof. Joanna Wietrzyk

  74. Biological effects of aromatic bis[aminomethylidenebis(phosphonic)] acids in osteoclast precursors in vitro

    Article • Chemical Biology & Drug Design, August 2019, Wiley

    Prof. Joanna Wietrzyk

  75. 3,4-dimethoxybenzyl isothiocyanate enhances doxorubicin efficacy in LoVoDX doxorubicin-resistant colon cancer and attenuates its toxicity in vivo

    Article • Life Sciences, August 2019, Elsevier

    Prof. Joanna Wietrzyk

  76. Discovery of tropinone-thiazole derivatives as potent caspase 3/7 activators, and noncompetitive tyrosinase inhibitors with high antiproliferative activity: Rational design, one-pot tricomponent synthesis, and lipophilicity determination

    Article • European Journal of Medicinal Chemistry, August 2019, Elsevier

    Prof. Joanna Wietrzyk

  77. Influence of amide versus ester linkages on the anticancer properties of the new flavone–biotin conjugates

    Article • Zeitschrift für Naturforschung C, July 2019, De Gruyter

    Prof. Joanna Wietrzyk

  78. Antiproliferative activity of ester derivatives of monensin A at the C‐1 and C‐26 positions

    Article • Chemical Biology & Drug Design, July 2019, Wiley

    Prof. Joanna Wietrzyk

  79. Structure–Antioxidant–Antiproliferative Activity Relationships of Natural C7 and C7–C8 Hydroxylated Flavones and Flavanones

    Article • Antioxidants, July 2019, MDPI AG

    Prof. Joanna Wietrzyk

  80. Structural Modifications of Nature-Inspired Indoloquinolines: A Mini Review of Their Potential Antiproliferative Activity

    Article • Molecules, June 2019, MDPI AG

    Dr Tsutomu Inokuchi, Prof. Joanna Wietrzyk

  81. New phosphate derivatives of betulin as anticancer agents: Synthesis, crystal structure, and molecular docking study

    Article • Bioorganic Chemistry, June 2019, Elsevier

    Prof. Joanna Wietrzyk

  82. Tacalcitol increases the sensitivity of colorectal cancer cells to 5-fluorouracil by downregulating the thymidylate synthase

    Article • The Journal of Steroid Biochemistry and Molecular Biology, June 2019, Elsevier

    Prof. Joanna Wietrzyk

  83. Similarities and differences in d6 low-spin ruthenium, rhodium and iridium half-sandwich complexes: synthesis, structure, cytotoxicity and interaction with biological targets

    Article • JBIC Journal of Biological Inorganic Chemistry, May 2019, Springer Science + Business Media

    Prof. Joanna Wietrzyk

  84. Platinum(II) and copper(II) complexes of 7-azaindole-3-carboxaldehyde: crystal structures, IR and Raman spectra, DFT calculations and in vitro antiproliferative activity of the platinum(II) complex

    Article • Inorganica Chimica Acta, May 2019, Elsevier

    Prof. Joanna Wietrzyk

  85. Biological Activity and In Silico Study of 3-Modified Derivatives of Betulin and Betulinic Aldehyde

    Article • International Journal of Molecular Sciences, March 2019, MDPI AG

    Prof. Joanna Wietrzyk

  86. Triazene salts: Design, synthesis, ctDNA interaction, lipophilicity determination, DFT calculation, and antiproliferative activity against human cancer cell lines

    Article • Saudi Pharmaceutical Journal, March 2019, Springer Science + Business Media

    Prof. Joanna Wietrzyk

  87. Calcitriol Analogues Decrease Lung Metastasis but Impair Bone Metabolism in Aged Ovariectomized Mice Bearing 4T1 Mammary Gland Tumours

    Article • Aging and Disease, January 2019, Aging and Disease

    Prof. Joanna Wietrzyk

  88. Temporal inhibition of mouse mammary gland cancer metastasis by CORM-A1 and DETA/NO combination therapy

    Article • Theranostics, January 2019, Ivyspring International Publisher

    Prof. Joanna Wietrzyk

  89. Spectroscopic, structural and anticancer activity studies of (−)-cytisine halogenated N-benzyl derivatives

    Article • Journal of Molecular Structure, January 2019, Elsevier

    Prof. Joanna Wietrzyk

  90. Synthesis and electrochemical, spectral, and biological evaluation of novel 9,10-anthraquinone derivatives containing piperidine unit as potent antiproliferative agents

    Article • Journal of Molecular Structure, January 2019, Elsevier

    Prof. Joanna Wietrzyk

  91. Synthesis, crystal structure, 1H, 13C and 15N NMR studies, and biological evaluation of a new amidrazone-derived Au(III) complex

    Article • Journal of Molecular Structure, January 2019, Elsevier

    Prof. Joanna Wietrzyk

  92. Steroid hormone calcitriol and its analog tacalcitol inhibit miR-125b expression in a human breast cancer MCF-7 cell line

    Article • Steroids, January 2019, Elsevier

    Prof. Joanna Wietrzyk

  93. DESIGN, SYNTHESIS AND ANALYSIS OF ANTICANCER ACTIVITY OF NEW SAR-BASED S16020 DERIVATIVES

    Article • Acta Poloniae Pharmaceutica - Drug Research, December 2018, Polish Pharmaceutical Society

    Dr Tomasz Gebarowski, Prof. Joanna Wietrzyk

  94. Synthesis, antiproliferative activity and molecular docking of thiocolchicine urethanes

    Article • Bioorganic Chemistry, December 2018, Elsevier

    Prof. Joanna Wietrzyk

  95. Synthesis and Biological Evaluation of Novel Triple-Modified Colchicine Derivatives as Potent Tubulin-Targeting Anticancer Agents

    Article • Cells, November 2018, MDPI AG

    Prof. Joanna Wietrzyk

  96. Highly Cancer Selective Antiproliferative Activity of Natural Prenylated Flavonoids

    Article • Molecules, November 2018, MDPI AG

    Prof. Joanna Wietrzyk

  97. Antiproliferative Activity and Molecular Docking of Novel Double-Modified Colchicine Derivatives

    Article • Cells, November 2018, MDPI AG

    Prof. Joanna Wietrzyk

  98. Picoplatin-based complexes with the bioactive orotate and 5-fluoroorotate ligands: Synthesis, DFT calculations, structure, spectroscopic characterization and in vitro cytotoxicity

    Article • Journal of Molecular Structure, November 2018, Elsevier

    Prof. Joanna Wietrzyk

  99. Synthesis, physicochemical and theoretical studies on new rhodium and ruthenium dimers. Relationship between structure and cytotoxic activity

    Article • Polyhedron, November 2018, Elsevier

    Prof. Joanna Wietrzyk

  100. Plant lyophilisate carrying S-HBsAg as an oral booster vaccine against HBV

    Article • Vaccine, October 2018, Elsevier

    Prof. Joanna Wietrzyk

  101. New mono- and dinuclear complexes of 7-azaindole-3-carboxaldehyde with palladium(II): crystal structure, IR and Raman spectra, DFT calculations and in vitro antiproliferative activity

    Article • Polyhedron, October 2018, Elsevier

    Prof. Joanna Wietrzyk

  102. Combination Therapy with DETA/NO and Clopidogrel Inhibits Metastasis in Murine Mammary Gland Cancer Models via Improved Vasoprotection

    Article • Molecular Pharmaceutics, September 2018, American Chemical Society (ACS)

    Prof. Joanna Wietrzyk

  103. Triazole Biheterocycles from Cinchona Alkaloids: Coordination and Antiproliferative Properties

    Article • ChemistrySelect, August 2018, Wiley

    Prof. Joanna Wietrzyk

  104. Synthesis, Characterization, and In Vitro Cancer Cell Growth Inhibition Evaluation of Novel Phosphatidylcholines with Anisic and Veratric Acids

    Article • Molecules, August 2018, MDPI AG

    Prof. Joanna Wietrzyk

  105. Nitric oxide deficiency and endothelial–mesenchymal transition of pulmonary endothelium in the progression of 4T1 metastatic breast cancer in mice

    Article • Breast Cancer Research, August 2018, Springer Science + Business Media

    Prof. Joanna Wietrzyk

  106. Biological activity of doubly modified salinomycin analogs – Evaluation in vitro and ex vivo

    Article • European Journal of Medicinal Chemistry, August 2018, Elsevier

    Prof. Joanna Wietrzyk

  107. Phosphorus-containing isothiocyanate-derived mercapturic acids as a useful alternative for parental isothiocyanates in experimental oncology

    Article • Bioorganic & Medicinal Chemistry Letters, August 2018, Elsevier

    Prof. Joanna Wietrzyk

  108. Calcitriol and Its Analogs Establish the Immunosuppressive Microenvironment That Drives Metastasis in 4T1 Mouse Mammary Gland Cancer

    Article • International Journal of Molecular Sciences, July 2018, MDPI AG

    Prof. Joanna Wietrzyk

  109. Biotinylated xanthohumol: synthesis and <em>in vitro</em> biological evaluation for anticancer therapy

    Article • July 2018, MDPI AG

    Prof. Joanna Wietrzyk

  110. The Antiproliferative Activity and Molecular Docking studies of some sulfonamides against cancer cell lines compared to normal cells

    Article • Egyptian Journal of Chemistry, June 2018, Egypts Presidential Specialized Council for Education and Scientific Research

    Prof. Joanna Wietrzyk

  111. Synthesis and biological activity of novel benzoazoles, benzoazines and other analogs functionalized by 2,4-dihydroxyphenyl moiety

    Article • Research on Chemical Intermediates, May 2018, Springer Science + Business Media

    Prof. Joanna Wietrzyk

  112. Alterations in NO- and PGI2- dependent function in aorta in the orthotopic murine model of metastatic 4T1 breast cancer: relationship with pulmonary endothelial dysfunction and systemic inflammation

    Article • BMC Cancer, May 2018, Springer Science + Business Media

    Prof. Joanna Wietrzyk

  113. Discovering simple phenylboronic acid and benzoxaborole derivatives for experimental oncology – phase cycle-specific inducers of apoptosis in A2780 ovarian cancer cells

    Article • Investigational New Drugs, May 2018, Springer Science + Business Media

    Prof. Joanna Wietrzyk

  114. One-pot synthesis and antiproliferative activity of novel double-modified derivatives of the polyether ionophore monensin A

    Article • Chemical Biology & Drug Design, May 2018, Wiley

    Prof. Joanna Wietrzyk

  115. Efficient glycosylation of natural Danshensu and its enantiomer by sugar and 2-deoxy sugar donors

    Article • Carbohydrate Research, May 2018, Elsevier

    Prof. Joanna Wietrzyk

  116. Cyclo(Pro-DOPA), a third identified bioactive metabolite produced by Streptomyces sp. 8812

    Article • The Journal of Antibiotics, April 2018, Springer Science + Business Media

    Prof. Joanna Wietrzyk

  117. Cell Density-Dependent Cytological Stage Profile and Its Application for a Screen of Cytostatic Agents Active Toward Leukemic Stem Cells

    Article • Stem Cells and Development, April 2018, Mary Ann Liebert Inc

    Prof. Joanna Wietrzyk

  118. Synthesis and Antiproliferative Activity of Minor Hops Prenylflavonoids and New Insights on Prenyl Group Cyclization

    Article • Molecules, March 2018, MDPI AG

    Prof. Joanna Wietrzyk

  119. Dual antiplatelet therapy with clopidogrel and aspirin increases mortality in 4T1 metastatic breast cancer-bearing mice by inducing vascular mimicry in primary tumour

    Article • Oncotarget, March 2018, Impact Journals, LLC

    Prof. Joanna Wietrzyk

  120. Synthesis, structure, DNA binding and anticancer activity of mixed ligand ruthenium(II) complex

    Article • Journal of Molecular Structure, March 2018, Elsevier

    Prof. Joanna Wietrzyk

  121. Synthesis, molecular docking, ctDNA interaction, DFT calculation and evaluation of antiproliferative and anti-Toxoplasma gondii activities of 2,4-diaminotriazine-thiazole derivatives

    Article • Medicinal Chemistry Research, February 2018, Springer Science + Business Media

    Prof. Joanna Wietrzyk

  122. Novel (S )-1,3,4,12a-tetrahydropyrazino[2,1- c ][1,4]benzodiazepine-6,12(2 H ,11 H )-dione derivatives: Selective inhibition of MV-4-11 biphenotypic B myelomonocytic leukemia cells’ growth is accompanied by reactive oxygen species overproduction and ap...

    Article • Bioorganic & Medicinal Chemistry Letters, February 2018, Elsevier

    Prof. Joanna Wietrzyk

  123. In search of new anticancer drug – Dimethylsulfoxide ruthenium(III) complex with bulky triazolopyrimidine derivative and preliminary studies towards understanding the mode of action

    Article • Polyhedron, February 2018, Elsevier

    Prof. Joanna Wietrzyk

  124. Synthesis and biological evaluation of acyl derivatives of hydroxyflavones as potent antiproliferative agents against drug resistance cell lines

    Article • Zeitschrift für Naturforschung C, January 2018, De Gruyter

    Prof. Joanna Wietrzyk

  125. Uptake and bioreactivity of charged chitosan-coated superparamagnetic nanoparticles as promising contrast agents for magnetic resonance imaging

    Article • Nanomedicine Nanotechnology Biology and Medicine, January 2018, Elsevier

    Prof. Joanna Wietrzyk, Professor Szczepan Zapotoczny

  126. Synthesis and biological evaluation of phosphatidylcholines with cinnamic and 3-methoxycinnamic acids with potent antiproliferative activity

    Article • RSC Advances, January 2018, Royal Society of Chemistry

    Prof. Joanna Wietrzyk

  127. Vitamin�D derivatives potentiate the anticancer and anti-angiogenic activity of tyrosine kinase inhibitors in combination with cytostatic drugs in an A549 non-small cell lung cancer model

    Article • International Journal of Oncology, December 2017, Spandidos Publications

    Prof. Joanna Wietrzyk

  128. Design, Synthesis, and Evaluation of ω-(Isothiocyanato)alkylphosphinates and Phosphine Oxides as Antiproliferative Agents

    Article • ChemMedChem, December 2017, Wiley

    Prof. Joanna Wietrzyk

  129. Clopidogrel in a combined therapy with anticancer drugs—effect on tumor growth, metastasis, and treatment toxicity: Studies in animal models

    Article • PLOS One, December 2017, PLOS

    Prof. Joanna Wietrzyk

  130. Synthesis and In Vitro Antiproliferative Activity of 11-Substituted Neocryptolepines with a Branched ω-Aminoalkylamino Chain

    Article • Molecules, November 2017, MDPI AG

    Prof. Joanna Wietrzyk

  131. Unfavorable effect of calcitriol and its low-calcemic analogs on metastasis of 4T1 mouse mammary gland cancer

    Article • International Journal of Oncology, November 2017, Spandidos Publications

    Prof. Joanna Wietrzyk

  132. Molecular basis for the DNA damage induction and anticancer activity of asymmetrically substituted anthrapyridazone PDZ-7

    Article • Oncotarget, October 2017, Impact Journals, LLC

    Prof. Joanna Wietrzyk, Dr. Paola Perego

  133. An efficient synthesis of indolo[2,3-b]quinoline guanidine derivatives with their in vitro and in vivo study

    Article • Medicinal Chemistry Research, September 2017, Springer Science + Business Media

    Prof. Joanna Wietrzyk

  134. Aminophosphinates against Helicobacter pylori ureolysis—Biochemical and whole-cell inhibition characteristics

    Article • PLOS One, August 2017, PLOS

    Łukasz Berlicki, Prof. Joanna Wietrzyk

  135. Methotrexate and epirubicin conjugates as potential antitumor drugs

    Article • Postępy Higieny i Medycyny Doświadczalnej, July 2017, De Gruyter

    Prof. Joanna Wietrzyk

  136. Rational design of dicarboxylato platinum(II) complexes with purine-mimetic ligands as novel anticancer agents

    Article • Journal of Inorganic Biochemistry, July 2017, Elsevier

    Prof. Joanna Wietrzyk

  137. Bivalent polyether ionophores: Synthesis and biological evaluation of C2-symmetric salinomycin dimers

    Article • Tetrahedron Letters, June 2017, Elsevier

    Prof. Joanna Wietrzyk

  138. Synthesis and evaluation of cytotoxic activity of conjugated linoleic acid derivatives (esters, alcohols, and their acetates) toward cancer cell lines

    Article • European Journal of Lipid Science and Technology, May 2017, Wiley

    Katarzyna Kempinska, Prof. Joanna Wietrzyk

  139. Novel phosphonate analogs of sulforaphane: Synthesis, in vitro and in vivo anticancer activity

    Article • European Journal of Medicinal Chemistry, May 2017, Elsevier

    Prof. Joanna Wietrzyk

  140. Magnesium cinnamate complex, [Mg(cinn)2(H2O)2]n; structural, spectroscopic, thermal, biological and pharmacokinetical characteristics

    Article • Journal of Molecular Structure, April 2017, Elsevier

    Prof. Joanna Wietrzyk

  141. New chiral Mannich adducts of di-tert-butylphenols and a bicyclic imine – Synthesis and antiproliferative activity

    Article • Tetrahedron, April 2017, Elsevier

    Prof. Joanna Wietrzyk

  142. The effects of 1,4-dimethylpyridine in metastatic prostate cancer in mice

    Article • BMC Cancer, March 2017, Springer Science + Business Media

    Prof. Joanna Wietrzyk

  143. Potent covalent inhibitors of bacterial urease identified by activity-reactivity profiling

    Article • Bioorganic & Medicinal Chemistry Letters, March 2017, Elsevier

    Łukasz Berlicki, Prof. Joanna Wietrzyk

  144. Isoprenoid-phospholipid conjugates as potential therapeutic agents: Synthesis, characterization and antiproliferative studies

    Article • PLOS One, February 2017, PLOS

    Prof. Joanna Wietrzyk

  145. Reaction of 3-Amino-1,2,4-Triazole with Diethyl Phosphite and Triethyl Orthoformate: Acid-Base Properties and Antiosteoporotic Activities of the Products

    Article • Molecules, February 2017, MDPI AG

    Prof. Joanna Wietrzyk

  146. Syntheses and antiproliferative activities of novel phosphatidylcholines containing dehydroepiandrosterone moieties

    Article • Steroids, February 2017, Elsevier

    Prof. Joanna Wietrzyk

  147. Differences in Antiproliferative Activity Between Salinomycin-AZT Conjugates Obtained via ‘Click’ and Esterification Reactions

    Article • Medicinal Chemistry, January 2017, Bentham Science Publishers

    Prof. Joanna Wietrzyk

  148. Robust oil-core nanocapsules with hyaluronate-based shells as promising nanovehicles for lipophilic compounds

    Article • Nanoscale, January 2017, Royal Society of Chemistry

    Professor Szczepan Zapotoczny, Prof. Joanna Wietrzyk

  149. Synthesis and biological evaluation of 4'-O-acetyl-isoxanthohumol and its analogues as antioxidant and antiproliferative agents

    Article • Acta Biochimica Polonica, January 2017, Polskie Towarzystwo Biochemiczne (Polish Biochemical Society)

    Prof. Joanna Wietrzyk

  150. Synthesis, crystal structure and cytotoxic activity of ruthenium(II) piano-stool complex with N,N-chelating ligand

    Article • Journal of Molecular Structure, December 2016, Elsevier

    Prof. Joanna Wietrzyk

  151. Heparin-binding copolymer reverses effects of unfractionated heparin, enoxaparin, and fondaparinux in rats and mice

    Article • Translational Research, November 2016, Elsevier

    Prof. Joanna Wietrzyk

  152. Molecular docking studies, biological and toxicity evaluation of dihydroisoquinoline derivatives as potential anticancer agents

    Article • Bioorganic & Medicinal Chemistry, November 2016, Elsevier

    Prof. Joanna Wietrzyk

  153. Antiangiogenic cancer treatment: The great discovery and greater complexity (Review)

    Article • International Journal of Oncology, September 2016, Spandidos Publications

    Prof. Joanna Wietrzyk

  154. New acetylenic derivatives of betulin and betulone, synthesis and cytotoxic activity

    Article • Medicinal Chemistry Research, September 2016, Springer Science + Business Media

    Prof. Joanna Wietrzyk

  155. Synthesis, structure and antiproliferative activity of chiral polyamines based on a 2-azanorbornane skeleton

    Article • Tetrahedron Asymmetry, September 2016, Elsevier

    Prof. Joanna Wietrzyk

  156. Thiazole-based nitrogen mustards: Design, synthesis, spectroscopic studies, DFT calculation, molecular docking, and antiproliferative activity against selected human cancer cell lines

    Article • Journal of Molecular Structure, September 2016, Elsevier

    Prof. Joanna Wietrzyk

  157. A novel canine B-cell leukaemia cell line. Establishment, characterisation and sensitivity to chemotherapeutics

    Article • Veterinary and Comparative Oncology, August 2016, Wiley

    Prof. Joanna Wietrzyk

  158. Synthesis and antiproliferative activity of some N′-substituted 2,4-dihydroxybenzothiohydrazides

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, July 2016, Taylor & Francis

    Prof. Joanna Wietrzyk

  159. 1-methylnicotinamide and its structural analog 1,4-dimethylpyridine for the prevention of cancer metastasis

    Article • Journal of Experimental & Clinical Cancer Research, July 2016, Springer Science + Business Media

    Prof. Joanna Wietrzyk

  160. Rapid biochemical profiling of endothelial dysfunction in diabetes, hypertension and cancer metastasis by hierarchical cluster analysis of Raman spectra

    Article • Journal of Raman Spectroscopy, July 2016, Wiley

    Prof. Joanna Wietrzyk

  161. Synthesis and Biological Evaluation of Novel Phosphatidylcholine Analogues Containing Monoterpene Acids as Potent Antiproliferative Agents

    Article • PLOS One, June 2016, PLOS

    Prof. Joanna Wietrzyk

  162. Dehalogenation Activity of Selected Fungi Towardδ-Iodo-γ-Lactone Derived fromtrans,trans-Farnesol

    Article • Chemistry & Biodiversity, April 2016, Wiley

    Prof. Joanna Wietrzyk

  163. The Toxicokinetic Profile of Dex40-GTMAC3—a Novel Polysaccharide Candidate for Reversal of Unfractionated Heparin

    Article • Frontiers in Pharmacology, March 2016, Frontiers

    Prof. Joanna Wietrzyk

  164. 3D Raman imaging of systemic endothelial dysfunction in the murine model of metastatic breast cancer

    Article • Analytical and Bioanalytical Chemistry, March 2016, Springer Science + Business Media

    Prof. Joanna Wietrzyk

  165. Synthesis, antiproliferative activity and molecular docking of Colchicine derivatives

    Article • Bioorganic Chemistry, February 2016, Elsevier

    Prof. Joanna Wietrzyk

  166. Oral Administration of Polymyxin B Modulates the Activity of Lipooligosaccharide E. coli B against Lung Metastases in Murine Tumor Models

    Article • PLOS One, February 2016, PLOS

    Prof. Joanna Wietrzyk

  167. Synthesis, structure and cytotoxic activity of acetylenic derivatives of betulonic and betulinic acids

    Article • Journal of Molecular Structure, February 2016, Elsevier

    Prof. Joanna Wietrzyk

  168. Indolo[2,3-b]quinoline derivatives as novel promising antitumor agents

    Article • January 2016, PeerJ

    Prof. Joanna Wietrzyk

  169. Synthesis and biological activity of diisothiocyanate-derived mercapturic acids

    Article • Bioorganic & Medicinal Chemistry Letters, January 2016, Elsevier

    Prof. Joanna Wietrzyk

  170. Synthesis of 4-(4-methylidene-4H-3,1-benzothiazin-2-yl)benzene1,3-diols and their antiproliferative activity against human cancer cell lines

    Article • Russian Journal of Bioorganic Chemistry, January 2016, Pleiades Publishing Ltd

    Prof. Joanna Wietrzyk

  171. Synthesis and Investigation of the Antitumor Properties of Novel, Bicyclic Furopyrimidine, Pyrrolopyrimidine and Pyrimidopyridazine Nucleoside Analogues

    Article • Synthesis, December 2015, Thieme Publishing Group

    Prof. Joanna Wietrzyk

  172. Slow-release nanopolymeric biodegradable composites holding doxorubicin and evaluation its antiproliferative potency on cancer

    Article • Polymer Composites, December 2015, Wiley

    Professor Aman Ibrahim Khalaf, Professor abdelmohsen m soliman, Prof. Joanna Wietrzyk

  173. N-Arylaminomethylenebisphosphonates Bearing Fluorine Atoms: Synthesis and Antiosteoporotic Activity

    Article • Phosphorus Sulfur and Silicon and the Related Elements, December 2015, Taylor & Francis

    Prof. Joanna Wietrzyk

  174. Vitamin D Analogs Potentiate the Antitumor Effect of Imatinib Mesylate in a Human A549 Lung Tumor Model

    Article • International Journal of Molecular Sciences, November 2015, MDPI AG

    Prof. Joanna Wietrzyk

  175. The synthesis of indolo[2,3-b]quinoline derivatives with a guanidine group: Highly selective cytotoxic agents

    Article • European Journal of Medicinal Chemistry, November 2015, Elsevier

    Prof. Joanna Wietrzyk

  176. Bicyclic cytarabine analogues: synthesis and investigation of antitumor properties of novel, 6-aryl- and 6-alkyl-3H-pyrrolo[2,3-d]pyrimidin-2(7H)-one arabinosides

    Article • Tetrahedron, November 2015, Elsevier

    Prof. Joanna Wietrzyk

  177. Antiproliferative Activity and in Vivo Toxicity of Double-Point Modified Analogs of 1,25-Dihydroxyergocalciferol

    Article • International Journal of Molecular Sciences, October 2015, MDPI AG

    Prof. Joanna Wietrzyk

  178. Anti-proliferative activity of Monensin and its tertiary amide derivatives

    Article • Bioorganic & Medicinal Chemistry Letters, October 2015, Elsevier

    Prof. Joanna Wietrzyk

  179. Synthesis and antiproliferative activity of new bioconjugates of Salinomycin with amino acid esters

    Article • Bioorganic & Medicinal Chemistry Letters, September 2015, Elsevier

    Prof. Joanna Wietrzyk

  180. Acetate platinum(II) compound with 5,7-ditertbutyl-1,2,4-triazolo[1,5-a]pyrimidine that overcomes cisplatin resistance: structural characterization,in vitrocytotoxicity, and kinetic studies

    Article • Journal of Coordination Chemistry, August 2015, Taylor & Francis

    Prof. Joanna Wietrzyk

  181. Endothelium and cancer metastasis: Perspectives for antimetastatic therapy

    Article • Pharmacological Reports, August 2015, Elsevier

    Prof. Joanna Wietrzyk

  182. Synthesis and Antiproliferative Activity of Silybin Conjugates with Salinomycin and Monensin

    Article • Chemical Biology & Drug Design, July 2015, Wiley

    Prof. Joanna Wietrzyk

  183. Synthesis and biological activity of salinomycin conjugates with floxuridine

    Article • European Journal of Medicinal Chemistry, March 2015, Elsevier

    Prof. Joanna Wietrzyk

  184. Antiproliferative Activity of Polyether Antibiotic -CinchonaAlkaloid Conjugates ObtainedviaClick Chemistry

    Article • Chemical Biology & Drug Design, February 2015, Wiley

    Prof. Joanna Wietrzyk

  185. Synthesis, antiproliferative and antibacterial evaluation of C-ring modified colchicine analogues

    Article • European Journal of Medicinal Chemistry, January 2015, Elsevier

    Prof. Joanna Wietrzyk

  186. Phosphatidylcholine with cis-9,trans-11 and trans-10,cis-12 Conjugated Linoleic Acid Isomers: Synthesis and Cytotoxic Studies

    Article • Australian Journal of Chemistry, January 2015, CSIRO Publishing

    Prof. Joanna Wietrzyk

  187. The Disulfide Analogues of Isophosphoramide Mustard for Anticancer Therapy

    Article • Letters in Drug Design & Discovery, December 2014, Bentham Science Publishers

    Prof. Joanna Wietrzyk

  188. Cytotoxic malonate platinum(II) complexes with 1,2,4-triazolo[1,5- a ]pyrimidine derivatives: Structural characterization and mechanism of the suppression of tumor cell growth

    Article • Journal of Inorganic Biochemistry, December 2014, Elsevier

    Prof. Joanna Wietrzyk

  189. Synthesis, Anticancer and Antibacterial Activity of Salinomycin N-Benzyl Amides

    Article • Molecules, November 2014, MDPI AG

    Prof. Joanna Wietrzyk

  190. Design, Synthesis, and Biological Evaluation of Artemisinin-Indoloquinoline Hybrids as Potent Antiproliferative Agents

    Article • Molecules, November 2014, MDPI AG

    Prof. Joanna Wietrzyk, Dr Tsutomu Inokuchi

  191. An efficient process to directly convert 1-hydroxymethyl-3,5-dimethylpyrazole to Cd(ii) complexes via C–N bond creation: cytotoxicity and factors controlling the structures

    Article • RSC Advances, September 2014, Royal Society of Chemistry

    Prof. Joanna Wietrzyk

  192. Synthesis and In Vitro Antiproliferative Activity of Thiazole-Based Nitrogen Mustards: The Hydrogen Bonding Interaction between Model Systems and Nucleobases

    Article • Anti-Cancer Agents in Medicinal Chemistry, July 2014, Bentham Science Publishers

    Prof. Joanna Wietrzyk

  193. Bacteriophages displaying anticancer peptides in combined antibacterial and anticancer treatment

    Article • Future Microbiology, July 2014, Future Medicine

    Prof. Joanna Wietrzyk

  194. Vitamin D analogs combined with 5-fluorouracil in human HT-29 colon cancer treatment

    Article • Oncology Reports, June 2014, Spandidos Publications

    Prof. Joanna Wietrzyk

  195. Synthesis and antiproliferative activity in vitro of new 2-aminobenzimidazole derivatives. Reaction of 2-arylideneaminobenzimidazole with selected nitriles containing active methylene group

    Article • Open Chemistry, May 2014, De Gruyter

    Prof. Joanna Wietrzyk

  196. Hydroxyethyl starch as an effective methotrexate carrier in anticancer therapy

    Article • Pharmacology Research & Perspectives, May 2014, Wiley

    Dr Tomasz Marek Goszczyński, Prof. Joanna Wietrzyk

  197. Searching for new derivatives of neocryptolepine: Synthesis, antiproliferative, antimicrobial and antifungal activities

    Article • European Journal of Medicinal Chemistry, May 2014, Elsevier

    Professor Arkadiusz Kozubek, Prof. Joanna Wietrzyk

  198. Synthesis and in vitro cytotoxic effect of 6-amino-substituted 11H- and 11Me-indolo[3,2-c]quinolines

    Article • European Journal of Medicinal Chemistry, May 2014, Elsevier

    Prof. Joanna Wietrzyk

  199. Synthesis, antiproliferative and antibacterial activity of new amides of salinomycin

    Article • Bioorganic & Medicinal Chemistry Letters, April 2014, Elsevier

    Prof. Joanna Wietrzyk

  200. Synthesis, cytotoxicity and antibacterial activity of new esters of polyether antibiotic – salinomycin

    Article • European Journal of Medicinal Chemistry, April 2014, Elsevier

    Prof. Joanna Wietrzyk

  201. Efficient Human Breast Cancer Xenograft Regression after a Single Treatment with a Novel Liposomal Formulation of Epirubicin Prepared Using the EDTA Ion Gradient Method

    Article • PLOS One, March 2014, PLOS

    Professor Arkadiusz Kozubek, Prof. Joanna Wietrzyk

  202. Structural Factors Affecting Cytotoxic Activity of (E)-1-(Benzo[d ][1,3]oxathiol-6-yl)-3-phenylprop-2-en-1-one Derivatives

    Article • Chemical Biology & Drug Design, February 2014, Wiley

    Prof. Joanna Wietrzyk

  203. Freeze-Drying of Plant Tissue Containing HBV Surface Antigen for the Oral Vaccine against Hepatitis B

    Article • BioMed Research International, January 2014, Hindawi Publishing Corporation

    Prof. Joanna Wietrzyk

  204. Cancer – Could it be Cured? A Spontaneous Regression of Cancer, Cancer Energy Metabolism, Hyperglycemia-Hypoglycemia, Metformin, Warburg and Crabtree Effects and a New Perspective in Cancer Treatment

    Article • Journal of Cancer Science & Therapy, January 2014, OMICS Publishing Group

    Prof. Joanna Wietrzyk

  205. Crystal structure, infrared and EPR spectra and anticancer activity in vitro of the novel manganese(II) complexes of indolecarboxylic acids

    Article • Polyhedron, January 2014, Elsevier

    Prof. Joanna Wietrzyk

  206. Synthetic Access to Poly-Substituted 11H-Pyrido[3,2-a]carbazoles, a DNA-Intercalating Ellipticine Related Structure, and Their Antiproliferative Activity

    Article • Heterocycles, January 2014, CLOCKSS Archive

    Prof. Joanna Wietrzyk

  207. Design, synthesis, and in vitro cancer cell growth inhibition evaluation and antimalarial testing of trioxanes installed in cyclic 2-enoate substructures

    Article • European Journal of Medicinal Chemistry, November 2013, Elsevier

    Prof. Joanna Wietrzyk, Dr Tsutomu Inokuchi

  208. Synthesis and Biological Activity of Diastereomeric and Geometric Analogs of Calcipotriol, PRI-2202 and PRI-2205, Against Human HL-60 Leukemia and MCF-7 Breast Cancer Cells

    Article • Cancers, October 2013, MDPI AG

    Prof. Joanna Wietrzyk

  209. Synthesis, characterization and antiproliferative activity of β-aryl-δ-iodo-γ-lactones

    Article • Journal of Molecular Structure, September 2013, Elsevier

    Professor Krzysztof Wozniak, Prof. Joanna Wietrzyk

  210. One-pot synthesis and cytotoxicity studies of new Mannich base derivatives of polyether antibiotic—Lasalocid acid

    Article • Bioorganic & Medicinal Chemistry Letters, September 2013, Elsevier

    Prof. Joanna Wietrzyk

  211. Novel Genistein Derivatives Induce Cell Death and Cell Cycle Arrest Through Different Mechanisms

    Article • Nutrition and Cancer, August 2013, Taylor & Francis

    Prof. Joanna Wietrzyk

  212. Corrigendum to “The antileukemic activity of modified fibrinogen–methotrexate conjugate” [Biochim. Biophys. Acta 1830 (2013) 2526–2530]

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, August 2013, Elsevier

    Prof. Joanna Wietrzyk

  213. Synthesis of new pyrimidine derivatives and their antiproliferative activity against selected human cancer cell lines

    Article • Research on Chemical Intermediates, June 2013, Springer Science + Business Media

    Prof. Joanna Wietrzyk

  214. Vitamin D analogs enhance the anticancer activity of 5-fluorouracil in an in vivomouse colon cancer model

    Article • BMC Cancer, June 2013, Springer Science + Business Media

    Prof. Joanna Wietrzyk

  215. Synthesis, Structure and Cytotoxic Activity of New Acetylenic Derivatives of Betulin

    Article • Molecules, April 2013, MDPI AG

    Prof. Joanna Wietrzyk

  216. Antioxidant and antiproliferative activity of glycosides obtained by biotransformation of xanthohumol

    Article • Bioorganic & Medicinal Chemistry Letters, April 2013, Elsevier

    Prof. Joanna Wietrzyk

  217. Fungal metabolites of xanthohumol with potent antiproliferative activity on human cancer cell lines in vitro

    Article • Bioorganic & Medicinal Chemistry, April 2013, Elsevier

    Prof. Joanna Wietrzyk

  218. Synthesis and Cytotoxic Activity of New Betulin and Betulinic Acid Esters with Conjugated Linoleic Acid (CLA)

    Article • Natural Product Communications, April 2013, SAGE Publications

    Prof. Joanna Wietrzyk

  219. The antileukemic activity of modified fibrinogen–methotrexate conjugate

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, March 2013, Elsevier

    Prof. Joanna Wietrzyk

  220. Structure–activity relationship disturbed by a solvolytic process: Study on the [Cu(II)-4-nitropyridine N-oxide derivative] system

    Article • Polyhedron, February 2013, Elsevier

    Prof. Joanna Wietrzyk

  221. In vitro antiproliferative activity of 11-aminoalkylamino-substituted 5H-indolo[2,3-b]quinolines; improving activity of neocryptolepines by installation of ester substituent

    Article • Medicinal Chemistry Research, January 2013, Springer Science + Business Media

    Dr Tsutomu Inokuchi, Prof. Joanna Wietrzyk

  222. Synthesis of Phosphatidylcholine with Conjugated Linoleic Acid and Studies on Its Cytotoxic Activity

    Article • Australian Journal of Chemistry, January 2013, CSIRO Publishing

    Prof. Joanna Wietrzyk

  223. X-ray crystallographic, FT-IR and NMR studies as well as anticancer and antibacterial activity of the salt formed between ionophore antibiotic Lasalocid acid and amines

    Article • Journal of Molecular Structure, January 2013, Elsevier

    Prof. Joanna Wietrzyk

  224. Antiproliferative activity of salinomycin and its derivatives

    Article • Bioorganic & Medicinal Chemistry Letters, December 2012, Elsevier

    Prof. Joanna Wietrzyk

  225. Synthesis and in vitro antiproliferative activity of new 11-aminoalkylamino-substituted chromeno[2,3-b]indoles

    Article • European Journal of Medicinal Chemistry, December 2012, Elsevier

    Prof. Joanna Wietrzyk, Dr Tsutomu Inokuchi

  226. Phenolic profile, antioxidant and antiproliferative activity of black and red currants (Ribes spp.) from organic and conventional cultivation

    Article • International Journal of Food Science & Technology, November 2012, Oxford University Press (OUP)

    Prof. Joanna Wietrzyk

  227. New derivatives of 11-methyl-6-[2-(dimethylamino)ethyl]-6H-indolo[2,3-b]quinoline as cytotoxic DNA topoisomerase II inhibitors

    Article • Bioorganic & Medicinal Chemistry Letters, October 2012, Elsevier

    Prof. Joanna Wietrzyk

  228. Structure-cytotoxicity relationship for different types of mononuclear platinum(II) complexes with 5,7-ditertbutyl-1,2,4-triazolo[1,5-a]pyrimidine

    Article • Journal of Inorganic Biochemistry, October 2012, Elsevier

    Prof. Joanna Wietrzyk

  229. Convenient syntheses of novel 1-isothiocyano-alkylphosphonate diphenyl ester derivatives with potential biological activity

    Article • Tetrahedron Letters, October 2012, Elsevier

    Prof. Joanna Wietrzyk

  230. siRNA-mediated silencing of integrin β3 expression inhibits the metastatic potential of B16 melanoma cells

    Article • Oncology Reports, August 2012, Spandidos Publications

    Prof. Joanna Wietrzyk

  231. Synthesis and in vitro antiproliferative activity of new 11-aminoalkylamino-substituted 5H- and 6H-indolo[2,3-b]quinolines; structure–activity relationships of neocryptolepines and 6-methyl congeners

    Article • Bioorganic & Medicinal Chemistry, August 2012, Elsevier

    Prof. Joanna Wietrzyk

  232. Synthesis and Biological Evaluation of New Amino Acid and Dipeptide Derivatives of Neocryptolepine as Anticancer Agents

    Article • Journal of Medicinal Chemistry, May 2012, American Chemical Society (ACS)

    Prof. Joanna Wietrzyk

  233. One-Pot Synthesis of New (1,3-Thiazolo[5,4-b]pyridin-2-yl)benzenediols and Their Antiproliferative Activities against Human Cancer Cell Lines

    Article • Chemistry & Biodiversity, January 2012, Wiley

    Prof. Joanna Wietrzyk

  234. The in-vitro antiproliferative effect of PRI-2191 and imatinib applied in combined treatment with cisplatin, idarubicin, or docetaxel on human leukemia cells

    Article • Anti-Cancer Drugs, January 2012, Wolters Kluwer Health

    Prof. Joanna Wietrzyk

  235. Synthesis and biological activity of novel 4- and 6-(1-alkyl/aryl-1H-benzimidazol-2-yl)benzene-1,3-diols

    Article • Monatshefte für Chemie - Chemical Monthly, October 2011, Springer Science + Business Media

    Prof. Joanna Wietrzyk

  236. Synthesis and cytotoxicity studies of bifunctional hybrids of nitrogen mustards with potential enzymes inhibitors based on melamine framework

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, September 2011, Taylor & Francis

    Prof. Joanna Wietrzyk

  237. Synthesis and antiproliferative activity of novel α- and β-dialkoxyphosphoryl isothiocyanates

    Article • Bioorganic & Medicinal Chemistry Letters, August 2011, Elsevier

    Prof. Joanna Wietrzyk

  238. Systematic coordination chemistry and cytotoxicity of copper(II) complexes with methyl substituted 4-nitropyridine N-oxides

    Article • Journal of Inorganic Biochemistry, August 2011, Elsevier

    Prof. Joanna Wietrzyk

  239. HSAB principle and nickel(II) ion reactivity towards 1-methyhydantoin

    Article • Polyhedron, August 2011, Elsevier

    Prof. Joanna Wietrzyk

  240. Microbial transformation of (+)-nootkatone and the antiproliferative activity of its metabolites

    Article • Bioorganic & Medicinal Chemistry, April 2011, Elsevier

    Prof. Joanna Wietrzyk

  241. Synthesis and characterization of chloro-bis(quinoline-2-carboxylato-κ2N,O)gallium(III)

    Article • Journal of Coordination Chemistry, March 2011, Taylor & Francis

    Prof. Joanna Wietrzyk

  242. Simple phosphonic inhibitors of human neutrophil elastase

    Article • Bioorganic & Medicinal Chemistry Letters, March 2011, Elsevier

    Prof. Joanna Wietrzyk

  243. Synthesis of a Natural γ-Butyrolactone from Nerylacetone by Acremonium roseum and Fusarium oxysporum Cultures

    Article • Natural Product Communications, March 2011, SAGE Publications

    Prof. Joanna Wietrzyk

  244. Silver(I) complexes with hydantoins and allantoin☆Synthesis, crystal and molecular structure, cytotoxicity and pharmacokinetics

    Article • Journal of Inorganic Biochemistry, January 2011, Elsevier

    Prof. Joanna Wietrzyk

  245. Synthetic conjugates of genistein affecting proliferation and mitosis of cancer cells

    Article • Bioorganic & Medicinal Chemistry, January 2011, Elsevier

    Prof. Joanna Wietrzyk

  246. Anticancer activity of the Uncaria tomentosa (Willd.) DC. preparations with different oxindole alkaloid composition

    Article • Phytomedicine, December 2010, Elsevier

    Prof. Joanna Wietrzyk

  247. Synthesis and in vitro antiproliferative activity of novel (4-chloro- and 4-acyloxy-2-butynyl)thioquinolines

    Article • Medicinal Chemistry Research, November 2010, Springer Science + Business Media

    Prof. Joanna Wietrzyk

  248. Antitumor properties of (5E,7E) analogs of vitamin D3

    Article • The Journal of Steroid Biochemistry and Molecular Biology, July 2010, Elsevier

    Prof. Joanna Wietrzyk

  249. Mononuclear copper(II) nitrato complexes with methyl-substituted 4-nitropyridine N-oxide. Physicochemical and cytotoxic characteristics

    Article • Journal of Inorganic Biochemistry, February 2010, Elsevier

    Prof. Joanna Wietrzyk

  250. Organotin Compound Derived from 3-Hydroxy-2-formylpyridine Semicarbazone: Synthesis, Crystal Structure, and Antiproliferative Activity

    Article • Bioinorganic Chemistry and Applications, January 2010, Hindawi Publishing Corporation

    Prof. Joanna Wietrzyk

  251. The effects of staphylococcal bacteriophage lysates on cancer cells in vitro

    Article • Clinical and Experimental Medicine, September 2009, Springer Science + Business Media

    Prof. Joanna Wietrzyk

  252. Atypical calcium coordination number: Physicochemical study, cytotoxicity, DFT calculations and in silico pharmacokinetic characteristics of calcium caffeates

    Article • Journal of Inorganic Biochemistry, September 2009, Elsevier

    Prof. Joanna Wietrzyk

  253. Synthesis and biological properties of oxazolinodaunorubicin—a new derivative of daunorubicin with a modified daunosamine moiety

    Article • Investigational New Drugs, August 2009, Springer Science + Business Media

    Prof. Joanna Wietrzyk

  254. Synthesis, X-ray structure and antiproliferative activity of 3-benzylthio-4-propargylselenoquinoline

    Article • Medicinal Chemistry Research, May 2009, Springer Science + Business Media

    Prof. Joanna Wietrzyk

  255. The effect of bacteriophages T4 and HAP1 on in vitro melanoma migration

    Article • BMC Microbiology, January 2009, Springer Science + Business Media

    Prof. Joanna Wietrzyk

  256. Synthesis and antiproliferative activity in vitro of novel (2-butynyl)thioquinolines

    Article • Bioorganic & Medicinal Chemistry, September 2008, Elsevier

    Prof. Joanna Wietrzyk

  257. Synthesis and Anticancer Activity of New 1-Substituted-6H-pyrido[4,3-b]carbazole Derivatives

    Article • Archiv der Pharmazie, June 2008, Wiley

    Prof. Joanna Wietrzyk

  258. Toxicity and antitumor activity of the vitamin D analogs PRI-1906 and PRI-1907 in combined treatment with cyclophosphamide in a mouse mammary cancer model

    Article • Cancer Chemotherapy and Pharmacology, January 2008, Springer Science + Business Media

    Prof. Joanna Wietrzyk

  259. Investigating the antiproliferative activity of quinoline-5,8-diones and styrylquinolinecarboxylic acids on tumor cell lines

    Article • Bioorganic & Medicinal Chemistry Letters, November 2007, Elsevier

    Prof. Joanna Wietrzyk

  260. The Effect of Combined Treatment on Head and Neck Human Cancer Cell Lines With Novel Analogs of Calcitriol and Cytostatics

    Article • Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics, November 2007, Cognizant Communication Corporation

    Prof. Joanna Wietrzyk

  261. Antitumor Activity of Mannan–Methotrexate Conjugate In Vitro and In Vivo

    Article • Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics, September 2007, Cognizant Communication Corporation

    Prof. Joanna Wietrzyk

  262. Antitumor properties of diastereomeric and geometric analogs of vitamin D3

    Article • Anti-Cancer Drugs, April 2007, Wolters Kluwer Health

    Prof. Joanna Wietrzyk

  263. Hoc protein regulates the biological effects of T4 phage in mammals

    Article • Archives of Microbiology, February 2007, Springer Science + Business Media

    Prof. Joanna Wietrzyk

  264. Investigation of lipophilicity of anticancer-active thioquinoline derivatives

    Article • Biomedical Chromatography, January 2007, Wiley

    Prof. Joanna Wietrzyk

  265. Synthesis and Antiproliferative Activity in vitro of New Tricyclic 2-Thioxo-1 H ,3 H -imidazo[4,5-b]pyridine Derivatives

    Article • Phosphorus Sulfur and Silicon and the Related Elements, January 2007, Taylor & Francis

    Prof. Joanna Wietrzyk

  266. Synthesis of 5,6-Dimethyl-9-methoxy-1-phenyl-6H-pyrido[4,3-b]carbazole Derivatives and their Cytotoxic Activity

    Article • Archiv der Pharmazie, November 2005, Wiley

    Prof. Joanna Wietrzyk

  267. Activity of Bacteriophages in Murine Tumor Models Depends on the Route of Phage Administration

    Article • Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics, April 2005, Cognizant Communication Corporation

    Prof. Joanna Wietrzyk

  268. Synthesis, spectroscopical characterization and the biological activity in vitro of new platinum(II) complexes with imidazo[1,5-a]-1,3,5-triazine derivatives and dimethylsulfoxide

    Article • Inorganica Chimica Acta, March 2005, Elsevier

    Prof. Joanna Wietrzyk

  269. Magnesium deficiency inhibits primary tumor growth but favors metastasis in mice

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, December 2004, Elsevier

    Prof. Joanna Wietrzyk

  270. Toxicity and antineoplastic effect of (24R)-1,24-dihydroxyvitamin D3 (PRI-2191)

    Article • Steroids, September 2004, Elsevier

    Prof. Joanna Wietrzyk

  271. New analogues of laminin active fragment YIGSR: synthesis and biological activityin vitro andin vivo

    Article • Journal of Peptide Science, April 2004, Wiley

    Prof. Joanna Wietrzyk

  272. Synthesis and antiproliferative activity in vitro of 2-aminobenzimidazole derivatives

    Article • Il Farmaco, February 2004, Elsevier

    Prof. Joanna Wietrzyk

  273. Multinuclear NMR spectroscopy and antitumor activity of novel platinum(II) complexes with 5,7-disubstituted-1,2,4-triazolo[1,5- a ]pyrimidines

    Article • Journal of Inorganic Biochemistry, January 2004, Elsevier

    Prof. Joanna Wietrzyk

  274. Synthesis and Antiproliferative Activity in vitro of New 2-Thioxo-1H, 3H-imidazo[4,5-b]pyridine Derivatives

    Article • Phosphorus Sulfur and Silicon and the Related Elements, December 2003, Taylor & Francis

    Prof. Joanna Wietrzyk

  275. Synthesis and Cytostatic Activity of 4‐Substituted Derivatives of Isoxazolyltriazenes.

    Article • ChemInform, November 2003, Wiley

    Prof. Joanna Wietrzyk

  276. Article • Medical Immunology, January 2003, Springer Science + Business Media

    Prof. Joanna Wietrzyk

  277. Structure, Properties and Cytostatic Activity of Triorganotin (Aminoaryl)carboxylates

    Article • European Journal of Inorganic Chemistry, December 2002, Wiley

    Prof. Joanna Wietrzyk

  278. Synthesis and antiproliferative activity of side-chain unsaturated and homologated analogs of 1,25-dihydroxyvitamin D2

    Article • Steroids, August 2002, Elsevier

    Prof. Joanna Wietrzyk

  279. Rhodium(III) complexes with polypyridyls and pyrazole and their antitumor activity

    Article • Inorganica Chimica Acta, May 2002, Elsevier

    Prof. Joanna Wietrzyk

  280. Synthesis and antitumour activity of stereoisomers of 4-hydroperoxy derivatives of ifosfamide and its bromo analogue

    Article • Il Farmaco, April 2002, Elsevier

    Prof. Joanna Wietrzyk

  281. Synthesis and Antiproliferative Activity in Vitro of New Derivatives of 3-Aminopyrazolo[3,4-b]pyridine Part 1. Reaction of 3-Aminopyrazolo[3,4-b]pyridine with 1,3-, 1,4-Diketones and α,β-Unsaturated Ketones

    Article • Archiv der Pharmazie, July 2001, Wiley

    Prof. Joanna Wietrzyk

  282. Tetraacetatodirhodium(II) complexes with tris(methoxyphenyl)phosphines, their reactivity, structure, and antitumor activity

    Article • Canadian Journal of Chemistry, May 2001, Canadian Science Publishing

    Prof. Joanna Wietrzyk

  283. Synthesis and Antiproliferative Activityin Vitro of Novel 1,5-Benzodiazepines. Part II

    Article • Archiv der Pharmazie, January 2001, Wiley

    Prof. Joanna Wietrzyk

  284. Synthesis, Characterization and Antiproliferative Activity of the Co(II), Ni(II), Cu(II), Pd(II) and Pt(II) Complexes of 2-(4-Thiazolyl)Benzimidazole (Thiabendazole)

    Article • Metal-Based Drugs, January 2001, Hindawi Publishing Corporation

    Prof. Joanna Wietrzyk

  285. Antiproliferative activity in vitro of new malatoplatinum(II) complexes

    Article • Anti-Cancer Drugs, June 2000, Wolters Kluwer Health

    Prof. Joanna Wietrzyk

  286. Biological Activity In Vitro of Side-Chain Modified Analogues of Calcitriol

    Article • Current Pharmaceutical Design, May 2000, Bentham Science Publishers

    Prof. Joanna Wietrzyk

  287. Cytotoxic and antitumor effect of fibrinogen-methotrexate conjugate

    Article • Cancer Letters, February 2000, Elsevier

    Prof. Joanna Wietrzyk

  288. Metastatic potential and saccharide antigens expression of human colon cancer cells xenotransplanted into athymic nude mice

    Article • Folia Microbiologica, October 1998, Springer Science + Business Media

    Prof. Joanna Wietrzyk

  289. Article • Clinical & Experimental Metastasis, January 1998, Springer Science + Business Media

    Prof. Joanna Wietrzyk