All Stories

  1. High-Throughput Stationary 13C-Based Metabolic Flux Analysis of Pichia pastoris Strains

    Article • October 2025, Springer Science + Business Media

    Joan Albiol

  2. ID-MS-Based Quantitative Analysis of Metabolites in Pichia pastoris: A Step-by-Step Protocol

    Article • October 2025, Springer Science + Business Media

    Joan Albiol

  3. Metabolic engineering of Komagataella phaffii for enhanced 3-hydroxypropionic acid (3-HP) production from methanol

    Article • Journal of Biological Engineering, February 2025, Springer Science + Business Media

    Joan Albiol

  4. A Rewired NADPH-Dependent Redox Shuttle for Testing Peroxisomal Compartmentalization of Synthetic Metabolic Pathways in Komagataella phaffii

    Article • Microorganisms, December 2024, MDPI AG

    Joan Albiol

  5. A Rewired NADPH-Dependent Redox Shuttle for Testing Peroxisomal Compartmentalization of Synthetic Metabolic Pathways in Komagataella phaffii

    Article • December 2024, MDPI AG

    Joan Albiol

  6. Engineering the synthetic β-alanine pathway in Komagataella phaffii for conversion of methanol into 3-hydroxypropionic acid

    Article • Microbial Cell Factories, November 2023, Springer Science + Business Media

    Joan Albiol

  7. High throughput 13C-metabolic flux analysis of 3-hydroxypropionic acid producing Pichia pastoris reveals limited availability of acetyl-CoA and ATP due to tight control of the glycolytic flux

    Article • Microbial Cell Factories, June 2023, Springer Science + Business Media

    Joan Albiol

  8. Combining Metabolic Engineering and Multiplexed Screening Methods for 3-Hydroxypropionic Acid Production in Pichia pastoris

    Article • Frontiers in Bioengineering and Biotechnology, July 2022, Frontiers

    Joan Albiol

  9. Benchmarking recombinant Pichia pastoris for 3‐hydroxypropionic acid production from glycerol

    Article • Microbial Biotechnology, June 2021, Wiley

    Joan Albiol

  10. Continuous Cultivation as a Tool Toward the Rational Bioprocess Development With Pichia Pastoris Cell Factory

    Article • Frontiers in Bioengineering and Biotechnology, June 2020, Frontiers

    Joan Albiol

  11. Redox Engineering by Ectopic Overexpression of NADH Kinase in Recombinant Pichia pastoris ( Komagataella phaffii ): Impact on Cell Physiology and Recombinant Production of Secreted Proteins

    Article • Applied and Environmental Microbiology, March 2020, ASM Journals

    Joan Albiol

  12. Contextualized genome-scale model unveils high-order metabolic effects of the specific growth rate and oxygenation level in recombinant Pichia pastoris

    Article • Metabolic Engineering Communications, December 2019, Elsevier

    Joan Albiol

  13. Rational development of bioprocess engineering strategies for recombinant protein production in Pichia pastoris (Komagataella phaffii) using the methanol-free GAP promoter. Where do we stand?

    Article • New Biotechnology, November 2019, Elsevier

    Joan Albiol

  14. Glycerol metabolism of Pichia pastoris (Komagataella spp.) characterised by 13C-based metabolic flux analysis

    Article • New Biotechnology, May 2019, Elsevier

    Joan Albiol

  15. Deregulation of methanol metabolism reverts transcriptional limitations of recombinant Pichia pastoris (Komagataella spp) with multiple expression cassettes under control of the AOX1 promoter

    Article • Biotechnology and Bioengineering, February 2019, Wiley

    Joan Albiol

  16. Large expert-curated database for benchmarking document

    Article • Database, January 2019, Oxford University Press (OUP)

    Dr Daniel Prieto, Associate Professor James A.L. Brown, Professor Amanda G Thrift, Docent Kutty Selva Nandakumar, Professor Miguel Viveiros, MD Diego A. Valera-Cornejo, Dr Soroush Safaei, Dr Carmen San Martín, Piero Carninci, Dr Florian Rehfeldt, Dr Yoichi Watanabe, Kazuki Ide, Mr Alvin Wong, PD Dr. Adrian Meule, Dr Maurizio Petrelli, Dr Christine McGarrigle, Dr Tristan Reddan, Dr Nicola Roberts, Professor Stefan Lorkowski, Dr Cyrille Goarant, Dr Emma C Hobbs, Dr. Saurab Sharma, Ph.D., Dr Farid Rahimi, Prof. Iseult Lynch, Mirella Walker, Dr Luca Galluzzi, Sophie Ohlsson, Professor Tullio Florio, Dr Rabea A Gadelkareem, Dr Azubuike Christian Ukubuiwe, Prof Gajendra PS Raghava, Prof Jun Shen, Lubna Razak, ABHISHEKA BANSAL, Craig Billington, Dr Alejandro Lazo-Langner, Joan Albiol, MOURAD TAYEBI, Chuang Ma, Christine Toelzer , Dr. Kathrin Karsay, Professor Andrew M Beale, Professor Hugh James Byrne, Dr Ugo Marzocchi, Ana Nordberg, Martin Bartas, Natalia Echeverría, Dr Patricia M Graves, Dr Elvis A F Martis, Dr marco cascella, Dr. Giuseppe Lanza, Dr Michael Boah

  17. Metabolic flux balance analysis during lactate and glucose concomitant consumption in HEK293 cell cultures

    Article • Biotechnology and Bioengineering, December 2018, Wiley

    Joan Albiol

  18. Metabolic flux analysis and the NAD(P)H/NAD(P)+ ratios in chemostat cultures of Azotobacter vinelandii

    Article • Microbial Cell Factories, January 2018, Springer Science + Business Media

    Joan Albiol

  19. Fine-tuning the P. pastoris iMT1026 genome-scale metabolic model for improved prediction of growth on methanol or glycerol as sole carbon sources

    Article • Microbial Biotechnology, November 2017, Wiley

    Joan Albiol

  20. Increased dosage of AOX1 promoter-regulated expression cassettes leads to transcription attenuation of the methanol metabolism in Pichia pastoris

    Article • Scientific Reports, March 2017, Springer Science + Business Media

    Joan Albiol

  21. Genome-scale metabolic reconstruction for the insidious bacterium in aquaculture Piscirickettsia salmonis

    Article • Bioresource Technology, January 2017, Elsevier

    Joan Albiol

  22. Droplet digital PCR-aided screening and characterization ofPichia pastorismultiple gene copy strains

    Article • Biotechnology and Bioengineering, March 2016, Wiley

    Joan Albiol

  23. Integration and Validation of the Genome-Scale Metabolic Models of Pichia pastoris: A Comprehensive Update of Protein Glycosylation Pathways, Lipid and Energy Metabolism

    Article • PLOS One, January 2016, PLOS

    Joan Albiol

  24. Lactate and glucose concomitant consumption as a self-regulated pH detoxification mechanism in HEK293 cell cultures

    Article • Applied Microbiology and Biotechnology, August 2015, Springer Science + Business Media

    Joan Albiol

  25. Quantitative Metabolomics and Instationary 13C-Metabolic Flux Analysis Reveals Impact of Recombinant Protein Production on Trehalose and Energy Metabolism in Pichia pastoris

    Article • Metabolites, May 2014, MDPI AG

    Joan Albiol

  26. Metabolic flux analysis of recombinant Pichia pastoris growing on different glycerol/methanol mixtures by iterative fitting of NMR-derived 13C-labelling data from proteinogenic amino acids

    Article • New Biotechnology, January 2014, Elsevier

    Joan Albiol

  27. Use of chemostat cultures mimicking different phases of wine fermentations as a tool for quantitative physiological analysis

    Article • Microbial Cell Factories, January 2014, Springer Science + Business Media

    Joan Albiol

  28. 13C-Based Metabolic Flux Analysis in Yeast: The Pichia pastoris Case

    Article • January 2014, Springer Science + Business Media

    Joan Albiol

  29. 13C-Based Metabolic Flux Analysis of Recombinant Pichia pastoris

    Article • January 2014, Springer Science + Business Media

    Joan Albiol

  30. Metabolic Flux Analysis during the Exponential Growth Phase of Saccharomyces cerevisiae in Wine Fermentations

    Article • PLOS One, August 2013, PLOS

    Joan Albiol

  31. Glucose-methanol co-utilization in Pichia pastoris studied by metabolomics and instationary 13C flux analysis

    Article • BMC Systems Biology, February 2013, Springer Science + Business Media

    Joan Albiol

  32. Metabolic flux profiling of recombinant protein secreting Pichia pastoris growing on glucose:methanol mixtures

    Article • Microbial Cell Factories, May 2012, Springer Science + Business Media

    Joan Albiol

  33. Quantitative metabolomics analysis of amino acid metabolism in recombinant Pichia pastoris under different oxygen availability conditions

    Article • Microbial Cell Factories, January 2012, Springer Science + Business Media

    Joan Albiol

  34. Development of quantitative metabolomics for Pichia pastoris

    Article • Metabolomics, April 2011, Springer Science + Business Media

    Joan Albiol

  35. Areas of Research

    Article • January 2011, Springer Science + Business Media

    Joan Albiol, Natalie Leys

  36. A multi-level study of recombinant Pichia pastoris in different oxygen conditions

    Article • BMC Systems Biology, October 2010, Springer Science + Business Media

    Joan Albiol

  37. Macromolecular and elemental composition analysis and extracellular metabolite balances of Pichia pastoris growing at different oxygen levels

    Article • Microbial Cell Factories, December 2009, Springer Science + Business Media

    Joan Albiol

  38. Investigating the potential interactions between energy metabolism and recombinant protein production in Pichia pastoris by 13C-based metabolic flux analysis

    Article • New Biotechnology, September 2009, Elsevier

    Joan Albiol

  39. The Effect of Temperature on the Proteome of RecombinantPichia pastoris

    Article • Journal of Proteome Research, March 2009, American Chemical Society (ACS)

    Joan Albiol

  40. Static Mass Balance Studies of the MELiSSA Pilot Plant: Integration of a Higher Plant Chamber

    Article • July 2004, SAE International

    Joan Albiol

  41. Nitrification by immobilized cells in a micro-ecological life support system using packed-bed bioreactors: an engineering study

    Article • Journal of Chemical Technology & Biotechnology, June 2004, Wiley

    Joan Albiol

  42. The MELISSA pilot plant facility as an integration test-bed for advanced life support systems

    Article • Advances in Space Research, January 2004, Elsevier

    Joan Albiol

  43. MELISSA: a loop of interconnected bioreactors to develop life support in Space

    Article • Journal of Biotechnology, November 2002, Elsevier

    Joan Albiol

  44. Connection Between Different Compartments of the MELISSA Biological Life Support System

    Article • July 2001, SAE International

    Joan Albiol

  45. Scale-Up and Design of a Pilot-Plant Photobioreactor for the Continuous Culture of Spirulina platensis

    Article • Biotechnology Progress, June 2001, Wiley

    Joan Albiol

  46. Biological Life Support System Demostration Facility: The Melissa Pilot Plant

    Article • July 2000, SAE International

    Joan Albiol

  47. Modeling Photoheterotrophic Growth Kinetics of Rhodospirillum rubrum in Rectangular Photobioreactors

    Article • Biotechnology Progress, April 2000, Wiley

    Joan Albiol

  48. FEMME: a precursor experiment for the evaluation of bioregenerative life support systems

    Article • Planetary and Space Science, April 2000, Elsevier

    Joan Albiol

  49. Biomass Estimation in Plant Cell Cultures: A Neural Network Approach

    Article • Biotechnology Progress, January 1995, Wiley

    Joan Albiol

  50. Preliminary Studies on the Performance and Behaviour of the MELISSA Photoheterotrophic Compartment

    Article • June 1994, SAE International

    Joan Albiol

  51. Biomass Estimation in Plant Cell Cultures Using an Extended Kalman Filter

    Article • Biotechnology Progress, March 1993, Wiley

    Joan Albiol