All Stories

  1. Short-Term Vitamin B-6 Restriction Does Not Affect Plasma Concentrations of Hydrogen Sulfide Biomarkers Lanthionine and Homolanthionine in Healthy Men and Women

    Article • Journal of Nutrition, March 2016, American Society for Nutrition

    Dr Jesse F Gregory

  2. Pyridoxine supplementation does not alter in vivo kinetics of one-carbon metabolism but modifies patterns of one-carbon and tryptophan metabolites in vitamin B-6–insufficient oral contraceptive users

    Article • American Journal of Clinical Nutrition, July 2015, Oxford University Press (OUP)

    Dr Jesse F Gregory

  3. B6 biomarkers

    Article • Annual Review of Nutrition, July 2015, Annual Reviews

    Dr Jesse F Gregory, Professor Per Magne Ueland

  4. A directed-overflow and damage-control N -glycosidase in riboflavin biosynthesis

    Article • Biochemical Journal, February 2015, Portland Press Ltd.

    Dr Jesse F Gregory

  5. Metabolite Profile Analysis Reveals Association of Vitamin B-6 with Metabolites Related to One-Carbon Metabolism and Tryptophan Catabolism but Not with Biomarkers of Inflammation in Oral Contraceptive Users and Reveals the Effects of Oral Contraceptive...

    Article • Journal of Nutrition, November 2014, Oxford University Press (OUP)

    Dr Jesse F Gregory

  6. Folate is absorbed across the human colon: evidence by using enteric-coated caplets containing 13C-labeled [6S]-5-formyltetrahydrofolate

    Article • American Journal of Clinical Nutrition, September 2014, Oxford University Press (OUP)

    Dr Jesse F Gregory

  7. Vitamin B-6 Restriction Reduces the Production of Hydrogen Sulfide and its Biomarkers by the Transsulfuration Pathway in Cultured Human Hepatoma Cells1–3

    Article • Journal of Nutrition, August 2014, Oxford University Press (OUP)

    Dr Jesse F Gregory

  8. Divisions of labor in the thiamin biosynthetic pathway among organs of maize

    Article • Frontiers in Plant Science, August 2014, Frontiers

    Dr Jesse F Gregory

  9. Targeted metabolomics and mathematical modeling demonstrate that vitamin B-6 restriction alters one-carbon metabolism in cultured HepG2 cells

    Article • AJP Endocrinology and Metabolism, May 2014, American Physiological Society

    Dr Jesse F Gregory

  10. Pregnancy alters choline dynamics: results of a randomized trial using stable isotope methodology in pregnant and nonpregnant women

    Article • American Journal of Clinical Nutrition, October 2013, Oxford University Press (OUP)

    Dr Jesse F Gregory

  11. A cross-kingdom Nudix enzyme that pre-empts damage in thiamin metabolism

    Article • Biochemical Journal, September 2013, Portland Press Ltd.

    Dr Jesse F Gregory

  12. Metabolite Profile Analysis Reveals Functional Effects of 28-Day Vitamin B-6 Restriction on One-Carbon Metabolism and Tryptophan Catabolic Pathways in Healthy Men and Women1–3

    Article • Journal of Nutrition, August 2013, Oxford University Press (OUP)

    Dr Jesse F Gregory

  13. A Mathematical Model of Tryptophan Metabolism via the Kynurenine Pathway Provides Insights into the Effects of Vitamin B-6 Deficiency, Tryptophan Loading, and Induction of Tryptophan 2,3-Dioxygenase on Tryptophan Metabolites1–3

    Article • Journal of Nutrition, July 2013, Oxford University Press (OUP)

    Dr Jesse F Gregory

  14. Sarcosine and other metabolites along the choline oxidation pathway in relation to prostate cancer-A large nested case-control study within the JANUS cohort in Norway

    Article • International Journal of Cancer, July 2013, Wiley

    Dr Jesse F Gregory

  15. Metabolomic Analysis Reveals Extended Metabolic Consequences of Marginal Vitamin B-6 Deficiency in Healthy Human Subjects

    Article • PLoS ONE, June 2013, PLOS

    Dr Jesse F Gregory

  16. Vitamin B-6 restriction impairs fatty acid synthesis in cultured human hepatoma (HepG2) cells

    Article • AJP Endocrinology and Metabolism, December 2012, American Physiological Society

    Dr Jesse F Gregory

  17. Identification and Characterization of the Missing Pyrimidine Reductase in the Plant Riboflavin Biosynthesis Pathway

    Article • PLANT PHYSIOLOGY, November 2012, American Society of Plant Biologists (ASPB)

    Dr Jesse F Gregory

  18. Marginal Vitamin B-6 Deficiency Decreases Plasma (n-3) and (n-6) PUFA Concentrations in Healthy Men and Women1–3

    Article • Journal of Nutrition, September 2012, Oxford University Press (OUP)

    Dr Jesse F Gregory

  19. Vitamin B6

    Article • June 2012, Wiley

    Dr Jesse F Gregory

  20. Global hypothesis testing for high-dimensional repeated measures outcomes

    Article • Statistics in Medicine, December 2011, Wiley

    Dr Jesse F Gregory

  21. S-adenosyl-L-methionine Treatment for Alcoholic Liver Disease: A Double-Blinded, Randomized, Placebo-Controlled Trial

    Article • Alcoholism Clinical and Experimental Research, November 2011, Wiley

    Dr Jesse F Gregory, Dr John R. Richards

  22. Comparative genomics and functional analysis of the NiaP family uncover nicotinate transporters from bacteria, plants, and mammals

    Article • Functional & Integrative Genomics, September 2011, Springer Science + Business Media

    Dr Jesse F Gregory

  23. Effect of Pulsed Ultraviolet Light and High Hydrostatic Pressure on the Antigenicity of Almond Protein Extracts

    Article • Food and Bioprocess Technology, August 2011, Springer Science + Business Media

    Dr Jesse F Gregory

  24. Mathematical Modeling Predicts the Effect of Folate Deficiency and Excess on Cancer-Related Biomarkers

    Article • Cancer Epidemiology Biomarkers & Prevention, July 2011, American Association for Cancer Research (AACR)

    Dr Jesse F Gregory

  25. Folate Intake, Mthfr Genotype, and Sex Modulate Choline Metabolism in Mice1–3

    Article • Journal of Nutrition, June 2011, Oxford University Press (OUP)

    Dr Jesse F Gregory

  26. Folate Biosynthesis, Turnover, and Transport in Plants

    Article • Annual Review of Plant Biology, June 2011, Annual Reviews

    Dr Jesse F Gregory

  27. B-vitamin deficiency is protective against DSS-induced colitis in mice

    Article • AJP Gastrointestinal and Liver Physiology, May 2011, American Physiological Society

    Dr Jesse F Gregory

  28. Long-term effect of low-dose folic acid intake: potential effect of mandatory fortification on the prevention of neural tube defects

    Article • American Journal of Clinical Nutrition, May 2011, Oxford University Press (OUP)

    Dr Jesse F Gregory, Andrew Gray

  29. Biomarkers of vitamin B-12 status in NHANES: a roundtable summary1,5

    Article • American Journal of Clinical Nutrition, May 2011, Oxford University Press (OUP)

    Dr Jesse F Gregory

  30. Biomarkers of folate status in NHANES: a roundtable summary1,5

    Article • American Journal of Clinical Nutrition, May 2011, Oxford University Press (OUP)

    Dr Jesse F Gregory

  31. A 5-formyltetrahydrofolate cycloligase paralog from all domains of life: comparative genomic and experimental evidence for a cryptic role in thiamin metabolism

    Article • Functional & Integrative Genomics, May 2011, Springer Science + Business Media

    Dr Jesse F Gregory

  32. Moderate Vitamin B-6 Restriction Does Not Alter Postprandial Methionine Cycle Rates of Remethylation, Transmethylation, and Total Transsulfuration but Increases the Fractional Synthesis Rate of Cystathionine in Healthy Young Men and Women1–3

    Article • Journal of Nutrition, March 2011, Oxford University Press (OUP)

    Dr Jesse F Gregory

  33. MTHFR C677T genotype influences the isotopic enrichment of one-carbon metabolites in folate-compromised men consuming d9-choline

    Article • American Journal of Clinical Nutrition, December 2010, Oxford University Press (OUP)

    Dr Jesse F Gregory

  34. Moonlighting Glutamate Formiminotransferases Can Functionally Replace 5-Formyltetrahydrofolate Cycloligase

    Article • Journal of Biological Chemistry, October 2010, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Jesse F Gregory

  35. Functional analysis of folate polyglutamylation and its essential role in plant metabolism and development

    Article • The Plant Journal, September 2010, Wiley

    Dr Jesse F Gregory

  36. A central role for gamma-glutamyl hydrolases in plant folate homeostasis

    Article • The Plant Journal, September 2010, Wiley

    Dr Jesse F Gregory

  37. Impaired homocysteine transsulfuration is an indicator of alcoholic liver disease

    Article • Journal of Hepatology, September 2010, Elsevier

    Dr Jesse F Gregory, Dr John R. Richards

  38. A role for tetrahydrofolates in the metabolism of iron-sulfur clusters in all domains of life

    Article • Proceedings of the National Academy of Sciences, May 2010, Proceedings of the National Academy of Sciences

    Dr Jesse F Gregory

  39. Developmental and Feedforward Control of the Expression of Folate Biosynthesis Genes in Tomato Fruit

    Article • Molecular Plant, January 2010, Elsevier

    Dr Jesse F Gregory

  40. Identification of Transport-critical Residues in a Folate Transporter from the Folate-Biopterin Transporter (FBT) Family

    Article • Journal of Biological Chemistry, November 2009, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Jesse F Gregory

  41. FolX and FolM Are Essential for Tetrahydromonapterin Synthesis in Escherichia coli and Pseudomonas aeruginosa

    Article • Journal of Bacteriology, November 2009, ASM Journals

    Dr Jesse F Gregory

  42. Vitamin B-6 restriction tends to reduce the red blood cell glutathione synthesis rate without affecting red blood cell or plasma glutathione concentrations in healthy men and women

    Article • American Journal of Clinical Nutrition, June 2009, Oxford University Press (OUP)

    Dr Jesse F Gregory

  43. Folate is absorbed across the colon of adults: evidence from cecal infusion of 13C-labeled [6S]-5-formyltetrahydrofolic acid

    Article • American Journal of Clinical Nutrition, May 2009, Oxford University Press (OUP)

    Dr Jesse F Gregory

  44. Production of 1-Carbon Units from Glycine Is Extensive in Healthy Men and Women

    Article • Journal of Nutrition, February 2009, Oxford University Press (OUP)

    Dr Jesse F Gregory

  45. A Mathematical Model Gives Insights into the Effects of Vitamin B-6 Deficiency on 1-Carbon and Glutathione Metabolism1

    Article • Journal of Nutrition, February 2009, Oxford University Press (OUP)

    Dr Jesse F Gregory

  46. Moderate Dietary Vitamin B-6 Restriction Raises Plasma Glycine and Cystathionine Concentrations While Minimally Affecting the Rates of Glycine Turnover and Glycine Cleavage in Healthy Men and Women1

    Article • Journal of Nutrition, January 2009, Oxford University Press (OUP)

    Dr Jesse F Gregory

  47. Plant Vacuolar ATP-binding Cassette Transporters That Translocate Folates and Antifolates in Vitro and Contribute to Antifolate Tolerance in Vivo

    Article • Journal of Biological Chemistry, January 2009, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Jesse F Gregory

  48. DNA methylation determination by liquid chromatography-tandem mass spectrometry using novel biosynthetic [U-15N]deoxycytidine and [U-15N]methyldeoxycytidine internal standards

    Article • Nucleic Acids Research, September 2008, Oxford University Press (OUP)

    Dr Jesse F Gregory

  49. Tomato  -Glutamylhydrolases: Expression, Characterization, and Evidence for Heterodimer Formation

    Article • PLANT PHYSIOLOGY, August 2008, American Society of Plant Biologists (ASPB)

    Dr Jesse F Gregory

  50. Arabidopsis 10-Formyl Tetrahydrofolate Deformylases Are Essential for Photorespiration

    Article • The Plant Cell, July 2008, American Society of Plant Biologists (ASPB)

    Dr Jesse F Gregory

  51. Mathematical Modeling of Folate Metabolism: Predicted Effects of Genetic Polymorphisms on Mechanisms and Biomarkers Relevant to Carcinogenesis

    Article • Cancer Epidemiology Biomarkers & Prevention, July 2008, American Association for Cancer Research (AACR)

    Dr Jesse F Gregory

  52. Metabolism of the Folate Precursor p-Aminobenzoate in Plants: GLUCOSE ESTER FORMATION AND VACUOLAR STORAGE

    Article • Journal of Biological Chemistry, April 2008, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Jesse F Gregory

  53. DNA digestion to deoxyribonucleoside: A simplified one-step procedure

    Article • Analytical Biochemistry, February 2008, Elsevier

    Dr Jesse F Gregory

  54. Folate biofortification in food plants

    Article • Trends in Plant Science, January 2008, Elsevier

    Dr Jesse F Gregory

  55. Characterization of the folate salvage enzyme p-aminobenzoylglutamate hydrolase in plants

    Article • Phytochemistry, January 2008, Elsevier

    Dr Jesse F Gregory

  56. Improved methods for the preparation of [3H]folate polyglutamates: biosynthesis with Lactobacillus casei and enzymatic synthesis with Escherichia coli folylpolyglutamate synthetase

    Article • Analytical Biochemistry, December 2007, Elsevier

    Dr Jesse F Gregory

  57. Folate salvage in plants: pterin aldehyde reduction is mediated by multiple non-specific aldehyde reductases

    Article • The Plant Journal, June 2007, Wiley

    Dr Jesse F Gregory

  58. Folate biofortification of tomato fruit

    Article • Proceedings of the National Academy of Sciences, March 2007, Proceedings of the National Academy of Sciences

    Dr Jesse F Gregory

  59. Pterin and Folate Salvage. Plants and Escherichia coli Lack Capacity to Reduce Oxidized Pterins

    Article • PLANT PHYSIOLOGY, March 2007, American Society of Plant Biologists (ASPB)

    Dr Jesse F Gregory

  60. In silico experimentation with a model of hepatic mitochondrial folate metabolism

    Article • Theoretical Biology and Medical Modelling, December 2006, Springer Science + Business Media

    Dr Jesse F Gregory

  61. Evidence for folate‐salvage reactions in plants

    Article • The Plant Journal, March 2006, Wiley

    Dr Jesse F Gregory

  62. The analysis of folate and its metabolic precursors in biological samples

    Article • Analytical Biochemistry, January 2006, Elsevier

    Dr Jesse F Gregory

  63. Higher Plant Plastids and Cyanobacteria Have Folate Carriers Related to Those of Trypanosomatids

    Article • Journal of Biological Chemistry, September 2005, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Jesse F Gregory

  64. Plant  -Glutamyl Hydrolases and Folate Polyglutamates: CHARACTERIZATION, COMPARTMENTATION, AND CO-OCCURRENCE IN VACUOLES

    Article • Journal of Biological Chemistry, June 2005, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Jesse F Gregory

  65. Integrating the issues of folate bioavailability, intake and metabolism in the era of fortification

    Article • Trends in Food Science & Technology, June 2005, Elsevier

    Dr Jesse F Gregory

  66. 5-Formyltetrahydrofolate Is an Inhibitory but Well Tolerated Metabolite in Arabidopsis Leaves

    Article • Journal of Biological Chemistry, April 2005, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Jesse F Gregory

  67. Capillary Electrophoresis and High-Performance Liquid Chromatography Determination of Polyglutamyl 5-Methyltetrahydrofolate Forms in Citrus Products

    Article • Journal of Agricultural and Food Chemistry, March 2005, American Chemical Society (ACS)

    Dr Jesse F Gregory

  68. A Nudix Enzyme Removes Pyrophosphate from Dihydroneopterin Triphosphate in the Folate Synthesis Pathway of Bacteria and Plants

    Article • Journal of Biological Chemistry, December 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Jesse F Gregory

  69. Folate synthesis in plants: the last step of the p-aminobenzoate branch is catalyzed by a plastidial aminodeoxychorismate lyase

    Article • The Plant Journal, September 2004, Wiley

    Dr Jesse F Gregory

  70. Folate biofortification in tomatoes by engineering the pteridine branch of folate synthesis

    Article • Proceedings of the National Academy of Sciences, September 2004, Proceedings of the National Academy of Sciences

    Dr Jesse F Gregory

  71. Methylenetetrahydrofolate reductase 677C→T polymorphism affects DNA methylation in response to controlled folate intake in young women

    Article • The Journal of Nutritional Biochemistry, September 2004, Elsevier

    Dr Jesse F Gregory

  72. Folic Acid and the Prevention of Neural-Tube Defects

    Article • New England Journal of Medicine, May 2004, New England Journal of Medicine (NEJM/MMS)

    Dr Jesse F Gregory

  73. Partial amino acid sequence and mRNA analysis of cytosolic pyridoxine-beta-d-glucoside hydrolase from porcine intestinal mucosa: proposed derivation from the lactase-phlorizin hydrolase gene

    Article • Biochemical Journal, May 2004, Portland Press Ltd.

    Dr Jesse F Gregory

  74. Corrigenda for vol. 286, p. E272

    Article • AJP Endocrinology and Metabolism, April 2004, American Physiological Society

    Dr Jesse F Gregory

  75. Folate synthesis in plants: The p -aminobenzoate branch is initiated by a bifunctional PabA-PabB protein that is targeted to plastids

    Article • Proceedings of the National Academy of Sciences, January 2004, Proceedings of the National Academy of Sciences

    Dr Jesse F Gregory

  76. Single oral doses of C forms of pteroylmonoglutamic acid and 5-formyltetrahydrofolic acid elicit differences in short-term kinetics of labelled and unlabelled folates in plasma: potential problems in interpretation of folate bioavailability studies

    Article • British Journal Of Nutrition, August 2003, Cambridge University Press

    Dr Jesse F Gregory

  77. The Folate Precursor p -Aminobenzoate Is Reversibly Converted to Its Glucose Ester in the Plant Cytosol

    Article • Journal of Biological Chemistry, March 2003, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Jesse F Gregory

  78. Folate synthesis in plants: The first step of the pterin branch is mediated by a unique bimodular GTP cyclohydrolase I

    Article • Proceedings of the National Academy of Sciences, September 2002, Proceedings of the National Academy of Sciences

    Dr Jesse F Gregory

  79. INVIVOKINETICS OFFOLATEMETABOLISM

    Article • Annual Review of Nutrition, July 2002, Annual Reviews

    Dr Jesse F Gregory

  80. Synthesis and turnover of folates in plants

    Article • Current Opinion in Plant Biology, June 2002, Elsevier

    Dr Jesse F Gregory

  81. Enzymatic Hydrolysis of Pyridoxine-5'-beta -D-glucoside Is Catalyzed by Intestinal Lactase-Phlorizin Hydrolase

    Article • Journal of Biological Chemistry, May 2002, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Jesse F Gregory

  82. NUTRITIONAL PROPERTIES AND SIGNIFICANCE OF VITAMIN GLYCOSIDES

    Article • Annual Review of Nutrition, July 1998, Annual Reviews

    Dr Jesse F Gregory

  83. Cytosolic Pyridoxine- -D-Glucoside Hydrolase from Porcine Jejunal Mucosa: PURIFICATION, PROPERTIES, AND COMPARISON WITH BROAD SPECIFICITY  -GLUCOSIDASE

    Article • Journal of Biological Chemistry, December 1997, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Jesse F Gregory

  84. Preparation of stable isotopically labeled folates for in vivo investigation of folate absorption and metabolism

    Article • January 1997, Elsevier

    Dr Jesse F Gregory

  85. [7] Preparation of nonlabeled, tritiated, and deuterated pyridoxine 5′-β-d-glucoside and assay of pyridoxine-5′-β-d-glucoside hydrolase

    Article • January 1997, Elsevier

    Dr Jesse F Gregory

  86. The fate of [3H]folic acid in folate-adequate rats

    Article • The Journal of Nutritional Biochemistry, May 1996, Elsevier

    Dr Jesse F Gregory

  87. Modeling of Folate Metabolism1 1Presented in part at the conference entitled “Mathetmatical Modeling in Experimental Nutrition Conference V,” Fort Wayne, IN, May 8–11, 1994.

    Article • January 1996, Elsevier

    Dr Jesse F Gregory

  88. Relationship between urinary excretion of p-aminobenzoylglutamate and folate status of growing rats

    Article • Nutrition Research, June 1994, Elsevier

    Dr Jesse F Gregory

  89. Dietary vitamin B6 effects on the distribution of intestinal mucosal and microbial β-glucosidase activities toward pyridoxine-5′-β-?-glucoside in the guinea pig,

    Article • The Journal of Nutritional Biochemistry, May 1994, Elsevier

    Dr Jesse F Gregory

  90. Vitamin B6 in Raw/Fried Chicken

    Article • Journal of Food Science, September 1993, Wiley

    Dr Jesse F Gregory

  91. Intestinal β-glucosidase activity is not induced by chronic ingestion of pyridoxine-β-D-glucoside in rats

    Article • Nutrition Research, February 1991, Elsevier

    Dr Jesse F Gregory

  92. Adequacy of extraction techniques for determination of folate in foods and other biological materials

    Article • Journal of Food Composition and Analysis, June 1990, Elsevier

    Dr Jesse F Gregory

  93. Chemical and Nutritional Aspects of Folate Research: Analytical Procedures, Methods of Folate Synthesis, Stability, and Bioavailability of Dietary Folates

    Article • January 1989, Elsevier

    Dr Jesse F Gregory

  94. Chemical synthesis of deuterated folate monoglutamate and in vivo assessment of urinary excretion of deuterated folates in man

    Article • Analytical Biochemistry, April 1988, Elsevier

    Dr Jesse F Gregory

  95. Methods for determination of vitamin B6foods and other biological materials: A critical review

    Article • Journal of Food Composition and Analysis, March 1988, Elsevier

    Dr Jesse F Gregory

  96. Comparison of pteroylpolyglutamate hydrolase (folate conjugase) from porcine and human intestinal brush border membrane

    Article • Comparative Biochemistry and Physiology Part B Comparative Biochemistry, January 1987, Elsevier

    Dr Jesse F Gregory

  97. Degradation and Binding to Food Proteins of Vitamin B-6 Compounds During Thermal Processing

    Article • Journal of Food Science, September 1986, Wiley

    Dr Jesse F Gregory

  98. Determination of folypoly-γ-glutamate carboxypeptidase (folacin conjugase) activity using reversed-phase high-performance liquid chromatography

    Article • Journal of Chromatography A, January 1985, Elsevier

    Dr Jesse F Gregory

  99. Effect of dietary selenium on the metabolism of aflatoxin B1 in turkeys

    Article • Food and Chemical Toxicology, August 1984, Elsevier

    Dr Jesse F Gregory

  100. Metabolite distribution and rate of residue clearance in Turkeys fed a diet containing aflatoxin B1

    Article • Food and Chemical Toxicology, August 1983, Elsevier

    Dr Jesse F Gregory

  101. Determination of pyridoxal 5′-phosphate as the semicarbazone derivative using high-performance liquid chromatography

    Article • Analytical Biochemistry, March 1980, Elsevier

    Dr Jesse F Gregory