All Stories

  1. Placental and intra-amniotic inflammation are associated with altered fetal immune responses at birth

    Article • Placenta, September 2019, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  2. The Not-so-Sterile Womb: Evidence That the Human Fetus Is Exposed to Bacteria Prior to Birth

    Article • Frontiers in Microbiology, June 2019, Frontiers

    Professor, Head of Laboratories Jeffrey A Keelan

  3. Characterization of the bacterial microbiome in first‐pass meconium using propidium monoazide ( PMA ) to exclude nonviable bacterial DNA

    Article • Letters in Applied Microbiology, February 2019, Wiley

    Professor, Head of Laboratories Jeffrey A Keelan

  4. Re: “Amniotic fluid from healthy term pregnancies does not harbor a detectable microbial community” (2018) 6:87, https://doi.org/10.1186/s40168-018-0475-7

    Article • Microbiome, February 2019, Springer Science + Business Media

    Professor, Head of Laboratories Jeffrey A Keelan

  5. Profiling bacterial communities in low biomass samples: pitfalls and considerations

    Article • Microbiology Australia, January 2019, CSIRO Publishing

    Professor, Head of Laboratories Jeffrey A Keelan

  6. Murine exposure to gold nanoparticles during early pregnancy promotes abortion by inhibiting ectodermal differentiation

    Article • Extremophiles, December 2018, Springer Science + Business Media

    Professor, Head of Laboratories Jeffrey A Keelan

  7. Identification and removal of contaminating microbial DNA from PCR reagents: impact on low‐biomass microbiome analyses

    Article • Letters in Applied Microbiology, November 2018, Wiley

    Professor, Head of Laboratories Jeffrey A Keelan

  8. Intracellular speciation of gold nanorods alters the conformational dynamics of genomic DNA

    Article • Nature Nanotechnology, October 2018, Springer Science + Business Media

    Professor, Head of Laboratories Jeffrey A Keelan

  9. Relationship between umbilical cord sex hormone binding globulin, sex steroids, and age at menarche: a prospective cohort study

    Article • Fertility and Sterility, October 2018, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  10. The Relationship Between Pregnancy Exposure to Antidepressant and Atypical Antipsychotic Medications and Placental Weight and Birth Weight Ratio

    Article • Journal of Clinical Psychopharmacology, October 2018, Wolters Kluwer Health

    Professor, Head of Laboratories Jeffrey A Keelan

  11. Antenatal IL-1-dependent inflammation persists postnatally and causes retinal and sub-retinal vasculopathy in progeny

    Article • Scientific Reports, August 2018, Springer Science + Business Media

    Professor, Head of Laboratories Jeffrey A Keelan

  12. Toll-like Receptor-4: A New Target for Preterm Labour Pharmacotherapies?

    Article • Current Pharmaceutical Design, May 2018, Bentham Science Publishers

    Professor, Head of Laboratories Jeffrey A Keelan, Mark Hutchinson

  13. A Critical Review of the Bacterial Baptism Hypothesis and the Impact of Cesarean Delivery on the Infant Microbiome

    Article • Frontiers in Medicine, May 2018, Frontiers

    Professor, Head of Laboratories Jeffrey A Keelan

  14. The impact of antenatal Bisphenol A exposure on male reproductive function at 20–22 years of age

    Article • Reproductive BioMedicine Online, March 2018, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  15. Comparison of Meconium DNA Extraction Methods for Use in Microbiome Studies

    Article • Frontiers in Microbiology, February 2018, Frontiers

    Professor, Head of Laboratories Jeffrey A Keelan

  16. Intrauterine inflammatory activation, functional progesterone withdrawal, and the timing of term and preterm birth

    Article • Journal of Reproductive Immunology, February 2018, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  17. Maternal circulating adipokine profile and insulin resistance in women at high risk of developing gestational diabetes mellitus

    Article • Metabolism, October 2017, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  18. Recent advances in the prevention of preterm birth

    Article • F1000Research, July 2017, Faculty of 1000, Ltd.

    Professor, Head of Laboratories Jeffrey A Keelan

  19. Maternal-placental-fetal biodistribution of multimodal polymeric nanoparticles in a pregnant rat model in mid and late gestation

    Article • Scientific Reports, June 2017, Nature

    Professor, Head of Laboratories Jeffrey A Keelan

  20. Progesterone to prevent preterm birth: the studies are getting better, but there is still room for improvement

    Article • BJOG An International Journal of Obstetrics & Gynaecology, May 2017, Wiley

    Professor, Head of Laboratories Jeffrey A Keelan

  21. Reducing preterm birth by a statewide multifaceted program: an implementation study

    Article • American Journal of Obstetrics and Gynecology, May 2017, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  22. Cord blood androgen measurements: the importance of assay validation

    Article • Human Reproduction, April 2017, Oxford University Press (OUP)

    Professor, Head of Laboratories Jeffrey A Keelan

  23. Applying Precision Public Health to Prevent Preterm Birth

    Article • Frontiers in Public Health, April 2017, Frontiers

    Professor, Head of Laboratories Jeffrey A Keelan

  24. Umbilical cord androgens and estrogens in relation to verbal and nonverbal abilities at age 10 in the general population

    Article • PLoS ONE, March 2017, PLOS

    Professor, Head of Laboratories Jeffrey A Keelan

  25. Umbilical cord blood androgen levels and ASD-related phenotypes at 12 and 36 months in an enriched risk cohort study

    Article • Molecular Autism, January 2017, Springer Science + Business Media

    Professor, Head of Laboratories Jeffrey A Keelan

  26. The treatment of bacterial vaginosis in pregnancy with clindamycin to reduce the risk of infection-related preterm birth: a response to the Danish Society of Obstetrics and Gynecology guideline group's clinical recommendations

    Article • Acta Obstetricia Et Gynecologica Scandinavica, January 2017, Wiley

    Professor, Head of Laboratories Jeffrey A Keelan

  27. Planting the seed: Origins, composition, and postnatal health significance of the fetal gastrointestinal microbiota

    Article • Critical Reviews in Microbiology, December 2016, Taylor & Francis

    Professor, Head of Laboratories Jeffrey A Keelan

  28. IFPA meeting 2015 workshop report III: nanomedicine applications and exosome biology, xenobiotics and endocrine disruptors and pregnancy, and lipid

    Article • Placenta, December 2016, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  29. Preclinical evaluation of drugs to block inflammation-driven preterm birth

    Article • Innate Immunity, November 2016, SAGE Publications

    Professor, Head of Laboratories Jeffrey A Keelan

  30. Structural and morphologic differences in human oocytes after in vitro maturation compared with standard in vitro fertilization

    Article • Fertility and Sterility, November 2016, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  31. Ureaplasma parvum genotype, combined vaginal colonisation with Candida albicans, and spontaneous preterm birth in an Australian cohort of pregnant women

    Article • BMC Pregnancy and Childbirth, October 2016, Springer Science + Business Media

    Professor, Head of Laboratories Jeffrey A Keelan

  32. Early Life Events Predict Adult Testicular Function; Data Derived From the Western Australian (Raine) Birth Cohort

    Article • The Journal of Clinical Endocrinology & Metabolism, September 2016, Endocrine Society

    Professor, Head of Laboratories Jeffrey A Keelan

  33. Editorial: Advances in the Prevention and Treatment of Inflammation-Associated Preterm Birth

    Article • Frontiers in Immunology, June 2016, Frontiers

    Professor, Head of Laboratories Jeffrey A Keelan

  34. A global survey of clinical trials in pregnancy

    Article • BJOG An International Journal of Obstetrics & Gynaecology, June 2016, Wiley

    Professor, Head of Laboratories Jeffrey A Keelan

  35. A New, Potent, and Placenta-Permeable Macrolide Antibiotic, Solithromycin, for the Prevention and Treatment of Bacterial Infections in Pregnancy

    Article • Frontiers in Immunology, April 2016, Frontiers

    Professor, Head of Laboratories Jeffrey A Keelan

  36. T cell cytokine responses to stimulation with Ureaplasma parvum in pregnancy

    Article • Journal of Reproductive Immunology, March 2016, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  37. Role of Wnt signalling in early pregnancy

    Article • Reproduction Fertility and Development, January 2016, CSIRO Publishing

    Professor, Head of Laboratories Jeffrey A Keelan

  38. Changes in inflammatory mediators in gingival crevicular fluid following periodontal disease treatment in pregnancy: relationship to adverse pregnancy outcome

    Article • Journal of Reproductive Immunology, November 2015, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  39. Vaginal microbiota during pregnancy: Pathways of risk of preterm delivery in the absence of intrauterine infection?

    Article • Proceedings of the National Academy of Sciences, October 2015, Proceedings of the National Academy of Sciences

    Professor, Head of Laboratories Jeffrey A Keelan

  40. Testicular function in a birth cohort of young men

    Article • Human Reproduction, September 2015, Oxford University Press (OUP)

    Professor, Head of Laboratories Jeffrey A Keelan

  41. Prenatal testosterone exposure is related to sexually dimorphic facial morphology in adulthood

    Article • Proceedings of the Royal Society B Biological Sciences, September 2015, Royal Society Publishing

    Professor, Head of Laboratories Jeffrey A Keelan

  42. In vitro activity of solithromycin and its metabolites, CEM-214 and N-acetyl-CEM-101, against 100 clinical Ureaplasma spp. isolates compared with azithromycin

    Article • International Journal of Antimicrobial Agents, September 2015, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  43. Therapeutic and safety considerations of nanoparticle-mediated drug delivery in pregnancy

    Article • Nanomedicine, July 2015, Future Medicine

    Professor, Head of Laboratories Jeffrey A Keelan

  44. The perinatal androgen to estrogen ratio and autistic-like traits in the general population: a longitudinal pregnancy cohort study

    Article • Journal of Neurodevelopmental Disorders, June 2015, Springer Science + Business Media

    Professor, Head of Laboratories Jeffrey A Keelan

  45. In vitro maturation is associated with increased early embryo arrest without impairing morphokinetic development of useable embryos progressing to blastocysts

    Article • Human Reproduction, June 2015, Oxford University Press (OUP)

    Professor, Head of Laboratories Jeffrey A Keelan

  46. Whole blood flow cytometric analysis of Ureaplasma-stimulated monocytes from pregnant women

    Article • Journal of Reproductive Immunology, June 2015, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  47. Drugs to Block Cytokine Signaling for the Prevention and Treatment of Inflammation-Induced Preterm Birth

    Article • Frontiers in Immunology, April 2015, Frontiers

    Professor, Head of Laboratories Jeffrey A Keelan

  48. In This Issue

    Article • Journal of Developmental Origins of Health and Disease, April 2015, Cambridge University Press

    Professor, Head of Laboratories Jeffrey A Keelan

  49. Paracrine communication modulates production of Wnt antagonists and COX1-mediated prostaglandins in a decidual-trophoblast co-culture model

    Article • Molecular and Cellular Endocrinology, April 2015, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  50. Decreased STAT3 in human idiopathic fetal growth restriction contributes to trophoblast dysfunction

    Article • February 2015, Bioscientifica

    Professor, Head of Laboratories Jeffrey A Keelan

  51. Intra-amniotic pharmacological blockade of inflammatory signalling pathways in an ovine chorioamnionitis model

    Article • Molecular Human Reproduction, February 2015, Oxford University Press (OUP)

    Professor, Head of Laboratories Jeffrey A Keelan

  52. Effects of maternal n-3 fatty acid supplementation on placental cytokines, pro-resolving lipid mediators and their precursors

    Article • Reproduction, February 2015, Bioscientifica

    Professor, Head of Laboratories Jeffrey A Keelan, Professor Trevor A Mori

  53. Adult digit ratio (2D:4D) is not related to umbilical cord androgen or estrogen concentrations, their ratios or net bioactivity

    Article • Early Human Development, February 2015, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  54. Perinatal Testosterone Exposure and Cerebral Lateralisation in Adult Males: Evidence for the Callosal Hypothesis

    Article • Frontiers in Human Neuroscience, January 2015, Frontiers

    Professor, Head of Laboratories Jeffrey A Keelan

  55. Effects of omega-3 and omega-6 fatty acids on human placental cytokine production

    Article • Placenta, January 2015, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan, Professor Trevor A Mori

  56. The Maternal Serological Response to Intrauterine Ureaplasma sp. Infection and Prediction of Risk of Pre-Term Birth

    Article • Frontiers in Immunology, December 2014, Frontiers

    Professor, Head of Laboratories Jeffrey A Keelan

  57. Trans-placental passage and anti-inflammatory effects of solithromycin in the human placenta

    Article • Placenta, December 2014, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  58. Perinatal testosterone exposure and cerebral lateralisation in adult males: Evidence for the callosal hypothesis

    Article • Biological Psychology, December 2014, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  59. Letter to the editor: "Fatty acids and placental transport: insight or in vitro artifact?"

    Article • AJP Cell Physiology, December 2014, American Physiological Society

    Professor, Head of Laboratories Jeffrey A Keelan

  60. Strategies to Prevent Preterm Birth

    Article • Frontiers in Immunology, November 2014, Frontiers

    Professor, Head of Laboratories Jeffrey A Keelan

  61. Re-analysis of the association between perinatal androgens and pragmatic language ability

    Article • Psychoneuroendocrinology, November 2014, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  62. In vitro maturation as an alternative to standard in vitro fertilization for patients diagnosed with polycystic ovaries: a comparative analysis of fresh, frozen and cumulative cycle outcomes

    Article • Human Reproduction, October 2014, Oxford University Press (OUP)

    Professor, Head of Laboratories Jeffrey A Keelan

  63. Effects of nanoparticle size and gestational age on maternal biodistribution and toxicity of gold nanoparticles in pregnant mice

    Article • Toxicology Letters, October 2014, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  64. Maternal Intravenous Administration of Azithromycin Results in Significant Fetal Uptake in a Sheep Model of Second Trimester Pregnancy

    Article • Antimicrobial Agents and Chemotherapy, August 2014, ASM Journals

    Professor, Head of Laboratories Jeffrey A Keelan

  65. Re-analysis of the association between perinatal androgens and postnatal head circumference growth

    Article • Developmental Medicine & Child Neurology, August 2014, Wiley

    Professor, Head of Laboratories Jeffrey A Keelan

  66. Repeated maternal intramuscular or intraamniotic erythromycin incompletely resolves intrauterine Ureaplasma parvum infection in a sheep model of pregnancy

    Article • American Journal of Obstetrics and Gynecology, August 2014, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  67. Maternal Intravenous Treatment with either Azithromycin or Solithromycin Clears Ureaplasma parvum from the Amniotic Fluid in an Ovine Model of Intrauterine Infection

    Article • Antimicrobial Agents and Chemotherapy, June 2014, ASM Journals

    Professor, Head of Laboratories Jeffrey A Keelan

  68. Measurement of Androgen and Estrogen Concentrations in Cord Blood: Accuracy, Biological Interpretation, and Applications to Understanding Human Behavioral Development

    Article • Frontiers in Endocrinology, May 2014, Frontiers

    Professor, Head of Laboratories Jeffrey A Keelan

  69. The Relationship between Umbilical Cord Estrogens and Perinatal Characteristics

    Article • Cancer Epidemiology Biomarkers & Prevention, March 2014, American Association for Cancer Research (AACR)

    Professor, Head of Laboratories Jeffrey A Keelan

  70. Effects of cytokine-suppressive anti-inflammatory drugs on inflammatory activation in ex vivo human and ovine fetal membranes

    Article • January 2014, Bioscientifica

    Professor, Head of Laboratories Jeffrey A Keelan

  71. Second trimester amniotic fluid cytokine concentrations, Ureaplasma sp. colonisation status and sexual activity as predictors of preterm birth in Chinese and Australian women

    Article • BMC Pregnancy and Childbirth, January 2014, Springer Science + Business Media

    Professor, Head of Laboratories Jeffrey A Keelan

  72. High-Resolution Melt PCR Analysis for Genotyping of Ureaplasma parvum Isolates Directly from Clinical Samples

    Article • Journal of Clinical Microbiology, December 2013, ASM Journals

    Professor, Head of Laboratories Jeffrey A Keelan

  73. Polymyxin B Agonist Capture Therapy for Intrauterine Inflammation

    Article • Reproductive Sciences, November 2013, SAGE Publications

    Professor, Head of Laboratories Jeffrey A Keelan

  74. Maternal Administration of Solithromycin, a New, Potent, Broad-Spectrum Fluoroketolide Antibiotic, Achieves Fetal and Intra-Amniotic Antimicrobial Protection in a Pregnant Sheep Model

    Article • Antimicrobial Agents and Chemotherapy, November 2013, ASM Journals

    Professor, Head of Laboratories Jeffrey A Keelan

  75. The influence of antenatal exposure to phthalates on subsequent female reproductive development in adolescence: a pilot study

    Article • September 2013, Bioscientifica

    Professor, Head of Laboratories Jeffrey A Keelan

  76. The inflammatory state of the rat placenta increases in late gestation and is further enhanced by glucocorticoids in the labyrinth zone

    Article • Placenta, July 2013, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  77. Maternal dietary omega-3 fatty acid intake increases resolvin and protectin levels in the rat placenta

    Article • Journal of Lipid Research, May 2013, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor, Head of Laboratories Jeffrey A Keelan, Professor Trevor A Mori

  78. Placental ABC transporters, cellular toxicity and stress in pregnancy

    Article • Chemico-Biological Interactions, April 2013, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  79. Umbilical Cord Blood Testosterone and Childhood Internalizing and Externalizing Behavior: A Prospective Study

    Article • PLoS ONE, April 2013, PLOS

    Professor, Head of Laboratories Jeffrey A Keelan

  80. The association between perinatal testosterone concentration and early vocabulary development: A prospective cohort study

    Article • Biological Psychology, February 2013, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  81. The relationship between prenatal testosterone exposure and hemispheric asymmetry for language and spatial memory: A prospective cohort study

    Article • Frontiers in Human Neuroscience, January 2013, Frontiers

    Professor, Head of Laboratories Jeffrey A Keelan

  82. Maternal Dietary Omega-3 Fatty Acid Supplementation Reduces Placental Oxidative Stress and Increases Fetal and Placental Growth in the Rat

    Article • Biology of Reproduction, December 2012, Society for the Study of Reproduction

    Professor, Head of Laboratories Jeffrey A Keelan, Professor Trevor A Mori

  83. Effects of gestational age and surface modification on materno-fetal transfer of nanoparticles in murine pregnancy

    Article • Scientific Reports, November 2012, Nature

    Professor, Head of Laboratories Jeffrey A Keelan

  84. Perinatal testosterone exposure and autistic-like traits in the general population: a longitudinal pregnancy-cohort study

    Article • Journal of Neurodevelopmental Disorders, October 2012, Springer Science + Business Media

    Professor Craig Edward Pennell, Professor, Head of Laboratories Jeffrey A Keelan

  85. Ceramide biosynthesis and metabolism in trophoblast syncytialization

    Article • Molecular and Cellular Endocrinology, October 2012, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  86. Development of a Model for Functional Studies of ABCG2 (Breast Cancer Resistance Protein) Efflux Employing a Standard BeWo Clone (B24)

    Article • Assay and Drug Development Technologies, October 2012, Mary Ann Liebert Inc

    Professor, Head of Laboratories Jeffrey A Keelan

  87. Fetal Testosterone, Socio-Emotional Engagement and Language Development

    Article • Infant and Child Development, August 2012, Wiley

    Professor, Head of Laboratories Jeffrey A Keelan

  88. Androgen Concentrations in Umbilical Cord Blood and Their Association with Maternal, Fetal and Obstetric Factors

    Article • PLoS ONE, August 2012, PLOS

    Professor, Head of Laboratories Jeffrey A Keelan

  89. Sphingosine–sphingosine-1-phosphate pathway regulates trophoblast differentiation and syncytialization

    Article • Reproductive BioMedicine Online, February 2012, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  90. Sex-specific associations between umbilical cord blood testosterone levels and language delay in early childhood

    Article • Journal of Child Psychology and Psychiatry, January 2012, Wiley

    Professor, Head of Laboratories Jeffrey A Keelan

  91. Oxysterols exert proinflammatory effects in placental trophoblasts via TLR4-dependent, cholesterol-sensitive activation of NF- B

    Article • Molecular Human Reproduction, January 2012, Oxford University Press (OUP)

    Professor, Head of Laboratories Jeffrey A Keelan

  92. Inflammation of the Fetal Ovine Skin Following in utero Exposure to Ureaplasma parvum

    Article • Reproductive Sciences, October 2011, SAGE Publications

    Professor, Head of Laboratories Jeffrey A Keelan

  93. Homeobox gene Distal-less 3 (DLX3) is a regulator of villous cytotrophoblast differentiation

    Article • Placenta, October 2011, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  94. ABCA1 and placental cholesterol efflux

    Article • Placenta, September 2011, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  95. Maternal-amniotic-fetal distribution of macrolide antibiotics following intravenous, intramuscular, and intraamniotic administration in late pregnant sheep

    Article • American Journal of Obstetrics and Gynecology, June 2011, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  96. Nanoparticulate Drug Delivery in Pregnancy: Placental Passage and Fetal Exposure

    Article • Current Pharmaceutical Biotechnology, May 2011, Bentham Science Publishers

    Professor, Head of Laboratories Jeffrey A Keelan

  97. Nanotoxicology: Nanoparticles versus the placenta

    Article • Nature Nanotechnology, May 2011, Nature

    Professor, Head of Laboratories Jeffrey A Keelan

  98. Pharmacological inhibition of inflammatory pathways for the prevention of preterm birth

    Article • Journal of Reproductive Immunology, March 2011, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  99. Oxysterols inhibit differentiation and fusion of term primary trophoblasts by activating liver X receptors

    Article • Placenta, February 2011, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  100. Placental ABCA1 and ABCG1 transporters efflux cholesterol and protect trophoblasts from oxysterol induced toxicity

    Article • Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, September 2010, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  101. Regulation of trophoblast migration and survival by a novel neural regeneration peptide

    Article • Reproductive BioMedicine Online, August 2010, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  102. Pharmacological inhibition of inflammatory pathways for prevention of preterm birth

    Article • Journal of Reproductive Immunology, August 2010, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  103. Inhibition of choriodecidual cytokine production and inflammatory gene expression by selective I-κB kinase (IKK) inhibitors

    Article • Bone Marrow Transplantation, May 2010, Wiley

    Professor, Head of Laboratories Jeffrey A Keelan

  104. Innate inflammatory responses of human decidual cells to periodontopathic bacteria

    Article • American Journal of Obstetrics and Gynecology, May 2010, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  105. Antioxidant Defenses in the Rat Placenta in Late Gestation: Increased Labyrinthine Expression of Superoxide Dismutases, Glutathione Peroxidase 3, and Uncoupling Protein 2

    Article • Biology of Reproduction, April 2010, Society for the Study of Reproduction

    Professor, Head of Laboratories Jeffrey A Keelan

  106. IFPA Meeting 2009 Workshops Report

    Article • Placenta, March 2010, Elsevier

    Professor Rohan M Lewis, Professor, Head of Laboratories Jeffrey A Keelan

  107. Prevention of Inflammatory Activation of Human Gestational Membranes in an Ex Vivo Model Using a Pharmacological NF- B Inhibitor

    Article • The Journal of Immunology, September 2009, The American Association of Immunologists

    Professor, Head of Laboratories Jeffrey A Keelan

  108. Transport of lipids by ABC proteins: Interactions and implications for cellular toxicity, viability and function

    Article • Chemico-Biological Interactions, August 2009, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  109. Cannabinoids stimulate prostaglandin production by human gestational tissues through a tissue- and CB1-receptor-specific mechanism

    Article • AJP Endocrinology and Metabolism, December 2007, American Physiological Society

    Professor, Head of Laboratories Jeffrey A Keelan

  110. The ABC transporter BCRP/ABCG2 is a placental survival factor, and its expression is reduced in idiopathic human fetal growth restriction

    Article • The FASEB Journal, November 2007, Federation of American Societies For Experimental Biology (FASEB)

    Professor, Head of Laboratories Jeffrey A Keelan

  111. Expression, Localisation and Activity of ATP Binding Cassette (ABC) Family of Drug Transporters in Human Amnion Membranes

    Article • Placenta, August 2007, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  112. The Xenobiotic Transporter ABCG2 Plays a Novel Role in Differentiation of Trophoblast-like BeWo Cells

    Article • Placenta, April 2007, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  113. Placental Enzymes and Transporters: New Functions and Genetic Polymorphisms – A Workshop Report

    Article • Placenta, April 2007, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  114. Independent Regulation of Apical and Basolateral Drug Transporter Expression and Function in Placental Trophoblasts by Cytokines, Steroids, and Growth Factors

    Article • Drug Metabolism and Disposition, January 2007, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor, Head of Laboratories Jeffrey A Keelan

  115. Placental cytokines and preeclampsia

    Article • Frontiers in Bioscience, January 2007, Frontiers in Bioscience

    Professor, Head of Laboratories Jeffrey A Keelan

  116. Inflammation and normal labor

    Article • September 2006, Taylor & Francis

    Professor, Head of Laboratories Jeffrey A Keelan

  117. Active transport across the human placenta: impact on drug efficacy and toxicity

    Article • Expert Opinion on Drug Metabolism & Toxicology, February 2006, Informa Healthcare

    Professor, Head of Laboratories Jeffrey A Keelan

  118. Gestational Age-Dependent Up-Regulation of Prostaglandin D Synthase (PGDS) and Production of PGDS-Derived Antiinflammatory Prostaglandins in Human Placenta

    Article • The Journal of Clinical Endocrinology & Metabolism, February 2006, Endocrine Society

    Professor, Head of Laboratories Jeffrey A Keelan

  119. Expression of TGF-β1, TGF-β2, TGF-β3 and the Receptors TGF-βRI and TGF-βRII in Placentomes of Artificially Inseminated and Nuclear Transfer Derived Bovine Pregnancies

    Article • Placenta, February 2006, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  120. ABC drug transporter expression and functional activity in trophoblast-like cell lines and differentiating primary trophoblast

    Article • AJP Regulatory Integrative and Comparative Physiology, December 2005, American Physiological Society

    Professor, Head of Laboratories Jeffrey A Keelan

  121. Cytokines, Hypoxia, and Preeclampsia

    Article • Journal of the Society for Gynecologic Investigation, September 2005, SAGE Publications

    Professor, Head of Laboratories Jeffrey A Keelan

  122. Suppressors of cytokine signaling proteins in human preterm placental tissues

    Article • Journal of Molecular Endocrinology, August 2005, Bioscientifica

    Professor, Head of Laboratories Jeffrey A Keelan

  123. Nanomolar and Micromolar Effects of 15-Deoxy-Δ12,14-prostaglandin J2 on Amnion-Derived WISH Epithelial Cells: Differential Roles of Peroxisome Proliferator-Activated Receptors γ and δ and Nuclear Factor κB

    Article • Molecular Pharmacology, April 2005, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor, Head of Laboratories Jeffrey A Keelan

  124. Altered Placental Lactogen and Leptin Expression in Placentomes from Bovine Nuclear Transfer Pregnancies

    Article • Biology of Reproduction, August 2004, Society for the Study of Reproduction

    Professor, Head of Laboratories Jeffrey A Keelan

  125. Paradoxical Proinflammatory Actions of Interleukin-10 in Human Amnion: Potential Roles in Term and Preterm Labour

    Article • The Journal of Clinical Endocrinology & Metabolism, August 2004, Endocrine Society

    Professor, Head of Laboratories Jeffrey A Keelan

  126. HUMAN PLACENTAL GLUCURONIDATION AND TRANSPORT OF 3′AZIDO-3′-DEOXYTHYMIDINE AND URIDINE DIPHOSPHATE GLUCURONIC ACID

    Article • Drug Metabolism and Disposition, July 2004, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor, Head of Laboratories Jeffrey A Keelan

  127. Insulin resistance is not due to persistently elevated serum tumor necrosis-alpha levels in small for gestational age, premature, or twin children

    Article • Pediatric Diabetes, March 2004, Wiley

    Professor, Head of Laboratories Jeffrey A Keelan

  128. Insulin-Like Growth Factor-I and Binding Proteins 1, 2, and 3 in Bovine Nuclear Transfer Pregnancies

    Article • Biology of Reproduction, February 2004, Society for the Study of Reproduction

    Professor, Head of Laboratories Jeffrey A Keelan

  129. Drug Transfer and Metabolism by the Human Placenta

    Article • Clinical Pharmacokinetics, January 2004, Springer Science + Business Media

    Professor, Head of Laboratories Jeffrey A Keelan

  130. 3′-Azido-3′-deoxythymidine (AZT) induces apoptosis and alters metabolic enzyme activity in human placenta

    Article • Toxicology and Applied Pharmacology, October 2003, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  131. Epithelial Cell-Derived Neutrophil-Activating Peptide-78 Is Present in Fetal Membranes and Amniotic Fluid at Increased Concentrations with Intra-amniotic Infection and Preterm Delivery

    Article • Biology of Reproduction, September 2003, Society for the Study of Reproduction

    Professor, Head of Laboratories Jeffrey A Keelan

  132. Macrophage inhibitory cytokine 1 in fetal membranes and amniotic fluid from pregnancies with and without preterm labour and premature rupture of membranes

    Article • Molecular Human Reproduction, September 2003, Oxford University Press (OUP)

    Professor, Head of Laboratories Jeffrey A Keelan

  133. Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL), TRAIL Receptors, and the Soluble Receptor Osteoprotegerin in Human Gestational Membranes and Amniotic Fluid during Pregnancy and Labor at Term and Preterm

    Article • The Journal of Clinical Endocrinology & Metabolism, August 2003, Endocrine Society

    Professor, Head of Laboratories Jeffrey A Keelan

  134. Cytokines, Prostaglandins and Parturition—A Review

    Article • Placenta, April 2003, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  135. Maternal serum activin A is not elevated before preeclampsia in women who are at high risk

    Article • American Journal of Obstetrics and Gynecology, March 2003, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  136. Critical Paracrine Interactions Between TNF-  and IL-10 Regulate Lipopolysaccharide-Stimulated Human Choriodecidual Cytokine and Prostaglandin E2 Production

    Article • The Journal of Immunology, January 2003, The American Association of Immunologists

    Professor, Head of Laboratories Jeffrey A Keelan

  137. Metabolizing enzyme localization and activities in the first trimester human placenta: the effect of maternal and gestational age, smoking and alcohol consumption

    Article • Human Reproduction, October 2002, Oxford University Press (OUP)

    Professor, Head of Laboratories Jeffrey A Keelan

  138. Expression of angiogenic and neurotrophic factors in the human amnion and choriodecidua

    Article • American Journal of Obstetrics and Gynecology, September 2002, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  139. Expression of angiogenic and neurotrophic factors in the human amnion and choriodecidua

    Article • American Journal of Obstetrics and Gynecology, September 2002, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  140. Efficacy and specificity of non-steroidal anti-inflammatory drugs for the inhibition of cytokine-stimulated prostaglandin E2 secretion by amnion-derived WISH cells

    Article • Prostaglandins Leukotrienes and Essential Fatty Acids, May 2002, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  141. Use of cDNA arrays to generate differential expression profiles for inflammatory genes in human gestational membranes delivered at term and preterm

    Article • Molecular Human Reproduction, April 2002, Oxford University Press (OUP)

    Professor, Head of Laboratories Jeffrey A Keelan

  142. Cytokines of the Placenta and Extra-placental Membranes: Roles and Regulation During Human Pregnancy and Parturition

    Article • Placenta, April 2002, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  143. Cytokines of the Placenta and Extra-placental Membranes: Biosynthesis, Secretion and Roles in Establishment of Pregnancy in Women

    Article • Placenta, April 2002, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  144. Identification of Suppressors of Cytokine Signaling (SOCS) Proteins in Human Gestational Tissues: Differential Regulation Is Associated with the Onset of Labor

    Article • The Journal of Clinical Endocrinology & Metabolism, March 2002, Endocrine Society

    Professor, Head of Laboratories Jeffrey A Keelan

  145. Identification of Suppressors of Cytokine Signaling (SOCS) Proteins in Human Gestational Tissues: Differential Regulation Is Associated with the Onset of Labor

    Article • The Journal of Clinical Endocrinology & Metabolism, March 2002, Endocrine Society

    Professor, Head of Laboratories Jeffrey A Keelan

  146. UDP-glucuronosyltransferase activity, expression and cellular localization in human placenta at term

    Article • Biochemical Pharmacology, February 2002, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  147. Serum Activin A, Inhibin A, and Follistatin Concentrations in Preeclampsia or Small for Gestational Age Pregnancies

    Article • Obstetrics and Gynecology, February 2002, Wolters Kluwer Health

    Professor, Head of Laboratories Jeffrey A Keelan

  148. Serum activin A, inhibin A, and follistatin concentrations in preeclampsia or small for gestational age pregnancies

    Article • Obstetrics and Gynecology, February 2002, Wolters Kluwer Health

    Professor, Head of Laboratories Jeffrey A Keelan

  149. Regulation of prostaglandin production in an immortalized human myometrial cell line by cytokines and non-steroidal anti-inflammatory drugs

    Article • European Journal of Obstetrics & Gynecology and Reproductive Biology, January 2002, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  150. 15-deoxy-Δ12,14-prostaglandin J2-induced apoptosis in amnion-like WISH cells

    Article • Prostaglandins & Other Lipid Mediators, December 2001, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  151. Expression of Interleukin-1β mRNA in Murine Uterine and Gestational Tissues: Relationship with Gestational Age1

    Article • American Journal of Reproductive Immunology, December 2001, Wiley

    Professor, Head of Laboratories Jeffrey A Keelan

  152. Expression of prostaglandin H synthase-1 and -2 in murine intrauterine and gestational tissues from mid pregnancy until term

    Article • Prostaglandins & Other Lipid Mediators, August 2001, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  153. Hypoxia Attenuates PGE2but Increases Prostacyclin and Thromboxane Production in Human Term Villous Trophoblast

    Article • Placenta, July 2001, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  154. Predicting preterm delivery: comparison of cervicovaginal interleukin (IL)-1β, IL-6 and IL-8 with fetal fibronectin and cervical dilatation

    Article • European Journal of Obstetrics & Gynecology and Reproductive Biology, April 2001, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  155. Cytosolic phospholipase A2and 15-hydroxyprostaglandin dehydrogenase mRNA expression in murine uterine and gestational tissues during late pregnancy

    Article • Prostaglandins Leukotrienes and Essential Fatty Acids, April 2001, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  156. Gestational age-dependent effects of lipopolysaccharide on prostaglandin production by murine decidual caps

    Article • Prostaglandins Leukotrienes and Essential Fatty Acids, February 2001, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  157. Regulation of activin a, inhibin a, and follistatin production in human amnion and choriodecidual explants by inflammatory mediators

    Article • Journal of the Society for Gynecologic Investigation, October 2000, SAGE Publications

    Professor, Head of Laboratories Jeffrey A Keelan

  158. Corticotropin-releasing hormone, corticotropin-releasing hormone–binding protein, and activin A in maternal serum: Prediction of preterm delivery and response to glucocorticoids in women with symptoms of preterm labor

    Article • American Journal of Obstetrics and Gynecology, September 2000, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  159. Intercellular Adhesion Molecule-1 (ICAM-1) in Cervicovaginal Fluid of Women Presenting with Preterm Labor: Predictive Value for Preterm Delivery

    Article • American Journal of Reproductive Immunology, May 2000, Wiley

    Professor, Head of Laboratories Jeffrey A Keelan

  160. The 15-Deoxy-Δ12,14-prostaglandin J2Receptor, Peroxisome Proliferator Activated Receptor-γ (PPARγ) is Expressed in Human Gestational Tissues and is Functionally Active in JEG3 Choriocarcinoma Cells

    Article • Placenta, May 2000, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  161. Does Leptin Exhibit Cytokine-Like Properties in Tissues of Pregnancy?

    Article • American Journal of Reproductive Immunology, May 2000, Wiley

    Professor, Head of Laboratories Jeffrey A Keelan

  162. Prostanoid stimulation of cytokine production in an amnion-derived cell line: evidence of a feed-forward mechanism with implications for term and preterm labor

    Article • Journal of the Society for Gynecologic Investigation, February 2000, SAGE Publications

    Professor, Head of Laboratories Jeffrey A Keelan

  163. Enhanced Expression of Intercellular Adhesion Molecule-1 (ICAM-1) in Amnion with Term and Preterm Labour

    Article • Placenta, January 2000, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  164. Cytokine-induced coordinate expression of enzymes of prostaglandin biosynthesis and metabolism: 15-hydroxyprostaglandin dehydrogenase

    Article • Prostaglandins Leukotrienes and Essential Fatty Acids, January 2000, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  165. Activin A Exerts both Pro- and Anti-inflammatory Effects on Human Term Gestational Tissues

    Article • Placenta, January 2000, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  166. Cytokine abundance in placental tissues: Evidence of inflammatory activation in gestational membranes with term and preterm parturition

    Article • American Journal of Obstetrics and Gynecology, December 1999, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  167. Characterization of the amnion-derived AV3 cell line for use as a model for investigation of prostaglandin-cytokine interactions in human amnion

    Article • Prostaglandins Leukotrienes and Essential Fatty Acids, December 1999, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  168. Concentrations of activin A, inhibin A and follistatin in human amnion, choriodecidual and placental tissues at term and preterm

    Article • Journal of Endocrinology, October 1999, Bioscientifica

    Professor, Head of Laboratories Jeffrey A Keelan

  169. 15-Deoxy-Δ12,14-prostaglandin J2, a Ligand for Peroxisome Proliferator-Activated Receptor-γ, Induces Apoptosis in JEG3 Choriocarcinoma Cells

    Article • Biochemical and Biophysical Research Communications, September 1999, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  170. Key enzymes of prostaglandin biosynthesis and metabolism. Coordinate regulation of expression by cytokines in gestational tissues: a review

    Article • Prostaglandins & Other Lipid Mediators, June 1999, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  171. Regulation of Cytosolic Phospholipase A2 Expression by Cytokines in Human Amnion Cells

    Article • Placenta, May 1999, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  172. Interleukin-4 differentially regulates prostaglandin production in amnion-derived WISH cells stimulated with pro-inflammatory cytokines and epidermal growth factor

    Article • Prostaglandins Leukotrienes and Essential Fatty Acids, April 1999, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  173. Expression of intercellular adhesion molecule-1 (ICAM-1) in choriodecidua with labour and delivery at term and preterm

    Article • Reproduction Fertility and Development, January 1999, CSIRO Publishing

    Professor, Head of Laboratories Jeffrey A Keelan

  174. Labor-Associated Changes in Interleukin-10 Production and Its Regulation by Immunomodulators in Human Choriodecidua

    Article • The Journal of Clinical Endocrinology & Metabolism, December 1998, Endocrine Society

    Professor, Head of Laboratories Jeffrey A Keelan

  175. Effects of interleukin-4 on the expression and activity of prostaglandin endoperoxide H synthase-2 in amnion-derived WISH cells

    Article • Journal of Molecular Endocrinology, December 1998, Bioscientifica

    Professor, Head of Laboratories Jeffrey A Keelan

  176. Comparative Studies on the Effects of Interleukin-4 and Interleukin-13 on Cytokine and Prostaglandin E2 Production by Amnion-derived WISH Cells

    Article • American Journal of Reproductive Immunology, November 1998, Wiley

    Professor, Head of Laboratories Jeffrey A Keelan

  177. Regulation of activin-A production by human amnion, decidua and placenta in vitro by pro-inflammatory cytokines

    Article • Placenta, July 1998, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  178. The Effects of a Ceramide Analogue, N-acetylsphingosine, on Basal and Tumor Necrosis Factor-α-Stimulated Production of Prostaglandins and Cytokines in Gestational Tissues

    Article • Prostaglandins & Other Lipid Mediators, February 1998, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  179. Interleukin (IL)-6 and IL-8 production by human amnion: regulation by cytokines, growth factors, glucocorticoids, phorbol esters, and bacterial lipopolysaccharide

    Article • Biology of Reproduction, December 1997, Society for the Study of Reproduction

    Professor, Head of Laboratories Jeffrey A Keelan

  180. Regulation of Interleukin (IL)-6 and IL-8 Production in an Amnion-derived Cell Line by Cytokines, Growth Factors, Glucocorticoids, and Phorbol Esters

    Article • American Journal of Reproductive Immunology, October 1997, Wiley

    Professor, Head of Laboratories Jeffrey A Keelan

  181. Prostaglandin H synthase-2 and cytosolic phospholipase A2 in the hypoxic-ischemic brain: role in neuronal death or survival?

    Article • Molecular Brain Research, October 1997, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  182. The Molecular Mechanisms of Term and Preterm Labor: Recent Progress and Clinical Implications

    Article • Clinical Obstetrics & Gynecology, September 1997, Wolters Kluwer Health

    Professor, Head of Laboratories Jeffrey A Keelan

  183. Serum Concentrations of Human Chorionic Gonadotrophs and Immunoreactive Inhibin in Early Pregnancy and Recurrent Miscarriage: A Longitudinal Study

    Article • Australian and New Zealand Journal of Obstetrics and Gynaecology, August 1996, Wiley

    Professor, Head of Laboratories Jeffrey A Keelan

  184. Activin-A stimulates, while transforming growth factor β1 inhibits,chorionic gonadotrophin production and aromatase activity in cultured human placental trophoblasts

    Article • Placenta, January 1996, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  185. Comparative regulation of inhibin, activin and human chorionic gonadotropin production by placental trophoblast cells in culture

    Article • Placenta, December 1994, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan

  186. Sex Differences in Umbilical Cord Serum Levels of Inhibin, Testosterone, Oestradiol Dehydroepiandrosterone Sulphate, and Sex Hormone-Binding Globulin in Human Term Neonates

    Article • Neonatology, January 1994, Karger Publishers

    Professor, Head of Laboratories Jeffrey A Keelan

  187. A radioimmunoassay for plasma dehydroepiandrosterone sulphate incorporating placental steroid sulphatase as a hydrolysing reagent

    Article • Journal of Steroid Biochemistry, September 1986, Elsevier

    Professor, Head of Laboratories Jeffrey A Keelan