All Stories

  1. Blocking late stages of splicing quickly limits pre-spliceosome assembly in vivo

    Article • RNA Biology, September 2019, Taylor & Francis

    Professor Jean D Beggs

  2. Mutagenesis of Snu114 domain IV identifies a developmental role in meiotic splicing

    Article • RNA Biology, January 2019, Taylor & Francis

    Professor Jean D Beggs

  3. Noreen Elizabeth Murray CBE. 26 February 1935 -- 12 May 2011

    Article • Biographical Memoirs of Fellows of the Royal Society, July 2014, Royal Society Publishing

    Professor Jean D Beggs

  4. A Splicing-Dependent Transcriptional Checkpoint Associated with Prespliceosome Formation

    Article • Molecular Cell, March 2014, Elsevier

    Professor Jean D Beggs

  5. RNA helicases in splicing

    Article • RNA Biology, January 2013, Taylor & Francis

    Professor Jean D Beggs

  6. Structure, function and regulation of spliceosomal RNA helicases

    Article • Current Opinion in Cell Biology, June 2012, Elsevier

    Professor Jean D Beggs

  7. Yeast Genetics to Investigate the Function of Core Pre-mRNA Splicing Factors

    Article • February 2012, Wiley

    Professor Jean D Beggs

  8. Modelling Reveals Kinetic Advantages of Co-Transcriptional Splicing

    Article • PLoS Computational Biology, October 2011, PLOS

    Professor Jean D Beggs

  9. Splicing-Dependent RNA Polymerase Pausing in Yeast

    Article • Molecular Cell, November 2010, Elsevier

    Professor Jean D Beggs

  10. Cross-talk in transcription, splicing and chromatin: who makes the first call?

    Article • Biochemical Society Transactions, October 2010, Portland Press Ltd.

    Professor Jean D Beggs

  11. Brr2p RNA helicase with a split personality: insights into structure and function: Figure 1

    Article • Biochemical Society Transactions, August 2010, Portland Press Ltd.

    Professor Jean D Beggs

  12. Prognosis for splicing factor PRPF8 retinitis pigmentosa, novel mutations and correlation between human and yeast phenotypes

    Article • Human Mutation, March 2010, Wiley

    Professor Jean D Beggs

  13. Processivity and Coupling in Messenger RNA Transcription

    Article • PLoS ONE, January 2010, PLOS

    Professor Jean D Beggs

  14. Interaction of yeast eIF4G with spliceosome components: Implications in pre-mRNA processing events

    Article • RNA Biology, November 2009, Taylor & Francis

    Professor Jean D Beggs

  15. Analysis of Lsm1p and Lsm8p domains in the cellular localization of Lsm complexes in budding yeast

    Article • FEBS Journal, June 2009, Wiley

    Professor Jean D Beggs

  16. Spliceosomal Machinery

    Article • December 2007, Wiley

    Professor Jean D Beggs

  17. prp8 mutations that cause human retinitis pigmentosa lead to a U5 snRNP maturation defect in yeast

    Article • Nature Structural & Molecular Biology, October 2007, Springer Science + Business Media

    Professor Jean D Beggs

  18. Investigation of mRNA Splicing in Saccharomyces cerevisiae using Microarrays

    Article • BMC Bioinformatics, September 2005, Springer Science + Business Media

    Professor Jean D Beggs

  19. Crosstalk between RNA metabolic pathways: an RNOMICS approach

    Article • Nature Reviews Molecular Cell Biology, May 2005, Springer Science + Business Media

    Professor Jean D Beggs

  20. Lsm Proteins Promote Regeneration of Pre-mRNA Splicing Activity

    Article • Current Biology, August 2004, Elsevier

    Professor Jean D Beggs

  21. Splicing goes global

    Article • Trends in Genetics, June 2003, Elsevier

    Professor Jean D Beggs

  22. Vac14 Controls PtdIns(3,5) P 2 Synthesis and Fab1-Dependent Protein Trafficking to the Multivesicular Body

    Article • Current Biology, June 2002, Elsevier

    Professor Jean D Beggs, Dr David C Hughes

  23. Spliceosomal Machinery

    Article • April 2001, Wiley

    Professor Jean D Beggs

  24. Functional analyses of interacting factors involved in both pre-mRNA splicing and cell cycle progression in Saccharomyces cerevisiae

    Article • RNA, November 2000, Cold Spring Harbor Laboratory Press

    Professor Jean D Beggs

  25. Yeast Sm-like proteins function in mRNA decapping and decay

    Article • Nature, March 2000, Springer Science + Business Media

    Professor Jean D Beggs

  26. Genome-Wide Protein Interaction Screens Reveal Functional Networks Involving Sm-Like Proteins

    Article • Yeast, January 2000, Hindawi Publishing Corporation

    Professor Jean D Beggs

  27. Characterization of U6 snRNA–protein interactions

    Article • RNA, November 1999, Cold Spring Harbor Laboratory Press

    Professor Jean D Beggs

  28. The identification and characterization of a novel splicing protein, Isy1p, of Saccharomyces cerevisiae

    Article • RNA, March 1999, Cold Spring Harbor Laboratory Press

    Professor Jean D Beggs

  29. Protein-RNA interactions in the U5 snRNP of Saccharomyces cerevisiae

    Article • RNA, December 1998, Cold Spring Harbor Laboratory Press

    Professor Jean D Beggs

  30. Protein–RNA interactions in the U5 snRNP of Saccharomyces cerevisiae

    Article • RNA, October 1998, Cold Spring Harbor Laboratory Press

    Professor Jean D Beggs

  31. Identification and functional analysis of hPRP17, the human homologue of the PRP17/CDC40 yeast gene involved in splicing and cell cycle control

    Article • RNA, October 1998, Cold Spring Harbor Laboratory Press

    Professor Jean D Beggs

  32. Extraordinary sequence conservation of the PRP8 splicing factor

    Article • Yeast, April 1995, Wiley

    Professor Jean D Beggs

  33. Interaction of the yeast splicing factor PRP8 with substrate RNA during both steps of splicing

    Article • Nucleic Acids Research, January 1995, Oxford University Press (OUP)

    Professor Jean D Beggs

  34. Cloning and characterisation of the gene encoding the ribosomal protien S5 (also known as rp14, S2, YS8) of Saccharomyces cerevisiae

    Article • Nucleic Acids Research, January 1995, Oxford University Press (OUP)

    Professor Jean D Beggs

  35. RNA Splicing: U2 fulfils a commitment

    Article • Current Biology, March 1994, Elsevier

    Professor Jean D Beggs

  36. Yeast protein splicing factors involved in nuclear pre-mRNA splicing

    Article • Molecular Biology Reports, August 1993, Springer Science + Business Media

    Professor Jean D Beggs

  37. Detection of a plant protein analogous to the yeast spliceosomal protein, PRP8

    Article • FEBS Letters, February 1993, Wiley

    Professor Jean D Beggs

  38. Branched poly-labelled oligonucleotides: enhanced specificity of fork-shaped biotinylated oligoribonucleotides for antisense affinity selection

    Article • Nucleic Acids Research, January 1993, Oxford University Press (OUP)

    Professor Jean D Beggs

  39. The genetics of nuclear pre-mRNA splicing: a complex story

    Article • Antonie van Leeuwenhoek, August 1992, Springer Science + Business Media

    Professor Jean D Beggs

  40. The genetics of nuclear pre-mRNA splicing: a complex story

    Article • January 1992, Springer Science + Business Media

    Professor Jean D Beggs

  41. Production of cytochrome P450 reductase yeast-rat hybrid proteins in Saccharomyces cerevisiae

    Article • Gene, January 1992, Elsevier

    Professor Jean D Beggs, Dr H Frances J BLIGH

  42. A suppressor of a yeast splicing mutation (prp8-l) encodes a putative ATP-dependent RNA helicase

    Article • Nature, February 1991, Springer Science + Business Media

    Professor Jean D Beggs

  43. The yeast PRP8 protein intersacts directly with pre-mRNA

    Article • Nucleic Acids Research, January 1991, Oxford University Press (OUP)

    Professor Jean D Beggs

  44. Polypeptide components of Drosophila small nuclear ribonucleoprotein particles

    Article • Nucleic Acids Research, January 1991, Oxford University Press (OUP)

    Professor Jean D Beggs

  45. Evolutionary conservation of the spliceosaomal protein, U2 B”

    Article • Nucleic Acids Research, January 1991, Oxford University Press (OUP)

    Professor Jean D Beggs

  46. Interactions of PRP2 protein with pre-mRNA splicing complexes in Saccharomyces cerevisiae

    Article • Nucleic Acids Research, January 1990, Oxford University Press (OUP)

    Professor Jean D Beggs

  47. Protein interactions in nuclear pre-mRNA splicing in Saccharomyces cerevisiae

    Article • Molecular Biology Reports, January 1990, Springer Science + Business Media

    Professor Jean D Beggs

  48. Conservation between yeast and man of a protein associated with U5 small nuclear ribonucleoprotein

    Article • Nature, December 1989, Springer Science + Business Media

    Professor Jean D Beggs

  49. The product of the PRP4 gene of S. cerevisiae shows homology to β subunits of G proteins

    Article • Cell, September 1989, Elsevier

    Professor Jean D Beggs

  50. The expression of cytochrome P450IIB1 in Saccharomyces cerevisia results in an increased mutation frequency when exposed to cyclophosphamide

    Article • Carcinogenesis, January 1989, Oxford University Press (OUP)

    Professor Jean D Beggs

  51. Identification of a yeast snRNP protein and detection of snRNP-snRNP interactions

    Article • Cell, December 1987, Elsevier

    Professor Jean D Beggs

  52. Identification of theRNA2 protein ofSaccharomyces cerevisiae

    Article • Yeast, March 1986, Wiley

    Professor Jean D Beggs

  53. Abnormal expression of chromosomal rabbit β-globin gene in Saccharomyces cerevisiae

    Article • Nature, February 1980, Springer Science + Business Media

    Professor Jean D Beggs

  54. SYNTHESIS OF RABBIT β-GLOBIN-SPECIFIC RNA IN MOUSE L CELLS AND YEAST TRANSFORMED WITH CLONED RABBIT CHROMOSOMAL β-GLOBIN DNA

    Article • January 1979, Elsevier

    Professor Jean D Beggs

  55. High efficiency yeast transformation

    Article • Nature, September 1978, Springer Science + Business Media

    Professor Jean D Beggs

  56. The construction in vitro of transducing derivatives of phage lambda

    Article • January 1976

    Professor Jean D Beggs

  57. A map of the restriction targets in yeast 2 micron plasmid DNA cloned on bacteriophage lambda

    Article • January 1976

    Professor Jean D Beggs