All Stories

  1. Systematic modeling-driven experiments identify distinct molecular clockworks underlying hierarchically organized pacemaker neurons
  2. Universally valid reduction of multiscale stochastic biochemical systems using simple non-elementary propensities
  3. Misuse of the Michaelis–Menten rate law for protein interaction networks and its remedy
  4. Model-driven experimental approach reveals the complex regulatory distribution of p53 by the circadian factor Period 2
  5. Review for two types of mathematical models of molecular circadian clocks
  6. Can we use Hill-type functions for stochastic simulations?
  7. A Period2 Phosphoswitch Regulates and Temperature Compensates Circadian Period
  8. Emergent genetic oscillations in a synthetic microbial consortium
  9. The Validity of Quasi-Steady-State Approximations in Discrete Stochastic Simulations
  10. Molecular Mechanisms that Regulate the Coupled Period of the Mammalian Circadian Clock
  11. A Novel Protein, CHRONO, Functions as a Core Component of the Mammalian Circadian Clock
  12. Modeling and Validating Chronic Pharmacological Manipulation of Circadian Rhythms
  13. Mechanisms That Enhance Sustainability of p53 Pulses
  14. A mechanism for robust circadian timekeeping via stoichiometric balance
  15. On the Existence and Uniqueness of Biological Clock Models Matching Experimental Data