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  1. Quantitative cytokine level of TNF-α, IFN-γ, IL-10, TGF-β and circulating Epstein-Barr virus DNA load in individuals with acute Malaria due to P. falciparum or P. vivax or double infection in a Malaria endemic region in Indonesia

    Article • PLoS ONE, December 2021, PLOS

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  2. Cumulative Roles for Epstein-Barr Virus, Human Endogenous Retroviruses, and Human Herpes Virus-6 in Driving an Inflammatory Cascade Underlying MS Pathogenesis

    Article • Frontiers in Immunology, November 2021, Frontiers

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  3. Epstein-Barr DNA in advanced pediatric nasopharyngeal cancer

    Article • Paediatrica Indonesiana, September 2021, Paediatrica Indonesiana - Indonesian Pediatric Society

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  4. PCR-Free Shallow Whole Genome Sequencing for Chromosomal Copy Number Detection from Plasma of Cancer Patients Is an Efficient Alternative to the Conventional PCR-Based Approach

    Article • Journal of Molecular Diagnostics, August 2021, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  5. Rapid nasopharyngeal brush-smear cytology with Epstein-Barr virus DNA load and viral marker analysis for detection of nasopharyngeal carcinoma

    Article • Otorhinolaryngology-Head and Neck Surgery, January 2021, Open Access Text Pvt, Ltd.

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  6. Cytolytic Epstein-Barr Virus Reactivation Therapy for EBV-Associated Gastric Carcinoma

    Article • Clinical Oncology and Research, July 2020, Science Repository OU

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  7. Correction: Identification of a Novel, EBV-based Antibody Risk Stratification Signature for Early Detection of Nasopharyngeal Carcinoma in Taiwan

    Article • Clinical Cancer Research, July 2020, American Association for Cancer Research (AACR)

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  8. Epidemiology of Epstein-Barr virus infection and infectious mononucleosis in the United Kingdom

    Article • BMC Public Health, June 2020, Springer Science + Business Media

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  9. Reactivation of Epstein–Barr virus by a dual-responsive fluorescent EBNA1-targeting agent with Zn 2+ -chelating function

    Article • Proceedings of the National Academy of Sciences, December 2019, Proceedings of the National Academy of Sciences

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  10. Multilaboratory Assessment of Epstein-Barr Virus Serologic Assays: the Case for Standardization

    Article • Journal of Clinical Microbiology, August 2019, ASM Journals

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  11. Vesicle-bound EBV-BART13-3p miRNA in circulation distinguishes nasopharyngeal from other head and neck cancer and asymptomatic EBV-infections

    Article • International Journal of Cancer, December 2018, Wiley

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  12. Establishment and characterization of new tumor xenografts and cancer cell lines from EBV-positive nasopharyngeal carcinoma

    Article • Nature Communications, November 2018, Springer Science + Business Media

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  13. Differences in the Epstein-Barr virus gp350 IgA antibody response are associated with increased risk for co-infection with a second strain of EBV

    Article • The Journal of Infectious Diseases, October 2018, Oxford University Press (OUP)

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  14. Sequence Variation of Epstein-Barr Virus: Viral Types, Geography, Codon Usage, and Diseases

    Article • Journal of Virology, August 2018, ASM Journals

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  15. Curcuminoids as EBV Lytic Activators for Adjuvant Treatment in EBV-Positive Carcinomas

    Article • Cancers, March 2018, MDPI AG

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  16. Epstein–Barr Virus Gene BARF1 Expression is Regulated by the Epithelial Differentiation Factor ΔNp63α in Undifferentiated Nasopharyngeal Carcinoma

    Article • Cancers, March 2018, MDPI AG

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  17. Patterns of Interindividual Variability in the Antibody Repertoire Targeting Proteins Across the Epstein-Barr Virus Proteome

    Article • The Journal of Infectious Diseases, March 2018, Oxford University Press (OUP)

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  18. Correction: Quantifying exosome secretion from single cells reveals a modulatory role for GPCR signaling

    Article • Journal of Cell Biology, January 2018, Rockefeller University Press

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  19. Quantifying exosome secretion from single cells reveals a modulatory role for GPCR signaling

    Article • Journal of Cell Biology, January 2018, Rockefeller University Press

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  20. Identification of a Novel, EBV-Based Antibody Risk Stratification Signature for Early Detection of Nasopharyngeal Carcinoma in Taiwan

    Article • Clinical Cancer Research, January 2018, American Association for Cancer Research (AACR)

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  21. Detecting EBV in Nasal or Nasopharyngeal Swabs of NPC Patients

    Article • Journal of Medical Virology, September 2017, Wiley

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  22. Cytolytic virus activation therapy and treatment monitoring for Epstein-Barr virus associated nasopharyngeal carcinoma in a mouse tumor model

    Article • Journal of Medical Virology, August 2017, Wiley

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  23. Seroprevalence of IgA anti Epstein-Barr virus is high among family members of nasopharyngeal cancer patients and individuals presenting with chronic complaints in head and neck area

    Article • PLoS ONE, August 2017, PLOS

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  24. Persistent KSHV Infection Increases EBV-Associated Tumor Formation In Vivo via Enhanced EBV Lytic Gene Expression

    Article • Cell Host & Microbe, July 2017, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  25. Natural Variation of Epstein-Barr Virus Genes, Proteins, and Primary MicroRNA

    Article • Journal of Virology, May 2017, ASM Journals

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  26. Quantitative multi-target RNA profiling in Epstein-Barr virus infected tumor cells

    Article • Journal of Virological Methods, March 2017, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  27. Epstein-Barr–negative MS: a true phenomenon?

    Article • Neurology Neuroimmunology & Neuroinflammation, February 2017, Wolters Kluwer Health

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  28. High Levels of EBV-Encoded RNA 1 (EBER1) Trigger Interferon and Inflammation-Related Genes in Keratinocytes Expressing HPV16 E6/E7

    Article • PLoS ONE, January 2017, PLOS

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  29. Epstein-Barr virus mRNA profiles and viral DNA methylation status in nasopharyngeal brushings from nasopharyngeal carcinoma patients reflect tumor origin

    Article • International Journal of Cancer, September 2016, Wiley

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  30. Human serum antibodies against EBV latent membrane protein 1 cross-react with α-synuclein

    Article • Neurology Neuroimmunology & Neuroinflammation, May 2016, Wolters Kluwer Health

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  31. A2.09 Longitudinal EBV antibody profiling in sle patients reveals patients with lupus nephritis

    Article • Annals of the Rheumatic Diseases, February 2016, BMJ

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  32. Sensing of latent EBV infection through exosomal transfer of 5′pppRNA

    Article • Proceedings of the National Academy of Sciences, January 2016, Proceedings of the National Academy of Sciences

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  33. The Epstein-Barr Virus BART miRNA Cluster of the M81 Strain Modulates Multiple Functions in Primary B Cells

    Article • PLoS Pathogens, December 2015, PLOS

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  34. Possible contributing role of Epstein-Barr virus (EBV) as a cofactor in human papillomavirus (HPV)-associated cervical carcinogenesis

    Article • Journal of Clinical Virology, December 2015, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  35. A single nucleotide polymorphism in the Epstein-Barr virus genome is strongly associated with a high risk of nasopharyngeal carcinoma

    Article • Chinese Journal of Cancer, December 2015, Springer Science + Business Media

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  36. Reduced Transplacental Transfer of a Subset of Epstein-Barr Virus-Specific Antibodies to Neonates of Mothers Infected with Plasmodium falciparum Malaria during Pregnancy

    Article • Clinical and Vaccine Immunology, September 2015, ASM Journals

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp, Dr Saurabh Mehta

  37. Romidepsin induces cell death in cancers associated with Epstein-Barr virus

    Article • International Journal of Cancer, August 2015, Wiley

    Dr Alan KS CHIANG, prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  38. Abstract 2716: Epstein-Barr virus-encoded BARF1 downregulates SMAD4 and increases miR-146a in gastric carcinoma cells

    Article • Cancer Research, August 2015, American Association for Cancer Research (AACR)

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  39. Can Epstein-Barr virus DNA load in nasopharyngeal brushings or whole blood predict recurrent nasopharyngeal carcinoma in a non-endemic region? A prospective nationwide study of the Dutch Head and Neck Oncology Cooperative Group

    Article • European Archives of Oto-Rhino-Laryngology, May 2015, Springer Science + Business Media

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  40. Epstein–Barr virus-targeted therapy in nasopharyngeal carcinoma

    Article • Journal of Cancer Research and Clinical Oncology, April 2015, Springer Science + Business Media

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  41. Telomerase Activity Impacts on Epstein-Barr Virus Infection of AGS Cells

    Article • PLoS ONE, April 2015, PLOS

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  42. Aberrant Epstein-Barr virus antibody patterns and chronic lymphocytic leukemia in a Spanish multicentric case-control study

    Article • Infectious Agents and Cancer, February 2015, Springer Science + Business Media

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  43. Epstein-Barr Virus-Specific Humoral Immune Responses in Health and Disease

    Article • January 2015, Springer Science + Business Media

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  44. Exosomal sorting of the viral oncoprotein LMP1 is restrained by TRAF2 association at signalling endosomes

    Article • Journal of Extracellular Vesicles, January 2015, Taylor & Francis

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  45. Epstein-Barr virus BARF1-induced NFκB/miR-146a/SMAD4 alterations in stomach cancer cells

    Article • Oncotarget, November 2014, Impact Journals, LLC

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  46. Therapeutic implications of Epstein–Barr virus infection for the treatment of nasopharyngeal carcinoma

    Article • Therapeutics and Clinical Risk Management, September 2014, Taylor & Francis

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp, Herindita Puspitaningtyas

  47. Nontemplated Nucleotide Additions Distinguish the Small RNA Composition in Cells from Exosomes

    Article • Cell Reports, September 2014, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  48. Action of HDAC and proteasome inhibitors in EBV-driven B cell lymphoma

    Article • British Journal of Haematology, August 2014, Wiley

    Dr Alan KS CHIANG, prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  49. Current Status of Cancer Care for Young Patients with Nasopharyngeal Carcinoma in Jakarta, Indonesia

    Article • PLoS ONE, July 2014, PLOS

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  50. Hypothesis: A role for EBV-induced molecular mimicry in Parkinson's disease

    Article • Parkinsonism & Related Disorders, July 2014, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  51. Epstein-Barr virus viral load and serology in childhood non-Hodgkin's lymphoma and chronic inflammatory conditions in Uganda: Implications for disease risk and characteristics

    Article • Journal of Medical Virology, June 2014, Wiley

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  52. P0126 Cytolytic virus activation therapy for epstein-barr virus driven tumours

    Article • European Journal of Cancer, May 2014, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  53. Epstein-Barr Virus Serology as a Potential Screening Marker for Nasopharyngeal Carcinoma among High-Risk Individuals from Multiplex Families in Taiwan

    Article • Cancer Epidemiology Biomarkers & Prevention, April 2014, American Association for Cancer Research (AACR)

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  54. BamHI-A rightward frame 1, an Epstein-Barr virus-encoded oncogene and immune modulator

    Article • Reviews in Medical Virology, August 2013, Wiley

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  55. Epstein-Barr Virus-Encoded BARF1 Promotes Proliferation of Gastric Carcinoma Cells through Regulation of NF- B

    Article • Journal of Virology, July 2013, ASM Journals

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  56. Primary Treatment Results of Nasopharyngeal Carcinoma (NPC) in Yogyakarta, Indonesia

    Article • PLoS ONE, May 2013, PLOS

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  57. Epstein-Barr Virus DNA Load in Nasopharyngeal Brushings and Whole Blood in Nasopharyngeal Carcinoma Patients before and after Treatment

    Article • Clinical Cancer Research, March 2013, American Association for Cancer Research (AACR)

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  58. Lower mortality from nasopharyngeal cancer in The Netherlands since 1970 with differential incidence trends in histopathology

    Article • Oral Oncology, March 2013, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  59. Virus-modified exosomes for targeted RNA delivery; A new approach in nanomedicine

    Article • Advanced Drug Delivery Reviews, March 2013, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  60. Analysis of Viral MicroRNA Exchange via Exosomes In Vitro and In Vivo

    Article • January 2013, Springer Science + Business Media

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  61. Characterization of ELISA detection of broad-spectrum anti-Epstein-Barr virus antibodies associated with nasopharyngeal carcinoma

    Article • Journal of Medical Virology, December 2012, Wiley

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  62. Agreement between diagnoses of childhood lymphoma assigned in Uganda and by an international reference laboratory

    Article • Clinical Epidemiology, December 2012, Taylor & Francis

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  63. Epstein-Barr Virus-Encoded BARF1 Protein is a Decoy Receptor for Macrophage Colony Stimulating Factor and Interferes with Macrophage Differentiation and Activation

    Article • Viral Immunology, December 2012, Mary Ann Liebert Inc

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  64. Cyclin D1 overexpression supports stable EBV infection in nasopharyngeal epithelial cells

    Article • Proceedings of the National Academy of Sciences, November 2012, Proceedings of the National Academy of Sciences

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  65. Development of a Non-Invasive Method, Multiplex Methylation Specific PCR (MMSP), for Early Diagnosis of Nasopharyngeal Carcinoma

    Article • PLoS ONE, November 2012, PLOS

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  66. Persistence of Epstein-Barr Virus in Self-Reactive Memory B Cells

    Article • Journal of Virology, September 2012, ASM Journals

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  67. Epstein-Barr Virus Transcription Activator R Upregulates BARF1 Expression by Direct Binding to Its Promoter, Independent of Methylation

    Article • Journal of Virology, August 2012, ASM Journals

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  68. Cytolytic Virus Activation Therapy for Epstein-Barr Virus-Driven Tumors

    Article • Clinical Cancer Research, July 2012, American Association for Cancer Research (AACR)

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  69. Nasopharyngeal carcinoma in Indonesia: epidemiology, incidence,signs, and symptoms at presentation

    Article • Chinese Journal of Cancer, April 2012, Editorial Office of Chinese Journal of Cancer

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  70. EBNA3B-deficient EBV promotes B cell lymphomagenesis in humanized mice and is found in human tumors

    Article • Journal of Clinical Investigation, April 2012, American Society for Clinical Investigation

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  71. Seroreactivity against Epstein-Barr virus (EBV) among first-degree relatives of sporadic EBV-associated nasopharyngeal carcinoma in Indonesia

    Article • Journal of Medical Virology, March 2012, Wiley

    Professor Nawi Ng, prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  72. Short-Term Effect of Different Teaching Methods on Nasopharyngeal Carcinoma for General Practitioners in Jakarta, Indonesia

    Article • PLoS ONE, March 2012, PLOS

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  73. Activation of lytic cycle of Epstein‐Barr virus by suberoylanilide hydroxamic acid leads to apoptosis and tumor growth suppression of nasopharyngeal carcinoma

    Article • International Journal of Cancer, March 2012, Wiley

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  74. Early Age at Time of Primary Epstein–Barr Virus Infection Results in Poorly Controlled Viral Infection in Infants From Western Kenya: Clues to the Etiology of Endemic Burkitt Lymphoma

    Article • The Journal of Infectious Diseases, February 2012, Oxford University Press (OUP)

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  75. Intracellular signaling controlled by the endosomal-exosomal pathway

    Article • Communicative & Integrative Biology, January 2012, Taylor & Francis

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  76. Variable EBV DNA Load Distributions and Heterogeneous EBV mRNA Expression Patterns in the Circulation of Solid Organ versus Stem Cell Transplant Recipients

    Article • Clinical and Developmental Immunology, January 2012, Hindawi Publishing Corporation

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  77. Association of innate immune activation with latent Epstein-Barr virus in active MS lesions

    Article • Neurology, December 2011, Wolters Kluwer Health

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  78. Viral miRNAs exploiting the endosomal–exosomal pathway for intercellular cross-talk and immune evasion

    Article • Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, November 2011, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  79. Contributions of the Epstein-Barr Virus EBNA1 Protein to Gastric Carcinoma

    Article • Journal of Virology, October 2011, ASM Journals

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  80. A Novel Persistence Associated EBV miRNA Expression Profile Is Disrupted in Neoplasia

    Article • PLoS Pathogens, August 2011, PLOS

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  81. Epstein-Barr virus in the multiple sclerosis brain: a controversial issue--report on a focused workshop held in the Centre for Brain Research of the Medical University of Vienna, Austria

    Article • Brain, August 2011, Oxford University Press (OUP)

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  82. Can an online clinical data management service help in improving data collection and data quality in a developing country setting?

    Article • Trials, August 2011, Springer Science + Business Media

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  83. LMP1 association with CD63 in endosomes and secretion via exosomes limits constitutive NF-κB activation

    Article • The EMBO Journal, April 2011, Wiley

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  84. A human tumor virus extends its reach

    Article • Future Virology, April 2011, Future Medicine

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  85. Humoral immune responses to Epstein-Barr virus encoded tumor associated proteins and their putative extracellular domains in nasopharyngeal carcinoma patients and regional controls

    Article • Journal of Medical Virology, February 2011, Wiley

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  86. Epstein–Barr Virus nuclear antigen 1 (EBNA1) confers resistance to apoptosis in EBV-positive B-lymphoma cells through up-regulation of survivin

    Article • Virology, February 2011, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  87. Epigenetic markers for early detection of nasopharyngeal carcinoma in a high risk population

    Article • Molecular Cancer, January 2011, Springer Science + Business Media

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  88. Purified Hexameric Epstein-Barr Virus-Encoded BARF1 Protein for Measuring Anti-BARF1 Antibody Responses in Nasopharyngeal Carcinoma Patients

    Article • Clinical and Vaccine Immunology, December 2010, ASM Journals

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  89. Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph

    Article • Haematologica, November 2010, Ferrata Storti Foundation (Haematologica)

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  90. Combination of Epstein–Barr virus scaffold (BdRF1/VCA-p40) and small capsid protein (BFRF3/VCA-p18) into a single molecule for improved serodiagnosis of acute and malignant EBV-driven disease

    Article • Journal of Virological Methods, October 2010, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  91. Serological and virological investigation of the role of the herpesviruses EBV, CMV and HHV‐6 in post‐infective fatigue syndrome

    Article • Journal of Medical Virology, September 2010, Wiley

    Louis Flamand, prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  92. Exosomes

    Article • Communicative & Integrative Biology, September 2010, Taylor & Francis

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  93. No evidence for intrathecal IgG synthesis to Epstein Barr virus nuclear antigen-1 in multiple sclerosis

    Article • Journal of Clinical Virology, September 2010, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  94. Functional delivery of viral miRNAs via exosomes

    Article • Proceedings of the National Academy of Sciences, March 2010, Proceedings of the National Academy of Sciences

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  95. Epstein-Barr virus infection in immortalized nasopharyngeal epithelial cells: Regulation of infection and phenotypic characterization

    Article • International Journal of Cancer, January 2010, Wiley

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  96. Risk of classical Kaposi sarcoma by plasma levels of Epstein-Barr virus antibodies, sCD26, sCD23 and sCD30

    Article • Infectious Agents and Cancer, January 2010, Springer Science + Business Media

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  97. Elevated anti-Zta IgG levels and EBV viral load are associated with site of tumor presentation in endemic Burkitt's lymphoma patients: a case control study

    Article • Infectious Agents and Cancer, January 2010, Springer Science + Business Media

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  98. Conserved mutation of Epstein-Barr virus-encoded BamHI-A Rightward Frame-1 (BARF1) gene in Indonesian nasopharyngeal carcinoma

    Article • Infectious Agents and Cancer, January 2010, Springer Science + Business Media

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  99. Epstein Barr virus is not a characteristic feature in the central nervous system in established multiple sclerosis

    Article • Brain, November 2009, Oxford University Press (OUP)

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  100. Epstein-Barr Virus Latent Membrane Protein 1 is not Associated with Vessel Density nor with Hypoxia Inducible Factor 1 Alpha Expression in Nasopharyngeal Carcinoma Tissue

    Article • Head and Neck Pathology, November 2009, Springer Science + Business Media

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  101. A Phase I Trial of Epstein-Barr Virus Gp350 Vaccine for Children With Chronic Kidney Disease Awaiting Transplantation

    Article • Transplantation, October 2009, Wolters Kluwer Health

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  102. 8528 Epstein-Barr virus quantification and aberrant host DNA methylation pattern as marker for nasopharyngeal carcinoma in non-invasive nasopharyngeal brushings

    Article • European Journal of Cancer Supplements, September 2009, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  103. Stage-Specific Inhibition of MHC Class I Presentation by the Epstein-Barr Virus BNLF2a Protein during Virus Lytic Cycle

    Article • PLoS Pathogens, June 2009, PLOS

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  104. Epstein-Barr Virus Latency in B Cells Leads to Epigenetic Repression and CpG Methylation of the Tumour Suppressor Gene Bim

    Article • PLoS Pathogens, June 2009, PLOS

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  105. Serological evidence for long-term epstein-barr virus reactivation in children living in a holoendemic malaria region of Kenya

    Article • Journal of Medical Virology, June 2009, Wiley

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  106. Two-Step Epstein-Barr Virus Immunoglobulin A Enzyme-Linked Immunosorbent Assay System for Serological Screening and Confirmation of Nasopharyngeal Carcinoma

    Article • Clinical and Vaccine Immunology, March 2009, ASM Journals

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  107. O.1.5 LMP1 trafficking via the antigen presentation route

    Article • Journal of Clinical Virology, January 2009, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  108. P.021 Native conformation and wild-type sequence of Epstein–Barr virus protein BARF1 are essential for humoral immune responses to BARF1 in nasopharyngeal carcinoma patients

    Article • Journal of Clinical Virology, January 2009, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  109. O.5.7 Detailed characterisation of Epstein–Barr virus (EBV) infected cells in the circulation of organ transplant recipients with persistent high EBV DNA loads

    Article • Journal of Clinical Virology, January 2009, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  110. Comprehensive Profiling of Epstein-Barr Virus MicroRNAs in Nasopharyngeal Carcinoma

    Article • Journal of Virology, December 2008, ASM Journals

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  111. Multiple roles of LMP1 in Epstein-Barr virus induced immune escape

    Article • Seminars in Cancer Biology, December 2008, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  112. Evaluation of commercial EBV RecombLine assay for diagnosis of nasopharyngeal carcinoma

    Article • Journal of Clinical Virology, August 2008, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  113. Reconstitution of Nasopharyngeal Carcinoma-Type EBV Infection Induces Tumorigenicity

    Article • Cancer Research, February 2008, American Association for Cancer Research (AACR)

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  114. Dried-Blood Sampling for Epstein-Barr Virus Immunoglobulin G (IgG) and IgA Serology in Nasopharyngeal Carcinoma Screening

    Article • Journal of Clinical Microbiology, February 2008, ASM Journals

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  115. The DNase of Gammaherpesviruses Impairs Recognition by Virus-Specific CD8+ T Cells through an Additional Host Shutoff Function

    Article • Journal of Virology, December 2007, ASM Journals

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  116. Monitoring of EBV reactivation is justified in patients with aplastic anemia treated with rabbit ATG as a second course of immunosuppression

    Article • Blood, October 2007, American Society of Hematology

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  117. Aberrant Epstein–Barr virus persistence in HIV carriers is characterized by anti-Epstein–Barr virus IgA and high cellular viral loads with restricted transcription

    Article • AIDS, October 2007, Wolters Kluwer Health

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  118. Host shutoff during productive Epstein–Barr virus infection is mediated by BGLF5 and may contribute to immune evasion

    Article • Proceedings of the National Academy of Sciences, February 2007, Proceedings of the National Academy of Sciences

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  119. Native early antigen of Epstein–Barr virus, a promising antigen for diagnosis of nasopharyngeal carcinoma

    Article • Journal of Medical Virology, January 2007, Wiley

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  120. Epstein-Barr virus infection and risk of lymphoma: Immunoblot analysis of antibody responses against EBV-related proteins in a large series of lymphoma subjects and matched controls

    Article • International Journal of Cancer, January 2007, Wiley

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  121. Exosomes released by EBV-infected nasopharyngeal carcinoma cells convey the viral Latent Membrane Protein 1 and the immunomodulatory protein galectin 9

    Article • BMC Cancer, December 2006, Springer Science + Business Media

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  122. Noninvasive diagnosis of nasopharyngeal carcinoma: Nasopharyngeal brushings reveal high Epstein-Barr virus DNA load and carcinoma-specific viral BARF1 mRNA

    Article • International Journal of Cancer, August 2006, Wiley

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  123. Single-Assay Combination of Epstein-Barr Virus (EBV) EBNA1- and Viral Capsid Antigen-p18-Derived Synthetic Peptides for Measuring Anti-EBV Immunoglobulin G (IgG) and IgA Antibody Levels in Sera from Nasopharyngeal Carcinoma Patients: Options for Field ...

    Article • Journal of Clinical Microbiology, April 2006, ASM Journals

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  124. Epstein-Barr virus (EBV) serology for predicting distant metastases in a white juvenile patient with nasopharyngeal carcinoma and no clinical response to EBV lytic induction therapy

    Article • Head & Neck, January 2006, Wiley

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  125. The antibody 2B4 directed against the Epstein–Barr virus (EBV)-encoded nuclear antigen 1 (EBNA1) detects MAGE-4: implications for studies on the EBV association of human cancers

    Article • The Journal of Pathology, January 2006, Wiley

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  126. Morphological Evidence of an Activated Cytotoxic T-Cell Infiltrate in EBV-Positive Gastric Carcinoma Preventing Lymph Node Metastases

    Article • The American Journal of Surgical Pathology, January 2006, Wolters Kluwer Health

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  127. Epstein-Barr Virus mRNA Export Factor EB2 Is Essential for Intranuclear Capsid Assembly and Production of gp350

    Article • Journal of Virology, November 2005, ASM Journals

    Dr Henri Gruffat, prof.dr. (emeritus professor) Jaap Michiel Middeldorp, Dr Henri V Gruffat

  128. In Nasopharyngeal Carcinoma Cells, Epstein-Barr Virus LMP1 Interacts with Galectin 9 in Membrane Raft Elements Resistant to Simvastatin

    Article • Journal of Virology, November 2005, ASM Journals

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  129. Diagnostic Value of Measuring Epstein-Barr Virus (EBV) DNA Load and Carcinoma-Specific Viral mRNA in Relation to Anti-EBV Immunoglobulin A (IgA) and IgG Antibody Levels in Blood of Nasopharyngeal Carcinoma Patients from Indonesia

    Article • Journal of Clinical Microbiology, July 2005, ASM Journals

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  130. Role of Sexual Behavior in the Acquisition of Asymptomatic Epstein-Barr Virus Infection

    Article • The Pediatric Infectious Disease Journal, June 2005, Wolters Kluwer Health

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  131. Human Cytomegalovirus Infection of a Severe-Burn Patient: Evidence for Productive Self-Limited Viral Replication in Blood and Lung

    Article • Journal of Clinical Microbiology, May 2005, ASM Journals

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  132. Absence of caspase 3 activation in neoplastic cells of nasopharyngeal carcinoma biopsies predicts rapid fatal outcome

    Article • Modern Pathology, April 2005, Nature

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  133. Expression and analysis of the Epstein-Barr virus BARF1-encoded protein from a tetracycline-regulatable adenovirus system

    Article • Virus Research, April 2005, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  134. Epstein-Barr virus (EBV)-encodedBARF1 gene is expressed in nasopharyngeal carcinoma and EBV-associated gastric carcinoma tissues in the absence of lytic gene expression

    Article • Journal of Medical Virology, January 2005, Wiley

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  135. Comparison of three different serological techniques for primary diagnosis and monitoring of nasopharyngeal carcinoma in two age groups from Tunisia

    Article • Journal of Medical Virology, January 2005, Wiley

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  136. Article • Virology Journal, January 2005, Springer Science + Business Media

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  137. Epstein-Barr Virus Infection in Ex Vivo Tonsil Epithelial Cell Cultures of Asymptomatic Carriers

    Article • Journal of Virology, November 2004, ASM Journals

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  138. The Amino Terminus of Epstein-Barr Virus (EBV) Nuclear Antigen 1 Contains AT Hooks That Facilitate the Replication and Partitioning of Latent EBV Genomes by Tethering Them to Cellular Chromosomes

    Article • Journal of Virology, November 2004, ASM Journals

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  139. Cytomegalovirus (CMV) Inactivation in Breast Milk: Reassessment of Pasteurization and Freeze-Thawing

    Article • Pediatric Research, October 2004, Nature

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  140. Molecular Diversity of Epstein‐Barr Virus IgG and IgA Antibody Responses in Nasopharyngeal Carcinoma: A Comparison of Indonesian, Chinese, and European Subjects

    Article • The Journal of Infectious Diseases, July 2004, Oxford University Press (OUP)

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  141. Molecular Evidence for Rhesus Lymphocryptovirus Infection of Epithelial Cells in Immunosuppressed Rhesus Macaques

    Article • Journal of Virology, April 2004, ASM Journals

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  142. EBV-Positive Gastric Adenocarcinomas: A Distinct Clinicopathologic Entity With a Low Frequency of Lymph Node Involvement

    Article • Journal of Clinical Oncology, February 2004, American Society of Clinical Oncology (ASCO)

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  143. Demonstration of the Burkitt's lymphoma Epstein-Barr virus phenotype in dividing latently infected memory cellsin vivo

    Article • Proceedings of the National Academy of Sciences, December 2003, Proceedings of the National Academy of Sciences

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  144. In vivo transcription of the Epstein-Barr virus (EBV) BamHI-A region without associated in vivo BARF0 protein expression in multiple EBV-associated disorders

    Article • Journal of General Virology, October 2003, Society for General Microbiology

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  145. EBV-positive cutaneous B-cell lymphoproliferative disease after imatinib mesylate

    Article • Blood, August 2003, American Society of Hematology

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  146. Localization of the Epstein-Barr virus protein LMP 1 to exosomes

    Article • Journal of General Virology, July 2003, Society for General Microbiology

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  147. Prenatal Diagnosis of Congenital Human Cytomegalovirus Infection in Amniotic Fluid by Nucleic Acid Sequence-Based Amplification Assay

    Article • Journal of Clinical Microbiology, April 2003, ASM Journals

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  148. Genetic Diversity: Frameshift Mechanisms Alter Coding of a Gene (Epstein-Barr Virus LF3 Gene) That Contains Multiple 102-Base-Pair Direct Sequence Repeats

    Article • Molecular and Cellular Biology, March 2003, ASM Journals

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  149. Human cytomegalovirus immediate-early mRNAemia versus pp65 antigenemia for guiding pre-emptive therapy in children and young adults undergoing hematopoietic stem cell transplantation: a prospective, randomized, open-label trial

    Article • Blood, February 2003, American Society of Hematology

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  150. Generation of an adenoviral vector containing an addition of a heterologous ligand to the serotype 3 fiber knob

    Article • Cancer Gene Therapy, January 2003, Nature

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  151. Pathogenic roles for Epstein–Barr virus (EBV) gene products in EBV-associated proliferative disorders

    Article • Critical Reviews in Oncology/Hematology, January 2003, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  152. Quantitative Epstein-Barr virus (EBV) serology in lung transplant recipients with primary EBV infection and/or post-transplant lymphoproliferative disease

    Article • Journal of Medical Virology, December 2002, Wiley

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  153. Epstein–Barr virus replication in tongue epithelial cells

    Article • Journal of General Virology, December 2002, Society for General Microbiology

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  154. Comparison of Quantitative Competitive PCR with LightCycler-Based PCR for Measuring Epstein-Barr Virus DNA Load in Clinical Specimens

    Article • Journal of Clinical Microbiology, November 2002, ASM Journals

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  155. Molecular diagnosis of viral infections in renal transplant recipients

    Article • Current Opinion in Nephrology & Hypertension, November 2002, Wolters Kluwer Health

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  156. Antibody responses to Epstein-Barr virus-encoded latent membrane protein-1 (LMP1) and expression of LMP1 in juvenile Hodgkin's disease

    Article • Journal of Medical Virology, September 2002, Wiley

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  157. A Rapid and Reliable Enzyme Immunoassay PCR-Based Screening Method to Identify EBV-Carrying Gastric Carcinomas

    Article • Modern Pathology, August 2002, Wolters Kluwer Health

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  158. Evaluation of the NucliSens CMV pp67 assay for detection and monitoring of human cytomegalovirus infection after allogeneic stem cell transplantation

    Article • Bone Marrow Transplantation, August 2002, Nature

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  159. Detection of late pp67-mRNA by NASBA in peripheral blood for the diagnosis of human cytomegalovirus disease in AIDS patients

    Article • Journal of Clinical Virology, July 2002, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  160. Absence of elevated anti- -synuclein and anti-EBV latent membrane protein antibodies in PD

    Article • Neurology, May 2002, Wolters Kluwer Health

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  161. High Epstein–Barr virus (EBV) DNA loads in HIV-infected patients: correlation with antiretroviral therapy and quantitative EBV serology

    Article • AIDS, May 2002, Wolters Kluwer Health

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  162. Identification and prevalence of CD8+ T-cell responses directed against Epstein-Barr virus-encoded latent membrane protein 1 and latent membrane protein 2

    Article • International Journal of Cancer, March 2002, Wiley

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  163. Multiplex real-time NASBA for monitoring expression dynamics of human cytomegalovirus encoded IE1 and pp67 RNA

    Article • Journal of Clinical Virology, February 2002, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  164. TREATMENT OF POSTTRANSPLANT LYMPHOPROLIFERATIVE DISEASE WITH RITUXIMAB

    Article • Transplantation, January 2002, Wolters Kluwer Health

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  165. Role of Epstein-Barr Virus DNA Load Monitoring in Prevention and Early Detection of Post-transplant Lymphoproliferative Disease

    Article • Leukemia & Lymphoma, January 2002, Taylor & Francis

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  166. High numbers of granzyme B/CD8-positive tumour-infiltrating lymphocytes in nasopharyngeal carcinoma biopsies predict rapid fatal outcome in patients treated with curative intent

    Article • The Journal of Pathology, January 2002, Wiley

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  167. Different profiles of cytomegalovirus RNA transcripts and anti-cytomegalovirus IgM antibodies in renal transplant recipients

    Article • Journal of Clinical Virology, December 2001, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  168. Human Cytomegalovirus Immediate‐Early Messenger RNA in Blood of Pregnant Women with Primary Infection and of Congenitally Infected Newborns

    Article • The Journal of Infectious Diseases, October 2001, Oxford University Press (OUP)

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  169. Differential Immunogenicity of Epstein-Barr Virus Latent-Cycle Proteins for Human CD4+ T-Helper 1 Responses

    Article • Journal of Virology, September 2001, ASM Journals

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  170. Expression Dynamics of Human Cytomegalovirus Immune Evasion GenesUS3, US6,andUS11in the Blood of Lung Transplant Recipients

    Article • The Journal of Infectious Diseases, August 2001, Oxford University Press (OUP)

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  171. Quantitative competitive NASBA for measuring mRNA expression levels of the immediate early 1, late pp67, and immune evasion genes US3, US6 and US11 in cells infected with human cytomegalovirus

    Article • Journal of Virological Methods, August 2001, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  172. Toward Standardization of Epstein-Barr Virus DNA Load Monitoring: Unfractionated Whole Blood as Preferred Clinical Specimen

    Article • Journal of Clinical Microbiology, April 2001, ASM Journals

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  173. Activity of the EBNA1 promoter associated with lytic replication (Fp) in Epstein-Barr virus associated disorders

    Article • Molecular Pathology, April 2001, BMJ

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  174. Is Epstein-Barr virus present in the CNS of patients with MS?

    Article • Neurology, March 2001, Wolters Kluwer Health

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  175. Frequent monitoring of Epstein-Barr virus DNA load in unfractionated whole blood is essential for early detection of posttransplant lymphoproliferative disease in high-risk patients

    Article • Blood, March 2001, American Society of Hematology

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  176. Functional CD4+ and CD8+ T-Cell Responses Induced by Autologous Mitomycin C Treated Epstein–Barr Virus Transformed Lymphoblastoid Cell Lines

    Article • Cellular Immunology, February 2001, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  177. Patients at risk for post-transplant lymphoproliferative disease can be identified in the first months after lung transplantation by quantitative-competitive-EBV-PCR

    Article • The Journal of Heart and Lung Transplantation, February 2001, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  178. Direct Quantification of Human Cytomegalovirus Immediate-Early and Late mRNA Levels in Blood of Lung Transplant Recipients by Competitive Nucleic Acid Sequence-Based Amplification

    Article • Journal of Clinical Microbiology, January 2001, ASM Journals

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  179. Use of CMV transcripts for monitoring of CMV infections in transplant recipients

    Article • International Journal of Antimicrobial Agents, December 2000, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  180. Production monitoring and purification of EBV encoded latent membrane protein 1 expressed and secreted by recombinant baculovirus infected insect cells

    Article • Journal of Virological Methods, November 2000, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  181. Bioreactor-Scale Production and One-Step Purification of Epstein–Barr Nuclear Antigen 1 Expressed in Baculovirus-Infected Insect Cells

    Article • Protein Expression and Purification, November 2000, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  182. Human Cytomegalovirus Virions Differentially Incorporate Viral and Host Cell RNA during the Assembly Process

    Article • Journal of Virology, October 2000, ASM Journals

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  183. EVALUATION OF HUMAN CYTOMEGALOVIRUS GENE EXPRESSION IN THORACIC ORGAN TRANSPLANT RECIPIENTS USING NUCLEIC ACID SEQUENCE-BASED AMPLIFICATION

    Article • Transplantation, October 2000, Wolters Kluwer Health

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  184. Hairy Leukoplakia: an Unusual Combination of Transforming and Permissive Epstein-Barr Virus Infections

    Article • Journal of Virology, August 2000, ASM Journals

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  185. Efficacy of ionizing radiation combined with adenoviral p53 therapy in EBV‐positive nasopharyngeal carcinoma

    Article • International Journal of Cancer, August 2000, Wiley

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  186. Direct Immunosuppressive Effects of EBV-Encoded Latent Membrane Protein 1

    Article • The Journal of Immunology, July 2000, The American Association of Immunologists

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  187. All infiltrating T-lymphocytes in Hodgkin's disease express immunohistochemically detectable T-cell receptor zeta-chains in situ

    Article • Histopathology, June 2000, Wiley

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  188. Expression of the transforming Epstein-Barr virus BARF1 gene in EBV-carrying gastric adenocarcinomas

    Article • Gastroenterology, April 2000, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  189. Early detection of cytomegalovirus in renal transplant recipients: comparison of PCR, NASBA, pp65 antigenemia, and viral culture

    Article • Transplantation Proceedings, February 2000, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  190. Quantitative immunohistochemical analysis of cytokine profiles in Epstein-Barr virus-positive and -negative cases of Hodgkin's disease

    Article • The Journal of Pathology, February 2000, Wiley

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  191. Sensitive detection of cytomegalovirus infection in transplant recipients using nucleic acid sequence-based amplification

    Article • Transplantation Proceedings, February 2000, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  192. Quantitative immunohistochemical analysis of cytokine profiles in Epstein–Barr virus‐positive and ‐negative cases of Hodgkin's disease

    Article • The Journal of Pathology, February 2000, Wiley

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  193. Efficacy of ionizing radiation combined with adenoviralp53 therapy in EBV-positive nasopharyngeal carcinoma

    Article • International Journal of Cancer, January 2000, Wiley

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  194. EARLY DETECTION OF HUMAN CYTOMEGALOVIRUS INFECTION AFTER KIDNEY TRANSPLANTATION BY NUCLEIC ACID SEQUENCE-BASED AMPLIFICATION1

    Article • Transplantation, May 1999, Wolters Kluwer Health

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  195. Restricted Low‐Level Human Antibody Responses against Epstein‐Barr Virus (EBV)–Encoded Latent Membrane Protein 1 in a Subgroup of Patients with EBV‐Associated Diseases

    Article • The Journal of Infectious Diseases, May 1999, Oxford University Press (OUP)

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  196. Direct quantification of human cytomegalovirus (HCMV) immediate early and late mRNA levels in the blood of HCMV-infected individuals using competetive NASBA

    Article • Journal of Clinical Virology, April 1999, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  197. Expression of Epstein-Barr virus (EBV) transcripts encoding homologues to important human proteins in diverse EBV associated diseases [published erratum appears in Mol Pathol 1999 Oct;52(5):305]

    Article • Molecular Pathology, April 1999, BMJ

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  198. Nucleic acid sequence-based amplification: a new technique for monitoring cytomegalovirus infection in transplant recipients

    Article • Transplantation Proceedings, February 1999, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  199. Diagnostic Value of Nucleic-Acid-Sequence- Based Amplification for the Detection of Cytomegalovirus Infection in Renal and Liver Transplant Recipients

    Article • Intervirology, January 1999, Karger Publishers

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  200. Epstein-Barr virus expression within keratinizing nasopharyngeal carcinoma

    Article • Journal of Medical Virology, July 1998, Wiley

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  201. Evaluation of a new method for early detection of active cytomegalovirus infections. A study in kidney transplant recipients

    Article • Transplant International, June 1998, Wiley

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  202. Physical association between the EBV protein EBNA-1 and P32/TAP/hyaluronectin

    Article • Journal of Biomedical Science, May 1998, Springer Science + Business Media

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  203. Physical Association between the EBV Protein EBNA-1 and P32/TAP/Hyaluronectin

    Article • Journal of Biomedical Science, January 1998, Springer Science + Business Media

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  204. A Major DNA Binding Protein Encoded by BALF2 Open Reading Frame of Epstein–Barr Virus (EBV) Forms a Complex with Other EBV DNA-Binding Proteins: DNAase, EA-D, and DNA Polymerase

    Article • Virology, December 1997, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  205. Presence of Epstein-Barr virus latency type III at the single cell level in post-transplantation lymphoproliferative disorders and AIDS related lymphomas.

    Article • Journal of Clinical Pathology, November 1997, BMJ

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  206. P32/TAP, a Cellular Protein That Interacts with EBNA-1 of Epstein–Barr Virus

    Article • Virology, September 1997, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  207. Fine-mapping of human and mouse/rat antibody binding to Epstein-Barr virus nuclear antigen-1 (EBNA-1): Linear and conformational epitopes

    Article • Immunology Letters, May 1997, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  208. Epstein Barr virus specific antibody patterns in lung transplant recipients with post transplant lymphoproliferative disease

    Article • Immunology Letters, May 1997, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  209. Epstein Barr virus encoded latent membrane protein (LMP-1) escapes from humoral immune control

    Article • Immunology Letters, May 1997, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  210. Expression of epstein-barr virus encoded nuclear antigen 1 in benign and malignant tissues harbouring EBV.

    Article • Journal of Clinical Pathology, November 1996, BMJ

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  211. Molecular species of hepadnavirus core and envelope polypeptides in hepatocyte plasma membrane of woodchucks with acute and chronic viral hepatitis,

    Article • Hepatology, August 1994, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  212. Detection of hepatitis C virus antigen by immuno-histochemical staining: a histological marker of hepatitis C virus infection

    Article • Journal of Hepatology, January 1994, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  213. Expression of epstein-barr-virus-related nuclear antigens and B-cell markers in lymphomas of SIV-immunosuppressed monkeys

    Article • International Journal of Cancer, October 1993, Wiley

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  214. Epstein-Barr Virus Gene Expression in Oral Hairy Leukoplakia

    Article • Virology, August 1993, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  215. Identification and molecular characterization of two diagnostically relevant marker proteins of the Epstein-Barr virus capsid antigen complex

    Article • Journal of Medical Virology, June 1993, Wiley

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  216. Purification and quantification of recombinant Epstein-Barr viral glycoproteins gp350/220 from Chinese hamster ovary cells

    Article • Journal of Chromatography A, May 1992, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  217. Epitope-mapping on the Epstein-Barr virus major capsid protein using systematic synthesis of overlapping oligopeptides

    Article • Journal of Virological Methods, September 1988, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  218. Epstein-Barr virus specific marker molecules for early diagnosis of infectious mononucleosis

    Article • Journal of Virological Methods, September 1988, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  219. Development of an antibody-capture IgM-enzyme-linked immunosorbent assay for diagnosis of acute epstein-barr virus infections

    Article • Journal of Virological Methods, September 1988, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  220. A sensitive enzyme-linked immunosorbent assay for the detection of herpes simplex virus antigens

    Article • Journal of Virological Methods, August 1987, Elsevier

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  221. Killing of Human Cytomegalovirus-Infected Fibroblasts by Antiviral Antibody and Complement

    Article • The Journal of Infectious Diseases, January 1986, Oxford University Press (OUP)

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  222. CYTOMEGALOVIRUS IMMUNITY IN ALLOGENEIC MARROW GRAFTING1

    Article • Transplantation, November 1985, Wolters Kluwer Health

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  223. HLA-DRw6 as a risk factor for active cytomegalovirus but not for herpes simplex virus infection after renal allograft transplantation.

    Article • BMJ, September 1985, BMJ

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  224. Cytomegalovirus (CMV)-infections and hosts’ immunoregulation in liver transplantation

    Article • January 1985, Springer Science + Business Media

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  225. A Stimulatory Role for Cytomegalovirus (CMV) Antibodies in CMV-Specific Lymphocyte Proliferation in vitro

    Article • Intervirology, January 1983, Karger Publishers

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  226. An in vitro System to Study Interactions between Bacteria and Epithelial Cells at the Molecular Level

    Article • Microbiology, January 1983, Society for General Microbiology

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  227. Quantitative Detection of Epstein-Barr Virus DNA in Clinical Specimens by Rapid Real-Time PCR Targeting a Highly Conserved Region of EBNA-1

    Article • Springer Science + Business Media

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  228. Profiling of Epstein-Barr Virus Latent RNA Expression in Clinical Specimens by Gene-Specific Multiprimed cDNA Synthesis and PCR

    Article • Springer Science + Business Media

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp

  229. EBV-positive cutaneous B-cell lymphoproliferative disease after imatinib mesylate (Glivec)

    Article • Springer Science + Business Media

    prof.dr. (emeritus professor) Jaap Michiel Middeldorp