All Stories

  1. Restoration of Megalin-Mediated Clearance of Alveolar Protein as a Novel Therapeutic Approach for Acute Lung Injury

    Article • American Journal of Respiratory Cell and Molecular Biology, November 2017, American Thoracic Society

    Istvan Vadasz

  2. TGF-β inhibits alveolar protein transport by promoting shedding, regulated intramembrane proteolysis, and transcriptional downregulation of megalin

    Article • AJP Lung Cellular and Molecular Physiology, November 2017, American Physiological Society

    Istvan Vadasz

  3. Perturbations to lysyl oxidase expression broadly influence the transcriptome of lung fibroblasts

    Article • Physiological Genomics, August 2017, American Physiological Society

    Istvan Vadasz

  4. Gas Exchange Disturbances Regulate Alveolar Fluid Clearance during Acute Lung Injury

    Article • Frontiers in Immunology, July 2017, Frontiers

    Istvan Vadasz

  5. Keratinocyte growth factor in acute respiratory distress syndrome

    Article • The Lancet Respiratory Medicine, June 2017, Elsevier

    Istvan Vadasz

  6. Stereological monitoring of mouse lung alveolarization from the early postnatal period to adulthood

    Article • AJP Lung Cellular and Molecular Physiology, June 2017, American Physiological Society

    Istvan Vadasz

  7. Hypercapnia Impairs ENaC Cell Surface Stability by Promoting Phosphorylation, Polyubiquitination and Endocytosis of β-ENaC in a Human Alveolar Epithelial Cell Line

    Article • Frontiers in Immunology, May 2017, Frontiers

    Istvan Vadasz

  8. Correction: Detrimental ELAVL-1/HuR-dependent GSK3β mRNA stabilization impairs resolution in acute respiratory distress syndrome

    Article • PLoS ONE, April 2017, PLOS

    Istvan Vadasz

  9. Detrimental ELAVL-1/HuR-dependent GSK3β mRNA stabilization impairs resolution in acute respiratory distress syndrome

    Article • PLoS ONE, February 2017, PLOS

    Istvan Vadasz

  10. Caffeine administration modulates TGF-β signaling but does not attenuate blunted alveolarization in a hyperoxia-based mouse model of bronchopulmonary dysplasia

    Article • Pediatric Research, January 2017, Springer Science + Business Media

    Istvan Vadasz

  11. Standardisation of oxygen exposure in the development of mouse models for bronchopulmonary dysplasia

    Article • Disease Models & Mechanisms, December 2016, The Company of Biologists

    Istvan Vadasz

  12. Tamoxifen dosing for Cre-mediated recombination in experimental bronchopulmonary dysplasia

    Article • Transgenic Research, October 2016, Springer Science + Business Media

    Istvan Vadasz

  13. N-3 vs. n-6 fatty acids differentially influence calcium signalling and adhesion of inflammatory activated monocytes: impact of lipid rafts

    Article • Inflammation Research, July 2016, Springer Science + Business Media

    Istvan Vadasz

  14. Influenza Virus Infects Epithelial Stem/Progenitor Cells of the Distal Lung: Impact on Fgfr2b-Driven Epithelial Repair

    Article • PLoS Pathogens, June 2016, PLOS

    Istvan Vadasz

  15. Macrophage-epithelial paracrine crosstalk inhibits lung edema clearance during influenza infection

    Article • Journal of Clinical Investigation, March 2016, American Society for Clinical Investigation

    Istvan Vadasz

  16. FXYD1 negatively regulates Na+/K+-ATPase activity in lung alveolar epithelial cells

    Article • Respiratory Physiology & Neurobiology, January 2016, Elsevier

    Istvan Vadasz

  17. The H2S-generating enzymes cystathionine β-synthase and cystathionine γ-lyase play a role in vascular development during normal lung alveolarization

    Article • AJP Lung Cellular and Molecular Physiology, October 2015, American Physiological Society

    Professor Heinz Günther Fehrenbach, Istvan Vadasz

  18. High CO2Leads to Na,K-ATPase Endocytosis via c-Jun Amino-Terminal Kinase-Induced LMO7b Phosphorylation

    Article • Molecular and Cellular Biology, September 2015, ASM Journals

    Istvan Vadasz

  19. PPAR-α activation reduced LPS-induced inflammation in alveolar epithelial cells

    Article • Experimental Lung Research, July 2015, Taylor & Francis

    Istvan Vadasz

  20. Collagen and elastin cross-linking is altered during aberrant late lung development associated with hyperoxia

    Article • AJP Lung Cellular and Molecular Physiology, June 2015, American Physiological Society

    Istvan Vadasz

  21. Immunomodulation by lipid emulsions in pulmonary inflammation: a randomized controlled trial

    Article • Critical Care, May 2015, Springer Science + Business Media

    Istvan Vadasz

  22. Lysyl Oxidases Play a Causal Role in Vascular Remodeling in Clinical and Experimental Pulmonary Arterial Hypertension

    Article • Arteriosclerosis Thrombosis and Vascular Biology, May 2014, Wolters Kluwer Health

    Istvan Vadasz

  23. Systemic hydrogen sulfide administration partially restores normal alveolarization in an experimental animal model of bronchopulmonary dysplasia

    Article • AJP Lung Cellular and Molecular Physiology, April 2014, American Physiological Society

    Professor Heinz Günther Fehrenbach, Istvan Vadasz

  24. Transglutaminase 2: a new player in bronchopulmonary dysplasia?

    Article • European Respiratory Journal, March 2014, European Respiratory Society (ERS)

    Istvan Vadasz

  25. Inhaled Granulocyte/Macrophage Colony–Stimulating Factor as Treatment of Pneumonia-associated Acute Respiratory Distress Syndrome

    Article • American Review of Respiratory Disease, March 2014, American Thoracic Society

    Istvan Vadasz

  26. Deregulation of the lysyl hydroxylase matrix cross-linking system in experimental and clinical bronchopulmonary dysplasia

    Article • AJP Lung Cellular and Molecular Physiology, February 2014, American Physiological Society

    Istvan Vadasz

  27. Immunomodulation by fish-oil containing lipid emulsions in murine acute respiratory distress syndrome

    Article • Critical Care, January 2014, Springer Science + Business Media

    Istvan Vadasz

  28. Glucocorticoids Recruit Tgfbr3 and Smad1 to Shift Transforming Growth Factor-β Signaling from the Tgfbr1/Smad2/3 Axis to the Acvrl1/Smad1 Axis in Lung Fibroblasts

    Article • Journal of Biological Chemistry, December 2013, American Society for Biochemistry & Molecular Biology (ASBMB)

    Istvan Vadasz

  29. TGF-β directs trafficking of the epithelial sodium channel ENaC which has implications for ion and fluid transport in acute lung injury

    Article • Proceedings of the National Academy of Sciences, December 2013, Proceedings of the National Academy of Sciences

    Istvan Vadasz

  30. Efficient gene delivery to primary alveolar epithelial cells by nucleofection

    Article • AJP Lung Cellular and Molecular Physiology, December 2013, American Physiological Society

    Istvan Vadasz

  31. Novel concepts of acute lung injury and alveolar-capillary barrier dysfunction

    Article • AJP Lung Cellular and Molecular Physiology, November 2013, American Physiological Society

    Istvan Vadasz

  32. Influenza A matrix protein M2 downregulates CFTR: inhibition of chloride transport by a proton channel of the viral envelope

    Article • AJP Lung Cellular and Molecular Physiology, June 2013, American Physiological Society

    Istvan Vadasz

  33. Impact of Short- and Medium-Chain Fatty Acids on Mitochondrial Function in Severe Inflammation

    Article • Journal of Parenteral and Enteral Nutrition, May 2013, Wiley

    Istvan Vadasz

  34. Chloride transport-driven alveolar fluid secretion is a major contributor to cardiogenic lung edema

    Article • Proceedings of the National Academy of Sciences, May 2013, Proceedings of the National Academy of Sciences

    Istvan Vadasz

  35. Evolutionary Conserved Role of c-Jun-N-Terminal Kinase in CO2-Induced Epithelial Dysfunction

    Article • PLoS ONE, October 2012, PLOS

    Istvan Vadasz

  36. Megalin mediates transepithelial albumin clearance from the alveolar space of intact rabbit lungs

    Article • The Journal of Physiology, October 2012, Wiley

    Istvan Vadasz

  37. Update in Acute Lung Injury and Mechanical Ventilation 2011

    Article • American Review of Respiratory Disease, July 2012, American Thoracic Society

    Istvan Vadasz

  38. Lord of the RING: Ubiquitination and Directed Degradation of Skeletal Muscle in Acute Lung Injury

    Article • American Review of Respiratory Disease, April 2012, American Thoracic Society

    Istvan Vadasz

  39. Hypercapnia: A Nonpermissive Environment for the Lung

    Article • American Journal of Respiratory Cell and Molecular Biology, April 2012, American Thoracic Society

    Dr. Peter H. Sporn, Istvan Vadasz

  40. Ubiquitination and Proteolysis in Acute Lung Injury

    Article • CHEST Journal, March 2012, Elsevier

    Istvan Vadasz

  41. Elevated CO2Levels Cause Mitochondrial Dysfunction and Impair Cell Proliferation

    Article • Journal of Biological Chemistry, September 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Istvan Vadasz

  42. Exudate Macrophages Attenuate Lung Injury by the Release of IL-1 Receptor Antagonist in Gram-negative Pneumonia

    Article • American Review of Respiratory Disease, May 2011, American Thoracic Society

    Istvan Vadasz

  43. Update in Acute Lung Injury and Critical Care 2010

    Article • American Review of Respiratory Disease, May 2011, American Thoracic Society

    Istvan Vadasz

  44. Carbon Monoxide Rapidly Impairs Alveolar Fluid Clearance by Inhibiting Epithelial Sodium Channels

    Article • American Journal of Respiratory Cell and Molecular Biology, December 2009, American Thoracic Society

    Istvan Vadasz

  45. The lectin-like domain of tumor necrosis factor-α improves alveolar fluid balance in injured isolated rabbit lungs*

    Article • Critical Care Medicine, May 2008, Wolters Kluwer Health

    Istvan Vadasz

  46. AMP-activated protein kinase regulates CO2-induced alveolar epithelial dysfunction in rats and human cells by promoting Na,K-ATPase endocytosis

    Article • Journal of Clinical Investigation, January 2008, American Society for Clinical Investigation

    Istvan Vadasz

  47. High CO2 Levels Impair Alveolar Epithelial Function Independently of pH

    Article • PLoS ONE, November 2007, PLOS

    Istvan Vadasz

  48. Alveolar epithelium and Na,K-ATPase in acute lung injury

    Article • Intensive Care Medicine, May 2007, Springer Science + Business Media

    Istvan Vadasz

  49. Tropolysin, a New Oligopeptidase from African Trypanosomes†,‡

    Article • Biochemistry, November 2005, American Chemical Society (ACS)

    Istvan Vadasz

  50. Thrombin Impairs Alveolar Fluid Clearance by Promoting Endocytosis of Na+,K+-ATPase

    Article • American Journal of Respiratory Cell and Molecular Biology, October 2005, American Thoracic Society

    Istvan Vadasz

  51. Oleic Acid Inhibits Alveolar Fluid Reabsorption

    Article • American Review of Respiratory Disease, March 2005, American Thoracic Society

    Istvan Vadasz

  52. Oligopeptidase B from Trypanosoma evansi: A PARASITE PEPTIDASE THAT INACTIVATES ATRIAL NATRIURETIC FACTOR IN THE BLOODSTREAM OF INFECTED HOSTS

    Article • Journal of Biological Chemistry, January 2005, American Society for Biochemistry & Molecular Biology (ASBMB)

    Istvan Vadasz