All Stories

  1. Evaluation of Peptide Ligation Strategies for the Synthesis of the Bivalent Acid-Sensing Ion Channel Inhibitor Hi1a

    Article • Organic Letters, June 2023, American Chemical Society (ACS)

    Ms Hue Tran

  2. Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 function

    Article • Nature Communications, April 2023, Springer Science + Business Media

    Ms Hue Tran

  3. µ-Conotoxins Targeting the Human Voltage-Gated Sodium Channel Subtype NaV1.7

    Article • Toxins, August 2022, MDPI AG

    Ms Hue Tran

  4. On the Utility of Chemical Strategies to Improve Peptide Gut Stability

    Article • Journal of Medicinal Chemistry, April 2022, American Chemical Society (ACS)

    Ms Hue Tran

  5. Structural and functional insights into inhibition of human voltage-gated sodium channels by μ‐conotoxin KIIIA disulfide isomers

    Article • Journal of Biological Chemistry, February 2022, Elsevier

    Ms Hue Tran

  6. Evaluation of Efficient Non-reducing Enzymatic and Chemical Ligation Strategies for Complex Disulfide-Rich Peptides

    Article • Bioconjugate Chemistry, November 2021, American Chemical Society (ACS)

    Ms Hue Tran

  7. The Allosteric Activation of α7 nAChR by α-Conotoxin MrIC Is Modified by Mutations at the Vestibular Site

    Article • Toxins, August 2021, MDPI AG

    Ms Hue Tran

  8. Chemical Synthesis of TFF3 Reveals Novel Mechanistic Insights and a Gut-Stable Metabolite

    Article • Journal of Medicinal Chemistry, June 2021, American Chemical Society (ACS)

    Ms Hue Tran

  9. Improving the Gastrointestinal Stability of Linaclotide

    Article • Journal of Medicinal Chemistry, May 2021, American Chemical Society (ACS)

    Ms Hue Tran

  10. Discovery, Pharmacological Characterisation and NMR Structure of the Novel µ-Conotoxin SxIIIC, a Potent and Irreversible NaV Channel Inhibitor

    Article • Biomedicines, October 2020, MDPI AG

    Ms Hue Tran

  11. Manipulation of a spider peptide toxin alters its affinity for lipid bilayers and potency and selectivity for voltage-gated sodium channel subtype 1.7

    Article • Journal of Biological Chemistry, March 2020, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Alexander Mueller, Ms Hue Tran

  12. Enzymatic Ligation of a Pore Blocker Toxin and a Gating Modifier Toxin: Creating Double-Knotted Peptides with Improved Sodium Channel NaV1.7 Inhibition

    Article • Bioconjugate Chemistry, December 2019, American Chemical Society (ACS)

    Ms Hue Tran

  13. Novel heterodimeric ion channel modulators derived from conotoxins and spider toxins

    Article • University of Queensland Library

    Ms Hue Tran