All Stories

  1. Exploring the human gut microbiota targets in relation to the use of contemporary antidepressants

    Article • Journal of Affective Disorders, January 2024, Elsevier

    Dr. Hsi-Chung Chen

  2. GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors

    Article • American Journal of Psychiatry, October 2023, American Psychiatric Association

    Anna Docherty, Dr. Hsi-Chung Chen

  3. Sleep and Nutrition In Older Adults (The Yialn Study)

    Article • The journal of nutrition health & aging, September 2023, Springer Science + Business Media

    Dr. Hsi-Chung Chen

  4. Comorbid insomnia and sleepiness predict mortality (The Yilan Study)

    Article • The Journals of Gerontology Series A, August 2023, Oxford University Press (OUP)

    Dr. Hsi-Chung Chen

  5. Association of polygenic score and the involvement of cholinergic and glutamatergic pathways with lithium treatment response in patients with bipolar disorder

    Article • Molecular Psychiatry, July 2023, Springer Science + Business Media

    Dr. Hsi-Chung Chen

  6. Bedtime and Cardiac Autonomic Function (The Yilan study)

    Article • Chronobiology International, May 2023, Taylor & Francis

    Dr. Hsi-Chung Chen

  7. The associations between working conditions and subjective sleep quality among female migrant care workers

    Article • Frontiers in Public Health, April 2023, Frontiers

    Dr. Hsi-Chung Chen

  8. Identification of Novel, Replicable Genetic Risk Loci for Suicidal Thoughts and Behaviors Among US Military Veterans

    Article • JAMA Psychiatry, December 2022, American Medical Association (AMA)

    Dr. Hsi-Chung Chen, Fernando Fernandez-Aranda

  9. Exploration of the relationship between gut microbiota and fecal microRNAs in patients with major depressive disorder

    Article • Scientific Reports, December 2022, Springer Science + Business Media

    Dr. Hsi-Chung Chen

  10. The association of personality polygenic risk score, psychosocial protective factors and suicide attempt in mood disorder

    Article • Journal of Psychiatric Research, October 2022, Elsevier

    Dr. Hsi-Chung Chen

  11. AD-8 and Item Response Theory (The Yilan Study)

    Article • Psychogeriatrics, August 2022, Wiley

    Dr. Hsi-Chung Chen

  12. Correction: Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients

    Article • Translational Psychiatry, July 2022, Springer Science + Business Media

    Dr. Hsi-Chung Chen

  13. Personality mediates the association between juvenile conduct problems and adulthood mood disorders

    Article • Scientific Reports, May 2022, Springer Science + Business Media

    Dr. Hsi-Chung Chen

  14. Using polygenic scores and clinical data for bipolar disorder patient stratification and lithium response prediction: machine learning approach – CORRIGENDUM

    Article • The British Journal of Psychiatry, May 2022, Royal College of Psychiatrists

    Dr. Hsi-Chung Chen

  15. Volunteering, Insomnia and Subjective Well-Being (The Yilan Study)

    Article • BMC Geriatrics, April 2022, Springer Science + Business Media

    Dr. Hsi-Chung Chen

  16. Hypnotics use and sleep quality (The Yilan Study)

    Article • Nature and Science of Sleep, April 2022, Taylor & Francis

    Dr. Hsi-Chung Chen

  17. Stress Susceptibility Moderates the Relationship Between Eveningness Preference and Poor Sleep Quality in Non-Acute Mood Disorder Patients and Healthy Controls

    Article • Nature and Science of Sleep, April 2022, Taylor & Francis

    Dr. Hsi-Chung Chen

  18. Characterization of clinical features and comorbidities between bipolar affective disorder with and without depressive episodes

    Article • Psychological Medicine, March 2022, Cambridge University Press

    Dr. Hsi-Chung Chen

  19. The Influence of Research Follow-Up during COVID-19 Pandemic on Mental Distress and Resilience: A Multicenter Cohort Study of Treatment-Resistant Depression

    Article • International Journal of Environmental Research and Public Health, March 2022, MDPI AG

    Dr. Hsi-Chung Chen

  20. Using polygenic scores and clinical data for bipolar disorder patient stratification and lithium response prediction: machine learning approach

    Article • The British Journal of Psychiatry, February 2022, Royal College of Psychiatrists

    Dr. Hsi-Chung Chen

  21. Investigating the phenotypic and genetic associations between personality traits and suicidal behavior across major mental health diagnoses

    Article • European Archives of Psychiatry and Clinical Neuroscience, February 2022, Springer Science + Business Media

    Dr. Hsi-Chung Chen

  22. Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients

    Article • Translational Psychiatry, November 2021, Springer Science + Business Media

    Dr. Hsi-Chung Chen

  23. Subgrouping time-dependent prescribing patterns of first-onset major depressive episodes by psychotropics dissection

    Article • World Journal of Psychiatry, November 2021, Baishideng Publishing Group Co., Limited (formerly WJG Press)

    Dr. Hsi-Chung Chen

  24. Poor Sleep Quality & RCSSQ-4 (The Yilan Study)

    Article • Nature and Science of Sleep, November 2021, Taylor & Francis

    Dr. Hsi-Chung Chen

  25. Depression, Anxiety & Health Services (The Yilan Study)

    Article • Journal of the Formosan Medical Association, November 2021, Elsevier

    Dr. Hsi-Chung Chen

  26. The Genetic Architecture of Depression in Individuals of East Asian Ancestry

    Article • JAMA Psychiatry, November 2021, American Medical Association (AMA)

    Dr. Hsi-Chung Chen

  27. HLA-DRB1 and HLA-DQB1 genetic diversity modulates response to lithium in bipolar affective disorders

    Article • Scientific Reports, September 2021, Springer Science + Business Media

    Dr. Hsi-Chung Chen

  28. Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders and known risk factors

    Article • Biological Psychiatry, September 2021, Elsevier

    Dr. Hsi-Chung Chen, Fernando Fernandez-Aranda

  29. Hand Grip Strength and Walking Speed (The Yilan Study)

    Article • BMC Geriatrics, July 2021, Springer Science + Business Media

    Dr. Hsi-Chung Chen

  30. Volunteering and Health Outcomes (The Yilan Study)

    Article • Quality of Life Research, July 2021, Springer Science + Business Media

    Dr. Hsi-Chung Chen

  31. Premenstrual dysphoric symptoms and lifetime suicide experiences in patients with mood disorder

    Article • General Hospital Psychiatry, July 2021, Elsevier

    Dr. Hsi-Chung Chen

  32. Visualizing Patterns of Medication Switching Among Major Depressive Patients with Various Stability and Difficulty to Treatments

    Article • June 2021, Taylor & Francis

    Dr. Hsi-Chung Chen

  33. Differential Co-Occurring Patterns Between Depressive Symptomatology and Sleep-Wake-Related Disturbances in Mood Disorders

    Article • Nature and Science of Sleep, April 2021, Taylor & Francis

    Dr. Hsi-Chung Chen

  34. Prediction of lithium response using genomic data

    Article • Scientific Reports, January 2021, Springer Science + Business Media

    Dr. Hsi-Chung Chen

  35. Sex-Specific Moderation Effect of Age on the Associations Between Insomnia Symptoms and Various Psychological Distresses

    Article • Nature and Science of Sleep, January 2021, Taylor & Francis

    Dr. Hsi-Chung Chen

  36. Association of Attention-Deficit/Hyperactivity Disorder and Depression Polygenic Scores with Lithium Response: A Consortium for Lithium Genetics Study

    Article • Complex Psychiatry, January 2021, Karger Publishers

    Dr. Hsi-Chung Chen

  37. Investigation of early and lifetime clinical features and comorbidities for the risk of developing treatment-resistant depression in a 13-year nationwide cohort study

    Article • BMC Psychiatry, November 2020, Springer Science + Business Media

    Dr. Hsi-Chung Chen

  38. Hand grip strength in predicting the risk of osteoporosis in Asian adults

    Article • Journal of Bone and Mineral Metabolism, September 2020, Springer Science + Business Media

    Dr. Hsi-Chung Chen

  39. Validation of Self-Rated Health & Happiness (The Yilan Study)

    Article • Frontiers in Public Health, July 2020, Frontiers

    Dr. Hsi-Chung Chen

  40. Effects of exercise training on sleep quality and heart rate variability in middle-aged and older adults with poor sleep quality: a randomized controlled trial

    Article • Journal of Clinical Sleep Medicine, May 2020, American Academy of Sleep Medicine (AASM)

    Dr. Hsi-Chung Chen

  41. Normative Data of Hand Grip Strength (The Yilan Study)

    Article • Scientific Reports, April 2020, Springer Science + Business Media

    Dr. Hsi-Chung Chen

  42. Hypnotics & Heart Rate Variability (The Yilan Study)

    Article • Sleep Medicine, April 2020, Elsevier

    Dr. Hsi-Chung Chen

  43. Subgrouping Poor Sleep Quality (The Yilan Study)

    Article • Scientific Reports, March 2020, Springer Science + Business Media

    Dr. Hsi-Chung Chen

  44. Association of polygenic score for major depression with response to lithium in patients with bipolar disorder

    Article • Molecular Psychiatry, March 2020, Springer Science + Business Media

    Dr Azmeraw Amare, Dr. Hsi-Chung Chen

  45. Narcolepsy and 2009 H1N1 pandemic vaccination in Taiwan

    Article • Sleep Medicine, February 2020, Elsevier

    Dr. Hsi-Chung Chen

  46. Quantifying the level of difficulty to treat major depressive disorder with antidepressants: Treatment Resistance to Antidepressants Evaluation Scale

    Article • PLoS ONE, January 2020, PLOS

    Dr. Hsi-Chung Chen

  47. The Validity of Inventory of Depressive Symptomatology, Self-report and the Association of Depression with Professional Help-seeking among Individuals with Social Anxiety Disorder

    Article • Taiwanese Journal of Psychiatry, January 2020, Medknow

    Dr. Hsi-Chung Chen

  48. Validation of Brain Health Test-7 for Detecting Patients with Mild Cognitive Impairment and Early Dementia

    Article • Taiwanese Journal of Psychiatry, January 2020, Medknow

    Dr. Hsi-Chung Chen

  49. An examination of the quality and performance of the Alda scale for classifying lithium response phenotypes

    Article • Bipolar Disorders, September 2019, Wiley

    Dr Pierre Alexis Geoffroy, Dr. Hsi-Chung Chen

  50. The association between clinically diagnosed insomnia and age‐related macular degeneration: a population‐based cohort study

    Article • Acta Ophthalmologica, September 2019, Wiley

    Dr. Hsi-Chung Chen

  51. Transcriptome Changes in Relation to Manic Episode

    Article • Frontiers in Psychiatry, May 2019, Frontiers

    Dr. Hsi-Chung Chen

  52. Exploration of microbiota targets for major depressive disorder and mood related traits

    Article • Journal of Psychiatric Research, April 2019, Elsevier

    Dr. Hsi-Chung Chen

  53. The Association Between the Sedative Loads and Clinical Severity Indicators in the First-Onset Major Depressive Disorder

    Article • Frontiers in Psychiatry, March 2019, Frontiers

    Dr. Hsi-Chung Chen

  54. Depression, Anxiety and Sleep-wake disturbance (The Yilan Study)

    Article • Aging & Mental Health, March 2019, Taylor & Francis

    Dr. Hsi-Chung Chen

  55. BMI & Subjective Health Outcomes (The Yilan Study)

    Article • International Journal of Environmental Research and Public Health, November 2018, MDPI AG

    Dr. Hsi-Chung Chen

  56. Narcolepsy and adjuvanted pandemic influenza A (H1N1) 2009 vaccines – Multi-country assessment

    Article • Vaccine, October 2018, Elsevier

    Dr Javier Diez-Domingo, Dr. Hsi-Chung Chen

  57. Analysis of the Influence of microRNAs in Lithium Response in Bipolar Disorder

    Article • Frontiers in Psychiatry, May 2018, Frontiers

    Dr. Hsi-Chung Chen, Janice Fullerton

  58. Muscle Strength & Fall Risk in Older Adults (The Yilan Study)

    Article • BMC Geriatrics, April 2018, Springer Science + Business Media

    Dr. Hsi-Chung Chen

  59. The Association between Earlier Bedtime and Cardiac Vagal Control in Community-Dwelling Older Adults: The Shi-Pai Sleep Study, Taiwan

    Article • Neuropsychiatry, January 2018, OMICS Publishing Group

    Dr. Hsi-Chung Chen

  60. Cortisol awakening response in patients with bipolar disorder during acute episodes and partial remission: A pilot study

    Article • Psychiatry Research, December 2017, Elsevier

    Dr. Hsi-Chung Chen

  61. Evaluation of the interaction between genetic variants of GAD1 and miRNA in bipolar disorders

    Article • Journal of Affective Disorders, December 2017, Elsevier

    Dr. Hsi-Chung Chen

  62. Risk profiles of personality traits for suicidality among mood disorder patients and community controls

    Article • Acta Psychiatrica Scandinavica, November 2017, Wiley

    Dr. Hsi-Chung Chen

  63. Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder

    Article • JAMA Psychiatry, November 2017, American Medical Association (AMA)

    Dr. Hsi-Chung Chen, Janice Fullerton, Dr Azmeraw Amare

  64. Predictors of Change in Self-Reported Sleep Duration in Community-Dwelling Older Adults: The Shih-Pai Sleep Study, Taiwan

    Article • Scientific Reports, July 2017, Springer Science + Business Media

    Dr. Hsi-Chung Chen

  65. Sleep Duration & Cardiac Autonomic Control (The Yilan Study)

    Article • The Journals of Gerontology Series A, March 2017, Oxford University Press (OUP)

    Dr. Hsi-Chung Chen

  66. Comparison of associated features and drug treatment between co-occurring unipolar and bipolar disorders in depressed eating disorder patients

    Article • BMC Psychiatry, February 2017, Springer Science + Business Media

    Dr. Hsi-Chung Chen

  67. Sleep Duration & Hand Grip Strength (The Yilan Study)

    Article • SLEEP, February 2017, Oxford University Press (OUP)

    Dr. Hsi-Chung Chen

  68. Fear of falling and mortality among community-dwelling older adults in the Shih-Pai study in Taiwan: A longitudinal follow-up study

    Article • Geriatrics and Gerontology International, January 2017, Wiley

    Dr. Hsi-Chung Chen

  69. Correlates of self-report chronic insomnia disorders with 1–6 month and 6-month durations in home-dwelling urban older adults - the Shih-Pai Sleep Study in Taiwan: a cross-sectional community study

    Article • BMC Geriatrics, June 2016, Springer Science + Business Media

    Dr. Hsi-Chung Chen

  70. Predictive validity of a five-item symptom checklist to screen psychiatric morbidity and suicide ideation in general population and psychiatric settings

    Article • Journal of the Formosan Medical Association, June 2016, Elsevier

    Dr. Hsi-Chung Chen

  71. Mobile Application–Assisted Cognitive Behavioral Therapy for Insomnia in an Older Adult

    Article • Telemedicine and e-Health, April 2016, Mary Ann Liebert Inc

    Dr. Hsi-Chung Chen

  72. Variables influencing presenting symptoms of patients with eating disorders at psychiatric outpatient clinics

    Article • Psychiatry Research, April 2016, Elsevier

    Dr. Hsi-Chung Chen

  73. Factors Associated with Fear of Falling among Community-Dwelling Older Adults in the Shih-Pai Study in Taiwan

    Article • PLoS ONE, March 2016, PLOS

    Dr. Hsi-Chung Chen

  74. Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study

    Article • The Lancet, March 2016, Elsevier

    Dr. Hsi-Chung Chen, Janice Fullerton

  75. Atrial Fibrillation & Quality of Life (The Yilan Study)

    Article • The Tohoku Journal of Experimental Medicine, January 2016, Tohoku University Medical Press

    Dr. Hsi-Chung Chen

  76. Prevalence and correlates of bipolar disorders in patients with eating disorders

    Article • Journal of Affective Disorders, January 2016, Elsevier

    Dr. Hsi-Chung Chen

  77. The Relationships Among Sleep Quality and Chronotype, Emotional Disturbance, and Insomnia Vulnerability in Shift Nurses

    Article • Journal of Nursing Research, September 2015, Wolters Kluwer Health

    Dr. Hsi-Chung Chen

  78. Gender Difference in the Interaction Effects of Diabetes and Hypertension on Stroke among the Elderly in the Shih-Pai Study, Taiwan

    Article • PLoS ONE, August 2015, PLOS

    Dr. Hsi-Chung Chen

  79. Investigation of Associations between NR1D1, RORA and RORB Genes and Bipolar Disorder

    Article • PLoS ONE, March 2015, PLOS

    Dr. Hsi-Chung Chen

  80. Poor Sleep Quality is Independently Associated with Physical Disability in Older Adults

    Article • Journal of Clinical Sleep Medicine, March 2015, American Academy of Sleep Medicine (AASM)

    Dr. Hsi-Chung Chen

  81. Sex difference in using the SCOFF questionnaire to identify eating disorder patients at a psychiatric outpatient clinic

    Article • Comprehensive Psychiatry, February 2015, Elsevier

    Dr. Hsi-Chung Chen

  82. The Relationship of Sleep Duration with Obesity and Sarcopenia in Community-Dwelling Older Adults

    Article • Gerontology, January 2015, Karger Publishers

    Dr. Hsi-Chung Chen

  83. Anxiety, Depression and Quality of Life in CVD (The Yilan Study)

    Article • PLoS ONE, September 2014, PLOS

    Dr. Hsi-Chung Chen

  84. Leuprolide-Induced Extrapyramidal Symptoms Successfully Treated With Propranolol

    Article • Psychosomatics, March 2014, Elsevier

    Dr. Hsi-Chung Chen

  85. Familiality and clinical outcomes of sleep disturbances in major depressive and bipolar disorders

    Article • Journal of Psychosomatic Research, January 2014, Elsevier

    Dr. Hsi-Chung Chen

  86. The Misdiagnosis of Steroid-Responsive Encephalopathy Associated with Autoimmune Thyroiditis as Masked Depression in an Elderly Euthyroid Woman

    Article • Psychosomatics, November 2013, Elsevier

    Dr. Hsi-Chung Chen

  87. Sertraline alleviated osmophobia caused by partial hypopituitarism with isolated ACTH deficiency

    Article • General Hospital Psychiatry, September 2013, Elsevier

    Dr. Hsi-Chung Chen

  88. Surprising View of Insomnia and Sleeping Pills

    Article • SLEEP, August 2013, Associated Professional Sleep Societies (APSS)

    Dr. Daniel F. Kripke, Dr. Hsi-Chung Chen

  89. A Nine-Year Follow-up Study of Sleep Patterns and Mortality in Community-Dwelling Older Adults in Taiwan

    Article • SLEEP, August 2013, Oxford University Press (OUP)

    Dr. Hsi-Chung Chen

  90. Enhancing Adherence to Cognitive Behavioral Therapy for Insomnia through Machine and Social Persuasion

    Article • August 2013, Institute of Electrical & Electronics Engineers (IEEE)

    Dr. Hsi-Chung Chen

  91. Early neuropsychiatric involvement in antiphospholipid syndrome

    Article • General Hospital Psychiatry, September 2012, Elsevier

    Dr. Hsi-Chung Chen

  92. Exercise training improves sleep quality in middle-aged and older adults with sleep problems: a systematic review

    Article • Journal of Physiotherapy, September 2012, Elsevier

    Dr. Hsi-Chung Chen

  93. Cardiac vagal control and theoretical models of co-occurring depression and anxiety: A cross-sectional psychophysiological study of community elderly

    Article • BMC Psychiatry, July 2012, Springer Science + Business Media

    Dr. Hsi-Chung Chen

  94. Detoxification of high-dose zolpidem using cross-titration with an adequate equivalent dose of diazepam

    Article • General Hospital Psychiatry, March 2012, Elsevier

    Dr. Hsi-Chung Chen

  95. Management of Sleep Disorders: Light Therapy

    Article • January 2012, Springer Science + Business Media

    Dr. Hsi-Chung Chen

  96. Psychotic Disorder Due to Phosphaturic Mesenchymal Tumor with Mixed Connective Tissue Variant

    Article • Psychosomatics, January 2012, Elsevier

    Dr. Hsi-Chung Chen

  97. Recurrent escitalopram-induced hyponatremia in an elderly woman with dementia with Lewy bodies

    Article • General Hospital Psychiatry, January 2012, Elsevier

    Dr. Hsi-Chung Chen

  98. The relationship between pre-sleep arousal and spontaneous arousals from sleep in subjects referred for diagnostic polysomnograms

    Article • Journal of the Chinese Medical Association, February 2011, Wolters Kluwer Health

    Dr. Hsi-Chung Chen

  99. Risk Predictors for Hypnosedative-Related Complex Sleep Behaviors

    Article • The Journal of Clinical Psychiatry, April 2010, Physicians Postgraduate Press, Inc

    Dr. Hsi-Chung Chen

  100. Gender differences in the relationship between depression and cardiac autonomic function among community elderly

    Article • International Journal of Geriatric Psychiatry, March 2010, Wiley

    Dr. Hsi-Chung Chen