All Stories

  1. Single-cell analyses highlight the proinflammatory contribution of C1q-high monocytes to Behçet’s disease

    Article • Proceedings of the National Academy of Sciences, June 2022, Proceedings of the National Academy of Sciences

    Prof. houzao chen

  2. Sirt4 accelerates Ang II-induced pathological cardiac hypertrophy by inhibiting manganese superoxide dismutase activity

    Article • European Heart Journal, April 2016, European Society of Cardiology

    Dr Xiaoqiang Tang, Prof. houzao chen

  3. Epigenetic regulation of NKG2D ligands is involved in exacerbated atherosclerosis development in Sirt6 heterozygous mice

    Article • Scientific Reports, April 2016, Nature

    Dr Xiaoqiang Tang, Prof. houzao chen

  4. Disequilibrium of Blood Coagulation and Fibrinolytic System in Patients With Coronary Artery Ectasia

    Article • Medicine, February 2016, Wolters Kluwer Health

    Prof. houzao chen

  5. NG2 Ablation Reduces Low-Density Lipoprotein Retention of Synthetic Smooth Muscle Cells and Atherogenesis

    Article • Arteriosclerosis Thrombosis and Vascular Biology, November 2015, Wolters Kluwer Health

    Prof. houzao chen

  6. The Four Layers of Aging

    Article • Cell Systems, September 2015, Elsevier

    Prof. houzao chen

  7. Neutrophil serine proteases and their endogenous inhibitors in coronary artery ectasia patients

    Article • Anadolu Kardiyoloji Dergisi/The Anatolian Journal of Cardiology, August 2015, Kare Publishing

    Prof. houzao chen

  8. Sox2 Deacetylation by Sirt1 Is Involved in Mouse Somatic Reprogramming

    Article • Stem Cells, May 2015, Wiley

    Prof. houzao chen

  9. Corrigendum: Interferon regulatory factor 9 is critical for neointima formation following vascular injury

    Article • Nature Communications, April 2015, Nature

    Prof. houzao chen

  10. Suppression of Mic60 compromises mitochondrial transcription and oxidative phosphorylation

    Article • Scientific Reports, January 2015, Nature

    Prof. houzao chen

  11. Extracellular matrix turnover in coronary artery ectasia patients

    Article • Heart and Vessels, January 2015, Springer Science + Business Media

    Prof. houzao chen

  12. Interferon regulatory factor 9 is a key mediator of hepatic ischemia/reperfusion injury

    Article • Journal of Hepatology, January 2015, Elsevier

    Prof. houzao chen

  13. Regulation of Cell Cycle Regulators by SIRT1 Contributes to Resveratrol-Mediated Prevention of Pulmonary Arterial Hypertension

    Article • BioMed Research International, January 2015, Hindawi Publishing Corporation

    Prof. houzao chen

  14. Resveratrol Possesses Protective Effects in a Pristane-Induced Lupus Mouse Model

    Article • PLoS ONE, December 2014, PLOS

    Prof. houzao chen

  15. Overexpression of Mitofilin in the Mouse Heart Promotes Cardiac Hypertrophy in Response to Hypertrophic Stimuli

    Article • Antioxidants & Redox Signaling, October 2014, Mary Ann Liebert Inc

    Prof. houzao chen

  16. Interferon regulatory factor 9 is critical for neointima formation following vascular injury

    Article • Nature Communications, October 2014, Nature

    Prof. houzao chen

  17. GW25-e1524 SIRT1-Mediated Epigenetic Downregulation of Plasminogen Activator Inhibitor-1 Prevents Vascular Endothelial Replicative Senescence

    Article • Journal of the American College of Cardiology, October 2014, Elsevier

    Prof. houzao chen

  18. Overexpression of a dominant-negative mutant of SIRT1 in mouse heart causes cardiomyocyte apoptosis and early-onset heart failure

    Article • Science in China Series C Life Sciences, August 2014, Springer Science + Business Media

    Dr Xiaoqiang Tang, Prof. houzao chen

  19. Mechanistic perspectives of calorie restriction on vascular homeostasis

    Article • Science in China Series C Life Sciences, August 2014, Springer Science + Business Media

    Prof. houzao chen

  20. SIRT 1‐mediated epigenetic downregulation of plasminogen activator inhibitor‐1 prevents vascular endothelial replicative senescence

    Article • Aging Cell, July 2014, Wiley

    Prof. houzao chen

  21. PS200. The Effect of VEGF Activating Transcription Factor in Therapeutic Angiogenesis and Skeletal Muscle Fiber in the Mouse With Hindlimb Ischemia

    Article • Journal of Vascular Surgery, June 2014, Elsevier

    Prof. houzao chen

  22. The Involvement of NFAT Transcriptional Activity Suppression in SIRT1-Mediated Inhibition of COX-2 Expression Induced by PMA/Ionomycin

    Article • PLoS ONE, May 2014, PLOS

    Dr Xiaoqiang Tang, Prof. houzao chen

  23. Mitochondria, endothelial cell function, and vascular diseases

    Article • Frontiers in Physiology, May 2014, Frontiers

    Dr Xiaoqiang Tang, Prof. houzao chen

  24. Overexpression of SIRT1 in vascular smooth muscle cells attenuates angiotensin II-induced vascular remodeling and hypertension in mice

    Article • Journal of Molecular Medicine, December 2013, Springer Science + Business Media

    Prof. houzao chen

  25. Cross-talk between SIRT1 and p66Shc in vascular diseases

    Article • Trends in Cardiovascular Medicine, October 2013, Elsevier

    Prof. houzao chen

  26. Oxidative stress in atrial fibrillation: An emerging role of NADPH oxidase

    Article • Journal of Molecular and Cellular Cardiology, September 2013, Elsevier

    Prof. houzao chen

  27. SIRT1 mediates the protective function of Nkx2.5 during stress in cardiomyocytes

    Article • Basic Research in Cardiology, June 2013, Springer Science + Business Media

    Prof. houzao chen

  28. Systems biomedicine: It’s your turn—Recent progress in systems biomedicine

    Article • Quantitative Biology, June 2013, Springer Science + Business Media

    Prof. houzao chen

  29. Up-regulation of Fas Ligand Expression by Sirtuin 1 in both Flow-restricted Vessels and Serum-stimulated Vascular Smooth Muscle Cells

    Article • Chinese Medical Sciences Journal, June 2013, Elsevier

    Prof. houzao chen

  30. Lysine-specific Demethylase 1 Represses THP-1 Monocyte-to-macrophage Differentiation

    Article • Chinese Medical Sciences Journal, June 2013, Elsevier

    Prof. houzao chen

  31. SIRT1 suppresses PMA and ionomycin-induced ICAM-1 expression in endothelial cells

    Article • Science in China Series C Life Sciences, December 2012, Springer Science + Business Media

    Prof. houzao chen

  32. Mitofilin regulates cytochrome c release during apoptosis by controlling mitochondrial cristae remodeling

    Article • Biochemical and Biophysical Research Communications, November 2012, Elsevier

    Prof. houzao chen

  33. Genetic analysis of the SIRT1 gene promoter in myocardial infarction

    Article • Biochemical and Biophysical Research Communications, September 2012, Elsevier

    Prof. houzao chen

  34. Endothelium-specific SIRT1 overexpression inhibits hyperglycemia-induced upregulation of vascular cell senescence

    Article • Science in China Series C Life Sciences, June 2012, Springer Science + Business Media

    Prof. houzao chen

  35. The Human Paraoxonase Gene Cluster As a Target in the Treatment of Atherosclerosis

    Article • Antioxidants & Redox Signaling, March 2012, Mary Ann Liebert Inc

    Prof. houzao chen

  36. Translational research: Lessons from past research, growing up nowadays, and development goal in future

    Article • Science in China Series C Life Sciences, December 2011, Springer Science + Business Media

    Prof. houzao chen

  37. Sirt1 deacetylates c-Myc and promotes c-Myc/Max association

    Article • The International Journal of Biochemistry & Cell Biology, November 2011, Elsevier

    Prof. houzao chen

  38. Positive regulation of hepatic miR-122 expression by HNF4α

    Article • Journal of Hepatology, September 2011, Elsevier

    Prof. houzao chen

  39. The histone trimethyllysine demethylase JMJD2A promotes cardiac hypertrophy in response to hypertrophic stimuli in mice

    Article • Journal of Clinical Investigation, June 2011, American Society for Clinical Investigation

    Prof. houzao chen

  40. Cardiac-specific overexpression of E3 ligase Nrdp1 increases ischemia and reperfusion-induced cardiac injury

    Article • Basic Research in Cardiology, February 2011, Springer Science + Business Media

    Prof. houzao chen

  41. Regulation of Acyl-coenzyme A:Cholesterol Acyltransferase 2 Expression by Saturated Fatty Acids

    Article • Chinese Medical Sciences Journal, December 2010, Elsevier

    Prof. houzao chen

  42. Involvement of the p65/RelA subunit of NF-κB in TNF-α-induced SIRT1 expression in vascular smooth muscle cells

    Article • Biochemical and Biophysical Research Communications, July 2010, Elsevier

    Prof. houzao chen

  43. A20 attenuates vascular smooth muscle cell proliferation and migration through blocking PI3k/Akt singling in vitro and in vivo

    Article • Journal of Biomedical Science, January 2007, Springer Science + Business Media

    Prof. houzao chen

  44. A20 inhibits oxidized low-density lipoprotein-induced apoptosis through negative Fas/Fas ligand-dependent activation of caspase-8 and mitochondrial pathways in murine RAW264.7 macrophages

    Article • Journal of Cellular Physiology, January 2006, Wiley

    Prof. houzao chen