All Stories

  1. Lighting Up and Identifying Metal-Binding Proteins in Cells

    Article • JACS Au, November 2024, American Chemical Society (ACS)

    Hongzhe Sun

  2. Copper regulates the host innate immune response against bacterial infection via activation of ALPK1 kinase

    Article • Proceedings of the National Academy of Sciences, January 2024, Proceedings of the National Academy of Sciences

    Hongzhe Sun

  3. Clinically used drug arsenic trioxide targets XIAP and overcomes apoptosis resistance in an organoid-based preclinical cancer model

    Article • Chemical Science, January 2024, Royal Society of Chemistry

    Hongzhe Sun

  4. Mechanistic insights into bismuth(iii) inhibition of SARS-CoV-2 helicase

    Article • Chemical Science, January 2024, Royal Society of Chemistry

    Hongzhe Sun

  5. Metal-detection based techniques and their applications in metallobiology

    Article • Chemical Science, January 2024, Royal Society of Chemistry

    Hongzhe Sun

  6. Development of Pan-Anti-SARS-CoV-2 Agents through Allosteric Inhibition of nsp14/nsp10 Complex

    Article • ACS Infectious Diseases, October 2023, American Chemical Society (ACS)

    Hongzhe Sun

  7. SaeR as a novel target for antivirulence therapy against Staphylococcus aureus

    Article • Emerging Microbes & Infections, September 2023, Taylor & Francis

    Hongzhe Sun

  8. Metallo-sideromycin as a dual functional complex for combating antimicrobial resistance

    Article • Nature Communications, September 2023, Springer Science + Business Media

    Hongzhe Sun

  9. Metalloproteomics

    Article • April 2023, Taylor & Francis

    Hongzhe Sun

  10. Mitochondrial ATP synthase as a direct molecular target of chromium(III) to ameliorate hyperglycaemia stress

    Article • Nature Communications, March 2023, Springer Science + Business Media

    Hongzhe Sun

  11. Rapid synthesis of bismuth-organic frameworks as selective antimicrobial materials against microbial biofilms

    Article • Materials Today Bio, February 2023, Elsevier

    Hongzhe Sun

  12. Gold drugs as colistin adjuvants in the fight against MCR-1 producing bacteria

    Article • JBIC Journal of Biological Inorganic Chemistry, January 2023, Springer Science + Business Media

    Hongzhe Sun

  13. A dual covalent binder for labelling and inhibiting serine and metallo-carbapenemases

    Article • Chemical Communications, January 2023, Royal Society of Chemistry

    Hongzhe Sun

  14. Dual-action gallium-flavonoid compounds for combating Pseudomonas aeruginosa infection

    Article • RSC Chemical Biology, January 2023, Royal Society of Chemistry

    Hongzhe Sun

  15. Metallomics and metalloproteomics

    Article • January 2023, Elsevier

    Hongzhe Sun

  16. Metal-coding assisted serological multi-omics profiling deciphers the role of selenium in COVID-19 immunity

    Article • Chemical Science, January 2023, Royal Society of Chemistry

    Hongzhe Sun

  17. Metal Complexes as Resistance Breakers or Metalloantibiotics for Combating Antimicrobial Resistance

    Article • December 2022, Wiley

    Hongzhe Sun

  18. Computed Tomography of Cartilage: An Exploration of Novel Cationic Bismuth Contrast Agent

    Article • Annals of Biomedical Engineering, November 2022, Springer Science + Business Media

    Hongzhe Sun

  19. Binding of ruthenium and osmium at non‑iron sites of transferrin accounts for their iron-independent cellular uptake

    Article • Journal of Inorganic Biochemistry, September 2022, Elsevier

    Hongzhe Sun

  20. An ensemble 3D deep-learning model to predict protein metal-binding site

    Article • Cell Reports Physical Science, September 2022, Elsevier

    Hongzhe Sun

  21. Metalloproteomics for Biomedical Research: Methodology and Applications

    Article • Annual Review of Biochemistry, June 2022, Annual Reviews

    Hongzhe Sun

  22. Re-sensitization of mcr carrying multidrug resistant bacteria to colistin by silver

    Article • Proceedings of the National Academy of Sciences, March 2022, Proceedings of the National Academy of Sciences

    Hongzhe Sun

  23. Regulation of DNA-binding activity of the Staphylococcus aureus catabolite control protein A by copper (II)-mediated oxidation

    Article • Journal of Biological Chemistry, March 2022, Elsevier

    Hongzhe Sun

  24. A hydroxide lock for metallo-β-lactamases

    Article • Nature Chemistry, January 2022, Springer Science + Business Media

    Hongzhe Sun

  25. Orally administered bismuth drug together with N-acetyl cysteine as a broad-spectrum anti-coronavirus cocktail therapy

    Article • Chemical Science, January 2022, Royal Society of Chemistry

    Hongzhe Sun

  26. Multiplex metal-detection based assay (MMDA) for COVID-19 diagnosis and identification of disease severity biomarkers

    Article • Chemical Science, January 2022, Royal Society of Chemistry

    Hongzhe Sun

  27. Metal-based strategies for the fight against COVID-19

    Article • Chemical Communications, January 2022, Royal Society of Chemistry

    Hongzhe Sun

  28. Multiplex Single‐Cell Analysis of Cancer Cells Enables Unbiased Uncovering Subsets Associated with Cancer Relapse: Heterogeneity of Multidrug Resistance in Precursor B‐ALL

    Article • ChemMedChem, November 2021, Wiley

    Hongzhe Sun

  29. Eradication of Porphyromonas gingivalis Persisters Through Colloidal Bismuth Subcitrate Synergistically Combined With Metronidazole

    Article • Frontiers in Microbiology, October 2021, Frontiers

    Hongzhe Sun

  30. Author Correction: Multi-target mode of action of silver against Staphylococcus aureus endows it with capability to combat antibiotic resistance

    Article • Nature Communications, July 2021, Springer Science + Business Media

    Hongzhe Sun

  31. Multi-target mode of action of silver against Staphylococcus aureus endows it with capability to combat antibiotic resistance

    Article • Nature Communications, June 2021, Springer Science + Business Media

    Hongzhe Sun

  32. Clofazimine broadly inhibits coronaviruses including SARS-CoV-2

    Article • Nature, March 2021, Springer Science + Business Media

    Hongzhe Sun

  33. Medicinal chemistry and biomedical applications of bismuth-based compounds and nanoparticles

    Article • Chemical Society Reviews, January 2021, Royal Society of Chemistry

    Hongzhe Sun

  34. A. Sigel, E. Freisinger & R. K. O. Sigel (Eds.), M. E. Sosa Torres & P. M. H. Kroneck (volume Eds.): Transition Metals and Sulfur – A Strong Relationship for Life

    Article • Zeitschrift für Naturforschung C, November 2020, De Gruyter

    Hongzhe Sun

  35. Resensitizing carbapenem- and colistin-resistant bacteria to antibiotics using auranofin

    Article • Nature Communications, October 2020, Springer Science + Business Media

    Hongzhe Sun

  36. Metallodrug ranitidine bismuth citrate suppresses SARS-CoV-2 replication and relieves virus-associated pneumonia in Syrian hamsters

    Article • Nature Microbiology, October 2020, Springer Science + Business Media

    Hongzhe Sun

  37. Metalloproteomics in conjunction with other omics for uncovering the mechanism of action of metallodrugs: Mechanism-driven new therapy development

    Article • Current Opinion in Chemical Biology, April 2020, Elsevier

    Hongzhe Sun

  38. Bismuth—The Magic Element

    Article • Inorganic Chemistry, March 2020, American Chemical Society (ACS)

    Hongzhe Sun

  39. Atomic differentiation of silver binding preference in protein targets:Escherichia colimalate dehydrogenase as a paradigm

    Article • Chemical Science, January 2020, Royal Society of Chemistry

    Hongzhe Sun

  40. Bismuth drugs as antimicrobial agents

    Article • January 2020, Elsevier

    Hongzhe Sun

  41. Predicting disease-associated mutation of metal-binding sites in proteins using a deep learning approach

    Article • Nature Machine Intelligence, December 2019, Springer Science + Business Media

    Hongzhe Sun

  42. Zinc excess increases cellular demand for iron and decreases tolerance to copper in Escherichia coli

    Article • Journal of Biological Chemistry, November 2019, Elsevier

    Hongzhe Sun

  43. Recognition of Proteins by Metal Chelation-Based Fluorescent Probes in Cells

    Article • Frontiers in Chemistry, August 2019, Frontiers

    Hongzhe Sun

  44. Metalloproteomics for Unveiling the Mechanism of Action of Metallodrugs

    Article • Inorganic Chemistry, July 2019, American Chemical Society (ACS)

    Hongzhe Sun

  45. Deciphering molecular mechanism of silver by integrated omic approaches enables enhancing its antimicrobial efficacy in E. coli

    Article • PLoS Biology, June 2019, PLOS

    Hongzhe Sun

  46. Bismuth drugs tackle Porphyromonas gingivalis and attune cytokine response in human cells

    Article • Metallomics, May 2019, Oxford University Press (OUP)

    Hongzhe Sun

  47. The unique trimeric assembly of the virulence factor HtrA from Helicobacter pylori occurs via N-terminal domain swapping

    Article • Journal of Biological Chemistry, May 2019, Elsevier

    Hongzhe Sun

  48. A Novel Synthetic Compound, Bismuth Zinc Citrate, Could Potentially Reduce Cisplatin-Induced Toxicity Without Compromising the Anticancer Effect Through Enhanced Expression of Antioxidant Protein

    Article • Translational Oncology, May 2019, Elsevier

    Hongzhe Sun

  49. Green Fluorescent Probe for Imaging His6-Tagged Proteins Inside Living Cells

    Article • ACS Sensors, April 2019, American Chemical Society (ACS)

    Hongzhe Sun

  50. MetaMarker: a pipeline for de novo discovery of novel metagenomic biomarkers

    Article • Bioinformatics, March 2019, Oxford University Press (OUP)

    Hongzhe Sun

  51. Antimicrobial silver targets glyceraldehyde-3-phosphate dehydrogenase in glycolysis of E. coli

    Article • Chemical Science, January 2019, Royal Society of Chemistry

    Hongzhe Sun

  52. Bismuth: Environmental Pollution and Health Effects

    Article • January 2019, Elsevier

    Hongzhe Sun

  53. Combination of gallium(iii) with acetate for combating antibiotic resistant Pseudomonas aeruginosa

    Article • Chemical Science, January 2019, Royal Society of Chemistry

    Hongzhe Sun

  54. S-Dimethylarsino-glutathione (darinaparsin®) targets histone H3.3, leading to TRAIL-induced apoptosis in leukemia cells

    Article • Chemical Communications, January 2019, Royal Society of Chemistry

    Hongzhe Sun

  55. Systems Approaches for Unveiling the Mechanism of Action of Bismuth Drugs: New Medicinal Applications beyond Helicobacter Pylori Infection

    Article • Accounts of Chemical Research, December 2018, American Chemical Society (ACS)

    Hongzhe Sun

  56. Cell Cycle-Dependent Uptake and Cytotoxicity of Arsenic-Based Drugs in Single Leukemia Cells

    Article • Analytical Chemistry, August 2018, American Chemical Society (ACS)

    Hongzhe Sun

  57. The role of citrate, lactate and transferrin in determining titanium release from surgical devices into human serum

    Article • JBIC Journal of Biological Inorganic Chemistry, April 2018, Springer Science + Business Media

    Hongzhe Sun

  58. Bismuth antimicrobial drugs serve as broad-spectrum metallo-β-lactamase inhibitors

    Article • Nature Communications, January 2018, Springer Science + Business Media

    Dr Pak-Leung Ho, Hongzhe Sun

  59. Metallochaperone UreG serves as a new target for design of urease inhibitor: A novel strategy for development of antimicrobials

    Article • PLoS Biology, January 2018, PLOS

    Hongzhe Sun

  60. Multi-omics and temporal dynamics profiling reveal disruption of central metabolism inHelicobacter pylorion bismuth treatment

    Article • Chemical Science, January 2018, Royal Society of Chemistry

    Hongzhe Sun

  61. Tracking iron-associated proteomes in pathogens by a fluorescence approach

    Article • Metallomics, January 2018, Oxford University Press (OUP)

    Hongzhe Sun

  62. Functional disruption of peroxiredoxin by bismuth antiulcer drugs attenuates Helicobacter pylori survival

    Article • JBIC Journal of Biological Inorganic Chemistry, March 2017, Springer Science + Business Media

    Hongzhe Sun

  63. A Ni-NTA-based red fluorescence probe for protein labelling in live cells

    Article • Journal of Materials Chemistry B, January 2017, Royal Society of Chemistry

    Hongzhe Sun

  64. Cytotoxicity of arsenic trioxide in single leukemia cells by time-resolved ICP-MS together with lanthanide tags

    Article • Chemical Communications, January 2017, Royal Society of Chemistry

    Hongzhe Sun

  65. Identification of catabolite control protein A fromStaphylococcus aureusas a target of silver ions

    Article • Chemical Science, January 2017, Royal Society of Chemistry

    Hongzhe Sun

  66. Integration of fluorescence imaging with proteomics enables visualization and identification of metallo-proteomes in living cells

    Article • Metallomics, January 2017, Oxford University Press (OUP)

    Hongzhe Sun

  67. Integrative approach for the analysis of the proteome-wide response to bismuth drugs in Helicobacter pylori

    Article • Chemical Science, January 2017, Royal Society of Chemistry

    Hongzhe Sun

  68. Exploration into the nickel ‘microcosmos’ in prokaryotes

    Article • Coordination Chemistry Reviews, March 2016, Elsevier

    Hongzhe Sun

  69. UreE-UreG Complex Facilitates Nickel Transfer and Preactivates GTPase of UreG in Helicobacter pylori

    Article • Journal of Biological Chemistry, May 2015, Elsevier

    Hongzhe Sun

  70. Glutathione and multidrug resistance protein transporter mediate a self-propelled disposal of bismuth in human cells

    Article • Proceedings of the National Academy of Sciences, March 2015, Proceedings of the National Academy of Sciences

    Hongzhe Sun

  71. Rapid labeling of intracellular His-tagged proteins in living cells

    Article • Proceedings of the National Academy of Sciences, February 2015, Proceedings of the National Academy of Sciences

    Hongzhe Sun

  72. Loss of APD1 in Yeast Confers Hydroxyurea Sensitivity Suppressed by Yap1p Transcription Factor

    Article • Scientific Reports, January 2015, Nature

    Dr Chi-Ming Wong, Hongzhe Sun

  73. Metallomic and metalloproteomic strategies in elucidating the molecular mechanisms of metallodrugs

    Article • Dalton Transactions, January 2015, Royal Society of Chemistry

    Hongzhe Sun

  74. “Anion clamp” allows flexible protein to impose coordination geometry on metal ions

    Article • Chemical Communications, January 2015, Royal Society of Chemistry

    Hongzhe Sun

  75. On-line coupling of continuous-flow gel electrophoresis with inductively coupled plasma-mass spectrometry to quantitatively evaluate intracellular metal binding properties of metallochaperones HpHypA and HpHspA in E. coli cells

    Article • Metallomics, January 2015, Oxford University Press (OUP)

    Hongzhe Sun

  76. Bio-coordination of bismuth in Helicobacter pylori revealed by immobilized metal affinity chromatography

    Article • Chemical Communications, January 2015, Royal Society of Chemistry

    Hongzhe Sun

  77. Selective interaction of Hpn-like protein with nickel, zinc and bismuth in vitro and in cells by FRET

    Article • Journal of Inorganic Biochemistry, January 2015, Elsevier

    Hongzhe Sun

  78. Antimony and Bismuth

    Article • July 2014, Royal Society of Chemistry

    Hongzhe Sun

  79. Structure of RPA32 bound to the N‐terminus of SMARCAL1 redefines the binding interface between RPA32 and its interacting proteins

    Article • European Journal of Biochemistry, July 2014, Wiley

    Hongzhe Sun

  80. Urease inactivation by an unusual GroES chaperonin

    Article • Science China Chemistry, February 2014, Springer Science + Business Media

    Hongzhe Sun

  81. Functional disruption of HypB, a GTPase of Helicobacter pylori, by bismuth

    Article • Chemical Communications, January 2014, Royal Society of Chemistry

    Hongzhe Sun

  82. In-cell NMR: an emerging approach for monitoring metal-related events in living cells

    Article • Metallomics, January 2014, Oxford University Press (OUP)

    Hongzhe Sun, Dr Hongyan Li

  83. Size-tunable fabrication of multifunctional Bi2O3 porous nanospheres for photocatalysis, bacteria inactivation and template-synthesis

    Article • Nanoscale, January 2014, Royal Society of Chemistry

    Hongzhe Sun, Hao Yang, Professor juncheng Hu

  84. Nickel translocation between metallochaperones HypA and UreE in Helicobacter pylori

    Article • Metallomics, January 2014, Oxford University Press (OUP)

    Hongzhe Sun

  85. BiOX (X=Cl, Br, I) nanostructures: Mannitol-mediated microwave synthesis, visible light photocatalytic performance, and Cr(VI) removal capacity

    Article • Journal of Colloid and Interface Science, November 2013, Elsevier

    Hongzhe Sun

  86. Identification of Metal‐Associated Proteins in Cells by Using Continuous‐Flow Gel Electrophoresis and Inductively Coupled Plasma Mass Spectrometry

    Article • Angewandte Chemie, April 2013, Wiley

    Hongzhe Sun

  87. ChemInform Abstract: Template‐Free Fabrication of Bi2O3 and (BiO)2CO3 Nanotubes and Their Application in Water Treatment.

    Article • ChemInform, March 2013, Wiley

    Hongzhe Sun

  88. Tunable BiOCl hierarchical nanostructures for high-efficient photocatalysis under visible light irradiation

    Article • Chemical Engineering Journal, March 2013, Elsevier

    Hongzhe Sun

  89. Kinetics and thermodynamics of metal binding to the N-terminus of a human copper transporter, hCTR1

    Article • Chemical Communications, January 2013, Royal Society of Chemistry

    Hongzhe Sun

  90. Binding of oxo-Cu2 clusters to ferric ion-binding protein A from Neisseria gonorrhoeae: a structural insight

    Article • Metallomics, January 2013, Oxford University Press (OUP)

    Hongzhe Sun

  91. Histidine-rich proteins in prokaryotes: metal homeostasis and environmental habitat-related occurrence

    Article • Metallomics, January 2013, Oxford University Press (OUP)

    Hongzhe Sun

  92. Interaction of SlyD with HypB of Helicobacter pylori facilitates nickel trafficking

    Article • Metallomics, January 2013, Oxford University Press (OUP)

    Hongzhe Sun

  93. Structure-oriented bioinformatic approach exploring histidine-rich clusters in proteins

    Article • Metallomics, January 2013, Oxford University Press (OUP)

    Hongzhe Sun

  94. Iron and bismuth bound human serum transferrin reveals a partially-opened conformation in the N-lobe

    Article • Scientific Reports, December 2012, Springer Science + Business Media

    Hongzhe Sun

  95. Template‐Free Fabrication of Bi2O3 and (BiO)2CO3 Nanotubes and Their Application in Water Treatment

    Article • Chemistry - A European Journal, October 2012, Wiley

    Hongzhe Sun

  96. Metallomics in environmental and health related research: Current status and perspectives

    Article • Chinese Science Bulletin, September 2012, Springer Science + Business Media

    Hongzhe Sun

  97. Facile Microwave Synthesis of 3D Flowerlike BiOBr Nanostructures and Their Excellent CrVI Removal Capacity

    Article • European Journal of Inorganic Chemistry, April 2012, Wiley

    Hongzhe Sun, Hao Yang

  98. Recent advances in bioinorganic chemistry of bismuth

    Article • Current Opinion in Chemical Biology, April 2012, Elsevier

    Hongzhe Sun

  99. Folic acid conjugated mPEG-PEI600 as an efficient non-viral vector for targeted nucleic acid delivery

    Article • International Journal of Pharmaceutics, April 2012, Elsevier

    Hongzhe Sun

  100. Covalently linking the Escherichia coli global anaerobic regulator FNR in tandem allows it to function as an oxygen stable dimer

    Article • Biochemical and Biophysical Research Communications, March 2012, Elsevier

    Hongzhe Sun, Aixin Yan

  101. Metallo-GTPase HypB from Helicobacter pylori and Its Interaction with Nickel Chaperone Protein HypA

    Article • Journal of Biological Chemistry, February 2012, Elsevier

    Prof. Kam Bo Wong, Hongzhe Sun

  102. Large-scale synthesis of bismuth hollow nanospheres for highly efficient Cr(vi) removal

    Article • Dalton Transactions, January 2012, Royal Society of Chemistry

    Hongzhe Sun

  103. Activation of carboplatin and nedaplatin by the N-terminus of human copper transporter 1 (hCTR1)

    Article • Chemical Science, January 2012, Royal Society of Chemistry

    Hongzhe Sun

  104. Comparison between copper and cisplatin transport mediated by human copper transporter 1 (hCTR1)

    Article • Metallomics, January 2012, Oxford University Press (OUP)

    Hongzhe Sun

  105. Probing of bismuth antiulcer drug targets in H. pylori by laser ablation-inductively coupled plasma mass spectrometry

    Article • Metallomics, January 2012, Oxford University Press (OUP)

    Hongzhe Sun

  106. Multifaceted SlyD from Helicobacter pylori: implication in [NiFe] hydrogenase maturation

    Article • JBIC Journal of Biological Inorganic Chemistry, November 2011, Springer Science + Business Media

    Hongzhe Sun

  107. Microwave synthesis of BiPO4 nanostructures and their morphology-dependent photocatalytic performances

    Article • Journal of Colloid and Interface Science, November 2011, Elsevier

    Hongzhe Sun

  108. Assembly of Preactivation Complex for Urease Maturation inHelicobacter pylori

    Article • Journal of Biological Chemistry, October 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr. Yu Wai Chen, Prof. Kam Bo Wong, Hongzhe Sun

  109. Histidine-rich protein Hpn from Helicobacter pylori forms amyloid-like fibrils in vitro and inhibits the proliferation of gastric epithelial AGS cells

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, August 2011, Elsevier

    Hongzhe Sun

  110. Tracking Bismuth Antiulcer Drug Uptake in Single Helicobacter pylori Cells

    Article • Journal of the American Chemical Society, April 2011, American Chemical Society (ACS)

    Hongzhe Sun

  111. Metal‐Binding Properties of an Hpn‐Like Histidine‐Rich Protein

    Article • Chemistry - A European Journal, April 2011, Wiley

    Hongzhe Sun

  112. The Effect of the Extracellular Domain of Human Copper Transporter (hCTR1) on Cisplatin Activation

    Article • Angewandte Chemie, February 2011, Wiley

    Hongzhe Sun

  113. The Effect of the Extracellular Domain of Human Copper Transporter (hCTR1) on Cisplatin Activation

    Article • Angewandte Chemie, February 2011, Wiley

    Hongzhe Sun

  114. NMR Studies of Metalloproteins

    Article • January 2011, Springer Science + Business Media

    Hongzhe Sun

  115. Biological Chemistry of Arsenic, Antimony and Bismuth

    Article • November 2010, Wiley

    Hongzhe Sun

  116. Biological Chemistry of Antimony and Bismuth

    Article • November 2010, Wiley

    Hongzhe Sun

  117. Metalloproteomics of Arsenic, Antimony and Bismuth Based Drugs

    Article • November 2010, Wiley

    Hongzhe Sun

  118. Polymeric architectures of bismuth citrate based on dimeric building blocks

    Article • Science China Chemistry, October 2010, Springer Science + Business Media

    Hongzhe Sun

  119. Online coupling of reverse-phase and hydrophilic interaction liquid chromatography for protein and glycoprotein characterization

    Article • Fresenius Journal of Analytical Chemistry, July 2010, Springer Science + Business Media

    Hongzhe Sun

  120. Iron-containing lipoprotein SiaA in SiaABC, the primary heme transporter of Streptococcus pyogenes

    Article • JBIC Journal of Biological Inorganic Chemistry, July 2010, Springer Science + Business Media

    Hongzhe Sun

  121. Nuclear-based Metallomics in Metal-based Drugs

    Article • June 2010, Royal Society of Chemistry

    Hongzhe Sun

  122. Bismuth subcarbonate nanoparticles fabricated by water-in-oil microemulsion-assisted hydrothermal process exhibit anti-Helicobacter pylori properties

    Article • Materials Research Bulletin, May 2010, Elsevier

    Hongzhe Sun

  123. A new capillary electrophoresis buffer for determining organic and inorganic anions in electroplating bath with surfactant additives

    Article • Journal of Chromatography A, May 2010, Elsevier

    Hongzhe Sun

  124. A zinc-binding site by negative selection induces metallodrug susceptibility in an essential chaperonin

    Article • Proceedings of the National Academy of Sciences, March 2010, Proceedings of the National Academy of Sciences

    Hongzhe Sun

  125. A biomimetic zinc activated ion channel

    Article • Chemical Communications, January 2010, Royal Society of Chemistry

    Hongzhe Sun

  126. Metallomics: An integrated science for metals in biology and medicine

    Article • "Annual Reports Section ""A"" (Inorganic Chemistry)", January 2010, Royal Society of Chemistry

    Hongzhe Sun

  127. Metallomics: An integrated biometal science

    Article • Science in China Series B Chemistry, December 2009, Springer Science + Business Media

    Hongzhe Sun

  128. Reactivity of platinum-based antitumor drugs towards a Met- and His-rich 20mer peptide corresponding to the N-terminal domain of human copper transporter 1

    Article • JBIC Journal of Biological Inorganic Chemistry, August 2009, Springer Science + Business Media

    Hongzhe Sun

  129. Effect of cyclodextrin dimers with bipyridyl and biphenyl linking groups on carboxyl ester hydrolysis catalyzed by zinc complex

    Article • Journal of Molecular Catalysis A Chemical, August 2009, Elsevier

    Hongzhe Sun

  130. Structure of a Nickel Chaperone, HypA, from Helicobacter pylori Reveals Two Distinct Metal Binding Sites

    Article • Journal of the American Chemical Society, July 2009, American Chemical Society (ACS)

    Hongzhe Sun, Dr Kong Hung SZE

  131. Iron depletion decreases proliferation and induces apoptosis in a human colonic adenocarcinoma cell line, Caco2

    Article • Journal of Inorganic Biochemistry, July 2009, Elsevier

    Hongzhe Sun

  132. The structural and biological significance of the EAAEAE insert in the α-domain of human neuronal growth inhibitory factor

    Article • European Journal of Biochemistry, June 2009, Wiley

    Hongzhe Sun

  133. Crystal Structure and Metal Binding Properties of the Lipoprotein MtsA, Responsible for Iron Transport in Streptococcus pyogenes

    Article • Biochemistry, June 2009, American Chemical Society (ACS)

    Hongzhe Sun

  134. Phosphodiester hydrolysis and specific DNA binding and cleavage promoted by guanidinium-functionalized zinc complexes

    Article • Journal of Inorganic Biochemistry, May 2009, Elsevier

    Hongzhe Sun

  135. Important roles of the conserved linker-KKS in human neuronal growth inhibitory factor

    Article • BioMetals, March 2009, Springer Science + Business Media

    Hongzhe Sun

  136. Identification and characterization of metallodrug binding proteins by (metallo)proteomics

    Article • Metallomics, January 2009, Oxford University Press (OUP)

    Hongzhe Sun

  137. Editorial and Advisory Board profiles

    Article • Metallomics, January 2009, Oxford University Press (OUP)

    Hongzhe Sun

  138. Identification of Proteins Related to Nickel Homeostasis in Helicobater pylori by Immobilized Metal Affinity Chromatography and Two-Dimensional Gel Electrophoresis

    Article • Metal-Based Drugs, December 2008, Hindawi Publishing Corporation

    Hongzhe Sun

  139. Study on structure–property–reactivity–function relationship of human neuronal growth inhibitory factor (hGIF)

    Article • Journal of Inorganic Biochemistry, November 2008, Elsevier

    Hongzhe Sun

  140. Binding of Ni2+ to a histidine- and glutamine-rich protein, Hpn-like

    Article • JBIC Journal of Biological Inorganic Chemistry, June 2008, Springer Science + Business Media

    Hongzhe Sun

  141. Structure, topology and assembly of a 32-mer peptide corresponding to the loop 3 and transmembrane domain 4 of divalent metal transporter (DMT1) in membrane-mimetic environments

    Article • Journal of Inorganic Biochemistry, May 2008, Elsevier

    Hongzhe Sun

  142. A Histidine-rich and Cysteine-rich Metal-binding Domain at the C Terminus of Heat Shock Protein A from Helicobacter pylori

    Article • Journal of Biological Chemistry, May 2008, Elsevier

    Hongzhe Sun

  143. Lipoprotein MtsA of MtsABC in Streptococcus pyogenes primarily binds ferrous ion with bicarbonate as a synergistic anion

    Article • FEBS Letters, March 2008, Wiley

    Hongzhe Sun

  144. Double-strand DNA cleavage by copper complexes of 2,2′-dipyridyl with guanidinium/ammonium pendants

    Article • Dalton Transactions, January 2008, Royal Society of Chemistry

    Hongzhe Sun

  145. The effect of nitric oxide on metal release from metallothionein-3: gradual unfolding of the protein

    Article • JBIC Journal of Biological Inorganic Chemistry, December 2007, Springer Science + Business Media

    Hongzhe Sun

  146. Biocoordination chemistry of bismuth: Recent advances

    Article • Coordination Chemistry Reviews, September 2007, Elsevier

    Hongzhe Sun

  147. Effect of α-domain substitution on the structure, property and function of human neuronal growth inhibitory factor

    Article • JBIC Journal of Biological Inorganic Chemistry, August 2007, Springer Science + Business Media

    Hongzhe Sun

  148. Bismuth Complexes Inhibit the SARS Coronavirus

    Article • Angewandte Chemie, August 2007, Wiley

    Hongzhe Sun

  149. Bismuth Complexes Inhibit the SARS Coronavirus

    Article • Angewandte Chemie, August 2007, Wiley

    Hongzhe Sun

  150. Bioinorganic Chemistry of Bismuth and Antimony: Target Sites of Metallodrugs

    Article • ChemInform, June 2007, Wiley

    Hongzhe Sun

  151. A proteomic approach for the identification of bismuth-binding proteins in Helicobacter pylori

    Article • JBIC Journal of Biological Inorganic Chemistry, May 2007, Springer Science + Business Media

    Hongzhe Sun

  152. Solution structures, dynamics, and lipid‐binding of the sterile α‐motif domain of the deleted in liver cancer 2

    Article • Proteins Structure Function and Bioinformatics, May 2007, Wiley

    Hongzhe Sun, Dr Kong Hung SZE

  153. Structural prediction of the β-domain of metallothionein-3 by molecular dynamics simulation

    Article • Proteins Structure Function and Bioinformatics, April 2007, Wiley

    Hongzhe Sun

  154. Metallodrugs

    Article • March 2007, Wiley

    Hongzhe Sun

  155. An Effective Metallohydrolase Model with a Supramolecular Environment: Structures, Properties, and Activities

    Article • Chemistry - A European Journal, March 2007, Wiley

    Hongzhe Sun

  156. Bioinorganic Chemistry of Bismuth and Antimony:  Target Sites of Metallodrugs

    Article • Accounts of Chemical Research, March 2007, American Chemical Society (ACS)

    Hongzhe Sun

  157. Silver nanoparticles: partial oxidation and antibacterial activities

    Article • JBIC Journal of Biological Inorganic Chemistry, February 2007, Springer Science + Business Media

    Hongzhe Sun

  158. Synthesis, Structure, and Activity of Supramolecular Mimics for the Active Site and Arg141 Residue of Copper, Zinc−Superoxide Dismutase

    Article • Inorganic Chemistry, January 2007, American Chemical Society (ACS)

    Hongzhe Sun

  159. Encapsulation of platinum anticancer drugs by apoferritin

    Article • Chemical Communications, January 2007, Royal Society of Chemistry

    Hongzhe Sun, Prof. Xiaoyong Wang

  160. Inhibition of SARS coronavirus helicase by bismuth complexes

    Article • Chemical Communications, January 2007, Royal Society of Chemistry

    Hongzhe Sun

  161. Cleavage of double-strand DNA by zinc complexes of dicationic 2,2′-dipyridyl derivatives

    Article • Dalton Transactions, January 2007, Royal Society of Chemistry

    Hongzhe Sun

  162. Flavonoid Dimers as Bivalent Modulators for Pentamidine and Sodium Stiboglucanate Resistance in Leishmania

    Article • Antimicrobial Agents and Chemotherapy, December 2006, ASM Journals

    Hongzhe Sun

  163. Inhibition of urease by bismuth(III): Implications for the mechanism of action of bismuth drugs

    Article • BioMetals, October 2006, Springer Science + Business Media

    Hongzhe Sun, Robert Hausinger

  164. Mutation at Glu23 eliminates the neuron growth inhibitory activity of human metallothionein-3

    Article • Biochemical and Biophysical Research Communications, October 2006, Elsevier

    Hongzhe Sun

  165. Thermodynamic and Kinetic Aspects of Metal Binding to the Histidine-rich Protein, Hpn

    Article • Journal of the American Chemical Society, August 2006, American Chemical Society (ACS)

    Hongzhe Sun

  166. The role of Thr5 in human neuron growth inhibitory factor

    Article • JBIC Journal of Biological Inorganic Chemistry, April 2006, Springer Science + Business Media

    Hongzhe Sun

  167. Proteomic Analysis of the Mode of Antibacterial Action of Silver Nanoparticles

    Article • Journal of Proteome Research, March 2006, American Chemical Society (ACS)

    Hongzhe Sun

  168. Solution structure and dynamics of human metallothionein‐3 (MT‐3)

    Article • FEBS Letters, January 2006, Wiley

    Hongzhe Sun, Dr Kong Hung SZE

  169. HFIP‐induced structures and assemblies of the peptides from the transmembrane domain 4 of membrane protein Nramp1

    Article • Biopolymers, January 2006, Wiley

    Hongzhe Sun

  170. Fabrication of bismuth subcarbonate nanotube arrays from bismuth citrate

    Article • Chemical Communications, January 2006, Royal Society of Chemistry

    Hongzhe Sun

  171. Expression and characterization of a histidine-rich protein, Hpn: potential for Ni 2+ storage in Helicobacter pylori

    Article • Biochemical Journal, January 2006, Portland Press Ltd.

    Hongzhe Sun

  172. Complexation of antimony (SbV) with guanosine 5′-monophosphate and guanosine 5′-diphospho-d-mannose: Formation of both mono- and bis-adducts

    Article • Journal of Inorganic Biochemistry, December 2005, Elsevier

    Hongzhe Sun

  173. An Insight of S-Nitrosylation of Human GIF

    Article • Chinese Journal of Chemistry, November 2005, Wiley

    Hongzhe Sun

  174. The Stepwise Process of Chromium-Induced DNA Breakage:  Characterization by Electrochemistry, Atomic Force Microscopy, and DNA Electrophoresis

    Article • Chemical Research in Toxicology, September 2005, American Chemical Society (ACS)

    Hongzhe Sun

  175. Transferrin-Mediated Gold Nanoparticle Cellular Uptake

    Article • Bioconjugate Chemistry, April 2005, American Chemical Society (ACS)

    Hongzhe Sun

  176. 51 Sb Antimony in Medicine

    Article • March 2005, Wiley

    Hongzhe Sun

  177. NMR structures and orientation of the fourth transmembrane domain of the rat divalent metal transporter (DMT1) with G185D mutation in SDS micelles

    Article • Biopolymers, January 2005, Wiley

    Hongzhe Sun

  178. Structure, Assembly, and Topology of the G185R Mutant of the Fourth Transmembrane Domain of Divalent Metal Transporter

    Article • Journal of the American Chemical Society, January 2005, American Chemical Society (ACS)

    Hongzhe Sun

  179. Controlled synthesis of high crystalline bismuth sulfide nanorods: using bismuth citrate as a precursor

    Article • Journal of Materials Chemistry, January 2005, Royal Society of Chemistry

    Hongzhe Sun

  180. In Vitro Inhibition of Human Immunodeficiency Virus Type‐1 (HIV‐1) Reverse Transcriptase by Gold(III) Porphyrins

    Article • ChemBioChem, September 2004, Wiley

    Hongzhe Sun

  181. Dynamic and Kinetic Aspects of Metallodrugs by NMR

    Article • August 2004, Wiley

    Hongzhe Sun

  182. The low pKa value of iron‐binding ligand Tyr188 and its implication in iron release and anion binding of human transferrin

    Article • FEBS Letters, August 2004, Wiley

    Hongzhe Sun

  183. Inhibition of alcohol dehydrogenase by bismuth☆

    Article • Journal of Inorganic Biochemistry, August 2004, Elsevier

    Hongzhe Sun

  184. Structure and topology of the transmembrane domain 4 of the divalent metal transporter in membrane‐mimetic environments

    Article • European Journal of Biochemistry, April 2004, Wiley

    Hongzhe Sun

  185. Bismuth in Medicine

    Article • March 2004, Taylor & Francis

    Hongzhe Sun

  186. DNA hydrolysis promoted by di- and multi-nuclear metal complexes

    Article • Coordination Chemistry Reviews, January 2004, Elsevier

    Hongzhe Sun

  187. The effect of the EAAEAE insert on the property of human metallothionein-3

    Article • Protein Engineering Design and Selection, December 2003, Oxford University Press (OUP)

    Hongzhe Sun

  188. Structure of Colloidal Bismuth Subcitrate (CBS) in Dilute HCl:  Unique Assembly of Bismuth Citrate Dinuclear Units ([Bi(cit)2Bi]2-)

    Article • Journal of the American Chemical Society, September 2003, American Chemical Society (ACS)

    Hongzhe Sun

  189. Recognition of antimony and bismuth by peptides and proteins: insight into the mechanism of action

    Article • Journal of Inorganic Biochemistry, July 2003, Elsevier

    Hongzhe Sun

  190. Three dimensional structures and topology of the transmembrane domain 4 of divalent metal transporter (DMT1) in membrane-mimetic environments

    Article • Journal of Inorganic Biochemistry, July 2003, Elsevier

    Hongzhe Sun

  191. Reduction of pentavalent antimony by trypanothione and formation of a binary and ternary complex of antimony(III) and trypanothione

    Article • JBIC Journal of Biological Inorganic Chemistry, June 2003, Springer Science + Business Media

    Hongzhe Sun

  192. Membrane-inserted conformation of transmembrane domain 4 of divalent-metal transporter

    Article • Biochemical Journal, June 2003, Portland Press Ltd.

    Hongzhe Sun

  193. Binding of bismuth to serum proteins: implication for targets of Bi(III) in blood plasma

    Article • Journal of Inorganic Biochemistry, February 2003, Elsevier

    Hongzhe Sun

  194. Gold(iii) porphyrins as a new class of anticancer drugs: cytotoxicity, DNA binding and induction of apoptosis in human cervix epitheloid cancer cellsElectronic supplementary information (ESI) available: Further experimental and crystallographic details...

    Article • Chemical Communications, January 2003, Royal Society of Chemistry

    Hongzhe Sun

  195. An oscillating C22? unit inside a copper rectangleElectronic supplementary information (ESI) available: NMR spectra and computational details. See http://www.rsc.org/suppdata/cc/b3/b301842c/

    Article • Chemical Communications, January 2003, Royal Society of Chemistry

    Hongzhe Sun

  196. Helicases as antiviral drug targets

    Article • Drug News & Perspectives, January 2003, Portico

    Hongzhe Sun

  197. Rapid reduction of pentavalent antimony by trypanothione: potential relevance to antimonial activationElectronic supplementary information (ESI) available: experimental details. See http://www.rsc.org/suppdata/cc/b2/b210240d/

    Article • Chemical Communications, December 2002, Royal Society of Chemistry

    Hongzhe Sun

  198. Complexation of ytterbium to human transferrin and its uptake by K562 cells

    Article • European Journal of Biochemistry, December 2002, Wiley

    Hongzhe Sun

  199. Targeted Drug Delivery via the Transferrin Receptor-Mediated Endocytosis Pathway

    Article • Pharmacological Reviews, December 2002, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Hongzhe Sun

  200. Stereo- and Enantioselective Alkene Epoxidations: A Comparative Study of D4- and D2-Symmetric Homochiral trans-Dioxoruthenium(VI) Porphyrins

    Article • Chemistry - A European Journal, June 2002, Wiley

    Hongzhe Sun

  201. The role of the transferrin–transferrin-receptor system in drug delivery and targeting

    Article • Trends in Pharmacological Sciences, May 2002, Elsevier

    Hongzhe Sun

  202. Interactions of Bismuth with Human Lactoferrin and Recognition of the BiIII−Lactoferrin Complex by Intestinal Cells

    Article • Biochemistry, October 2001, American Chemical Society (ACS)

    Hongzhe Sun

  203. Competitive Binding of Bismuth to Transferrin and Albumin in Aqueous Solution and in Blood Plasma

    Article • Journal of Biological Chemistry, March 2001, Elsevier

    Hongzhe Sun

  204. Intracellular Sb-trypanothione

    Article • Angewandte Chemie, December 2000, Wiley

    Hongzhe Sun

  205. Complexation of Antimony(III) by Trypanothione

    Article • Angewandte Chemie, December 2000, Wiley

    Hongzhe Sun

  206. Interaction of antimony tartrate with the tripeptide glutathione

    Article • European Journal of Biochemistry, September 2000, Wiley

    Hongzhe Sun

  207. TiIV Uptake and Release by Human Serum Transferrin and Recognition of TiIV-Transferrin by Cancer Cells:  Understanding the Mechanism of Action of the Anticancer Drug Titanocene Dichloride

    Article • Biochemistry, July 2000, American Chemical Society (ACS)

    Hongzhe Sun

  208. Stereoselective Formation of Seven-Coordinate Titanium(IV) Monomer and Dimer Complexes of Ethylenebis(o-hydroxyphenyl)glycine

    Article • Inorganic Chemistry, December 1999, American Chemical Society (ACS)

    Hongzhe Sun

  209. ChemInform Abstract: Transferrin as a Metal Ion Mediator

    Article • ChemInform, November 1999, Wiley

    Hongzhe Sun

  210. Interactions of Bismuth Complexes with Metallothionein(II)

    Article • Journal of Biological Chemistry, October 1999, Elsevier

    Hongzhe Sun

  211. Transferrin as a Metal Ion Mediator

    Article • Chemical Reviews, August 1999, American Chemical Society (ACS)

    Hongzhe Sun

  212. Coordination chemistry of metals in medicine: target sites for bismuth

    Article • Coordination Chemistry Reviews, May 1999, Elsevier

    Hongzhe Sun

  213. Bismuth Antiulcer Complexes

    Article • January 1999, Springer Science + Business Media

    Hongzhe Sun

  214. N-lobe versus C-lobe complexation of bismuth by human transferrin

    Article • Biochemical Journal, January 1999, Portland Press Ltd.

    Hongzhe Sun

  215. Coordination of Zn2+ (and Cd2+) by Prokaryotic Metallothionein

    Article • Journal of Biological Chemistry, September 1998, Elsevier

    Hongzhe Sun

  216. The First Specific TiIV-Protein Complex: Potential Relevance to Anticancer Activity of Titanocenes

    Article • Angewandte Chemie, June 1998, Wiley

    Hongzhe Sun

  217. [1H,13C] NMR determination of the order of lobe loading of human transferrin with iron: comparison with other metal ions

    Article • FEBS Letters, February 1998, Wiley

    Hongzhe Sun

  218. New approach to the solution chemistry of bismuth citrate antiulcer complexes

    Article • Chemical Communications, January 1998, Royal Society of Chemistry

    Hongzhe Sun

  219. The Biological and Medicinal Chemistry of Bismuth

    Article • Chemische Berichte, June 1997, Wiley

    Hongzhe Sun

  220. Determination of Bismuth in Serum Urine by Direct Injection Nebulization Inductively Coupled Plasma Mass Spectrometry

    Article • Journal of Analytical Atomic Spectrometry, January 1997, Royal Society of Chemistry

    Hongzhe Sun

  221. Rationalisation of metal binding to transferrin: Prediction of metal-protein stability constants

    Article • January 1997, Springer Science + Business Media

    Hongzhe Sun

  222. Rationalization of the Strength of Metal Binding to Human Serum Transferrin

    Article • European Journal of Biochemistry, December 1996, Wiley

    Hongzhe Sun

  223. Molecular assemblies of diazafluorenone Schiff-base amphiphiles. III.13C NMR investigations of reversed micelles in deuteriochloroform

    Article • Molecular Engineering, September 1996, Springer Science + Business Media

    Hongzhe Sun

  224. Bismuth(III) Complexes of the Tripeptide Glutathione (γ‐L‐Glu–L‐Cys–Gly)

    Article • Chemistry - A European Journal, June 1996, Wiley

    Hongzhe Sun

  225. Solid-state carbon-13 nuclear magnetic resonance investigations of bismuth citrate complexes and crystal structure of Na2[Bi2(cit)2]·7H2O

    Article • Journal of the Chemical Society Dalton Transactions, January 1996, Royal Society of Chemistry

    Hongzhe Sun

  226. 1H NMR Studies of the Imidazole Complex of Cytochrome c: Resonance Assignment and Structural Characterization of the Heme Cavity

    Article • Inorganic Chemistry, February 1995, American Chemical Society (ACS)

    Hongzhe Sun

  227. Ranitidine bismuth(III) citrate

    Article • Journal of the Chemical Society Dalton Transactions, January 1995, Royal Society of Chemistry

    Hongzhe Sun

  228. NMR Investigation of the Aggregation Behavior of Diazafluorenone Schiff Base Amphiphile in CDCL3Solution

    Article • Spectroscopy Letters, November 1993, Taylor & Francis

    Hongzhe Sun

  229. Assignments of Nonexchangeable Proton Resonances and the Solution Structures of d–TGGGT

    Article • Spectroscopy Letters, September 1993, Taylor & Francis

    Hongzhe Sun

  230. Syntheses and Characterization of Coenzyme B12 Analogues Containing 2′-Deoxynucleosede

    Article • Synthesis and Reactivity in Inorganic Metal-Organic and Nano-Metal Chemistry, March 1993, Taylor & Francis

    Hongzhe Sun

  231. Two Dimensional1HNMR Studies on 2′5′-Dideoxyadenosylcobalamin

    Article • Spectroscopy Letters, February 1993, Taylor & Francis

    Hongzhe Sun