All Stories

  1. Cell-autonomous cytotoxicity of type I interferon responseviainduction of endoplasmic reticulum stress

    Article • The FASEB Journal, August 2017, Federation of American Societies For Experimental Biology (FASEB)

    Professor Hippokratis Kiaris

  2. Modeling estrogen receptor-positive breast cancers in mice: is it the best we can do?: Table 1

    Article • Endocrine Related Cancer, September 2016, Bioscientifica

    Professor Hippokratis Kiaris

  3. Peromyscus as a model of human disease

    Article • Seminars in Cell and Developmental Biology, June 2016, Elsevier

    Professor Hippokratis Kiaris

  4. Regulation of p21 during diabetes-associated stress of the endoplasmic reticulum

    Article • February 2015, Bioscientifica

    Professor Hippokratis Kiaris

  5. Improvement of chemotherapeutic drug efficacy by endoplasmic reticulum stress

    Article • February 2015, Bioscientifica

    Professor Hippokratis Kiaris

  6. Polycystin‐1 and polycystin‐2 are involved in the acquisition of aggressive phenotypes in colorectal cancer

    Article • International Journal of Cancer, September 2014, Wiley

    Professor Hippokratis Kiaris, Professor Athanasios G. Papavassiliou

  7. A crosstalk between p21 and UPR-induced transcription factor C/EBP homologous protein (CHOP) linked to type 2 diabetes

    Article • Biochimie, April 2014, Elsevier

    Professor Hippokratis Kiaris

  8. Advanced glycation end-products induce endoplasmic reticulum stress in human aortic endothelial cells

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), January 2014, De Gruyter

    Professor Hippokratis Kiaris

  9. Allelic Frequency in Human SNPs Predicts the Rate of Non-Synonymous Nucleotide Substitutions between Human and Chimpanzee Genes

    Article • Advances in Anthropology, January 2014, Scientific Research Publishing, Inc,

    Professor Hippokratis Kiaris

  10. Notch3 marks clonogenic mammary luminal progenitor cells in vivo

    Article • The Journal of Cell Biology, October 2013, Rockefeller University Press

    Professor Hippokratis Kiaris

  11. MicroRNAs in the tumour microenvironment: big role for small players

    Article • July 2013, Bioscientifica

    Professor Hippokratis Kiaris

  12. p53 antagonizes the unfolded protein response and inhibits ground glass hepatocyte development during endoplasmic reticulum stress

    Article • Experimental Biology and Medicine, October 2012, Frontiers

    Professor Hippokratis Kiaris

  13. Selection of p53-Deficient Stromal Cells in the Tumor Microenvironment

    Article • Genes & Cancer, September 2012, SAGE Publications

    Professor Hippokratis Kiaris

  14. Growth Hormone-Releasing Hormone Receptor Splice Variant 1 is Frequently Expressed in Oral Squamous Cell Carcinomas

    Article • Hormones and Cancer, March 2012, Springer Science + Business Media

    Professor Hippokratis Kiaris

  15. Tackling transcription factors: challenges in antitumor therapy

    Article • Trends in Molecular Medicine, October 2011, Elsevier

    Professor Hippokratis Kiaris

  16. Growth hormone-releasing hormone: not only a neurohormone

    Article • Trends in Endocrinology and Metabolism, August 2011, Elsevier

    Professor Hippokratis Kiaris

  17. ERp29 regulates response to doxorubicin by a PERK-mediated mechanism

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, June 2011, Elsevier

    Professor Hippokratis Kiaris

  18. p21/waf1 and smooth-muscle actin α expression in stromal fibroblasts of oral cancers

    Article • Cellular Oncology, May 2011, Springer Science + Business Media

    Professor Hippokratis Kiaris

  19. Immunohistochemical Expression of Notch Signaling in the Lining Epithelium of Periapical Cysts

    Article • Journal of Endodontics, February 2011, Elsevier

    Professor Hippokratis Kiaris

  20. GHRH and wound healing

    Article • Communicative & Integrative Biology, January 2011, Taylor & Francis

    Professor Hippokratis Kiaris

  21. Essential role for p53/p21-mediated signaling in the regulation of stromal fibroblast/cancer cell interaction and therapeutic efficacy

    Article • Cancer Genetics and Cytogenetics, November 2010, Elsevier

    Professor Hippokratis Kiaris

  22. Acceleration of wound healing by growth hormone-releasing hormone and its agonists

    Article • Proceedings of the National Academy of Sciences, October 2010, Proceedings of the National Academy of Sciences

    Professor Hippokratis Kiaris

  23. Atypical induction of the unfolded protein response by mifepristone

    Article • Endocrine, July 2010, Springer Science + Business Media

    Professor Hippokratis Kiaris

  24. Evaluation of Re and 99mTc Complexes of 2-(4′-Aminophenyl)benzothiazole as Potential Breast Cancer Radiopharmaceuticals

    Article • Journal of Medicinal Chemistry, June 2010, American Chemical Society (ACS)

    Professor Hippokratis Kiaris

  25. Editorial

    Article • Seminars in Cell and Developmental Biology, February 2010, Elsevier

    Professor Hippokratis Kiaris

  26. CHOP-dependent Regulation of p21/waf1 During ER Stress

    Article • Cellular Physiology and Biochemistry, January 2010, Cell Physiol Biochem Press GmbH and Co KG

    Professor Hippokratis Kiaris

  27. p21/waf1 and Smooth-Muscle Actin α Expression in Stromal Fibroblasts of Oral Cancers

    Article • Analytical Cellular Pathology, January 2010, Hindawi Publishing Corporation

    Professor Hippokratis Kiaris

  28. Regulation of Tumor-Stromal Fibroblast Interactions: Implications in Anticancer Therapy

    Article • Current Medicinal Chemistry, December 2008, Bentham Science Publishers

    Professor Hippokratis Kiaris

  29. Essential role of p21/waf1 in the mediation of the anti-proliferative effects of GHRH antagonist JMR-132

    Article • September 2008, Bioscientifica

    Professor Hippokratis Kiaris

  30. Expression of p21waf1/Cip1 in stromal fibroblasts of primary breast tumors

    Article • Human Molecular Genetics, August 2008, Oxford University Press (OUP)

    Professor Hippokratis Kiaris

  31. P53 mutations in stromal fibroblasts sensitize tumors against chemotherapy

    Article • International Journal of Cancer, June 2008, Wiley

    Professor Hippokratis Kiaris

  32. Fibroblast independency in tumors: implications in cancer therapy

    Article • Future Oncology, June 2008, Future Medicine

    Professor Hippokratis Kiaris

  33. ERp29, an endoplasmic reticulum secretion factor is involved in the growth of breast tumor xenografts

    Article • Molecular Carcinogenesis, April 2008, Wiley

    Professor Hippokratis Kiaris

  34. Expression of growth hormone–releasing hormone receptor splice variant 1 in primary human melanomas

    Article • Regulatory Peptides, April 2008, Elsevier

    Professor Hippokratis Kiaris

  35. Stimulation of proliferation of MCF-7 breast cancer cells by a transfected splice variant of growth hormone-releasing hormone receptor

    Article • Proceedings of the National Academy of Sciences, March 2007, Proceedings of the National Academy of Sciences

    Professor Hippokratis Kiaris

  36. Expression of ERp29, an Endoplasmic Reticulum Secretion Factor in Basal-Cell Carcinoma

    Article • American Journal of Dermatopathology, October 2006, Wolters Kluwer Health

    Professor Hippokratis Kiaris

  37. Expression of growth hormone-releasing hormone (GHRH) and splice variant of GHRH receptors in normal mouse tissues

    Article • Regulatory Peptides, September 2006, Elsevier

    Professor Hippokratis Kiaris

  38. Anatomically independent tumors revisited

    Article • Future Oncology, August 2006, Future Medicine

    Professor Hippokratis Kiaris

  39. Myc is a Notch1 transcriptional target and a requisite for Notch1-induced mammary tumorigenesis in mice

    Article • Proceedings of the National Academy of Sciences, June 2006, Proceedings of the National Academy of Sciences

    Professor Hippokratis Kiaris

  40. Editorial [Hot Topic: GHRH Analogs and Cancer (Guest Editor: Hippokratis Kiaris )]

    Article • Combinatorial Chemistry & High Throughput Screening, March 2006, Bentham Science Publishers

    Professor Hippokratis Kiaris

  41. Meet The Guest Editor

    Article • Combinatorial Chemistry & High Throughput Screening, March 2006, Bentham Science Publishers

    Professor Hippokratis Kiaris

  42. Estrogen receptor alpha gene polymorphism and systemic lupus erythematosus: a possible risk?

    Article • Lupus, May 2005, SAGE Publications

    Professor Hippokratis Kiaris

  43. Evidence for Nonautonomous Effect of p53 Tumor Suppressor in Carcinogenesis

    Article • Cancer Research, March 2005, American Association for Cancer Research (AACR)

    Professor Hippokratis Kiaris

  44. Extrapituitary Effects of the Growth Hormone-Releasing Hormone

    Article • January 2005, Elsevier

    Professor Hippokratis Kiaris

  45. Immunohistochemical detection of GHRH and its receptor splice variant 1 in primary human breast cancers

    Article • September 2004

    Professor Hippokratis Kiaris

  46. Modulation of Notch Signaling Elicits Signature Tumors and Inhibits Hras1-Induced Oncogenesis in the Mouse Mammary Epithelium

    Article • American Journal Of Pathology, August 2004, Elsevier

    Professor Hippokratis Kiaris

  47. Tumour–stroma interactions in carcinogenesis: Basic aspects and perspectives

    Article • Molecular and Cellular Biochemistry, June 2004, Springer Science + Business Media

    Professor Hippokratis Kiaris

  48. Growth hormone-releasing hormone and extra-pituitary tumorigenesis: therapeutic and diagnostic applications of growth hormone-releasing hormone antagonists

    Article • Expert Opinion on Investigational Drugs, August 2003, Informa Healthcare

    Professor Hippokratis Kiaris, Professor Michael Koutsilieris

  49. Ligand-dependent and -independent effects of splice variant 1 of growth hormone-releasing hormone receptor

    Article • Proceedings of the National Academy of Sciences, July 2003, Proceedings of the National Academy of Sciences

    Professor Hippokratis Kiaris

  50. Growth hormone-releasing hormone and extra-pituitary tumorigenesis: therapeutic and diagnostic applications of growth hormone-releasing hormone antagonists

    Article • Expert Opinion on Investigational Drugs, January 2003, Informa Healthcare

    Professor Hippokratis Kiaris, Professor Michael Koutsilieris

  51. Expression of growth hormone-releasing hormone in human primary endometrial carcinomas

    Article • September 2002

    Professor Hippokratis Kiaris

  52. Expression of a splice variant of the receptor for GHRH in 3T3 fibroblasts activates cell proliferation responses to GHRH analogs

    Article • Proceedings of the National Academy of Sciences, January 2002, Proceedings of the National Academy of Sciences

    Professor Hippokratis Kiaris

  53. A targeted cytotoxic somatostatin (SST) analogue, AN-238, inhibits the growth of H-69 small-cell lung carcinoma (SCLC) and H-157 non-SCLC in nude mice

    Article • European Journal of Cancer, March 2001, Elsevier

    Professor Hippokratis Kiaris

  54. Direct action of growth hormone-releasing hormone agonist JI-38 on normal human fibroblasts: Evidence from studies on cell proliferation and c-myc proto-oncogene expression

    Article • Regulatory Peptides, January 2001, Elsevier

    Professor Hippokratis Kiaris

  55. In vitro targeting of a cytotoxic analog of luteinizing hormone-releasing hormone AN-207 to ES-2 human ovarian cancer cells as demonstrated by microsatellite analyses

    Article • Anti-Cancer Drugs, January 2001, Wolters Kluwer Health

    Professor Hippokratis Kiaris

  56. Suppression of tumor growth by growth hormone-releasing hormone antagonist JV-1-36 does not involve the inhibition of autocrine production of insulin-like growth factor II in H-69 small cell lung carcinoma

    Article • Cancer Letters, December 2000, Elsevier

    Professor Hippokratis Kiaris

  57. Antagonists of Growth Hormone-Releasing Hormone Inhibit the Growth of U-87MG Human Glioblastoma in Nude Mice

    Article • Neoplasia, May 2000, Elsevier

    Professor Hippokratis Kiaris

  58. Growth hormone-releasing hormone: An autocrine growth factor for small cell lung carcinoma

    Article • Proceedings of the National Academy of Sciences, December 1999, Proceedings of the National Academy of Sciences

    Professor Hippokratis Kiaris

  59. Inhibition of growth of human malignant glioblastoma in nude mice by antagonists of bombesin/gastrin-releasing peptide

    Article • Oncogene, November 1999, Springer Science + Business Media

    Professor Hippokratis Kiaris

  60. Apoptosis Versus Necrosis: Which Should Be the Aim of Cancer Therapy?

    Article • Proceedings of The Society for Experimental Biology and Medicine, June 1999, Wiley

    Professor Hippokratis Kiaris

  61. Apoptosis Versus Necrosis: Which Should Be the Aim of Cancer Therapy?

    Article • Experimental Biology and Medicine, June 1999, Frontiers

    Professor Hippokratis Kiaris

  62. Inhibition of growth, production of insulin-like growth factor-II (IGF-II), and expression of IGF-II mRNA of human cancer cell lines by antagonistic analogs of growth hormone-releasing hormone in vitro

    Article • Proceedings of the National Academy of Sciences, March 1999, Proceedings of the National Academy of Sciences

    Professor Hippokratis Kiaris

  63. Decrease in telomerase activity in U-87MG human glioblastomas after treatment with an antagonist of growth hormone-releasing hormone

    Article • Proceedings of the National Academy of Sciences, January 1999, Proceedings of the National Academy of Sciences

    Professor Hippokratis Kiaris

  64. Genetic Instability in Renal Cell Carcinoma

    Article • European Urology, January 1998, Elsevier

    Professor Hippokratis Kiaris

  65. Microsatellite instability and loss of heterozygosity in human pterygia

    Article • British Journal of Ophthalmology, June 1997, BMJ

    Professor Hippokratis Kiaris

  66. Microsatellite Instability and Loss of Heterozygosity in Primary Breast Tumours

    Article • Tumor Biology, January 1997, Springer Science + Business Media

    Professor Hippokratis Kiaris

  67. Mutations and Expression of therasFamily Genes in Leukemias

    Article • Stem Cells, November 1996, Wiley

    Professor Hippokratis Kiaris

  68. TGF-beta 1 overexpression in breast cancer

    Article • Oncology Reports, November 1996, Spandidos Publications

    Professor Hippokratis Kiaris

  69. Transcriptional activation of H-ras, K-ras and N-ras proto-oncogenes in human bladder tumors

    Article • Cancer Letters, October 1996, Elsevier

    Professor Hippokratis Kiaris

  70. Instability at the H-ras minisatellite in human atherosclerotic plaques

    Article • Atherosclerosis, August 1996, Elsevier

    Professor Hippokratis Kiaris

  71. Loss of Heterozygosity and Microsatellite Instability in Human Atherosclerotic Plaques

    Article • Biochemical and Biophysical Research Communications, August 1996, Elsevier

    Professor Hippokratis Kiaris

  72. Quantitation of the allelic imbalance provides evidence on tumour heterogeneity: a hypothesis

    Article • Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, July 1996, Elsevier

    Professor Hippokratis Kiaris

  73. Microsatellite instability in patients with chronic obstructive pulmonary disease

    Article • Oncology Reports, May 1996, Spandidos Publications

    Professor Hippokratis Kiaris

  74. Detection of herpesvirus-like DNA sequences in Mediterranean Kaposi's sarcoma

    Article • Oncology Reports, March 1996, Spandidos Publications

    Professor Hippokratis Kiaris

  75. Microsatellite Instability in Human Atherosclerotic Plaques

    Article • Biochemical and Biophysical Research Communications, March 1996, Elsevier

    Professor Hippokratis Kiaris

  76. Loss of heterozygosity at 9p and 17q in human laryngeal tumours

    Article • Cancer Letters, October 1995, Elsevier

    Professor Hippokratis Kiaris

  77. MUTATIONS OF RAS GENES IN HUMAN TUMORS (REVIEW)

    Article • International Journal of Oncology, September 1995, Spandidos Publications

    Professor Hippokratis Kiaris

  78. DETECTION OF K-RAS MUTATIONS IN NONSMALL CELL LUNG-CARCINOMA

    Article • International Journal of Oncology, September 1995, Spandidos Publications

    Professor Hippokratis Kiaris

  79. DETECTION OF ACTIVATING MUTATIONS IN THE RAS FAMILY GENES IN CYTOLOGICAL SPECIMENS FROM LUNG-TUMORS

    Article • Oncology Reports, September 1995, Spandidos Publications

    Professor Hippokratis Kiaris

  80. INSTABILITY AT MICROSATELLITE SEQUENCES IN SPONTANEOUSLY ABORTED HUMAN EMBRYOS PROVIDES EVIDENCE FOR A NOVEL MECHANISM FOR RECURRENT MISCARRIAGES

    Article • Oncology Reports, September 1995, Spandidos Publications

    Professor Hippokratis Kiaris

  81. Instability at the H-ras Minisatellite Is Associated with the Spontaneous Abortion of the Embryo

    Article • Biochemical and Biophysical Research Communications, September 1995, Elsevier

    Professor Hippokratis Kiaris

  82. ANALYSIS OF H-RAS, K-RAS AND N-RAS GENES FOR EXPRESSION, MUTATION AND AMPLIFICATION IN LARYNGEAL TUMORS

    Article • International Journal of Oncology, July 1995, Spandidos Publications

    Professor Hippokratis Kiaris

  83. ACTIVATING MUTATIONS OF RAS FAMILY GENES IN PROSTATIC-CANCER

    Article • Oncology Reports, May 1995, Spandidos Publications

    Professor Hippokratis Kiaris

  84. LOSS OF HETEROZYGOSITY ON CHROMOSOME-8 IN SQUAMOUS-CELL CARCINOMAS OF THE HEAD AND NECK

    Article • International Journal of Oncology, December 1994, Spandidos Publications

    Professor Hippokratis Kiaris

  85. A METHOD TO DETECT AND QUANTITATE THE EXPRESSION OF NORMAL VERSUS MUTANT H-RAS TRANSCRIPTS AT CODON-12

    Article • International Journal of Oncology, September 1994, Spandidos Publications

    Professor Hippokratis Kiaris

  86. LOSS OF HETEROZYGOSITY AND MICROSATELLITE INSTABILITY OF THE H-RAS GENE IN CANCER OF THE HEAD AND NECK

    Article • International Journal of Oncology, September 1994, Spandidos Publications

    Professor Hippokratis Kiaris

  87. ACTIVATING MUTATIONS IN THE K-RAS GENE IN ULCERATIVE-COLITIS AND CROHNS-DISEASE

    Article • Oncology Reports, May 1994, Spandidos Publications

    Professor Hippokratis Kiaris

  88. RAS GENE-MUTATIONS ARE A RARE EVENT IN HUMAN UVEAL AND CUTANEOUS MELANOMAS

    Article • Oncology Reports, May 1994, Spandidos Publications

    Professor Hippokratis Kiaris