All Stories

  1. Antiviral Mx proteins have an ancient origin and widespread distribution among eukaryotes
  2. Widespread fungal–bacterial competition for magnesium lowers bacterial susceptibility to polymyxin antibiotics
  3. Indels allow antiviral proteins to evolve functional novelty inaccessible by missense mutations
  4. The diverse evolutionary histories of domesticated metaviral capsid genes in mammals
  5. Evolutionary origin and structural ligand mimicry by the inserted domain of alpha-integrin proteins
  6. Expansion and loss of sperm nuclear basic protein genes in Drosophila correspond with genetic conflicts between sex chromosomes
  7. Driving lessons: a brief (personal) history of centromere drive
  8. Recurrent but short-lived duplications of centromeric proteins in holocentric Caenorhabditis species
  9. Genetic conflicts between sex chromosomes drive expansion and loss of sperm nuclear basic protein genes in Drosophila
  10. Recurrent but short-lived duplications of centromeric proteins in holocentric Caenorhabditis species
  11. Novel Classes and Evolutionary Turnover of Histone H2B Variants in the Mammalian Germline
  12. The novel anti-CRISPR AcrIIA22 relieves DNA torsion in target plasmids and impairs SpyCas9 activity
  13. Novel classes and evolutionary turnover of histone H2B variants in the mammalian germline
  14. An actin-related protein that is most highly expressed in Drosophila testes is critical for embryonic development
  15. Gametic specialization of centromeric histone paralogs in Drosophila virilis
  16. Putting the brakes on centromere drive in Mimulus
  17. A balancing act between primate lentiviruses and their receptor
  18. Biparental contributions of the H2A.B histone variant control embryonic development in mice
  19. Innovation of heterochromatin functions drives rapid evolution of essential ZAD-ZNF genes in Drosophila
  20. A natural variant of the essential host gene MMS21 restricts the parasitic 2-micron plasmid in Saccharomyces cerevisiae
  21. AcrIIA22 is a novel anti-CRISPR that impairs SpyCas9 activity by relieving DNA torsion of target plasmids
  22. A rapidly evolving actin mediates fertility and developmental tradeoffs in Drosophila
  23. Mutational resilience of antiviral restriction favors primate TRIM5α in host-virus evolutionary arms races
  24. Innovation of heterochromatin functions drives rapid evolution of essential ZAD-ZNF genes in Drosophila
  25. Natural variation in an essential host gene contributes to parasitic plasmid resistance in Saccharomyces cerevisiae
  26. Ancient Coretention of Paralogs of Cid Centromeric Histones and Cal1 Chaperones in Mosquito Species
  27. Dynamic Evolution of De Novo DNA Methyltransferases in Rodent and Primate Genomes
  28. Hybridization promotes asexual reproduction in Caenorhabditis nematodes
  29. A Burst of Genetic Innovation in Drosophila Actin-Related Proteins for Testis-Specific Function
  30. Combinatorial mutagenesis of rapidly evolving residues yields super-restrictor antiviral proteins
  31. Dynamic evolution of de novo DNA methyltransferases in rodent and primate genomes
  32. Functional metagenomics-guided discovery of potent Cas9 inhibitors in the human microbiome
  33. A burst of genetic innovation in actin-related proteins (Arps) for testis-specific function in a Drosophila lineage
  34. Density-dependent resistance protects Legionella pneumophila from its own antimicrobial metabolite, HGA
  35. Cryptic asexual reproduction in Caenorhabditis nematodes revealed by interspecies hybridization
  36. Functional metagenomics-guided discovery of potent Cas9 inhibitors in the human microbiome
  37. Evolution-guided design of super-restrictor antiviral proteins reveals a breadth-versus-specificity tradeoff
  38. Gametic specialization of centromeric histone paralogs in Drosophila virilis
  39. Density-dependent resistance protects Legionella pneumophila from its own antimicrobial metabolite, HGA
  40. Evolutionary origins and diversification of testis-specific short histone H2A variants in mammals
  41. Culture shock
  42. Evolutionary origins and diversification of testis-specific short histone H2A variants in mammals
  43. The gene drive bubble: New realities
  44. wtf genes are prolific dual poison-antidote meiotic drivers
  45. Recurrent Gene Duplication Leads to Diverse Repertoires of Centromeric Histones in Drosophila Species
  46. Genetic conflicts: the usual suspects and beyond
  47. The piggyBac transposon-derived genes TPB1 and TPB6 mediate essential transposon-like excision during the developmental rearrangement of key genes in Tetrahymena thermophila ...
  48. Recurrent gene duplication leads to diverse repertoires of centromeric histones in Drosophila species
  49. A mitochondrial DNA hypomorph of cytochrome oxidase specifically impairs male fertility inDrosophila melanogaster
  50. Evolution-guided functional analyses reveal diverse antiviral specificities encoded by IFIT1 genes in mammals
  51. Evolution of a transcriptional regulator from a transmembrane nucleoporin
  52. Conservation and Innovation of APOBEC3A Restriction Functions during Primate Evolution
  53. Hide and seek: how chromatin-based pathways silence retroelements in the mammalian germline
  54. Recurrent gene duplication diversifies genome defense repertoire in Drosophila
  55. Evolutionary Turnover of Kinetochore Proteins: A Ship of Theseus?
  56. An essential cell cycle regulation gene causes hybrid inviability in Drosophila
  57. Evolutionary Analyses Suggest a Function of MxB Immunity Proteins Beyond Lentivirus Restriction
  58. Chromosome Segregation: Human Female Meiosis Breaks All the Rules
  59. LINE-1 Retroelements Get ZAPped!
  60. Mitotic fidelity requires transgenerational action of a testis-restricted HP1
  61. R2d2 and Hyperdrive Mechanisms (in Mouse Meiosis)
  62. Speciation via Autoimmunity: A Dangerous Mix
  63. Transferred interbacterial antagonism genes augment eukaryotic innate immune function
  64. Genetic Conflicts: Stronger Centromeres Win Tug-of-War in Female Meiosis
  65. Recurrent loss of CenH3 is associated with independent transitions to holocentricity in insects
  66. How a Virus Blocks a Cellular Emergency Access Lane to the Nucleus, STAT!
  67. Genome rearrangements and pervasive meiotic drive cause hybrid infertility in fission yeast
  68. Rapid Evolution of PARP Genes Suggests a Broad Role for ADP-Ribosylation in Host-Virus Conflicts
  69. Molecular Basis for Specific Recognition of Bacterial Ligands by NAIP/NLRC4 Inflammasomes
  70. Mobile DNA: an evolving field
  71. Mobile genetic elements and genome evolution 2014
  72. An Evolutionary Screen Highlights Canonical and Noncanonical Candidate Antiviral Genes within the Primate TRIM Gene Family
  73. Host gene evolution traces the evolutionary history of ancient primate lentiviruses
  74. An evolutionary perspective on the broad antiviral specificity of MxA
  75. A rapidly evolving genomic toolkit forDrosophilaheterochromatin
  76. Identification of an overprinting gene in Merkel cell polyomavirus provides evolutionary insight into the birth of viral genes
  77. Stepwise Evolution of Essential Centromere Function in a Drosophila Neogene
  78. Birth, decay, and reconstruction of an ancient TRIMCyp gene fusion in primate genomes
  79. Rules of Engagement: Molecular Insights from Host-Virus Arms Races
  80. Extensive evolutionary and functional diversity among mammalian AIM2-like receptors
  81. Evolution-Guided Identification of Antiviral Specificity Determinants in the Broadly Acting Interferon-Induced Innate Immunity Factor MxA
  82. Poxviruses Deploy Genomic Accordions to Adapt Rapidly against Host Antiviral Defenses
  83. Rapid evolution of centromeres and centromeric/kinetochore proteins
  84. The function and evolution of the restriction factor viperin in primates was not driven by lentiviruses
  85. Phylogenomic Analysis Reveals Dynamic Evolutionary History of the Drosophila Heterochromatin Protein 1 (HP1) Gene Family
  86. A unified phylogeny-based nomenclature for histone variants
  87. Convergent Evolution of Escape from Hepaciviral Antagonism in Primates
  88. The Ability of Primate Lentiviruses to Degrade the Monocyte Restriction Factor SAMHD1 Preceded the Birth of the Viral Accessory Protein Vpx
  89. Retroviruses push the envelope for mammalian placentation
  90. Birth, Death, and Replacement of Karyopherins in Drosophila
  91. Learning to Protect Your Genome on the Fly
  92. Adaptive Evolution of Centromeric Proteins
  93. Paleovirology—ghosts and gifts of viruses past
  94. The Breadth of Antiviral Activity of Apobec3DE in Chimpanzees Has Been Driven by Positive Selection
  95. Absence of Positive Selection on Centromeric Histones in Tetrahymena Suggests Unsuppressed Centromere-Drive in Lineages Lacking Male Meiosis
  96. Ancient Adaptive Evolution of Tetherin Shaped the Functions of Vpu and Nef in Human Immunodeficiency Virus and Primate Lentiviruses
  97. Paleovirology—Modern Consequences of Ancient Viruses
  98. Diversifying selection and functional analysis of interleukin-4 suggests antagonism-driven evolution at receptor-binding interfaces
  99. Accelerated Evolution of the Prdm9 Speciation Gene across Diverse Metazoan Taxa
  100. Multiple Roles for Heterochromatin Protein 1 Genes inDrosophila
  101. Diamonds and rust: how transposable elements influence mammalian genomes
  102. Altered Heterochromatin Binding by a Hybrid Sterility Protein in Drosophila Sibling Species
  103. The evolutionary conundrum of pathogen mimicry
  104. Major Evolutionary Transitions in Centromere Complexity
  105. Evolution of TRIM antiviral genes in primate genomes
  106. A Surrogate Approach to Study the Evolution of Noncoding DNA Elements That Organize Eukaryotic Genomes
  107. The apolipoprotein L family of programmed cell death and immunity genes rapidly evolved in primates at discrete sites of host-pathogen interactions
  108. An expanded clade of rodent Trim5 genes
  109. The Centromere-Drive Hypothesis: A Simple Basis for Centromere Complexity
  110. Protein kinase R reveals an evolutionary model for defeating viral mimicry
  111. Guidelines for Naming Nonprimate APOBEC3 Genes and Proteins
  112. Antiretroelement Activity of APOBEC3H Was Lost Twice in Recent Human Evolution
  113. The Evolution of Centromeric DNA Sequences
  114. Positive Selection and Increased Antiviral Activity Associated with the PARP-Containing Isoform of Human Zinc-Finger Antiviral Protein
  115. Discordant Evolution of the Adjacent Antiretroviral Genes TRIM22 and TRIM5 in Mammals
  116. Species-specific positive selection of the male-specific lethal complex that participates in dosage compensation in Drosophila
  117. Restriction of an Extinct Retrovirus by the Human TRIM5  Antiviral Protein
  118. Molecular Evolution of Drosophilacdc6, an Essential DNA Replication-Licensing Gene, Suggests an Adaptive Choice of Replication Origins
  119. Genes get diabolical
  120. Positive selection of yeast nonhomologous end-joining genes and a retrotransposon conflict hypothesis
  121. A hitchhiker's guide to survival finally makes CENs
  122. Genetic conflicts during meiosis and the evolutionary origins of centromere complexity: Figure 1
  123. Adaptive Evolution and Antiviral Activity of the Conserved Mammalian Cytidine Deaminase APOBEC3H
  124. High-Frequency Persistence of an Impaired Allele of the Retroviral Defense Gene TRIM5α in Humans
  125. The CNA1 Histone of the Ciliate Tetrahymena thermophila Is Essential for Chromosome Segregation in the Germline Micronucleus
  126. finds centromeres in the driver's seat
  127. Positive selection of primate TRIM5 α identifies a critical species-specific retroviral restriction domain
  128. Ribonuclease H evolution in retrotransposable elements
  129. Positive Selection of Iris, a Retroviral Envelope–Derived Host Gene in Drosophila melanogaster
  130. Positive Selection Drives the Evolution of rhino, a Member of the Heterochromatin Protein 1 Family in Drosophila
  131. Ancient Adaptive Evolution of the Primate Antiviral DNA-Editing Enzyme APOBEC3G
  132. Phylogenomics of the nucleosome
  133. Identification of the yeast gene encoding the tRNA m1G methyltransferase responsible for modification at position 9
  134. Conflict begets complexity: the evolution of centromeres
  135. Centromeres: Selfish drivers
  136. Recurrent evolution of DNA-binding motifs in the Drosophila centromeric histone
  137. Origins and Evolution of Retrotransposons
  138. Speciation and Centromere Evolution
  139. The Centromere Paradox: Stable Inheritance with Rapidly Evolving DNA
  140. Phylogenetic Analysis of Ribonuclease H Domains Suggests a Late, Chimeric Origin of LTR Retrotransposable Elements and Retroviruses
  141. Ten-Kilodalton Domain in Ty3 Gag3-Pol3p between PR and RT Is Dispensable for Ty3 Transposition
  142. Dual recognition–incision enzymes might be involved in mismatch repair and meiosis
  143. Poised for Contagion: Evolutionary Origins of the Infectious Abilities of Invertebrate Retroviruses
  144. Putative telomerase catalytic subunits from Giardia lamblia and Caenorhabditis elegans
  145. A functional homolog of a yeast tRNA splicing enzyme is conserved in higher eukaryotes and in Escherichia coli
  146. Are retrotransposons long-term hitchhikers?
  147. Evolutionary specialization of the nuclear targeting apparatus