All Stories

  1. Heterozygous and generalist MxA super-restrictors overcome breadth-specificity tradeoffs in antiviral restriction
  2. TheDrosophilamaternal-effect geneabnormal oocyte(ao) does not repress histone gene expression
  3. Antiviral Mx proteins have an ancient origin and widespread distribution among eukaryotes
  4. Widespread fungal–bacterial competition for magnesium lowers bacterial susceptibility to polymyxin antibiotics
  5. Indels allow antiviral proteins to evolve functional novelty inaccessible by missense mutations
  6. The diverse evolutionary histories of domesticated metaviral capsid genes in mammals
  7. Evolutionary origin and structural ligand mimicry by the inserted domain of alpha-integrin proteins
  8. Expansion and loss of sperm nuclear basic protein genes in Drosophila correspond with genetic conflicts between sex chromosomes
  9. Driving lessons: a brief (personal) history of centromere drive
  10. Recurrent but short-lived duplications of centromeric proteins in holocentric Caenorhabditis species
  11. Genetic conflicts between sex chromosomes drive expansion and loss of sperm nuclear basic protein genes in Drosophila
  12. Recurrent but short-lived duplications of centromeric proteins in holocentric Caenorhabditis species
  13. Novel Classes and Evolutionary Turnover of Histone H2B Variants in the Mammalian Germline
  14. The novel anti-CRISPR AcrIIA22 relieves DNA torsion in target plasmids and impairs SpyCas9 activity
  15. Novel classes and evolutionary turnover of histone H2B variants in the mammalian germline
  16. An actin-related protein that is most highly expressed in Drosophila testes is critical for embryonic development
  17. Gametic specialization of centromeric histone paralogs in Drosophila virilis
  18. Putting the brakes on centromere drive in Mimulus
  19. A balancing act between primate lentiviruses and their receptor
  20. Biparental contributions of the H2A.B histone variant control embryonic development in mice
  21. Innovation of heterochromatin functions drives rapid evolution of essential ZAD-ZNF genes in Drosophila
  22. A natural variant of the essential host gene MMS21 restricts the parasitic 2-micron plasmid in Saccharomyces cerevisiae
  23. AcrIIA22 is a novel anti-CRISPR that impairs SpyCas9 activity by relieving DNA torsion of target plasmids
  24. A rapidly evolving actin mediates fertility and developmental tradeoffs in Drosophila
  25. Mutational resilience of antiviral restriction favors primate TRIM5α in host-virus evolutionary arms races
  26. Innovation of heterochromatin functions drives rapid evolution of essential ZAD-ZNF genes in Drosophila
  27. Natural variation in an essential host gene contributes to parasitic plasmid resistance in Saccharomyces cerevisiae
  28. Ancient Coretention of Paralogs of Cid Centromeric Histones and Cal1 Chaperones in Mosquito Species
  29. Dynamic Evolution of De Novo DNA Methyltransferases in Rodent and Primate Genomes
  30. Hybridization promotes asexual reproduction in Caenorhabditis nematodes
  31. A Burst of Genetic Innovation in Drosophila Actin-Related Proteins for Testis-Specific Function
  32. Combinatorial mutagenesis of rapidly evolving residues yields super-restrictor antiviral proteins
  33. Dynamic evolution of de novo DNA methyltransferases in rodent and primate genomes
  34. Functional metagenomics-guided discovery of potent Cas9 inhibitors in the human microbiome
  35. A burst of genetic innovation in actin-related proteins (Arps) for testis-specific function in a Drosophila lineage
  36. Density-dependent resistance protects Legionella pneumophila from its own antimicrobial metabolite, HGA
  37. Cryptic asexual reproduction in Caenorhabditis nematodes revealed by interspecies hybridization
  38. Functional metagenomics-guided discovery of potent Cas9 inhibitors in the human microbiome
  39. Evolution-guided design of super-restrictor antiviral proteins reveals a breadth-versus-specificity tradeoff
  40. Gametic specialization of centromeric histone paralogs in Drosophila virilis
  41. Density-dependent resistance protects Legionella pneumophila from its own antimicrobial metabolite, HGA
  42. Evolutionary origins and diversification of testis-specific short histone H2A variants in mammals
  43. Culture shock
  44. Evolutionary origins and diversification of testis-specific short histone H2A variants in mammals
  45. The gene drive bubble: New realities
  46. wtf genes are prolific dual poison-antidote meiotic drivers
  47. Recurrent Gene Duplication Leads to Diverse Repertoires of Centromeric Histones in Drosophila Species
  48. Genetic conflicts: the usual suspects and beyond
  49. The piggyBac transposon-derived genes TPB1 and TPB6 mediate essential transposon-like excision during the developmental rearrangement of key genes in Tetrahymena thermophila ...
  50. Recurrent gene duplication leads to diverse repertoires of centromeric histones in Drosophila species
  51. A mitochondrial DNA hypomorph of cytochrome oxidase specifically impairs male fertility inDrosophila melanogaster
  52. Evolution-guided functional analyses reveal diverse antiviral specificities encoded by IFIT1 genes in mammals
  53. Evolution of a transcriptional regulator from a transmembrane nucleoporin
  54. Conservation and Innovation of APOBEC3A Restriction Functions during Primate Evolution
  55. Hide and seek: how chromatin-based pathways silence retroelements in the mammalian germline
  56. Recurrent gene duplication diversifies genome defense repertoire in Drosophila
  57. Evolutionary Turnover of Kinetochore Proteins: A Ship of Theseus?
  58. An essential cell cycle regulation gene causes hybrid inviability in Drosophila
  59. Evolutionary Analyses Suggest a Function of MxB Immunity Proteins Beyond Lentivirus Restriction
  60. Chromosome Segregation: Human Female Meiosis Breaks All the Rules
  61. LINE-1 Retroelements Get ZAPped!
  62. Mitotic fidelity requires transgenerational action of a testis-restricted HP1
  63. R2d2 and Hyperdrive Mechanisms (in Mouse Meiosis)
  64. Speciation via Autoimmunity: A Dangerous Mix
  65. Transferred interbacterial antagonism genes augment eukaryotic innate immune function
  66. Genetic Conflicts: Stronger Centromeres Win Tug-of-War in Female Meiosis
  67. Recurrent loss of CenH3 is associated with independent transitions to holocentricity in insects
  68. How a Virus Blocks a Cellular Emergency Access Lane to the Nucleus, STAT!
  69. Genome rearrangements and pervasive meiotic drive cause hybrid infertility in fission yeast
  70. Rapid Evolution of PARP Genes Suggests a Broad Role for ADP-Ribosylation in Host-Virus Conflicts
  71. Molecular Basis for Specific Recognition of Bacterial Ligands by NAIP/NLRC4 Inflammasomes
  72. Mobile DNA: an evolving field
  73. Mobile genetic elements and genome evolution 2014
  74. An Evolutionary Screen Highlights Canonical and Noncanonical Candidate Antiviral Genes within the Primate TRIM Gene Family
  75. Host gene evolution traces the evolutionary history of ancient primate lentiviruses
  76. An evolutionary perspective on the broad antiviral specificity of MxA
  77. A rapidly evolving genomic toolkit forDrosophilaheterochromatin
  78. Identification of an overprinting gene in Merkel cell polyomavirus provides evolutionary insight into the birth of viral genes
  79. Stepwise Evolution of Essential Centromere Function in a Drosophila Neogene
  80. Birth, decay, and reconstruction of an ancient TRIMCyp gene fusion in primate genomes
  81. Rules of Engagement: Molecular Insights from Host-Virus Arms Races
  82. Extensive evolutionary and functional diversity among mammalian AIM2-like receptors
  83. Evolution-Guided Identification of Antiviral Specificity Determinants in the Broadly Acting Interferon-Induced Innate Immunity Factor MxA
  84. Poxviruses Deploy Genomic Accordions to Adapt Rapidly against Host Antiviral Defenses
  85. Rapid evolution of centromeres and centromeric/kinetochore proteins
  86. The function and evolution of the restriction factor viperin in primates was not driven by lentiviruses
  87. Phylogenomic Analysis Reveals Dynamic Evolutionary History of the Drosophila Heterochromatin Protein 1 (HP1) Gene Family
  88. A unified phylogeny-based nomenclature for histone variants
  89. Convergent Evolution of Escape from Hepaciviral Antagonism in Primates
  90. The Ability of Primate Lentiviruses to Degrade the Monocyte Restriction Factor SAMHD1 Preceded the Birth of the Viral Accessory Protein Vpx
  91. Retroviruses push the envelope for mammalian placentation
  92. Birth, Death, and Replacement of Karyopherins in Drosophila
  93. Learning to Protect Your Genome on the Fly
  94. Adaptive Evolution of Centromeric Proteins
  95. Paleovirology—ghosts and gifts of viruses past
  96. The Breadth of Antiviral Activity of Apobec3DE in Chimpanzees Has Been Driven by Positive Selection
  97. Absence of Positive Selection on Centromeric Histones in Tetrahymena Suggests Unsuppressed Centromere-Drive in Lineages Lacking Male Meiosis
  98. Ancient Adaptive Evolution of Tetherin Shaped the Functions of Vpu and Nef in Human Immunodeficiency Virus and Primate Lentiviruses
  99. Paleovirology—Modern Consequences of Ancient Viruses
  100. Diversifying selection and functional analysis of interleukin-4 suggests antagonism-driven evolution at receptor-binding interfaces
  101. Accelerated Evolution of the Prdm9 Speciation Gene across Diverse Metazoan Taxa
  102. Multiple Roles for Heterochromatin Protein 1 Genes inDrosophila
  103. Diamonds and rust: how transposable elements influence mammalian genomes
  104. Altered Heterochromatin Binding by a Hybrid Sterility Protein in Drosophila Sibling Species
  105. The evolutionary conundrum of pathogen mimicry
  106. Major Evolutionary Transitions in Centromere Complexity
  107. Evolution of TRIM antiviral genes in primate genomes
  108. A Surrogate Approach to Study the Evolution of Noncoding DNA Elements That Organize Eukaryotic Genomes
  109. The apolipoprotein L family of programmed cell death and immunity genes rapidly evolved in primates at discrete sites of host-pathogen interactions
  110. An expanded clade of rodent Trim5 genes
  111. The Centromere-Drive Hypothesis: A Simple Basis for Centromere Complexity
  112. Protein kinase R reveals an evolutionary model for defeating viral mimicry
  113. Guidelines for Naming Nonprimate APOBEC3 Genes and Proteins
  114. Antiretroelement Activity of APOBEC3H Was Lost Twice in Recent Human Evolution
  115. The Evolution of Centromeric DNA Sequences
  116. Positive Selection and Increased Antiviral Activity Associated with the PARP-Containing Isoform of Human Zinc-Finger Antiviral Protein
  117. Discordant Evolution of the Adjacent Antiretroviral Genes TRIM22 and TRIM5 in Mammals
  118. Species-specific positive selection of the male-specific lethal complex that participates in dosage compensation in Drosophila
  119. Restriction of an Extinct Retrovirus by the Human TRIM5  Antiviral Protein
  120. Molecular Evolution of Drosophilacdc6, an Essential DNA Replication-Licensing Gene, Suggests an Adaptive Choice of Replication Origins
  121. Genes get diabolical
  122. Positive selection of yeast nonhomologous end-joining genes and a retrotransposon conflict hypothesis
  123. A hitchhiker's guide to survival finally makes CENs
  124. Genetic conflicts during meiosis and the evolutionary origins of centromere complexity: Figure 1
  125. Adaptive Evolution and Antiviral Activity of the Conserved Mammalian Cytidine Deaminase APOBEC3H
  126. High-Frequency Persistence of an Impaired Allele of the Retroviral Defense Gene TRIM5α in Humans
  127. The CNA1 Histone of the Ciliate Tetrahymena thermophila Is Essential for Chromosome Segregation in the Germline Micronucleus
  128. finds centromeres in the driver's seat
  129. Positive selection of primate TRIM5 α identifies a critical species-specific retroviral restriction domain
  130. Ribonuclease H evolution in retrotransposable elements
  131. Positive Selection of Iris, a Retroviral Envelope–Derived Host Gene in Drosophila melanogaster
  132. Positive Selection Drives the Evolution of rhino, a Member of the Heterochromatin Protein 1 Family in Drosophila
  133. Ancient Adaptive Evolution of the Primate Antiviral DNA-Editing Enzyme APOBEC3G
  134. Phylogenomics of the nucleosome
  135. Identification of the yeast gene encoding the tRNA m1G methyltransferase responsible for modification at position 9
  136. Conflict begets complexity: the evolution of centromeres
  137. Centromeres: Selfish drivers
  138. Recurrent evolution of DNA-binding motifs in the Drosophila centromeric histone
  139. Origins and Evolution of Retrotransposons
  140. Speciation and Centromere Evolution
  141. The Centromere Paradox: Stable Inheritance with Rapidly Evolving DNA
  142. Phylogenetic Analysis of Ribonuclease H Domains Suggests a Late, Chimeric Origin of LTR Retrotransposable Elements and Retroviruses
  143. Ten-Kilodalton Domain in Ty3 Gag3-Pol3p between PR and RT Is Dispensable for Ty3 Transposition
  144. Dual recognition–incision enzymes might be involved in mismatch repair and meiosis
  145. Poised for Contagion: Evolutionary Origins of the Infectious Abilities of Invertebrate Retroviruses
  146. Putative telomerase catalytic subunits from Giardia lamblia and Caenorhabditis elegans
  147. A functional homolog of a yeast tRNA splicing enzyme is conserved in higher eukaryotes and in Escherichia coli
  148. Are retrotransposons long-term hitchhikers?
  149. Evolutionary specialization of the nuclear targeting apparatus