All Stories

  1. The Pathologist Counts—So Many Variables in the Risk Stratification of Thyroid Cancers

    Article • The Journal of Clinical Endocrinology & Metabolism, May 2024, Endocrine Society

    Dr. Giorgio Grani

  2. Ontology-Based Data Preparation in Healthcare: The Case of the AMD-STITCH Project

    Article • SN Computer Science, April 2024, Springer Science + Business Media

    Dr. Giorgio Grani

  3. Drawing as a Way of Knowing: How a Mapping Model Assists Preoperative Evaluation of Patients with Thyroid Carcinoma

    Article • Journal of Clinical Medicine, February 2024, MDPI AG

    Dr. Giorgio Grani

  4. A Prospective Multicenter Study Examining the Relationship Between Thyroid Cancer Treatment Outcomes and the Presence of Autoimmune Thyroiditis

    Article • Thyroid, November 2023, Mary Ann Liebert Inc

    Dr. Giorgio Grani

  5. International Expert Consensus on US Lexicon for Thyroid Nodules

    Article • Radiology, October 2023, Radiological Society of North America (RSNA)

    Dr. Giorgio Grani

  6. Laterocervical lymph node metastases from suspected thyroidal primary site that turned out to be metastases of lung cancer: A case report

    Article • Clinical Case Reports, July 2023, Wiley

    Dr. Giorgio Grani

  7. The effects of multitarget kinase inhibitors on glucose, cholesterol, and triglyceride levels

    Article • Endocrine, April 2023, Springer Science + Business Media

    Dr. Giorgio Grani

  8. Ultrasound screening for thyroid nodules and cancer in individuals with family history of thyroid cancer: a micro-costing approach

    Article • Journal of Endocrinological Investigation, April 2023, Springer Science + Business Media

    Dr. Giorgio Grani

  9. A Reappraisal of Suspicious Sonographic Features of Thyroid Nodules: Shape Is Not an Independent Predictor of Malignancy

    Article • The Journal of Clinical Endocrinology & Metabolism, February 2023, Endocrine Society

    Dr. Giorgio Grani

  10. Predicting recurrence of thyroid cancer: how to.

    Article • The Journal of Clinical Endocrinology & Metabolism, February 2023, Endocrine Society

    Dr. Giorgio Grani

  11. Prevalence of Thyroid Nodules and Thyroid Cancer in Individuals with a First-Degree Family History of Non-Medullary Thyroid Cancer: A Cross-Sectional Study Based on Sonographic Screening

    Article • Thyroid, November 2022, Mary Ann Liebert Inc

    Dr. Giorgio Grani

  12. Size Doesn't Matter! Is Active Surveillance Feasible for Low-Risk Thyroid Cancers up to 20 mm?

    Article • Clinical Thyroidology, November 2022, Mary Ann Liebert Inc

    Dr. Giorgio Grani

  13. What Is the Risk of Missed Malignancies in the Longterm Follow-up of Thyroid Nodules?

    Article • Clinical Thyroidology, September 2022, Mary Ann Liebert Inc

    Dr. Giorgio Grani

  14. Precision oncology for RET-related tumors

    Article • Frontiers in Oncology, August 2022, Frontiers

    Dr. Giorgio Grani

  15. New hope for patients with BRAF V600E-mutant anaplastic thyroid cancer: lights and shadows

    Article • Annals of Palliative Medicine, August 2022, AME Publishing Company

    Dr. Giorgio Grani

  16. The legacy of the COVID-19 pandemics for thyroid cancer patients: towards the application of clinical practice recommendations

    Article • Endocrine, July 2022, Springer Science + Business Media

    Dr. Giorgio Grani

  17. Artificial Intelligence for Thyroid Nodule Characterization: Where Are We Standing?

    Article • Cancers, July 2022, MDPI AG

    Dr. Giorgio Grani, Professor Fabrizio Frezza

  18. The COVID-19 outbreak and de-escalation of thyroid cancer diagnosis and treatment

    Article • Endocrine, July 2022, Springer Science + Business Media

    Dr. Giorgio Grani

  19. Is Lenvatinib Better Than Sorafenib as First-Line Treatment of Radioiodine Refractory Differentiated Thyroid Cancers?

    Article • Clinical Thyroidology, July 2022, Mary Ann Liebert Inc

    Dr. Giorgio Grani

  20. Establishment and maintenance of thyroid organoids from human cancer cells

    Article • STAR Protocols, June 2022, Elsevier

    Dr. Giorgio Grani

  21. Diagnostic accuracy of ultrasonographic features in detecting thyroid cancer in the transition age: a meta-analysis

    Article • European Thyroid Journal, June 2022, Bioscientifica

    Dr. Giorgio Grani

  22. Levothyroxine Treatment of Subclinical Hypothyroidism in the Elderly Does Not Improve Hemoglobin Levels

    Article • Clinical Thyroidology, May 2022, Mary Ann Liebert Inc

    Dr. Giorgio Grani

  23. Multimodal Feature Fusion and Knowledge-Driven Learning via Experts Consult for Thyroid Nodule Classification

    Article • IEEE Transactions on Circuits and Systems for Video Technology, May 2022, Institute of Electrical & Electronics Engineers (IEEE)

    Dr. Giorgio Grani

  24. A Network-Based Analysis of Disease Modules From a Taxonomic Perspective

    Article • IEEE Journal of Biomedical and Health Informatics, April 2022, Institute of Electrical & Electronics Engineers (IEEE)

    Dr. Giorgio Grani

  25. US-Elastography With Different Techniques for Thyroid Nodule Characterization: Systematic Review and Meta-analysis

    Article • Frontiers in Oncology, March 2022, Frontiers

    annalisa de silvestri, Dr. Giorgio Grani

  26. 18F–FDG–PET/CT May Reduce Unnecessary Thyroid Surgery in Cytologically Indeterminate Thyroid Nodules

    Article • Clinical Thyroidology, March 2022, Mary Ann Liebert Inc

    Dr. Giorgio Grani

  27. Non-Marked Hypoechogenic Nodules: Multicenter Study on the Thyroid Malignancy Risk Stratification and Accuracy Based on TIRADS Systems Comparison

    Article • Medicina, February 2022, MDPI AG

    Dr. Giorgio Grani

  28. Supporting Personalized Health Care With Social Media Analytics: An Application to Hypothyroidism

    Article • ACM Transactions on Computing for Healthcare, January 2022, ACM (Association for Computing Machinery)

    Paola Velardi, Dr. Giorgio Grani

  29. Inappropriate Use of Thyroid Ultrasound Is Common in Clinical Practice

    Article • Clinical Thyroidology, January 2022, Mary Ann Liebert Inc

    Dr. Giorgio Grani

  30. Management of cytologically indeterminate thyroid nodules: <i>primum non nocere</i>

    Article • Polish Archives of Internal Medicine, December 2021, Towarzystwo Internistow Polskich/Polish Society of Internal Medicine

    Dr. Giorgio Grani

  31. Minimal Extrathyroidal Extension in Predicting 1-Year Outcomes: A Longitudinal Multicenter Study of Low-to-Intermediate-Risk Papillary Thyroid Carcinoma (ITCO#4)

    Article • Thyroid, December 2021, Mary Ann Liebert Inc

    Dr. Giorgio Grani

  32. Preoperative Ultrasonography in the Evaluation of Suspected Familial Non-Medullary Thyroid Cancer: Are We Able to Predict Multifocality and Extrathyroidal Extension?

    Article • Journal of Clinical Medicine, November 2021, MDPI AG

    Dr. Giorgio Grani

  33. Integrating categorical and structural proximity in Disease Ontologies

    Article • November 2021, Institute of Electrical & Electronics Engineers (IEEE)

    Dr. Giorgio Grani

  34. Thyroid Nodule Characterization: How to Assess the Malignancy Risk. Update of the Literature

    Article • Diagnostics, July 2021, MDPI AG

    Dr. Giorgio Grani

  35. TIRADS, SRE and SWE in INDETERMINATE thyroid nodule characterization: Which has better diagnostic performance?

    Article • La radiologia medica, June 2021, Springer Science + Business Media

    Dr. Giorgio Grani

  36. Real-World Performance of the American Thyroid Association Risk Estimates in Predicting 1-Year Differentiated Thyroid Cancer Outcomes: A Prospective Multicenter Study of 2000 Patients

    Article • Thyroid, February 2021, Mary Ann Liebert Inc

    Professor Fabio Monzani, Dr. Giorgio Grani

  37. Safety and Quality-of-Life Data from an Italian Expanded Access Program of Lenvatinib for Treatment of Thyroid Cancer

    Article • Thyroid, February 2021, Mary Ann Liebert Inc

    Dr. Giorgio Grani

  38. Molecular analysis of fine-needle aspiration cytology in thyroid disease: where are we?

    Article • Current Opinion in Otolaryngology & Head & Neck Surgery, January 2021, Wolters Kluwer Health

    Dr. Giorgio Grani

  39. Selective Use of Radioactive Iodine Therapy for Papillary Thyroid Cancers With Low or Lower-Intermediate Recurrence Risk

    Article • The Journal of Clinical Endocrinology & Metabolism, December 2020, Endocrine Society

    Dr. Giorgio Grani

  40. The ultrasound risk stratification systems for thyroid nodule have been evaluated against papillary carcinoma. A meta-analysis

    Article • Reviews in Endocrine and Metabolic Disorders, September 2020, Springer Science + Business Media

    Dr. Giorgio Grani

  41. Performance of EU-TIRADS in malignancy risk stratification of thyroid nodules: a meta-analysis

    Article • European Journal of Endocrinology, September 2020, Oxford University Press (OUP)

    Dr. Giorgio Grani

  42. Sonographic Risk Stratification Systems for Thyroid Nodules as Rule-Out Tests in Older Adults

    Article • Cancers, August 2020, MDPI AG

    Dr. Giorgio Grani

  43. Artificial Intelligence: What Is It and How Can It Expand the Ultrasound Potential in the Future?

    Article • Ultraschall in der Medizin - European Journal of Ultrasound, August 2020, Thieme Publishing Group

    Dr. Giorgio Grani

  44. Loss of Function SETD2 Mutations in Poorly Differentiated Metastases from Two Hürthle Cell Carcinomas of the Thyroid

    Article • Cancers, July 2020, MDPI AG

    Dr. Giorgio Grani

  45. Cancer Care During COVID-19 Era: The Quality of Life of Patients With Thyroid Malignancies

    Article • Frontiers in Oncology, June 2020, Frontiers

    Dr. Giorgio Grani

  46. Analytical validation of a novel targeted next-generation sequencing assay for mutation detection in thyroid nodule aspirates and tissue

    Article • Endocrine, June 2020, Springer Science + Business Media

    Dr. Giorgio Grani

  47. Contemporary Thyroid Nodule Evaluation and Management

    Article • The Journal of Clinical Endocrinology & Metabolism, June 2020, Endocrine Society

    Dr. Giorgio Grani

  48. Endocrine surgery during COVID-19 pandemic: do we need an update of indications in Italy?

    Article • Endocrine, June 2020, Springer Science + Business Media

    Dr. Giorgio Grani

  49. Risk of Kidney Dysfunction IN Nafld

    Article • Current Pharmaceutical Design, April 2020, Bentham Science Publishers

    Dr. Giorgio Grani

  50. Fournier's gangrene during lenvatinib treatment: A case report

    Article • Molecular and Clinical Oncology, April 2020, Spandidos Publications

    Dr. Giorgio Grani

  51. Computer-aided diagnostic system for thyroid nodule sonographic evaluation outperforms the specificity of less experienced examiners

    Article • Journal of Ultrasound, April 2020, Springer Science + Business Media

    Dr. Giorgio Grani

  52. Performance of a dual-component molecular assay in cytologically indeterminate thyroid nodules

    Article • Endocrine, March 2020, Springer Science + Business Media

    Dr. Giorgio Grani

  53. Diagnostic Performance of Neck Ultrasonography in the Preoperative Evaluation for Extrathyroidal Extension of Suspicious Thyroid Nodules

    Article • Extremophiles, March 2020, Springer Science + Business Media

    Dr. Giorgio Grani

  54. Low-risk papillary thyroid microcarcinoma: Optimal management toward a more conservative approach

    Article • Journal of Surgical Oncology, March 2020, Wiley

    Dr. Giorgio Grani

  55. Exploring the molecular insights of concurrent composite mucoepidermoid carcinoma and papillary thyroid carcinoma

    Article • Endocrine, February 2020, Springer Science + Business Media

    Dr. Giorgio Grani

  56. Nodular Thyroid Disease in the Era of Precision Medicine

    Article • Frontiers in Endocrinology, January 2020, Frontiers

    Dr. Giorgio Grani

  57. Performance of contrast-enhanced ultrasound (CEUS) in assessing thyroid nodules: a systematic review and meta-analysis using histological standard of reference

    Article • La radiologia medica, January 2020, Springer Science + Business Media

    Dr. Giorgio Grani

  58. Does the Site of Origin of the Microcarcinoma with Respect to the Thyroid Surface Matter? A Multicenter Pathologic and Clinical Study for Risk Stratification

    Article • Cancers, January 2020, MDPI AG

    Dr. Giorgio Grani

  59. Can ultrasound systems for risk stratification of thyroid nodules identify follicular carcinoma?

    Article • Cancer Cytopathology, January 2020, Wiley

    Dr. Giorgio Grani, MD Marco Castellana

  60. Taller-Than-Wide Shape: A New Definition Improves the Specificity of TIRADS Systems

    Article • European Thyroid Journal, November 2019, Karger Publishers

    Dr. Giorgio Grani

  61. Clinically silent thyroid cancers: drop those needles and scalpels!

    Article • The Journal of Clinical Endocrinology & Metabolism, October 2019, Endocrine Society

    Dr. Giorgio Grani

  62. Comment on: BRAF mutation analysis by ARMS‐PCR refines thyroid nodule management

    Article • Clinical Endocrinology, October 2019, Wiley

    Dr. Giorgio Grani

  63. Screening for differentiated thyroid cancer in selected populations

    Article • The Lancet Diabetes & Endocrinology, October 2019, Elsevier

    Dr. Giorgio Grani

  64. Thyroid hormone therapy in differentiated thyroid cancer

    Article • Endocrine, October 2019, Springer Science + Business Media

    Dr. Giorgio Grani

  65. Real-world efficacy and safety of lenvatinib: data from a compassionate use in the treatment of radioactive iodine-refractory differentiated thyroid cancer patients in Italy

    Article • European Journal of Cancer, September 2019, Elsevier

    Dr. Giorgio Grani

  66. SONOGRAPHICALLY ESTIMATED THYROID NODULE MALIGNANCY RISK: STRENGTHS AND LIMITATIONS IN CLINICAL PRACTICE

    Article • Endocrine Practice, September 2019, AACE Corp (American Association of Clinical Endocrinologists)

    Dr. Giorgio Grani

  67. Molecular defects in thyroid dysgenesis

    Article • Clinical Genetics, August 2019, Wiley

    Dr. Giorgio Grani

  68. Prognosis of patients with differentiated thyroid carcinomas having a preoperative cytological report of indeterminate at low or high risk. A multicenter study

    Article • Endocrine, July 2019, Springer Science + Business Media

    Dr. Giorgio Grani

  69. Thyroid cancer patients with no evidence of disease: the need for repeat neck ultrasound

    Article • The Journal of Clinical Endocrinology & Metabolism, June 2019, Endocrine Society

    Dr. Giorgio Grani

  70. Changes in TSH levels in athyreotic patients with differentiated thyroid cancer during levothyroxine therapy: influence on dose adjustments

    Article • Journal of Endocrinological Investigation, June 2019, Springer Science + Business Media

    Dr. Giorgio Grani

  71. Prospective Evaluation of Semiquantitative Strain Ratio and Quantitative 2D Ultrasound Shear Wave Elastography (SWE) in Association with TIRADS Classification for Thyroid Nodule Characterization

    Article • Ultraschall in der Medizin - European Journal of Ultrasound, May 2019, Thieme Publishing Group

    Dr. Giorgio Grani

  72. Indeterminate thyroid nodules ( TIR 3A/ TIR 3B) according to the new Italian Reporting System for Thyroid Cytology: a cytomorphological study

    Article • Cytopathology, May 2019, Wiley

    Dr. Giorgio Grani

  73. Levothyroxine Treatment Increases Mortality in Patients with Heart Failure

    Article • Clinical Thyroidology, March 2019, Mary Ann Liebert Inc

    Dr. Giorgio Grani

  74. Is thyroid nodule location associated with malignancy risk?

    Article • ULTRASONOGRAPHY, November 2018, Korean Society of Ultrasound in Medicine

    Dr. Giorgio Grani

  75. IS IT WORTH SUPPRESSING TSH IN LOW- AND INTERMEDIATE-RISK PAPILLARY THYROID CANCER PATIENTS BEFORE THE FIRST DISEASE ASSESSMENT?

    Article • Endocrine Practice, November 2018, AACE Corp (American Association of Clinical Endocrinologists)

    Dr. Giorgio Grani

  76. A synonymous RET substitution enhances the oncogenic effect of an in-cis missense mutation by increasing constitutive splicing efficiency

    Article • PLoS Genetics, October 2018, PLOS

    Dr. Giorgio Grani

  77. Reducing the number of unnecessary thyroid biopsies while improving diagnostic accuracy: towards the “right” TIRADS

    Article • The Journal of Clinical Endocrinology & Metabolism, October 2018, Endocrine Society

    Dr. Giorgio Grani

  78. Thyroid nodule recurrence following lobo-isthmectomy: incidence, patient’s characteristics, and risk factors

    Article • Journal of Endocrinological Investigation, September 2018, Springer Science + Business Media

    Dr. Giorgio Grani

  79. Sonographically Estimated Risks of Malignancy for Thyroid Nodules Computed with Five Standard Classification Systems: Changes over Time and Their Relation to Malignancy

    Article • Thyroid, September 2018, Mary Ann Liebert Inc

    Dr. Giorgio Grani

  80. Follow-up of differentiated thyroid cancer – what should (and what should not) be done

    Article • Nature Reviews Endocrinology, August 2018, Springer Science + Business Media

    Dr. Giorgio Grani

  81. Sonographic presentation of metastases to the thyroid gland: a case-series

    Article • Journal of the Endocrine Society, June 2018, Endocrine Society

    Dr. Giorgio Grani

  82. The distinctive traits of Follicular thyroid cancer and Hürthle cell cancer

    Article • The Lancet Diabetes & Endocrinology, June 2018, Elsevier

    Dr. Giorgio Grani, Sebastiano Filetti

  83. Thyroid Dysfunction and Nonalcoholic Fatty Liver Disease: We Need New Larger and Well-Designed Longitudinal Studies

    Article • Digestive Diseases and Sciences, April 2018, Springer Science + Business Media

    Dr. Giorgio Grani

  84. Lack of association between obesity and aggressiveness of differentiated thyroid cancer

    Article • Journal of Endocrinological Investigation, April 2018, Springer Science + Business Media

    Dr. Giorgio Grani

  85. The Diagnosis and management of thyroid nodules

    Article • JAMA, March 2018, American Medical Association (AMA)

    Dr. Giorgio Grani

  86. What's new on differentiated thyroid cancer?

    Article • F1000Research, January 2018, Faculty of 1000, Ltd.

    LIVIA LAMARTINA, Dr. Giorgio Grani, Sebastiano Filetti

  87. The level of agreement between different clinicians in the evaluation of thyroid nodules

    Article • Endocrine Connections, December 2017, Bioscientifica

    Dr. Giorgio Grani

  88. Are Evidence-Based Guidelines Reflected in Clinical Practice? An Analysis of Prospectively Collected Data of the Italian Thyroid Cancer Observatory

    Article • Thyroid, December 2017, Mary Ann Liebert Inc

    Dr. Giorgio Grani, Professor Fabio Monzani

  89. 8th edition of the AJCC/TNM staging system of thyroid cancer: what to expect (ITCO#2)

    Article • Endocrine Related Cancer, November 2017, Bioscientifica

    Dr. Giorgio Grani

  90. Temporal Changes in Thyroid Nodule Volume: Lack of Effect on Paranodular Thyroid Tissue Volume

    Article • Thyroid, November 2017, Mary Ann Liebert Inc

    Dr. Giorgio Grani

  91. MicroRNA-based molecular classification of papillary thyroid carcinoma

    Article • International Journal of Oncology, April 2017, Spandidos Publications

    Dr. Giorgio Grani, Professor Fabio Monzani

  92. Identification of Thyroid-Associated Serum microRNA Profiles and Their Potential Use in Thyroid Cancer Follow-Up

    Article • Journal of the Endocrine Society, January 2017, Endocrine Society

    Sebastiano Filetti, Marialuisa Sponziello, Dr. Giorgio Grani, Diego Russo

  93. Ultrasonography scoring systems can rule out malignancy in cytologically indeterminate thyroid nodules

    Article • Endocrine, October 2016, Springer Science + Business Media

    Dr. Giorgio Grani

  94. Severe hypoglycemia in patients with known diabetes requiring emergency department care: A report from an Italian multicenter study

    Article • Journal of Clinical & Translational Endocrinology, September 2016, Elsevier

    Dr. Giorgio Grani, Prof Marco Giorgio Baroni

  95. Risk Stratification of Neck Lesions Detected Sonographically During the Follow-Up of Differentiated Thyroid Cancer

    Article • The Journal of Clinical Endocrinology & Metabolism, August 2016, Endocrine Society

    Dr. Giorgio Grani

  96. Grey-Scale Analysis Improves the Ultrasonographic Evaluation of Thyroid Nodules

    Article • Medicine, July 2015, Wolters Kluwer Health

    Dr. Giorgio Grani

  97. Association of Thyroid Diseases with Primary Extra-Thyroidal Malignancies in Women: Results of a Cross-Sectional Study of 6,386 Patients

    Article • PLoS ONE, March 2015, PLOS

    Dr. Giorgio Grani

  98. Influence of Thyrotropin and Thyroid Volume on Basal Serum Calcitonin

    Article • Experimental and Clinical Endocrinology & Diabetes, October 2014, Thieme Publishing Group

    Dr. Giorgio Grani

  99. A comprehensive score to diagnose Hashimoto’s thyroiditis

    Article • Endocrine, October 2014, Springer Science + Business Media

    Dr. Giorgio Grani

  100. Thyroglobulin in Lymph Node Fine-Needle Aspiration Washout

    Article • The Journal of Clinical Endocrinology & Metabolism, June 2014, Endocrine Society

    Dr. Giorgio Grani

  101. Thyroid autoimmunity and risk of malignancy in thyroid nodules submitted to fine‐needle aspiration cytology

    Article • Head & Neck, April 2014, Wiley

    Dr. Giorgio Grani

  102. Thyroglobulin in fine-needle aspiration wash-out diagnostic performance: a meta-analysis

    Article • Endocrine Abstracts, April 2013, Bioscientifica

    Dr. Giorgio Grani

  103. Serum calcitonin, thyrotropin, and goiter

    Article • Endocrine Abstracts, April 2013, Bioscientifica

    Dr. Giorgio Grani

  104. Thyroid Function in Infertile Patients Undergoing Assisted Reproduction

    Article • American Journal of Reproductive Immunology, March 2013, Wiley

    Dr. Giorgio Grani

  105. Intrinsic factors affecting adequacy of thyroid nodule fine‐needle aspiration cytology

    Article • Clinical Endocrinology, December 2012, Wiley

    Dr. Giorgio Grani

  106. Interpretation of serum calcitonin in patients with chronic autoimmune thyroiditis

    Article • March 2012, Bioscientifica

    Dr. Giorgio Grani

  107. Therapy of Hyperthyroidism in Pregnancy and Breastfeeding

    Article • Obstetrical & Gynecological Survey, June 2011, Wolters Kluwer Health

    Dr. Giorgio Grani

  108. Medical Treatment of Hyperthyroidism: State of the Art

    Article • Experimental and Clinical Endocrinology & Diabetes, May 2010, Thieme Publishing Group

    Dr. Giorgio Grani

  109. Diagnostic Accuracy of rhTSH Test with Neck Ultrasonography in Differentiated Thyroid Cancer Follow-up

    Article • Experimental and Clinical Endocrinology & Diabetes, December 2009, Thieme Publishing Group

    Dr. Giorgio Grani

  110. Medullary Thyroid Carcinoma and Tuberous Sclerosis

    Article • Endocrine Pathology, May 2009, Springer Science + Business Media

    Dr. Giorgio Grani