All Stories

  1. Kupffer Cells and Hepatocytes: A Key Relation in the Context of Canine Leishmaniasis

    Article • Microorganisms, September 2024, MDPI AG

    Dr Gabriela Maria Santos-Gomes

  2. Concanavalin A, lectin from Canavalia ensiformis seeds has Leishmania infantum antipromastigote activity mediated by carbohydrate recognition domain

    Article • Chemico-Biological Interactions, August 2024, Elsevier

    Dr Gabriela Maria Santos-Gomes

  3. Editorial: Neglected tropical diseases: tackling the challenges of a global world

    Article • Frontiers in Toxicology, April 2024, Frontiers

    Dr Gabriela Maria Santos-Gomes

  4. Chagas Disease: A Silent Threat for Dogs and Humans

    Article • International Journal of Molecular Sciences, March 2024, MDPI AG

    Dr Gabriela Maria Santos-Gomes

  5. Exploiting Leishmania—Primed Dendritic Cells as Potential Immunomodulators of Canine Immune Response

    Article • Cells, March 2024, MDPI AG

    Dr Gabriela Maria Santos-Gomes

  6. Insights on Host–Parasite Immunomodulation Mediated by Extracellular Vesicles of Cutaneous Leishmania shawi and Leishmania guyanensis

    Article • Cells, April 2023, MDPI AG

    Dr Gabriela Maria Santos-Gomes

  7. Parasitic Infection and Immunity—A Special Biomedicines Issue

    Article • Biomedicines, October 2022, MDPI AG

    Dr Gabriela Maria Santos-Gomes

  8. Quantum Biochemistry Screening and In Vitro Evaluation of Leishmania Metalloproteinase Inhibitors

    Article • International Journal of Molecular Sciences, August 2022, MDPI AG

    Dr Gabriela Maria Santos-Gomes

  9. A Questionnaire-Based Survey on the Long-Term Management of Canine Leishmaniosis by Veterinary Practitioners

    Article • Animals, March 2022, MDPI AG

    Dr Gabriela Maria Santos-Gomes, Rute Santos

  10. Zoonotic Visceral Leishmaniasis: New Insights on Innate Immune Response by Blood Macrophages and Liver Kupffer Cells to Leishmania infantum Parasites

    Article • Biology, January 2022, MDPI AG

    Dr Gabriela Maria Santos-Gomes

  11. African Trypanosomiasis: Extracellular Vesicles Shed by Trypanosoma brucei brucei Manipulate Host Mononuclear Cells

    Article • Biomedicines, August 2021, MDPI AG

    Dr Gabriela Maria Santos-Gomes

  12. 3D-Hepatocyte Culture Applied to Parasitology: Immune Activation of Canine Hepatic Spheroids Exposed to Leishmania infantum

    Article • Biomedicines, December 2020, MDPI AG

    Dr Gabriela Maria Santos-Gomes

  13. Human toxoplasmosis in Mozambique: gaps in knowledge and research opportunities

    Article • Parasites & Vectors, November 2020, Springer Science + Business Media

    Dr Gabriela Maria Santos-Gomes

  14. Prognostic Factors and Life Expectancy in Canine Leishmaniosis

    Article • Veterinary Sciences, September 2020, MDPI AG

    Dr Gabriela Maria Santos-Gomes, Rute Santos

  15. Immunophenotyping of Peripheral Blood, Lymph Node, and Bone Marrow T Lymphocytes During Canine Leishmaniosis and the Impact of Antileishmanial Chemotherapy

    Article • Frontiers in Veterinary Science, July 2020, Frontiers

    Dr Gabriela Maria Santos-Gomes

  16. Leishmaniosis: New Insights in a Changing World

    Article • January 2020, Springer Science + Business Media

    Dr Gabriela Maria Santos-Gomes

  17. Cutaneous Leishmaniasis: The Complexity of Host’s Effective Immune Response against a Polymorphic Parasitic Disease

    Article • Journal of Immunology Research, December 2019, Hindawi Publishing Corporation

    Dr Gabriela Maria Santos-Gomes, Áurea Gabriel

  18. Development of Dog Immune System: From in Uterus to Elderly

    Article • Veterinary Sciences, October 2019, MDPI AG

    Dr Gabriela Maria Santos-Gomes

  19. Meglumine Antimoniate and Miltefosine Combined With Allopurinol Sustain Pro-inflammatory Immune Environments During Canine Leishmaniosis Treatment

    Article • Frontiers in Veterinary Science, October 2019, Frontiers

    Dr Gabriela Maria Santos-Gomes

  20. Canine neutrophils cooperate with macrophages in the early stages of Leishmania infantum in vitro infection

    Article • Parasite Immunology, March 2019, Wiley

    Dr Gabriela Maria Santos-Gomes

  21. Intracellular and extracellular effector activity of mouse neutrophils in response to cutaneous and visceral Leishmania parasites

    Article • Cellular Immunology, January 2019, Elsevier

    Dr Gabriela Maria Santos-Gomes

  22. Dog hepatocytes are key effector cells in the liver innate immune response to Leishmania infantum

    Article • Parasitology, December 2018, Cambridge University Press

    Dr Gabriela Maria Santos-Gomes

  23. Conventional Versus Natural Alternative Treatments for Leishmaniasis: A Review

    Article • Current Topics in Medicinal Chemistry, November 2018, Bentham Science Publishers

    Dr Gabriela Maria Santos-Gomes, Dr Felipe Passero

  24. THREATENING THE ROOFS OVER OUR HEADS: EXPLORING THE ROLE OF ACADEMIC INSTITUTION EXPANSION IN THE GENTRIFICATION AND DISPLACEMENT OF RESIDENTS IN ECONOMICALLY DISADVANTAGED, URBAN COMMUNITIES

    Article • November 2018, IATED Academy, S.L.

    Dr Gabriela Maria Santos-Gomes

  25. Canine neutrophils activate effector mechanisms in response to Leishmania infantum

    Article • Veterinary Parasitology, December 2017, Elsevier

    Dr Gabriela Maria Santos-Gomes

  26. Leishmania infantum exerts immunomodulation in canine Kupffer cells reverted by meglumine antimoniate

    Article • Comparative Immunology Microbiology and Infectious Diseases, December 2017, Elsevier

    Dr Gabriela Maria Santos-Gomes

  27. Corrigendum to “Therapeutic effect of ursolic acid in experimental visceral leishmaniasis” [Int. J. Parasitol. Drugs Drug Resist. 7 (2017) 1–11]

    Article • International Journal for Parasitology Drugs and Drug Resistance, August 2017, Elsevier

    Dr Gabriela Maria Santos-Gomes

  28. Therapeutic effect of ursolic acid in experimental visceral leishmaniasis

    Article • International Journal for Parasitology Drugs and Drug Resistance, April 2017, Elsevier

    Dr Gabriela Maria Santos-Gomes

  29. A field evaluation of an isothermal DNA amplification assay for the detection of Theileria annulata infection in cattle

    Article • Molecular and Cellular Probes, February 2017, Elsevier

    Dr Gabriela Maria Santos-Gomes

  30. Leishmania infantum antigens modulate memory cell subsets of liver resident T lymphocyte

    Article • Immunobiology, February 2017, Elsevier

    Dr Gabriela Maria Santos-Gomes

  31. Population diversity of Theileria annulata in Portugal

    Article • Infection Genetics and Evolution, August 2016, Elsevier

    Dr Gabriela Maria Santos-Gomes

  32. Successful treatment of feline leishmaniosis using a combination of allopurinol and N-methyl-glucamine antimoniate

    Article • Journal of Feline Medicine and Surgery Open Reports, January 2016, SAGE Publications

    Professor Miguel Carreira, Dr Gabriela Maria Santos-Gomes

  33. The Effect of Ursolic Acid on Leishmania (Leishmania) amazonensis Is Related to Programed Cell Death and Presents Therapeutic Potential in Experimental Cutaneous Leishmaniasis

    Article • PLoS ONE, December 2015, PLOS

    Dr Gabriela Maria Santos-Gomes

  34. Hemisynthetic trifluralin analogues incorporated in liposomes for the treatment of leishmanial infections

    Article • European Journal of Pharmaceutics and Biopharmaceutics, June 2015, Elsevier

    Dr Gabriela Maria Santos-Gomes

  35. New insights into neutrophil and Leishmania infantum in vitro immune interactions

    Article • Comparative Immunology Microbiology and Infectious Diseases, June 2015, Elsevier

    Dr Gabriela Maria Santos-Gomes

  36. Plants Used in Traditional Medicine: Extracts and Secondary Metabolites Exhibiting Antileishmanial Activity

    Article • Current Clinical Pharmacology, August 2014, Bentham Science Publishers

    Dr Felipe Passero, Dr Gabriela Maria Santos-Gomes

  37. Immunization with the Leishmania infantum recombinant cyclophilin protein 1 confers partial protection to subsequent parasite infection and generates specific memory T cells

    Article • Vaccine, March 2014, Elsevier

    Dr Gabriela Maria Santos-Gomes

  38. Development and field trial of a Tams1-targeted isothermal DNA amplification (Tams1-lamp) assay for detection of Theileria annulata in cattle

    Article • Parasites & Vectors, January 2014, Springer Science + Business Media

    Dr Gabriela Maria Santos-Gomes

  39. Generation of an antibody that recognizes Plasmodium chabaudi cysteine protease (chabaupain-1) in both sexual and asexual parasite life cycle and evaluation of chabaupain-1 vaccine potential

    Article • Experimental Parasitology, September 2013, Elsevier

    Dr Gabriela Maria Santos-Gomes

  40. Detection of Theileria and Babesia infections amongst asymptomatic cattle in Portugal

    Article • Ticks and Tick-borne Diseases, February 2013, Elsevier

    Dr Gabriela Maria Santos-Gomes

  41. Role of neutrophils in parasite persistence and in host immunity during the initial phase of Leishmania chagasi experimental infection

    Article • Frontiers in Immunology, January 2013, Frontiers

    Dr Gabriela Maria Santos-Gomes

  42. In Vivo Antileishmanial Activity of Plant-Based Secondary Metabolites

    Article • January 2013, Elsevier

    Dr Gabriela Maria Santos-Gomes

  43. Canine leishmaniosis. Modulation of macrophage/lymphocyte interactions by L. infantum

    Article • Veterinary Parasitology, October 2012, Elsevier

    Dr Gabriela Maria Santos-Gomes

  44. Cytokine Gene Expression in the Tissues of Dogs Infected by Leishmania infantum

    Article • Journal of Comparative Pathology, November 2011, Elsevier

    Dr Gabriela Maria Santos-Gomes

  45. Analysis of the protective potential of antigens released by Leishmania (Viannia) shawi promastigotes

    Article • Archives of Dermatological Research, September 2011, Springer Science + Business Media

    Dr Gabriela Maria Santos-Gomes

  46. Vaccines for the Leishmaniases: Proposals for a Research Agenda

    Article • PLoS Neglected Tropical Diseases, March 2011, PLOS

    Dr Gabriela Maria Santos-Gomes

  47. Canine leishmaniosis. Immunophenotypic profile of leukocytes in different compartments of symptomatic, asymptomatic and treated dogs

    Article • Veterinary Immunology and Immunopathology, October 2010, Elsevier

    Dr Gabriela Maria Santos-Gomes

  48. Histopathology, humoral and cellular immune response in the murine model of Leishmania (Viannia) shawi

    Article • Parasitology International, June 2010, Elsevier

    Dr Gabriela Maria Santos-Gomes

  49. Exocytosis of serine proteases and modulation of neutrophil inflammatory response in the presence of Leishmania infantum

    Article • Cytokine, October 2009, Elsevier

    Dr Gabriela Maria Santos-Gomes

  50. Differential expression of cytokine genes among sickle-cell-trait (HbAS) and normal (HbAA) children infected withPlasmodium falciparum

    Article • Annals of Tropical Medicine and Parasitology, June 2009, Taylor & Francis

    Dr Gabriela Maria Santos-Gomes

  51. Identification of regulatory T cells during experimental Leishmania infantum infection

    Article • Immunobiology, February 2009, Elsevier

    Dr Gabriela Maria Santos-Gomes

  52. Efficacy of the liposome trifluralin in the treatment of experimental canine leishmaniosis

    Article • The Veterinary Journal, October 2008, Elsevier

    Dr Gabriela Maria Santos-Gomes

  53. Immunization with Leishmania infantum released proteins confers partial protection against parasite infection with a predominant Th1 specific immune response

    Article • Vaccine, June 2007, Elsevier

    Dr Gabriela Maria Santos-Gomes

  54. Intra-specific variability of virulence in Leishmania infantum zymodeme MON-1 strains

    Article • Comparative Immunology Microbiology and Infectious Diseases, January 2007, Elsevier

    Dr Gabriela Maria Santos-Gomes

  55. Canine Leishmaniasis Chemotherapy: Dog's Clinical Condition and Risk of Leishmania Transmission

    Article • Journal of Veterinary Medicine Series A, November 2006, Wiley

    Dr Gabriela Maria Santos-Gomes

  56. Leishmaniasis in Portugal: enzyme polymorphism of Leishmania infantum based on the identification of 213 strains

    Article • Tropical Medicine & International Health, November 2006, Wiley

    Dr Gabriela Maria Santos-Gomes

  57. H-2 complex influences cytokine gene expression in Leishmania infantum-infected macrophages

    Article • Cellular Immunology, October 2006, Elsevier

    Dr Gabriela Maria Santos-Gomes

  58. Leishmania infantum released proteins specifically regulate cytokine expression and production patterns by CD4+ and CD8+ T cells

    Article • Acta Tropica, March 2006, Elsevier

    Dr Gabriela Maria Santos-Gomes

  59. Leishmania infantum: soluble proteins released by the parasite exert differential effects on host immune response

    Article • Experimental Parasitology, February 2005, Elsevier

    Dr Gabriela Maria Santos-Gomes

  60. Dynamics of CD62L/CD45RB CD4+ and CD8+ lymphocyte subsets in hepatic and splenic tissues during murine visceral leishmaniasis

    Article • Immunology Letters, August 2004, Elsevier

    Dr Gabriela Maria Santos-Gomes

  61. Hepatic cellular immune responses in mice with “cure” and “non-cure” phenotype toLeishmania infantuminfection: importance of CD8+T cells and TGF-β production

    Article • FEMS Immunology & Medical Microbiology, May 2004, Oxford University Press (OUP)

    Dr Gabriela Maria Santos-Gomes

  62. Experimental canine leishmaniasis: evolution of infection following re-challenge with Leishmania infantum

    Article • Acta Tropica, July 2003, Elsevier

    Dr Gabriela Maria Santos-Gomes

  63. Cytokine expression during the outcome of canine experimental infection by Leishmania infantum

    Article • Veterinary Immunology and Immunopathology, September 2002, Elsevier

    Dr Gabriela Maria Santos-Gomes

  64. Cell mediated immunity and specific IgG1 and IgG2 antibody response in natural and experimental canine leishmaniosis

    Article • Veterinary Immunology and Immunopathology, May 2001, Elsevier

    Dr Gabriela Maria Santos-Gomes

  65. Infectivity of promastigotes and amastigotes of Leishmania infantum in a canine model for leishmaniosis

    Article • Veterinary Parasitology, October 2000, Elsevier

    Dr Gabriela Maria Santos-Gomes

  66. Canine experimental infection: intradermal inoculation of Leishmania infantum promastigotes

    Article • Memórias do Instituto Oswaldo Cruz, April 2000, FapUNIFESP (SciELO)

    Dr Gabriela Maria Santos-Gomes

  67. The Effect of Chloroquine on the Production of Interferon-g, Interleukin (IL)-4, IL-6, and IL-10 in Plasmodium chabaudi chabaudi in Infected C57BL6 Mice

    Article • Journal of Parasitology, October 1999, JSTOR

    Dr Gabriela Maria Santos-Gomes

  68. HIV/Leishmania co-infections in Portugal: diagnosis and isoenzyme characterization of Leishmania

    Article • Annals of Tropical Medicine and Parasitology, June 1997, Taylor & Francis

    Dr Gabriela Maria Santos-Gomes

  69. HIV/ Leishmania co-infections in Portugal: diagnosis and isoenzyme characterization of Leishmania

    Article • Annals of Tropical Medicine and Parasitology, June 1997, Taylor & Francis

    Dr Gabriela Maria Santos-Gomes

  70. Reliability of serological methods for detection of leishmaniasis in portuguese domestic and wild reservoirs

    Article • Memórias do Instituto Oswaldo Cruz, December 1996, FapUNIFESP (SciELO)

    Dr Gabriela Maria Santos-Gomes

  71. The isolation ofLeishmania donovanimon-18, from an aids patient in Portugal: possible needle transmission

    Article • Parasite, December 1994, EDP Sciences

    Dr Gabriela Maria Santos-Gomes

  72. HIV-Leishmania co-infection in Portugal: isolation of Leishmania infantum MON-24

    Article • Transactions of the Royal Society of Tropical Medicine and Hygiene, July 1994, Oxford University Press (OUP)

    Dr Gabriela Maria Santos-Gomes

  73. An experimental model for canine visceral leishmaniasis

    Article • Parasite Immunology, September 1991, Wiley

    Dr Gabriela Maria Santos-Gomes

  74. Canine Leishmaniasis: Pathological and Ecological Factors Influencing Transmission of Infection

    Article • Journal of Parasitology, August 1991, JSTOR

    Dr Gabriela Maria Santos-Gomes